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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:18093 term browser browse the term
Definition:A 4,5-dihydrocortisone that has beta- configuration at position 5.
Synonyms:related_synonym: 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione;   4,5beta-Dihydrocortisone;   5-dihydrocortisone;   5beta-Pregnane-17alpha,21-diol-3,11,20-trione;   Formula=C21H30O5;   InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12,14-15,18,22,26H,3-11H2,1-2H3/t12-,14+,15+,18-,19+,20+,21+/m1/s1;   InChIKey=YCLWEYIBFOLMEM-FNLRALKVSA-N;   SMILES=[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@](O)(C(=O)CO)[C@@]4(C)CC(=O)[C@]3([H])[C@@]1(C)CCC(=O)C2
 alt_id: CHEBI:11927;   CHEBI:1753;   CHEBI:20277;   CHEBI:785
 xref: Beilstein:3222844;   CAS:68-54-2;   KEGG:C05469;   LIPID_MAPS_instance:LMST02030095
 xref_mesh: MESH:C045993

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17,21-dihydroxy-5beta-pregnane-3,11,20-trione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c1 aldo-keto reductase family 1, member C1 increases reduction ISO AKR1C4 protein results in increased reduction of 5-dihydrocortisone CTD PMID:8543560 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      group 19722
        organic group 18718
          3-oxo-Delta(4)-steroid group 9122
            3-oxo-Delta(4) steroid 9122
              cortisone 26
                4,5-dihydrocortisone 1
                  17,21-dihydroxy-5beta-pregnane-3,11,20-trione 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      ketone 16957
                                        oxyketone 8674
                                          alpha-oxyketone 8674
                                            alpha-hydroxy ketone 8674
                                              primary alpha-hydroxy ketone 7544
                                                cortisone 26
                                                  4,5-dihydrocortisone 1
                                                    17,21-dihydroxy-5beta-pregnane-3,11,20-trione 1
paths to the root