Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:indol-3-ylacetaldehyde
go back to main search page
Accession:CHEBI:18086 term browser browse the term
Definition:An indoleacetaldehyde that is acetaldehyde in which one of the methyl hydrogens are replaced by a indol-3-yl group. It is an intermediate metabolite in the metabolism of tryptophan.
Synonyms:related_synonym: 1H-Indol-3-ylacetaldehyde;   1H-Indole-3-acetaldehyde;   2-(Indol-3-yl)acetaldehyde;   Formula=C10H9NO;   InChI=1S/C10H9NO/c12-6-5-8-7-11-10-4-2-1-3-9(8)10/h1-4,6-7,11H,5H2;   InChIKey=WHOOUMGHGSPMGR-UHFFFAOYSA-N;   Indoleacetaldehyde;   SMILES=O=CCc1c[nH]c2ccccc12;   indole-3-acetaldehyde
 alt_id: CHEBI:11477;   CHEBI:14445;   CHEBI:24798;   CHEBI:5902
 xref: Beilstein:121586;   CAS:2591-98-2;   HMDB:HMDB0001190;   KEGG:C00637;   KNApSAcK:C00000109
 xref_mesh: MESH:C001655
 xref: MetaCyc:INDOLE_ACETALDEHYDE;   PMID:20217460;   PMID:22274708;   PMID:4015706;   PMID:4031860;   PMID:6862384;   Reaxys:121586

show annotations for term's descendants           Sort by:
 
indol-3-ylacetaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO indoleacetaldehyde metabolite results in decreased activity of CYP1A1 protein CTD PMID:26686552 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Maoa monoamine oxidase A multiple interactions
increases chemical synthesis		 ISO [[MAOA protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indoleacetaldehyde] which results in increased chemical synthesis of 6-formylindolo(3,2-b)carbazole; [MAOA protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indoleacetaldehyde
MAOA protein results in increased chemical synthesis of indoleacetaldehyde		 CTD PMID:26686552 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722 		JBrowse link
G Maob monoamine oxidase B multiple interactions
increases chemical synthesis		 ISO [[MAOB protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indoleacetaldehyde] which results in increased chemical synthesis of 6-formylindolo(3,2-b)carbazole; [MAOB protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indoleacetaldehyde
MAOB protein results in increased chemical synthesis of indoleacetaldehyde		 CTD PMID:26686552 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      chemical role 19250
        oxidising agent 9263
          acetaldehyde 543
            indoleacetaldehyde 3
              indol-3-ylacetaldehyde 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        carboacyl group 17348
                                          univalent carboacyl group 17348
                                            formyl group 7847
                                              aldehyde 7847
                                                acetaldehyde 543
                                                  indoleacetaldehyde 3
                                                    indol-3-ylacetaldehyde 3
paths to the root

Contact Us |  About Us |  License CC BY 4.0 |  Legal Disclaimer |  © Medical College of Wisconsin
NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.