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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:indol-3-ylacetaldehyde
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Accession:CHEBI:18086 term browser browse the term
Definition:An indoleacetaldehyde that is acetaldehyde in which one of the methyl hydrogens are replaced by a indol-3-yl group. It is an intermediate metabolite in the metabolism of tryptophan.
Synonyms:related_synonym: 1H-Indol-3-ylacetaldehyde;   1H-Indole-3-acetaldehyde;   2-(Indol-3-yl)acetaldehyde;   Formula=C10H9NO;   InChI=1S/C10H9NO/c12-6-5-8-7-11-10-4-2-1-3-9(8)10/h1-4,6-7,11H,5H2;   InChIKey=WHOOUMGHGSPMGR-UHFFFAOYSA-N;   Indoleacetaldehyde;   SMILES=O=CCc1c[nH]c2ccccc12;   indole-3-acetaldehyde
 alt_id: CHEBI:11477;   CHEBI:14445;   CHEBI:24798;   CHEBI:5902
 xref: Beilstein:121586;   CAS:2591-98-2;   HMDB:HMDB0001190;   KEGG:C00637;   KNApSAcK:C00000109
 xref_mesh: MESH:C001655
 xref: MetaCyc:INDOLE_ACETALDEHYDE;   PMID:20217460;   PMID:22274708;   PMID:4015706;   PMID:4031860;   PMID:6862384;   Reaxys:121586


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indol-3-ylacetaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO indole-3-acetaldehyde metabolite results in decreased activity of CYP1A1 protein CTD PMID:26686552 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Maoa monoamine oxidase A multiple interactions
increases chemical synthesis		 ISO [[MAOA protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indole-3-acetaldehyde] which results in increased chemical synthesis of 6-formylindolo(3,2-b)carbazole; [MAOA protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indole-3-acetaldehyde
MAOA protein results in increased chemical synthesis of indole-3-acetaldehyde		 CTD PMID:26686552 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Maob monoamine oxidase B multiple interactions
increases chemical synthesis		 ISO [[MAOB protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indole-3-acetaldehyde] which results in increased chemical synthesis of 6-formylindolo(3,2-b)carbazole; [MAOB protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indole-3-acetaldehyde
MAOB protein results in increased chemical synthesis of indole-3-acetaldehyde		 CTD PMID:26686552 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    role 19790
      chemical role 19421
        oxidising agent 11213
          acetaldehyde 556
            indoleacetaldehyde 3
              indol-3-ylacetaldehyde 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic group 18905
                              organic divalent group 18887
                                organodiyl group 18887
                                  carbonyl group 18853
                                    carbonyl compound 18853
                                      carboxylic acid 18569
                                        carboacyl group 17687
                                          univalent carboacyl group 17687
                                            formyl group 8841
                                              aldehyde 8841
                                                acetaldehyde 556
                                                  indoleacetaldehyde 3
                                                    indol-3-ylacetaldehyde 3
paths to the root