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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:indol-3-ylacetaldehyde
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Accession:CHEBI:18086 term browser browse the term
Definition:An indoleacetaldehyde that is acetaldehyde in which one of the methyl hydrogens are replaced by a indol-3-yl group. It is an intermediate metabolite in the metabolism of tryptophan.
Synonyms:related_synonym: 1H-Indol-3-ylacetaldehyde;   1H-Indole-3-acetaldehyde;   2-(Indol-3-yl)acetaldehyde;   Formula=C10H9NO;   InChI=1S/C10H9NO/c12-6-5-8-7-11-10-4-2-1-3-9(8)10/h1-4,6-7,11H,5H2;   InChIKey=WHOOUMGHGSPMGR-UHFFFAOYSA-N;   Indoleacetaldehyde;   SMILES=O=CCc1c[nH]c2ccccc12;   indole-3-acetaldehyde
 alt_id: CHEBI:11477;   CHEBI:14445;   CHEBI:24798;   CHEBI:5902
 xref: Beilstein:121586;   CAS:2591-98-2;   HMDB:HMDB0001190;   KEGG:C00637;   KNApSAcK:C00000109
 xref_mesh: MESH:C001655
 xref: MetaCyc:INDOLE_ACETALDEHYDE;   PMID:20217460;   PMID:22274708;   PMID:4015706;   PMID:4031860;   PMID:6862384;   Reaxys:121586



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indol-3-ylacetaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO indole-3-acetaldehyde metabolite results in decreased activity of CYP1A1 protein CTD PMID:26686552 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Maoa monoamine oxidase A multiple interactions
increases chemical synthesis
ISO [[MAOA protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indole-3-acetaldehyde] which results in increased chemical synthesis of 6-formylindolo(3,2-b)carbazole; [MAOA protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indole-3-acetaldehyde
MAOA protein results in increased chemical synthesis of indole-3-acetaldehyde
CTD PMID:26686552 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Maob monoamine oxidase B multiple interactions
increases chemical synthesis
ISO [[MAOB protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indole-3-acetaldehyde] which results in increased chemical synthesis of 6-formylindolo(3,2-b)carbazole; [MAOB protein results in decreased amination of tryptamine] which results in increased chemical synthesis of indole-3-acetaldehyde
MAOB protein results in increased chemical synthesis of indole-3-acetaldehyde
CTD PMID:26686552 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19860
    role 19832
      chemical role 19462
        oxidising agent 12013
          acetaldehyde 556
            indoleacetaldehyde 3
              indol-3-ylacetaldehyde 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19860
    subatomic particle 19858
      composite particle 19858
        hadron 19858
          baryon 19858
            nucleon 19858
              atomic nucleus 19858
                atom 19858
                  main group element atom 19804
                    p-block element atom 19804
                      carbon group element atom 19745
                        carbon atom 19741
                          organic molecular entity 19741
                            heteroorganic entity 19494
                              organochalcogen compound 19257
                                organooxygen compound 19173
                                  carbon oxoacid 18641
                                    carboxylic acid 18638
                                      carboacyl group 17705
                                        univalent carboacyl group 17705
                                          formyl group 9005
                                            aldehyde 9005
                                              acetaldehyde 556
                                                indoleacetaldehyde 3
                                                  indol-3-ylacetaldehyde 3
paths to the root