The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A member of the class of aminoxyls that is TEMPO carrying a hydroxy substituent at position 4. It is a radical scavenger which exhibits anti-inflammatory and analgesic properties.
tempol inhibits the reaction [AGT protein modified form results in increased expression of S1PR1 mRNA]; tempol inhibits the reaction [AGT protein modified form results in increased expression of S1PR1 protein]; tempol inhibits the reaction [AGT protein results in decreased export of Sodium]; tempol inhibits the reaction [AGT protein results in increased abundance of Oxygen]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]] tempol inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA]; tempol inhibits the reaction [AGT protein modified form results in increased abundance of Superoxides]; tempol inhibits the reaction [AGT protein results in increased expression of EDN1 mRNA]; tempol inhibits the reaction [ATP7A mutant form inhibits the reaction [AGT protein results in increased susceptibility to Acetylcholine]]; tempol inhibits the reaction [ATP7A mutant form promotes the reaction [AGT protein results in increased abundance of Superoxides]]; tempol promotes the reaction [ATOX1 protein inhibits the reaction [AGT protein modified form results in decreased susceptibility to Acetylcholine]]
tempol inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA]
tempol inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA]
tempol inhibits the reaction [APOE gene mutant form results in decreased susceptibility to Arachidonic Acid] tempol inhibits the reaction [APOE gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]]
tempol inhibits the reaction [ATP7A mutant form inhibits the reaction [AGT protein results in increased susceptibility to Acetylcholine]]; tempol inhibits the reaction [ATP7A mutant form promotes the reaction [AGT protein results in increased abundance of Superoxides]]
tempol inhibits the reaction [7-ketocholesterol results in increased activity of CASP1 protein]; tempol inhibits the reaction [Cholesterol analog results in increased activity of CASP1 protein]
[tempol co-treated with UCF 101 co-treated with acetovanillone] inhibits the reaction [S-Nitrosoglutathione results in increased activity of CASP3 protein]; tempol inhibits the reaction [[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP3 protein] tempol results in decreased expression of CASP3 protein
tempol inhibits the reaction [[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP7 protein]; tempol results in increased cleavage of and results in increased activity of CASP7 protein
tempol promotes the reaction [CDKN1A protein results in increased susceptibility to Doxorubicin] tempol results in increased expression of CDKN1A protein
tempol results in decreased expression of EDN1 mRNA; tempol results in decreased expression of EDN1 protein tempol inhibits the reaction [AGT protein results in increased expression of EDN1 mRNA]
tempol inhibits the reaction [sodium arsenate results in increased expression of EPO mRNA]; tempol inhibits the reaction [sodium arsenate results in increased expression of EPO protein]
NFE2L2 protein affects the reaction [tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of FTH1 protein]]; tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of FTH1 protein]
tempol inhibits the reaction [Aldosterone results in increased expression of GCLC protein] NFE2L2 protein affects the reaction [tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of GCLC protein]]; tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of GCLC protein]; tempol promotes the reaction [NFE2L2 protein inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of GCLC protein]]
NFE2L2 protein affects the reaction [tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of GCLM protein]]; tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of GCLM protein]; tempol promotes the reaction [NFE2L2 protein inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of GCLM protein]]
[tempol co-treated with Tobacco Smoke Pollution] results in increased expression of GPX2 mRNA; tempol promotes the reaction [Tobacco Smoke Pollution results in increased expression of GPX2 protein]
tempol results in increased expression of GPX4 mRNA NFE2L2 protein affects the reaction [tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of GPX4 protein]]; tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of GPX4 protein]
tempol inhibits the reaction [Sodium Chloride results in increased expression of HIF1A protein] tempol results in increased expression of HIF1A protein
tempol inhibits the reaction [Asbestos, Crocidolite results in decreased activity of HMGCR protein]; tempol inhibits the reaction [Vitamin K 3 results in decreased activity of HMGCR protein]
tempol results in increased expression of HMOX1 mRNA [tempol co-treated with Tobacco Smoke Pollution] results in increased expression of HMOX1 mRNA; tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of HMOX1 protein] NFE2L2 protein affects the reaction [tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of HMOX1 protein]]; tempol promotes the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of HMOX1 protein]
tempol inhibits the reaction [Phenol results in decreased expression of IL1B mRNA] tempol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of IL1B mRNA]
tempol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of IL6 mRNA] tempol inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of and results in increased secretion of IL6 protein]
tempol inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]]
tempol inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein] NFE2L2 protein affects the reaction [tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of FTH1 protein]]; NFE2L2 protein affects the reaction [tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of GPX4 protein]]; NFE2L2 protein affects the reaction [tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of NFE2L2 protein]]; NFE2L2 protein affects the reaction [tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of SLC7A11 protein]]; NFE2L2 protein affects the reaction [tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of HMOX1 protein]]; NFE2L2 protein affects the reaction [tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of GCLC protein]]; NFE2L2 protein affects the reaction [tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of GCLM protein]]; tempol promotes the reaction [NFE2L2 protein inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of NFE2L2 protein]]; tempol promotes the reaction [NFE2L2 protein inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of SLC7A11 protein]]; tempol promotes the reaction [NFE2L2 protein inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of GCLC protein]]; tempol promotes the reaction [NFE2L2 protein inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of GCLM protein]] tempol results in decreased ubiquitination of NFE2L2 protein
tempol inhibits the reaction [copper histidine results in increased activity of NFKB1 protein]; tempol inhibits the reaction [Copper results in increased activity of NFKB1 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tempol results in increased phosphorylation of NOS1 protein]; tempol inhibits the reaction [lead acetate results in increased expression of NOS1 protein]; tempol inhibits the reaction [Phenol results in decreased expression of NOS1 mRNA]
tempol inhibits the reaction [copper histidine results in increased expression of NOS2 protein]; tempol inhibits the reaction [Copper results in increased expression of NOS2 protein]; tempol inhibits the reaction [lead acetate results in increased expression of NOS2 protein]
tempol inhibits the reaction [lead acetate results in increased expression of NOS3 protein]; tempol inhibits the reaction [Sodium Chloride results in decreased expression of NOS3 protein]
tempol inhibits the reaction [Ketoconazole results in increased expression of PRKN mRNA]; tempol inhibits the reaction [Ketoconazole results in increased expression of PRKN protein]
tempol inhibits the reaction [copper histidine results in increased expression of PTGS2 mRNA]; tempol inhibits the reaction [Copper results in increased expression of PTGS2 mRNA]; tempol inhibits the reaction [Lead results in increased expression of PTGS2 mRNA]; tempol inhibits the reaction [Mercuric Chloride results in increased expression of PTGS2 mRNA]
tempol inhibits the reaction [Benzene results in increased phosphorylation of RELA protein] tempol inhibits the reaction [copper histidine results in increased activity of RELA protein]; tempol inhibits the reaction [Copper results in increased activity of RELA protein]
tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]] tempol inhibits the reaction [Asbestos, Crocidolite inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]]; tempol inhibits the reaction [Asbestos, Crocidolite results in decreased prenylation of RHOA protein]; tempol inhibits the reaction [Vitamin K 3 inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]]; tempol inhibits the reaction [Vitamin K 3 results in decreased prenylation of RHOA protein]
tempol inhibits the reaction [AGT protein modified form results in increased expression of S1PR1 mRNA]; tempol inhibits the reaction [AGT protein modified form results in increased expression of S1PR1 protein]
tempol inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA]; tempol inhibits the reaction [Hydrogen Peroxide results in increased expression of SERPINE1 mRNA]
tempol inhibits the reaction [Manganese results in increased expression of SLC12A2 protein]; tempol inhibits the reaction [Manganese results in increased oxidation of SLC12A2 protein]
tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of SLC7A11 protein] NFE2L2 protein affects the reaction [tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of SLC7A11 protein]]; tempol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of SLC7A11 protein]; tempol promotes the reaction [NFE2L2 protein inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of SLC7A11 protein]]
tempol affects the expression of SOD2 protein tempol inhibits the reaction [Isoflurane results in decreased expression of and results in decreased activity of SOD2 protein]; tempol inhibits the reaction [Nitric Oxide deficiency results in increased expression of SOD2 protein] tempol affects the reaction [SOD2 protein affects the susceptibility to Acetylcholine]; tempol inhibits the reaction [Capsaicin results in decreased activity of SOD2 protein]; tempol inhibits the reaction [Capsaicin results in increased expression of SOD2 protein modified form]
tempol affects the expression of TGFB1 protein tempol inhibits the reaction [Aldosterone results in increased expression of TGFB1 mRNA]; tempol inhibits the reaction [Sodium Chloride results in increased expression of TGFB1 protein] tempol inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of TGFB1 mRNA]
tempol inhibits the reaction [[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP3 protein]; tempol inhibits the reaction [[sulindac sulfide co-treated with TNF protein] results in increased activity of CASP7 protein] tempol inhibits the reaction [copper histidine results in increased expression of TNF protein]; tempol inhibits the reaction [Copper results in increased expression of TNF protein] tempol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; tempol inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TNF mRNA]
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