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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:oxamic acid
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Accession:CHEBI:18058 term browser browse the term
Definition:A dicarboxylic acid monoamide resulting from the formal condensation of one of the carboxy groups of oxalic acid with ammonia.
Synonyms:related_synonym: Formula=C2H3NO3;   Glycine, 2-oxo-;   InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6);   InChIKey=SOWBFZRMHSNYGE-UHFFFAOYSA-N;   Oxalic monoamide;   Oxamate;   SMILES=NC(=O)C(O)=O;   amino(oxo)acetic acid
 alt_id: CHEBI:14708;   CHEBI:25740;   CHEBI:44589;   CHEBI:7818
 xref: CAS:471-47-6;   DrugBank:DB03940;   KEGG:C01444;   LINCS:LSM-6631
 xref_mesh: MESH:D010072
 xref: PDBeChem:OXM;   PMID:23560609;   PMID:24465604;   Reaxys:1743294
 cyclic_relationship: is_conjugate_acid_of CHEBI:58363


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oxamic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldha lactate dehydrogenase A decreases activity
multiple interactions
ISO Oxamic Acid results in decreased activity of LDHA protein
[Oxamic Acid results in decreased activity of LDHA protein] which results in increased susceptibility to Paclitaxel
CTD PMID:21332213 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19757
      biological role 19757
        biochemical role 19377
          metabolite 19352
            prokaryotic metabolite 18418
              bacterial metabolite 18418
                Escherichia coli metabolite 18307
                  oxamic acid 1
                    oxaloamino group 0
                    oxamoyl group 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19807
      composite particle 19807
        hadron 19807
          baryon 19807
            nucleon 19807
              atomic nucleus 19807
                atom 19807
                  main group element atom 19704
                    p-block element atom 19704
                      carbon group element atom 19626
                        carbon atom 19616
                          organic molecular entity 19616
                            organic group 18725
                              organic divalent group 18716
                                organodiyl group 18716
                                  carbonyl group 18664
                                    carbonyl compound 18664
                                      carboxylic acid 18361
                                        carboacyl group 17481
                                          univalent carboacyl group 17481
                                            carbamoyl group 17297
                                              carboxamide 17297
                                                dicarboxylic acid amide 3133
                                                  dicarboxylic acid monoamide 676
                                                    oxamic acid 1
                                                      oxaloamino group 0
                                                      oxamoyl group 0
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