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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:oxamic acid
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Accession:CHEBI:18058 term browser browse the term
Definition:A dicarboxylic acid monoamide resulting from the formal condensation of one of the carboxy groups of oxalic acid with ammonia.
Synonyms:related_synonym: Formula=C2H3NO3;   Glycine, 2-oxo-;   InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6);   InChIKey=SOWBFZRMHSNYGE-UHFFFAOYSA-N;   Oxalic monoamide;   Oxamate;   SMILES=NC(=O)C(O)=O;   amino(oxo)acetic acid
 alt_id: CHEBI:14708;   CHEBI:25740;   CHEBI:44589;   CHEBI:7818
 xref: CAS:471-47-6;   DrugBank:DB03940;   KEGG:C01444;   LINCS:LSM-6631
 xref_mesh: MESH:D010072
 xref: PDBeChem:OXM;   PMID:23560609;   PMID:24465604;   Reaxys:1743294
 cyclic_relationship: is_conjugate_acid_of CHEBI:58363


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oxamic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldha lactate dehydrogenase A decreases activity
multiple interactions
ISO Oxamic Acid results in decreased activity of LDHA protein
[Oxamic Acid results in decreased activity of LDHA protein] which results in increased susceptibility to Paclitaxel
CTD PMID:21332213 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        biochemical role 19313
          metabolite 19294
            prokaryotic metabolite 18402
              bacterial metabolite 18402
                Escherichia coli metabolite 18283
                  oxamic acid 1
                    oxaloamino group 0
                    oxamoyl group 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic group 18537
                              organic divalent group 18530
                                organodiyl group 18530
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18114
                                        carboacyl group 17372
                                          univalent carboacyl group 17372
                                            carbamoyl group 17158
                                              carboxamide 17158
                                                dicarboxylic acid amide 3108
                                                  dicarboxylic acid monoamide 673
                                                    oxamic acid 1
                                                      oxaloamino group 0
                                                      oxamoyl group 0
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