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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:L-glutamine
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Accession:CHEBI:18050 term browser browse the term
Definition:An optically active form of glutamine having L-configuration.
Synonyms:related_synonym: (2S)-2,5-diamino-5-oxopentanoic acid;   (2S)-2-amino-4-carbamoylbutanoic acid;   (S)-2,5-diamino-5-oxopentanoic acid;   Formula=C5H10N2O3;   GLUTAMINE;   Glutamic acid 5-amide;   Glutamic acid amide;   InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1;   InChIKey=ZDXPYRJPNDTMRX-VKHMYHEASA-N;   L-2-Aminoglutaramic acid;   L-Glutamin;   L-Glutaminsaeure-5-amid;   L-glutamic acid gamma-amide;   Levoglutamide;   Q;   SMILES=N[C@@H](CCC(N)=O)C(O)=O
 alt_id: CHEBI:13110;   CHEBI:21308;   CHEBI:42812;   CHEBI:42814;   CHEBI:42899;   CHEBI:42943;   CHEBI:6227
 xref: Beilstein:1723797;   CAS:56-85-9;   DrugBank:DB00130;   Drug_Central:1311;   ECMDB:ECMDB00641;   Gmelin:3509;   HMDB:HMDB0000641;   KEGG:C00064;   KEGG:D00015;   KNApSAcK:C00001359;   LINCS:LSM-4741
 xref_mesh: MESH:D005973
 xref: MetaCyc:GLN;   PDBeChem:GLN;   PMID:11139387;   PMID:15204730;   PMID:22055478;   PMID:22206385;   PMID:22451274;   PMID:22453904;   PMID:22575040;   PMID:22770225;   PMID:29438107;   Reaxys:1723797;   Wikipedia:Glutamine;   YMDB:YMDB00002
 cyclic_relationship: is_conjugate_acid_of CHEBI:32665;   is_conjugate_base_of CHEBI:32666;   is_enantiomer_of CHEBI:17061;   is_tautomer_of CHEBI:58359


show annotations for term's descendants           Sort by:
L-glutamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase multiple interactions ISO Glutamine inhibits the reaction [Fructose results in increased activity of ADA protein] CTD PMID:31233715 NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO Glutamine deficiency inhibits the reaction [sodium arsenite results in increased expression of CCND1 protein] CTD PMID:33781819 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Glutamine deficiency results in increased expression of DDIT3 mRNA CTD PMID:23123503 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Fgf21 fibroblast growth factor 21 increases expression ISO Glutamine deficiency results in increased expression of FGF21 mRNA CTD PMID:23123503 NCBI chr 7:45,263,314...45,264,914
Ensembl chr 7:45,263,310...45,264,914 		JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked multiple interactions ISO Glutamine inhibits the reaction [Fructose results in decreased expression of G6PD protein] CTD PMID:31233715 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800 		JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 affects abundance EXP GOT1L1 protein affects the abundance of Glutamine CTD PMID:25287256 NCBI chr 8:27,687,487...27,713,872
Ensembl chr 8:27,687,487...27,713,856 		JBrowse link
G Hspa5 heat shock protein 5 increases expression ISO Glutamine deficiency results in increased expression of HSPA5 mRNA CTD PMID:23123503 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO Glutamine deficiency inhibits the reaction [sodium arsenite results in increased expression of PCNA protein] CTD PMID:33781819 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO Glutamine deficiency results in increased expression of PPP1R15A mRNA CTD PMID:23123503 NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692 		JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO Glutamine inhibits the reaction [Fructose results in increased activity of XDH protein] CTD PMID:31233715 NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22194
    role 22179
      application 21760
        pharmaceutical 21174
          drug 21174
            nutraceutical 13734
              L-glutamine 10
                2-methyl-L-glutamine 0
                Ala-Asn-Gln-Ser 0
                Ala-Gln-Pro 0
                Ala-Leu-Thr-Gln 0
                Ala-Met-Gln-Gln 0
                Arg-Asn-Gln-Arg 0
                Arg-Asp-Gln-Ser 0
                Asn-Gln 0
                Asn-Met-Gln-Pro 0
                Asp-Gln-Arg 0
                Asp-Gln-Ser 0
                Asp-Leu-Asp-Gln 0
                Asp-Leu-Leu-Gln 0
                Asp-Phe-Asp-Gln 0
                Cys-Gln-Gln 0
                Cys-Met-Gln 0
                Gln-Asn 0
                Gln-Cys-Cys 0
                Gln-Gln 0
                Gln-Leu 0
                Gln-Leu-Leu-Pro 0
                Gln-Phe 0
                Gln-Phe-Trp-Tyr 0
                Gln-Phe-Tyr 0
                Gln-Ser 0
                Gln-Trp 0
                Gln-Tyr 0
                Gln-Val 0
                Glu-Asp-Gln-Gln 0
                Glu-Gln 0
                Glu-Glu-Gln 0
                Glu-Phe-Gln-Gln 0
                L-glutamine derivative + 0
                L-glutamine residue + 0
                L-glutaminyl group 0
                Leu-Asp-Gln 0
                Leu-Thr-Gln 0
                Lys-Gln 0
                N(2)-L-glutamino group 0
                N(5)-L-glutamino group 0
                chrysopine + 0
                gamma-Glu-Gln 0
                gamma-glutamyl-beta-cyanoalanine 0
                indigoidine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22194
    subatomic particle 22186
      composite particle 22186
        hadron 22186
          baryon 22186
            nucleon 22186
              atomic nucleus 22186
                atom 22186
                  main group element atom 22120
                    main group molecular entity 22120
                      s-block molecular entity 21717
                        hydrogen molecular entity 21634
                          hydrides 20777
                            inorganic hydride 18692
                              pnictogen hydride 18672
                                nitrogen hydride 18540
                                  azane 18447
                                    ammonia 18446
                                      organic amino compound 18446
                                        amino acid 16431
                                          alpha-amino acid 14225
                                            L-alpha-amino acid 13321
                                              glutamine family amino acid 10792
                                                L-glutamine 10
                                                  2-methyl-L-glutamine 0
                                                  Ala-Asn-Gln-Ser 0
                                                  Ala-Gln-Pro 0
                                                  Ala-Leu-Thr-Gln 0
                                                  Ala-Met-Gln-Gln 0
                                                  Arg-Asn-Gln-Arg 0
                                                  Arg-Asp-Gln-Ser 0
                                                  Asn-Gln 0
                                                  Asn-Met-Gln-Pro 0
                                                  Asp-Gln-Arg 0
                                                  Asp-Gln-Ser 0
                                                  Asp-Leu-Asp-Gln 0
                                                  Asp-Leu-Leu-Gln 0
                                                  Asp-Phe-Asp-Gln 0
                                                  Cys-Gln-Gln 0
                                                  Cys-Met-Gln 0
                                                  Gln-Asn 0
                                                  Gln-Cys-Cys 0
                                                  Gln-Gln 0
                                                  Gln-Leu 0
                                                  Gln-Leu-Leu-Pro 0
                                                  Gln-Phe 0
                                                  Gln-Phe-Trp-Tyr 0
                                                  Gln-Phe-Tyr 0
                                                  Gln-Ser 0
                                                  Gln-Trp 0
                                                  Gln-Tyr 0
                                                  Gln-Val 0
                                                  Glu-Asp-Gln-Gln 0
                                                  Glu-Gln 0
                                                  Glu-Glu-Gln 0
                                                  Glu-Phe-Gln-Gln 0
                                                  L-glutamine derivative + 0
                                                  L-glutamine residue + 0
                                                  L-glutaminyl group 0
                                                  Leu-Asp-Gln 0
                                                  Leu-Thr-Gln 0
                                                  Lys-Gln 0
                                                  N(2)-L-glutamino group 0
                                                  N(5)-L-glutamino group 0
                                                  chrysopine + 0
                                                  gamma-Glu-Gln 0
                                                  gamma-glutamyl-beta-cyanoalanine 0
                                                  indigoidine 0
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