Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2,3-dihydroxybenzoic acid
go back to main search page
Accession:CHEBI:18026 term browser browse the term
Definition:A dihydroxybenzoic acid that is benzoic acid substituted by hydroxy groups at positions 2 and 3. It occurs naturally in Phyllanthus acidus and in the aquatic fern Salvinia molesta.
Synonyms:related_synonym: 2,3 DHB;   2,3-DIHYDROXY-BENZOIC ACID;   2-pyrocatechuic acid;   3-hydroxysalicylic acid;   DOBK;   Formula=C7H6O4;   InChI=1S/C7H6O4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,8-9H,(H,10,11);   InChIKey=GLDQAMYCGOIJDV-UHFFFAOYSA-N;   SMILES=OC(=O)c1cccc(O)c1O;   catechol-3-carboxylic acid;   o-pyrocatechuic acid;   pyrocatechuic acid
 alt_id: CHEBI:19320;   CHEBI:41901;   CHEBI:885
 xref: Beilstein:2209117;   CAS:303-38-8;   DrugBank:DB01672;   HMDB:HMDB0000397;   KEGG:C00196;   KNApSAcK:C00002669
 xref_mesh: MESH:C009135
 xref: PDBeChem:DBH;   PMID:17065237;   PMID:24171385;   PMID:3575393;   Reaxys:2209117;   Wikipedia:2\,3-Dihydroxybenzoic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:36654


show annotations for term's descendants           Sort by:
 
2,3-dihydroxybenzoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions ISO 2,3-dihydroxybenzoic acid inhibits the reaction [APP protein modified form binds to APP protein modified form]; Gallic Acid inhibits the reaction [2,3-dihydroxybenzoic acid inhibits the reaction [APP protein modified form binds to APP protein modified form]] CTD PMID:22129351 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases activity
ISO Calcium Chloride inhibits the reaction [2,3-dihydroxybenzoic acid results in decreased activity of MMP2 protein]; ferric chloride inhibits the reaction [2,3-dihydroxybenzoic acid results in decreased activity of MMP2 protein] CTD PMID:10086886 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Prdx3 peroxiredoxin 3 multiple interactions ISO 2,3-dihydroxybenzoic acid promotes the reaction [Kanamycin results in increased expression of PRDX3 protein] CTD PMID:23626763 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        antimicrobial agent 17408
          antimicrobial food preservative 11831
            benzoic acid 4156
              2,3-dihydroxybenzoic acid 3
                2,3-dihydroxybenzoic acid 3-O-beta-D-xyloside 0
                N-(2,3-dihydroxybenzoyl)serine 0
                myxochelin B 0
                vanchrobactin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic acid 18373
                                        aromatic carboxylic acid 11710
                                          benzoic acids 11683
                                            benzoic acid 4156
                                              hydroxybenzoic acid 3560
                                                dihydroxybenzoic acid 62
                                                  2,3-dihydroxybenzoic acid 3
                                                    2,3-dihydroxybenzoic acid 3-O-beta-D-xyloside 0
                                                    N-(2,3-dihydroxybenzoyl)serine 0
                                                    myxochelin B 0
                                                    vanchrobactin 0
paths to the root