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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2,3-dihydroxybenzoic acid
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Accession:CHEBI:18026 term browser browse the term
Definition:A dihydroxybenzoic acid that is benzoic acid substituted by hydroxy groups at positions 2 and 3. It occurs naturally in Phyllanthus acidus and in the aquatic fern Salvinia molesta.
Synonyms:related_synonym: 2,3 DHB;   2,3-DIHYDROXY-BENZOIC ACID;   2-pyrocatechuic acid;   3-hydroxysalicylic acid;   DOBK;   Formula=C7H6O4;   InChI=1S/C7H6O4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,8-9H,(H,10,11);   InChIKey=GLDQAMYCGOIJDV-UHFFFAOYSA-N;   SMILES=OC(=O)c1cccc(O)c1O;   catechol-3-carboxylic acid;   o-pyrocatechuic acid;   pyrocatechuic acid
 alt_id: CHEBI:19320;   CHEBI:41901;   CHEBI:885
 xref: Beilstein:2209117;   CAS:303-38-8;   DrugBank:DB01672;   HMDB:HMDB0000397;   KEGG:C00196;   KNApSAcK:C00002669
 xref_mesh: MESH:C009135
 xref: PDBeChem:DBH;   PMID:17065237;   PMID:24171385;   PMID:3575393;   Reaxys:2209117;   Wikipedia:2\,3-Dihydroxybenzoic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:36654


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2,3-dihydroxybenzoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions ISO 2,3-dihydroxybenzoic acid inhibits the reaction [APP protein modified form binds to APP protein modified form]; Gallic Acid inhibits the reaction [2,3-dihydroxybenzoic acid inhibits the reaction [APP protein modified form binds to APP protein modified form]] CTD PMID:22129351 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases activity		 ISO Calcium Chloride inhibits the reaction [2,3-dihydroxybenzoic acid results in decreased activity of MMP2 protein]; ferric chloride inhibits the reaction [2,3-dihydroxybenzoic acid results in decreased activity of MMP2 protein] CTD PMID:10086886 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Prdx3 peroxiredoxin 3 multiple interactions ISO 2,3-dihydroxybenzoic acid promotes the reaction [Kanamycin results in increased expression of PRDX3 protein] CTD PMID:23626763 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    role 19790
      biological role 19788
        antimicrobial agent 17945
          antimicrobial food preservative 11980
            benzoic acid 4374
              2,3-dihydroxybenzoic acid 3
                2,3-dihydroxybenzoic acid 3-O-beta-D-xyloside 0
                N-(2,3-dihydroxybenzoyl)serine 0
                myxochelin B 0
                vanchrobactin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic group 18905
                              organic divalent group 18887
                                organodiyl group 18887
                                  carbonyl group 18853
                                    carbonyl compound 18853
                                      carboxylic acid 18569
                                        aromatic carboxylic acid 11830
                                          benzoic acids 11805
                                            benzoic acid 4374
                                              hydroxybenzoic acid 3784
                                                dihydroxybenzoic acid 69
                                                  2,3-dihydroxybenzoic acid 3
                                                    2,3-dihydroxybenzoic acid 3-O-beta-D-xyloside 0
                                                    N-(2,3-dihydroxybenzoyl)serine 0
                                                    myxochelin B 0
                                                    vanchrobactin 0
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