Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2,3-dihydroxybenzoic acid
go back to main search page
Accession:CHEBI:18026 term browser browse the term
Definition:A dihydroxybenzoic acid that is benzoic acid substituted by hydroxy groups at positions 2 and 3. It occurs naturally in Phyllanthus acidus and in the aquatic fern Salvinia molesta.
Synonyms:related_synonym: 2,3 DHB;   2,3-DIHYDROXY-BENZOIC ACID;   2-pyrocatechuic acid;   3-hydroxysalicylic acid;   DOBK;   Formula=C7H6O4;   InChI=1S/C7H6O4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,8-9H,(H,10,11);   InChIKey=GLDQAMYCGOIJDV-UHFFFAOYSA-N;   SMILES=OC(=O)c1cccc(O)c1O;   catechol-3-carboxylic acid;   o-pyrocatechuic acid;   pyrocatechuic acid
 alt_id: CHEBI:19320;   CHEBI:41901;   CHEBI:885
 xref: Beilstein:2209117;   CAS:303-38-8;   DrugBank:DB01672;   HMDB:HMDB0000397;   KEGG:C00196;   KNApSAcK:C00002669
 xref_mesh: MESH:C009135
 xref: PDBeChem:DBH;   PMID:17065237;   PMID:24171385;   PMID:3575393;   Reaxys:2209117;   Wikipedia:2\,3-Dihydroxybenzoic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:36654



show annotations for term's descendants           Sort by:
 
2,3-dihydroxybenzoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions ISO 2,3-dihydroxybenzoic acid inhibits the reaction [APP protein modified form binds to APP protein modified form]; Gallic Acid inhibits the reaction [2,3-dihydroxybenzoic acid inhibits the reaction [APP protein modified form binds to APP protein modified form]] CTD PMID:22129351 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases activity
ISO Calcium Chloride inhibits the reaction [2,3-dihydroxybenzoic acid results in decreased activity of MMP2 protein]; ferric chloride inhibits the reaction [2,3-dihydroxybenzoic acid results in decreased activity of MMP2 protein] CTD PMID:10086886 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Prdx3 peroxiredoxin 3 multiple interactions ISO 2,3-dihydroxybenzoic acid promotes the reaction [Kanamycin results in increased expression of PRDX3 protein] CTD PMID:23626763 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    role 20008
      biological role 20007
        antimicrobial agent 17793
          antimicrobial food preservative 11909
            benzoic acid 4328
              2,3-dihydroxybenzoic acid 3
                2,3-dihydroxybenzoic acid 3-O-beta-D-xyloside 0
                N-(2,3-dihydroxybenzoyl)serine 0
                myxochelin B 0
                vanchrobactin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19875
                          organic molecular entity 19875
                            organic group 18961
                              organic divalent group 18947
                                organodiyl group 18947
                                  carbonyl group 18900
                                    carbonyl compound 18900
                                      carboxylic acid 18594
                                        aromatic carboxylic acid 11788
                                          benzoic acids 11763
                                            benzoic acid 4328
                                              hydroxybenzoic acid 3734
                                                dihydroxybenzoic acid 69
                                                  2,3-dihydroxybenzoic acid 3
                                                    2,3-dihydroxybenzoic acid 3-O-beta-D-xyloside 0
                                                    N-(2,3-dihydroxybenzoyl)serine 0
                                                    myxochelin B 0
                                                    vanchrobactin 0
paths to the root