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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:phosphoenolpyruvate
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Accession:CHEBI:18021 term browser browse the term
Definition:A monocarboxylic acid anion resuting from selective deprotonation of the carboxy group of phosphoenolpyruvic acid.
Synonyms:exact_synonym: 2-(phosphonooxy)prop-2-enoate
 related_synonym: 2-(phosphonooxy)-2-propenoate;   2-(phosphonooxy)acrylate;   2-hydroxy-2-propenoate (dihydrogen phosphate) (ester);   2-hydroxy-2-propenoate phosphate (ester);   Formula=C3H4O6P;   InChI=1S/C3H5O6P/c1-2(3(4)5)9-10(6,7)8/h1H2,(H,4,5)(H2,6,7,8)/p-1;   InChIKey=DTBNBXWJWCWCIK-UHFFFAOYSA-M;   O-phosphono-enol-pyruvate;   PEP;   SMILES=OP(O)(=O)OC(=C)C([O-])=O;   phosphoenolpyruvate(1-)
 alt_id: CHEBI:14812;   CHEBI:26054;   CHEBI:8147
 xref: CAS:73-89-2;   KEGG:C00074
 xref_mesh: MESH:D010728
 xref: PDBeChem:PEP;   Reaxys:3946007
 cyclic_relationship: is_conjugate_base_of CHEBI:44897


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phosphoenolpyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions
increases secretion		 ISO Phosphoenolpyruvate inhibits the reaction [Rotenone results in decreased secretion of APP protein modified form]
Phosphoenolpyruvate results in increased secretion of APP protein modified form		 CTD PMID:22906069 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO [amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Phosphoenolpyruvate; PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of Phosphoenolpyruvate] CTD PMID:39172838 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Pkm pyruvate kinase M1/2 multiple interactions
increases metabolic processing		 ISO 3-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate]; 5-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate]; 6-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate]; 7-hydroxyflavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate]; Apigenin inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate]; flavone inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate]; wogonin inhibits the reaction [PKM protein results in increased metabolism of Phosphoenolpyruvate] CTD PMID:25388478 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19917
    role 19887
      biological role 19885
        biochemical role 19569
          metabolite 19577
            fundamental metabolite 14529
              phosphoenolpyruvate 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19917
    subatomic particle 19915
      composite particle 19915
        hadron 19915
          baryon 19915
            nucleon 19915
              atomic nucleus 19915
                atom 19915
                  main group element atom 19855
                    p-block element atom 19855
                      carbon group element atom 19774
                        carbon atom 19790
                          organic molecular entity 19790
                            organic ion 11450
                              organic anion 6851
                                carboxylic acid anion 2501
                                  monocarboxylic acid anion 1605
                                    acrylate 3
                                      phosphoenolpyruvate 3
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