CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 3',4',5-trihydroxy-3,7-dimethoxyflavone
Accession: CHEBI:18010
browse the term
Definition: A dimethoxyflavone that the 3,7-di-O-methyl derivative of quercetin.
Synonyms: exact_synonym: 2-(3,4-dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one
related_synonym: 2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4-benzopyrone; 3,7-Di-O-methylquercetin; 3,7-O-dimethylquercetin; Formula=C17H14O7; InChI=1S/C17H14O7/c1-22-9-6-12(20)14-13(7-9)24-16(17(23-2)15(14)21)8-3-4-10(18)11(19)5-8/h3-7,18-20H,1-2H3; InChIKey=LUJAXSNNYBCFEE-UHFFFAOYSA-N; SMILES=COc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(OC)c2=O
alt_id: CHEBI:11671; CHEBI:11672; CHEBI:1321; CHEBI:19824
xref: CAS:2068-02-2; KEGG:C01265; KNApSAcK:C00004638
xref_mesh: MESH:C549753
xref: MetaCyc:345-TRIHYDROXY-37-DIMETHOXYFLAVONE; PMID:19031255; PMID:2632060; Reaxys:338444
cyclic_relationship: is_conjugate_acid_of CHEBI:77710
G
Ccnb1
cyclin B1
affects phosphorylation increases expression
ISO
5,7,3'-trihydroxy-3,4'-dimethoxyflavone affects the phosphorylation of CCNB1 protein 5,7,3'-trihydroxy-3,4'-dimethoxyflavone results in increased expression of CCNB1 protein
CTD
PMID:21229608
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
G
Cdc25c
cell division cycle 25C
affects phosphorylation
ISO
5,7,3'-trihydroxy-3,4'-dimethoxyflavone affects the phosphorylation of CDC25C protein
CTD
PMID:21229608
NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
G
Cdk1
cyclin-dependent kinase 1
affects phosphorylation
ISO
5,7,3'-trihydroxy-3,4'-dimethoxyflavone affects the phosphorylation of CDK1 protein
CTD
PMID:21229608
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
5,7,3'-trihydroxy-3,4'-dimethoxyflavone results in increased expression of CDKN1A protein
CTD
PMID:21229608
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
G
Foxm1
forkhead box M1
affects phosphorylation
ISO
5,7,3'-trihydroxy-3,4'-dimethoxyflavone affects the phosphorylation of FOXM1 protein
CTD
PMID:21229608
NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684
G
Smpd1
sphingomyelin phosphodiesterase 1
increases activity
ISO
5,7,3'-trihydroxy-3,4'-dimethoxyflavone results in increased activity of SMPD1 protein
CTD
PMID:21229608
NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all