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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3',4',5-trihydroxy-3,7-dimethoxyflavone
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Accession:CHEBI:18010 term browser browse the term
Definition:A dimethoxyflavone that the 3,7-di-O-methyl derivative of quercetin.
Synonyms:exact_synonym: 2-(3,4-dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one
 related_synonym: 2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4-benzopyrone;   3,7-Di-O-methylquercetin;   3,7-O-dimethylquercetin;   Formula=C17H14O7;   InChI=1S/C17H14O7/c1-22-9-6-12(20)14-13(7-9)24-16(17(23-2)15(14)21)8-3-4-10(18)11(19)5-8/h3-7,18-20H,1-2H3;   InChIKey=LUJAXSNNYBCFEE-UHFFFAOYSA-N;   SMILES=COc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(OC)c2=O
 alt_id: CHEBI:11671;   CHEBI:11672;   CHEBI:1321;   CHEBI:19824
 xref: CAS:2068-02-2;   KEGG:C01265;   KNApSAcK:C00004638
 xref_mesh: MESH:C549753
 xref: MetaCyc:345-TRIHYDROXY-37-DIMETHOXYFLAVONE;   PMID:19031255;   PMID:2632060;   Reaxys:338444
 cyclic_relationship: is_conjugate_acid_of CHEBI:77710


show annotations for term's descendants           Sort by:
 
3',4',5-trihydroxy-3,7-dimethoxyflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnb1 cyclin B1 affects phosphorylation
increases expression
ISO 5,7,3'-trihydroxy-3,4'-dimethoxyflavone affects the phosphorylation of CCNB1 protein
5,7,3'-trihydroxy-3,4'-dimethoxyflavone results in increased expression of CCNB1 protein
CTD PMID:21229608 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Cdc25c cell division cycle 25C affects phosphorylation ISO 5,7,3'-trihydroxy-3,4'-dimethoxyflavone affects the phosphorylation of CDC25C protein CTD PMID:21229608 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdk1 cyclin-dependent kinase 1 affects phosphorylation ISO 5,7,3'-trihydroxy-3,4'-dimethoxyflavone affects the phosphorylation of CDK1 protein CTD PMID:21229608 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO 5,7,3'-trihydroxy-3,4'-dimethoxyflavone results in increased expression of CDKN1A protein CTD PMID:21229608 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Foxm1 forkhead box M1 affects phosphorylation ISO 5,7,3'-trihydroxy-3,4'-dimethoxyflavone affects the phosphorylation of FOXM1 protein CTD PMID:21229608 NCBI chr 4:161,685,236...161,697,633
Ensembl chr 4:161,685,258...161,696,305
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 increases activity ISO 5,7,3'-trihydroxy-3,4'-dimethoxyflavone results in increased activity of SMPD1 protein CTD PMID:21229608 NCBI chr 1:170,383,682...170,387,525
Ensembl chr 1:170,383,682...170,387,524
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      chemical role 19250
        antioxidant 14211
          quercetin 3999
            3',4',5-trihydroxy-3,7-dimethoxyflavone 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic molecule 19488
                              organic cyclic compound 19285
                                organic heterocyclic compound 18410
                                  oxacycle 17185
                                    benzopyran 10135
                                      1-benzopyran 9851
                                        flavonoid 6374
                                          flavones 4166
                                            hydroxyflavone 4154
                                              flavonols 4070
                                                7-hydroxyflavonol 4049
                                                  quercetin 3999
                                                    3',4',5-trihydroxy-3,7-dimethoxyflavone 6
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