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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3',4',5-trihydroxy-3,7-dimethoxyflavone
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Accession:CHEBI:18010 term browser browse the term
Definition:A dimethoxyflavone that the 3,7-di-O-methyl derivative of quercetin.
Synonyms:exact_synonym: 2-(3,4-dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one
 related_synonym: 2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4-benzopyrone;   3,7-Di-O-methylquercetin;   3,7-O-dimethylquercetin;   Formula=C17H14O7;   InChI=1S/C17H14O7/c1-22-9-6-12(20)14-13(7-9)24-16(17(23-2)15(14)21)8-3-4-10(18)11(19)5-8/h3-7,18-20H,1-2H3;   InChIKey=LUJAXSNNYBCFEE-UHFFFAOYSA-N;   SMILES=COc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(OC)c2=O
 alt_id: CHEBI:11671;   CHEBI:11672;   CHEBI:1321;   CHEBI:19824
 xref: CAS:2068-02-2;   KEGG:C01265;   KNApSAcK:C00004638
 xref_mesh: MESH:C549753
 xref: MetaCyc:345-TRIHYDROXY-37-DIMETHOXYFLAVONE;   PMID:19031255;   PMID:2632060;   Reaxys:338444
 cyclic_relationship: is_conjugate_acid_of CHEBI:77710


show annotations for term's descendants           Sort by:
3',4',5-trihydroxy-3,7-dimethoxyflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnb1 cyclin B1 affects phosphorylation
increases expression		 ISO 5,7,3'-trihydroxy-3,4'-dimethoxyflavone affects the phosphorylation of CCNB1 protein
5,7,3'-trihydroxy-3,4'-dimethoxyflavone results in increased expression of CCNB1 protein		 CTD PMID:21229608 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Cdc25c cell division cycle 25C affects phosphorylation ISO 5,7,3'-trihydroxy-3,4'-dimethoxyflavone affects the phosphorylation of CDC25C protein CTD PMID:21229608 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 affects phosphorylation ISO 5,7,3'-trihydroxy-3,4'-dimethoxyflavone affects the phosphorylation of CDK1 protein CTD PMID:21229608 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO 5,7,3'-trihydroxy-3,4'-dimethoxyflavone results in increased expression of CDKN1A protein CTD PMID:21229608 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Foxm1 forkhead box M1 affects phosphorylation ISO 5,7,3'-trihydroxy-3,4'-dimethoxyflavone affects the phosphorylation of FOXM1 protein CTD PMID:21229608 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 increases activity ISO 5,7,3'-trihydroxy-3,4'-dimethoxyflavone results in increased activity of SMPD1 protein CTD PMID:21229608 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      chemical role 19422
        antioxidant 16120
          quercetin 4320
            3',4',5-trihydroxy-3,7-dimethoxyflavone 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            organic molecule 19658
                              organic cyclic compound 19471
                                organic heterocyclic compound 18862
                                  oxacycle 17819
                                    benzopyran 11950
                                      1-benzopyran 11702
                                        flavonoid 7190
                                          anthoxanthin 4536
                                            flavones 4536
                                              hydroxyflavone 4517
                                                flavonols 4408
                                                  7-hydroxyflavonol 4383
                                                    quercetin 4320
                                                      3',4',5-trihydroxy-3,7-dimethoxyflavone 6
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