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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dinitrogen
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Accession:CHEBI:17997 term browser browse the term
Definition:An elemental molecule consisting of two trivalently-bonded nitrogen atoms.
Synonyms:related_synonym: Formula=N2;   InChI=1S/N2/c1-2;   InChIKey=IJGRMHOSHXDMSA-UHFFFAOYSA-N;   N#N;   N2;   Nitrogen;   SMILES=N#N;   molecular nitrogen
 alt_id: CHEBI:13388;   CHEBI:14660;   CHEBI:25365;   CHEBI:43128;   CHEBI:7593
 xref: CAS:7727-37-9;   Drug_Central:4251;   Gmelin:150;   HMDB:HMDB0001371;   KEGG:C00697;   KEGG:D00083
 xref_mesh: MESH:D009584
 xref: MetaCyc:NITROGEN-MOLECULE;   PDBeChem:HDZ;   PMID:18334638;   PMID:22237545;   Reaxys:15940095;   Wikipedia:Nitrogen
 cyclic_relationship: is_conjugate_base_of CHEBI:30102


show annotations for term's descendants           Sort by:
dinitrogen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg13 autophagy related 13 multiple interactions ISO ATG13 protein inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]; ATG13 protein promotes the reaction [bafilomycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]]; Nitrogen deficiency inhibits the reaction [ATG13 protein results in increased expression of ULK1 protein]; Nitrogen deficiency promotes the reaction [ATG13 protein results in decreased expression of SQSTM1 protein] CTD PMID:27629431 NCBI chr 2:91,504,957...91,540,947
Ensembl chr 2:91,504,963...91,540,921 		JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase decreases expression ISO Nitrogen deficiency results in decreased expression of ATG4B protein CTD PMID:27629431 NCBI chr 1:93,682,627...93,717,328
Ensembl chr 1:93,679,222...93,718,332 		JBrowse link
G Atg7 autophagy related 7 multiple interactions ISO ATG7 protein inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]; ATG7 protein promotes the reaction [bafilomycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]] CTD PMID:27629431 NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of CCL2 protein CTD PMID:30711708 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of CCL5 protein CTD PMID:30711708 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344 		JBrowse link
G Cdk4 cyclin dependent kinase 4 multiple interactions ISO [Nanotubes, Carbon co-treated with Nitrogen] results in increased expression of CDK4 protein CTD PMID:25797581 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789 		JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of CSF2 protein CTD PMID:30711708 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493 		JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of CSF3 protein CTD PMID:30711708 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of CXCL1 protein CTD PMID:30711708 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of CXCL8 protein CTD PMID:30711708 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of CXCL1 protein CTD PMID:30711708 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459 		JBrowse link
G Grk1 G protein-coupled receptor kinase 1 multiple interactions EXP [Nitrogen co-treated with Iodoacetic Acid] results in increased expression of GRK1 mRNA; Octreotide affects the reaction [SSTR1 protein affects the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of GRK1 mRNA]]; Octreotide inhibits the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of GRK1 mRNA]; SSTR1 protein affects the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of GRK1 mRNA] CTD PMID:18624922 NCBI chr 8:13,455,081...13,471,951
Ensembl chr 8:13,455,081...13,471,951 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of IL6 protein CTD PMID:30711708 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased phosphorylation of MAPK1 protein CTD PMID:30711708 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased phosphorylation of MAPK3 protein CTD PMID:30711708 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of MIF protein CTD PMID:30711708 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
G Rgs1 regulator of G-protein signaling 1 multiple interactions EXP [Nitrogen co-treated with Iodoacetic Acid] results in increased expression of RGS1 mRNA; Octreotide inhibits the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of RGS1 mRNA]; SSTR1 protein affects the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of RGS1 mRNA] CTD PMID:18624922 NCBI chr 1:144,120,407...144,124,862
Ensembl chr 1:144,118,034...144,124,980 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of SERPINE1 protein CTD PMID:30711708 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Sqstm1 sequestosome 1 decreases expression
multiple interactions		 ISO Nitrogen deficiency results in decreased expression of SQSTM1 protein
bafilomycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of SQSTM1 protein]; Nitrogen deficiency promotes the reaction [ATG13 protein results in decreased expression of SQSTM1 protein]		 CTD PMID:27629431 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654 		JBrowse link
G Sstr1 somatostatin receptor 1 multiple interactions EXP Octreotide affects the reaction [SSTR1 protein affects the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of GRK1 mRNA]]; SSTR1 protein affects the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of GRK1 mRNA]; SSTR1 protein affects the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of RGS1 mRNA] CTD PMID:18624922 NCBI chr12:58,258,524...58,262,822
Ensembl chr12:58,258,558...58,260,673 		JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO Nitrogen inhibits the reaction [myricetin results in decreased activity of TXNRD1 protein modified form]; Nitrogen inhibits the reaction [Quercetin results in decreased activity of TXNRD1 protein modified form] CTD PMID:16618767 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546 		JBrowse link
G Ulk1 unc-51 like kinase 1 increases expression
multiple interactions		 ISO Nitrogen deficiency results in increased expression of ULK1 mRNA
Antimycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]; ATG13 protein inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]; ATG13 protein promotes the reaction [bafilomycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]]; ATG7 protein inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]; ATG7 protein promotes the reaction [bafilomycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]]; bafilomycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]; Nitrogen deficiency inhibits the reaction [Antimycin A results in increased expression of ULK1 protein]; Nitrogen deficiency inhibits the reaction [ATG13 protein results in increased expression of ULK1 protein]; Nitrogen deficiency results in decreased expression of and results in decreased phosphorylation of and results in increased cleavage of and affects the localization of ULK1 protein		 CTD PMID:27629431 NCBI chr 5:110,932,355...110,957,991
Ensembl chr 5:110,932,354...110,957,963 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    chemical entity 22208
      molecular entity 22169
        main group molecular entity 22104
          gas molecular entity 19926
            dinitrogen 22
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      pnictogen 20333
                        pnictogen molecular entity 20333
                          elemental pnictogen 97
                            elemental nitrogen 22
                              diatomic nitrogen 22
                                dinitrogen 22
paths to the root