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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dinitrogen
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Accession:CHEBI:17997 term browser browse the term
Definition:An elemental molecule consisting of two trivalently-bonded nitrogen atoms.
Synonyms:related_synonym: Formula=N2;   InChI=1S/N2/c1-2;   InChIKey=IJGRMHOSHXDMSA-UHFFFAOYSA-N;   N#N;   N2;   Nitrogen;   SMILES=N#N;   molecular nitrogen
 alt_id: CHEBI:13388;   CHEBI:14660;   CHEBI:25365;   CHEBI:43128;   CHEBI:7593
 xref: CAS:7727-37-9;   Drug_Central:4251;   Gmelin:150;   HMDB:HMDB0001371;   KEGG:C00697;   KEGG:D00083
 xref_mesh: MESH:D009584
 xref: MetaCyc:NITROGEN-MOLECULE;   PDBeChem:HDZ;   PMID:18334638;   PMID:22237545;   Reaxys:15940095;   Wikipedia:Nitrogen
 cyclic_relationship: is_conjugate_base_of CHEBI:30102


show annotations for term's descendants           Sort by:
dinitrogen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg13 autophagy related 13 multiple interactions ISO ATG13 protein inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]; ATG13 protein promotes the reaction [bafilomycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]]; Nitrogen deficiency inhibits the reaction [ATG13 protein results in increased expression of ULK1 protein]; Nitrogen deficiency promotes the reaction [ATG13 protein results in decreased expression of SQSTM1 protein] CTD PMID:27629431 NCBI chr 3:98,102,831...98,136,741
Ensembl chr 3:77,645,790...77,681,043 		JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase decreases expression ISO Nitrogen deficiency results in decreased expression of ATG4B protein CTD PMID:27629431 NCBI chr 9:101,729,772...101,761,456
Ensembl chr 9:94,282,509...94,314,103 		JBrowse link
G Atg7 autophagy related 7 multiple interactions ISO ATG7 protein inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]; ATG7 protein promotes the reaction [bafilomycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]] CTD PMID:27629431 NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of CCL2 protein CTD PMID:30711708 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of CCL5 protein CTD PMID:30711708 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions ISO [Nanotubes, Carbon co-treated with Nitrogen] results in increased expression of CDK4 protein CTD PMID:25797581 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of CSF2 protein CTD PMID:30711708 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of CSF3 protein CTD PMID:30711708 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of CXCL1 protein CTD PMID:30711708 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of CXCL1 protein CTD PMID:30711708 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Grk1 G protein-coupled receptor kinase 1 multiple interactions ISO [Nitrogen co-treated with Iodoacetic Acid] results in increased expression of GRK1 mRNA; Octreotide affects the reaction [SSTR1 protein affects the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of GRK1 mRNA]]; Octreotide inhibits the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of GRK1 mRNA]; SSTR1 protein affects the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of GRK1 mRNA] CTD PMID:18624922 NCBI chr16:82,821,184...82,837,971
Ensembl chr16:76,123,842...76,135,792 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of IL6 protein CTD PMID:30711708 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased phosphorylation of MAPK1 protein CTD PMID:30711708 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased phosphorylation of MAPK3 protein CTD PMID:30711708 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mif macrophage migration inhibitory factor multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of MIF protein CTD PMID:30711708 NCBI chr20:12,767,138...12,791,222
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504 		JBrowse link
G Rgs1 regulator of G-protein signaling 1 multiple interactions ISO [Nitrogen co-treated with Iodoacetic Acid] results in increased expression of RGS1 mRNA; Octreotide inhibits the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of RGS1 mRNA]; SSTR1 protein affects the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of RGS1 mRNA] CTD PMID:18624922 NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of SERPINE1 protein CTD PMID:30711708 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
decreases expression		 ISO bafilomycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of SQSTM1 protein]; Nitrogen deficiency promotes the reaction [ATG13 protein results in decreased expression of SQSTM1 protein] CTD PMID:27629431 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Sstr1 somatostatin receptor 1 multiple interactions ISO Octreotide affects the reaction [SSTR1 protein affects the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of GRK1 mRNA]]; SSTR1 protein affects the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of GRK1 mRNA]; SSTR1 protein affects the reaction [[Nitrogen co-treated with Iodoacetic Acid] results in increased expression of RGS1 mRNA] CTD PMID:18624922 NCBI chr 6:81,567,237...81,571,759
Ensembl chr 6:75,832,530...75,836,802 		JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions EXP Nitrogen inhibits the reaction [myricetin results in decreased activity of TXNRD1 protein modified form]; Nitrogen inhibits the reaction [Quercetin results in decreased activity of TXNRD1 protein modified form] CTD PMID:16618767 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions
increases expression		 ISO Antimycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]; ATG13 protein inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]; ATG13 protein promotes the reaction [bafilomycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]]; ATG7 protein inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]; ATG7 protein promotes the reaction [bafilomycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]]; bafilomycin A inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein]; Nitrogen deficiency inhibits the reaction [Antimycin A results in increased expression of ULK1 protein]; Nitrogen deficiency inhibits the reaction [ATG13 protein results in increased expression of ULK1 protein]; Nitrogen deficiency results in decreased expression of and results in decreased phosphorylation of and results in increased cleavage of and affects the localization of ULK1 protein
Nitrogen deficiency results in increased expression of ULK1 mRNA		 CTD PMID:27629431 NCBI chr12:51,511,492...51,537,746
Ensembl chr12:45,851,710...45,877,966 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    chemical entity 19885
      molecular entity 19884
        main group molecular entity 19824
          gas molecular entity 18470
            dinitrogen 21
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    p-block element atom 19824
                      pnictogen 19080
                        pnictogen molecular entity 19080
                          elemental pnictogen 97
                            elemental nitrogen 21
                              diatomic nitrogen 21
                                dinitrogen 21
paths to the root