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ONTOLOGY REPORT - ANNOTATIONS


Term:(+)-taxifolin
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Accession:CHEBI:17948 term browser browse the term
Definition:A taxifolin that has (2R,3R)-configuration.
Synonyms:exact_synonym: (2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydro-4H-chromen-4-one
 related_synonym: (2R,3R)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one;   (2R,3R)-dihydroquercetin;   (2R-trans)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4-benzopyrone;   Dihydroquercetin;   Formula=C15H12O7;   InChI=1S/C15H12O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,14-19,21H/t14-,15+/m0/s1;   InChIKey=CXQWRCVTCMQVQX-LSDHHAIUSA-N;   SMILES=O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c1ccc(O)c(O)c1;   trans-Dihydroquercetin
 alt_id: CHEBI:15206;   CHEBI:23764;   CHEBI:42225;   CHEBI:9415
 xref: Beilstein:93548 "Beilstein";   CAS:480-18-2 "ChemIDplus";   CAS:480-18-2 "KEGG COMPOUND";   DrugBank:DB02224;   KEGG:C01617;   KNApSAcK:C00000677;   LINCS:LSM-5990
 xref_mesh: MESH:C003377
 xref: PDBeChem:DQH;   Wikipedia:Taxifolin
 cyclic_relationship: is_conjugate_acid_of CHEBI:58329;   is_enantiomer_of CHEBI:41963


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(+)-taxifolin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCC1 ATP binding cassette subfamily C member 1 JBrowse link 16 15,949,616 16,143,062 RGD:6480464
G AFP alpha fetoprotein JBrowse link 4 73,436,221 73,456,174 RGD:6480464
G AGT angiotensinogen JBrowse link 1 230,702,523 230,714,122 RGD:6480464
G AHR aryl hydrocarbon receptor JBrowse link 7 17,298,652 17,346,147 RGD:6480464
G APOA1 apolipoprotein A1 JBrowse link 11 116,835,751 116,837,950 RGD:6480464
G APOB apolipoprotein B JBrowse link 2 21,001,429 21,044,073 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CASP9 caspase 9 JBrowse link 1 15,491,401 15,524,912 RGD:6480464
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:6480464
G CCNA1 cyclin A1 JBrowse link 13 36,430,488 36,442,882 RGD:6480464
G CDC25A cell division cycle 25A JBrowse link 3 48,157,146 48,188,417 RGD:6480464
G CPT1A carnitine palmitoyltransferase 1A JBrowse link 11 68,754,620 68,844,410 RGD:6480464
G CYCS cytochrome c, somatic JBrowse link 7 25,118,656 25,125,260 RGD:6480464
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 JBrowse link 15 74,719,542 74,725,528 RGD:6480464
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 JBrowse link 10 133,527,363 133,539,123 RGD:6480464
G DCC DCC netrin 1 receptor JBrowse link 18 52,340,172 53,535,899 RGD:6480464
G EGF epidermal growth factor JBrowse link 4 109,912,883 110,013,766 RGD:6480464
G FGF18 fibroblast growth factor 18 JBrowse link 5 171,419,647 171,457,626 RGD:6480464
G FGF3 fibroblast growth factor 3 JBrowse link 11 69,809,968 69,819,416 RGD:6480464
G GAS6 growth arrest specific 6 JBrowse link 13 113,820,549 113,864,076 RGD:6480464
G GDF15 growth differentiation factor 15 JBrowse link 19 18,382,170 18,389,176 RGD:6480464
G GSTM1 glutathione S-transferase mu 1 JBrowse link 1 109,687,817 109,693,745 RGD:6480464
G HMOX1 heme oxygenase 1 JBrowse link 22 35,381,096 35,394,207 RGD:6480464
G ICAM1 intercellular adhesion molecule 1 JBrowse link 19 10,271,120 10,286,615 RGD:6480464
G IFNG interferon gamma JBrowse link 12 68,154,768 68,159,740 RGD:6480464
G JUN Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 1 58,780,791 58,784,047 RGD:6480464
G MAPK8 mitogen-activated protein kinase 8 JBrowse link 10 48,306,639 48,439,360 RGD:6480464
G MTTP microsomal triglyceride transfer protein JBrowse link 4 99,564,078 99,623,997 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:6480464
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 16 69,709,401 69,726,560 RGD:6480464
G PDGFB platelet derived growth factor subunit B JBrowse link 22 39,223,359 39,244,982 RGD:6480464
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 186,671,791 186,680,423 RGD:6480464
G RASA1 RAS p21 protein activator 1 JBrowse link 5 87,267,845 87,391,926 RGD:6480464
G STAT1 signal transducer and activator of transcription 1 JBrowse link 2 190,968,989 191,014,250 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G TRAF3 TNF receptor associated factor 3 JBrowse link 14 102,777,449 102,911,500 RGD:6480464
G TXNRD1 thioredoxin reductase 1 JBrowse link 12 104,215,779 104,350,307 RGD:6480464
G UCP1 uncoupling protein 1 JBrowse link 4 140,555,770 140,568,961 RGD:6480464
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 2 233,760,270 233,773,300 RGD:6480464
G XDH xanthine dehydrogenase JBrowse link 2 31,334,320 31,414,777 RGD:6480464
G XPA XPA, DNA damage recognition and repair factor JBrowse link 9 97,654,398 97,697,409 RGD:6480464
G XRCC4 X-ray repair cross complementing 4 JBrowse link 5 83,077,409 83,370,333 RGD:6480464
astilbin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKR1C1 aldo-keto reductase family 1 member C1 JBrowse link 10 4,963,415 4,983,283 RGD:6480464
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6480464
G BAX BCL2 associated X, apoptosis regulator JBrowse link 19 48,954,825 48,961,798 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CASP9 caspase 9 JBrowse link 1 15,491,401 15,524,912 RGD:6480464
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:6480464
G GCLC glutamate-cysteine ligase catalytic subunit JBrowse link 6 53,497,341 53,545,101 RGD:6480464
G GCLM glutamate-cysteine ligase modifier subunit JBrowse link 1 93,885,199 93,910,370 RGD:6480464
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:6480464
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:6480464
G NFKBIA NFKB inhibitor alpha JBrowse link 14 35,401,513 35,404,749 RGD:6480464
G NOS2 nitric oxide synthase 2 JBrowse link 17 27,756,766 27,800,529 RGD:6480464
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 16 69,709,401 69,726,560 RGD:6480464
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 226,360,691 226,408,093 RGD:6480464
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 186,671,791 186,680,423 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G TP53 tumor protein p53 JBrowse link 17 7,668,402 7,687,550 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23754
    role 23643
      biological role 23606
        biochemical role 22954
          metabolite 22846
            (+)-taxifolin 57
              (+)-taxifolin 3-O-acetate 0
              (+)-taxifolin 3-O-alpha-D-arabinopyranoside 0
              (+)-taxifolin 3-O-alpha-L-arabinofuranoside 0
              (+)-taxifolin 3-O-alpha-L-arabinopyranoside 0
              (+)-taxifolin 3-O-beta-D-arabinopyranoside 0
              (+)-taxifolin 3-O-beta-D-xylopyranoside 0
              6-methoxytaxifolin 0
              astilbin 22
Path 2
Term Annotations click to browse term
  CHEBI ontology 23754
    subatomic particle 23703
      composite particle 23703
        hadron 23703
          baryon 23703
            nucleon 23703
              atomic nucleus 23703
                atom 23703
                  main group element atom 23522
                    p-block element atom 23522
                      carbon group element atom 23232
                        carbon atom 23208
                          organic molecular entity 23208
                            organic molecule 23069
                              organic cyclic compound 22083
                                organic heterocyclic compound 20724
                                  oxacycle 18965
                                    benzopyran 9911
                                      1-benzopyran 9590
                                        flavonoid 6698
                                          flavones 4314
                                            hydroxyflavone 4303
                                              flavonols 4233
                                                7-hydroxyflavonol 4208
                                                  quercetin 4157
                                                    taxifolin 57
                                                      (+)-taxifolin 57
                                                        (+)-taxifolin 3-O-acetate 0
                                                        (+)-taxifolin 3-O-alpha-D-arabinopyranoside 0
                                                        (+)-taxifolin 3-O-alpha-L-arabinofuranoside 0
                                                        (+)-taxifolin 3-O-alpha-L-arabinopyranoside 0
                                                        (+)-taxifolin 3-O-beta-D-arabinopyranoside 0
                                                        (+)-taxifolin 3-O-beta-D-xylopyranoside 0
                                                        6-methoxytaxifolin 0
                                                        astilbin 22
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.