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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N-hydroxy-2-acetamidofluorene
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Accession:CHEBI:17931 term browser browse the term
Definition:A 2-acetamidofluorene that has formula C15H13NO2.
Synonyms:exact_synonym: N-(9H-fluoren-2-yl)-N-hydroxyacetamide
 related_synonym: 2-(N-Acetylhydroxylamino)fluorene;   2-(N-Hydroxyacetamido)fluorene;   Fluorenyl-2-acethydroxamic acid;   Formula=C15H13NO2;   Hydroxyacetylaminofluorene;   InChI=1S/C15H13NO2/c1-10(17)16(18)13-6-7-15-12(9-13)8-11-4-2-3-5-14(11)15/h2-7,9,18H,8H2,1H3;   InChIKey=SOKUIEGXJHVFDV-UHFFFAOYSA-N;   N-Fluoren-2-ylacetohydroxamic acid;   N-Hydroxy-N-acetyl-2-aminofluorene;   SMILES=CC(=O)N(O)c1ccc-2c(Cc3ccccc-23)c1
 alt_id: CHEBI:12511;   CHEBI:12599;   CHEBI:21734;   CHEBI:7294
 xref: CAS:53-95-2;   KEGG:C03954
 xref_mesh: MESH:D006881


show annotations for term's descendants           Sort by:
N-hydroxy-2-acetamidofluorene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, sub-family B member 1B increases expression EXP Hydroxyacetylaminofluorene results in increased expression of ABCB1B mRNA; Hydroxyacetylaminofluorene results in increased expression of ABCB1B protein CTD PMID:22084566 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Nat1 N-acetyltransferase 1 decreases activity ISO Hydroxyacetylaminofluorene results in decreased activity of NAT1 protein CTD PMID:19842618 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Nat2 N-acetyltransferase 2 decreases activity ISO Hydroxyacetylaminofluorene results in decreased activity of NAT2 protein CTD PMID:19842618 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases sulfation ISO SULT2A1 protein results in increased sulfation of Hydroxyacetylaminofluorene CTD PMID:10752640 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Tp53 tumor protein p53 increases expression EXP Hydroxyacetylaminofluorene results in increased expression of TP53 protein CTD PMID:9163691 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      biological role 19785
        xenobiotic 18731
          fluorenes 429
            2-acetamidofluorenes 422
              N-hydroxy-2-acetamidofluorene 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    main group molecular entity 19759
                      s-block molecular entity 19628
                        hydrogen molecular entity 19614
                          hydrides 19087
                            organic hydride 18656
                              organic fundamental parent 18656
                                hydrocarbon 18396
                                  cyclic hydrocarbon 17214
                                    arene 17209
                                      polycyclic arene 17023
                                        ortho-fused polycyclic arene 9816
                                          fluorene 555
                                            fluorenes 429
                                              2-acetamidofluorenes 422
                                                N-hydroxy-2-acetamidofluorene 5
paths to the root