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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:7alpha-hydroxycholest-4-en-3-one
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Accession:CHEBI:17899 term browser browse the term
Definition:A cholestanoid consisting of a cholesterol core having an oxo group at the 3-position, a C=C bond at the 4,5-position and an alpha-hydroxy group at the 7-position.
Synonyms:related_synonym: 7alpha-Hydroxy-4-cholesten-3-one;   Cholest-4-en-7alpha-ol-3-one;   Formula=C27H44O2;   InChI=1S/C27H44O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h15,17-18,21-25,29H,6-14,16H2,1-5H3/t18-,21-,22+,23+,24-,25+,26+,27-/m1/s1;   InChIKey=IOIZWEJGGCZDOL-RQDYSCIWSA-N;   SMILES=[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)CC4=CC(=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C
 alt_id: CHEBI:12262;   CHEBI:20800;   CHEBI:2292;   CHEBI:58317
 xref: CAS:3862-25-7;   KEGG:C05455;   LIPID_MAPS_instance:LMST04030123
 xref_mesh: MESH:C002656


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7alpha-hydroxycholest-4-en-3-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1d1 aldo-keto reductase family 1, member D1 multiple interactions ISO [AKR1D1 protein co-treated with NADP] results in increased reduction of 7 alpha-hydroxy-4-cholesten-3-one; AKR1D1 gene mutant form inhibits the reaction [AKR1D1 protein results in increased metabolism of 7 alpha-hydroxy-4-cholesten-3-one] CTD PMID:21185810 PMID:25500266 NCBI chr 4:65,110,706...65,143,930
Ensembl chr 4:65,110,746...65,143,941
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Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      group 19722
        organic group 18527
          3-oxo-Delta(4)-steroid group 7938
            3-oxo-Delta(4) steroid 7938
              7alpha-hydroxycholest-4-en-3-one 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic group 18527
                              organic divalent group 18520
                                organodiyl group 18520
                                  carbonyl group 18427
                                    carbonyl compound 18427
                                      ketone 16171
                                        oxo steroid 9279
                                          3-oxo steroid 8809
                                            3-oxo-Delta(4) steroid 7938
                                              7alpha-hydroxycholest-4-en-3-one 1
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