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ONTOLOGY REPORT - ANNOTATIONS


Term:all-trans-retinal
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Accession:CHEBI:17898 term browser browse the term
Definition:A retinal in which all four exocyclic double bonds have E- (trans-) geometry.
Synonyms:exact_synonym: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenal
 related_synonym: Formula=C20H28O;   InChI=1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6+,12-11+,16-8+,17-13+;   InChIKey=NCYCYZXNIZJOKI-OVSJKPMPSA-N;   Retinal;   Retinene;   SMILES=[H]C(=O)\\C=C(C)\\C=C\\C=C(C)\\C=C\\C1=C(C)CCCC1(C)C;   Vitamin A aldehyde;   all-trans-Retinene;   all-trans-Vitamin A aldehyde;   all-trans-retinaldehyde;   retinaldehyde
 alt_id: CHEBI:12776;   CHEBI:22348;   CHEBI:8814
 xref: CAS:116-31-4 "ChemIDplus";   CAS:116-31-4 "KEGG COMPOUND";   CAS:116-31-4 "NIST Chemistry WebBook";   HMDB:HMDB0001358;   KEGG:C00376;   LIPID_MAPS_instance:LMPR01090002 "LIPID MAPS"
 xref_mesh: MESH:D012172
 xref: MetaCyc:RETINAL;   PDBeChem:RET;   PMID:12168520 "Europe PMC";   PMID:15500295 "Europe PMC";   PMID:15686550 "Europe PMC";   PMID:15724104 "Europe PMC";   PMID:16054134 "Europe PMC";   PMID:16128572 "Europe PMC";   PMID:17326003 "Europe PMC";   PMID:21447403 "Europe PMC";   PMID:21995425 "Europe PMC";   PMID:22162152 "Europe PMC";   PMID:22198730 "Europe PMC";   PMID:22220722 "Europe PMC";   PMID:22417174 "Europe PMC";   PMID:22428905 "Europe PMC";   PMID:22431612 "Europe PMC";   PMID:22515697 "Europe PMC";   PMID:22529810 "Europe PMC";   PMID:22559266 "Europe PMC";   PMID:22621924 "Europe PMC";   PMID:22841964 "Europe PMC";   PMID:22879987 "Europe PMC";   Wikipedia:Retinal


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all-trans-retinal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca4 ATP binding cassette subfamily A member 4 JBrowse link 2 225,645,539 225,783,288 RGD:6480464
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide JBrowse link 2 243,702,035 243,720,063 RGD:6480464
G Akr1b1 aldo-keto reductase family 1 member B JBrowse link 4 61,706,866 61,720,959 RGD:6480464
G Akr1b10 aldo-keto reductase family 1 member B10 JBrowse link 4 61,813,265 61,830,371 RGD:6480464
G Akr1b7 aldo-keto reductase family 1, member B7 JBrowse link 4 61,850,256 61,879,733 RGD:6480464
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 JBrowse link 1 238,222,689 238,264,381 RGD:6480464
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 JBrowse link 8 77,640,234 77,719,488 RGD:6480464
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 JBrowse link 1 127,302,920 127,337,828 RGD:6480464
G Aldh2 aldehyde dehydrogenase 2 family member JBrowse link 12 40,466,418 40,498,813 RGD:6480464
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 JBrowse link 10 47,490,168 47,499,855 RGD:6480464
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:6480464
G Atf4 activating transcription factor 4 JBrowse link 7 121,480,723 121,482,781 RGD:6480464
G Btc betacellulin JBrowse link 14 18,231,854 18,270,621 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 JBrowse link 1 256,382,861 256,386,729 RGD:6480464
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:6480464
G Dhrs4 dehydrogenase/reductase 4 JBrowse link 15 34,155,043 34,167,073 RGD:6480464
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:6480464
G Hbegf heparin-binding EGF-like growth factor JBrowse link 18 29,330,302 29,340,185 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:6480464
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:6480464
G Rbp1 retinol binding protein 1 JBrowse link 8 106,449,321 106,470,842 RGD:6480464
G Rdh10 retinol dehydrogenase 10 JBrowse link 5 2,605,265 2,631,905 RGD:6480464
G Rdh12 retinol dehydrogenase 12 JBrowse link 6 102,392,828 102,405,750 RGD:6480464
G Rdh5 retinol dehydrogenase 5 JBrowse link 7 3,335,681 3,342,573 RGD:6480464
G Rpe65 retinoid isomerohydrolase RPE65 JBrowse link 2 266,141,581 266,169,197 RGD:6480464
G Sdr16c5 short chain dehydrogenase/reductase family 16C, member 5 JBrowse link 5 16,904,926 16,930,111 RGD:6480464
all-trans-4-oxoretinal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1b1 aldo-keto reductase family 1 member B JBrowse link 4 61,706,866 61,720,959 RGD:6480464
G Akr1b10 aldo-keto reductase family 1 member B10 JBrowse link 4 61,813,265 61,830,371 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        inhibitor 18143
          gap junctional intercellular communication inhibitor 33
            all-trans-retinal 33
              (3R)-all-trans-3-hydroxyretinal 0
              (3S)-all-trans-3-hydroxyretinal 0
              N-retinylidenephosphatidylethanolamine 0
              all-trans-4-hydroxyretinal 0
              all-trans-4-oxoretinal 2
              vitamin A + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic group 18407
                              organic divalent group 18397
                                organodiyl group 18397
                                  carbonyl group 18285
                                    carbonyl compound 18285
                                      carboxylic acid 17940
                                        carboacyl group 16948
                                          univalent carboacyl group 16948
                                            formyl group 7725
                                              aldehyde 7725
                                                alpha,beta-unsaturated aldehyde 1293
                                                  enal 1293
                                                    retinal 39
                                                      all-trans-retinal 33
                                                        (3R)-all-trans-3-hydroxyretinal 0
                                                        (3S)-all-trans-3-hydroxyretinal 0
                                                        N-retinylidenephosphatidylethanolamine 0
                                                        all-trans-4-hydroxyretinal 0
                                                        all-trans-4-oxoretinal 2
                                                        vitamin A + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.