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G |
Alb |
albumin |
multiple interactions increases expression |
ISO |
7-chloro-3-imino-5-methyl-2-azabicyclo(4.1.0)heptane inhibits the reaction [Hydrochloric Acid results in increased expression of ALB protein]; JTE 607 inhibits the reaction [Hydrochloric Acid results in increased expression of ALB protein] |
CTD |
PMID:15044056 PMID:15607125 |
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NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
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G |
Aqp4 |
aquaporin 4 |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of AQP4 protein |
CTD |
PMID:18406487 |
|
NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039
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G |
Areg |
amphiregulin |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of AREG mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
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G |
Bag3 |
BCL2-associated athanogene 3 |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of BAG3 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 7:128,125,307...128,148,705
Ensembl chr 7:128,125,340...128,148,705
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G |
Bglap |
bone gamma carboxyglutamate protein |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of BGLAP |
CTD |
PMID:17183249 |
|
NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
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G |
Calca |
calcitonin/calcitonin-related polypeptide, alpha |
affects response to substance |
ISO |
CALCA protein affects the susceptibility to Hydrochloric Acid |
CTD |
PMID:19483072 |
|
NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
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G |
Car3 |
carbonic anhydrase 3 |
multiple interactions |
EXP |
[NFE2L2 gene mutant form results in increased susceptibility to Hydrochloric Acid] which results in increased expression of CAR3 mRNA |
CTD |
PMID:29618784 |
|
NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583
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G |
Casp1 |
caspase 1 |
increases cleavage |
EXP |
Hydrochloric Acid results in increased cleavage of CASP1 protein |
CTD |
PMID:31900028 |
|
NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
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G |
Casp3 |
caspase 3 |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of CASP3 protein modified form |
CTD |
PMID:15046208 |
|
NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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G |
Casp9 |
caspase 9 |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of CASP9 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
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G |
Cat |
catalase |
multiple interactions |
ISO EXP |
CAT protein inhibits the reaction [Hydrochloric Acid results in increased susceptibility to Indomethacin] [Ethanol co-treated with Hydrochloric Acid] results in increased activity of CAT protein; boldine inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of CAT protein] |
CTD |
PMID:1887894 PMID:32531310 |
|
NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression multiple interactions |
ISO |
Hydrochloric Acid results in increased expression of CCL2 mRNA; Hydrochloric Acid results in increased expression of CCL2 protein pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL2 protein] |
CTD |
PMID:16129981 |
|
NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
increases expression multiple interactions |
ISO |
Hydrochloric Acid results in increased expression of CCL4 mRNA; Hydrochloric Acid results in increased expression of CCL4 protein pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL4 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL4 protein] |
CTD |
PMID:16129981 |
|
NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509
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G |
Ccna1 |
cyclin A1 |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of CCNA1 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 3:54,952,890...54,965,055
Ensembl chr 3:54,952,890...54,962,922
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G |
Ccnd1 |
cyclin D1 |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of CCND1 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
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G |
Ccne1 |
cyclin E1 |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of CCNE1 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
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G |
Ccne2 |
cyclin E2 |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of CCNE2 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 4:11,190,489...11,204,781
Ensembl chr 4:11,191,351...11,204,779
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G |
Cd86 |
CD86 antigen |
multiple interactions |
ISO |
Hydrochloric Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Hydrochloric Acid inhibits the reaction [imidazolidinyl urea results in increased expression of CD86 protein] |
CTD |
PMID:29743441 |
|
NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
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G |
Cdkn1b |
cyclin dependent kinase inhibitor 1B |
affects localization |
ISO |
Hydrochloric Acid affects the localization of CDKN1B protein |
CTD |
PMID:20818264 |
|
NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
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G |
Chrm3 |
cholinergic receptor, muscarinic 3, cardiac |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of CHRM3 protein |
CTD |
PMID:20719367 |
|
NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
multiple interactions increases expression |
ISO |
JTE 607 inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL1 mRNA] Hydrochloric Acid results in increased expression of CXCL1 mRNA; Hydrochloric Acid results in increased expression of CXCL1 protein |
CTD |
PMID:15044056 PMID:16129981 |
|
NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
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G |
Cxcl15 |
C-X-C motif chemokine ligand 15 |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of CXCL8 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
increases expression multiple interactions |
ISO |
Hydrochloric Acid results in increased expression of CXCL2 mRNA; Hydrochloric Acid results in increased expression of CXCL2 protein pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL2 protein] |
CTD |
PMID:16129981 |
|
NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
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G |
Cyba |
cytochrome b-245, alpha polypeptide |
increases expression |
EXP |
Hydrochloric Acid results in increased expression of CYBA protein |
CTD |
PMID:31900028 |
|
NCBI chr 8:123,151,510...123,159,679
Ensembl chr 8:123,151,515...123,159,669
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G |
Cybb |
cytochrome b-245, beta polypeptide |
increases expression |
EXP |
Hydrochloric Acid results in increased expression of CYBB protein |
CTD |
PMID:31900028 |
|
NCBI chr X:9,301,493...9,354,005
Ensembl chr X:9,301,491...9,354,010
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G |
Cyp2a5 |
cytochrome P450, family 2, subfamily a, polypeptide 5 |
increases expression multiple interactions |
EXP |
Hydrochloric Acid results in increased expression of CYP2A5 mRNA NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of CYP2A5 mRNA] |
CTD |
PMID:29618784 |
|
NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973
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G |
Dpys |
dihydropyrimidinase |
increases expression multiple interactions |
EXP |
Hydrochloric Acid results in increased expression of DPYS mRNA NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of DPYS mRNA] |
CTD |
PMID:29618784 |
|
NCBI chr15:39,631,881...39,720,866
Ensembl chr15:39,631,883...39,720,866
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G |
Dusp2 |
dual specificity phosphatase 2 |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of DUSP2 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 2:127,178,079...127,180,297
Ensembl chr 2:127,178,079...127,180,296
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G |
Dusp8 |
dual specificity phosphatase 8 |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of DUSP8 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 7:141,633,224...141,649,799
Ensembl chr 7:141,633,227...141,649,580
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G |
E2f5 |
E2F transcription factor 5 |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of E2F5 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 3:14,638,370...14,671,369
Ensembl chr 3:14,643,701...14,671,369
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G |
Edn1 |
endothelin 1 |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of EDN1 protein |
CTD |
PMID:19262391 |
|
NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
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G |
Efna4 |
ephrin A4 |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of EFNA4 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 3:89,240,700...89,245,335
Ensembl chr 3:89,240,697...89,245,335
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions increases expression |
ISO |
Celecoxib promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein]; Dipyrone promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein]; Piroxicam promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein] |
CTD |
PMID:15309881 |
|
NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
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G |
Emp1 |
epithelial membrane protein 1 |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of EMP1 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 6:135,339,548...135,360,171
Ensembl chr 6:135,339,543...135,360,171
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G |
Fgf2 |
fibroblast growth factor 2 |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of FGF2 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257
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G |
Fgfr3 |
fibroblast growth factor receptor 3 |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of FGFR3 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 5:33,879,068...33,894,412
Ensembl chr 5:33,879,018...33,894,412
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G |
Fos |
FBJ osteosarcoma oncogene |
multiple interactions increases expression |
ISO |
[Hydrochloric Acid co-treated with PGA5 protein] results in increased expression of FOS protein; Capsaicin inhibits the reaction [Hydrochloric Acid results in increased expression of FOS protein]; Hexamethonium inhibits the reaction [Hydrochloric Acid results in increased expression of FOS protein]; SB 222200 affects the reaction [Hydrochloric Acid results in increased expression of FOS mRNA]; vofopitant affects the reaction [Hydrochloric Acid results in increased expression of FOS mRNA] Hydrochloric Acid results in increased expression of FOS mRNA; Hydrochloric Acid results in increased expression of FOS protein |
CTD |
PMID:11730984 PMID:12588467 PMID:12928072 PMID:14750966 PMID:16162281 |
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NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
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G |
Fosl2 |
fos-like antigen 2 |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of FOSL2 mRNA |
CTD |
PMID:15046208 |
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NCBI chr 5:32,292,599...32,315,184
Ensembl chr 5:32,293,145...32,315,186
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G |
Gadd45a |
growth arrest and DNA-damage-inducible 45 alpha |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of GADD45A mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression multiple interactions |
EXP |
Hydrochloric Acid results in increased expression of GCLC mRNA NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of GCLC mRNA] |
CTD |
PMID:29618784 |
|
NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
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G |
Gclm |
glutamate-cysteine ligase, modifier subunit |
increases expression multiple interactions |
EXP |
Hydrochloric Acid results in increased expression of GCLM mRNA NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of GCLM mRNA] |
CTD |
PMID:29618784 |
|
NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
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G |
Gls |
glutaminase |
multiple interactions increases expression |
EXP |
[Hydrochloric Acid results in decreased expression of GLS protein] which results in increased secretion of Ammonia Hydrochloric Acid results in increased expression of GLS mRNA; Hydrochloric Acid results in increased expression of GLS protein |
CTD |
PMID:20719974 PMID:29618784 |
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NCBI chr 1:52,202,608...52,274,168
Ensembl chr 1:52,202,607...52,272,391
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G |
Glul |
glutamate-ammonia ligase |
multiple interactions |
EXP |
Hydrochloric Acid promotes the reaction [RHBG protein mutant form results in decreased expression of GLUL protein] |
CTD |
PMID:20719974 |
|
NCBI chr 1:153,775,692...153,785,469
Ensembl chr 1:153,775,690...153,785,469
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G |
Gsta3 |
glutathione S-transferase, alpha 3 |
increases expression multiple interactions |
EXP |
Hydrochloric Acid results in increased expression of GSTA3 mRNA NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of GSTA3 mRNA] |
CTD |
PMID:29618784 |
|
NCBI chr 1:21,310,837...21,335,885
Ensembl chr 1:21,310,813...21,335,885
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G |
Gstm1 |
glutathione S-transferase, mu 1 |
multiple interactions increases expression |
EXP |
NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of GSTM1 mRNA] |
CTD |
PMID:29618784 |
|
NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
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G |
Gtpbp2 |
GTP binding protein 2 |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of GTPBP2 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr17:46,470,153...46,480,294
Ensembl chr17:46,471,958...46,480,296
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
multiple interactions |
EXP |
[NFE2L2 gene mutant form results in increased susceptibility to Hydrochloric Acid] which results in increased expression of HAVCR1 mRNA |
CTD |
PMID:29618784 |
|
NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO |
beraprost inhibits the reaction [Hydrochloric Acid results in increased expression of HMOX1 protein]; Capsaicin promotes the reaction [Hydrochloric Acid results in increased expression of HMOX1 protein] |
CTD |
PMID:18617559 |
|
NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
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G |
Hsf1 |
heat shock factor 1 |
affects response to substance |
EXP |
HSF1 protein affects the susceptibility to Hydrochloric Acid |
CTD |
PMID:17189318 |
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NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113
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G |
Hspa1a |
heat shock protein 1A |
affects response to substance |
ISO |
HSPA1A protein affects the susceptibility to Hydrochloric Acid |
CTD |
PMID:16945336 |
|
NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
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G |
Hspa1b |
heat shock protein 1B |
affects response to substance |
ISO |
HSPA1B protein affects the susceptibility to Hydrochloric Acid |
CTD |
PMID:15338365 |
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NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214
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G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression multiple interactions |
ISO |
Hydrochloric Acid results in increased expression of ICAM1 mRNA pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of ICAM1 mRNA] Hydrochloric Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Hydrochloric Acid inhibits the reaction [imidazolidinyl urea results in increased expression of ICAM1 protein] |
CTD |
PMID:16129981 PMID:29743441 |
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NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
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G |
Id2 |
inhibitor of DNA binding 2 |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of ID2 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression |
ISO EXP |
[Celecoxib co-treated with Hydrochloric Acid] results in increased expression of IL1B protein Hydrochloric Acid results in increased expression of IL1B protein [Ethanol co-treated with Hydrochloric Acid] results in increased expression of IL1B protein; MitoTEMPO inhibits the reaction [Hydrochloric Acid results in increased expression of IL1B mRNA]; MitoTEMPO inhibits the reaction [Hydrochloric Acid results in increased expression of IL1B protein]; Thalidomide inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased expression of IL1B protein] Hydrochloric Acid results in increased expression of IL1B mRNA; Hydrochloric Acid results in increased expression of IL1B protein |
CTD |
PMID:15309881 PMID:25478868 PMID:31900028 |
|
NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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G |
Il5 |
interleukin 5 |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of IL5 protein |
CTD |
PMID:19951613 |
|
NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
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G |
Il6 |
interleukin 6 |
multiple interactions increases expression |
ISO EXP |
7-chloro-3-imino-5-methyl-2-azabicyclo(4.1.0)heptane inhibits the reaction [Hydrochloric Acid results in increased expression of IL6 protein]; JTE 607 inhibits the reaction [Hydrochloric Acid results in increased expression of IL6 mRNA]; JTE 607 inhibits the reaction [Hydrochloric Acid results in increased expression of IL6 protein] Hydrochloric Acid results in increased expression of IL6 mRNA; Hydrochloric Acid results in increased expression of IL6 protein [Ethanol co-treated with Hydrochloric Acid] results in increased expression of IL6 protein; MitoTEMPO inhibits the reaction [Hydrochloric Acid results in increased expression of IL6 mRNA]; MitoTEMPO inhibits the reaction [Hydrochloric Acid results in increased expression of IL6 protein]; Thalidomide inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased expression of IL6 protein] |
CTD |
PMID:11850527 PMID:12771618 PMID:15044056 PMID:15607125 PMID:19951613 PMID:25478868 PMID:31900028 More...
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NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
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G |
Kcna4 |
potassium voltage-gated channel, shaker-related subfamily, member 4 |
decreases activity decreases expression |
ISO |
Hydrochloric Acid results in decreased activity of KCNA4 protein Hydrochloric Acid results in decreased expression of KCNA4 protein |
CTD |
PMID:19279288 |
|
NCBI chr 2:107,120,934...107,157,149
Ensembl chr 2:107,120,984...107,128,847
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G |
Kdm5b |
lysine demethylase 5B |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of KDM5B mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 1:134,487,916...134,560,621
Ensembl chr 1:134,487,909...134,563,023
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G |
Mcl1 |
myeloid cell leukemia sequence 1 |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of MCL1 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487
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G |
Mcm4 |
minichromosome maintenance complex component 4 |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of MCM4 mRNA |
CTD |
PMID:15046208 |
|
NCBI chr16:15,441,761...15,455,264
Ensembl chr16:15,441,761...15,455,264
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G |
Mif |
macrophage migration inhibitory factor (glycosylation-inhibiting factor) |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of MIF mRNA; Hydrochloric Acid results in increased expression of MIF protein |
CTD |
PMID:12853844 |
|
NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074
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G |
Mmp1b |
matrix metallopeptidase 1b (interstitial collagenase) |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of MMP1 protein |
CTD |
PMID:11850527 |
|
NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
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G |
Mpo |
myeloperoxidase |
increases activity multiple interactions |
ISO EXP |
Hydrochloric Acid results in increased activity of MPO protein [Ethanol co-treated with Hydrochloric Acid] results in increased activity of MPO protein; [Ethanol co-treated with Hydrochloric Acid] results in increased expression of MPO protein; [lupeol binds to stearic acid] inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased expression of MPO protein]; baicalein inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of MPO protein]; boldine inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of MPO protein]; Carbenoxolone inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of MPO protein]; Carbenoxolone inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased expression of MPO protein]; Omeprazole inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of MPO protein]; Thalidomide inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of MPO protein] |
CTD |
PMID:11574821 PMID:15309881 PMID:25478868 PMID:27780710 PMID:31900028 PMID:32006539 PMID:32531310 More...
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NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
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Ncf2 |
neutrophil cytosolic factor 2 |
increases expression |
EXP |
Hydrochloric Acid results in increased expression of NCF2 protein |
CTD |
PMID:31900028 |
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NCBI chr 1:152,675,904...152,712,743
Ensembl chr 1:152,675,945...152,712,742
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Nfe2l2 |
nuclear factor, erythroid derived 2, like 2 |
increases localization multiple interactions increases response to substance |
ISO EXP |
Hydrochloric Acid results in increased localization of NFE2L2 protein [NFE2L2 gene mutant form results in increased susceptibility to Hydrochloric Acid] which results in increased expression of CAR3 mRNA; [NFE2L2 gene mutant form results in increased susceptibility to Hydrochloric Acid] which results in increased expression of HAVCR1 mRNA; [NFE2L2 gene mutant form results in increased susceptibility to Hydrochloric Acid] which results in increased expression of SLC38A1 mRNA; [NFE2L2 gene mutant form results in increased susceptibility to Hydrochloric Acid] which results in increased expression of SLC9A4 mRNA; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in decreased expression of SLC38A4 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in decreased expression of SLC3A2 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in decreased expression of SLC7A9 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of CYP2A5 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of DPYS mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of GCLC mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of GCLM mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of GSTA3 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of GSTM1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of NQO1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of SLC38A3 mRNA]; NFE2L2 protein promotes the reaction [Hydrochloric Acid results in increased expression of SLC38A3 mRNA] |
CTD |
PMID:18617559 PMID:29618784 |
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NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
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Nlrp3 |
NLR family, pyrin domain containing 3 |
increases expression |
EXP |
Hydrochloric Acid results in increased expression of NLRP3 protein |
CTD |
PMID:31900028 |
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NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
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Nos2 |
nitric oxide synthase 2, inducible |
affects response to substance multiple interactions increases expression |
EXP ISO |
NOS2 protein affects the susceptibility to Hydrochloric Acid pimagedine inhibits the reaction [Hydrochloric Acid results in increased expression of NOS2 protein]; Quercetin inhibits the reaction [Hydrochloric Acid results in increased expression of NOS2 protein]; S-methylisothiopseudouronium inhibits the reaction [Hydrochloric Acid results in increased expression of NOS2 protein] |
CTD |
PMID:11574821 PMID:12646421 PMID:12771618 PMID:18573544 PMID:24122261 |
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NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
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Nos3 |
nitric oxide synthase 3, endothelial cell |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of NOS3 protein |
CTD |
PMID:12771618 |
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NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
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Nox1 |
NADPH oxidase 1 |
affects response to substance |
EXP |
NOX1 protein affects the susceptibility to Hydrochloric Acid |
CTD |
PMID:21339339 |
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NCBI chr X:132,987,170...133,038,455
Ensembl chr X:132,987,170...133,122,705
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G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
increases expression multiple interactions |
EXP |
Hydrochloric Acid results in increased expression of NQO1 mRNA NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of NQO1 mRNA] |
CTD |
PMID:29618784 |
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NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
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Pck1 |
phosphoenolpyruvate carboxykinase 1, cytosolic |
increases expression |
EXP |
Hydrochloric Acid results in increased expression of PCK1 protein |
CTD |
PMID:20719974 |
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NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
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Pcna |
proliferating cell nuclear antigen |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of PCNA mRNA |
CTD |
PMID:15046208 |
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NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
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Pkd2 |
polycystin 2, transient receptor potential cation channel |
multiple interactions |
ISO |
Hydrochloric Acid results in decreased activity of [PKD2 protein binds to PKD2 protein] |
CTD |
PMID:19193631 |
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NCBI chr 5:104,599,379...104,653,685
Ensembl chr 5:104,607,316...104,653,685
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Plpp3 |
phospholipid phosphatase 3 |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of PLPP3 mRNA |
CTD |
PMID:15046208 |
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NCBI chr 4:105,014,544...105,089,964
Ensembl chr 4:105,014,544...105,089,961
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G |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
decreases response to substance multiple interactions |
EXP |
PTGS1 results in decreased susceptibility to Hydrochloric Acid PTGS1 results in decreased susceptibility to [Hydrochloric Acid co-treated with Aspirin] |
CTD |
PMID:15236176 |
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NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression |
EXP ISO |
[[Aspirin co-treated with Hydrochloric Acid] results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone; [Aspirin co-treated with Hydrochloric Acid] results in increased expression of PTGS2 mRNA; [Aspirin co-treated with Hydrochloric Acid] results in increased expression of PTGS2 protein [Aspirin co-treated with Hydrochloric Acid] results in increased expression of PTGS2 mRNA; [Hydrochloric Acid co-treated with Piroxicam] results in increased expression of PTGS2 mRNA Hydrochloric Acid results in increased expression of PTGS2 mRNA; Hydrochloric Acid results in increased expression of PTGS2 protein |
CTD |
PMID:9726391 PMID:12853844 PMID:15236176 PMID:15309881 |
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NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
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Pth |
parathyroid hormone |
decreases secretion |
ISO |
PTH protein results in decreased secretion of Hydrochloric Acid |
CTD |
PMID:20380354 |
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NCBI chr 7:112,984,783...112,987,879
Ensembl chr 7:112,984,787...112,987,777
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Pycard |
PYD and CARD domain containing |
increases expression |
EXP |
Hydrochloric Acid results in increased expression of PYCARD protein |
CTD |
PMID:31900028 |
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NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
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Rassf1 |
Ras association (RalGDS/AF-6) domain family member 1 |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of RASSF1 mRNA |
CTD |
PMID:15046208 |
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NCBI chr 9:107,428,752...107,439,460
Ensembl chr 9:107,428,754...107,439,466
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Rela |
v-rel reticuloendotheliosis viral oncogene homolog A (avian) |
multiple interactions increases phosphorylation |
EXP |
MitoTEMPO inhibits the reaction [Hydrochloric Acid results in increased phosphorylation of RELA protein] |
CTD |
PMID:31900028 |
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NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
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Rhbg |
Rhesus blood group-associated B glycoprotein |
multiple interactions increases expression |
EXP |
Hydrochloric Acid promotes the reaction [RHBG protein mutant form results in decreased expression of GLUL protein]; RHBG protein affects the reaction [Hydrochloric Acid results in increased export of Ammonia] Hydrochloric Acid results in increased expression of RHBG protein |
CTD |
PMID:20719974 |
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NCBI chr 3:88,150,181...88,162,046
Ensembl chr 3:88,150,181...88,162,016
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Rhcg |
Rhesus blood group-associated C glycoprotein |
increases expression multiple interactions affects response to substance |
EXP ISO |
Hydrochloric Acid results in increased expression of RHCG protein RHCG protein affects the reaction [Hydrochloric Acid results in increased secretion of Ammonia] RHCG protein affects the susceptibility to Hydrochloric Acid [Hydrochloric Acid results in increased expression of RHCG protein] which results in increased secretion of Ammonia |
CTD |
PMID:16144966 PMID:19321595 PMID:20462967 |
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NCBI chr 7:79,243,111...79,267,405
Ensembl chr 7:79,243,111...79,267,405
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Rrad |
Ras-related associated with diabetes |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of RRAD mRNA |
CTD |
PMID:15046208 |
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NCBI chr 8:105,354,702...105,357,921
Ensembl chr 8:105,354,702...105,357,959
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G |
Rreb1 |
ras responsive element binding protein 1 |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of RREB1 mRNA |
CTD |
PMID:15046208 |
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NCBI chr13:37,962,362...38,135,981
Ensembl chr13:37,962,376...38,135,981
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G |
Runx2 |
runt related transcription factor 2 |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of RUNX2 mRNA; Hydrochloric Acid results in increased expression of RUNX2 protein |
CTD |
PMID:17183249 |
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NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684
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Scgb1a1 |
secretoglobin, family 1A, member 1 |
increases expression multiple interactions |
ISO |
Hydrochloric Acid results in increased expression of SCGB1A1 protein Quercetin inhibits the reaction [Hydrochloric Acid results in increased expression of SCGB1A1 protein] |
CTD |
PMID:24122261 |
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NCBI chr19:9,061,006...9,065,320
Ensembl chr19:9,061,000...9,065,322
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Serpine1 |
serine (or cysteine) peptidase inhibitor, clade E, member 1 |
affects response to substance |
EXP |
SERPINE1 protein affects the susceptibility to Hydrochloric Acid |
CTD |
PMID:19060228 |
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NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
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G |
Sftpd |
surfactant associated protein D |
decreases expression increases expression multiple interactions |
ISO |
Hydrochloric Acid results in decreased expression of SFTPD protein Hydrochloric Acid results in increased expression of SFTPD protein S-methylisothiopseudouronium inhibits the reaction [Hydrochloric Acid results in decreased expression of SFTPD protein] |
CTD |
PMID:11880309 PMID:18573544 |
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NCBI chr14:40,894,169...40,907,155
Ensembl chr14:40,894,171...40,907,106
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G |
Slc38a1 |
solute carrier family 38, member 1 |
multiple interactions |
EXP |
[NFE2L2 gene mutant form results in increased susceptibility to Hydrochloric Acid] which results in increased expression of SLC38A1 mRNA |
CTD |
PMID:29618784 |
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NCBI chr15:96,469,299...96,541,396
Ensembl chr15:96,469,299...96,540,794
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G |
Slc38a3 |
solute carrier family 38, member 3 |
multiple interactions increases expression |
EXP |
NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of SLC38A3 mRNA]; NFE2L2 protein promotes the reaction [Hydrochloric Acid results in increased expression of SLC38A3 mRNA] |
CTD |
PMID:29618784 |
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NCBI chr 9:107,528,353...107,546,167
Ensembl chr 9:107,527,833...107,546,729
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G |
Slc38a4 |
solute carrier family 38, member 4 |
decreases expression multiple interactions |
EXP |
Hydrochloric Acid results in decreased expression of SLC38A4 mRNA NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in decreased expression of SLC38A4 mRNA] |
CTD |
PMID:29618784 |
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NCBI chr15:96,892,701...96,953,837
Ensembl chr15:96,892,701...96,953,837
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Slc38a7 |
solute carrier family 38, member 7 |
decreases expression |
EXP |
Hydrochloric Acid results in decreased expression of SLC38A7 mRNA |
CTD |
PMID:29618784 |
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NCBI chr 8:96,562,548...96,580,205
Ensembl chr 8:96,562,548...96,580,167
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G |
Slc3a2 |
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 |
decreases expression multiple interactions |
EXP |
Hydrochloric Acid results in decreased expression of SLC3A2 mRNA NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in decreased expression of SLC3A2 mRNA] |
CTD |
PMID:29618784 |
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NCBI chr19:8,684,931...8,700,733
Ensembl chr19:8,684,246...8,700,733
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Slc6a19 |
solute carrier family 6 (neurotransmitter transporter), member 19 |
decreases expression |
EXP |
Hydrochloric Acid results in decreased expression of SLC6A19 mRNA |
CTD |
PMID:29618784 |
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NCBI chr13:73,827,864...73,848,899
Ensembl chr13:73,827,864...73,852,984
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G |
Slc7a7 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 |
decreases expression |
EXP |
Hydrochloric Acid results in decreased expression of SLC7A7 mRNA |
CTD |
PMID:29618784 |
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NCBI chr14:54,606,899...54,657,525
Ensembl chr14:54,606,899...54,655,237
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G |
Slc7a9 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 |
multiple interactions decreases expression |
EXP |
NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in decreased expression of SLC7A9 mRNA] |
CTD |
PMID:29618784 |
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NCBI chr 7:35,148,152...35,165,459
Ensembl chr 7:35,148,221...35,165,461
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G |
Slc9a4 |
solute carrier family 9 (sodium/hydrogen exchanger), member 4 |
increases expression multiple interactions increases activity |
EXP ISO |
Hydrochloric Acid results in increased expression of SLC9A4 mRNA [NFE2L2 gene mutant form results in increased susceptibility to Hydrochloric Acid] which results in increased expression of SLC9A4 mRNA; SLC9A4 protein affects the reaction [Hydrochloric Acid results in increased secretion of Ammonia] Hydrochloric Acid results in increased activity of SLC9A4 protein |
CTD |
PMID:20484819 PMID:29618784 |
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NCBI chr 1:40,619,146...40,670,188
Ensembl chr 1:40,619,241...40,669,885
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Sod2 |
superoxide dismutase 2, mitochondrial |
decreases activity multiple interactions |
EXP |
Hydrochloric Acid results in decreased activity of SOD2 protein MitoTEMPO inhibits the reaction [Hydrochloric Acid results in decreased activity of SOD2 protein] |
CTD |
PMID:31900028 |
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NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
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G |
Sp7 |
Sp7 transcription factor 7 |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of SP7 mRNA; Hydrochloric Acid results in decreased expression of SP7 protein |
CTD |
PMID:17183249 |
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NCBI chr15:102,265,038...102,275,498
Ensembl chr15:102,265,041...102,275,617
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Sst |
somatostatin |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of SST protein |
CTD |
PMID:9530148 |
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NCBI chr16:23,708,327...23,710,041
Ensembl chr16:23,708,323...23,709,708
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G |
Sstr2 |
somatostatin receptor 2 |
affects response to substance |
EXP |
SSTR2 protein affects the susceptibility to Hydrochloric Acid |
CTD |
PMID:17363388 |
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NCBI chr11:113,510,153...113,516,854
Ensembl chr11:113,510,168...113,516,854
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G |
Tac1 |
tachykinin 1 |
multiple interactions increases secretion |
ISO |
Botulinum Toxins, Type A inhibits the reaction [Hydrochloric Acid results in increased secretion of TAC1 protein] |
CTD |
PMID:18184328 |
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NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
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G |
Tacr1 |
tachykinin receptor 1 |
affects response to substance |
ISO |
TACR1 protein affects the susceptibility to Hydrochloric Acid |
CTD |
PMID:11730984 |
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NCBI chr 6:82,378,990...82,537,085
Ensembl chr 6:82,379,315...82,537,085
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G |
Tacr3 |
tachykinin receptor 3 |
affects response to substance |
ISO |
TACR3 protein affects the susceptibility to Hydrochloric Acid |
CTD |
PMID:11730984 |
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NCBI chr 3:134,534,768...134,640,342
Ensembl chr 3:134,534,768...134,640,340
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G |
Tff2 |
trefoil factor 2 (spasmolytic protein 1) |
multiple interactions |
ISO |
[Aspirin co-treated with Hydrochloric Acid] results in increased expression of TFF2 mRNA |
CTD |
PMID:9726391 |
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NCBI chr17:31,360,036...31,363,256
Ensembl chr17:31,360,023...31,363,256
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G |
Tgfa |
transforming growth factor alpha |
multiple interactions increases expression |
ISO |
[Aspirin co-treated with Hydrochloric Acid] results in increased expression of TGFA mRNA; Celecoxib promotes the reaction [Hydrochloric Acid results in increased expression of TGFA protein]; Dipyrone promotes the reaction [Hydrochloric Acid results in increased expression of TGFA protein]; Piroxicam promotes the reaction [Hydrochloric Acid results in increased expression of TGFA protein] |
CTD |
PMID:9726391 PMID:15309881 |
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NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701
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Tnf |
tumor necrosis factor |
multiple interactions increases expression |
ISO EXP |
7-chloro-3-imino-5-methyl-2-azabicyclo(4.1.0)heptane inhibits the reaction [Hydrochloric Acid results in increased expression of TNF protein]; JTE 607 inhibits the reaction [Hydrochloric Acid results in increased expression of TNF mRNA]; JTE 607 inhibits the reaction [Hydrochloric Acid results in increased expression of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of TNF mRNA] Hydrochloric Acid results in increased expression of TNF mRNA; Hydrochloric Acid results in increased expression of TNF protein [Ethanol co-treated with Hydrochloric Acid] results in increased expression of TNF protein; boldine inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased expression of TNF protein]; MitoTEMPO inhibits the reaction [Hydrochloric Acid results in increased expression of TNF mRNA]; MitoTEMPO inhibits the reaction [Hydrochloric Acid results in increased expression of TNF protein]; Thalidomide inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased expression of TNF protein] |
CTD |
PMID:15044056 PMID:15607125 PMID:16129981 PMID:25478868 PMID:31900028 PMID:32531310 More...
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NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
affects response to substance increases activity |
EXP ISO |
TRPV1 protein affects the susceptibility to Hydrochloric Acid Hydrochloric Acid results in increased activity of TRPV1 protein |
CTD |
PMID:15125461 PMID:15331673 PMID:17627983 PMID:18331834 PMID:19483072 |
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NCBI chr11:73,124,975...73,152,148
Ensembl chr11:73,125,118...73,152,068
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G |
Vegfc |
vascular endothelial growth factor C |
increases expression |
ISO |
Hydrochloric Acid results in increased expression of VEGFC mRNA |
CTD |
PMID:15046208 |
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NCBI chr 8:54,530,567...54,639,489
Ensembl chr 8:54,530,641...54,640,131
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G |
Vgf |
VGF nerve growth factor inducible |
decreases expression |
ISO |
Hydrochloric Acid results in decreased expression of VGF mRNA |
CTD |
PMID:15046208 |
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NCBI chr 5:137,054,156...137,062,205
Ensembl chr 5:137,055,246...137,062,205
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