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ONTOLOGY REPORT - ANNOTATIONS


Term:glutathione disulfide
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Accession:CHEBI:17858 term browser browse the term
Definition:A glutathione derivative that has formula C20H32N6O12S2.
Synonyms:exact_synonym: (2S,2'S)-5,5'-[disulfanediylbis({(2R)-3-[(carboxymethyl)amino]-3-oxopropane-1,2-diyl}imino)]bis(2-amino-5-oxopentanoic acid)
 related_synonym: Formula=C20H32N6O12S2;   GSSG;   InChI=1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1;   InChIKey=YPZRWBKMTBYPTK-BJDJZHNGSA-N;   OXIDIZED GLUTATHIONE DISULFIDE;   Oxidized glutathione;   Oxiglutatione;   SMILES=N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O;   glutathione disulphide;   oxidised glutathione
 alt_id: CHEBI:14328;   CHEBI:14720;   CHEBI:24336;   CHEBI:42832;   CHEBI:7840
 xref: CAS:27025-41-8 "ChemIDplus";   CAS:27025-41-8 "KEGG COMPOUND";   DrugBank:DB03310;   Drug_Central:5130 "DrugCentral";   KEGG:C00127;   KEGG:D00031
 xref_mesh: MESH:D019803
 xref: PDBeChem:GDS
 cyclic_relationship: is_conjugate_acid_of CHEBI:58297


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glutathione disulfide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc1 ATP binding cassette subfamily C member 1 JBrowse link 10 549,537 672,235 RGD:6480464
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:6480464
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:6480464
G Alox12 arachidonate 12-lipoxygenase, 12S type JBrowse link 10 56,851,734 56,864,049 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:6480464
G Crygd crystallin, gamma D JBrowse link 9 71,776,568 71,778,323 RGD:6480464
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:6480464
G Glrx glutaredoxin JBrowse link 2 2,606,032 2,615,944 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:6480464
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6480464
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Slc2a4 solute carrier family 2 member 4 JBrowse link 10 56,552,921 56,558,562 RGD:6480464
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Sult1a1 sulfotransferase family 1A member 1 JBrowse link 1 198,100,586 198,104,106 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      chemical role 19114
        antioxidant 14059
          glutathione 368
            glutathione derivative 56
              glutathione disulfide 20
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              organic divalent group 18321
                                organodiyl group 18321
                                  carbonyl group 18209
                                    carbonyl compound 18209
                                      carboxylic acid 17908
                                        carboacyl group 16930
                                          univalent carboacyl group 16930
                                            carbamoyl group 16610
                                              carboxamide 16610
                                                peptide 9292
                                                  oligopeptide 1073
                                                    tripeptide 864
                                                      glutathione 368
                                                        glutathione derivative 56
                                                          glutathione disulfide 20
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.