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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:p-cresol
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Accession:CHEBI:17847 term browser browse the term
Definition:A cresol that consists of toluene substituted by a hydroxy group at position 4. It is a metabolite of aromatic amino acid metabolism produced by intestinal microflora in humans and animals.
Synonyms:related_synonym: 1-hydroxy-4-methylbenzene;   4-Cresol;   4-Hydroxytoluene;   4-methylphenol;   Formula=C7H8O;   InChI=1S/C7H8O/c1-6-2-4-7(8)5-3-6/h2-5,8H,1H3;   InChIKey=IWDCLRJOBJJRNH-UHFFFAOYSA-N;   SMILES=Cc1ccc(O)cc1;   p-Kresol;   p-methylphenol;   p-tolyl alcohol;   paracresol
 alt_id: CHEBI:11981;   CHEBI:1816;   CHEBI:20352;   CHEBI:44726
 xref: Beilstein:1305151;   CAS:106-44-5;   DrugBank:DB01688;   Gmelin:2779;   HMDB:HMDB0001858;   KEGG:C01468;   KNApSAcK:C00002645
 xref_mesh: MESH:C032538
 xref: MetaCyc:CPD-108;   PDBeChem:PCR;   PMID:12427124;   PMID:17660685;   Reaxys:1305151;   UM-BBD_compID:c0127;   Wikipedia:P-cresol


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p-cresol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2C41 cytochrome P450 2C41 affects metabolic processing EXP CYP2C11 protein affects the metabolism of 4-cresol CTD PMID:8592870
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 affects metabolic processing EXP CYP2E1 protein affects the metabolism of 4-cresol CTD PMID:8592870 NCBI chr28:41,079,164...41,089,188
Ensembl chr28:41,035,025...41,122,754 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 499
    role 499
      biological role 499
        poison 369
          toxin 32
            uremic toxin 2
              p-cresol 2
                4-(trifluoromethyl)phenol 0
                p-cresol sulfate 0
                tolterodine + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 499
    subatomic particle 499
      composite particle 499
        hadron 499
          baryon 499
            nucleon 499
              atomic nucleus 499
                atom 499
                  main group element atom 492
                    p-block element atom 492
                      carbon group element atom 481
                        carbon atom 480
                          organic molecular entity 480
                            organic molecule 471
                              organic cyclic compound 454
                                carbocyclic compound 193
                                  benzenoid aromatic compound 191
                                    benzenes 185
                                      toluenes 13
                                        hydroxytoluene 2
                                          cresol 2
                                            p-cresol 2
                                              4-(trifluoromethyl)phenol 0
                                              p-cresol sulfate 0
                                              tolterodine + 0
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