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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:serine
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Accession:CHEBI:17822 term browser browse the term
Definition:An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Synonyms:related_synonym: 2-Amino-3-hydroxypropionic acid;   2-amino-3-hydroxypropanoic acid;   3-Hydroxyalanine;   Formula=C3H7NO3;   InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7);   InChIKey=MTCFGRXMJLQNBG-UHFFFAOYSA-N;   SMILES=NC(CO)C(O)=O;   Serin
 alt_id: CHEBI:15081;   CHEBI:26648;   CHEBI:9116
 xref: Beilstein:1721402;   CAS:302-84-1;   Gmelin:26429;   KEGG:C00716;   KNApSAcK:C00001393;   Reaxys:1721402;   Wikipedia:Serine
 cyclic_relationship: is_conjugate_acid_of CHEBI:32845;   is_conjugate_base_of CHEBI:32846;   is_tautomer_of CHEBI:35243


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D-cycloserine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO Cycloserine inhibits the reaction [resveratrol results in increased expression of DDIT3 protein] CTD PMID:24264887 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Egr1 early growth response 1 increases expression EXP Cycloserine results in increased expression of EGR1 protein CTD PMID:19144966 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Cycloserine promotes the reaction [Clozapine results in increased expression of FOS mRNA] CTD PMID:12464447 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Homer1 homer scaffold protein 1 multiple interactions EXP Cycloserine inhibits the reaction [Clozapine results in increased expression of HOMER1 mRNA]; Cycloserine inhibits the reaction [Haloperidol results in increased expression of HOMER1 mRNA] CTD PMID:12464447 NCBI chr 2:22,909,550...23,012,303
Ensembl chr 2:22,909,569...23,009,678
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP Cycloserine inhibits the reaction [Dronabinol results in increased activity of MAPK1 protein] CTD PMID:11903061 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP Cycloserine inhibits the reaction [Dronabinol results in increased activity of MAPK3 protein] CTD PMID:11903061 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Cycloserine inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein] CTD PMID:24264887 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
Phe-Ser term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a1 solute carrier family 15 member 1 affects binding ISO phenylalanylserine analog binds to SLC15A1 protein CTD PMID:21147219 NCBI chr15:106,800,081...106,844,668
Ensembl chr15:106,800,081...106,844,426
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19792
      application 19465
        fuel 10817
          methanol 3073
            hydroxymethyl group 8
              serine 8
                3-oxoalanine + 0
                D-serine + 0
                L-serine + 1
                N-(2,4-dinitrophenyl)serine 0
                gougerotin 0
                serine derivative + 7
                serine residue + 0
                serino group + 0
                seryl group + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      carbon group element atom 19636
                        carbon atom 19625
                          organic molecular entity 19625
                            organic group 18537
                              organic divalent group 18528
                                organodiyl group 18528
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18113
                                        amino acid 14108
                                          polar amino acid 10656
                                            serine 8
                                              3-oxoalanine + 0
                                              D-serine + 0
                                              L-serine + 1
                                              N-(2,4-dinitrophenyl)serine 0
                                              gougerotin 0
                                              serine derivative + 7
                                              serine residue + 0
                                              serino group + 0
                                              seryl group + 0
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