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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-Hydroxybenzyl isothiocyanate
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Accession:CHEBI:178135 term browser browse the term
Synonyms:exact_synonym: 4-(isothiocyanatomethyl)phenol
 related_synonym: Formula=C8H7NOS;   InChI=1S/C8H7NOS/c10-8-3-1-7(2-4-8)5-9-6-11/h1-4,10H,5H2;   InChIKey=ATKWJXUJUNLTFU-UHFFFAOYSA-N;   SMILES=S=C=NCC1=CC=C(O)C=C1
 xref: CAS:2086-86-4;   Chemspider:141134;   HMDB:HMDB0032580
 xref_mesh: MESH:C031364



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4-Hydroxybenzyl isothiocyanate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase increases activity EXP 4-hydroxybenzyl isothiocyanate results in increased activity of CAT protein CTD PMID:22664424 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
EXP 4-hydroxybenzyl isothiocyanate results in increased expression of CYP1A1 mRNA
4-hydroxybenzyl isothiocyanate results in increased activity of [CYP1A1 protein co-treated with CYP1A2 protein]
CTD PMID:22664424 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
EXP 4-hydroxybenzyl isothiocyanate results in increased activity of [CYP1A1 protein co-treated with CYP1A2 protein]
4-hydroxybenzyl isothiocyanate results in increased expression of CYP1A2 mRNA
CTD PMID:22664424 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity
decreases expression
EXP 4-hydroxybenzyl isothiocyanate results in decreased activity of CYP3A2 protein
4-hydroxybenzyl isothiocyanate results in decreased expression of CYP3A2 mRNA
CTD PMID:22664424 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
increases activity
EXP 4-hydroxybenzyl isothiocyanate results in increased expression of HMOX1 mRNA; 4-hydroxybenzyl isothiocyanate results in increased expression of HMOX1 protein
4-hydroxybenzyl isothiocyanate results in increased activity of HMOX1 protein
CTD PMID:22664424 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression EXP 4-hydroxybenzyl isothiocyanate results in increased expression of NFE2L2 protein CTD PMID:22664424 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
increases activity
EXP 4-hydroxybenzyl isothiocyanate results in increased expression of NQO1 mRNA
4-hydroxybenzyl isothiocyanate results in increased activity of NQO1 protein
CTD PMID:22664424 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20057
    chemical entity 20068
      molecular entity 20056
        polyatomic entity 19987
          heteroatomic molecular entity 19923
            hydroxides 19434
              organic hydroxy compound 19001
                phenols 18667
                  4-Hydroxybenzyl isothiocyanate 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 20057
    subatomic particle 20056
      composite particle 20068
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19971
                    p-block element atom 19971
                      carbon group element atom 19889
                        carbon atom 19894
                          organic molecular entity 19882
                            organic molecule 19830
                              organic cyclic compound 19603
                                organic aromatic compound 19444
                                  phenols 18667
                                    4-Hydroxybenzyl isothiocyanate 7
paths to the root