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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:methanol
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Accession:CHEBI:17790 term browser browse the term
Definition:The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.
Synonyms:related_synonym: CH3OH;   Formula=CH4O;   InChI=1S/CH4O/c1-2/h2H,1H3;   InChIKey=OKKJLVBELUTLKV-UHFFFAOYSA-N;   MeOH;   Methyl alcohol;   Methylalkohol;   SMILES=CO;   Spirit of wood;   carbinol;   wood alcohol;   wood naphtha;   wood spirit
 alt_id: CHEBI:14588;   CHEBI:25227;   CHEBI:44080;   CHEBI:44553;   CHEBI:6816
 xref: Beilstein:1098229;   CAS:67-56-1;   Gmelin:449;   HMDB:HMDB0001875;   KEGG:C00132;   KEGG:D02309
 xref_mesh: MESH:D000432
 xref: MetaCyc:METOH;   PDBeChem:MOH;   PMID:11141607;   PMID:11430978;   PMID:11489599;   PMID:11680737;   PMID:11684179;   PMID:14012711;   PMID:14678513;   PMID:14760634;   PMID:15172721;   PMID:15906011;   PMID:16705261;   PMID:17451998;   PMID:17733096;   PMID:19064074;   PMID:19850112;   PMID:20314698;   Reaxys:1098229;   UM-BBD_compID:c0132;   Wikipedia:Methanol
 cyclic_relationship: is_conjugate_acid_of CHEBI:52090


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arecoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FN1 fibronectin 1 multiple interactions
increases expression		 EXP pyrazolanthrone inhibits the reaction [Arecoline results in increased expression of FN1 protein] CTD PMID:26908192 NCBI chr15:117,658,158...117,737,145
Ensembl chr15:117,658,099...117,731,014 		JBrowse link
G SERPINE1 serpin family E member 1 increases expression
multiple interactions		 EXP Arecoline results in increased expression of SERPINE1 protein
pyrazolanthrone inhibits the reaction [Arecoline results in increased expression of SERPINE1 protein]		 CTD PMID:26908192 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,547 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions
increases expression		 EXP Arecoline results in increased secretion of and results in increased activity of TGFB1 protein; pyrazolanthrone inhibits the reaction [Arecoline results in increased expression of TGFB1 mRNA] CTD PMID:26908192 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
aspartame term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENPEP glutamyl aminopeptidase multiple interactions
increases hydrolysis		 EXP 1,10-phenanthroline inhibits the reaction [ENPEP protein results in increased hydrolysis of Aspartame]; amastatin inhibits the reaction [ENPEP protein results in increased hydrolysis of Aspartame]; Calcium Chloride promotes the reaction [ENPEP protein results in increased hydrolysis of Aspartame] CTD PMID:8141778 NCBI chr 8:111,765,839...111,858,349
Ensembl chr 8:111,748,514...111,858,510 		JBrowse link
cocaine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDN1 endothelin 1 increases expression
multiple interactions		 EXP Cocaine results in increased expression of EDN1 protein
1,3-ditolylguanidine inhibits the reaction [Cocaine results in increased expression of EDN1 protein]; Haloperidol inhibits the reaction [Cocaine results in increased expression of EDN1 protein]		 CTD PMID:9714087 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
eplerenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions EXP Eplerenone inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein] CTD PMID:24512358 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183 		JBrowse link
KT 5823 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL4A2 collagen type IV alpha 2 chain multiple interactions
decreases expression		 EXP KT 5823 inhibits the reaction [NOC 18 results in increased expression of COL4A2 protein]
KT 5823 results in decreased expression of COL4A2 protein		 CTD PMID:21307347 NCBI chr11:76,996,885...77,161,617
Ensembl chr11:76,997,516...77,161,614 		JBrowse link
G COL4A3 collagen type IV alpha 3 chain decreases expression
multiple interactions		 EXP KT 5823 results in decreased expression of COL4A3 mRNA
KT 5823 inhibits the reaction [NOC 18 results in increased expression of COL4A3 mRNA]		 CTD PMID:21307347 NCBI chr15:128,611,640...128,763,331
Ensembl chr15:128,611,866...128,763,122 		JBrowse link
G ITGAV integrin subunit alpha V multiple interactions EXP KT 5823 inhibits the reaction [NOC 18 results in increased expression of [ITGAV protein binds to ITGB3 protein]] CTD PMID:21307347 NCBI chr15:91,604,666...91,711,843
Ensembl chr15:91,604,676...91,711,851 		JBrowse link
G ITGB3 integrin subunit beta 3 multiple interactions EXP KT 5823 inhibits the reaction [NOC 18 results in increased expression of [ITGAV protein binds to ITGB3 protein]] CTD PMID:21307347 NCBI chr12:16,694,466...16,752,228
Ensembl chr12:16,693,514...16,752,292 		JBrowse link
nifedipine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP3A29 cytochrome P450 family 3 subfamily A member 29 multiple interactions
increases oxidation		 EXP Ketoconazole inhibits the reaction [CYP3A29 protein results in increased oxidation of Nifedipine]; Troleandomycin inhibits the reaction [CYP3A29 protein results in increased oxidation of Nifedipine] CTD PMID:20863320 NCBI chr 3:6,738,502...6,778,121
Ensembl chr 3:6,738,486...6,778,944 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5052
    role 5044
      application 863
        fuel 14
          methanol 11
            CHOH group 0
            cis-heme d hydroxychlorin gamma-spirolactone methyl ester 0
            dimethyl fumarate 0
            dimethyl maleate 0
            hydroxymethyl group + 0
            methoxy group 0
            methyl L-cysteinate + 0
            methyl ester + 11
            methyl formate 0
            methyl nonanoate 0
            methyloxidanyl 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5052
    subatomic particle 5043
      composite particle 5043
        hadron 5071
          baryon 5043
            nucleon 5043
              atomic nucleus 5043
                atom 5043
                  main group element atom 5013
                    p-block element atom 5010
                      chalcogen 4915
                        oxygen atom 4910
                          oxygen molecular entity 4883
                            hydroxides 4835
                              organic hydroxy compound 4767
                                alcohol 4402
                                  aliphatic alcohol 144
                                    alkyl alcohol 144
                                      methanol 11
                                        CHOH group 0
                                        cis-heme d hydroxychlorin gamma-spirolactone methyl ester 0
                                        dimethyl fumarate 0
                                        dimethyl maleate 0
                                        hydroxymethyl group + 0
                                        methoxy group 0
                                        methyl L-cysteinate + 0
                                        methyl ester + 11
                                        methyl formate 0
                                        methyl nonanoate 0
                                        methyloxidanyl 0
paths to the root