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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:AL 8810
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Accession:CHEBI:177643 term browser browse the term
Synonyms:exact_synonym: (Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-luoro-5-hydroxycyclopentyl]hept-5-enoic acid
 related_synonym: Formula=C24H31FO4;   InChI=1S/C24H31FO4/c25-21-15-23(27)20(9-3-1-2-4-10-24(28)29)19(21)11-12-22(26)18-13-16-7-5-6-8-17(16)14-18/h1,3,5-8,11-12,18-23,26-27H,2,4,9-10,13-15H2,(H,28,29)/b3-1-,12-11+/t19-,20-,21+,22+,23+/m1/s1;   InChIKey=WTYSXBKKVNOOIX-JTGCGUAKSA-N;   SMILES=F[C@@H]1[C@@H]([C@H]([C@@H](O)C1)C/C=C\\CCCC(O)=O)/C=C/[C@H](O)C2CC=3C(C2)=CC=CC3
 xref: CAS:246246-19-5;   Chemspider:4470757
 xref_mesh: MESH:C121227



show annotations for term's descendants           Sort by:
AL 8810 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ereg epiregulin multiple interactions ISO [AL 8810 results in decreased activity of PTGFR protein] inhibits the reaction [[trans-10,cis-12-conjugated linoleic acid results in increased abundance of Dinoprost] which results in increased expression of EREG] CTD PMID:22583689 NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO AL 8810 results in increased expression of FABP4 mRNA CTD PMID:21236357 NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO AL 8810 inhibits the reaction [fluprostenol promotes the reaction [Oxidopamine results in increased expression of GCLM mRNA]] CTD PMID:33486071 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO AL 8810 inhibits the reaction [fluprostenol promotes the reaction [Oxidopamine results in increased expression of HMOX1 mRNA]] CTD PMID:33486071 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO AL 8810 inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK1 protein] CTD PMID:33486071 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO AL 8810 inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK3 protein] CTD PMID:33486071 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO AL 8810 inhibits the reaction [Oxidopamine affects the localization of NFE2L2 protein] CTD PMID:33486071 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO AL 8810 inhibits the reaction [fluprostenol promotes the reaction [Oxidopamine results in increased expression of NQO1 mRNA]] CTD PMID:33486071 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO AL 8810 results in increased expression of PPARG mRNA CTD PMID:21236357 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptgfr prostaglandin F receptor multiple interactions ISO [AL 8810 results in decreased activity of PTGFR protein] inhibits the reaction [[trans-10,cis-12-conjugated linoleic acid results in increased abundance of Dinoprost] which results in increased expression of EREG] CTD PMID:22583689 NCBI chr 2:243,390,820...243,426,647
Ensembl chr 2:240,733,375...240,765,650
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19909
    chemical entity 19907
      atom 19907
        nonmetal atom 19831
          carbon atom 19781
            organic molecular entity 19781
              lipid 18020
                fatty acid 16860
                  long-chain fatty acid 3479
                    AL 8810 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19909
    subatomic particle 19907
      composite particle 19907
        hadron 19907
          baryon 19907
            nucleon 19907
              atomic nucleus 19907
                atom 19907
                  main group element atom 19846
                    p-block element atom 19846
                      carbon group element atom 19784
                        carbon atom 19781
                          organic molecular entity 19781
                            heteroorganic entity 19540
                              organochalcogen compound 19301
                                organooxygen compound 19216
                                  carbon oxoacid 18696
                                    carboxylic acid 18693
                                      monocarboxylic acid 18028
                                        fatty acid 16860
                                          long-chain fatty acid 3479
                                            AL 8810 10
paths to the root