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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-methylumbelliferyl acetate
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Accession:CHEBI:17763 term browser browse the term
Definition:An acetate ester consiting of umbelliferone carrying a 7-O-acetyl group.
Synonyms:exact_synonym: 4-methyl-2-oxo-2H-chromen-7-yl acetate
 related_synonym: 4-methyl-7-acetyloxy coumarin;   7-(Acetyloxy)-4-methyl-2-benzopyrone;   7-(acetyloxy)-4-methyl-2H-1-benzopyran-2-one;   7-Acetoxy-4-methylcoumarin;   7-acetoxy-4-methylchromen-2-one;   Formula=C12H10O4;   InChI=1S/C12H10O4/c1-7-5-12(14)16-11-6-9(15-8(2)13)3-4-10(7)11/h3-6H,1-2H3;   InChIKey=HXVZGASCDAGAPS-UHFFFAOYSA-N;   SMILES=CC(=O)Oc1ccc2c(C)cc(=O)oc2c1;   beta-Methylumbelliferyl acetate
 alt_id: CHEBI:110551;   CHEBI:12031;   CHEBI:1906;   CHEBI:20453
 xref: CAS:2747-05-9;   HMDB:HMDB0032989;   KEGG:C03837
 xref_mesh: MESH:C032078
 xref: MetaCyc:CPD-181;   PMID:11888210;   PMID:23245880;   Patent:US2008009544;   Patent:WO2007107846;   Reaxys:189667


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4-methylumbelliferyl acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calr calreticulin increases activity ISO 4-methylumbelliferyl acetate results in increased activity of CALR protein CTD PMID:20188080 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
increases hydrolysis
ISO Atropine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate]; Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate]; tropacocaine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] CTD PMID:9311626 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Ces2h carboxylesterase 2H increases hydrolysis ISO CES2 protein results in increased hydrolysis of 4-methylumbelliferyl acetate CTD PMID:9169443 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Txn1 thioredoxin 1 increases activity ISO 4-methylumbelliferyl acetate results in increased activity of TXN protein CTD PMID:24103856 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO 4-methylumbelliferyl acetate results in increased expression of VEGFA protein CTD PMID:24103856 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      application 19420
        probe 485
          fluorescent probe 418
            umbelliferone 81
              4-methylumbelliferyl acetate 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic molecule 19514
                              organic cyclic compound 19311
                                organic heterocyclic compound 18425
                                  oxacycle 17200
                                    benzopyran 10149
                                      1-benzopyran 9865
                                        chromenes 933
                                          chromenone 854
                                            coumarins 575
                                              hydroxycoumarin 301
                                                umbelliferone 81
                                                  4-methylumbelliferyl acetate 5
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