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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-methylumbelliferyl acetate
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Accession:CHEBI:17763 term browser browse the term
Definition:An acetate ester consiting of umbelliferone carrying a 7-O-acetyl group.
Synonyms:exact_synonym: 4-methyl-2-oxo-2H-chromen-7-yl acetate
 related_synonym: 4-methyl-7-acetyloxy coumarin;   7-(Acetyloxy)-4-methyl-2-benzopyrone;   7-(acetyloxy)-4-methyl-2H-1-benzopyran-2-one;   7-Acetoxy-4-methylcoumarin;   7-acetoxy-4-methylchromen-2-one;   Formula=C12H10O4;   InChI=1S/C12H10O4/c1-7-5-12(14)16-11-6-9(15-8(2)13)3-4-10(7)11/h3-6H,1-2H3;   InChIKey=HXVZGASCDAGAPS-UHFFFAOYSA-N;   SMILES=CC(=O)Oc1ccc2c(C)cc(=O)oc2c1;   beta-Methylumbelliferyl acetate
 alt_id: CHEBI:110551;   CHEBI:12031;   CHEBI:1906;   CHEBI:20453
 xref: CAS:2747-05-9;   HMDB:HMDB0032989;   KEGG:C03837
 xref_mesh: MESH:C032078
 xref: MetaCyc:CPD-181;   PMID:11888210;   PMID:23245880;   Patent:US2008009544;   Patent:WO2007107846;   Reaxys:189667


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4-methylumbelliferyl acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calr calreticulin increases activity ISO 4-methylumbelliferyl acetate results in increased activity of CALR protein CTD PMID:20188080 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
increases hydrolysis		 ISO Atropine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate]; Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate]; tropacocaine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] CTD PMID:9311626 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Ces2h carboxylesterase 2H increases hydrolysis ISO CES2 protein results in increased hydrolysis of 4-methylumbelliferyl acetate CTD PMID:9169443 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830 		JBrowse link
G Txn1 thioredoxin 1 increases activity ISO 4-methylumbelliferyl acetate results in increased activity of TXN protein CTD PMID:24103856 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO 4-methylumbelliferyl acetate results in increased expression of VEGFA protein CTD PMID:24103856 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19784
      application 19615
        probe 504
          fluorescent probe 434
            umbelliferone 104
              4-methylumbelliferyl acetate 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19810
      composite particle 19810
        hadron 19810
          baryon 19810
            nucleon 19810
              atomic nucleus 19810
                atom 19810
                  main group element atom 19755
                    p-block element atom 19755
                      carbon group element atom 19698
                        carbon atom 19693
                          organic molecular entity 19693
                            organic molecule 19651
                              organic cyclic compound 19457
                                organic heterocyclic compound 18816
                                  oxacycle 17773
                                    benzopyran 11699
                                      1-benzopyran 11461
                                        chromenes 4397
                                          chromenone 4347
                                            coumarins 4130
                                              hydroxycoumarin 337
                                                umbelliferone 104
                                                  4-methylumbelliferyl acetate 5
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