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ONTOLOGY REPORT - ANNOTATIONS


Term:desmosterol
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Accession:CHEBI:17737 term browser browse the term
Definition:A cholestanoid that is cholesta-5,24-diene substituted by a beta-hydroxy group at position 3. It is an intermediate metabolite obtained during the synthesis of cholesterol.
Synonyms:related_synonym: 24-Dehydrocholesterol;   3beta-cholesta-5,24-dien-3-ol;   Cholesta-5,24-dien-3beta-ol;   Formula=C27H44O;   InChI=1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9,19,21-25,28H,6,8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1;   InChIKey=AVSXSVCZWQODGV-DPAQBDIFSA-N;   SMILES=[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC=C(C)C
 alt_id: CHEBI:14130;   CHEBI:23646;   CHEBI:4451
 xref: CAS:313-04-2 "ChemIDplus";   CAS:313-04-2 "KEGG COMPOUND";   CAS:313-04-2 "NIST Chemistry WebBook";   HMDB:HMDB0002719;   KEGG:C01802;   KNApSAcK:C00023743;   LIPID_MAPS_instance:LMST01010016 "LIPID MAPS"
 xref_mesh: MESH:D003897
 xref: MetaCyc:DESMOSTEROL-CPD;   PMID:19115107 "Europe PMC";   PMID:23042211 "Europe PMC";   PMID:24095826 "Europe PMC";   PMID:24378747 "Europe PMC";   PMID:5432584 "Europe PMC";   Reaxys:2338693 "Reaxys";   Wikipedia:Desmosterol


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desmosterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca1 ATP binding cassette subfamily A member 1 JBrowse link 5 69,857,717 69,983,042 RGD:6480464
G Clec4e C-type lectin domain family 4, member E JBrowse link 4 156,271,087 156,276,243 RGD:6480464
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:6480464
G Dhcr24 24-dehydrocholesterol reductase JBrowse link 5 126,164,708 126,188,926 RGD:6480464
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
G Insig1 insulin induced gene 1 JBrowse link 4 342,302 350,515 RGD:6480464
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:6480464
G Scd stearoyl-CoA desaturase JBrowse link 1 264,159,966 264,173,061 RGD:6480464
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19617
    chemical entity 19615
      atom 19613
        nonmetal atom 19477
          carbon atom 19355
            organic molecular entity 19355
              lipid 16836
                steroid 12547
                  C27-steroid 305
                    desmosterol 10
                      (24Z),26-hydroxydesmosterol 0
                      24(S),25-epoxycholesterol 0
                      7-dehydrodesmosterol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19617
    subatomic particle 19613
      composite particle 19613
        hadron 19613
          baryon 19613
            nucleon 19613
              atomic nucleus 19613
                atom 19613
                  main group element atom 19491
                    p-block element atom 19491
                      carbon group element atom 19363
                        carbon atom 19355
                          organic molecular entity 19355
                            organic molecule 19272
                              organic cyclic compound 19062
                                organic polycyclic compound 15983
                                  steroid 12547
                                    hydroxy steroid 12099
                                      3-hydroxy steroid 9987
                                        3beta-hydroxy steroid 1969
                                          3beta-hydroxy-Delta(5)-steroid 1832
                                            desmosterol 10
                                              (24Z),26-hydroxydesmosterol 0
                                              24(S),25-epoxycholesterol 0
                                              7-dehydrodesmosterol 0
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