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ONTOLOGY REPORT - ANNOTATIONS


Term:desmosterol
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Accession:CHEBI:17737 term browser browse the term
Definition:A cholestanoid that is cholesta-5,24-diene substituted by a beta-hydroxy group at position 3. It is an intermediate metabolite obtained during the synthesis of cholesterol.
Synonyms:related_synonym: 24-Dehydrocholesterol;   3beta-cholesta-5,24-dien-3-ol;   Cholesta-5,24-dien-3beta-ol;   Formula=C27H44O;   InChI=1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9,19,21-25,28H,6,8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1;   InChIKey=AVSXSVCZWQODGV-DPAQBDIFSA-N;   SMILES=[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC=C(C)C
 alt_id: CHEBI:14130;   CHEBI:23646;   CHEBI:4451
 xref: CAS:313-04-2;   HMDB:HMDB0002719;   KEGG:C01802;   KNApSAcK:C00023743;   LIPID_MAPS_instance:LMST01010016
 xref_mesh: MESH:D003897
 xref: MetaCyc:DESMOSTEROL-CPD;   PMID:19115107;   PMID:23042211;   PMID:24095826;   PMID:24378747;   PMID:5432584;   Reaxys:2338693;   Wikipedia:Desmosterol


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desmosterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca1 ATP binding cassette subfamily A member 1 JBrowse link 5 69,857,717 69,983,042 RGD:6480464
G Clec4e C-type lectin domain family 4, member E JBrowse link 4 156,271,087 156,276,243 RGD:6480464
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:6480464
G Dhcr24 24-dehydrocholesterol reductase JBrowse link 5 126,164,708 126,188,926 RGD:6480464
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
G Insig1 insulin induced gene 1 JBrowse link 4 342,302 350,515 RGD:6480464
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:6480464
G Marchf6 membrane associated ring-CH-type finger 6 JBrowse link 2 84,533,546 84,608,743 RGD:6480464
G Scd stearoyl-CoA desaturase JBrowse link 1 264,159,966 264,173,061 RGD:6480464
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19779
    chemical entity 19778
      atom 19777
        nonmetal atom 19651
          carbon atom 19548
            organic molecular entity 19548
              lipid 16979
                steroid 12802
                  C27-steroid 317
                    desmosterol 11
                      (24Z),26-hydroxydesmosterol 0
                      24(S),25-epoxycholesterol 0
                      7-dehydrodesmosterol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19779
    subatomic particle 19777
      composite particle 19777
        hadron 19777
          baryon 19777
            nucleon 19777
              atomic nucleus 19777
                atom 19777
                  main group element atom 19664
                    p-block element atom 19664
                      carbon group element atom 19559
                        carbon atom 19548
                          organic molecular entity 19548
                            organic molecule 19472
                              organic cyclic compound 19236
                                organic polycyclic compound 16398
                                  steroid 12802
                                    hydroxy steroid 12382
                                      3-hydroxy steroid 10004
                                        3beta-hydroxy steroid 1994
                                          3beta-hydroxy-Delta(5)-steroid 1840
                                            desmosterol 11
                                              (24Z),26-hydroxydesmosterol 0
                                              24(S),25-epoxycholesterol 0
                                              7-dehydrodesmosterol 0
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