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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2,3-bisphospho-D-glyceric acid
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Accession:CHEBI:17720 term browser browse the term
Definition:The D-enantiomer of 2,3-bisphosphoglyceric acid.
Synonyms:related_synonym: (2R)-2,3-bis(phosphonooxy)-Propanoic acid;   2,3-BPG;   2,3-Bisphospho-D-glycerate;   2,3-Bisphosphoglyceric acid;   2,3-Disphospho-D-glycerate;   2,3-diphosphoglyceric acid;   D-Greenwald ester;   DPG;   Formula=C3H8O10P2;   Glyceric acid bis(dihydrogen phosphate);   Glyceric acid diphosphate;   InChI=1S/C3H8O10P2/c4-3(5)2(13-15(9,10)11)1-12-14(6,7)8/h2H,1H2,(H,4,5)(H2,6,7,8)(H2,9,10,11)/t2-/m1/s1;   InChIKey=XOHUEYCVLUUEJJ-UWTATZPHSA-N;   SMILES=OC(=O)[C@@H](COP(O)(O)=O)OP(O)(O)=O
 alt_id: CHEBI:11417;   CHEBI:19306;   CHEBI:872
 xref: CAS:138-81-8;   HMDB:HMDB0001294;   KEGG:C01159
 xref_mesh: MESH:D019794
 xref: MetaCyc:23-DIPHOSPHOGLYCERATE;   PDBeChem:DG2;   PMID:1257232;   PMID:15882454;   PMID:2111310;   PMID:3702645;   PMID:625775;   PMID:685194;   PMID:7308813;   PMID:7376803;   PMID:8735521;   PMID:9708696;   Reaxys:1729440
 cyclic_relationship: is_conjugate_acid_of CHEBI:58248


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2,3-bisphospho-D-glyceric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf6 ADP-ribosylation factor 6 multiple interactions ISO 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]]; 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein mutant form promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]] CTD PMID:10931844 NCBI chr12:69,418,924...69,422,754
Ensembl chr12:69,418,924...69,420,557 		JBrowse link
G Bglap bone gamma carboxyglutamate protein decreases activity ISO 2,3-Diphosphoglycerate results in decreased activity of BGLAP protein CTD PMID:16857255 NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771 		JBrowse link
G Pld1 phospholipase D1 decreases activity ISO 2,3-Diphosphoglycerate results in decreased activity of PLD1 protein CTD PMID:16857255 NCBI chr 3:27,992,636...28,187,388
Ensembl chr 3:27,992,844...28,187,511 		JBrowse link
G Sts steroid sulfatase multiple interactions ISO 2,3-Diphosphoglycerate inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:168,856,332...169,015,037
Ensembl chr  X:168,909,030...169,014,924 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      biological role 22162
        biochemical role 21431
          metabolite 21379
            fundamental metabolite 14986
              glyceric acid 6
                2,3-bisphosphoglyceric acid 4
                  2,3-bisphospho-D-glyceric acid 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      chalcogen 21431
                        oxygen atom 21437
                          oxygen molecular entity 21409
                            hydroxides 20789
                              oxoacid 20101
                                pnictogen oxoacid 13699
                                  phosphorus oxoacid 12721
                                    phosphoric acids 11722
                                      phosphoric acid 11710
                                        phosphoric acid derivative 11512
                                          phosphate 11511
                                            organic phosphate 11511
                                              carbohydrate phosphate 1855
                                                aldonic acid phosphate 6
                                                  phosphoglyceric acid 6
                                                    bisphosphoglyceric acid 4
                                                      2,3-bisphosphoglyceric acid 4
                                                        2,3-bisphospho-D-glyceric acid 4
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