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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2,3-bisphospho-D-glyceric acid
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Accession:CHEBI:17720 term browser browse the term
Definition:The D-enantiomer of 2,3-bisphosphoglyceric acid.
Synonyms:related_synonym: (2R)-2,3-bis(phosphonooxy)-Propanoic acid;   2,3-BPG;   2,3-Bisphospho-D-glycerate;   2,3-Bisphosphoglyceric acid;   2,3-Disphospho-D-glycerate;   2,3-diphosphoglyceric acid;   D-Greenwald ester;   DPG;   Formula=C3H8O10P2;   Glyceric acid bis(dihydrogen phosphate);   Glyceric acid diphosphate;   InChI=1S/C3H8O10P2/c4-3(5)2(13-15(9,10)11)1-12-14(6,7)8/h2H,1H2,(H,4,5)(H2,6,7,8)(H2,9,10,11)/t2-/m1/s1;   InChIKey=XOHUEYCVLUUEJJ-UWTATZPHSA-N;   SMILES=OC(=O)[C@@H](COP(O)(O)=O)OP(O)(O)=O
 alt_id: CHEBI:11417;   CHEBI:19306;   CHEBI:872
 xref: CAS:138-81-8;   HMDB:HMDB0001294;   KEGG:C01159
 xref_mesh: MESH:D019794
 xref: MetaCyc:23-DIPHOSPHOGLYCERATE;   PDBeChem:DG2;   PMID:1257232;   PMID:15882454;   PMID:2111310;   PMID:3702645;   PMID:625775;   PMID:685194;   PMID:7308813;   PMID:7376803;   PMID:8735521;   PMID:9708696;   Reaxys:1729440
 cyclic_relationship: is_conjugate_acid_of CHEBI:58248



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2,3-bisphospho-D-glyceric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf6 ADP-ribosylation factor 6 multiple interactions ISO 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]]; 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein mutant form promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]] CTD PMID:10931844 NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases activity ISO 2,3-Diphosphoglycerate results in decreased activity of BGLAP protein CTD PMID:16857255 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Pld1 phospholipase D1 decreases activity ISO 2,3-Diphosphoglycerate results in decreased activity of PLD1 protein CTD PMID:16857255 NCBI chr 2:110,849,205...111,047,692
Ensembl chr 2:110,893,608...111,047,692
JBrowse link
G Sts steroid sulfatase multiple interactions ISO 2,3-Diphosphoglycerate inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          metabolite 19344
            fundamental metabolite 12781
              glyceric acid 6
                2,3-bisphosphoglyceric acid 4
                  2,3-bisphospho-D-glyceric acid 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      chalcogen 19450
                        oxygen atom 19423
                          oxygen molecular entity 19423
                            hydroxides 19158
                              oxoacid 18472
                                pnictogen oxoacid 10733
                                  phosphorus oxoacid 9728
                                    phosphoric acids 8536
                                      phosphoric acid 8536
                                        phosphoric acid derivative 8242
                                          phosphate 8242
                                            organic phosphate 8241
                                              carbohydrate phosphate 1738
                                                aldonic acid phosphate 6
                                                  phosphoglyceric acid 6
                                                    bisphosphoglyceric acid 4
                                                      2,3-bisphosphoglyceric acid 4
                                                        2,3-bisphospho-D-glyceric acid 4
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