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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2,3-bisphospho-D-glyceric acid
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Accession:CHEBI:17720 term browser browse the term
Definition:The D-enantiomer of 2,3-bisphosphoglyceric acid.
Synonyms:related_synonym: (2R)-2,3-bis(phosphonooxy)-Propanoic acid;   2,3-BPG;   2,3-Bisphospho-D-glycerate;   2,3-Bisphosphoglyceric acid;   2,3-Disphospho-D-glycerate;   2,3-diphosphoglyceric acid;   D-Greenwald ester;   DPG;   Formula=C3H8O10P2;   Glyceric acid bis(dihydrogen phosphate);   Glyceric acid diphosphate;   InChI=1S/C3H8O10P2/c4-3(5)2(13-15(9,10)11)1-12-14(6,7)8/h2H,1H2,(H,4,5)(H2,6,7,8)(H2,9,10,11)/t2-/m1/s1;   InChIKey=XOHUEYCVLUUEJJ-UWTATZPHSA-N;   SMILES=OC(=O)[C@@H](COP(O)(O)=O)OP(O)(O)=O
 alt_id: CHEBI:11417;   CHEBI:19306;   CHEBI:872
 xref: CAS:138-81-8;   HMDB:HMDB0001294;   KEGG:C01159
 xref_mesh: MESH:D019794
 xref: MetaCyc:23-DIPHOSPHOGLYCERATE;   PDBeChem:DG2;   PMID:1257232;   PMID:15882454;   PMID:2111310;   PMID:3702645;   PMID:625775;   PMID:685194;   PMID:7308813;   PMID:7376803;   PMID:8735521;   PMID:9708696;   Reaxys:1729440
 cyclic_relationship: is_conjugate_acid_of CHEBI:58248


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2,3-bisphospho-D-glyceric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf6 ADP-ribosylation factor 6 multiple interactions ISO 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]]; 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein mutant form promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]] CTD PMID:10931844 NCBI chr 6:91,697,109...91,698,257
Ensembl chr 6:91,697,109...91,698,255
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases activity ISO 2,3-Diphosphoglycerate results in decreased activity of BGLAP protein CTD PMID:16857255 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Pld1 phospholipase D1 decreases activity ISO 2,3-Diphosphoglycerate results in decreased activity of PLD1 protein CTD PMID:16857255 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403
JBrowse link
G Sts steroid sulfatase multiple interactions ISO 2,3-Diphosphoglycerate inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:45,420,418...45,428,748
Ensembl chr  X:45,420,596...45,428,750
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            fundamental metabolite 12607
              glyceric acid 6
                2,3-bisphosphoglyceric acid 4
                  2,3-bisphospho-D-glyceric acid 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      chalcogen 19362
                        oxygen atom 19323
                          oxygen molecular entity 19323
                            hydroxides 19068
                              oxoacid 18193
                                pnictogen oxoacid 10146
                                  phosphorus oxoacid 9033
                                    phosphoric acids 7795
                                      phosphoric acid 7795
                                        phosphoric acid derivative 7474
                                          phosphate 7474
                                            organic phosphate 7473
                                              carbohydrate phosphate 1529
                                                aldonic acid phosphate 6
                                                  phosphoglyceric acid 6
                                                    bisphosphoglyceric acid 4
                                                      2,3-bisphosphoglyceric acid 4
                                                        2,3-bisphospho-D-glyceric acid 4
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