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ONTOLOGY REPORT - ANNOTATIONS


Term:lactose
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Accession:CHEBI:17716 term browser browse the term
Definition:A glycosylglucose disaccharide, found most notably in milk, that consists of D-galactose and D-glucose fragments bonded through a beta-1->4 glycosidic linkage. The glucose fragment can be in either the alpha- or beta-pyranose form, whereas the galactose fragment can only have the beta-pyranose form.
Synonyms:related_synonym: (Gal)1 (Glc)1;   1-beta-D-Galactopyranosyl-4-D-glucopyranose;   4-(beta-D-galactosido)-D-glucose;   4-O-beta-D-galactopyranosyl-D-glucose;   D-lactose;   Formula=C12H22O11;   Galbeta1-4Glc;   InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11?,12+/m1/s1;   InChIKey=GUBGYTABKSRVRQ-QKKXKWKRSA-N;   Lac;   Laktobiose;   Laktose;   Milchzucker;   SMILES=OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)OC(O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O;   beta-D-Gal-(1->4)-D-Glc;   beta-D-Galp-(1->4)-D-Glcp;   beta-Gal1,4-Glc;   lactobiose;   milk sugar
 alt_id: CHEBI:10296;   CHEBI:10380;   CHEBI:14497;   CHEBI:22460;   CHEBI:22760;   CHEBI:25005;   CHEBI:27755;   CHEBI:613009
 xref: Beilstein:1292745;   CAS:63-42-3;   GlyTouCan:G74621DY;   Gmelin:882872;   KEGG:C00243;   KEGG:D00046;   KEGG:G10504;   KNApSAcK:C00001136
 xref_mesh: MESH:D007785
 xref: PMID:1292745;   PMID:17329833;   PMID:18300214;   PMID:19053747;   PMID:19846069;   PMID:19913595;   PMID:20094999;   PMID:20503067;   PMID:20699559;   PMID:20873837;   PMID:20961532;   PMID:21403918;   PMID:2432147;   PMID:2456994;   PMID:28690131;   PMID:28807538;   PMID:6194884;   PMID:7574700;   Reaxys:1292745


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lactose term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Lgals3 galectin 3 JBrowse link 15 24,153,602 24,165,537 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19717
      biological role 19716
        biochemical role 19207
          metabolite 19182
            eukaryotic metabolite 18798
              animal metabolite 18521
                mammalian metabolite 18503
                  human metabolite 18149
                    lactose 3
                      2'-fucosyllactose + 0
                      3-(hexadecylsulfonyl)-2-[(hexadecylsulfonyl)methyl]propyl beta-D-galactosyl-(1->4)-beta-D-glucoside 0
                      3-fucosyllactose 0
                      D-Galp-(1->3)-beta-D-Galp-(1->4)-D-Glcp 0
                      D-Galp-(1->6)-beta-D-Galp-(1->4)-D-Glcp 0
                      alpha-L-Fucp-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                      alpha-lactose + 0
                      beta-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-Glcp 0
                      beta-D-Galp-(1->4)-[alpha-D-Glcp-(1->2)]-D-Glcp 0
                      beta-D-Galp-(1->6)-beta-D-Galp-(1->4)-D-Glcp 0
                      beta-D-GlcpNAc-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                      beta-D-GlcpNAc-(1->6)-beta-D-Galp-(1->4)-D-Glcp 0
                      beta-L-Fucp-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                      beta-lactose + 0
                      lactobionic acid + 0
                      lactose 6'-phosphate 0
                      lactose phosphate + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    p-block element atom 19655
                      carbon group element atom 19548
                        carbon atom 19537
                          organic molecular entity 19537
                            heteroorganic entity 19129
                              organochalcogen compound 18828
                                organooxygen compound 18747
                                  carbohydrates and carbohydrate derivatives 12146
                                    carbohydrate 12146
                                      oligosaccharide 506
                                        disaccharide 414
                                          glycosylglucose 170
                                            lactose 3
                                              2'-fucosyllactose + 0
                                              3-(hexadecylsulfonyl)-2-[(hexadecylsulfonyl)methyl]propyl beta-D-galactosyl-(1->4)-beta-D-glucoside 0
                                              3-fucosyllactose 0
                                              D-Galp-(1->3)-beta-D-Galp-(1->4)-D-Glcp 0
                                              D-Galp-(1->6)-beta-D-Galp-(1->4)-D-Glcp 0
                                              alpha-L-Fucp-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                                              alpha-lactose + 0
                                              beta-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-Glcp 0
                                              beta-D-Galp-(1->4)-[alpha-D-Glcp-(1->2)]-D-Glcp 0
                                              beta-D-Galp-(1->6)-beta-D-Galp-(1->4)-D-Glcp 0
                                              beta-D-GlcpNAc-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                                              beta-D-GlcpNAc-(1->6)-beta-D-Galp-(1->4)-D-Glcp 0
                                              beta-L-Fucp-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                                              beta-lactose + 0
                                              lactobionic acid + 0
                                              lactose 6'-phosphate 0
                                              lactose phosphate + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.