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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:lactose
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Accession:CHEBI:17716 term browser browse the term
Definition:A glycosylglucose disaccharide, found most notably in milk, that consists of D-galactose and D-glucose fragments bonded through a beta-1->4 glycosidic linkage. The glucose fragment can be in either the alpha- or beta-pyranose form, whereas the galactose fragment can only have the beta-pyranose form.
Synonyms:related_synonym: (Gal)1 (Glc)1;   1-beta-D-Galactopyranosyl-4-D-glucopyranose;   4-(beta-D-galactosido)-D-glucose;   4-O-beta-D-galactopyranosyl-D-glucose;   D-lactose;   Formula=C12H22O11;   Galbeta1-4Glc;   InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11?,12+/m1/s1;   InChIKey=GUBGYTABKSRVRQ-QKKXKWKRSA-N;   Lac;   Laktobiose;   Laktose;   Milchzucker;   SMILES=OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O;   WURCS=2.0/2,2,1/[a2122h-1x_1-5][a2112h-1b_1-5]/1-2/a4-b1;   beta-D-Gal-(1->4)-D-Glc;   beta-D-Galp-(1->4)-D-Glcp;   beta-Gal1,4-Glc;   lactobiose;   milk sugar
 alt_id: CHEBI:10296;   CHEBI:10380;   CHEBI:14497;   CHEBI:22460;   CHEBI:22760;   CHEBI:25005;   CHEBI:27755;   CHEBI:613009
 xref: Beilstein:1292745;   CAS:63-42-3;   GlyGen:G74621DY;   GlyTouCan:G74621DY;   Gmelin:882872;   KEGG:C00243;   KEGG:D00046;   KEGG:G10504;   KNApSAcK:C00001136
 xref_mesh: MESH:D007785
 xref: PMID:1292745;   PMID:17329833;   PMID:18300214;   PMID:19053747;   PMID:19846069;   PMID:19913595;   PMID:20094999;   PMID:20503067;   PMID:20699559;   PMID:20873837;   PMID:20961532;   PMID:21403918;   PMID:2432147;   PMID:2456994;   PMID:28690131;   PMID:28807538;   PMID:6194884;   PMID:7574700;   Reaxys:1292745


show annotations for term's descendants           Sort by:
lactose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase decreases activity EXP Lactose results in decreased activity of CAT protein CTD PMID:2539851 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Lgals3 galectin 3 affects binding ISO Lactose binds to LGALS3 protein CTD PMID:17385862 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Sod1 superoxide dismutase 1 decreases activity EXP Lactose results in decreased activity of SOD1 protein CTD PMID:2539851 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19932
    role 19904
      biological role 19902
        biochemical role 19598
          metabolite 19585
            eukaryotic metabolite 19403
              animal metabolite 19268
                mammalian metabolite 19267
                  human metabolite 18779
                    lactose 3
                      2'-fucosyllactose + 0
                      3-(hexadecylsulfonyl)-2-[(hexadecylsulfonyl)methyl]propyl beta-D-galactosyl-(1->4)-beta-D-glucoside 0
                      3-fucosyllactose + 0
                      D-Galp-(1->3)-beta-D-Galp-(1->4)-D-Glcp 0
                      D-Galp-(1->6)-beta-D-Galp-(1->4)-D-Glcp 0
                      alpha-L-Fucp-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                      alpha-lactose + 0
                      beta-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-Glcp 0
                      beta-D-Galp-(1->4)-[alpha-D-Glcp-(1->2)]-D-Glcp 0
                      beta-D-Galp-(1->6)-beta-D-Galp-(1->4)-D-Glcp 0
                      beta-D-Galp6S-(1->4)-D-Glcp 0
                      beta-D-GlcpNAc-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                      beta-D-GlcpNAc-(1->6)-beta-D-Galp-(1->4)-D-Glcp 0
                      beta-L-Fucp-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                      beta-lactose + 0
                      lactobionic acid + 0
                      lactose 6'-phosphate 0
                      lactose phosphate + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19932
    subatomic particle 19930
      composite particle 19930
        hadron 19930
          baryon 19930
            nucleon 19930
              atomic nucleus 19930
                atom 19930
                  main group element atom 19876
                    p-block element atom 19876
                      carbon group element atom 19816
                        carbon atom 19812
                          organic molecular entity 19812
                            heteroorganic entity 19559
                              organochalcogen compound 19317
                                organooxygen compound 19231
                                  carbohydrates and carbohydrate derivatives 15298
                                    carbohydrate 15298
                                      oligosaccharide 623
                                        disaccharide 529
                                          glycosylglucose 217
                                            lactose 3
                                              2'-fucosyllactose + 0
                                              3-(hexadecylsulfonyl)-2-[(hexadecylsulfonyl)methyl]propyl beta-D-galactosyl-(1->4)-beta-D-glucoside 0
                                              3-fucosyllactose + 0
                                              D-Galp-(1->3)-beta-D-Galp-(1->4)-D-Glcp 0
                                              D-Galp-(1->6)-beta-D-Galp-(1->4)-D-Glcp 0
                                              alpha-L-Fucp-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                                              alpha-lactose + 0
                                              beta-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-Glcp 0
                                              beta-D-Galp-(1->4)-[alpha-D-Glcp-(1->2)]-D-Glcp 0
                                              beta-D-Galp-(1->6)-beta-D-Galp-(1->4)-D-Glcp 0
                                              beta-D-Galp6S-(1->4)-D-Glcp 0
                                              beta-D-GlcpNAc-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                                              beta-D-GlcpNAc-(1->6)-beta-D-Galp-(1->4)-D-Glcp 0
                                              beta-L-Fucp-(1->4)-beta-D-Galp-(1->4)-D-Glcp 0
                                              beta-lactose + 0
                                              lactobionic acid + 0
                                              lactose 6'-phosphate 0
                                              lactose phosphate + 0
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