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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:benzenediol
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Accession:CHEBI:17701 term browser browse the term
Synonyms:related_synonym: Formula=C6H6O2;   dihydroxybenzene
 alt_id: CHEBI:13878;   CHEBI:3027
 xref: CAS:12385-08-9;   KEGG:C01785


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hydroquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4galt alpha 1,4-galactosyltransferase (P blood group) decreases expression ISO hydroquinone results in decreased expression of A4GALT mRNA CTD PMID:31256213 NCBI chr 7:124,085,832...124,110,440
Ensembl chr 7:124,085,834...124,089,385
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO hydroquinone results in increased expression of ABCC3 mRNA CTD PMID:31256213 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Ace2 angiotensin I converting enzyme 2 decreases expression ISO hydroquinone results in decreased expression of ACE2 mRNA CTD PMID:31256213 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Adap2 ArfGAP with dual PH domains 2 increases expression ISO hydroquinone results in increased expression of ADAP2 mRNA CTD PMID:31256213 NCBI chr10:67,494,851...67,527,582
Ensembl chr10:67,494,984...67,526,426
JBrowse link
G Adprh ADP-ribosylarginine hydrolase increases expression ISO hydroquinone results in increased expression of ADPRH mRNA CTD PMID:31256213 NCBI chr11:64,861,772...64,868,112
Ensembl chr11:64,861,768...64,868,108
JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein increases expression ISO hydroquinone results in increased expression of ADTRP mRNA CTD PMID:31256213 NCBI chr17:22,619,913...22,688,296
Ensembl chr17:22,619,891...22,688,307
JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO hydroquinone results in increased expression of AEN mRNA CTD PMID:23416264 NCBI chr 1:140,584,328...140,593,749
Ensembl chr 1:140,584,380...140,593,745
JBrowse link
G Afap1 actin filament associated protein 1 decreases expression ISO hydroquinone results in decreased expression of AFAP1 mRNA CTD PMID:31256213 NCBI chr14:79,923,132...80,035,096
Ensembl chr14:79,919,717...79,988,110
JBrowse link
G Aggf1 angiogenic factor with G patch and FHA domains 1 decreases expression ISO hydroquinone results in decreased expression of AGGF1 mRNA CTD PMID:31256213 NCBI chr 2:25,068,804...25,095,429
Ensembl chr 2:25,069,620...25,095,106
JBrowse link
G Ahr aryl hydrocarbon receptor affects localization
multiple interactions
increases expression
ISO
EXP
hydroquinone affects the localization of AHR protein
alpha-naphthoflavone inhibits the reaction [hydroquinone results in increased expression of AHR protein]
CTD PMID:15935814, PMID:29935983 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aifm2 apoptosis inducing factor, mitochondria associated 2 increases expression ISO hydroquinone results in increased expression of AIFM2 mRNA CTD PMID:31256213 NCBI chr20:31,329,047...31,353,548
Ensembl chr20:31,339,787...31,352,906
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 decreases expression ISO hydroquinone results in decreased expression of AKR1B10 mRNA CTD PMID:31256213 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:17464197 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin multiple interactions ISO ALB protein binds to and affects the transport of hydroquinone CTD PMID:8831264 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 increases expression ISO hydroquinone results in increased expression of ALDH1L2 mRNA CTD PMID:31256213 NCBI chr 7:26,375,866...26,425,838
Ensembl chr 7:26,375,866...26,425,108
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases expression ISO hydroquinone results in increased expression of ALDH2 mRNA CTD PMID:15452088 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO hydroquinone results in increased expression of ALDH3A1 mRNA CTD PMID:31256213 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type increases expression ISO hydroquinone results in increased expression of ALOX12 mRNA CTD PMID:31256213 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type increases expression ISO hydroquinone results in increased expression of ALOX12B mRNA CTD PMID:31256213 NCBI chr10:55,744,646...55,756,524
Ensembl chr10:55,744,588...55,756,566
JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 increases expression ISO hydroquinone results in increased expression of ALOXE3 mRNA CTD PMID:31256213 NCBI chr10:55,711,996...55,735,915
Ensembl chr10:55,712,043...55,735,911
JBrowse link
G Alpk1 alpha-kinase 1 increases expression ISO hydroquinone results in increased expression of ALPK1 mRNA CTD PMID:31256213 NCBI chr 2:231,997,360...232,117,471
Ensembl chr 2:231,996,088...232,117,134
JBrowse link
G Ankdd1a ankyrin repeat and death domain containing 1A decreases expression ISO hydroquinone results in decreased expression of ANKDD1A mRNA CTD PMID:31256213 NCBI chr 8:71,034,630...71,057,265
Ensembl chr 8:71,035,309...71,055,969
JBrowse link
G Anxa1 annexin A1 increases expression ISO hydroquinone results in increased expression of ANXA1 mRNA CTD PMID:31256213 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Anxa3 annexin A3 increases expression ISO hydroquinone results in increased expression of ANXA3 mRNA CTD PMID:31256213 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression ISO hydroquinone results in decreased expression of AQP3 mRNA CTD PMID:31256213 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Arg1 arginase 1 increases expression ISO hydroquinone results in increased expression of ARG1 mRNA CTD PMID:31256213 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arg2 arginase 2 increases expression ISO hydroquinone results in increased expression of ARG2 mRNA CTD PMID:31256213 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Arhgap27 Rho GTPase activating protein 27 increases expression ISO hydroquinone results in increased expression of ARHGAP27 mRNA CTD PMID:31256213 NCBI chr10:91,418,535...91,451,831
Ensembl chr10:91,419,912...91,448,477
JBrowse link
G Arhgap42 Rho GTPase activating protein 42 decreases expression ISO hydroquinone results in decreased expression of ARHGAP42 mRNA CTD PMID:31256213 NCBI chr 8:7,210,999...7,446,215
Ensembl chr 8:7,213,822...7,426,611
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha affects expression ISO hydroquinone affects the expression of ARHGDIA protein CTD PMID:17181942 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 increases expression ISO hydroquinone results in increased expression of ARHGEF2 mRNA CTD PMID:31256213 NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377
JBrowse link
G Arhgef26 Rho guanine nucleotide exchange factor 26 decreases expression ISO hydroquinone results in decreased expression of ARHGEF26 mRNA CTD PMID:31256213 NCBI chr 2:27,107,263...27,236,336
Ensembl chr 2:27,107,318...27,236,672
JBrowse link
G Arl3 ADP ribosylation factor like GTPase 3 decreases expression ISO hydroquinone results in decreased expression of ARL3 mRNA CTD PMID:31256213 NCBI chr 1:266,287,015...266,333,099
Ensembl chr 1:266,287,017...266,333,105
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO hydroquinone results in increased expression of ASNS mRNA CTD PMID:31256213 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Asprv1 aspartic peptidase, retroviral-like 1 increases expression ISO hydroquinone results in increased expression of ASPRV1 mRNA CTD PMID:31256213 NCBI chr 4:118,431,755...118,433,286
Ensembl chr 4:118,431,755...118,432,775
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO hydroquinone results in increased expression of ATF3 mRNA CTD PMID:31256213 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO hydroquinone results in increased expression of ATF4 mRNA CTD PMID:15452088 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atg5 autophagy related 5 multiple interactions
increases expression
ISO PARP1 protein promotes the reaction [hydroquinone results in increased expression of ATG5 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of ATG5 mRNA] CTD PMID:28263894 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Atp2c2 ATPase secretory pathway Ca2+ transporting 2 increases expression ISO hydroquinone results in increased expression of ATP2C2 mRNA CTD PMID:31256213 NCBI chr19:52,347,480...52,404,608
Ensembl chr19:52,347,580...52,404,607
JBrowse link
G Atp6v1c2 ATPase H+ transporting V1 subunit C2 increases expression ISO hydroquinone results in increased expression of ATP6V1C2 mRNA CTD PMID:31256213 NCBI chr 6:42,585,452...42,632,289
Ensembl chr 6:42,585,934...42,630,983
JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding increases expression ISO hydroquinone results in increased expression of AZGP1 mRNA CTD PMID:31256213 NCBI chr12:19,196,565...19,203,094
Ensembl chr12:19,196,611...19,202,647
JBrowse link
G Bach1 BTB domain and CNC homolog 1 multiple interactions
affects localization
ISO [ferric chloride results in increased oxidation of hydroquinone] promotes the reaction [hydroquinone analog binds to BACH1 protein]; hydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]
hydroquinone affects the localization of BACH1 protein
CTD PMID:28645578 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842
JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression ISO hydroquinone results in decreased expression of BAD mRNA CTD PMID:15452088 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bag1 BAG cochaperone 1 decreases expression ISO hydroquinone results in decreased expression of BAG1 mRNA CTD PMID:31256213 NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor increases expression ISO hydroquinone results in increased expression of BAMBI mRNA CTD PMID:31256213 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO hydroquinone results in increased expression of BBC3 mRNA CTD PMID:23416264 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl11a BAF chromatin remodeling complex subunit BCL11A decreases expression ISO hydroquinone results in decreased expression of BCL11A mRNA CTD PMID:31256213 NCBI chr14:108,826,717...108,921,197
Ensembl chr14:108,826,831...108,921,669
JBrowse link
G Bcl11b BAF chromatin remodeling complex subunit BCL11B decreases expression ISO hydroquinone results in decreased expression of BCL11B mRNA CTD PMID:31256213 NCBI chr 6:131,834,097...131,927,251
Ensembl chr 6:131,834,097...131,926,272
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of BCL2 protein CTD PMID:28444915 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 decreases expression ISO hydroquinone results in decreased expression of BDH2 mRNA CTD PMID:31256213 NCBI chr 2:240,461,505...240,482,149
Ensembl chr 2:240,461,505...240,482,145
JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions
ISO hydroquinone results in increased expression of BECN1 mRNA; hydroquinone results in increased expression of BECN1 protein
PARP1 protein promotes the reaction [hydroquinone results in increased expression of BECN1 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of BECN1 mRNA]
CTD PMID:28263894 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression
decreases expression
ISO hydroquinone results in increased expression of BIRC3 mRNA
hydroquinone results in decreased expression of BIRC3 mRNA
CTD PMID:15452088, PMID:31256213 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression
multiple interactions
ISO hydroquinone results in decreased expression of BIRC5 protein
Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of BIRC5 protein]
CTD PMID:28886972 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO hydroquinone results in decreased expression of BNIP3 mRNA CTD PMID:15452088 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Bora bora, aurora kinase A activator decreases expression ISO hydroquinone results in decreased expression of BORA mRNA CTD PMID:23416264 NCBI chr15:83,442,217...83,463,737
Ensembl chr15:83,442,144...83,463,717
JBrowse link
G Bpifc BPI fold containing family C increases expression ISO hydroquinone results in increased expression of BPIFC mRNA CTD PMID:31256213 NCBI chr 7:23,854,846...23,911,953
Ensembl chr 7:23,854,846...23,911,953
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO hydroquinone results in increased expression of BRCA1 protein CTD PMID:29421518 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression ISO hydroquinone results in decreased expression of BST2 mRNA CTD PMID:31256213 NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO hydroquinone results in increased expression of BTG2 mRNA CTD PMID:23416264 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Bub3 BUB3 mitotic checkpoint protein decreases expression ISO hydroquinone results in decreased expression of BUB3 mRNA CTD PMID:31256213 NCBI chr 1:203,526,853...203,537,459
Ensembl chr 1:203,524,426...203,557,337
JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression ISO hydroquinone results in decreased expression of CA3 mRNA CTD PMID:31256213 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Ca9 carbonic anhydrase 9 decreases expression ISO hydroquinone results in decreased expression of CA9 mRNA CTD PMID:31256213 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Calb2 calbindin 2 increases expression ISO hydroquinone results in increased expression of CALB2 mRNA CTD PMID:31256213 NCBI chr19:41,482,743...41,509,617
Ensembl chr19:41,482,728...41,509,658
JBrowse link
G Calcb calcitonin-related polypeptide, beta increases expression ISO hydroquinone results in increased expression of CALCB mRNA CTD PMID:31256213 NCBI chr 1:184,271,116...184,276,480
Ensembl chr 1:184,271,590...184,276,475
JBrowse link
G Calhm6 calcium homeostasis modulator family member 6 decreases expression ISO hydroquinone results in decreased expression of CALHM6 mRNA CTD PMID:31256213 NCBI chr20:27,681,138...27,683,580
Ensembl chr20:27,681,036...27,682,861
JBrowse link
G Calml3 calmodulin-like 3 decreases expression ISO hydroquinone results in decreased expression of CALML3 mRNA CTD PMID:31256213 NCBI chr17:70,070,458...70,073,697
Ensembl chr17:70,072,156...70,073,530
JBrowse link
G Capn2 calpain 2 decreases activity ISO hydroquinone results in decreased activity of CAPN2 protein CTD PMID:9118890 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
increases cleavage
decreases activity
decreases expression
ISO [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of and affects the activity of CASP3 protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of CASP3 protein]; IGF1 protein inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]
hydroquinone results in increased cleavage of CASP3 protein
hydroquinone results in decreased activity of CASP3 protein
[hydroquinone results in increased abundance of Reactive Oxygen Species] which results in decreased activity of CASP3 protein
hydroquinone results in decreased expression of CASP3 mRNA
CTD PMID:15337166, PMID:15452088, PMID:15777082, PMID:15816534, PMID:20946948, PMID:22302391, PMID:22960397, PMID:23776099, PMID:28444915, PMID:28886972 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 decreases expression ISO hydroquinone results in decreased expression of CASP6 mRNA CTD PMID:15452088 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp7 caspase 7 increases cleavage
increases expression
decreases activity
multiple interactions
ISO hydroquinone results in increased cleavage of CASP7 protein
hydroquinone results in increased expression of CASP7 protein modified form
hydroquinone results in decreased activity of CASP7 protein
Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP7 protein modified form]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of CASP7 protein]
CTD PMID:19064679, PMID:22960397, PMID:28886972 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity
ISO MPO protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]
hydroquinone results in increased activity of CASP8 protein
CTD PMID:15777082, PMID:23776099 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 decreases expression
multiple interactions
increases expression
increases activity
increases cleavage
ISO hydroquinone results in decreased expression of CASP9 mRNA
Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP9 protein modified form]
hydroquinone results in increased activity of CASP9 protein
hydroquinone results in increased cleavage of CASP9 protein
CTD PMID:15452088, PMID:15777082, PMID:15816534, PMID:20946948, PMID:22302391, PMID:23776099, PMID:28886972 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase decreases response to substance ISO CAT protein results in decreased susceptibility to hydroquinone CTD PMID:10193577 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression ISO hydroquinone results in decreased expression of CAVIN2 mRNA CTD PMID:31256213 NCBI chr 9:55,244,136...55,256,153
Ensembl chr 9:55,243,255...55,256,340
JBrowse link
G Cbs cystathionine beta synthase increases expression ISO hydroquinone results in increased expression of CBS mRNA CTD PMID:31256213 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
JBrowse link
G Ccdc127 coiled-coil domain containing 127 decreases expression ISO hydroquinone results in decreased expression of CCDC127 mRNA CTD PMID:31256213 NCBI chr 1:31,538,088...31,545,573
Ensembl chr 1:31,539,215...31,545,559
JBrowse link
G Ccdc163 coiled-coil domain containing 163 decreases expression ISO hydroquinone results in decreased expression of CCDC163 mRNA CTD PMID:31256213 NCBI chr 5:135,562,034...135,568,067
Ensembl chr 5:135,562,034...135,568,062
JBrowse link
G Ccdc8 coiled-coil domain containing 8 decreases expression ISO hydroquinone results in decreased expression of CCDC8 mRNA CTD PMID:31256213 NCBI chr 1:78,933,372...78,936,700
Ensembl chr 1:78,933,372...78,936,700
JBrowse link
G Ccdc88c coiled-coil domain containing 88C decreases expression ISO hydroquinone results in decreased expression of CCDC88C mRNA CTD PMID:31256213 NCBI chr 6:124,905,811...125,028,011
Ensembl chr 6:124,905,808...125,027,553
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression ISO hydroquinone results in increased expression of CCL11 protein CTD PMID:17572062 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases secretion
decreases expression
multiple interactions
increases secretion
increases expression
ISO hydroquinone results in decreased secretion of CCL2 protein
hydroquinone results in decreased expression of CCL2 mRNA
hydroquinone inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of CCL2 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of CCL2 protein]
hydroquinone results in increased secretion of CCL2 protein
hydroquinone results in increased expression of CCL2 protein
CTD PMID:17572062, PMID:20946948, PMID:22302391, PMID:22465845 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO hydroquinone results in increased expression of CCL3 protein CTD PMID:17572062 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO hydroquinone results in increased expression of CCL4 protein CTD PMID:17572062, PMID:18353026 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO hydroquinone results in increased expression of CCL5 protein CTD PMID:17572062 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccn1 cellular communication network factor 1 affects expression ISO hydroquinone affects the expression of CCN1 mRNA CTD PMID:15452088 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression ISO hydroquinone results in increased expression of CCN2 mRNA CTD PMID:31256213 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccna1 cyclin A1 increases expression ISO hydroquinone results in increased expression of CCNA1 mRNA CTD PMID:31256213 NCBI chr 2:144,456,689...144,503,570
Ensembl chr 2:144,458,153...144,467,912
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CCND1 protein] CTD PMID:28886972 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne2 cyclin E2 increases expression ISO hydroquinone results in increased expression of CCNE2 mRNA CTD PMID:23416264 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccnf cyclin F decreases expression ISO hydroquinone results in decreased expression of CCNF mRNA CTD PMID:23416264 NCBI chr10:13,594,687...13,619,935
Ensembl chr10:13,594,687...13,619,935
JBrowse link
G Ccsap centriole, cilia and spindle-associated protein decreases expression ISO hydroquinone results in decreased expression of CCSAP mRNA CTD PMID:31256213 NCBI chr19:56,615,326...56,634,031
Ensembl chr19:56,617,399...56,633,633
JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD69 protein] CTD PMID:20054000 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein] CTD PMID:19148301 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
JBrowse link
G Cd86 CD86 molecule increases expression
multiple interactions
ISO hydroquinone results in increased expression of CD86 protein
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 protein]
CTD PMID:19148301, PMID:19665512 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression ISO hydroquinone results in decreased expression of CDCA2 mRNA CTD PMID:23416264 NCBI chr15:44,365,396...44,411,601
Ensembl chr15:44,365,405...44,411,004
JBrowse link
G Cdca7 cell division cycle associated 7 decreases expression ISO hydroquinone results in decreased expression of CDCA7 mRNA CTD PMID:31256213 NCBI chr 3:59,153,281...59,163,916
Ensembl chr 3:59,153,280...59,163,913
JBrowse link
G Cdh26 cadherin 26 decreases expression ISO hydroquinone results in decreased expression of CDH26 mRNA CTD PMID:31256213 NCBI chr 3:173,969,004...174,020,867
Ensembl chr 3:173,969,273...174,019,766
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO hydroquinone results in increased expression of CDKN1A mRNA CTD PMID:23416264 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO hydroquinone results in decreased expression of CDKN1C mRNA CTD PMID:31256213 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Cdsn corneodesmosin increases expression ISO hydroquinone results in increased expression of CDSN mRNA CTD PMID:31256213 NCBI chr20:3,704,626...3,707,266 JBrowse link
G Cemip cell migration inducing hyaluronidase increases expression ISO hydroquinone results in increased expression of CEMIP mRNA CTD PMID:31256213 NCBI chr 1:146,069,774...146,226,320
Ensembl chr 1:146,069,771...146,226,462
JBrowse link
G Cenpa centromere protein A decreases expression ISO hydroquinone results in decreased expression of CENPA mRNA CTD PMID:23416264 NCBI chr 6:27,072,259...27,080,863
Ensembl chr 6:27,072,166...27,080,856
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO hydroquinone results in increased expression of CES1 mRNA CTD PMID:31256213 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cfap44 cilia and flagella associated protein 44 decreases expression ISO hydroquinone results in decreased expression of CFAP44 mRNA CTD PMID:31256213 NCBI chr11:61,160,793...61,237,056
Ensembl chr11:61,162,628...61,234,944
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO hydroquinone results in increased expression of CFLAR mRNA CTD PMID:31256213 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Ch25h cholesterol 25-hydroxylase increases expression ISO hydroquinone results in increased expression of CH25H mRNA CTD PMID:31256213 NCBI chr 1:252,807,062...252,811,409
Ensembl chr 1:252,807,065...252,808,380
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO hydroquinone results in increased expression of CHAC1 mRNA CTD PMID:31256213 NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425
JBrowse link
G Chp2 calcineurin-like EF hand protein 2 decreases expression ISO hydroquinone results in decreased expression of CHP2 mRNA CTD PMID:31256213 NCBI chr 1:192,169,634...192,173,228
Ensembl chr 1:192,169,841...192,173,253
JBrowse link
G Chst2 carbohydrate sulfotransferase 2 increases expression ISO hydroquinone results in increased expression of CHST2 mRNA CTD PMID:31256213 NCBI chr 8:103,186,759...103,190,612
Ensembl chr 8:103,188,651...103,190,243
JBrowse link
G Clca4 chloride channel accessory 4 decreases expression ISO hydroquinone results in decreased expression of CLCA4 mRNA CTD PMID:31256213 NCBI chr 2:250,842,939...250,864,060
Ensembl chr 2:250,843,165...250,862,419
JBrowse link
G Cldn8 claudin 8 decreases expression ISO hydroquinone results in decreased expression of CLDN8 mRNA CTD PMID:31256213 NCBI chr11:28,525,641...28,527,890
Ensembl chr11:28,525,643...28,527,890
JBrowse link
G Clic3 chloride intracellular channel 3 increases expression ISO hydroquinone results in increased expression of CLIC3 mRNA CTD PMID:31256213 NCBI chr 3:2,675,732...2,678,248
Ensembl chr 3:2,676,296...2,680,565
JBrowse link
G Clmp CXADR-like membrane protein increases expression ISO hydroquinone results in increased expression of CLMP mRNA CTD PMID:31256213 NCBI chr 8:44,846,685...44,975,460
Ensembl chr 8:44,847,157...44,975,457
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 decreases expression ISO hydroquinone results in decreased expression of CMPK2 mRNA CTD PMID:31256213 NCBI chr 6:45,683,242...45,694,824
Ensembl chr 6:45,683,234...45,694,822
JBrowse link
G Cnfn cornifelin increases expression ISO hydroquinone results in increased expression of CNFN mRNA CTD PMID:31256213 NCBI chr 1:82,234,032...82,236,602
Ensembl chr 1:82,234,032...82,236,179
JBrowse link
G Cnmd chondromodulin increases response to substance
increases expression
multiple interactions
ISO CNMD protein results in increased susceptibility to hydroquinone
hydroquinone results in increased expression of CNMD mRNA
Dactinomycin inhibits the reaction [hydroquinone results in increased expression of CNMD protein]; hydroquinone results in increased expression of and results in increased secretion of CNMD protein; NQO1 protein inhibits the reaction [CNMD protein results in increased susceptibility to hydroquinone]; NQO1 protein inhibits the reaction [hydroquinone results in increased expression of CNMD protein]
CTD PMID:19525446 NCBI chr15:61,923,291...61,947,840
Ensembl chr15:61,923,299...61,947,764
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression
multiple interactions
ISO hydroquinone results in increased expression of COL1A1 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]
CTD PMID:18055817 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased expression of and results in increased secretion of TNF protein; [COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased secretion of IL1B protein; [COL2A1 protein co-treated with hydroquinone] results in increased expression of IL6 protein CTD PMID:29908986, PMID:29935983 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression
increases expression
multiple interactions
ISO hydroquinone results in decreased expression of COL4A1 mRNA
hydroquinone results in increased expression of COL4A1 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]
CTD PMID:18055817 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Col5a2 collagen type V alpha 2 chain decreases expression ISO hydroquinone results in decreased expression of COL5A2 mRNA CTD PMID:31256213 NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
JBrowse link
G Crct1 cysteine-rich C-terminal 1 increases expression ISO hydroquinone results in increased expression of CRCT1 mRNA CTD PMID:31256213 Ensembl chr 2:193,330,397...193,330,699 JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 increases expression ISO hydroquinone results in increased expression of CRISPLD2 mRNA CTD PMID:31256213 NCBI chr19:52,647,038...52,705,118
Ensembl chr19:52,647,070...52,705,131
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO hydroquinone promotes the reaction [[CSF1R protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK3 protein
hydroquinone promotes the reaction [[CSF2 protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide]
CTD PMID:7884313, PMID:15129224 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 increases expression ISO hydroquinone results in increased expression of CSGALNACT1 mRNA CTD PMID:31256213 NCBI chr16:22,704,318...23,075,071
Ensembl chr16:22,979,444...23,074,798
JBrowse link
G Csrnp3 cysteine and serine rich nuclear protein 3 decreases expression ISO hydroquinone results in decreased expression of CSRNP3 mRNA CTD PMID:31256213 NCBI chr 3:51,883,559...52,120,290
Ensembl chr 3:51,883,559...52,120,290
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression ISO hydroquinone results in decreased expression of CSRP2 mRNA CTD PMID:31256213 NCBI chr 7:53,630,675...53,649,309
Ensembl chr 7:53,630,621...53,649,310
JBrowse link
G Cst6 cystatin E/M increases expression ISO hydroquinone results in increased expression of CST6 mRNA CTD PMID:31256213 NCBI chr 1:220,727,292...220,729,000
Ensembl chr 1:220,727,292...220,729,000
JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO hydroquinone results in increased expression of CTH mRNA CTD PMID:31256213 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
affects localization
decreases expression
ISO hydroquinone inhibits the reaction [CTNNB1 protein binds to LEF1 protein]; hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein; IGF1 protein inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein] CTD PMID:28886972, PMID:30567741 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO hydroquinone results in decreased expression of CXCL12 mRNA CTD PMID:22960397 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cycs cytochrome c, somatic affects localization ISO hydroquinone affects the localization of CYCS protein CTD PMID:15777082, PMID:15816534 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects response to substance
increases expression
ISO CYP1A1 protein affects the susceptibility to hydroquinone
hydroquinone results in increased expression of CYP1A1 mRNA
CTD PMID:8242868, PMID:23416264, PMID:31256213 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO hydroquinone results in increased expression of CYP1B1 mRNA CTD PMID:23416264, PMID:31256213 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP [CYP2B1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone CTD PMID:8211999 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects response to substance ISO CYP2B1 protein affects the susceptibility to hydroquinone CTD PMID:8242868 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions ISO [CYP2D6 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone CTD PMID:21402134 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression
EXP
ISO
[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone; [CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone; [Glutathione co-treated with [CYP2E1 protein results in increased metabolism of Phenol]] results in increased chemical synthesis of [Glutathione binds to hydroquinone metabolite]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone]
hydroquinone results in increased expression of CYP2E1 mRNA; hydroquinone results in increased expression of CYP2E1 protein
[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroquinone; PPP2CA protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein]
CTD PMID:8211999, PMID:15051535, PMID:30567741 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO [CYP3A5 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone CTD PMID:21402134 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases expression ISO hydroquinone results in increased expression of CYP4F18 mRNA CTD PMID:23940708 NCBI chr16:19,501,680...19,528,935
Ensembl chr16:19,410,810...19,528,999
JBrowse link
G Cysrt1 cysteine rich tail 1 increases expression ISO hydroquinone results in increased expression of CYSRT1 mRNA CTD PMID:31256213 NCBI chr 3:2,458,295...2,462,037
Ensembl chr 3:2,458,295...2,459,385
JBrowse link
G Dap death-associated protein decreases expression ISO hydroquinone results in decreased expression of DAP mRNA CTD PMID:15452088 NCBI chr 2:84,275,884...84,328,998
Ensembl chr 2:84,275,884...84,328,998
JBrowse link
G Dapl1 death associated protein-like 1 decreases expression ISO hydroquinone results in decreased expression of DAPL1 mRNA CTD PMID:31256213 NCBI chr 3:45,538,408...45,559,281
Ensembl chr 3:45,538,797...45,559,331
JBrowse link
G Dapp1 dual adaptor of phosphotyrosine and 3-phosphoinositides 1 increases expression ISO hydroquinone results in increased expression of DAPP1 mRNA CTD PMID:31256213 NCBI chr 2:243,175,346...243,224,883
Ensembl chr 2:243,175,346...243,224,883
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 decreases expression ISO hydroquinone results in decreased expression of DBT mRNA CTD PMID:31256213 NCBI chr 2:219,563,783...219,592,651
Ensembl chr 2:219,563,783...219,592,650
JBrowse link
G Dcun1d3 defective in cullin neddylation 1 domain containing 3 increases expression ISO hydroquinone results in increased expression of DCUN1D3 mRNA CTD PMID:31256213 NCBI chr 1:189,626,442...189,666,440
Ensembl chr 1:189,627,972...189,666,440
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression ISO hydroquinone results in decreased expression of DDAH1 mRNA CTD PMID:31256213 NCBI chr 2:251,634,368...251,766,009
Ensembl chr 2:251,634,431...251,766,014
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO hydroquinone results in increased expression of DDIT3 mRNA CTD PMID:23416264, PMID:31256213 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO hydroquinone results in increased expression of DDIT4 mRNA CTD PMID:23416264 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Depdc7 DEP domain containing 7 decreases expression ISO hydroquinone results in decreased expression of DEPDC7 mRNA CTD PMID:31256213 NCBI chr 3:94,665,714...94,687,013
Ensembl chr 3:94,665,717...94,686,989
JBrowse link
G Dffb DNA fragmentation factor subunit beta decreases expression ISO hydroquinone results in decreased expression of DFFB mRNA CTD PMID:31256213 NCBI chr 5:171,250,559...171,261,875
Ensembl chr 5:171,249,633...171,262,119
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 affects expression ISO hydroquinone affects the expression of DKK1 mRNA CTD PMID:22960397 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 increases expression ISO hydroquinone results in increased expression of DNAJA1 mRNA CTD PMID:15452088 NCBI chr 5:57,028,467...57,039,378
Ensembl chr 5:57,028,467...57,039,378
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO hydroquinone results in increased expression of DNAJB1 mRNA CTD PMID:15452088 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Dner delta/notch-like EGF repeat containing decreases expression ISO hydroquinone results in decreased expression of DNER mRNA CTD PMID:31256213 NCBI chr 9:91,965,866...92,291,172
Ensembl chr 9:91,965,866...92,291,220
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression
affects expression
ISO hydroquinone results in decreased expression of DNMT1 mRNA; hydroquinone results in decreased expression of DNMT1 protein
hydroquinone affects the expression of DNMT1 mRNA
CTD PMID:22245671, PMID:27979589, PMID:31899212 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression
increases expression
ISO hydroquinone results in decreased expression of DNMT3A mRNA; hydroquinone results in decreased expression of DNMT3A protein
hydroquinone results in increased expression of DNMT3A mRNA
CTD PMID:22245671, PMID:27979589, PMID:31899212 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression
multiple interactions
affects expression
ISO hydroquinone results in decreased expression of DNMT3B mRNA
Decitabine affects the reaction [hydroquinone affects the expression of DNMT3B mRNA]; trichostatin A affects the reaction [hydroquinone affects the expression of DNMT3B mRNA]
CTD PMID:22245671, PMID:31899212 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L decreases expression ISO hydroquinone results in decreased expression of DTX3L mRNA CTD PMID:31256213 NCBI chr11:67,758,093...67,767,623
NCBI chr11:67,768,542...67,772,428
Ensembl chr11:67,757,928...67,767,622
JBrowse link
G Dusp19 dual specificity phosphatase 19 decreases expression ISO hydroquinone results in decreased expression of DUSP19 mRNA CTD PMID:31256213 NCBI chr 3:67,849,966...67,862,475
Ensembl chr 3:67,849,966...67,862,475
JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression ISO hydroquinone results in increased expression of DUSP5 mRNA CTD PMID:31256213 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO hydroquinone results in increased expression of DUSP6 mRNA CTD PMID:31256213 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Dzip1 DAZ interacting zinc finger protein 1 decreases expression ISO hydroquinone results in decreased expression of DZIP1 mRNA CTD PMID:31256213 NCBI chr15:104,117,551...104,168,574
Ensembl chr15:104,117,556...104,170,958
JBrowse link
G E4f1 E4F transcription factor 1 increases expression
affects response to substance
multiple interactions
ISO hydroquinone results in increased expression of E4F1 mRNA; hydroquinone results in increased expression of E4F1 protein
E4F1 protein affects the susceptibility to hydroquinone
[E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of H2AX protein modified form; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein modified form
CTD PMID:30448557, PMID:30506647 NCBI chr10:13,812,335...13,835,847
Ensembl chr10:13,815,293...13,826,945
JBrowse link
G Ecm2 extracellular matrix protein 2 increases expression ISO hydroquinone results in increased expression of ECM2 mRNA CTD PMID:31256213 NCBI chr17:15,533,760...15,566,403
Ensembl chr17:15,533,972...15,566,332
JBrowse link
G Edn1 endothelin 1 decreases expression ISO hydroquinone results in decreased expression of EDN1 mRNA CTD PMID:31256213 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Edn2 endothelin 2 decreases expression ISO hydroquinone results in decreased expression of EDN2 mRNA CTD PMID:31256213 NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase decreases expression ISO hydroquinone results in decreased expression of EEF2K mRNA CTD PMID:31256213 NCBI chr 1:190,780,211...190,839,926
Ensembl chr 1:190,780,236...190,842,324
JBrowse link
G Efna1 ephrin A1 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of EFNA1 mRNA CTD PMID:32198055 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
JBrowse link
G Egr3 early growth response 3 increases expression ISO hydroquinone results in increased expression of EGR3 mRNA CTD PMID:31256213 NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 decreases expression ISO hydroquinone results in decreased expression of EHMT2 protein CTD PMID:27979589 NCBI chr20:4,576,033...4,592,980
Ensembl chr20:4,576,057...4,592,980
JBrowse link
G Eid3 EP300 interacting inhibitor of differentiation 3 decreases expression ISO hydroquinone results in decreased expression of EID3 mRNA CTD PMID:31256213 NCBI chr 7:26,976,154...26,977,479 JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression ISO hydroquinone results in increased expression of EIF4EBP1 mRNA CTD PMID:31256213 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Elf3 E74 like ETS transcription factor 3 increases expression ISO hydroquinone results in increased expression of ELF3 mRNA CTD PMID:23416264 NCBI chr13:52,083,873...52,088,798
Ensembl chr13:52,083,859...52,088,780
JBrowse link
G Elf5 E74 like ETS transcription factor 5 increases expression ISO hydroquinone results in increased expression of ELF5 mRNA CTD PMID:31256213 NCBI chr 3:93,333,514...93,374,454
Ensembl chr 3:93,351,619...93,371,656
JBrowse link
G Elmod1 ELMO domain containing 1 increases expression ISO hydroquinone results in increased expression of ELMOD1 mRNA CTD PMID:31256213 NCBI chr 8:58,486,078...58,542,884
Ensembl chr 8:58,486,078...58,542,844
JBrowse link
G Elovl4 ELOVL fatty acid elongase 4 increases expression ISO hydroquinone results in increased expression of ELOVL4 mRNA CTD PMID:31256213 NCBI chr 8:91,310,690...91,338,625
Ensembl chr 8:91,310,630...91,338,843
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression ISO hydroquinone results in decreased expression of ELOVL5 mRNA CTD PMID:31256213 NCBI chr 8:85,220,941...85,287,449
Ensembl chr 8:85,259,982...85,285,983
JBrowse link
G Elp2 elongator acetyltransferase complex subunit 2 decreases expression ISO hydroquinone results in decreased expression of ELP2 mRNA CTD PMID:31256213 NCBI chr18:16,544,515...16,581,086
Ensembl chr18:16,544,508...16,581,116
JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 increases expression ISO hydroquinone results in increased expression of EPB41L3 mRNA CTD PMID:31256213 NCBI chr 9:117,314,935...117,666,408
Ensembl chr 9:117,538,009...117,666,410
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions EXP EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone] CTD PMID:8211999 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Eps8l1 EPS8-like 1 increases expression ISO hydroquinone results in increased expression of EPS8L1 mRNA CTD PMID:31256213 NCBI chr 1:72,926,106...72,942,433
Ensembl chr 1:72,927,151...72,941,869
JBrowse link
G Ereg epiregulin increases expression ISO hydroquinone results in increased expression of EREG mRNA CTD PMID:31256213 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Erich5 glutamate-rich 5 decreases expression ISO hydroquinone results in decreased expression of ERICH5 mRNA CTD PMID:31256213 NCBI chr 7:73,222,331...73,243,684
Ensembl chr 7:73,222,730...73,242,899
JBrowse link
G Esr1 estrogen receptor 1 decreases expression ISO hydroquinone results in decreased expression of ESR1 mRNA CTD PMID:31256213 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Etv4 ETS variant transcription factor 4 increases expression ISO hydroquinone results in increased expression of ETV4 mRNA CTD PMID:31256213 NCBI chr10:89,685,058...89,700,300
Ensembl chr10:89,685,058...89,700,283
JBrowse link
G Exosc3 exosome component 3 decreases expression ISO hydroquinone results in decreased expression of EXOSC3 mRNA CTD PMID:31256213 NCBI chr 5:60,866,498...60,871,734
Ensembl chr 5:60,868,502...60,871,705
JBrowse link
G Exosc6 exosome component 6 increases expression ISO hydroquinone results in increased expression of EXOSC6 mRNA CTD PMID:31256213 NCBI chr19:43,190,879...43,193,164
Ensembl chr19:43,191,390...43,192,208
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO hydroquinone results in decreased expression of EZH2 protein CTD PMID:27979589 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO hydroquinone results in decreased expression of F2R mRNA CTD PMID:31256213 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G Fadd Fas associated via death domain decreases expression ISO hydroquinone results in decreased expression of FADD mRNA CTD PMID:15452088 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fam117b family with sequence similarity 117, member B decreases expression ISO hydroquinone results in decreased expression of FAM117B mRNA CTD PMID:31256213 NCBI chr 9:66,716,969...66,784,487
Ensembl chr 9:66,716,969...66,784,487
JBrowse link
G Fam13a family with sequence similarity 13, member A decreases expression ISO hydroquinone results in decreased expression of FAM13A mRNA CTD PMID:31256213 NCBI chr 4:89,183,180...89,281,282
Ensembl chr 4:89,183,768...89,281,222
JBrowse link
G Fam43a family with sequence similarity 43, member A increases expression ISO hydroquinone results in increased expression of FAM43A mRNA CTD PMID:31256213 NCBI chr11:73,676,601...73,679,003
Ensembl chr11:73,676,601...73,678,984
JBrowse link
G Fam83d family with sequence similarity 83, member D decreases expression ISO hydroquinone results in decreased expression of FAM83D mRNA CTD PMID:23416264 NCBI chr 3:155,269,344...155,288,612
Ensembl chr 3:155,269,347...155,288,533
JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions
ISO hydroquinone results in increased expression of FAS protein
[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of FAS protein
CTD PMID:23776099, PMID:28444915 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression ISO hydroquinone results in increased expression of FASLG protein CTD PMID:23776099 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO hydroquinone results in decreased expression of FBXO5 mRNA CTD PMID:23416264 NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 decreases expression ISO hydroquinone results in decreased expression of FGFR3 mRNA CTD PMID:31256213 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706
JBrowse link
G Fibin fin bud initiation factor homolog increases expression ISO hydroquinone results in increased expression of FIBIN mRNA CTD PMID:31256213 NCBI chr 3:101,545,207...101,547,478
Ensembl chr 3:101,545,208...101,547,478
JBrowse link
G Fn1 fibronectin 1 affects expression ISO hydroquinone affects the expression of FN1 mRNA CTD PMID:15452088 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO hydroquinone results in decreased expression of FOS mRNA CTD PMID:15452088 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO hydroquinone results in increased expression of FOSL1 mRNA CTD PMID:31256213 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Fry FRY microtubule binding protein increases expression ISO hydroquinone results in increased expression of FRY mRNA CTD PMID:31256213 NCBI chr12:5,573,729...5,822,874
Ensembl chr12:5,573,729...5,822,874
JBrowse link
G Fsip1 fibrous sheath interacting protein 1 increases expression ISO hydroquinone results in increased expression of FSIP1 mRNA CTD PMID:31256213 NCBI chr 3:109,877,943...110,021,186
Ensembl chr 3:109,969,152...110,021,149
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO hydroquinone results in increased expression of FTH1 mRNA CTD PMID:15452088 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Fzd2 frizzled class receptor 2 decreases expression ISO hydroquinone results in decreased expression of FZD2 mRNA CTD PMID:31256213 NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
JBrowse link
G G0s2 G0/G1switch 2 increases expression ISO hydroquinone results in increased expression of G0S2 mRNA CTD PMID:31256213 NCBI chr13:112,004,140...112,005,052
Ensembl chr13:112,004,140...112,005,052
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO hydroquinone results in increased expression of GADD45A mRNA CTD PMID:23416264 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gas1 growth arrest-specific 1 decreases expression ISO hydroquinone results in decreased expression of GAS1 mRNA CTD PMID:31256213 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
JBrowse link
G Gask1b golgi associated kinase 1B decreases expression ISO hydroquinone results in decreased expression of GASK1B mRNA CTD PMID:31256213 NCBI chr 2:178,678,946...178,751,459
Ensembl chr 2:178,679,041...178,750,668
JBrowse link
G Gata1 GATA binding protein 1 decreases expression
multiple interactions
ISO hydroquinone results in decreased expression of GATA1 mRNA
decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]
CTD PMID:21414390, PMID:23973255 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Gata2 GATA binding protein 2 multiple interactions
decreases expression
ISO hydroquinone promotes the reaction [Hemin results in decreased expression of GATA2 mRNA]
hydroquinone results in decreased expression of GATA2 mRNA
CTD PMID:21414390 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488
JBrowse link
G Gbp2 guanylate binding protein 2 decreases expression ISO hydroquinone results in decreased expression of GBP2 mRNA CTD PMID:31256213 NCBI chr 2:248,276,795...248,293,784
Ensembl chr 2:248,276,709...248,293,784
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO hydroquinone results in increased expression of GCLC mRNA; hydroquinone results in increased expression of GCLC protein CTD PMID:30547568 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO hydroquinone results in increased expression of GCLM mRNA; hydroquinone results in increased expression of GCLM protein CTD PMID:21059386, PMID:30547568, PMID:31256213 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gda guanine deaminase increases expression ISO hydroquinone results in increased expression of GDA mRNA CTD PMID:31256213 NCBI chr 1:238,982,542...239,057,663
Ensembl chr 1:238,982,392...239,057,732
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO hydroquinone results in increased expression of GDF15 mRNA CTD PMID:23416264, PMID:31256213 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO hydroquinone results in increased expression of GDPD3 mRNA CTD PMID:31256213 NCBI chr 1:198,199,032...198,209,178
Ensembl chr 1:198,199,622...198,209,150
JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 increases expression ISO hydroquinone results in increased expression of GFPT1 mRNA CTD PMID:31256213 NCBI chr 4:118,852,046...118,901,583
Ensembl chr 4:118,852,062...118,901,591
JBrowse link
G Gk glycerol kinase increases expression ISO hydroquinone results in increased expression of GK mRNA CTD PMID:31256213 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864
JBrowse link
G Glmp glycosylated lysosomal membrane protein decreases expression ISO hydroquinone results in decreased expression of GLMP mRNA CTD PMID:31256213 NCBI chr 2:187,697,528...187,701,118
Ensembl chr 2:187,697,523...187,701,118
JBrowse link
G Glrx glutaredoxin increases expression ISO hydroquinone results in increased expression of GLRX mRNA CTD PMID:31256213 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944
JBrowse link
G Glul glutamate-ammonia ligase decreases expression ISO hydroquinone results in decreased expression of GLUL mRNA CTD PMID:31256213 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gmpr guanosine monophosphate reductase decreases expression ISO hydroquinone results in decreased expression of GMPR mRNA CTD PMID:31256213 NCBI chr17:19,543,274...19,580,929
Ensembl chr17:19,543,275...19,580,929
JBrowse link
G Gosr2 golgi SNAP receptor complex member 2 decreases expression ISO hydroquinone results in decreased expression of GOSR2 mRNA CTD PMID:31256213 NCBI chr10:91,735,772...91,756,123
Ensembl chr10:91,736,780...91,756,081
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression ISO hydroquinone results in increased expression of GOT1 mRNA CTD PMID:31256213 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO hydroquinone results in increased expression of GPAT3 mRNA CTD PMID:31256213 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Gpr155 G protein-coupled receptor 155 decreases expression ISO hydroquinone results in decreased expression of GPR155 mRNA CTD PMID:31256213 NCBI chr 3:60,051,545...60,105,567
Ensembl chr 3:60,051,535...60,105,242
JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A decreases expression ISO hydroquinone results in decreased expression of GPRC5A mRNA CTD PMID:31256213 NCBI chr 4:168,832,937...168,851,650
Ensembl chr 4:168,832,910...168,851,652
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression ISO hydroquinone results in increased expression of GPX2 mRNA CTD PMID:31256213 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Grb10 growth factor receptor bound protein 10 increases expression ISO hydroquinone results in increased expression of GRB10 mRNA CTD PMID:31256213 NCBI chr14:92,021,851...92,122,249
Ensembl chr14:92,021,851...92,117,923
JBrowse link
G Grb2 growth factor receptor bound protein 2 affects expression ISO hydroquinone affects the expression of GRB2 protein CTD PMID:20021034 NCBI chr10:104,193,953...104,263,071
Ensembl chr10:104,193,955...104,263,071
JBrowse link
G Grhl1 grainyhead-like transcription factor 1 increases expression ISO hydroquinone results in increased expression of GRHL1 mRNA CTD PMID:31256213 NCBI chr 6:43,734,837...43,795,757
Ensembl chr 6:43,743,702...43,794,342
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO hydroquinone results in increased expression of and results in decreased phosphorylation of and results in increased activity of GSK3B protein; IGF1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of GSK3B protein] CTD PMID:28886972 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO hydroquinone inhibits the reaction [Peroxynitrous Acid results in decreased activity of GSR protein] CTD PMID:15831208 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gss glutathione synthetase increases expression
multiple interactions
ISO hydroquinone results in increased expression of GSS protein
NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of GSS protein]
CTD PMID:21059386 NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance ISO GSTM1 gene polymorphism affects the susceptibility to hydroquinone CTD PMID:15141365 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gtpbp2 GTP binding protein 2 increases expression ISO hydroquinone results in increased expression of GTPBP2 mRNA CTD PMID:31256213 NCBI chr 9:17,198,957...17,208,456
Ensembl chr 9:17,198,957...17,209,220
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 increases expression ISO hydroquinone results in increased expression of GUCY1B1 mRNA CTD PMID:31256213 NCBI chr 2:180,976,939...181,026,001
Ensembl chr 2:180,976,939...181,026,024
JBrowse link
G Gvin1 GTPase, very large interferon inducible 1 decreases expression ISO hydroquinone results in decreased expression of GVINP1 mRNA CTD PMID:31256213 NCBI chr 1:173,233,675...173,259,901
Ensembl chr 1:173,252,058...173,259,702
JBrowse link
G H1f4 H1.4 linker histone, cluster member decreases expression ISO hydroquinone results in decreased expression of H1-4 mRNA CTD PMID:23416264 NCBI chr17:43,734,461...43,735,120
Ensembl chr17:43,734,461...43,735,120
JBrowse link
G H1f5 H1.5 linker histone, cluster member decreases expression ISO hydroquinone results in decreased expression of H1-5 mRNA CTD PMID:23416264 NCBI chr17:44,766,313...44,766,981
Ensembl chr17:44,766,313...44,766,981
JBrowse link
G H2ac12 H2A clustered histone 12 decreases expression ISO hydroquinone results in decreased expression of H2AC12 mRNA CTD PMID:23416264 NCBI chr17:44,527,990...44,528,557
Ensembl chr17:44,528,125...44,528,511
JBrowse link
G H2ac20 H2A clustered histone 20 decreases expression ISO hydroquinone results in decreased expression of H2AC20 mRNA CTD PMID:23416264 NCBI chr 2:198,360,271...198,360,735
Ensembl chr 2:198,360,301...198,360,678
JBrowse link
G H2ac21 H2A clustered histone 21 decreases expression ISO hydroquinone results in decreased expression of H2AC21 mRNA CTD PMID:23416264 NCBI chr 2:198,359,754...198,360,146
Ensembl chr 2:198,359,754...198,360,146
JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases phosphorylation
affects localization
increases expression
ISO [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of H2AX protein modified form; [POLH mutant form results in increased susceptibility to hydroquinone] which results in increased expression of H2AX protein; WRN gene mutant form promotes the reaction [hydroquinone results in increased expression of H2AX protein alternative form]; WRN protein affects the reaction [hydroquinone results in increased expression of H2AX protein]
hydroquinone results in increased phosphorylation of H2AX protein
hydroquinone affects the localization of H2AX protein modified form
CTD PMID:17875398, PMID:18835433, PMID:20036648, PMID:21267443, PMID:22981619, PMID:30506647 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G H4f3 H1.3 linker histone, cluster member decreases expression ISO hydroquinone results in decreased expression of H1-3 mRNA CTD PMID:23416264 NCBI chr17:43,797,711...43,798,450
Ensembl chr17:43,797,721...43,798,383
JBrowse link
G Hbb hemoglobin subunit beta multiple interactions ISO decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA] CTD PMID:21414390, PMID:23973255 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO hydroquinone results in increased expression of HBEGF mRNA CTD PMID:31256213 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hdac1 histone deacetylase 1 increases expression ISO hydroquinone results in increased expression of HDAC1 protein CTD PMID:30448557 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 increases expression ISO hydroquinone results in increased expression of HDAC2 protein CTD PMID:30448557 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdac9 histone deacetylase 9 increases expression ISO hydroquinone results in increased expression of HDAC9 mRNA CTD PMID:31256213 NCBI chr 6:53,487,367...54,358,694
Ensembl chr 6:53,488,883...54,059,119
JBrowse link
G Hfe homeostatic iron regulator decreases expression ISO hydroquinone results in decreased expression of HFE mRNA CTD PMID:31256213 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Hist1h4m histone cluster 1, H4m decreases expression ISO hydroquinone results in decreased expression of H4C1 mRNA CTD PMID:23416264 Ensembl chr17:44,815,684...44,815,995 JBrowse link
G Hist2h2aa3 histone cluster 2 H2A family member A3 decreases expression ISO hydroquinone results in decreased expression of H2AC18 mRNA CTD PMID:23416264 NCBI chr 2:198,388,766...198,389,293
Ensembl chr 2:198,388,809...198,389,201
Ensembl chr 2:198,388,809...198,389,201
JBrowse link
G Hist2h4 histone cluster 2, H4 decreases expression ISO hydroquinone results in decreased expression of H4C2 mRNA CTD PMID:23416264 NCBI chr 2:198,411,955...198,412,350
Ensembl chr 2:198,411,955...198,412,350
JBrowse link
G Hjurp Holliday junction recognition protein decreases expression ISO hydroquinone results in decreased expression of HJURP mRNA CTD PMID:23416264 NCBI chr 9:95,347,739...95,362,228
Ensembl chr 9:95,349,086...95,362,014
JBrowse link
G Hmbs hydroxymethylbilane synthase multiple interactions ISO decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA] CTD PMID:21414390, PMID:23973255 NCBI chr 8:48,667,278...48,674,673
Ensembl chr 8:48,667,275...48,674,748
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO hydroquinone results in decreased expression of HMGB2 mRNA CTD PMID:23416264 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO hydroquinone results in increased expression of HMOX1 mRNA
ferric chloride promotes the reaction [hydroquinone results in increased expression of HMOX1 protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]
hydroquinone results in increased expression of HMOX1 mRNA; hydroquinone results in increased expression of HMOX1 protein
CTD PMID:17464197, PMID:21059386, PMID:28645578, PMID:29508652, PMID:30547568, PMID:31256213 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hotairm1 Hoxa transcript antisense RNA, myeloid-specific 1 multiple interactions
affects expression
affects methylation
ISO Decitabine affects the reaction [hydroquinone affects the expression of HOTAIRM1 mRNA]; Decitabine affects the reaction [hydroquinone affects the methylation of HOTAIRM1 promoter]; trichostatin A affects the reaction [hydroquinone affects the expression of HOTAIRM1 mRNA]; trichostatin A affects the reaction [hydroquinone affects the methylation of HOTAIRM1 promoter] CTD PMID:31899212 NCBI chr 4:82,127,355...82,130,853 JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions
affects expression
ISO 3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of HRAS protein]; Doxorubicin inhibits the reaction [hydroquinone results in decreased expression of HRAS protein]; hydroquinone promotes the reaction [PARP1 protein binds to and results in increased ADP-ribosylation of and results in increased expression of HRAS protein]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of HRAS protein]
hydroquinone affects the expression of HRAS mRNA; hydroquinone affects the expression of HRAS protein
CTD PMID:26047893 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 increases expression ISO hydroquinone results in increased expression of HSD17B2 mRNA CTD PMID:31256213 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
G Hspa13 heat shock protein family A (Hsp70) member 13 increases expression ISO hydroquinone results in increased expression of HSPA13 mRNA CTD PMID:31256213 NCBI chr11:14,146,515...14,160,697
Ensembl chr11:14,144,130...14,160,892
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression ISO hydroquinone results in increased expression of HSPA2 mRNA CTD PMID:15452088 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Hyls1 HYLS1, centriolar and ciliogenesis associated decreases expression ISO hydroquinone results in decreased expression of HYLS1 mRNA CTD PMID:23416264 NCBI chr 8:36,763,470...36,772,199
Ensembl chr 8:36,763,481...36,764,422
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO hydroquinone results in increased expression of ID1 mRNA CTD PMID:31256213 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein decreases expression ISO hydroquinone results in decreased expression of ID3 mRNA CTD PMID:31256213 NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
JBrowse link
G Id4 inhibitor of DNA binding 4, HLH protein increases expression ISO hydroquinone results in increased expression of ID4 mRNA CTD PMID:31256213 NCBI chr17:16,692,557...16,695,126
Ensembl chr17:16,692,557...16,695,126
JBrowse link
G Ier3 immediate early response 3 increases expression ISO hydroquinone results in increased expression of IER3 mRNA CTD PMID:31256213 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO hydroquinone results in decreased expression of IFI44 mRNA CTD PMID:31256213 NCBI chr 2:256,897,765...256,915,591
Ensembl chr 2:256,897,772...256,915,569
JBrowse link
G Ifi44l interferon-induced protein 44-like decreases expression ISO hydroquinone results in decreased expression of IFI44L mRNA CTD PMID:31256213 NCBI chr 2:256,948,722...256,979,573
Ensembl chr 2:256,964,860...256,978,668
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 decreases expression ISO hydroquinone results in decreased expression of IFIH1 mRNA CTD PMID:31256213 NCBI chr 3:48,557,696...48,604,097
Ensembl chr 3:48,557,696...48,604,097
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO hydroquinone results in decreased expression of IFIT3 mRNA CTD PMID:31256213 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
JBrowse link
G Ifng interferon gamma multiple interactions ISO hydroquinone inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of CCL2 protein]; hydroquinone inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased expression of IFNG protein]; IFNG protein promotes the reaction [[Lipopolysaccharides co-treated with hydroquinone] results in increased abundance of Nitric Oxide] CTD PMID:3137358, PMID:7884313, PMID:22465845 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO hydroquinone results in increased expression of IFRD1 mRNA CTD PMID:31256213 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO IGF1 protein inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; IGF1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of GSK3B protein]; IGF1 protein inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form] CTD PMID:28886972 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression ISO hydroquinone results in decreased expression of IGFBP3 mRNA CTD PMID:31256213 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] CTD PMID:20054000 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il10 interleukin 10 multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]
hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]
CTD PMID:17464197, PMID:17572062 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12b interleukin 12B multiple interactions
increases expression
ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]
hydroquinone results in increased expression of IL12B mRNA
CTD PMID:15894107, PMID:17464197 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il17a interleukin 17A increases secretion EXP hydroquinone results in increased secretion of IL17A protein CTD PMID:29935983 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
decreases cleavage
ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein]
Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of IL1A protein]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]
hydroquinone results in increased expression of IL1A mRNA; hydroquinone results in increased expression of IL1A protein
hydroquinone results in decreased cleavage of IL1A protein
CTD PMID:1868253, PMID:8548860, PMID:9118901, PMID:28836394, PMID:31256213 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta decreases cleavage
increases expression
decreases secretion
multiple interactions
ISO
EXP
hydroquinone results in decreased cleavage of IL1B protein
hydroquinone results in increased expression of IL1B mRNA
hydroquinone results in decreased secretion of IL1B protein
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
[COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased secretion of IL1B protein; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
CTD PMID:8548860, PMID:9118901, PMID:17464197, PMID:19148301, PMID:22717997, PMID:29908986, PMID:31256213 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1f10 interleukin 1 family member 10 increases expression ISO hydroquinone results in increased expression of IL1F10 mRNA CTD PMID:31256213 NCBI chr 3:1,408,560...1,416,601
Ensembl chr 3:1,413,671...1,416,599
JBrowse link
G Il2 interleukin 2 multiple interactions ISO hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein] CTD PMID:9571986 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL23A mRNA] CTD PMID:17464197 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Il33 interleukin 33 decreases expression ISO hydroquinone results in decreased expression of IL33 mRNA CTD PMID:31256213 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Il36g interleukin 36, gamma increases expression ISO hydroquinone results in increased expression of IL36G mRNA CTD PMID:31256213 NCBI chr 3:1,285,658...1,291,836
Ensembl chr 3:1,285,664...1,291,865
JBrowse link
G Il36rn interleukin 36 receptor antagonist increases expression ISO hydroquinone results in increased expression of IL36RN mRNA CTD PMID:31256213 NCBI chr 3:1,385,256...1,392,275
Ensembl chr 3:1,385,654...1,392,275
JBrowse link
G Il4 interleukin 4 multiple interactions ISO hydroquinone promotes the reaction [keyhole-limpet hemocyanin results in increased expression of IL4 mRNA]; hydroquinone promotes the reaction [keyhole-limpet hemocyanin results in increased expression of IL4 protein] CTD PMID:12153512 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases secretion
EXP
ISO
[COL2A1 protein co-treated with hydroquinone] results in increased expression of IL6 protein; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
hydroquinone results in decreased secretion of IL6 protein
CTD PMID:17464197, PMID:19148301, PMID:20054000, PMID:22302391, PMID:22717997, PMID:29935983 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inhba inhibin subunit beta A increases expression ISO hydroquinone results in increased expression of INHBA mRNA CTD PMID:31256213 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B increases expression ISO hydroquinone results in increased expression of INPP4B mRNA CTD PMID:31256213 NCBI chr19:29,592,889...30,341,528
Ensembl chr19:29,597,905...29,968,424
JBrowse link
G Irs1 insulin receptor substrate 1 decreases expression ISO hydroquinone results in decreased expression of IRS1 mRNA CTD PMID:31256213 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier decreases expression ISO hydroquinone results in decreased expression of ISG15 mRNA CTD PMID:31256213 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Itgb1 integrin subunit beta 1 decreases activity
decreases expression
ISO hydroquinone results in decreased activity of ITGB1 protein
hydroquinone results in decreased expression of ITGB1 mRNA
hydroquinone results in decreased expression of ITGB1 protein
CTD PMID:17464197, PMID:19148301 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Itgb2 integrin subunit beta 2 decreases expression
increases expression
ISO hydroquinone results in decreased expression of ITGB2 protein
hydroquinone results in decreased expression of ITGB2 mRNA
hydroquinone results in increased expression of ITGB2 protein
CTD PMID:17464197, PMID:19148301, PMID:21664406 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Itgb3 integrin subunit beta 3 increases expression ISO hydroquinone results in increased expression of ITGB3 protein CTD PMID:21664406 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Ivl involucrin increases expression ISO hydroquinone results in increased expression of IVL mRNA CTD PMID:31256213 NCBI chr 2:192,761,171...192,773,346
Ensembl chr 2:192,761,538...192,763,577
JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases expression ISO hydroquinone results in decreased expression of JAG1 mRNA CTD PMID:22960397 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Jrk Jrk helix-turn-helix protein decreases expression ISO hydroquinone results in decreased expression of JRK mRNA CTD PMID:31256213 NCBI chr 7:115,941,788...115,946,471
Ensembl chr 7:115,942,743...115,946,425
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit affects localization ISO hydroquinone affects the localization of JUN protein CTD PMID:26807887 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kbtbd6 kelch repeat and BTB domain containing 6 decreases expression ISO hydroquinone results in decreased expression of KBTBD6 mRNA CTD PMID:31256213 NCBI chr15:61,731,574...61,733,331
Ensembl chr15:61,731,735...61,733,742
JBrowse link
G Kbtbd7 kelch repeat and BTB domain containing 7 decreases expression ISO hydroquinone results in decreased expression of KBTBD7 mRNA CTD PMID:31256213 NCBI chr15:61,692,041...61,696,506 JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 decreases expression ISO hydroquinone results in decreased expression of KCNJ15 mRNA CTD PMID:31256213 NCBI chr11:35,545,185...35,588,517
Ensembl chr11:35,568,182...35,585,390
JBrowse link
G Kdm6a lysine demethylase 6A decreases expression ISO hydroquinone results in decreased expression of KDM6A mRNA CTD PMID:31256213 NCBI chr  X:4,805,493...4,945,788
Ensembl chr  X:4,806,277...4,945,944
JBrowse link
G Kif18a kinesin family member 18A decreases expression ISO hydroquinone results in decreased expression of KIF18A mRNA CTD PMID:23416264 NCBI chr 3:100,366,168...100,426,867
Ensembl chr 3:100,366,168...100,427,030
JBrowse link
G Kitlg KIT ligand increases expression ISO hydroquinone results in increased expression of KITLG mRNA CTD PMID:22960397 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Klf2 Kruppel-like factor 2 increases expression ISO hydroquinone results in increased expression of KLF2 mRNA CTD PMID:31256213 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037
JBrowse link
G Klf7 Kruppel like factor 7 increases expression ISO hydroquinone results in increased expression of KLF7 mRNA CTD PMID:31256213 NCBI chr 9:70,740,480...70,787,913
Ensembl chr 9:70,740,480...70,787,913
JBrowse link
G Klhl31 kelch-like family member 31 decreases expression ISO hydroquinone results in decreased expression of KLHL31 mRNA CTD PMID:31256213 NCBI chr 8:84,945,444...84,968,811
Ensembl chr 8:84,945,444...84,968,811
JBrowse link
G Klk6 kallikrein related-peptidase 6 increases expression ISO hydroquinone results in increased expression of KLK6 mRNA CTD PMID:31256213 NCBI chr 1:99,762,195...99,769,486
Ensembl chr 1:99,762,253...99,769,488
JBrowse link
G Klrg2 killer cell lectin like receptor G2 decreases expression ISO hydroquinone results in decreased expression of KLRG2 mRNA CTD PMID:31256213 NCBI chr 4:66,370,674...66,381,351
Ensembl chr 4:66,371,511...66,380,734
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions ISO [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of KRAS protein CTD PMID:28444915 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Krt13 keratin 13 decreases expression ISO hydroquinone results in decreased expression of KRT13 mRNA CTD PMID:31256213 NCBI chr10:88,032,130...88,036,040
Ensembl chr10:88,032,130...88,036,040
JBrowse link
G Krt19 keratin 19 decreases expression ISO hydroquinone results in decreased expression of KRT19 mRNA CTD PMID:31256213 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Krt23 keratin 23 increases expression ISO hydroquinone results in increased expression of KRT23 mRNA CTD PMID:31256213 NCBI chr10:87,391,623...87,407,634
Ensembl chr10:87,391,623...87,407,634
JBrowse link
G Krt24 keratin 24 decreases expression ISO hydroquinone results in decreased expression of KRT24 mRNA CTD PMID:31256213 NCBI chr10:87,190,184...87,195,075
Ensembl chr10:87,189,934...87,195,075
JBrowse link
G Krt78 keratin 78 increases expression ISO hydroquinone results in increased expression of KRT78 mRNA CTD PMID:31256213 NCBI chr 7:143,545,245...143,553,063
Ensembl chr 7:143,545,411...143,552,588
JBrowse link
G Krt80 keratin 80 increases expression ISO hydroquinone results in increased expression of KRT80 mRNA CTD PMID:31256213 NCBI chr 7:142,995,715...143,015,932
Ensembl chr 7:142,994,119...143,016,040
JBrowse link
G Lama4 laminin subunit alpha 4 increases expression
multiple interactions
ISO hydroquinone results in increased expression of LAMA4 protein
[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]
CTD PMID:18055817 NCBI chr20:44,060,715...44,201,966
Ensembl chr20:44,060,731...44,209,614
JBrowse link
G Lasp1 LIM and SH3 protein 1 affects expression ISO hydroquinone affects the expression of LASP1 protein CTD PMID:20021034 NCBI chr10:85,744,662...85,785,130
Ensembl chr10:85,744,568...85,785,133
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO hydroquinone results in increased expression of LCN2 mRNA CTD PMID:31256213 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions
decreases expression
ISO hydroquinone inhibits the reaction [CTNNB1 protein binds to LEF1 protein]
hydroquinone results in decreased expression of LEF1 protein
CTD PMID:28886972 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G Lgalsl galectin-like increases expression ISO hydroquinone results in increased expression of LGALSL mRNA CTD PMID:31256213 NCBI chr14:105,047,915...105,055,421
Ensembl chr14:105,047,919...105,055,421
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 decreases expression ISO hydroquinone results in decreased expression of LGR4 mRNA CTD PMID:31256213 NCBI chr 3:101,051,960...101,152,119
Ensembl chr 3:101,051,955...101,152,119
JBrowse link
G Lipg lipase G, endothelial type increases expression ISO hydroquinone results in increased expression of LIPG mRNA CTD PMID:31256213 NCBI chr18:70,903,528...70,924,434
Ensembl chr18:70,901,710...70,924,708
JBrowse link
G Lmna lamin A/C affects expression ISO hydroquinone affects the expression of LMNA protein CTD PMID:17181942 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G LOC102548682 histone H4-like decreases expression ISO hydroquinone results in decreased expression of H4C6 mRNA CTD PMID:23416264 NCBI chr17:43,616,218...43,673,659
Ensembl chr17:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr 2:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr 2:43,791,657...43,792,067
Ensembl chr 2:43,791,657...43,792,067
JBrowse link
G LOC102550598 small proline-rich protein 2I-like increases expression ISO hydroquinone results in increased expression of SPRR2G mRNA CTD PMID:31256213 NCBI chr 2:192,520,019...192,521,188
Ensembl chr 2:192,520,733...192,520,960
JBrowse link
G LOC102551184 histone H4-like decreases expression ISO hydroquinone results in decreased expression of H4C12 mRNA CTD PMID:23416264 NCBI chr17:43,770,198...43,821,579 JBrowse link
G LOC290595 hypothetical gene supported by AF152002 decreases expression ISO hydroquinone results in decreased expression of C10ORF99 mRNA CTD PMID:31256213 NCBI chr16:14,352,998...14,360,604
Ensembl chr16:14,353,459...14,360,555
JBrowse link
G Loricrin loricrin cornified envelope precursor protein increases expression ISO hydroquinone results in increased expression of LORICRIN mRNA CTD PMID:31256213 NCBI chr 2:191,984,455...191,990,713
Ensembl chr 2:191,984,773...191,986,170
JBrowse link
G Lrrc27 leucine rich repeat containing 27 decreases expression ISO hydroquinone results in decreased expression of LRRC27 mRNA CTD PMID:31256213 NCBI chr 1:211,543,751...211,575,823
Ensembl chr 1:211,543,751...211,575,820
JBrowse link
G Lrriq3 leucine-rich repeats and IQ motif containing 3 decreases expression ISO hydroquinone results in decreased expression of LRRIQ3 mRNA CTD PMID:31256213 NCBI chr 2:261,403,040...261,499,893
Ensembl chr 2:261,402,980...261,499,891
JBrowse link
G Lss lanosterol synthase decreases expression ISO hydroquinone results in decreased expression of LSS mRNA CTD PMID:31256213 NCBI chr20:12,844,522...12,870,474
Ensembl chr20:12,842,884...12,870,497
JBrowse link
G Ly6e lymphocyte antigen 6 family member E decreases expression ISO hydroquinone results in decreased expression of LY6E mRNA CTD PMID:31256213 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Ly96 lymphocyte antigen 96 increases expression ISO hydroquinone results in increased expression of LY96 mRNA CTD PMID:31256213 NCBI chr 5:1,972,212...1,989,448 JBrowse link
G Lypd5 Ly6/Plaur domain containing 5 increases expression ISO hydroquinone results in increased expression of LYPD5 mRNA CTD PMID:31256213 NCBI chr 1:81,202,832...81,213,928
Ensembl chr 1:81,208,212...81,213,937
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO hydroquinone results in increased expression of MAFF mRNA CTD PMID:31256213 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of MAGI1 mRNA; [hydroquinone co-treated with Hemin] affects the expression of MAGI1 protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein] CTD PMID:32198055 NCBI chr 4:125,684,816...126,300,013
Ensembl chr 4:125,687,307...125,958,112
JBrowse link
G Map1b microtubule-associated protein 1B increases expression ISO hydroquinone results in increased expression of MAP1B mRNA CTD PMID:31256213 NCBI chr 2:29,675,391...29,768,750
Ensembl chr 2:29,675,391...29,768,750
JBrowse link
G Map7d2 MAP7 domain containing 2 decreases expression ISO hydroquinone results in decreased expression of MAP7D2 mRNA CTD PMID:31256213 NCBI chr  X:38,400,578...38,467,825
Ensembl chr  X:38,397,261...38,468,360
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK1 protein; hydroquinone results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:15129224 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK3 protein; hydroquinone results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:15129224 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Marchf3 membrane associated ring-CH-type finger 3 increases expression ISO hydroquinone results in increased expression of MARCHF3 mRNA CTD PMID:31256213 NCBI chr18:51,844,980...51,998,017
Ensembl chr18:51,844,976...52,017,734
JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 decreases expression
multiple interactions
increases expression
ISO hydroquinone results in decreased expression of MBD2 mRNA
PARP1 protein affects the reaction [hydroquinone results in increased expression of MBD2 protein]
CTD PMID:22245671, PMID:30448557 NCBI chr18:65,814,026...65,885,115
Ensembl chr18:65,814,026...65,885,114
JBrowse link
G Mbnl3 muscleblind-like splicing regulator 3 decreases expression ISO hydroquinone results in decreased expression of MBNL3 mRNA CTD PMID:31256213 NCBI chr  X:138,378,674...138,473,365
Ensembl chr  X:138,384,912...138,435,391
JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 increases expression ISO hydroquinone results in increased expression of MBOAT2 mRNA CTD PMID:31256213 NCBI chr 6:44,009,872...44,135,501
Ensembl chr 6:44,009,872...44,131,387
JBrowse link
G Mctp1 multiple C2 and transmembrane domain containing 1 increases expression ISO hydroquinone results in increased expression of MCTP1 mRNA CTD PMID:31256213 NCBI chr 2:3,400,883...4,089,949
Ensembl chr 2:3,400,977...4,088,989
JBrowse link
G Mctp2 multiple C2 and transmembrane domain containing 2 decreases expression ISO hydroquinone results in decreased expression of MCTP2 mRNA CTD PMID:31256213 NCBI chr 1:133,324,881...133,559,644
Ensembl chr 1:133,324,301...133,559,975
JBrowse link
G Mettl21a methyltransferase like 21A decreases expression ISO hydroquinone results in decreased expression of METTL21A mRNA CTD PMID:31256213 NCBI chr 9:71,304,138...71,314,015
Ensembl chr 9:71,304,427...71,313,940
JBrowse link
G Mettl7a methyltransferase like 7A decreases expression ISO hydroquinone results in decreased expression of METTL7A mRNA CTD PMID:31256213 NCBI chr 7:141,973,447...142,021,344
Ensembl chr 7:141,973,553...141,981,432
JBrowse link
G MGC105649 hypothetical LOC302884 increases expression ISO hydroquinone results in increased expression of C15ORF48 mRNA CTD PMID:31256213 NCBI chr 3:114,772,603...114,776,156
Ensembl chr 3:114,772,603...114,776,155
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO hydroquinone results in increased expression of MGST1 mRNA CTD PMID:15452088 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Mid1 midline 1 decreases expression ISO hydroquinone results in decreased expression of MID1 mRNA CTD PMID:31256213 NCBI chr  X:25,458,782...25,839,941
Ensembl chr  X:25,458,771...25,628,272
JBrowse link
G Mir155 microRNA 155 multiple interactions
increases expression
ISO Doxorubicin promotes the reaction [hydroquinone results in increased expression of MIR155 mRNA]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MIR155 mRNA]; trichostatin A promotes the reaction [hydroquinone results in increased expression of MIR155 mRNA] CTD PMID:30448557 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir486 microRNA 486 multiple interactions ISO hydroquinone affects the reaction [[Hemin co-treated with MIR486-1 mRNA] affects the expression of RASSF5 mRNA]; hydroquinone inhibits the reaction [Hemin results in increased expression of MIR486-1 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein] CTD PMID:32198055 Ensembl chr16:73,680,363...73,680,490 JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO hydroquinone results in increased expression of MMP1 mRNA CTD PMID:31256213 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions ISO [MMP14 protein co-treated with TIMP2 protein] inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; MMP14 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein] CTD PMID:18055817 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
JBrowse link
G Mmp15 matrix metallopeptidase 15 affects expression ISO hydroquinone affects the expression of MMP15 mRNA CTD PMID:15452088 NCBI chr19:10,079,881...10,101,380
Ensembl chr19:10,079,765...10,101,451
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity
multiple interactions
ISO hydroquinone results in decreased activity of MMP2 protein
[MMP14 protein co-treated with TIMP2 protein] inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; MMP14 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]
CTD PMID:16936130, PMID:18055817 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 affects expression
increases expression
ISO hydroquinone affects the expression of MMP3 mRNA
hydroquinone results in increased expression of MMP3 mRNA
CTD PMID:15452088, PMID:31256213 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
increases secretion
ISO hydroquinone inhibits the reaction [Dicumarol inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]]; hydroquinone promotes the reaction [TNF protein results in increased secretion of MMP9 protein]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased secretion of MMP9 protein]; SB 203580 inhibits the reaction [hydroquinone results in increased secretion of MMP9 protein]
hydroquinone results in increased expression of MMP9 mRNA
CTD PMID:17669387, PMID:26807887 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mob3b MOB kinase activator 3B decreases expression ISO hydroquinone results in decreased expression of MOB3B mRNA CTD PMID:31256213 NCBI chr 5:50,437,444...50,638,136
Ensembl chr 5:50,438,576...50,638,136
JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor multiple interactions
decreases methylation
increases expression
ISO decitabine promotes the reaction [hydroquinone results in increased expression of MPL mRNA]
hydroquinone results in decreased methylation of MPL gene
CTD PMID:22245671 NCBI chr 5:137,268,412...137,282,032
Ensembl chr 5:137,269,480...137,281,298
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases chemical synthesis
increases oxidation
ISO [[[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone] which results in decreased activity of PTPN2 protein; [[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone; [MPO protein co-treated with Hydrogen Peroxide] promotes the reaction [hydroquinone results in decreased activity of TOP2A protein]; [MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone; [MPO protein results in increased hydroxylation of Phenol] which results in increased chemical synthesis of hydroquinone; MPO protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]
MPO protein results in increased chemical synthesis of hydroquinone
MPO protein results in increased oxidation of hydroquinone
CTD PMID:1666626, PMID:10994872, PMID:15777082, PMID:15935818, PMID:31248982 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mpzl3 myelin protein zero-like 3 increases expression ISO hydroquinone results in increased expression of MPZL3 mRNA CTD PMID:31256213 NCBI chr 8:49,354,257...49,374,444
Ensembl chr 8:49,354,115...49,376,687
JBrowse link
G Mt1 metallothionein 1 increases expression ISO hydroquinone results in increased expression of MT1 mRNA CTD PMID:14998373 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 decreases expression ISO hydroquinone results in decreased expression of MTHFD1 mRNA CTD PMID:31256213 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Mtus1 microtubule associated scaffold protein 1 decreases expression ISO hydroquinone results in decreased expression of MTUS1 mRNA CTD PMID:31256213 NCBI chr16:54,240,892...54,386,131
Ensembl chr16:54,291,251...54,386,129
JBrowse link
G Mx2 MX dynamin like GTPase 2 decreases expression ISO hydroquinone results in decreased expression of MX1 mRNA CTD PMID:31256213 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC protein] CTD PMID:12749906 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Mycl MYCL proto-oncogene, bHLH transcription factor decreases expression ISO hydroquinone results in decreased expression of MYCL mRNA CTD PMID:31256213 NCBI chr 5:140,691,947...140,698,837
Ensembl chr 5:140,692,779...140,698,609
JBrowse link
G Mylip myosin regulatory light chain interacting protein decreases expression ISO hydroquinone results in decreased expression of MYLIP mRNA CTD PMID:31256213 NCBI chr17:19,682,040...19,703,681
Ensembl chr17:19,682,040...19,703,681
JBrowse link
G Myo1f myosin IF decreases expression ISO hydroquinone results in decreased expression of MYO1F mRNA CTD PMID:31256213 NCBI chr 7:18,440,742...18,491,448
Ensembl chr 7:18,440,742...18,491,448
JBrowse link
G N4bp2l1 NEDD4 binding protein 2-like 1 decreases expression ISO hydroquinone results in decreased expression of N4BP2L1 mRNA CTD PMID:31256213 NCBI chr12:546,759...576,744
Ensembl chr12:546,760...576,746
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 increases expression ISO hydroquinone results in increased expression of NCF2 mRNA CTD PMID:31256213 NCBI chr13:70,226,441...70,259,019
Ensembl chr13:70,226,647...70,257,576
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase decreases expression ISO hydroquinone results in decreased expression of NEDD4L mRNA CTD PMID:31256213 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720
JBrowse link
G Nefh neurofilament heavy decreases expression ISO hydroquinone results in decreased expression of NEFH mRNA CTD PMID:31256213 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Neu3 neuraminidase 3 increases expression ISO hydroquinone results in increased expression of NEU3 mRNA CTD PMID:23776099 NCBI chr 1:164,803,574...164,814,777
Ensembl chr 1:164,803,574...164,814,651
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 increases expression ISO hydroquinone results in increased expression of NFATC2 mRNA CTD PMID:31256213 NCBI chr 3:165,241,750...165,374,644
Ensembl chr 3:165,245,238...165,360,292
JBrowse link
G Nfe2 nuclear factor, erythroid 2 multiple interactions ISO hydroquinone inhibits the reaction [Hemin results in increased expression of NFE2 mRNA] CTD PMID:21414390 NCBI chr 7:144,872,739...144,880,092
Ensembl chr 7:144,872,747...144,880,092
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
increases expression
increases activity
ISO Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of NFE2L2 promoter]; ferric chloride promotes the reaction [hydroquinone results in increased expression of NFE2L2 protein]; hydroquinone affects the localization of and results in increased degradation of NFE2L2 protein; hydroquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; hydroquinone results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of GSS protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein] CTD PMID:21059386, PMID:21643505, PMID:28645578 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases expression
ISO hydroquinone results in decreased activity of [NFKB1 protein binds to RELA protein]
hydroquinone results in increased expression of NFKB1 protein
CTD PMID:15894107, PMID:30448557 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] CTD PMID:20054000 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbib NFKB inhibitor beta decreases degradation ISO hydroquinone results in decreased degradation of NFKBIB protein CTD PMID:15894107 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845
JBrowse link
G Niban1 niban apoptosis regulator 1 increases expression ISO hydroquinone results in increased expression of NIBAN1 mRNA CTD PMID:31256213 NCBI chr13:68,949,665...69,101,600
Ensembl chr13:68,949,665...69,101,588
JBrowse link
G Nid1 nidogen 1 decreases expression ISO hydroquinone results in decreased expression of NID1 mRNA CTD PMID:31256213 NCBI chr17:90,553,161...90,627,133
Ensembl chr17:90,553,394...90,627,101
JBrowse link
G Nipal3 NIPA-like domain containing 3 decreases expression ISO hydroquinone results in decreased expression of NIPAL3 mRNA CTD PMID:31256213 NCBI chr 5:153,808,169...153,843,961
Ensembl chr 5:153,807,955...153,840,178
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
hydroquinone results in decreased expression of NOS2 mRNA; hydroquinone results in decreased expression of NOS2 protein
CTD PMID:15831208, PMID:17464197, PMID:19148301 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
decreases response to substance
multiple interactions
ISO hydroquinone results in increased expression of NQO1 mRNA; hydroquinone results in increased expression of NQO1 protein
NQO1 protein results in decreased susceptibility to hydroquinone
ferric chloride promotes the reaction [hydroquinone results in increased expression of NQO1 protein]; hydroquinone results in increased expression of and results in increased activity of NQO1 protein; NQO1 protein inhibits the reaction [CNMD protein results in increased susceptibility to hydroquinone]; NQO1 protein inhibits the reaction [hydroquinone results in increased expression of CNMD protein]
CTD PMID:8652659, PMID:10368308, PMID:10393963, PMID:19525446, PMID:21059386, PMID:28645578, PMID:29508652, PMID:30547568, PMID:31256213 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression ISO hydroquinone results in decreased expression of NR4A2 mRNA CTD PMID:31256213 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Nras NRAS proto-oncogene, GTPase decreases expression ISO hydroquinone results in decreased expression of NRAS mRNA CTD PMID:26047893 NCBI chr 2:205,553,119...205,563,716
Ensembl chr 2:205,553,163...205,560,791
JBrowse link
G Nudt16 nudix hydrolase 16 decreases expression ISO hydroquinone results in decreased expression of NUDT16 mRNA CTD PMID:31256213 NCBI chr 8:113,673,069...113,675,124
Ensembl chr 8:113,672,758...113,675,128
JBrowse link
G Nwd2 NACHT and WD repeat domain containing 2 increases expression ISO hydroquinone results in increased expression of NWD2 mRNA CTD PMID:31256213 NCBI chr14:46,136,780...46,153,320
Ensembl chr14:46,136,786...46,153,212
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A decreases expression ISO hydroquinone results in decreased expression of OAS1 mRNA CTD PMID:31256213 NCBI chr12:41,200,680...41,211,393
Ensembl chr12:41,200,718...41,211,909
JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 decreases expression ISO hydroquinone results in decreased expression of OAS2 mRNA CTD PMID:31256213 NCBI chr12:41,341,417...41,363,124
Ensembl chr12:41,340,815...41,363,161
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like increases expression ISO hydroquinone results in increased expression of OASL mRNA CTD PMID:31256213 NCBI chr12:47,444,138...47,456,680
Ensembl chr12:47,444,104...47,456,894
JBrowse link
G Ocln occludin multiple interactions EXP hydroquinone results in decreased degradation of and results in increased expression of OCLN protein CTD PMID:27587462 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Olah oleoyl-ACP hydrolase increases expression ISO hydroquinone results in increased expression of OLAH mRNA CTD PMID:31256213 NCBI chr17:78,878,673...78,903,919
Ensembl chr17:78,879,058...78,903,967
JBrowse link
G Olr1356 olfactory receptor 1356 decreases expression ISO hydroquinone results in decreased expression of OR2C1 mRNA CTD PMID:31256213 NCBI chr10:11,941,947...11,942,885
Ensembl chr10:11,941,947...11,942,885
JBrowse link
G Ovol1 ovo like transcriptional repressor 1 increases expression ISO hydroquinone results in increased expression of OVOL1 mRNA CTD PMID:31256213 NCBI chr 1:220,927,309...220,938,814
Ensembl chr 1:220,925,605...220,938,814
JBrowse link
G P2rx4 purinergic receptor P2X 4 increases expression ISO hydroquinone results in increased expression of P2RX4 mRNA CTD PMID:31256213 NCBI chr12:39,308,022...39,325,673
Ensembl chr12:39,308,025...39,325,673
JBrowse link
G Pa2g4 proliferation-associated 2G4 affects expression ISO hydroquinone affects the expression of PA2G4 protein CTD PMID:17181942 NCBI chr 7:2,979,587...2,987,055
Ensembl chr 7:2,979,588...2,987,055
JBrowse link
G Pabpc4l poly(A) binding protein, cytoplasmic 4-like decreases expression ISO hydroquinone results in decreased expression of PABPC4L mRNA CTD PMID:31256213 NCBI chr 2:130,656,212...130,658,202
Ensembl chr 2:130,656,212...130,658,202
JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase decreases expression ISO hydroquinone results in decreased expression of PAICS mRNA CTD PMID:31256213 NCBI chr14:33,563,884...33,580,944
Ensembl chr14:33,563,886...33,580,566
JBrowse link
G Paip2b poly(A) binding protein interacting protein 2B decreases expression ISO hydroquinone results in decreased expression of PAIP2B mRNA CTD PMID:31256213 NCBI chr 4:115,484,676...115,516,307
Ensembl chr 4:115,487,313...115,516,296
JBrowse link
G Palmd palmdelphin decreases expression ISO hydroquinone results in decreased expression of PALMD mRNA CTD PMID:31256213 NCBI chr 2:220,481,292...220,536,004
Ensembl chr 2:220,481,616...220,535,751
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
affects response to substance
increases expression
increases response to substance
affects expression
multiple interactions
ISO hydroquinone results in increased cleavage of PARP1 protein
PARP1 protein affects the susceptibility to hydroquinone
hydroquinone results in increased expression of PARP1 protein
PARP1 protein results in increased susceptibility to hydroquinone
hydroquinone affects the expression of PARP1 protein
3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of PARP1 protein]; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of and affects the activity of CASP3 protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of BCL2 protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of FAS protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of KRAS protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of TP53 protein; Doxorubicin inhibits the reaction [hydroquinone results in decreased expression of PARP1 protein]; hydroquinone promotes the reaction [PARP1 protein binds to and results in increased ADP-ribosylation of and results in increased expression of HRAS protein]; hydroquinone results in increased expression of and results in increased cleavage of PARP1 protein; Lithium Chloride inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MBD2 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MIR155 mRNA]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of ATG5 mRNA]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of BECN1 mRNA]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of HRAS protein]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]
CTD PMID:19064679, PMID:26047893, PMID:28263894, PMID:28444915, PMID:28886972, PMID:29421518, PMID:30448557 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 decreases expression ISO hydroquinone results in decreased expression of PARP9 mRNA CTD PMID:31256213 NCBI chr11:67,724,071...67,758,027
Ensembl chr11:67,724,076...67,756,799
JBrowse link
G Pbx1 PBX homeobox 1 decreases expression ISO hydroquinone results in decreased expression of PBX1 mRNA CTD PMID:31256213 NCBI chr13:86,390,741...86,671,460
Ensembl chr13:86,390,741...86,451,002
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO hydroquinone results in increased expression of PCK2 mRNA CTD PMID:31256213 NCBI chr15:34,216,735...34,224,357
Ensembl chr15:34,216,833...34,224,193
JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO hydroquinone results in decreased expression of PDCD4 mRNA CTD PMID:31256213 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
JBrowse link
G Pde11a phosphodiesterase 11A decreases expression ISO hydroquinone results in decreased expression of PDE11A mRNA CTD PMID:31256213 NCBI chr 3:62,818,502...63,211,843
Ensembl chr 3:62,818,502...63,211,845
JBrowse link
G Pde4b phosphodiesterase 4B decreases expression ISO hydroquinone results in decreased expression of PDE4B mRNA CTD PMID:31256213 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of PDGFRB mRNA CTD PMID:32198055 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 decreases activity ISO hydroquinone metabolite results in decreased activity of PDPK1 protein; hydroquinone results in decreased activity of PDPK1 protein CTD PMID:20054000 NCBI chr10:13,446,373...13,525,248
Ensembl chr10:13,451,624...13,515,448
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression ISO hydroquinone results in increased expression of PECAM1 protein CTD PMID:21664406 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Peg3 paternally expressed 3 decreases expression ISO hydroquinone results in decreased expression of PEG3 mRNA CTD PMID:31256213 NCBI chr 1:70,210,810...70,237,450
Ensembl chr 1:70,222,964...70,237,443
JBrowse link
G Pgls 6-phosphogluconolactonase affects expression ISO hydroquinone affects the expression of PGLS protein CTD PMID:17181942 NCBI chr16:20,020,444...20,025,930
Ensembl chr16:20,020,444...20,025,930
JBrowse link
G Pglyrp4 peptidoglycan recognition protein 4 increases expression ISO hydroquinone results in increased expression of PGLYRP4 mRNA CTD PMID:31256213 NCBI chr 2:190,125,655...190,204,230
Ensembl chr 2:190,125,693...190,148,265
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression ISO hydroquinone results in increased expression of PHLDA1 mRNA CTD PMID:31256213 NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 decreases expression ISO hydroquinone results in decreased expression of PIK3C3 mRNA CTD PMID:31256213 NCBI chr18:22,964,121...23,047,896
Ensembl chr18:22,964,210...23,047,895
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 decreases expression ISO hydroquinone results in decreased expression of PIK3IP1 mRNA CTD PMID:31256213 NCBI chr14:83,559,397...83,572,481
Ensembl chr14:83,560,541...83,572,473
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased abundance of Reactive Oxygen Species]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein]]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased abundance of Reactive Oxygen Species]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein] CTD PMID:28836394 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression ISO hydroquinone results in increased expression of PIM1 mRNA CTD PMID:31256213 NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555
JBrowse link
G Pitx2 paired-like homeodomain 2 decreases expression ISO hydroquinone results in decreased expression of PITX2 mRNA CTD PMID:31256213 NCBI chr 2:233,602,732...233,621,059
Ensembl chr 2:233,602,732...233,621,129
JBrowse link
G Pkia cAMP-dependent protein kinase inhibitor alpha decreases expression ISO hydroquinone results in decreased expression of PKIA mRNA CTD PMID:31256213 NCBI chr 2:96,593,185...96,668,222
Ensembl chr 2:96,595,088...96,668,222
JBrowse link
G Pkp2 plakophilin 2 increases expression ISO hydroquinone results in increased expression of PKP2 mRNA CTD PMID:31256213 NCBI chr11:88,912,163...88,972,213 JBrowse link
G Plcxd1 phosphatidylinositol-specific phospholipase C, X domain containing 1 increases expression ISO hydroquinone results in increased expression of PLCXD1 mRNA CTD PMID:31256213 NCBI chr12:52,640,939...52,645,153
Ensembl chr12:52,641,222...52,676,608
JBrowse link
G Pld1 phospholipase D1 decreases expression ISO hydroquinone results in decreased expression of PLD1 mRNA CTD PMID:31256213 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403
JBrowse link
G Pllp plasmolipin decreases expression ISO hydroquinone results in decreased expression of PLLP mRNA CTD PMID:31256213 NCBI chr19:10,731,855...10,752,641
Ensembl chr19:10,731,855...10,752,641
JBrowse link
G Pmfbp1 polyamine modulated factor 1 binding protein 1 increases expression ISO hydroquinone results in increased expression of PMFBP1 mRNA CTD PMID:31256213 NCBI chr19:42,132,551...42,196,990
Ensembl chr19:42,132,527...42,180,981
JBrowse link
G Polh DNA polymerase eta increases response to substance
multiple interactions
ISO POLH mutant form results in increased susceptibility to hydroquinone
[POLH mutant form results in increased susceptibility to hydroquinone] which results in increased expression of H2AX protein
CTD PMID:22981619 NCBI chr 9:17,163,354...17,198,006
Ensembl chr 9:17,163,354...17,197,132
JBrowse link
G Polr1b RNA polymerase I subunit B decreases expression ISO hydroquinone results in decreased expression of POLR1B mRNA CTD PMID:31256213 NCBI chr 3:121,632,043...121,656,506
Ensembl chr 3:121,632,043...121,656,506
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO hydroquinone results in increased expression of PPARD mRNA CTD PMID:31256213 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D increases expression ISO hydroquinone results in increased expression of PPM1D mRNA CTD PMID:23416264 NCBI chr10:72,909,550...72,945,884
Ensembl chr10:72,909,550...72,945,884
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO hydroquinone results in increased expression of PPP1R15A mRNA CTD PMID:31256213 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha multiple interactions ISO PPP2CA protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein] CTD PMID:30567741 NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664
JBrowse link
G Ppp2r5a protein phosphatase 2, regulatory subunit B', alpha multiple interactions ISO PPP2R5A protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein] CTD PMID:30567741 NCBI chr13:110,033,550...110,077,946
Ensembl chr13:110,033,550...110,077,946
JBrowse link
G Pptc7 protein phosphatase targeting COQ7 decreases expression ISO hydroquinone results in decreased expression of PPTC7 mRNA CTD PMID:31256213 NCBI chr12:39,731,107...39,769,480
Ensembl chr12:39,731,121...39,769,480
JBrowse link
G Prdm1 PR/SET domain 1 increases expression ISO hydroquinone results in increased expression of PRDM1 mRNA CTD PMID:31256213 NCBI chr20:49,464,921...49,556,623
Ensembl chr20:49,464,919...49,556,518
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO hydroquinone results in increased expression of PRDX1 mRNA CTD PMID:15452088 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit increases expression ISO hydroquinone results in increased expression of PRKDC mRNA; hydroquinone results in increased expression of PRKDC protein CTD PMID:20036648, PMID:23940708 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Prr9 proline rich 9 increases expression ISO hydroquinone results in increased expression of PRR9 mRNA CTD PMID:31256213 NCBI chr 2:192,025,457...192,036,073
Ensembl chr 2:192,025,875...192,027,225
JBrowse link
G Prss3 serine protease 3 increases expression ISO hydroquinone results in increased expression of PRSS3 mRNA CTD PMID:31256213 NCBI chr 4:70,614,524...70,617,998
Ensembl chr 4:70,614,524...70,617,998
JBrowse link
G Psapl1 prosaposin-like 1 increases expression ISO hydroquinone results in increased expression of PSAPL1 mRNA CTD PMID:31256213 NCBI chr14:79,711,694...79,714,254
Ensembl chr14:79,711,694...79,714,254
JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 decreases expression ISO hydroquinone results in decreased expression of PSRC1 mRNA CTD PMID:23416264 NCBI chr 2:211,176,437...211,181,078
Ensembl chr 2:211,176,556...211,181,123
JBrowse link
G Ptgr2 prostaglandin reductase 2 decreases expression ISO hydroquinone results in decreased expression of PTGR2 mRNA CTD PMID:31256213 NCBI chr 6:107,999,832...108,031,645
Ensembl chr 6:107,999,846...108,031,643
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO hydroquinone results in increased expression of PTGS2 mRNA CTD PMID:31256213 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 multiple interactions ISO [[[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone] which results in decreased activity of PTPN2 protein CTD PMID:31248982 NCBI chr18:63,415,298...63,489,240
Ensembl chr18:63,415,306...63,488,027
JBrowse link
G Pygb glycogen phosphorylase B increases expression ISO hydroquinone results in increased expression of PYGB mRNA CTD PMID:31256213 NCBI chr 3:146,581,063...146,629,504
Ensembl chr 3:146,582,752...146,634,535
JBrowse link
G Qpct glutaminyl-peptide cyclotransferase increases expression ISO hydroquinone results in increased expression of QPCT mRNA CTD PMID:31256213 NCBI chr 6:1,657,110...1,689,575
Ensembl chr 6:1,657,331...1,689,559
JBrowse link
G Rab30 RAB30, member RAS oncogene family decreases expression ISO hydroquinone results in decreased expression of RAB30 mRNA CTD PMID:31256213 NCBI chr 1:157,573,344...157,667,973
Ensembl chr 1:157,573,324...157,660,008
JBrowse link
G Rab3b RAB3B, member RAS oncogene family increases expression ISO hydroquinone results in increased expression of RAB3B mRNA CTD PMID:31256213 NCBI chr 5:128,501,789...128,568,170
Ensembl chr 5:128,501,847...128,568,188
JBrowse link
G Rab7b Rab7b, member RAS oncogene family decreases expression ISO hydroquinone results in decreased expression of RAB7B mRNA CTD PMID:31256213 NCBI chr13:48,456,143...48,483,714
Ensembl chr13:48,455,923...48,482,138
JBrowse link
G Rabgap1l RAB GTPase activating protein 1-like decreases expression ISO hydroquinone results in decreased expression of RABGAP1L mRNA CTD PMID:31256213 NCBI chr13:77,975,392...78,609,009
Ensembl chr13:78,011,047...78,609,045
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA; [hydroquinone co-treated with Hemin] affects the expression of RAP1A protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein] CTD PMID:32198055 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA; [hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein] CTD PMID:32198055 NCBI chr 2:177,836,191...178,057,378
Ensembl chr 2:177,836,202...178,057,157
JBrowse link
G Rassf5 Ras association domain family member 5 multiple interactions ISO [hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA; [hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein; hydroquinone affects the reaction [[Hemin co-treated with MIR486-1 mRNA] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein] CTD PMID:32198055 NCBI chr13:47,956,754...48,022,333
Ensembl chr13:47,956,790...48,022,333
JBrowse link
G Rb1 RB transcriptional corepressor 1 increases expression
multiple interactions
ISO hydroquinone results in increased expression of RB protein
[E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein modified form
CTD PMID:26047893, PMID:30506647 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 increases expression ISO hydroquinone results in increased expression of RBCK1 mRNA CTD PMID:31256213 NCBI chr 3:147,793,014...147,809,941
Ensembl chr 3:147,793,017...147,809,919
JBrowse link
G Rdh12 retinol dehydrogenase 12 increases expression ISO hydroquinone results in increased expression of RDH12 mRNA CTD PMID:31256213 NCBI chr 6:102,392,828...102,405,750
Ensembl chr 6:102,392,828...102,405,750
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs decreases expression ISO hydroquinone results in decreased expression of RECK mRNA CTD PMID:31256213 NCBI chr 5:59,348,568...59,415,169
Ensembl chr 5:59,348,639...59,415,135
JBrowse link
G Recql4 RecQ like helicase 4 increases expression ISO hydroquinone results in increased expression of RECQL4 mRNA CTD PMID:15452088 NCBI chr 7:117,765,892...117,773,128
Ensembl chr 7:117,763,783...117,773,134
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of RELA protein]
hydroquinone inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; hydroquinone results in decreased activity of [NFKB1 protein binds to RELA protein]
CTD PMID:15894107, PMID:16928326, PMID:20054000 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Reps1 RALBP1 associated Eps domain containing 1 decreases expression ISO hydroquinone results in decreased expression of REPS1 mRNA CTD PMID:31256213 NCBI chr 1:13,262,049...13,298,347
Ensembl chr 1:13,212,324...13,298,347
JBrowse link
G Rftn1 raftlin lipid raft linker 1 increases expression ISO hydroquinone results in increased expression of RFTN1 mRNA CTD PMID:31256213 NCBI chr 9:12,740,885...12,942,358
Ensembl chr 9:12,740,885...12,942,358
JBrowse link
G Rfx5 regulatory factor X5 decreases expression ISO hydroquinone results in decreased expression of RFX5 mRNA CTD PMID:31256213 NCBI chr 2:196,119,054...196,128,109
Ensembl chr 2:196,120,580...196,128,095
JBrowse link
G RGD1306063 similar to HT021 decreases expression ISO hydroquinone results in decreased expression of C3ORF14 mRNA CTD PMID:31256213 NCBI chr15:12,869,217...12,889,144
Ensembl chr15:12,872,408...12,889,108
JBrowse link
G RGD1309651 similar to 1190005I06Rik protein increases expression ISO hydroquinone results in increased expression of C16ORF74 mRNA CTD PMID:31256213 NCBI chr19:54,184,554...54,210,872
Ensembl chr19:54,184,946...54,210,515
JBrowse link
G RGD1562378 histone H4 variant H4-v.1 decreases expression ISO hydroquinone results in decreased expression of H4C14 mRNA CTD PMID:23416264 NCBI chr 4:170,762,862...170,763,962
Ensembl chr 4:170,763,605...170,763,916
JBrowse link
G RGD1565498 similar to Hypothetical protein LOC270802 decreases expression ISO hydroquinone results in decreased expression of C12ORF66 mRNA CTD PMID:31256213 NCBI chr 7:63,922,871...63,937,721
Ensembl chr 7:63,922,879...63,936,385
JBrowse link
G Rgs17 regulator of G-protein signaling 17 increases expression ISO hydroquinone results in increased expression of RGS17 mRNA CTD PMID:31256213 NCBI chr 1:42,491,566...42,587,735
Ensembl chr 1:42,492,761...42,587,721
JBrowse link
G Rhcg Rh family, C glycoprotein increases expression ISO hydroquinone results in increased expression of RHCG mRNA CTD PMID:31256213 NCBI chr 1:141,325,854...141,349,881
Ensembl chr 1:141,325,856...141,349,881
JBrowse link
G Riok2 RIO kinase 2 decreases expression ISO hydroquinone results in decreased expression of RIOK2 mRNA CTD PMID:31256213 NCBI chr 1:59,130,008...59,146,457
Ensembl chr 1:59,129,951...59,146,776
JBrowse link
G Rnase4 ribonuclease A family member 4 decreases expression ISO hydroquinone results in decreased expression of RNASE4 mRNA CTD PMID:31256213 NCBI chr15:28,018,040...28,035,395
Ensembl chr15:28,018,040...28,035,389
Ensembl chr15:28,018,040...28,035,389
JBrowse link
G Rnasel ribonuclease L decreases expression ISO hydroquinone results in decreased expression of RNASEL mRNA CTD PMID:31256213 NCBI chr13:71,188,712...71,202,636
Ensembl chr13:71,192,142...71,202,625
JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 decreases expression ISO hydroquinone results in decreased expression of ROR1 mRNA CTD PMID:31256213 NCBI chr 5:118,892,874...119,239,528
Ensembl chr 5:119,097,715...119,241,733
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 increases expression ISO hydroquinone results in increased expression of RPS6KA2 mRNA CTD PMID:31256213 NCBI chr 1:53,219,346...53,499,445
Ensembl chr 1:53,360,157...53,499,445
JBrowse link
G Rptn repetin increases expression ISO hydroquinone results in increased expression of RPTN mRNA CTD PMID:31256213 NCBI chr 2:193,722,394...193,729,040
Ensembl chr 2:193,724,248...193,728,302
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO hydroquinone results in increased expression of RRAD mRNA CTD PMID:31256213 NCBI chr19:561,696...564,929
Ensembl chr19:561,727...564,930
JBrowse link
G Rrp12 ribosomal RNA processing 12 homolog decreases expression ISO hydroquinone results in decreased expression of RRP12 mRNA CTD PMID:31256213 NCBI chr 1:261,106,768...261,140,416
Ensembl chr 1:261,106,760...261,140,389
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO hydroquinone results in increased expression of RUNX2 mRNA CTD PMID:22960397 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Satb1 SATB homeobox 1 decreases expression ISO hydroquinone results in decreased expression of SATB1 mRNA CTD PMID:31256213 NCBI chr 9:2,181,135...2,277,949
Ensembl chr 9:2,190,915...2,274,629
JBrowse link
G Sbk1 SH3 domain binding kinase 1 decreases expression ISO hydroquinone results in decreased expression of SBK1 mRNA CTD PMID:31256213 NCBI chr 1:197,636,230...197,681,031
Ensembl chr 1:67,368,384...67,390,141
Ensembl chr 1:67,368,384...67,390,141
JBrowse link
G Scara3 scavenger receptor class A, member 3 decreases expression ISO hydroquinone results in decreased expression of SCARA3 mRNA CTD PMID:31256213 NCBI chr15:42,605,505...42,638,409
Ensembl chr15:42,605,473...42,638,392
JBrowse link
G Scfd2 sec1 family domain containing 2 decreases expression ISO hydroquinone results in decreased expression of SCFD2 mRNA CTD PMID:31256213 NCBI chr14:36,216,002...36,543,661
Ensembl chr14:36,216,002...36,543,658
JBrowse link
G Scg5 secretogranin V increases expression ISO hydroquinone results in increased expression of SCG5 mRNA CTD PMID:31256213 NCBI chr 3:105,235,065...105,279,475
Ensembl chr 3:105,235,050...105,279,462
JBrowse link
G Sdr9c7 short chain dehydrogenase/reductase family 9C, member 7 increases expression ISO hydroquinone results in increased expression of SDR9C7 mRNA CTD PMID:31256213 NCBI chr 7:71,152,366...71,169,510
Ensembl chr 7:71,157,664...71,170,511
JBrowse link
G Sec24d SEC24 homolog D, COPII coat complex component increases expression ISO hydroquinone results in increased expression of SEC24D mRNA CTD PMID:31256213 NCBI chr 2:227,455,704...227,562,801
Ensembl chr 2:227,455,722...227,562,319
JBrowse link
G Selenop selenoprotein P decreases expression ISO hydroquinone results in decreased expression of SELENOP mRNA CTD PMID:31256213 NCBI chr 2:53,105,912...53,116,198
Ensembl chr 2:53,109,684...53,114,858
JBrowse link
G Septin6 septin 6 decreases expression ISO hydroquinone results in decreased expression of SEPTIN6 mRNA CTD PMID:31256213 NCBI chr  X:123,524,954...123,601,214
Ensembl chr  X:123,524,950...123,662,350
JBrowse link
G Serpina12 serpin family A member 12 increases expression ISO hydroquinone results in increased expression of SERPINA12 mRNA CTD PMID:31256213 NCBI chr 6:127,696,501...127,711,238
Ensembl chr 6:127,696,252...127,711,212
JBrowse link
G Serpinb9 serpin family B member 9 increases expression ISO hydroquinone results in increased expression of SERPINB9 mRNA CTD PMID:31256213 NCBI chr17:32,648,846...32,673,047
Ensembl chr17:32,650,441...32,661,865
JBrowse link
G Serpine2 serpin family E member 2 increases expression ISO hydroquinone results in increased expression of SERPINE2 mRNA CTD PMID:31256213 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Sesn1 sestrin 1 increases expression ISO hydroquinone results in increased expression of SESN1 mRNA CTD PMID:23416264 NCBI chr20:46,667,116...46,758,306
Ensembl chr20:46,667,121...46,758,305
JBrowse link
G Sesn2 sestrin 2 increases expression ISO hydroquinone results in increased expression of SESN2 mRNA CTD PMID:23416264, PMID:31256213 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Sesn3 sestrin 3 decreases expression ISO hydroquinone results in decreased expression of SESN3 mRNA CTD PMID:31256213 NCBI chr 8:12,823,060...12,878,749
Ensembl chr 8:12,823,155...12,872,705
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 decreases expression ISO hydroquinone results in decreased expression of SFRP1 mRNA CTD PMID:31256213 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Sfta2 surfactant associated 2 increases expression ISO hydroquinone results in increased expression of SFTA2 mRNA CTD PMID:31256213 NCBI chr20:3,604,918...3,605,643
Ensembl chr20:3,604,904...3,605,638
JBrowse link
G Sgcg sarcoglycan, gamma increases expression ISO hydroquinone results in increased expression of SGCG mRNA CTD PMID:31256213 NCBI chr15:41,549,330...41,595,275
Ensembl chr15:41,549,331...41,595,345
JBrowse link
G Sh3bgr SH3 domain binding glutamate-rich protein increases expression ISO hydroquinone results in increased expression of SH3BGR mRNA CTD PMID:31256213 NCBI chr11:36,555,354...36,579,537
Ensembl chr11:36,555,416...36,579,535
JBrowse link
G Sh3bp2 SH3-domain binding protein 2 increases expression ISO hydroquinone results in increased expression of SH3BP2 mRNA CTD PMID:31256213 NCBI chr14:81,435,445...81,473,013
Ensembl chr14:81,435,449...81,472,952
JBrowse link
G Sh3kbp1 SH3 domain-containing kinase-binding protein 1 increases expression ISO hydroquinone results in increased expression of SH3KBP1 mRNA CTD PMID:31256213 NCBI chr  X:37,790,004...38,196,365
Ensembl chr  X:37,790,586...38,196,204
JBrowse link
G Sh3rf2 SH3 domain containing ring finger 2 decreases expression ISO hydroquinone results in decreased expression of SH3RF2 mRNA CTD PMID:31256213 NCBI chr18:36,371,041...36,471,020
Ensembl chr18:36,371,041...36,471,015
JBrowse link
G Sh3tc1 SH3 domain and tetratricopeptide repeats 1 increases expression ISO hydroquinone results in increased expression of SH3TC1 mRNA CTD PMID:31256213 NCBI chr14:80,184,814...80,229,207
Ensembl chr14:80,195,715...80,229,214
JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 increases expression ISO hydroquinone results in increased expression of SIAH1 mRNA CTD PMID:31256213 NCBI chr19:21,372,163...21,395,773
Ensembl chr19:21,372,163...21,395,767
JBrowse link
G Sik1 salt-inducible kinase 1 decreases expression ISO hydroquinone results in decreased expression of SIK1 mRNA CTD PMID:31256213 NCBI chr20:10,670,747...10,680,279
Ensembl chr20:10,668,411...10,680,283
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of ATG5 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of BECN1 mRNA] CTD PMID:28263894 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc16a6 solute carrier family 16, member 6 decreases expression ISO hydroquinone results in decreased expression of SLC16A6 mRNA CTD PMID:31256213 NCBI chr10:97,733,701...97,758,723
Ensembl chr10:97,735,548...97,756,521
JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression EXP hydroquinone results in increased expression of SLC2A1 protein CTD PMID:27587462 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a12 solute carrier family 2 member 12 decreases expression ISO hydroquinone results in decreased expression of SLC2A12 mRNA CTD PMID:31256213 NCBI chr 1:24,003,625...24,056,373
Ensembl chr 1:24,003,625...24,056,373
JBrowse link
G Slc2a5 solute carrier family 2 member 5 decreases expression ISO hydroquinone results in decreased expression of SLC2A5 mRNA CTD PMID:31256213 NCBI chr 5:167,142,182...167,174,203
Ensembl chr 5:167,141,875...167,174,310
JBrowse link
G Slc5a1 solute carrier family 5 member 1 increases expression ISO hydroquinone results in increased expression of SLC5A1 mRNA CTD PMID:31256213 NCBI chr14:82,910,448...82,975,303
Ensembl chr14:82,909,981...82,975,263
JBrowse link
G Slc5a3 solute carrier family 5 member 3 decreases expression ISO hydroquinone results in decreased expression of SLC5A3 mRNA CTD PMID:31256213 NCBI chr11:32,229,366...32,231,812 JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO hydroquinone results in increased expression of SLC7A11 mRNA CTD PMID:31256213 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Smim5 small integral membrane protein 5 increases expression ISO hydroquinone results in increased expression of SMIM5 mRNA CTD PMID:31256213 NCBI chr10:104,451,222...104,457,002
Ensembl chr10:104,451,222...104,457,001
JBrowse link
G Snx24 sorting nexin 24 increases expression ISO hydroquinone results in increased expression of SNX24 mRNA CTD PMID:31256213 NCBI chr18:48,201,653...48,355,701
Ensembl chr18:48,201,728...48,355,699
JBrowse link
G Sod1 superoxide dismutase 1 decreases activity
decreases expression
ISO hydroquinone results in decreased activity of SOD1 protein
hydroquinone results in decreased expression of SOD1 mRNA
CTD PMID:15816534 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 decreases activity
decreases expression
ISO hydroquinone results in decreased activity of SOD2 protein
hydroquinone results in decreased expression of SOD2 mRNA
CTD PMID:15816534 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sox11 SRY-box transcription factor 11 decreases expression ISO hydroquinone results in decreased expression of SOX11 mRNA CTD PMID:31256213 NCBI chr 6:46,629,967...46,631,988
Ensembl chr 6:46,629,974...46,631,983
JBrowse link
G Sox2 SRY-box transcription factor 2 decreases expression ISO hydroquinone results in decreased expression of SOX2 mRNA CTD PMID:31256213 NCBI chr 2:121,165,137...121,167,545
Ensembl chr 2:121,165,137...121,167,545
JBrowse link
G Sox4 SRY-box transcription factor 4 decreases expression ISO hydroquinone results in decreased expression of SOX4 mRNA CTD PMID:31256213 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Sp110 SP110 nuclear body protein decreases expression ISO hydroquinone results in decreased expression of SP110 mRNA CTD PMID:31256213 NCBI chr 9:92,593,909...92,618,867
Ensembl chr 9:92,593,910...92,616,165
JBrowse link
G Spi1 Spi-1 proto-oncogene increases phosphorylation ISO hydroquinone results in increased phosphorylation of SPI1 protein CTD PMID:16642264 NCBI chr 3:79,918,127...79,937,708
Ensembl chr 3:79,918,969...79,938,301
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 increases expression ISO hydroquinone results in increased expression of SPINK1 mRNA CTD PMID:31256213 NCBI chr18:38,221,919...38,242,092
Ensembl chr18:38,221,681...38,242,119
JBrowse link
G Spink4 serine peptidase inhibitor, Kazal type 4 decreases expression ISO hydroquinone results in decreased expression of SPINK4 mRNA CTD PMID:31256213 NCBI chr 5:57,238,221...57,252,654
Ensembl chr 5:57,239,086...57,250,662
JBrowse link
G Spink6 serine peptidase inhibitor, Kazal type 6 decreases expression ISO hydroquinone results in decreased expression of SPINK6 mRNA CTD PMID:31256213 NCBI chr  X:43,033,066...43,044,975
Ensembl chr  X:43,033,066...43,044,975
JBrowse link
G Sprr3 small proline-rich protein 3 increases expression ISO hydroquinone results in increased expression of SPRR3 mRNA CTD PMID:31256213 NCBI chr 2:192,641,472...192,643,942
Ensembl chr 2:192,641,790...192,642,548
JBrowse link
G Spry4 sprouty RTK signaling antagonist 4 increases expression ISO hydroquinone results in increased expression of SPRY4 mRNA CTD PMID:31256213 NCBI chr18:32,593,370...32,609,890
Ensembl chr18:32,594,958...32,609,864
JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO hydroquinone results in decreased expression of SQSTM1 protein CTD PMID:28263894 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 decreases expression ISO hydroquinone results in decreased expression of ST3GAL3 mRNA CTD PMID:23776099 NCBI chr 5:136,765,309...136,965,642
Ensembl chr 5:136,766,208...136,965,191
JBrowse link
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 decreases expression ISO hydroquinone results in decreased expression of ST6GALNAC5 mRNA CTD PMID:31256213 NCBI chr 2:258,025,177...259,150,709
Ensembl chr 2:258,025,177...258,052,835
JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression ISO hydroquinone results in decreased expression of STAT1 mRNA CTD PMID:31256213 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stc2 stanniocalcin 2 increases expression ISO hydroquinone results in increased expression of STC2 mRNA CTD PMID:23416264, PMID:31256213 NCBI chr10:16,542,909...16,552,675
Ensembl chr10:16,542,882...16,553,295
JBrowse link
G Stk40 serine/threonine kinase 40 increases expression ISO hydroquinone results in increased expression of STK40 mRNA CTD PMID:31256213 NCBI chr 5:144,112,612...144,150,653
Ensembl chr 5:144,114,012...144,150,647
JBrowse link
G Stxbp6 syntaxin binding protein 6 decreases expression ISO hydroquinone results in decreased expression of STXBP6 mRNA CTD PMID:31256213 NCBI chr 6:65,086,483...65,319,527
Ensembl chr 6:65,089,318...65,319,527
JBrowse link
G Sybu syntabulin increases expression ISO hydroquinone results in increased expression of SYBU mRNA CTD PMID:31256213 NCBI chr 7:83,600,614...83,670,121
Ensembl chr 7:83,600,617...83,670,356
JBrowse link
G Sycp2l synaptonemal complex protein 2-like decreases expression ISO hydroquinone results in decreased expression of SYCP2L mRNA CTD PMID:31256213 NCBI chr17:21,430,470...21,486,091 JBrowse link
G Taf3 TATA-box binding protein associated factor 3 decreases expression ISO hydroquinone results in decreased expression of TAF3 mRNA CTD PMID:31256213 NCBI chr17:72,240,785...72,393,448
Ensembl chr17:72,209,373...72,394,271
JBrowse link
G Taldo1 transaldolase 1 affects expression ISO hydroquinone affects the expression of TALDO1 protein CTD PMID:20021034 NCBI chr 1:214,375,555...214,385,886
Ensembl chr 1:214,375,515...214,385,885
JBrowse link
G Tardbp TAR DNA binding protein affects expression ISO hydroquinone affects the expression of TARDBP protein CTD PMID:20021034 NCBI chr 5:165,432,089...165,442,232
Ensembl chr 5:165,432,095...165,442,048
JBrowse link
G Tceanc transcription elongation factor A N-terminal and central domain containing decreases expression ISO hydroquinone results in decreased expression of TCEANC mRNA CTD PMID:31256213 NCBI chr  X:29,498,762...29,505,494
Ensembl chr  X:29,504,349...29,505,425
JBrowse link
G Tcf4 transcription factor 4 decreases expression ISO hydroquinone results in decreased expression of TCF4 mRNA CTD PMID:31256213 NCBI chr18:65,285,320...65,507,983
Ensembl chr18:65,155,685...65,507,977
JBrowse link
G Tenm4 teneurin transmembrane protein 4 decreases expression ISO hydroquinone results in decreased expression of TENM4 mRNA CTD PMID:31256213 NCBI chr 1:161,183,858...161,885,094
Ensembl chr 1:161,401,527...161,880,923
JBrowse link
G Tfrc transferrin receptor multiple interactions
decreases expression
ISO hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFRC protein]; hydroquinone promotes the reaction [Hemin results in decreased expression of TFRC mRNA]
hydroquinone results in decreased expression of TFRC protein
CTD PMID:12749906, PMID:21414390 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 decreases expression ISO hydroquinone results in decreased expression of TGFBR3 mRNA CTD PMID:31256213 NCBI chr14:3,506,416...3,680,508
Ensembl chr14:3,506,339...3,682,545
JBrowse link
G Thnsl1 threonine synthase-like 1 decreases expression ISO hydroquinone results in decreased expression of THNSL1 mRNA CTD PMID:31256213 NCBI chr17:88,095,830...88,102,264
Ensembl chr17:88,095,830...88,102,262
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions ISO [MMP14 protein co-treated with TIMP2 protein] inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein] CTD PMID:18055817 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression ISO hydroquinone results in increased expression of TIPARP mRNA CTD PMID:23416264 NCBI chr 2:157,316,293...157,342,979
Ensembl chr 2:157,316,266...157,341,469
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP hydroquinone results in decreased degradation of and results in increased expression of TJP1 protein CTD PMID:27587462 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tk2 thymidine kinase 2 decreases expression ISO hydroquinone results in decreased expression of TK2 mRNA CTD PMID:31256213 NCBI chr19:917,203...939,236
Ensembl chr19:917,203...939,221
JBrowse link
G Tkt transketolase increases expression ISO hydroquinone results in increased expression of TKT mRNA CTD PMID:31256213 NCBI chr16:6,609,670...6,634,608
Ensembl chr16:6,609,668...6,634,595
JBrowse link
G Tlr3 toll-like receptor 3 decreases expression ISO hydroquinone results in decreased expression of TLR3 mRNA CTD PMID:31256213 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] CTD PMID:20054000 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tmc6 transmembrane channel like 6 decreases expression ISO hydroquinone results in decreased expression of TMC6 mRNA CTD PMID:31256213 NCBI chr10:106,766,857...106,783,004 JBrowse link
G Tmem106a transmembrane protein 106A decreases expression ISO hydroquinone results in decreased expression of TMEM106A mRNA CTD PMID:31256213 NCBI chr10:89,484,269...89,493,288
Ensembl chr10:89,484,468...89,493,283
JBrowse link
G Tmem125 transmembrane protein 125 increases expression ISO hydroquinone results in increased expression of TMEM125 mRNA CTD PMID:31256213 NCBI chr 5:137,371,825...137,373,229
Ensembl chr 5:137,371,825...137,373,205
Ensembl chr 5:137,371,825...137,373,205
JBrowse link
G Tmem19 transmembrane protein 19 decreases expression ISO hydroquinone results in decreased expression of TMEM19 mRNA CTD PMID:31256213 NCBI chr 7:58,316,583...58,343,761
Ensembl chr 7:58,316,514...58,343,145
JBrowse link
G Tmem200a transmembrane protein 200A increases expression ISO hydroquinone results in increased expression of TMEM200A mRNA CTD PMID:31256213 NCBI chr 1:20,330,670...20,413,921
Ensembl chr 1:20,331,976...20,412,381
JBrowse link
G Tmem45b transmembrane protein 45b increases expression ISO hydroquinone results in increased expression of TMEM45B mRNA CTD PMID:31256213 NCBI chr 8:32,563,872...32,609,212
Ensembl chr 8:32,563,874...32,609,212
JBrowse link
G Tmem97 transmembrane protein 97 decreases expression ISO hydroquinone results in decreased expression of TMEM97 mRNA CTD PMID:31256213 NCBI chr10:65,811,455...65,820,538
Ensembl chr10:65,811,456...65,820,538
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
decreases activity
increases secretion
ISO
EXP
Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of TNF protein]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein]]; hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; hydroquinone inhibits the reaction [Dicumarol inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]]; hydroquinone promotes the reaction [TNF protein results in increased secretion of MMP9 protein]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein]
hydroquinone results in decreased activity of TNF protein
[COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased expression of and results in increased secretion of TNF protein; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
hydroquinone results in increased secretion of TNF protein
[hydroquinone results in increased expression of TNF protein] which results in increased susceptibility to Methacholine Chloride; Chlorpromazine inhibits the reaction [[hydroquinone results in increased expression of TNF protein] which results in increased susceptibility to Methacholine Chloride]; Chlorpromazine inhibits the reaction [hydroquinone results in increased expression of TNF protein]; Cromolyn Sodium inhibits the reaction [[hydroquinone results in increased expression of TNF protein] which results in increased susceptibility to Methacholine Chloride]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; hydroquinone metabolite inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF protein]
CTD PMID:9571986, PMID:10890505, PMID:17118622, PMID:17464197, PMID:17669387, PMID:19148301, PMID:20054000, PMID:22414385, PMID:22717997, PMID:28836394, PMID:29908986 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 increases expression ISO hydroquinone results in increased expression of TNFAIP2 mRNA CTD PMID:31256213 NCBI chr 6:135,890,869...135,903,647
Ensembl chr 6:135,890,931...135,903,647
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A increases expression ISO hydroquinone results in increased expression of TNFRSF12A mRNA CTD PMID:31256213 NCBI chr10:12,995,904...12,997,930
Ensembl chr10:12,995,904...12,997,930
JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 decreases expression ISO hydroquinone results in decreased expression of TNFRSF25 mRNA CTD PMID:15452088 NCBI chr 5:169,288,419...169,293,137
Ensembl chr 5:169,288,871...169,293,137
JBrowse link
G Tnfrsf26 tumor necrosis factor receptor superfamily, member 26 decreases expression ISO hydroquinone results in decreased expression of TNFRSF10D mRNA CTD PMID:23416264 NCBI chr 1:216,808,642...216,829,361
Ensembl chr 1:216,808,632...216,828,651
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO hydroquinone results in increased expression of TNFRSF9 mRNA CTD PMID:22723965 NCBI chr 5:168,009,245...168,035,813
Ensembl chr 5:168,009,393...168,035,810
JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression ISO hydroquinone results in decreased expression of TNFSF11 mRNA CTD PMID:31256213 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Tnfsf12 TNF superfamily member 12 decreases expression ISO hydroquinone results in decreased expression of TNFSF12 mRNA CTD PMID:15452088 NCBI chr10:56,290,780...56,300,137
Ensembl chr10:56,290,780...56,300,077
JBrowse link
G Tnik TRAF2 and NCK interacting kinase increases expression ISO hydroquinone results in increased expression of TNIK mRNA CTD PMID:31256213 NCBI chr 2:113,984,599...114,391,805
Ensembl chr 2:113,984,646...114,384,894
JBrowse link
G Top2a DNA topoisomerase II alpha affects activity
decreases activity
multiple interactions
ISO hydroquinone affects the activity of TOP2A protein
hydroquinone results in decreased activity of TOP2A protein
[MPO protein co-treated with Hydrogen Peroxide] promotes the reaction [hydroquinone results in decreased activity of TOP2A protein]
CTD PMID:9118903, PMID:11468185, PMID:15211611, PMID:15833037, PMID:15935818, PMID:20034485 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Tp53 tumor protein p53 increases expression
decreases expression
multiple interactions
ISO hydroquinone results in increased expression of TP53 protein
hydroquinone results in decreased expression of TP53 mRNA
[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of TP53 protein; WRN protein affects the reaction [hydroquinone results in increased acetylation of TP53 protein]; WRN protein affects the reaction [hydroquinone results in increased expression of TP53 protein]
CTD PMID:17875398, PMID:26047893, PMID:28444915 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO hydroquinone results in increased expression of TP53INP1 mRNA CTD PMID:23416264 NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888
JBrowse link
G Tprg1 tumor protein p63 regulated 1 increases expression ISO hydroquinone results in increased expression of TPRG1 mRNA CTD PMID:31256213 NCBI chr11:78,733,046...78,861,745
Ensembl chr11:78,728,128...78,861,716
JBrowse link
G Tradd TNFRSF1A-associated via death domain increases expression ISO hydroquinone results in increased expression of TRADD mRNA CTD PMID:15452088 NCBI chr19:37,214,461...37,221,099
Ensembl chr19:37,214,471...37,216,572
JBrowse link
G Traf4 Tnf receptor associated factor 4 decreases expression ISO hydroquinone results in decreased expression of TRAF4 mRNA CTD PMID:15452088 NCBI chr10:65,418,688...65,424,802
Ensembl chr10:65,418,700...65,424,802
JBrowse link
G Trib1 tribbles pseudokinase 1 increases expression ISO hydroquinone results in increased expression of TRIB1 mRNA CTD PMID:31256213 NCBI chr 7:99,954,492...99,961,026
Ensembl chr 7:99,954,492...99,961,026
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO hydroquinone results in increased expression of TRIB3 mRNA CTD PMID:31256213 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Trim59 tripartite motif-containing 59 decreases expression ISO hydroquinone results in decreased expression of TRIM59 mRNA CTD PMID:23416264 NCBI chr 2:165,629,903...165,641,751
Ensembl chr 2:165,629,918...165,641,573
JBrowse link
G Trim62 tripartite motif-containing 62 increases expression ISO hydroquinone results in increased expression of TRIM62 mRNA CTD PMID:31256213 NCBI chr 5:147,068,725...147,099,024
Ensembl chr 5:147,069,616...147,095,242
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO hydroquinone results in increased activity of TRPA1 protein CTD PMID:21591660 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link
G Tshz1 teashirt zinc finger homeobox 1 decreases expression ISO hydroquinone results in decreased expression of TSHZ1 mRNA CTD PMID:31256213 NCBI chr18:80,860,995...80,907,744
Ensembl chr18:80,862,372...80,865,584
JBrowse link
G Tslp thymic stromal lymphopoietin increases expression ISO hydroquinone results in increased expression of TSLP mRNA CTD PMID:31256213 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
G Ttc14 tetratricopeptide repeat domain 14 decreases expression ISO hydroquinone results in decreased expression of TTC14 mRNA CTD PMID:31256213 NCBI chr 2:120,266,883...120,277,505
Ensembl chr 2:120,266,933...120,276,616
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO hydroquinone results in increased expression of TXN mRNA CTD PMID:15452088 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO hydroquinone results in increased expression of TXNRD1 mRNA CTD PMID:15452088, PMID:31256213 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase increases expression ISO hydroquinone results in increased expression of UGCG mRNA CTD PMID:31256213 NCBI chr 5:76,376,722...76,419,564
Ensembl chr 5:76,386,836...76,419,560
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases metabolic processing EXP UGT1A6 protein results in increased metabolism of hydroquinone CTD PMID:9118891 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 decreases expression ISO hydroquinone results in decreased expression of UHRF1 protein CTD PMID:27979589 NCBI chr 9:10,738,211...10,758,403
Ensembl chr 9:10,738,222...10,757,954
JBrowse link
G Unc5b unc-5 netrin receptor B increases expression ISO hydroquinone results in increased expression of UNC5B mRNA CTD PMID:31256213 NCBI chr20:30,339,680...30,406,593
Ensembl chr20:30,339,673...30,406,295
JBrowse link
G Upp1 uridine phosphorylase 1 increases expression ISO hydroquinone results in increased expression of UPP1 mRNA CTD PMID:31256213 NCBI chr14:89,314,234...89,334,060
Ensembl chr14:89,314,176...89,334,276
JBrowse link
G Usp51 ubiquitin specific peptidase 51 decreases expression ISO hydroquinone results in decreased expression of USP51 mRNA CTD PMID:31256213 NCBI chr  X:19,268,352...19,273,753
Ensembl chr  X:19,270,181...19,273,139
JBrowse link
G Vapa VAMP associated protein A decreases expression ISO hydroquinone results in decreased expression of VAPA mRNA CTD PMID:31256213 NCBI chr 9:113,300,831...113,331,872
Ensembl chr 9:113,300,832...113,331,319
JBrowse link
G Vasn vasorin increases expression ISO hydroquinone results in increased expression of VASN mRNA CTD PMID:31256213 NCBI chr10:11,121,041...11,131,548
Ensembl chr10:11,121,041...11,131,548
JBrowse link
G Vldlr very low density lipoprotein receptor increases expression ISO hydroquinone results in increased expression of VLDLR mRNA CTD PMID:31256213 NCBI chr 1:245,236,819...245,273,688
Ensembl chr 1:245,237,736...245,269,205
JBrowse link
G Vsig10l V-set and immunoglobulin domain containing 10 like increases expression ISO hydroquinone results in increased expression of VSIG10L mRNA CTD PMID:31256213 NCBI chr 1:98,458,691...98,467,444
Ensembl chr 1:98,459,834...98,467,262
JBrowse link
G Vsnl1 visinin-like 1 decreases expression ISO hydroquinone results in decreased expression of VSNL1 mRNA CTD PMID:31256213 NCBI chr 6:37,001,360...37,121,969
Ensembl chr 6:37,001,356...37,122,023
JBrowse link
G Vwde von Willebrand factor D and EGF domains decreases expression ISO hydroquinone results in decreased expression of VWDE mRNA CTD PMID:31256213 NCBI chr 4:39,632,555...39,711,430
Ensembl chr 4:39,665,015...39,711,271
JBrowse link
G Wfdc12 WAP four-disulfide core domain 12 increases expression ISO hydroquinone results in increased expression of WFDC12 mRNA CTD PMID:31256213 NCBI chr 3:160,581,449...160,581,798
Ensembl chr 3:160,581,449...160,581,798
JBrowse link
G Wnt4 Wnt family member 4 decreases expression ISO hydroquinone results in decreased expression of WNT4 mRNA CTD PMID:31256213 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
G Wnt5a Wnt family member 5A increases expression ISO hydroquinone results in increased expression of WNT5A mRNA CTD PMID:22960397 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
G Wrn WRN RecQ like helicase multiple interactions
decreases response to substance
increases response to substance
ISO WRN gene mutant form promotes the reaction [hydroquinone results in increased expression of H2AX protein alternative form]; WRN protein affects the reaction [hydroquinone results in increased acetylation of TP53 protein]; WRN protein affects the reaction [hydroquinone results in increased expression of H2AX protein]; WRN protein affects the reaction [hydroquinone results in increased expression of TP53 protein]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of CASP7 protein]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]
WRN protein results in decreased susceptibility to hydroquinone
WRN gene mutant form results in increased susceptibility to hydroquinone
CTD PMID:17875398, PMID:18978339, PMID:19064679, PMID:21267443 NCBI chr16:62,483,773...62,619,018
Ensembl chr16:62,483,761...62,615,375
JBrowse link
G Xaf1 XIAP associated factor 1 decreases expression ISO hydroquinone results in decreased expression of XAF1 mRNA CTD PMID:31256213 NCBI chr10:58,860,647...58,872,782
Ensembl chr10:58,860,940...58,873,674
JBrowse link
G Xkrx XK related, X-linked increases expression ISO hydroquinone results in increased expression of XKRX mRNA CTD PMID:31256213 NCBI chr  X:104,973,083...104,984,261
Ensembl chr  X:104,968,582...104,984,341
JBrowse link
G Xpnpep3 X-prolyl aminopeptidase 3 decreases expression ISO hydroquinone results in decreased expression of XPNPEP3 mRNA CTD PMID:31256213 NCBI chr 7:122,636,252...122,686,983
Ensembl chr 7:122,636,171...122,688,819
JBrowse link
G Zfp2 zinc finger protein 2 decreases expression ISO hydroquinone results in decreased expression of ZFP2 mRNA CTD PMID:31256213 NCBI chr10:36,388,136...36,406,721
Ensembl chr10:36,388,137...36,402,619
JBrowse link
hydroquinone O-beta-D-glucopyranoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca13 ATP binding cassette subfamily A member 13 decreases expression ISO Arbutin results in decreased expression of ABCA13 mRNA CTD PMID:17103032 NCBI chr14:89,384,512...89,876,748
Ensembl chr14:89,384,512...89,714,917
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase decreases expression ISO Arbutin results in decreased expression of ACMSD mRNA CTD PMID:17103032 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link
G Acvrl1 activin A receptor like type 1 decreases expression ISO Arbutin results in decreased expression of ACVRL1 mRNA CTD PMID:17103032 NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335
JBrowse link
G Adam19 ADAM metallopeptidase domain 19 decreases expression ISO Arbutin results in decreased expression of ADAM19 mRNA CTD PMID:17103032 NCBI chr10:31,146,107...31,240,582
Ensembl chr10:31,146,107...31,240,582
JBrowse link
G Adam20 ADAM metallopeptidase domain 20 decreases expression ISO Arbutin results in decreased expression of ADAM20 mRNA CTD PMID:17103032
G Adam7 ADAM metallopeptidase domain 7 increases expression ISO Arbutin results in increased expression of ADAM7 mRNA CTD PMID:17103032 NCBI chr15:49,418,946...49,467,174
Ensembl chr15:49,418,946...49,467,174
JBrowse link
G Adamts3 ADAM metallopeptidase with thrombospondin type 1, motif 3 decreases expression ISO Arbutin results in decreased expression of ADAMTS3 mRNA CTD PMID:17103032 NCBI chr14:19,866,278...20,072,896
Ensembl chr14:19,866,408...20,070,994
JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 decreases expression ISO Arbutin results in decreased expression of ADAMTS9 mRNA CTD PMID:17103032 NCBI chr 4:124,660,254...124,860,997
Ensembl chr 4:124,660,262...124,858,250
JBrowse link
G Adrb3 adrenoceptor beta 3 decreases expression ISO Arbutin results in decreased expression of ADRB3 mRNA CTD PMID:17103032 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
JBrowse link
G Aebp2 AE binding protein 2 increases expression ISO Arbutin results in increased expression of AEBP2 mRNA CTD PMID:17103032 NCBI chr 4:174,799,378...174,863,260
Ensembl chr 4:174,810,959...174,863,260
JBrowse link
G Afap1 actin filament associated protein 1 decreases expression ISO Arbutin results in decreased expression of AFAP1 mRNA CTD PMID:17103032 NCBI chr14:79,923,132...80,035,096
Ensembl chr14:79,919,717...79,988,110
JBrowse link
G Agbl4 ATP/GTP binding protein-like 4 decreases expression ISO Arbutin results in decreased expression of AGBL4 mRNA CTD PMID:17103032 NCBI chr 5:130,742,297...131,656,581
NCBI chr 5:130,286,393...130,305,884
Ensembl chr 5:131,380,297...131,455,211
Ensembl chr 5:131,380,297...131,455,211
JBrowse link
G Agpat3 1-acylglycerol-3-phosphate O-acyltransferase 3 decreases expression ISO Arbutin results in decreased expression of AGPAT3 mRNA CTD PMID:17103032 NCBI chr20:11,060,584...11,144,806
Ensembl chr20:11,114,164...11,144,806
JBrowse link
G Ahnak AHNAK nucleoprotein decreases expression ISO Arbutin results in decreased expression of AHNAK mRNA CTD PMID:17103032 NCBI chr 1:225,184,883...225,429,638
Ensembl chr 1:225,184,939...225,215,015
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression ISO Arbutin results in decreased expression of AKT1 mRNA CTD PMID:17103032 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin multiple interactions ISO ALB protein binds to and affects the transport of Arbutin CTD PMID:8831264 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Amtn amelotin decreases expression ISO Arbutin results in decreased expression of AMTN mRNA CTD PMID:17103032 NCBI chr14:21,282,488...21,301,966
Ensembl chr14:21,286,510...21,299,068
JBrowse link
G Ankrd17 ankyrin repeat domain 17 increases expression ISO Arbutin results in increased expression of ANKRD17 mRNA CTD PMID:17103032 NCBI chr14:19,291,025...19,431,521
Ensembl chr14:19,318,565...19,431,515
JBrowse link
G Ankrd23 ankyrin repeat domain 23 increases expression ISO Arbutin results in increased expression of ANKRD23 mRNA CTD PMID:17103032 NCBI chr 9:43,110,980...43,117,585
Ensembl chr 9:43,112,141...43,116,521
JBrowse link
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 decreases expression ISO Arbutin results in decreased expression of AP1S1 mRNA CTD PMID:17103032 NCBI chr12:22,665,128...22,676,079
Ensembl chr12:22,665,112...22,676,075
JBrowse link
G Apom apolipoprotein M increases expression ISO Arbutin results in increased expression of APOM mRNA CTD PMID:17103032 NCBI chr20:5,120,473...5,123,073
Ensembl chr20:5,120,474...5,123,073
JBrowse link
G Aptx aprataxin decreases expression ISO Arbutin results in decreased expression of APTX mRNA CTD PMID:17103032 NCBI chr 5:56,987,714...57,009,481
Ensembl chr 5:56,987,909...57,008,859
JBrowse link
G Arfip2 ADP-ribosylation factor interacting protein 2 decreases expression ISO Arbutin results in decreased expression of ARFIP2 mRNA CTD PMID:17103032 NCBI chr 1:170,464,995...170,471,138
Ensembl chr 1:170,466,395...170,471,076
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 decreases expression ISO Arbutin results in decreased expression of ARHGEF2 mRNA CTD PMID:17103032 NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377
JBrowse link
G Arl2 ADP-ribosylation factor like GTPase 2 decreases expression ISO Arbutin results in decreased expression of ARL2 mRNA CTD PMID:17103032 NCBI chr 1:221,504,150...221,516,191
Ensembl chr 1:221,504,170...221,516,110
JBrowse link
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 increases expression ISO Arbutin results in increased expression of ARL6IP1 mRNA CTD PMID:17103032 NCBI chr 1:187,770,160...187,779,675
Ensembl chr 1:187,770,160...187,779,675
JBrowse link
G Arx aristaless related homeobox decreases expression ISO Arbutin results in decreased expression of ARX mRNA CTD PMID:17103032 NCBI chr  X:62,363,757...62,376,139
Ensembl chr  X:62,363,757...62,376,143
JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 increases expression ISO Arbutin results in increased expression of ASAP1 mRNA CTD PMID:17103032 NCBI chr 7:104,670,076...104,951,090
Ensembl chr 7:104,669,672...104,801,045
JBrowse link
G Asap3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 decreases expression ISO Arbutin results in decreased expression of ASAP3 mRNA CTD PMID:17103032 NCBI chr 5:154,551,901...154,596,125
Ensembl chr 5:154,552,195...154,594,785
JBrowse link
G Atf6b activating transcription factor 6 beta decreases expression ISO Arbutin results in decreased expression of ATF6B mRNA CTD PMID:17103032 NCBI chr20:4,414,283...4,422,283
Ensembl chr20:4,414,276...4,422,283
JBrowse link
G B4galnt4 beta-1,4-N-acetyl-galactosaminyl transferase 4 decreases expression ISO Arbutin results in decreased expression of B4GALNT4 mRNA CTD PMID:17103032 NCBI chr 1:213,870,328...213,881,233
Ensembl chr 1:213,870,502...213,881,917
JBrowse link
G Bag5 BAG cochaperone 5 decreases expression ISO Arbutin results in decreased expression of BAG5 mRNA CTD PMID:17103032 NCBI chr 6:136,180,640...136,185,651
Ensembl chr 6:136,182,006...136,185,651
JBrowse link
G Bcas2 BCAS2, pre-mRNA processing factor increases expression ISO Arbutin results in increased expression of BCAS2 mRNA CTD PMID:17103032 NCBI chr 2:205,662,633...205,670,514
Ensembl chr 2:205,662,588...205,670,511
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase decreases expression ISO Arbutin results in decreased expression of BCKDK mRNA CTD PMID:17103032 NCBI chr 1:199,351,628...199,356,299
Ensembl chr 1:199,351,628...199,356,881
JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B decreases expression ISO Arbutin results in decreased expression of BMPR1B mRNA CTD PMID:17103032 NCBI chr 2:247,392,195...247,662,026
Ensembl chr 2:247,403,920...247,446,882
JBrowse link
G Bnip2 BCL2 interacting protein 2 increases expression ISO Arbutin results in increased expression of BNIP2 mRNA CTD PMID:17103032 NCBI chr 8:76,400,333...76,426,307
Ensembl chr 8:76,400,341...76,426,503
JBrowse link
G Brsk1 BR serine/threonine kinase 1 decreases expression ISO Arbutin results in decreased expression of BRSK1 mRNA CTD PMID:17103032 NCBI chr 1:72,701,281...72,727,061
Ensembl chr 1:72,701,610...72,727,112
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression ISO Arbutin results in decreased expression of BST2 mRNA CTD PMID:17103032 NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
JBrowse link
G C1qb complement C1q B chain decreases expression ISO Arbutin results in decreased expression of C1QB mRNA CTD PMID:17103032 NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
JBrowse link
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 decreases expression ISO Arbutin results in decreased expression of CACNG7 mRNA CTD PMID:17103032 NCBI chr 1:64,374,547...64,405,380
Ensembl chr 1:64,374,603...64,405,149
JBrowse link
G Capns2 calpain, small subunit 2 increases expression ISO Arbutin results in increased expression of CAPNS2 mRNA CTD PMID:17103032 NCBI chr19:15,485,258...15,486,200 JBrowse link
G Casp8 caspase 8 decreases expression ISO Arbutin results in decreased expression of CASP8 mRNA CTD PMID:17103032 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cbx6 chromobox 6 decreases expression ISO Arbutin results in decreased expression of CBX6 mRNA CTD PMID:17103032 NCBI chr 7:121,047,996...121,058,109
Ensembl chr 7:121,050,302...121,058,029
JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 increases expression ISO Arbutin results in increased expression of CCAR1 mRNA CTD PMID:17103032 NCBI chr20:32,373,443...32,416,044
Ensembl chr20:32,373,443...32,416,044
JBrowse link
G Ccdc170 coiled-coil domain containing 170 decreases expression ISO Arbutin results in decreased expression of CCDC170 mRNA CTD PMID:17103032 NCBI chr 1:42,216,594...42,256,837
NCBI chr 1:41,033,284...41,133,299
Ensembl chr 1:41,034,308...41,126,043
JBrowse link
G Ccdc28b coiled coil domain containing 28B decreases expression ISO Arbutin results in decreased expression of CCDC28B mRNA CTD PMID:17103032 NCBI chr 5:147,823,446...147,828,449
Ensembl chr 5:147,823,447...147,828,449
JBrowse link
G Ccnyl1 cyclin Y-like 1 increases expression ISO Arbutin results in increased expression of CCNYL1 mRNA CTD PMID:17103032 NCBI chr 9:71,398,186...71,434,581
Ensembl chr 9:71,398,710...71,434,493
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 increases expression ISO Arbutin results in increased expression of CCT8 mRNA CTD PMID:17103032 NCBI chr11:27,130,172...27,141,881
Ensembl chr11:27,130,172...27,141,881
JBrowse link
G Cd151 CD151 molecule (Raph blood group) decreases expression ISO Arbutin results in decreased expression of CD151 mRNA CTD PMID:17103032 NCBI chr 1:214,446,659...214,450,668
Ensembl chr 1:214,009,784...214,013,765
Ensembl chr 1:214,009,784...214,013,765
JBrowse link
G Cd160 CD160 molecule decreases expression ISO Arbutin results in decreased expression of CD160 mRNA CTD PMID:17103032 NCBI chr 2:198,933,681...198,965,380
Ensembl chr 2:198,935,133...198,942,732
JBrowse link
G Cd2bp2 Cd2 (cytoplasmic tail) binding protein 2 decreases expression ISO Arbutin results in decreased expression of CD2BP2 mRNA CTD PMID:17103032 NCBI chr 1:198,635,445...198,641,195
Ensembl chr 1:198,635,447...198,638,944
JBrowse link
G Cd3g CD3g molecule decreases expression ISO Arbutin results in decreased expression of CD3G mRNA CTD PMID:17103032 NCBI chr 8:49,274,553...49,280,943
Ensembl chr 8:49,274,960...49,280,901
JBrowse link
G Cdin1 CDAN1 interacting nuclease 1 increases expression ISO Arbutin results in increased expression of CDIN1 mRNA CTD PMID:17103032 NCBI chr 3:107,142,734...107,347,381
Ensembl chr 3:107,142,762...107,348,650
JBrowse link
G Cdk16 cyclin-dependent kinase 16 decreases expression ISO Arbutin results in decreased expression of CDK16 mRNA CTD PMID:17103032 NCBI chr  X:1,707,285...1,718,821
Ensembl chr  X:1,707,289...1,718,637
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 decreases expression ISO Arbutin results in decreased expression of CEACAM1 mRNA CTD PMID:17103032 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Cfap161 cilia and flagella associated protein 161 decreases expression ISO Arbutin results in decreased expression of CFAP161 mRNA CTD PMID:17103032 NCBI chr 1:145,907,093...145,931,583
Ensembl chr 1:145,907,094...145,931,583
JBrowse link
G Cfap70 cilia and flagella associated protein 70 decreases expression ISO Arbutin results in decreased expression of CFAP70 mRNA CTD PMID:17103032 NCBI chr15:4,285,049...4,350,707
Ensembl chr15:4,285,052...4,350,714
JBrowse link
G Clec4b2 C-type lectin domain family 4, member B2 decreases expression ISO Arbutin results in decreased expression of CLEC4C mRNA CTD PMID:17103032 NCBI chr 4:156,107,720...156,131,226
Ensembl chr 4:156,107,620...156,131,583
JBrowse link
G Cnksr2 connector enhancer of kinase suppressor of Ras 2 decreases expression ISO Arbutin results in decreased expression of CNKSR2 mRNA CTD PMID:17103032 NCBI chr  X:39,711,001...39,953,860
Ensembl chr  X:39,711,201...39,951,847
JBrowse link
G Col17a1 collagen type XVII alpha 1 chain decreases expression ISO Arbutin results in decreased expression of COL17A1 mRNA CTD PMID:17103032 NCBI chr 1:267,416,681...267,465,049
Ensembl chr 1:267,417,459...267,463,705
JBrowse link
G Cpb1 carboxypeptidase B1 decreases expression ISO Arbutin results in decreased expression of CPB1 mRNA CTD PMID:17103032 NCBI chr 2:105,059,293...105,089,682
Ensembl chr 2:105,059,426...105,089,659
JBrowse link
G Cpe carboxypeptidase E increases expression ISO Arbutin results in increased expression of CPE mRNA CTD PMID:17103032 NCBI chr16:26,906,716...27,014,811
Ensembl chr16:26,906,716...27,014,813
JBrowse link
G Cpne5 copine 5 increases expression ISO Arbutin results in increased expression of CPNE5 mRNA CTD PMID:17103032 NCBI chr20:6,419,033...6,500,843
Ensembl chr20:6,419,033...6,500,523
JBrowse link
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 increases expression ISO Arbutin results in increased expression of CYP2U1 mRNA CTD PMID:17103032 NCBI chr 2:236,414,131...236,431,650
Ensembl chr 2:236,414,135...236,431,683
JBrowse link
G Cyrib CYFIP related Rac1 interactor B increases expression ISO Arbutin results in increased expression of CYRIB mRNA CTD PMID:17103032 NCBI chr 7:104,514,566...104,641,875
Ensembl chr 7:104,516,391...104,556,419
JBrowse link
G Ddx46 DEAD-box helicase 46 increases expression ISO Arbutin results in increased expression of DDX46 mRNA CTD PMID:17103032 NCBI chr17:9,475,275...9,519,545
Ensembl chr17:9,475,538...9,519,595
JBrowse link
G Diaph2 diaphanous-related formin 2 decreases expression ISO Arbutin results in decreased expression of DIAPH2 mRNA CTD PMID:17103032 NCBI chr  X:99,722,910...100,363,228 JBrowse link
G Dlgap4 DLG associated protein 4 increases expression ISO Arbutin results in increased expression of DLGAP4 mRNA CTD PMID:17103032 NCBI chr 3:152,752,091...152,846,118
Ensembl chr 3:152,752,091...152,846,118
JBrowse link
G Dlx1 distal-less homeobox 1 decreases expression ISO Arbutin results in decreased expression of DLX1 mRNA CTD PMID:17103032 NCBI chr 3:58,164,931...58,169,521
Ensembl chr 3:58,164,931...58,169,521
JBrowse link
G Dmxl1 Dmx-like 1 decreases expression ISO Arbutin results in decreased expression of DMXL1 mRNA CTD PMID:17103032 NCBI chr18:44,468,762...44,644,769
Ensembl chr18:44,468,784...44,642,050
JBrowse link
G Dnah7 dynein, axonemal, heavy chain 7 decreases expression ISO Arbutin results in decreased expression of DNAH7 mRNA CTD PMID:17103032 NCBI chr 9:60,070,087...60,330,121
NCBI chr 9:59,564,253...59,595,347
Ensembl chr 9:60,070,739...60,330,125
Ensembl chr 9:60,070,739...60,330,125
JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 decreases expression ISO Arbutin results in decreased expression of DNAI3 mRNA CTD PMID:17103032 NCBI chr 2:251,912,432...251,970,699
Ensembl chr 2:251,912,368...251,970,768
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Arbutin results in increased expression of DNAJB9 mRNA CTD PMID:17103032 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Dpp7 dipeptidylpeptidase 7 decreases expression ISO Arbutin results in decreased expression of DPP7 mRNA CTD PMID:17103032 NCBI chr 3:2,569,135...2,573,387
Ensembl chr 3:2,569,135...2,573,387
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases expression ISO Arbutin results in decreased expression of DPYSL2 mRNA CTD PMID:17103032 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Ece1 endothelin converting enzyme 1 increases expression ISO Arbutin results in increased expression of ECE1 mRNA CTD PMID:17103032 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 increases expression ISO Arbutin results in increased expression of EEPD1 mRNA CTD PMID:17103032 NCBI chr 8:26,651,241...26,758,330
Ensembl chr 8:26,652,121...26,758,325
JBrowse link
G Efhc2 EF-hand domain containing 2 decreases expression ISO Arbutin results in decreased expression of EFHC2 mRNA CTD PMID:17103032 NCBI chr  X:5,825,551...6,026,398
Ensembl chr  X:5,825,711...6,026,398
JBrowse link
G Efl1 elongation factor like GTPase 1 increases expression ISO Arbutin results in increased expression of EFL1 mRNA CTD PMID:17103032 NCBI chr 1:144,601,425...144,740,634
Ensembl chr 1:144,601,410...144,740,735
JBrowse link
G Efna3 ephrin A3 decreases expression ISO Arbutin results in decreased expression of EFNA3 mRNA CTD PMID:17103032 NCBI chr 2:188,636,304...188,645,302
Ensembl chr 2:188,637,852...188,645,196
JBrowse link
G Efs embryonal Fyn-associated substrate decreases expression ISO Arbutin results in decreased expression of EFS mRNA CTD PMID:17103032 NCBI chr15:33,579,952...33,590,217
Ensembl chr15:33,578,381...33,589,522
JBrowse link
G Eid1 EP300 interacting inhibitor of differentiation 1 increases expression ISO Arbutin results in increased expression of EID1 mRNA CTD PMID:17103032 NCBI chr 3:117,938,500...117,940,219
Ensembl chr 3:117,938,500...117,940,219