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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dihydroactinidiolide
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Accession:CHEBI:176780 term browser browse the term
Synonyms:exact_synonym: 4,4,7a-trimethyl-6,7-dihydro-5H-1-benzouran-2-one
 related_synonym: Actinidiolide, dihydro-;   Formula=C11H16O2;   InChI=1S/C11H16O2/c1-10(2)5-4-6-11(3)8(10)7-9(12)13-11/h7H,4-6H2,1-3H3;   InChIKey=IMKHDCBNRDRUEB-UHFFFAOYSA-N;   SMILES=O1C2(C(C(CCC2)(C)C)=CC1=O)C
 xref: CAS:15356-74-8;   Chemspider:25323;   HMDB:HMDB0035240
 xref_mesh: MESH:C010711



show annotations for term's descendants           Sort by:
dihydroactinidiolide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO dihydroactinidiolide inhibits the reaction [Colchicine results in increased activity of ACHE protein]; dihydroactinidiolide inhibits the reaction [Glutamic Acid results in increased activity of ACHE protein]
dihydroactinidiolide inhibits the reaction [Scopolamine results in increased activity of ACHE protein]
CTD PMID:33617922 PMID:34371027 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO dihydroactinidiolide inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of BAX protein]; dihydroactinidiolide inhibits the reaction [Colchicine results in increased expression of BAX protein]; dihydroactinidiolide inhibits the reaction [Dithionite results in increased expression of BAX protein]; dihydroactinidiolide inhibits the reaction [Glutamic Acid results in increased expression of BAX protein]
dihydroactinidiolide inhibits the reaction [Scopolamine results in increased expression of BAX protein]
CTD PMID:33617922 PMID:34371027 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO dihydroactinidiolide inhibits the reaction [amyloid beta-protein (25-35) results in decreased expression of BCL2 protein]; dihydroactinidiolide inhibits the reaction [Colchicine results in decreased expression of BCL2 protein]; dihydroactinidiolide inhibits the reaction [Dithionite results in decreased expression of BCL2 protein]; dihydroactinidiolide inhibits the reaction [Glutamic Acid results in decreased expression of BCL2 protein]
dihydroactinidiolide inhibits the reaction [Scopolamine results in decreased expression of BCL2 protein]
CTD PMID:33617922 PMID:34371027 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO dihydroactinidiolide inhibits the reaction [Scopolamine results in decreased expression of BDNF mRNA] CTD PMID:34371027 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Casp3 caspase 3 multiple interactions ISO dihydroactinidiolide inhibits the reaction [amyloid beta-protein (25-35) results in increased activity of CASP3 protein]; dihydroactinidiolide inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of CASP3 protein]; dihydroactinidiolide inhibits the reaction [Colchicine results in increased activity of CASP3 protein]; dihydroactinidiolide inhibits the reaction [Colchicine results in increased expression of CASP3 protein]; dihydroactinidiolide inhibits the reaction [Glutamic Acid results in increased expression of CASP3 protein]
dihydroactinidiolide inhibits the reaction [Scopolamine results in increased activity of CASP3 protein]
CTD PMID:33617922 PMID:34371027 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions ISO dihydroactinidiolide inhibits the reaction [Scopolamine results in decreased activity of CAT protein] CTD PMID:34371027 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [dihydroactinidiolide co-treated with amyloid beta-protein (25-35)] results in increased expression of HMOX1 mRNA; [dihydroactinidiolide co-treated with Colchicine] results in increased expression of HMOX1 mRNA; [dihydroactinidiolide co-treated with Dithionite] results in increased expression of HMOX1 mRNA; [dihydroactinidiolide co-treated with Glutamic Acid] results in increased expression of HMOX1 mRNA CTD PMID:33617922 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [dihydroactinidiolide co-treated with amyloid beta-protein (25-35)] results in increased expression of NFE2L2 mRNA; [dihydroactinidiolide co-treated with Colchicine] results in increased expression of NFE2L2 mRNA; [dihydroactinidiolide co-treated with Dithionite] results in increased expression of NFE2L2 mRNA; [dihydroactinidiolide co-treated with Glutamic Acid] results in increased expression of NFE2L2 mRNA CTD PMID:33617922 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Syp synaptophysin multiple interactions ISO dihydroactinidiolide inhibits the reaction [Scopolamine results in decreased expression of SYP mRNA] CTD PMID:34371027 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    chemical entity 19840
      atom 19809
        nonmetal atom 19747
          oxygen atom 19520
            oxygen molecular entity 19490
              organooxygen compound 19137
                oxacycle 17819
                  benzofurans 3273
                    dihydroactinidiolide 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    main group molecular entity 19759
                      p-block molecular entity 19759
                        carbon group molecular entity 19708
                          organic molecular entity 19705
                            organic molecule 19658
                              organic cyclic compound 19471
                                organic heterocyclic compound 18862
                                  organic heteropolycyclic compound 18301
                                    benzofurans 3273
                                      dihydroactinidiolide 9
paths to the root