|
G
|
Eif4e
|
eukaryotic translation initiation factor 4E
|
affects binding multiple interactions
|
ISO
|
7-methylguanosine 5'-diphosphate analog binds to EIF4E protein 7-methylguanosine triphosphate inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; 7-methylguanosine-5'-monophosphate inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; Guanosine analog inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; Quinolones inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; Sulfonamides inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]
|
CTD |
PMID:27592390 |
|
NCBI chr 2:229,736,309...229,772,628
Ensembl chr 2:227,066,673...227,098,683
|
|
|
G
|
Hsd17b2
|
hydroxysteroid (17-beta) dehydrogenase 2
|
affects binding
|
ISO
|
acetoacetyl CoA binds to HSD17B2 protein
|
CTD |
PMID:25526675 |
|
NCBI chr19:62,662,320...62,733,944
Ensembl chr19:45,753,574...45,825,202
|
|
|
G
|
Acly
|
ATP citrate lyase
|
increases abundance affects abundance
|
ISO
|
ACLY protein results in increased abundance of Acetyl Coenzyme A ACLY protein affects the abundance of Acetyl Coenzyme A
|
CTD |
PMID:28077572 PMID:36933457 |
|
NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,412,049...85,463,320
|
|
G
|
App
|
amyloid beta precursor protein
|
affects localization increases secretion multiple interactions
|
ISO
|
APP protein affects the localization of Acetyl Coenzyme A Acetyl Coenzyme A results in increased secretion of APP protein modified form Acetyl Coenzyme A inhibits the reaction [Hydrogen Peroxide results in decreased secretion of APP protein modified form] IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A]
|
CTD |
PMID:16122837 PMID:22906069 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561
|
|
G
|
Crat
|
carnitine O-acetyltransferase
|
decreases activity
|
EXP
|
Acetyl Coenzyme A deficiency results in decreased activity of CRAT protein
|
CTD |
PMID:8075222 |
|
NCBI chr 3:34,073,504...34,087,099
Ensembl chr 3:13,675,684...13,689,255
|
|
G
|
Ercc6
|
ERCC excision repair 6, chromatin remodeling factor
|
decreases abundance multiple interactions
|
ISO
|
ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A 3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]
|
CTD |
PMID:25440059 |
|
NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,765,013...7,835,587
|
|
G
|
G6pc1
|
glucose-6-phosphatase catalytic subunit 1
|
multiple interactions
|
ISO
|
[Fluoxetine results in decreased expression of G6PC1 protein] which results in increased abundance of Acetyl Coenzyme A
|
CTD |
PMID:33179799 |
|
NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,257,668...86,333,804
|
|
G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
ISO
|
IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A]
|
CTD |
PMID:16122837 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
|
|
G
|
Kat2b
|
lysine acetyltransferase 2B
|
affects binding
|
ISO
|
Acetyl Coenzyme A binds to KAT2B protein
|
CTD |
PMID:28077572 |
|
NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,562,288...6,667,064
|
|
G
|
Metrnl
|
meteorin-like, glial cell differentiation regulator
|
multiple interactions
|
ISO
|
METRNL protein inhibits the reaction [Dietary Fats results in decreased abundance of Acetyl Coenzyme A]
|
CTD |
PMID:30213948 |
|
NCBI chr10:107,462,148...107,476,143
Ensembl chr10:106,963,880...106,977,869
|
|
G
|
Nat1
|
N-acetyltransferase 1
|
multiple interactions affects binding
|
ISO
|
[NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; Acetyl Coenzyme A inhibits the reaction [Cyanamide results in decreased activity of NAT1 protein]; Acetyl Coenzyme A inhibits the reaction [Iodoacetamide results in decreased activity of NAT1 protein] Acetyl Coenzyme A binds to NAT1 protein
|
CTD |
PMID:20545351 PMID:22835378 |
|
NCBI chr16:26,984,882...27,005,194
Ensembl chr16:22,208,194...22,238,520
|
|
G
|
Nat2
|
N-acetyltransferase 2
|
multiple interactions
|
ISO
|
[NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]
|
CTD |
PMID:20545351 |
|
NCBI chr16:26,974,874...27,005,191
Ensembl chr16:22,208,194...22,238,520
|
|
G
|
Nqo1
|
NAD(P)H quinone dehydrogenase 1
|
multiple interactions
|
ISO
|
[NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone
|
CTD |
PMID:20545351 |
|
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557
|
|
|
G
|
Echs1
|
enoyl-CoA hydratase, short chain 1
|
increases abundance
|
ISO
|
ECHS1 gene mutant form results in increased abundance of acryloyl-coenzyme A
|
CTD |
PMID:25125611 |
|
NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:194,895,036...194,903,884
|
|
G
|
Hibch
|
3-hydroxyisobutyryl-CoA hydrolase
|
increases abundance
|
ISO
|
HIBCH gene mutant form results in increased abundance of acryloyl-coenzyme A
|
CTD |
PMID:25125611 |
|
NCBI chr 9:56,082,082...56,161,796
Ensembl chr 9:48,590,099...48,669,824
|
|
|
G
|
Abcc1
|
ATP binding cassette subfamily C member 1
|
multiple interactions affects binding
|
ISO
|
estradiol-17 beta-glucuronide inhibits the reaction [Adenosine Diphosphate binds to ABCC1 protein mutant form]; estradiol-17 beta-glucuronide inhibits the reaction [Adenosine Diphosphate binds to ABCC1 protein]; Vanadates promotes the reaction [Adenosine Diphosphate binds to ABCC1 protein] Adenosine Diphosphate binds to ABCC1 protein; Adenosine Diphosphate binds to ABCC1 protein mutant form
|
CTD |
PMID:18336795 |
|
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:531,812...655,114
|
|
G
|
Ahr
|
aryl hydrocarbon receptor
|
multiple interactions
|
EXP
|
Adenosine Diphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein]
|
CTD |
PMID:1848756 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
|
|
G
|
Ak1
|
adenylate kinase 1
|
increases abundance
|
ISO
|
AK1 protein results in increased abundance of Adenosine Diphosphate
|
CTD |
PMID:11390963 |
|
NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041
|
|
G
|
Alb
|
albumin
|
decreases secretion multiple interactions
|
ISO
|
Adenosine Diphosphate results in decreased secretion of ALB protein Aspirin inhibits the reaction [Adenosine Diphosphate results in decreased secretion of ALB protein]
|
CTD |
PMID:17303692 |
|
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836
|
|
G
|
App
|
amyloid beta precursor protein
|
multiple interactions increases abundance
|
ISO
|
PF-06840003 inhibits the reaction [APP protein mutant form results in increased abundance of Adenosine Diphosphate] [APP protein mutant form co-treated with PSEN1 protein mutant form] results in increased abundance of Adenosine Diphosphate; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in increased abundance of Adenosine Diphosphate]
|
CTD |
PMID:39172838 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561
|
|
G
|
Axl
|
Axl receptor tyrosine kinase
|
decreases response to substance
|
ISO
|
AXL protein results in decreased susceptibility to Adenosine Diphosphate
|
CTD |
PMID:15733062 |
|
NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:81,265,088...81,296,265
|
|
G
|
Cat
|
catalase
|
multiple interactions
|
EXP
|
CAT protein inhibits the reaction [Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein]
|
CTD |
PMID:16781456 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
|
|
G
|
Cd40lg
|
CD40 ligand
|
increases expression multiple interactions
|
ISO
|
Adenosine Diphosphate results in increased expression of CD40LG protein clopidogrel inhibits the reaction [Adenosine Diphosphate results in increased expression of CD40LG protein]
|
CTD |
PMID:11297035 PMID:17043144 |
|
NCBI chr X:140,164,341...140,176,057
Ensembl chr X:135,126,969...135,138,306
|
|
G
|
Cftr
|
CF transmembrane conductance regulator
|
multiple interactions
|
ISO
|
Adenosine Diphosphate binds to and results in decreased activity of CFTR protein; P(1),P(5)-di(adenosine-5'-)pentaphosphate inhibits the reaction [Adenosine Diphosphate binds to and results in decreased activity of CFTR protein]
|
CTD |
PMID:15684079 |
|
NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:46,560,885...46,728,756
|
|
G
|
Chordc1
|
cysteine and histidine rich domain containing 1
|
multiple interactions
|
ISO
|
Adenosine Diphosphate binds to and affects the folding of CHORDC1 protein; Adenosine Diphosphate promotes the reaction [CHORDC1 protein binds to CHORDC1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein]
|
CTD |
PMID:23184943 |
|
NCBI chr 8:23,650,721...23,674,786
Ensembl chr 8:15,374,471...15,399,162
|
|
G
|
Cyp2c6
|
cytochrome P450, family 2, subfamily C, polypeptide 6
|
multiple interactions
|
ISO
|
CYP2C19 gene affects the susceptibility to [Adenosine Diphosphate co-treated with clopidogrel]; CYP2C19 gene SNP affects the reaction [Adenosine Diphosphate results in increased expression of SELP protein]; CYP2C19 gene SNP affects the susceptibility to [Adenosine Diphosphate co-treated with Arachidonic Acid]
|
CTD |
PMID:16772608 PMID:18004210 PMID:18394438 |
|
NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:237,693,094...238,057,596
|
|
G
|
Dtymk
|
deoxythymidylate kinase
|
multiple interactions
|
ISO
|
DTYMK protein binds to [N1-(4-bis(pivaloyloxymethyl)phosphinylbuten-2-yl)thymine co-treated with Adenosine Diphosphate]
|
CTD |
PMID:21128666 |
|
NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870
|
|
G
|
Dusp1
|
dual specificity phosphatase 1
|
multiple interactions
|
ISO
|
Adenosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of DUSP1 protein]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in decreased expression of DUSP1 protein]]
|
CTD |
PMID:32941855 |
|
NCBI chr10:17,184,853...17,187,646
|
|
G
|
Dusp6
|
dual specificity phosphatase 6
|
multiple interactions
|
ISO
|
Adenosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of DUSP6 protein]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in decreased expression of DUSP6 protein]]
|
CTD |
PMID:32941855 |
|
NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:34,092,943...34,097,185
|
|
G
|
Epha4
|
Eph receptor A4
|
increases phosphorylation multiple interactions
|
ISO
|
Adenosine Diphosphate results in increased phosphorylation of EPHA4 protein Benzoic Acid analog inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of EPHA4 protein]
|
CTD |
PMID:22273509 |
|
NCBI chr 9:86,263,982...86,406,744
Ensembl chr 9:78,815,460...78,958,139
|
|
G
|
Ern1
|
endoplasmic reticulum to nucleus signaling 1
|
multiple interactions decreases activity
|
ISO
|
Adenosine Diphosphate inhibits the reaction [ERN1 protein binds to ERN1 protein] Adenosine Diphosphate results in decreased activity of ERN1 protein
|
CTD |
PMID:25164867 |
|
NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029
|
|
G
|
F2
|
coagulation factor II, thrombin
|
increases abundance multiple interactions
|
ISO
|
F2 protein results in increased abundance of Adenosine Diphosphate Quercetin inhibits the reaction [F2 protein results in increased abundance of Adenosine Diphosphate]; resveratrol inhibits the reaction [F2 protein results in increased abundance of Adenosine Diphosphate]
|
CTD |
PMID:15342215 |
|
NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:77,596,198...77,609,486
|
|
G
|
Fga
|
fibrinogen alpha chain
|
multiple interactions increases secretion
|
ISO
|
Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of FGA protein]
|
CTD |
PMID:17303692 |
|
NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:168,374,120...168,381,528
|
|
G
|
Fgb
|
fibrinogen beta chain
|
decreases secretion multiple interactions
|
ISO
|
Adenosine Diphosphate results in decreased secretion of FGB protein Aspirin inhibits the reaction [Adenosine Diphosphate results in decreased secretion of FGB protein]
|
CTD |
PMID:17303692 |
|
NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:168,394,916...168,405,979
|
|
G
|
Fgg
|
fibrinogen gamma chain
|
increases secretion multiple interactions
|
ISO
|
Adenosine Diphosphate results in increased secretion of FGG protein Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of FGG protein]
|
CTD |
PMID:17303692 |
|
NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:168,355,013...168,362,322
|
|
G
|
Gapdh
|
glyceraldehyde-3-phosphate dehydrogenase
|
multiple interactions
|
ISO
|
Adenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]
|
CTD |
PMID:15788719 |
|
NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:157,962,343...157,966,235
|
|
G
|
Gas6
|
growth arrest specific 6
|
increases response to substance
|
ISO
|
GAS6 protein results in increased susceptibility to Adenosine Diphosphate
|
CTD |
PMID:15733062 |
|
NCBI chr16:82,747,676...82,778,090
Ensembl chr16:76,045,426...76,075,904
|
|
G
|
H2ax
|
H2A.X variant histone
|
multiple interactions
|
ISO
|
Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]]; U 0126 inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]]
|
CTD |
PMID:32941855 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:44,671,786...44,673,239 Ensembl chr 4:44,671,786...44,673,239
|
|
G
|
Hras
|
HRas proto-oncogene, GTPase
|
multiple interactions
|
ISO
|
Adenosine Diphosphate binds to and affects the folding of HRAS protein
|
CTD |
PMID:16388579 |
|
NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615
|
|
G
|
Hsp90aa1
|
heat shock protein 90 alpha family class A member 1
|
multiple interactions
|
ISO
|
Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]
|
CTD |
PMID:23184943 |
|
NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:129,702,383...129,707,268
|
|
G
|
Idh2
|
isocitrate dehydrogenase (NADP(+)) 2
|
multiple interactions increases abundance
|
ISO
|
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Adenosine Diphosphate]
|
CTD |
PMID:27469509 |
|
NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025
|
|
G
|
Il6
|
interleukin 6
|
increases expression multiple interactions
|
ISO
|
Adenosine Diphosphate results in increased expression of IL6 protein MRS 2211 inhibits the reaction [Adenosine Diphosphate results in increased expression of IL6 protein]
|
CTD |
PMID:24849676 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
|
|
G
|
Itga2
|
integrin subunit alpha 2
|
multiple interactions
|
ISO
|
ITGA2 gene SNP affects the susceptibility to [Aspirin co-treated with clopidogrel co-treated with Adenosine Diphosphate]
|
CTD |
PMID:16214444 |
|
NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
|
|
G
|
Itga2b
|
integrin subunit alpha 2b
|
multiple interactions
|
ISO
|
cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]]
|
CTD |
PMID:18404433 |
|
NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168
|
|
G
|
Itgb1bp2
|
integrin subunit beta 1 binding protein 2
|
multiple interactions
|
ISO
|
Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to ITGB1BP2 protein]; Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]
|
CTD |
PMID:23184943 |
|
NCBI chr X:66,572,537...66,577,174
Ensembl chr X:66,572,537...66,577,174
|
|
G
|
Itgb3
|
integrin subunit beta 3
|
multiple interactions
|
ISO
|
cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]]
|
CTD |
PMID:18404433 |
|
NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679
|
|
G
|
Mapk1
|
mitogen activated protein kinase 1
|
increases phosphorylation multiple interactions
|
ISO
|
Adenosine Diphosphate results in increased phosphorylation of MAPK1 protein Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased phosphorylation of MAPK1 protein]]
|
CTD |
PMID:15034929 PMID:32941855 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
|
|
G
|
Mapk3
|
mitogen activated protein kinase 3
|
increases phosphorylation multiple interactions
|
ISO
|
Adenosine Diphosphate results in increased phosphorylation of MAPK3 protein Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased phosphorylation of MAPK3 protein]]
|
CTD |
PMID:15034929 PMID:32941855 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
|
|
G
|
Mapk8
|
mitogen-activated protein kinase 8
|
multiple interactions
|
ISO
|
Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK8 protein]
|
CTD |
PMID:24466103 |
|
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981
|
|
G
|
Mapk9
|
mitogen-activated protein kinase 9
|
multiple interactions
|
ISO
|
Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK9 protein]
|
CTD |
PMID:24466103 |
|
NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,169,675...34,210,178
|
|
G
|
Mapt
|
microtubule-associated protein tau
|
multiple interactions increases abundance
|
ISO
|
PF-06840003 inhibits the reaction [MAPT protein mutant form results in increased abundance of Adenosine Diphosphate]
|
CTD |
PMID:39172838 |
|
NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,138,627...89,236,129
|
|
G
|
Mertk
|
MER proto-oncogene, tyrosine kinase
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increases response to substance
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ISO
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MERTK protein results in increased susceptibility to Adenosine Diphosphate
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CTD |
PMID:15733062 |
|
NCBI chr 3:136,391,936...136,498,366
Ensembl chr 3:115,939,351...116,046,554
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G
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Nos2
|
nitric oxide synthase 2
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multiple interactions
|
ISO
|
NOS2 protein affects the susceptibility to [Phenylephrine co-treated with Adenosine Diphosphate]
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CTD |
PMID:11498454 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210
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G
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Nt5e
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5' nucleotidase, ecto
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decreases activity
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ISO
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Adenosine Diphosphate analog results in decreased activity of NT5E protein
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CTD |
PMID:18404487 |
|
NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881
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G
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P2ry12
|
purinergic receptor P2Y12
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affects response to substance increases response to substance multiple interactions
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ISO EXP
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P2RY12 gene polymorphism affects the susceptibility to Adenosine Diphosphate; P2RY12 protein affects the susceptibility to Adenosine Diphosphate P2RY12 protein results in increased susceptibility to Adenosine Diphosphate Epinephrine inhibits the reaction [P2RY12 gene mutant form results in decreased susceptibility to Adenosine Diphosphate] P2RY12 protein affects the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]
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CTD |
PMID:11196645 PMID:11413167 PMID:18404433 PMID:23849096 |
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NCBI chr 2:145,631,487...145,673,194
Ensembl chr 2:143,481,430...143,523,361
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G
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Pdgfb
|
platelet derived growth factor subunit B
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increases secretion multiple interactions
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ISO
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Adenosine Diphosphate results in increased secretion of PDGFB protein Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of PDGFB protein]
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CTD |
PMID:17303692 |
|
NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:111,540,345...111,557,984
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G
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Pf4
|
platelet factor 4
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increases secretion multiple interactions
|
ISO
|
Adenosine Diphosphate results in increased secretion of PF4 protein silidianin inhibits the reaction [Adenosine Diphosphate results in increased secretion of PF4 protein]; Silybin inhibits the reaction [Adenosine Diphosphate results in increased secretion of PF4 protein]; silychristin inhibits the reaction [Adenosine Diphosphate results in increased secretion of PF4 protein]
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CTD |
PMID:19428933 PMID:29439388 |
|
NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,298,308...17,299,365
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G
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Pfkm
|
phosphofructokinase, muscle
|
multiple interactions
|
ISO
|
Adenosine Diphosphate inhibits the reaction [resveratrol results in decreased activity of PFKM protein]
|
CTD |
PMID:23454376 |
|
NCBI chr 7:131,100,684...131,138,250
Ensembl chr 7:129,221,653...129,259,192
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G
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Pgp
|
phosphoglycolate phosphatase
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decreases phosphorylation
|
ISO
|
PGP protein results in decreased phosphorylation of Adenosine Diphosphate
|
CTD |
PMID:24338473 |
|
NCBI chr10:13,495,232...13,497,858
Ensembl chr10:13,494,291...13,497,858
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G
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Ppbp
|
pro-platelet basic protein
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increases secretion
|
ISO
|
Adenosine Diphosphate results in increased secretion of PPBP protein
|
CTD |
PMID:19428933 |
|
NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
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G
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Ppp5c
|
protein phosphatase 5, catalytic subunit
|
multiple interactions
|
ISO
|
Adenosine Diphosphate binds to and affects the folding of PPP5C protein
|
CTD |
PMID:23184943 |
|
NCBI chr 1:86,818,297...86,842,505
Ensembl chr 1:77,690,208...77,714,456
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G
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Psen1
|
presenilin 1
|
multiple interactions
|
ISO
|
[APP protein mutant form co-treated with PSEN1 protein mutant form] results in increased abundance of Adenosine Diphosphate; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in increased abundance of Adenosine Diphosphate]
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CTD |
PMID:39172838 |
|
NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:103,323,120...103,371,650
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G
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Ptpn1
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protein tyrosine phosphatase, non-receptor type 1
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increases glutathionylation multiple interactions
|
EXP
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Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein CAT protein inhibits the reaction [Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein]
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CTD |
PMID:16781456 |
|
NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:156,638,769...156,687,504
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G
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Selp
|
selectin P
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multiple interactions increases expression
|
ISO
|
cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; CYP2C19 gene SNP affects the reaction [Adenosine Diphosphate results in increased expression of SELP protein]; Heparin promotes the reaction [Adenosine Diphosphate affects the localization of SELP protein]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]]; P2RY12 protein affects the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; Quercetin inhibits the reaction [Adenosine Diphosphate results in increased expression of SELP protein]
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CTD |
PMID:9740346 PMID:18394438 PMID:18404433 PMID:23249183 |
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NCBI chr13:79,009,379...79,044,994
Ensembl chr13:76,476,295...76,511,845
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G
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Sirt3
|
sirtuin 3
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decreases abundance
|
ISO
|
SIRT3 protein results in decreased abundance of Adenosine Diphosphate
|
CTD |
PMID:23166782 |
|
NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808
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G
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Taldo1
|
transaldolase 1
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increases abundance
|
ISO
|
TALDO1 gene mutant form results in increased abundance of Adenosine Diphosphate
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CTD |
PMID:19436114 |
|
NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974
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G
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Thbs1
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thrombospondin 1
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increases secretion
|
ISO
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Adenosine Diphosphate results in increased secretion of THBS1 protein
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CTD |
PMID:17303692 |
|
NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
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|
G
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Tp53bp1
|
tumor protein p53 binding protein 1
|
multiple interactions
|
ISO
|
Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]]; U 0126 inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]]
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CTD |
PMID:32941855 |
|
NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
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G
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Tyro3
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TYRO3 protein tyrosine kinase
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increases response to substance
|
ISO
|
TYRO3 protein results in increased susceptibility to Adenosine Diphosphate
|
CTD |
PMID:15733062 |
|
NCBI chr 3:127,231,468...127,254,806
Ensembl chr 3:106,777,635...106,797,142
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G
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Vasp
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vasodilator-stimulated phosphoprotein
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increases phosphorylation multiple interactions
|
ISO
|
Adenosine Diphosphate results in increased phosphorylation of VASP protein N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of VASP protein]
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CTD |
PMID:25329809 |
|
NCBI chr 1:88,038,026...88,053,783
Ensembl chr 1:78,910,011...78,925,061
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|
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G
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Adprh
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ADP-ribosylarginine hydrolase
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increases hydrolysis
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ISO
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ADPRH protein results in increased hydrolysis of Adenosine Diphosphate Ribose metabolite
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CTD |
PMID:21498885 |
|
NCBI chr11:62,299,831...62,306,170
Ensembl chr11:62,299,793...62,306,931
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G
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Adprs
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ADP-ribosylserine hydrolase
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increases hydrolysis multiple interactions
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ISO
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ADPRS protein results in increased hydrolysis of Adenosine Diphosphate Ribose metabolite Adenosine Diphosphate Ribose inhibits the reaction [ADPRS protein results in increased hydrolysis of O-Acetyl-ADP-Ribose]
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CTD |
PMID:21498885 |
|
NCBI chr 5:138,614,022...138,619,296
Ensembl chr 5:138,614,022...138,619,296
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|
G
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Nos1
|
nitric oxide synthase 1
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multiple interactions
|
ISO
|
NOS1 protein affects the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased ribosylation of Adenosine Diphosphate Ribose]
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CTD |
PMID:10318960 |
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NCBI chr12:44,276,011...44,456,371
Ensembl chr12:38,626,714...38,710,945
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G
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Trpm2
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transient receptor potential cation channel, subfamily M, member 2
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multiple interactions increases activity
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EXP ISO
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Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]; Clotrimazole inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Flufenamic Acid inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]] Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein 2-aminoethoxydiphenyl borate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Cisplatin promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Eicosapentaenoic Acid promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Eicosapentaenoic Acid promotes the reaction [Cisplatin promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]]]; Cisplatin promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Copper Sulfate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Eicosapentaenoic Acid promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Eicosapentaenoic Acid promotes the reaction [Cisplatin promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]]; ferrous chloride inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; lead nitrate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Mercuric Chloride inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Miconazole inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Selenium Oxides inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein] 4-amylcinnamoylanthranilic acid inhibits the reaction [[Buthionine Sulfoximine co-treated with Adenosine Diphosphate Ribose] results in increased activity of TRPM2 protein]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; [Buthionine Sulfoximine co-treated with Adenosine Diphosphate Ribose] results in increased activity of TRPM2 protein; Glutathione inhibits the reaction [[Buthionine Sulfoximine co-treated with Adenosine Diphosphate Ribose] results in increased activity of TRPM2 protein]; Glutathione inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; TRPM2 protein promotes the reaction [Adenosine Diphosphate Ribose results in increased uptake of Calcium]
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CTD |
PMID:18204483 PMID:20878536 PMID:21900507 PMID:22750002 PMID:33309544 PMID:35395232 More...
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NCBI chr20:10,703,190...10,752,795
Ensembl chr20:10,707,014...10,753,181
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|
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G
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Ppara
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peroxisome proliferator activated receptor alpha
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multiple interactions
|
ISO
|
arachidonyl-coenzyme A binds to and results in increased activity of PPARA protein
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CTD |
PMID:11139385 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
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|
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G
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Kat2b
|
lysine acetyltransferase 2B
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affects binding
|
ISO
|
butyryl-coenzyme A binds to KAT2B protein
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CTD |
PMID:28077572 |
|
NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,562,288...6,667,064
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|
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G
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Casp3
|
caspase 3
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decreases expression
|
ISO
|
Cytidine Diphosphate Choline results in decreased expression of CASP3 protein
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CTD |
PMID:12443983 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
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G
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Icam1
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intercellular adhesion molecule 1
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decreases expression
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EXP
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Cytidine Diphosphate Choline results in decreased expression of ICAM1 mRNA
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CTD |
PMID:16193989 |
|
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438
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G
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Nceh1
|
neutral cholesterol ester hydrolase 1
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multiple interactions
|
ISO
|
NCEH1 protein inhibits the reaction [[Chlorpyrifos metabolite co-treated with Cytidine Diphosphate Choline] results in increased abundance of Platelet Activating Factor]
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CTD |
PMID:18164358 |
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NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588
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G
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Parp1
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poly (ADP-ribose) polymerase 1
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decreases expression
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ISO
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Cytidine Diphosphate Choline results in decreased expression of PARP1 protein modified form
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CTD |
PMID:12443983 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404
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G
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Sirt1
|
sirtuin 1
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increases expression multiple interactions
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EXP
|
Cytidine Diphosphate Choline results in increased expression of SIRT1 protein Cytidine Diphosphate Choline results in increased expression of and results in increased activity of SIRT1 protein
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CTD |
PMID:23600725 |
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NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260
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G
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Acot8
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acyl-CoA thioesterase 8
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affects hydrolysis
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ISO
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ACOT8 protein affects the hydrolysis of Coenzyme A analog
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CTD |
PMID:16141203 |
|
NCBI chr 3:173,950,530...173,962,188
Ensembl chr 3:153,531,193...153,542,851
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G
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Kat2b
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lysine acetyltransferase 2B
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affects binding
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ISO
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Coenzyme A binds to KAT2B protein
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CTD |
PMID:28077572 |
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NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,562,288...6,667,064
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G
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Cd38
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CD38 molecule
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decreases abundance
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ISO
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CD38 gene mutant form results in decreased abundance of Cyclic ADP-Ribose
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CTD |
PMID:23343681 |
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NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
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G
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Homer1
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homer scaffold protein 1
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multiple interactions
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EXP
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HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]]
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CTD |
PMID:12887973 |
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NCBI chr 2:26,279,012...26,388,279
Ensembl chr 2:24,543,093...24,644,785
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G
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Ryr2
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ryanodine receptor 2
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multiple interactions
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EXP
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HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]]
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CTD |
PMID:12887973 |
|
NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
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G
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Hsdl2
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hydroxysteroid dehydrogenase like 2
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multiple interactions
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ISO
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[decanoyl-coenzyme A co-treated with NADP] binds to HSDL2 protein
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CTD |
PMID:25526675 |
|
NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:74,443,872...74,479,839
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G
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Pecr
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peroxisomal trans-2-enoyl-CoA reductase
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multiple interactions
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ISO
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[decanoyl-coenzyme A co-treated with NADP] binds to PECR protein
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CTD |
PMID:25526675 |
|
NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:73,897,880...73,926,511
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G
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Fut8
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fucosyltransferase 8
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multiple interactions decreases activity
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ISO
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Guanosine Diphosphate inhibits the reaction [Mersalyl results in decreased activity of FUT8 protein]; Guanosine Diphosphate inhibits the reaction [p-Chloromercuribenzoic Acid results in decreased activity of FUT8 protein]; Guanosine Diphosphate inhibits the reaction [Phenylglyoxal results in decreased activity of FUT8 protein] Guanosine Diphosphate results in decreased activity of FUT8 protein
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CTD |
PMID:12770769 |
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NCBI chr 6:101,682,354...101,909,784
Ensembl chr 6:95,949,991...96,176,677
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G
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Gmds
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GDP-mannose 4, 6-dehydratase
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affects binding
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ISO
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Guanosine Diphosphate binds to GMDS protein
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CTD |
PMID:25526675 |
|
NCBI chr17:32,304,029...32,830,708
Ensembl chr17:32,095,386...32,621,961
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G
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H2ax
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H2A.X variant histone
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multiple interactions
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ISO
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Guanosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]
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CTD |
PMID:32941855 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:44,671,786...44,673,239 Ensembl chr 4:44,671,786...44,673,239
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G
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Hras
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HRas proto-oncogene, GTPase
|
multiple interactions
|
ISO
|
[Enzyme Inhibitors binds to and results in decreased activity of SOS1 protein] promotes the reaction [HRAS protein binds to Guanosine Diphosphate]; Enzyme Inhibitors inhibits the reaction [SOS1 protein binds to [HRAS protein binds to Guanosine Diphosphate]]
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CTD |
PMID:25825487 |
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NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615
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G
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Htr1a
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5-hydroxytryptamine receptor 1A
|
multiple interactions
|
EXP
|
Guanosine Diphosphate affects the reaction [Serotonin inhibits the reaction [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to HTR1A protein]]
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CTD |
PMID:21126535 |
|
NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:36,694,174...36,695,442
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G
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Kras
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KRAS proto-oncogene, GTPase
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multiple interactions affects binding
|
ISO
|
KRAS protein mutant form inhibits the reaction [SOS1 protein inhibits the reaction [Guanosine Diphosphate binds to KRAS protein]]; SOS1 protein inhibits the reaction [Guanosine Diphosphate binds to KRAS protein] Guanosine Diphosphate binds to KRAS protein; Guanosine Diphosphate binds to KRAS protein mutant form
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CTD |
PMID:28154176 |
|
NCBI chr 4:179,916,255...179,949,613
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G
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Pgp
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phosphoglycolate phosphatase
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decreases phosphorylation
|
ISO
|
PGP protein results in decreased phosphorylation of Guanosine Diphosphate
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CTD |
PMID:24338473 |
|
NCBI chr10:13,495,232...13,497,858
Ensembl chr10:13,494,291...13,497,858
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G
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Rab3a
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RAB3A, member RAS oncogene family
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affects binding multiple interactions
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EXP
|
Guanosine Diphosphate binds to RAB3A protein [alpha-latrotoxin promotes the reaction [RAB3A protein results in increased cleavage of Guanosine Triphosphate]] promotes the reaction [Guanosine Diphosphate binds to RAB3A protein]; [black widow spider venom promotes the reaction [RAB3A protein results in increased cleavage of Guanosine Triphosphate]] promotes the reaction [Guanosine Diphosphate binds to RAB3A protein]
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CTD |
PMID:7929154 |
|
NCBI chr16:18,718,164...18,722,273
Ensembl chr16:18,684,188...18,688,336
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G
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Sos1
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SOS Ras/Rac guanine nucleotide exchange factor 1
|
multiple interactions
|
ISO
|
[Enzyme Inhibitors binds to and results in decreased activity of SOS1 protein] promotes the reaction [HRAS protein binds to Guanosine Diphosphate]; Enzyme Inhibitors inhibits the reaction [SOS1 protein binds to [HRAS protein binds to Guanosine Diphosphate]]; KRAS protein mutant form inhibits the reaction [SOS1 protein inhibits the reaction [Guanosine Diphosphate binds to KRAS protein]]; SOS1 protein inhibits the reaction [Guanosine Diphosphate binds to KRAS protein]
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CTD |
PMID:25825487 PMID:28154176 |
|
NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:14,533,360...14,611,107
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G
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Tp53bp1
|
tumor protein p53 binding protein 1
|
multiple interactions
|
ISO
|
Guanosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]
|
CTD |
PMID:32941855 |
|
NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
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|
|
G
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Idh2
|
isocitrate dehydrogenase (NADP(+)) 2
|
multiple interactions increases abundance
|
ISO
|
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of guanosine diphosphate glucose]
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CTD |
PMID:27469509 |
|
NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025
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|
|
G
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Acat1
|
acetyl-CoA acetyltransferase 1
|
multiple interactions
|
ISO
|
guanosine 5'-O-(2-thiodiphosphate) inhibits the reaction [Serotonin results in increased expression of ACAT1 protein]
|
CTD |
PMID:16157345 |
|
NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:53,979,813...54,008,855
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G
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Trpc6
|
transient receptor potential cation channel, subfamily C, member 6
|
decreases activity
|
ISO
|
guanosine 5'-O-(2-thiodiphosphate) results in decreased activity of TRPC6 protein
|
CTD |
PMID:11179201 |
|
NCBI chr 8:14,044,216...14,148,808
Ensembl chr 8:5,758,935...5,828,092
|
|
|
G
|
Acot4
|
acyl-CoA thioesterase 4
|
affects hydrolysis
|
ISO
|
ACOT4 protein affects the hydrolysis of glutaryl-coenzyme A
|
CTD |
PMID:16141203 |
|
NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:103,668,753...103,673,917
|
|
G
|
Acot8
|
acyl-CoA thioesterase 8
|
affects hydrolysis
|
ISO
|
ACOT8 protein affects the hydrolysis of glutaryl-coenzyme A
|
CTD |
PMID:16141203 |
|
NCBI chr 3:173,950,530...173,962,188
Ensembl chr 3:153,531,193...153,542,851
|
|
|
G
|
Pecr
|
peroxisomal trans-2-enoyl-CoA reductase
|
multiple interactions
|
ISO
|
[hexanoyl-coenzyme A co-treated with NADP] binds to PECR protein
|
CTD |
PMID:25526675 |
|
NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:73,897,880...73,926,511
|
|
|
G
|
H2ax
|
H2A.X variant histone
|
multiple interactions
|
ISO
|
Inosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]
|
CTD |
PMID:32941855 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:44,671,786...44,673,239 Ensembl chr 4:44,671,786...44,673,239
|
|
G
|
Tp53bp1
|
tumor protein p53 binding protein 1
|
multiple interactions
|
ISO
|
Inosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]
|
CTD |
PMID:32941855 |
|
NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
|
|
|
G
|
Kat2b
|
lysine acetyltransferase 2B
|
affects binding
|
ISO
|
isobutyryl-coenzyme A binds to KAT2B protein
|
CTD |
PMID:28077572 |
|
NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,562,288...6,667,064
|
|
|
G
|
Gsta1
|
glutathione S-transferase alpha 1
|
multiple interactions
|
ISO
|
lauroyl-coenzyme A binds to and results in decreased activity of GSTA1 protein
|
CTD |
PMID:10542059 |
|
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:23,703,477...23,720,121
|
|
G
|
Hsdl2
|
hydroxysteroid dehydrogenase like 2
|
multiple interactions
|
ISO
|
[lauroyl-coenzyme A co-treated with NADP] binds to HSDL2 protein
|
CTD |
PMID:25526675 |
|
NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:74,443,872...74,479,839
|
|
G
|
Pecr
|
peroxisomal trans-2-enoyl-CoA reductase
|
multiple interactions
|
ISO
|
[lauroyl-coenzyme A co-treated with NADP] binds to PECR protein
|
CTD |
PMID:25526675 |
|
NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:73,897,880...73,926,511
|
|
|
G
|
Mlycd
|
malonyl-CoA decarboxylase
|
multiple interactions
|
ISO
|
PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A]
|
CTD |
PMID:14641110 |
|
NCBI chr19:64,356,582...64,372,447
Ensembl chr19:47,447,970...47,463,793
|
|
G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
multiple interactions
|
ISO
|
PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A]
|
CTD |
PMID:14641110 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
|
|
|
G
|
Echs1
|
enoyl-CoA hydratase, short chain 1
|
increases abundance
|
ISO
|
ECHS1 gene mutant form results in increased abundance of methacrylyl-coenzyme A
|
CTD |
PMID:25125611 |
|
NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:194,895,036...194,903,884
|
|
G
|
Hibch
|
3-hydroxyisobutyryl-CoA hydrolase
|
increases abundance
|
ISO
|
HIBCH gene mutant form results in increased abundance of methacrylyl-coenzyme A
|
CTD |
PMID:25125611 |
|
NCBI chr 9:56,082,082...56,161,796
Ensembl chr 9:48,590,099...48,669,824
|
|
|
G
|
Dbi
|
diazepam binding inhibitor
|
affects binding
|
ISO
|
S-tetradecanoyl-coenzyme A binds to DBI protein
|
CTD |
PMID:17044054 |
|
NCBI chr13:33,794,231...33,802,632
Ensembl chr13:31,206,988...31,268,693
|
|
G
|
Gsta1
|
glutathione S-transferase alpha 1
|
multiple interactions
|
ISO
|
S-tetradecanoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein
|
CTD |
PMID:10542059 |
|
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:23,703,477...23,720,121
|
|
G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
multiple interactions
|
ISO
|
S-tetradecanoyl-coenzyme A binds to and results in increased activity of PPARA protein
|
CTD |
PMID:11139385 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
|
|
|
G
|
Gsta1
|
glutathione S-transferase alpha 1
|
multiple interactions
|
ISO
|
oleoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein
|
CTD |
PMID:10542059 |
|
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:23,703,477...23,720,121
|
|
G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
multiple interactions
|
ISO
|
oleoyl-coenzyme A binds to and results in increased activity of PPARA protein
|
CTD |
PMID:11139385 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
|
|
G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
multiple interactions
|
ISO
|
oleoyl-coenzyme A binds to and results in increased activity of PPARG protein
|
CTD |
PMID:11139385 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468
|
|
|
G
|
Acox1
|
acyl-CoA oxidase 1
|
increases metabolic processing multiple interactions
|
ISO
|
ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A [ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide; benz(a)anthracene promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Dehydroepiandrosterone promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Tetrachlorodibenzodioxin promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]
|
CTD |
PMID:10497882 |
|
NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,406,197...101,431,232
|
|
G
|
Ces1d
|
carboxylesterase 1D
|
increases hydrolysis
|
EXP
|
CES1 protein results in increased hydrolysis of Palmitoyl Coenzyme A
|
CTD |
PMID:8611161 |
|
NCBI chr19:30,046,494...30,085,039
Ensembl chr19:13,796,623...13,912,035
|
|
G
|
Cpt1a
|
carnitine palmitoyltransferase 1A
|
multiple interactions
|
EXP
|
valproyl-coenzyme A inhibits the reaction [CPT1A protein results in increased metabolism of Palmitoyl Coenzyme A]
|
CTD |
PMID:19854160 |
|
NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055
|
|
G
|
Dgat1
|
diacylglycerol O-acyltransferase 1
|
multiple interactions
|
ISO
|
DGAT1 protein results in increased metabolism of [Palmitoyl Coenzyme A co-treated with Vitamin A]
|
CTD |
PMID:16214399 |
|
NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:108,218,524...108,234,299
|
|
G
|
Gsta1
|
glutathione S-transferase alpha 1
|
multiple interactions
|
ISO
|
Palmitoyl Coenzyme A binds to and results in decreased activity of GSTA1 protein
|
CTD |
PMID:10542059 |
|
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:23,703,477...23,720,121
|
|
G
|
Hnf4a
|
hepatocyte nuclear factor 4, alpha
|
decreases expression
|
ISO
|
Palmitoyl Coenzyme A results in decreased expression of HNF4A mRNA; Palmitoyl Coenzyme A results in decreased expression of HNF4A protein
|
CTD |
PMID:17992261 |
|
NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:152,186,787...152,248,320
|
|
G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
multiple interactions
|
ISO
|
Palmitoyl Coenzyme A binds to and results in increased activity of PPARA protein Acetylglucosamine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Atorvastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Atropine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Budesonide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Enalapril inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Fenofibrate promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; gamma-Aminobutyric Acid inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; gedunin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]; Pravastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Pyrazinamide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Saccharin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; salicylamide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Tolazoline inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Tolmetin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]
|
CTD |
PMID:11139385 PMID:18812576 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
|
|
G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
multiple interactions
|
ISO
|
Palmitoyl Coenzyme A binds to and results in increased activity of PPARG protein
|
CTD |
PMID:11139385 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468
|
|
G
|
Shbg
|
sex hormone binding globulin
|
decreases expression
|
ISO
|
Palmitoyl Coenzyme A results in decreased expression of SHBG mRNA; Palmitoyl Coenzyme A results in decreased expression of SHBG protein
|
CTD |
PMID:17992261 |
|
NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,332,941...54,351,057
|
|
|
G
|
Gsta1
|
glutathione S-transferase alpha 1
|
multiple interactions
|
ISO
|
stearoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein
|
CTD |
PMID:10542059 |
|
NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:23,703,477...23,720,121
|
|
G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
multiple interactions
|
ISO
|
stearoyl-coenzyme A binds to and results in increased activity of PPARA protein
|
CTD |
PMID:11139385 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
|
|
G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
multiple interactions
|
ISO
|
stearoyl-coenzyme A binds to and results in increased activity of PPARG protein
|
CTD |
PMID:11139385 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468
|
|
|
G
|
Acot4
|
acyl-CoA thioesterase 4
|
affects hydrolysis
|
ISO
|
ACOT4 protein affects the hydrolysis of succinyl-coenzyme A
|
CTD |
PMID:16141203 |
|
NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:103,668,753...103,673,917
|
|
|
G
|
Cxcl2
|
C-X-C motif chemokine ligand 2
|
multiple interactions
|
ISO
|
P2RY6 gene affects the reaction [Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of CXCL2 protein]]; Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of CXCL2 protein]
|
CTD |
PMID:18523137 |
|
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,181,062...17,183,075
|
|
G
|
Cysltr1
|
cysteinyl leukotriene receptor 1
|
multiple interactions
|
ISO
|
[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein; montelukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; montelukast inhibits the reaction [[Uridine Diphosphate metabolite results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein]; Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein; zafirlukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [[Uridine Diphosphate metabolite results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein]
|
CTD |
PMID:20083671 |
|
NCBI chr X:71,661,421...71,690,012
Ensembl chr X:71,663,821...71,690,121
|
|
G
|
Gpr17
|
G protein-coupled receptor 17
|
multiple interactions
|
ISO
|
cangrelor inhibits the reaction [Uridine Diphosphate results in increased activity of GPR17 protein]
|
CTD |
PMID:18974869 |
|
NCBI chr18:23,576,232...23,583,153
Ensembl chr18:23,577,242...23,582,966
|
|
G
|
H2ax
|
H2A.X variant histone
|
multiple interactions
|
ISO
|
Uridine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]
|
CTD |
PMID:32941855 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:44,671,786...44,673,239 Ensembl chr 4:44,671,786...44,673,239
|
|
G
|
Idh2
|
isocitrate dehydrogenase (NADP(+)) 2
|
increases abundance multiple interactions
|
ISO
|
IDH2 protein mutant form results in increased abundance of Uridine Diphosphate Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Uridine Diphosphate]
|
CTD |
PMID:27469509 |
|
NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025
|
|
G
|
Il6
|
interleukin 6
|
multiple interactions increases expression
|
ISO
|
MRS 2211 inhibits the reaction [Uridine Diphosphate results in increased expression of IL6 protein]; P2RY6 gene affects the reaction [Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
|
CTD |
PMID:18523137 PMID:24849676 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
|
|
G
|
Mapk1
|
mitogen activated protein kinase 1
|
increases phosphorylation multiple interactions
|
ISO
|
Uridine Diphosphate results in increased phosphorylation of MAPK1 protein P2RY6 gene mutant form inhibits the reaction [Uridine Diphosphate results in increased phosphorylation of MAPK1 protein]
|
CTD |
PMID:15034929 PMID:18523137 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
|
|
G
|
Mapk3
|
mitogen activated protein kinase 3
|
increases phosphorylation multiple interactions
|
ISO
|
Uridine Diphosphate results in increased phosphorylation of MAPK3 protein P2RY6 gene mutant form inhibits the reaction [Uridine Diphosphate results in increased phosphorylation of MAPK3 protein]
|
CTD |
PMID:15034929 PMID:18523137 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
|
|
G
|
P2ry6
|
pyrimidinergic receptor P2Y6
|
multiple interactions affects response to substance
|
ISO
|
P2RY6 gene affects the reaction [Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of CXCL2 protein]]; P2RY6 gene affects the reaction [Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; P2RY6 gene mutant form inhibits the reaction [Uridine Diphosphate results in increased phosphorylation of MAPK1 protein]; P2RY6 gene mutant form inhibits the reaction [Uridine Diphosphate results in increased phosphorylation of MAPK3 protein] P2RY6 gene affects the susceptibility to Uridine Diphosphate
|
CTD |
PMID:18523137 |
|
NCBI chr 1:164,707,188...164,742,689
Ensembl chr 1:155,295,111...155,330,808
|
|
G
|
Tp53bp1
|
tumor protein p53 binding protein 1
|
multiple interactions
|
ISO
|
Uridine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]
|
CTD |
PMID:32941855 |
|
NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
|
|
|
G
|
Gale
|
UDP-galactose-4-epimerase
|
affects binding
|
ISO
|
Uridine Diphosphate Galactose binds to GALE protein
|
CTD |
PMID:25526675 |
|
NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388
|
|
G
|
Gpr17
|
G protein-coupled receptor 17
|
increases activity
|
ISO
|
Uridine Diphosphate Galactose results in increased activity of GPR17 protein
|
CTD |
PMID:18974869 |
|
NCBI chr18:23,576,232...23,583,153
Ensembl chr18:23,577,242...23,582,966
|
|
G
|
Uxs1
|
UDP-glucuronate decarboxylase 1
|
multiple interactions
|
ISO
|
[Uridine Diphosphate Galactose co-treated with NAD] binds to UXS1 protein
|
CTD |
PMID:25526675 |
|
NCBI chr 9:653,740...731,121
Ensembl chr 9:653,659...756,334
|
|
|
G
|
Gale
|
UDP-galactose-4-epimerase
|
affects binding
|
ISO
|
Uridine Diphosphate Glucose binds to GALE protein
|
CTD |
PMID:25526675 |
|
NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388
|
|
G
|
Gpr17
|
G protein-coupled receptor 17
|
increases activity
|
ISO
|
Uridine Diphosphate Glucose results in increased activity of GPR17 protein
|
CTD |
PMID:18974869 |
|
NCBI chr18:23,576,232...23,583,153
Ensembl chr18:23,577,242...23,582,966
|
|
G
|
Uxs1
|
UDP-glucuronate decarboxylase 1
|
multiple interactions
|
ISO
|
[Uridine Diphosphate Glucose co-treated with NAD] binds to UXS1 protein
|
CTD |
PMID:25526675 |
|
NCBI chr 9:653,740...731,121
Ensembl chr 9:653,659...756,334
|
|
|
G
|
Abcb11
|
ATP binding cassette subfamily B member 11
|
multiple interactions
|
ISO
|
[NADP co-treated with Uridine Diphosphate Glucuronic Acid co-treated with Phosphoadenosine Phosphosulfate] promotes the reaction [[Enzymes and Coenzymes results in increased metabolism of diosbulbin B] inhibits the reaction [ABCB11 protein results in increased transport of Taurodeoxycholic Acid]]; [NADP co-treated with Uridine Diphosphate Glucuronic Acid co-treated with Phosphoadenosine Phosphosulfate] promotes the reaction [[Enzymes and Coenzymes results in increased metabolism of saikogenin A analog] inhibits the reaction [ABCB11 protein results in increased transport of Taurodeoxycholic Acid]]; [NADP co-treated with Uridine Diphosphate Glucuronic Acid co-treated with Phosphoadenosine Phosphosulfate] promotes the reaction [[Enzymes and Coenzymes results in increased metabolism of saikogenin A] inhibits the reaction [ABCB11 protein results in increased transport of Taurodeoxycholic Acid]]
|
CTD |
PMID:35101544 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:54,017,127...54,112,730
|
|
G
|
B3gat3
|
beta-1,3-glucuronyltransferase 3
|
affects binding multiple interactions
|
ISO
|
B3GAT3 protein binds to Uridine Diphosphate Glucuronic Acid Uridine Diphosphate Glucuronic Acid inhibits the reaction [Diacetyl results in decreased activity of B3GAT3 protein]
|
CTD |
PMID:11986319 |
|
NCBI chr 1:205,817,374...205,823,928
Ensembl chr 1:205,817,378...205,837,807
|
|
G
|
Gale
|
UDP-galactose-4-epimerase
|
affects binding
|
ISO
|
Uridine Diphosphate Glucuronic Acid binds to GALE protein
|
CTD |
PMID:25526675 |
|
NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388
|
|
G
|
Ppargc1a
|
PPARG coactivator 1 alpha
|
increases expression
|
ISO
|
Uridine Diphosphate Glucuronic Acid results in increased expression of PPARGC1A mRNA
|
CTD |
PMID:23056435 |
|
NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656
|
|
G
|
Ugt1a1
|
UDP glucuronosyltransferase family 1 member A1
|
multiple interactions
|
ISO
|
[Uridine Diphosphate Glucuronic Acid co-treated with UGT1A1 protein] results in increased glucuronidation of Labetalol
|
CTD |
PMID:18098064 |
|
NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:88,713,184...88,808,465
|
|
G
|
Ugt1a2
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UDP glucuronosyltransferase 1 family, polypeptide A2
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multiple interactions
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ISO
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[Uridine Diphosphate Glucuronic Acid co-treated with UGT1A3 protein] results in increased metabolism of Lithocholic Acid
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CTD |
PMID:36473578 |
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NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:88,713,184...88,808,465
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G
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Ugt2b7
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UDP glucuronosyltransferase family 2 member B7
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multiple interactions
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ISO
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[Uridine Diphosphate Glucuronic Acid co-treated with UGT2B7 protein] results in increased glucuronidation of Labetalol; [Uridine Diphosphate Glucuronic Acid co-treated with UGT2B7 protein] results in increased metabolism of hyodeoxycholic acid; Fluconazole inhibits the reaction [[Uridine Diphosphate Glucuronic Acid co-treated with UGT2B7 protein] results in increased glucuronidation of Labetalol]
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CTD |
PMID:18098064 PMID:36473578 |
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NCBI chr14:21,251,535...21,274,451
Ensembl chr14:20,896,682...20,919,604
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G
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Uxs1
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UDP-glucuronate decarboxylase 1
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multiple interactions
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ISO
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[Uridine Diphosphate Glucuronic Acid co-treated with NAD] binds to UXS1 protein
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CTD |
PMID:25526675 |
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NCBI chr 9:653,740...731,121
Ensembl chr 9:653,659...756,334
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G
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Gale
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UDP-galactose-4-epimerase
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affects binding
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ISO
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Uridine Diphosphate Galactose binds to GALE protein
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CTD |
PMID:25526675 |
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NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388
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G
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Gpr17
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G protein-coupled receptor 17
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increases activity
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ISO
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Uridine Diphosphate Galactose results in increased activity of GPR17 protein
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CTD |
PMID:18974869 |
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NCBI chr18:23,576,232...23,583,153
Ensembl chr18:23,577,242...23,582,966
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G
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Uxs1
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UDP-glucuronate decarboxylase 1
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multiple interactions
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ISO
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[Uridine Diphosphate Galactose co-treated with NAD] binds to UXS1 protein
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CTD |
PMID:25526675 |
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NCBI chr 9:653,740...731,121
Ensembl chr 9:653,659...756,334
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|
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G
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Gale
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UDP-galactose-4-epimerase
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affects binding
|
ISO
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Uridine Diphosphate Glucose binds to GALE protein
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CTD |
PMID:25526675 |
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NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388
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G
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Gpr17
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G protein-coupled receptor 17
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increases activity
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ISO
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Uridine Diphosphate Glucose results in increased activity of GPR17 protein
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CTD |
PMID:18974869 |
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NCBI chr18:23,576,232...23,583,153
Ensembl chr18:23,577,242...23,582,966
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G
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Uxs1
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UDP-glucuronate decarboxylase 1
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multiple interactions
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ISO
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[Uridine Diphosphate Glucose co-treated with NAD] binds to UXS1 protein
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CTD |
PMID:25526675 |
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NCBI chr 9:653,740...731,121
Ensembl chr 9:653,659...756,334
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G
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Gale
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UDP-galactose-4-epimerase
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affects binding
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ISO
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Uridine Diphosphate N-Acetylgalactosamine binds to GALE protein
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CTD |
PMID:25526675 |
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NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388
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G
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Idh2
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isocitrate dehydrogenase (NADP(+)) 2
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multiple interactions increases abundance
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ISO
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Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Uridine Diphosphate N-Acetylglucosamine]
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CTD |
PMID:27469509 |
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NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025
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