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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:UDP
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Accession:CHEBI:17659 term browser browse the term
Definition:A pyrimidine ribonucleoside 5'-diphosphate that has formula C9H14N2O12P2.
Synonyms:related_synonym: Formula=C9H14N2O12P2;   InChI=1S/C9H14N2O12P2/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1;   InChIKey=XCCTYIAWTASOJW-XVFCMESISA-N;   SMILES=O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O;   Uridine 5'-diphosphate;   Uridine diphosphate;   uridine 5'-(trihydrogen diphosphate)
 alt_id: CHEBI:13445;   CHEBI:27230;   CHEBI:46402;   CHEBI:9802
 xref: Beilstein:64707;   CAS:58-98-0;   DrugBank:DB03435;   KEGG:C00015;   KEGG:G10619;   KNApSAcK:C00007313
 xref_mesh: MESH:D014530
 xref: Wikipedia:Uridine_Diphosphate
 cyclic_relationship: is_conjugate_acid_of CHEBI:58223


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UDP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO P2RY6 gene affects the reaction [Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of CXCL2 protein]]; Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of CXCL2 protein] CTD PMID:18523137 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 multiple interactions ISO [Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein; montelukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; montelukast inhibits the reaction [[Uridine Diphosphate metabolite results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein]; Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein; zafirlukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [[Uridine Diphosphate metabolite results in increased activity of CYSLTR1 protein] which results in increased expression of CXCL8 protein] CTD PMID:20083671 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269
JBrowse link
G Gpr17 G protein-coupled receptor 17 multiple interactions ISO cangrelor inhibits the reaction [Uridine Diphosphate results in increased activity of GPR17 protein] CTD PMID:18974869 NCBI chr18:24,733,306...24,739,194
Ensembl chr18:24,734,330...24,735,349
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions
ISO IDH2 protein mutant form results in increased abundance of Uridine Diphosphate
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Uridine Diphosphate]
CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO MRS 2211 inhibits the reaction [Uridine Diphosphate results in increased expression of IL6 protein]; P2RY6 gene affects the reaction [Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:18523137 PMID:24849676 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO Uridine Diphosphate results in increased phosphorylation of MAPK1 protein
P2RY6 gene mutant form inhibits the reaction [Uridine Diphosphate results in increased phosphorylation of MAPK1 protein]
CTD PMID:15034929 PMID:18523137 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO Uridine Diphosphate results in increased phosphorylation of MAPK3 protein
P2RY6 gene mutant form inhibits the reaction [Uridine Diphosphate results in increased phosphorylation of MAPK3 protein]
CTD PMID:15034929 PMID:18523137 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 multiple interactions
affects response to substance
ISO P2RY6 gene affects the reaction [Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of CXCL2 protein]]; P2RY6 gene affects the reaction [Uridine Diphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; P2RY6 gene mutant form inhibits the reaction [Uridine Diphosphate results in increased phosphorylation of MAPK1 protein]; P2RY6 gene mutant form inhibits the reaction [Uridine Diphosphate results in increased phosphorylation of MAPK3 protein]
P2RY6 gene affects the susceptibility to Uridine Diphosphate
CTD PMID:18523137 NCBI chr 1:165,972,439...166,008,348
Ensembl chr 1:165,972,440...165,997,751
JBrowse link
UDP-alpha-D-galactose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gale UDP-galactose-4-epimerase affects binding ISO Uridine Diphosphate Galactose binds to GALE protein CTD PMID:25526675 NCBI chr 5:154,310,453...154,314,959
Ensembl chr 5:154,310,453...154,314,955
JBrowse link
G Gpr17 G protein-coupled receptor 17 increases activity ISO Uridine Diphosphate Galactose results in increased activity of GPR17 protein CTD PMID:18974869 NCBI chr18:24,733,306...24,739,194
Ensembl chr18:24,734,330...24,735,349
JBrowse link
G Uxs1 UDP-glucuronate decarboxylase 1 multiple interactions ISO [Uridine Diphosphate Galactose co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 NCBI chr 9:11,165,006...11,240,329
Ensembl chr 9:11,164,715...11,339,790
JBrowse link
UDP-alpha-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gale UDP-galactose-4-epimerase affects binding ISO Uridine Diphosphate Glucose binds to GALE protein CTD PMID:25526675 NCBI chr 5:154,310,453...154,314,959
Ensembl chr 5:154,310,453...154,314,955
JBrowse link
G Gpr17 G protein-coupled receptor 17 increases activity ISO Uridine Diphosphate Glucose results in increased activity of GPR17 protein CTD PMID:18974869 NCBI chr18:24,733,306...24,739,194
Ensembl chr18:24,734,330...24,735,349
JBrowse link
G Uxs1 UDP-glucuronate decarboxylase 1 multiple interactions ISO [Uridine Diphosphate Glucose co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 NCBI chr 9:11,165,006...11,240,329
Ensembl chr 9:11,164,715...11,339,790
JBrowse link
UDP-alpha-D-glucuronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3gat3 beta-1,3-glucuronyltransferase 3 affects binding
multiple interactions
ISO B3GAT3 protein binds to Uridine Diphosphate Glucuronic Acid
Uridine Diphosphate Glucuronic Acid inhibits the reaction [Diacetyl results in decreased activity of B3GAT3 protein]
CTD PMID:11986319 NCBI chr 1:225,120,061...225,126,579
Ensembl chr 1:225,120,061...225,126,579
JBrowse link
G Gale UDP-galactose-4-epimerase affects binding ISO Uridine Diphosphate Glucuronic Acid binds to GALE protein CTD PMID:25526675 NCBI chr 5:154,310,453...154,314,959
Ensembl chr 5:154,310,453...154,314,955
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Uridine Diphosphate Glucuronic Acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO [Uridine Diphosphate Glucuronic Acid co-treated with UGT1A1 protein] results in increased glucuronidation of Labetalol CTD PMID:18098064 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 multiple interactions ISO [Uridine Diphosphate Glucuronic Acid co-treated with UGT2B7 protein] results in increased glucuronidation of Labetalol; Fluconazole inhibits the reaction [[Uridine Diphosphate Glucuronic Acid co-treated with UGT2B7 protein] results in increased glucuronidation of Labetalol] CTD PMID:18098064 NCBI chr14:22,597,103...22,619,968 JBrowse link
G Uxs1 UDP-glucuronate decarboxylase 1 multiple interactions ISO [Uridine Diphosphate Glucuronic Acid co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 NCBI chr 9:11,165,006...11,240,329
Ensembl chr 9:11,164,715...11,339,790
JBrowse link
UDP-D-galactose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gale UDP-galactose-4-epimerase affects binding ISO Uridine Diphosphate Galactose binds to GALE protein CTD PMID:25526675 NCBI chr 5:154,310,453...154,314,959
Ensembl chr 5:154,310,453...154,314,955
JBrowse link
G Gpr17 G protein-coupled receptor 17 increases activity ISO Uridine Diphosphate Galactose results in increased activity of GPR17 protein CTD PMID:18974869 NCBI chr18:24,733,306...24,739,194
Ensembl chr18:24,734,330...24,735,349
JBrowse link
G Uxs1 UDP-glucuronate decarboxylase 1 multiple interactions ISO [Uridine Diphosphate Galactose co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 NCBI chr 9:11,165,006...11,240,329
Ensembl chr 9:11,164,715...11,339,790
JBrowse link
UDP-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gale UDP-galactose-4-epimerase affects binding ISO Uridine Diphosphate Glucose binds to GALE protein CTD PMID:25526675 NCBI chr 5:154,310,453...154,314,959
Ensembl chr 5:154,310,453...154,314,955
JBrowse link
G Gpr17 G protein-coupled receptor 17 increases activity ISO Uridine Diphosphate Glucose results in increased activity of GPR17 protein CTD PMID:18974869 NCBI chr18:24,733,306...24,739,194
Ensembl chr18:24,734,330...24,735,349
JBrowse link
G Uxs1 UDP-glucuronate decarboxylase 1 multiple interactions ISO [Uridine Diphosphate Glucose co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 NCBI chr 9:11,165,006...11,240,329
Ensembl chr 9:11,164,715...11,339,790
JBrowse link
UDP-N-acetyl-alpha-D-galactosamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gale UDP-galactose-4-epimerase affects binding ISO Uridine Diphosphate N-Acetylgalactosamine binds to GALE protein CTD PMID:25526675 NCBI chr 5:154,310,453...154,314,959
Ensembl chr 5:154,310,453...154,314,955
JBrowse link
UDP-N-acetyl-alpha-D-glucosamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Uridine Diphosphate N-Acetylglucosamine] CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link

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  CHEBI ontology 19841
    role 19792
      biological role 19792
        biochemical role 19328
          metabolite 19308
            prokaryotic metabolite 18409
              bacterial metabolite 18409
                Escherichia coli metabolite 18290
                  UDP 14
                    UDP-sugar + 8
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  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
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            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      chalcogen 19425
                        oxygen atom 19387
                          oxygen molecular entity 19387
                            hydroxides 19113
                              oxoacid 18243
                                pnictogen oxoacid 10293
                                  phosphorus oxoacid 9214
                                    phosphoric acids 7931
                                      phosphoric acid 7931
                                        phosphoric acid derivative 7612
                                          phosphate 7612
                                            organic phosphate 7611
                                              carbohydrate phosphate 1700
                                                phospho sugar 1627
                                                  aldose phosphate 1625
                                                    aldopentose phosphate 1619
                                                      ribose phosphate 1614
                                                        ribonucleotide 1575
                                                          ribonucleoside 5'-phosphate 591
                                                            ribonucleoside 5'-diphosphate 107
                                                              pyrimidine ribonucleoside 5'-diphosphate 19
                                                                UDP 14
                                                                  UDP-sugar + 8
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