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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:SP2509
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Accession:CHEBI:176335 term browser browse the term
Definition:3-(4-morpholinylsulfonyl)-benzoic acid (2E)-2-[1-(5-chloro-2-hydroxyphenyl)ethylidene]hydrazide
Synonyms:xref: CAS:1423715-09-6
 xref_mesh: MESH:C000594309
 xref: PMID:34031383



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SP2509 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression ISO SP2509 results in decreased expression of BUB1B mRNA CTD PMID:29581250 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G Casp3 caspase 3 increases activity ISO SP2509 results in increased activity of CASP3 protein CTD PMID:29581250 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO SP2509 results in decreased expression of CCNA2 mRNA CTD PMID:29581250 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Cenpf centromere protein F multiple interactions
decreases expression
ISO SP2509 inhibits the reaction [KDM1A protein binds to CENPF promoter]
SP2509 results in decreased expression of CENPF mRNA
CTD PMID:29581250 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Cenpk centromere protein K multiple interactions ISO SP2509 inhibits the reaction [KDM1A protein binds to CENPK promoter] CTD PMID:29581250 NCBI chr 2:35,360,132...35,421,372
Ensembl chr 2:35,360,132...35,385,706
JBrowse link
G Kdm1a lysine demethylase 1A decreases expression
multiple interactions
ISO SP2509 results in decreased expression of KDM1A protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SP2509 results in decreased stability of KDM1A protein]; SP2509 binds to and results in decreased stability of KDM1A protein; SP2509 inhibits the reaction [KDM1A protein binds to CENPF promoter]; SP2509 inhibits the reaction [KDM1A protein binds to CENPK promoter]; SP2509 inhibits the reaction [KDM1A protein binds to ZNF217 protein]
CTD PMID:29581250 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Stil STIL, centriolar assembly protein decreases expression ISO SP2509 results in decreased expression of STIL mRNA CTD PMID:29581250 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730
JBrowse link
G Tpx2 TPX2, microtubule nucleation factor decreases expression ISO SP2509 results in decreased expression of TPX2 mRNA CTD PMID:29581250 NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
JBrowse link
G Zfp217 zinc finger protein 217 multiple interactions ISO SP2509 inhibits the reaction [KDM1A protein binds to ZNF217 protein] CTD PMID:29581250 NCBI chr 3:158,890,464...158,931,148
Ensembl chr 3:158,892,265...158,913,040
JBrowse link
G Zwilch zwilch kinetochore protein decreases expression ISO SP2509 results in decreased expression of ZWILCH mRNA CTD PMID:29581250 NCBI chr 8:64,638,401...64,670,911
Ensembl chr 8:64,637,672...64,675,916
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19823
    chemical entity 19823
      atom 19821
        nonmetal atom 19709
          carbon atom 19633
            organic molecular entity 19633
              SP2509 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19823
    subatomic particle 19821
      composite particle 19821
        hadron 19821
          baryon 19821
            nucleon 19821
              atomic nucleus 19821
                atom 19821
                  main group element atom 19720
                    p-block element atom 19720
                      carbon group element atom 19643
                        carbon atom 19633
                          organic molecular entity 19633
                            SP2509 10
paths to the root