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ONTOLOGY REPORT - ANNOTATIONS


Term:kanamycin A
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Accession:CHEBI:17630 term browser browse the term
Definition:A kanamycin that has formula C18H36N4O11.
Synonyms:exact_synonym: (1S,2R,3R,4S,6R)-4,6-diamino-3-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside
 related_synonym: 4,6-diamino-2-hydroxy-1,3-cyclohexane 3,6'diamino-3,6'-dideoxydi-alpha-D-glucoside;   4,6-diamino-2-hydroxy-1,3-cyclohexylene 3,6'-diamino-3,6'-dideoxydi-D-glucopyranoside;   Formula=C18H36N4O11;   InChI=1S/C18H36N4O11/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17/h4-18,23-29H,1-3,19-22H2/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-/m1/s1;   InChIKey=SBUJHOSQTJFQJX-NOAMYHISSA-N;   O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->4))-2-deoxy-D-streptamine;   SMILES=NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
 alt_id: CHEBI:14487;   CHEBI:24945;   CHEBI:24947;   CHEBI:43482;   CHEBI:6106
 xref: Beilstein:61647;   CAS:59-01-8;   DrugBank:DB01172;   Drug_Central:1519;   Gmelin:2044856;   KEGG:C01822;   LINCS:LSM-5261
 xref_mesh: MESH:D007612
 xref: PDBeChem:KAN;   PMID:22907688;   PMID:24336356;   PMID:24566637;   VSDB:1921;   Wikipedia:Kanamycin
 cyclic_relationship: is_conjugate_base_of CHEBI:58214


show annotations for term's descendants       view all columns           Sort by:
 
kanamycin A term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:6480464
G Diaph1 diaphanous-related formin 1 JBrowse link 18 30,972,907 31,071,371 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:6480464
G Ncf2 neutrophil cytosolic factor 2 JBrowse link 13 70,226,441 70,259,019 RGD:6480464
G Prdx3 peroxiredoxin 3 JBrowse link 1 282,238,774 282,251,193 RGD:6480464
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:6480464
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:6480464
G Slc1a3 solute carrier family 1 member 3 JBrowse link 2 57,860,881 57,935,363 RGD:6480464
amikacin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc3 ATP binding cassette subfamily C member 3 JBrowse link 10 82,047,308 82,116,928 RGD:6480464
G Abcc4 ATP binding cassette subfamily C member 4 JBrowse link 15 103,695,415 103,927,980 RGD:6480464
G Casr calcium-sensing receptor JBrowse link 11 67,188,204 67,262,261 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Pgd phosphogluconate dehydrogenase JBrowse link 5 165,966,128 165,982,327 RGD:6480464
G Tyr tyrosinase JBrowse link 1 151,012,598 151,106,802 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19717
      biological role 19716
        antimicrobial agent 17260
          carbohydrate-containing antibiotic 2552
            aminoglycoside antibiotic 2534
              kanamycins 24
                kanamycin A 15
                  2'-oxokanamycin 0
                  3'',6'-di-N-acetylkanamycin A 0
                  4'-adenylkanamycin A 0
                  6''-O-carbamoylkanamycin A 0
                  amikacin 6
                  kanamycin 0
                  kanamycin A 3'-phosphate 0
                  kanamycin A sulfate 0
                  kanamycin D + 0
                  kanamycin X + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    p-block element atom 19655
                      carbon group element atom 19548
                        carbon atom 19537
                          organic molecular entity 19537
                            heteroorganic entity 19129
                              organochalcogen compound 18828
                                organooxygen compound 18747
                                  carbohydrates and carbohydrate derivatives 12146
                                    carbohydrate 12146
                                      carbohydrate derivative 11770
                                        glycosyl compound 10806
                                          glycoside 9153
                                            aminoglycoside 8361
                                              aminoglycoside antibiotic 2534
                                                kanamycins 24
                                                  kanamycin A 15
                                                    2'-oxokanamycin 0
                                                    3'',6'-di-N-acetylkanamycin A 0
                                                    4'-adenylkanamycin A 0
                                                    6''-O-carbamoylkanamycin A 0
                                                    amikacin 6
                                                    kanamycin 0
                                                    kanamycin A 3'-phosphate 0
                                                    kanamycin A sulfate 0
                                                    kanamycin D + 0
                                                    kanamycin X + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.