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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dUMP
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Accession:CHEBI:17622 term browser browse the term
Definition:A pyrimidine 2'-deoxyribonucleoside 5'-monophosphate having uracil as the nucleobase.
Synonyms:exact_synonym: 2'-deoxy-5'-uridylic acid
 related_synonym: 2'-Deoxyuridine 5'-phosphate;   2'-deoxyuridine 5'-monophosphate;   Deoxyuridine 5'-phosphate;   Deoxyuridine monophosphate;   Deoxyuridylic acid;   Formula=C9H13N2O8P;   InChI=1S/C9H13N2O8P/c12-5-3-8(11-2-1-7(13)10-9(11)14)19-6(5)4-18-20(15,16)17/h1-2,5-6,8,12H,3-4H2,(H,10,13,14)(H2,15,16,17)/t5-,6+,8+/m0/s1;   InChIKey=JSRLJPSBLDHEIO-SHYZEUOFSA-N;   SMILES=O[C@H]1C[C@@H](O[C@@H]1COP(O)(O)=O)n1ccc(=O)[nH]c1=O;   deoxyuridylate
 alt_id: CHEBI:10532;   CHEBI:14094;   CHEBI:19263;   CHEBI:42245;   CHEBI:46286;   CHEBI:46288;   CHEBI:47722
 xref: CAS:964-26-1;   DrugBank:DB03800;   HMDB:HMDB0001409;   KEGG:C00365;   KNApSAcK:C00019282
 xref_mesh: MESH:C007267
 xref: MetaCyc:DUMP;   PDBeChem:DU;   PDBeChem:UMP;   PMID:22770225;   PMID:24147825;   Reaxys:42143;   Wikipedia:Deoxyuridine_monophosphate
 cyclic_relationship: is_conjugate_acid_of CHEBI:246422



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dUMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc5 ATP binding cassette subfamily C member 5 increases export ISO ABCC5 protein results in increased export of 2'-deoxyuridylic acid CTD PMID:15897250 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
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G Tyms thymidylate synthetase multiple interactions ISO [Fluorouracil results in decreased activity of TYMS protein] which results in increased abundance of 2'-deoxyuridylic acid CTD PMID:29258758 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19904
    role 19880
      biological role 19878
        biochemical role 19576
          metabolite 19562
            dUMP 2
              2'-deoxy-5-(4,5-dihydroxypentyl)uridine 5'-monophosphate 0
              5,6-dihydroxy-2'-deoxyuridine 5'-monophosphate 0
              5-carboxy-2'-deoxyuridine 5'-monophosphate 0
              dUMP 3'-end residue 0
              dUMP 5'-end residue 0
              dUMP residue + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19904
    subatomic particle 19902
      composite particle 19902
        hadron 19902
          baryon 19902
            nucleon 19902
              atomic nucleus 19902
                atom 19902
                  main group element atom 19852
                    p-block element atom 19852
                      chalcogen 19597
                        oxygen atom 19571
                          oxygen molecular entity 19571
                            hydroxides 19375
                              oxoacid 18772
                                pnictogen oxoacid 13194
                                  phosphorus oxoacid 12436
                                    phosphoric acids 11432
                                      phosphoric acid 11432
                                        phosphoric acid derivative 11240
                                          phosphate 11239
                                            organic phosphate 11239
                                              carbohydrate phosphate 1855
                                                phospho sugar 1700
                                                  aldose phosphate 1697
                                                    aldopentose phosphate 1689
                                                      deoxyaldopentose phosphate 9
                                                        2-deoxyribose phosphate 9
                                                          2'-deoxyribonucleotide 8
                                                            2'-deoxyribonucleoside 5'-phosphate 8
                                                              2'-deoxyribonucleoside 5'-monophosphate 3
                                                                pyrimidine 2'-deoxyribonucleoside 5'-monophosphate 3
                                                                  dUMP 2
                                                                    2'-deoxy-5-(4,5-dihydroxypentyl)uridine 5'-monophosphate 0
                                                                    5,6-dihydroxy-2'-deoxyuridine 5'-monophosphate 0
                                                                    5-carboxy-2'-deoxyuridine 5'-monophosphate 0
                                                                    dUMP 3'-end residue 0
                                                                    dUMP 5'-end residue 0
                                                                    dUMP residue + 0
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