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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dUMP
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Accession:CHEBI:17622 term browser browse the term
Definition:A pyrimidine 2'-deoxyribonucleoside 5'-monophosphate having uracil as the nucleobase.
Synonyms:exact_synonym: 2'-deoxy-5'-uridylic acid
 related_synonym: 2'-Deoxyuridine 5'-phosphate;   2'-deoxyuridine 5'-monophosphate;   Deoxyuridine 5'-phosphate;   Deoxyuridine monophosphate;   Deoxyuridylic acid;   Formula=C9H13N2O8P;   InChI=1S/C9H13N2O8P/c12-5-3-8(11-2-1-7(13)10-9(11)14)19-6(5)4-18-20(15,16)17/h1-2,5-6,8,12H,3-4H2,(H,10,13,14)(H2,15,16,17)/t5-,6+,8+/m0/s1;   InChIKey=JSRLJPSBLDHEIO-SHYZEUOFSA-N;   SMILES=O[C@H]1C[C@@H](O[C@@H]1COP(O)(O)=O)n1ccc(=O)[nH]c1=O;   deoxyuridylate
 alt_id: CHEBI:10532;   CHEBI:14094;   CHEBI:19263;   CHEBI:42245;   CHEBI:46286;   CHEBI:46288;   CHEBI:47722
 xref: CAS:964-26-1;   DrugBank:DB03800;   HMDB:HMDB0001409;   KEGG:C00365;   KNApSAcK:C00019282
 xref_mesh: MESH:C007267
 xref: MetaCyc:DUMP;   PDBeChem:DU;   PDBeChem:UMP;   PMID:22770225;   PMID:24147825;   Reaxys:42143;   Wikipedia:Deoxyuridine_monophosphate
 cyclic_relationship: is_conjugate_acid_of CHEBI:246422


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dUMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc5 ATP binding cassette subfamily C member 5 increases export ISO ABCC5 protein results in increased export of 2'-deoxyuridylic acid CTD PMID:15897250 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
G Tyms thymidylate synthetase multiple interactions ISO [Fluorouracil results in decreased activity of TYMS protein] which results in increased abundance of 2'-deoxyuridylic acid CTD PMID:29258758 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      biological role 19785
        biochemical role 19496
          metabolite 19484
            dUMP 2
              2'-deoxy-5-(4,5-dihydroxypentyl)uridine 5'-monophosphate 0
              5,6-dihydroxy-2'-deoxyuridine 5'-monophosphate 0
              5-carboxy-2'-deoxyuridine 5'-monophosphate 0
              dUMP 3'-end residue 0
              dUMP 5'-end residue 0
              dUMP residue + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      chalcogen 19515
                        oxygen atom 19520
                          oxygen molecular entity 19490
                            hydroxides 19300
                              oxoacid 18725
                                pnictogen oxoacid 13221
                                  phosphorus oxoacid 12413
                                    phosphoric acids 11427
                                      phosphoric acid 11417
                                        phosphoric acid derivative 11226
                                          phosphate 11225
                                            organic phosphate 11225
                                              carbohydrate phosphate 1855
                                                phospho sugar 1702
                                                  aldose phosphate 1699
                                                    aldopentose phosphate 1691
                                                      deoxyaldopentose phosphate 9
                                                        2-deoxyribose phosphate 9
                                                          2'-deoxyribonucleotide 8
                                                            2'-deoxyribonucleoside 5'-phosphate 8
                                                              2'-deoxyribonucleoside 5'-monophosphate 3
                                                                pyrimidine 2'-deoxyribonucleoside 5'-monophosphate 3
                                                                  dUMP 2
                                                                    2'-deoxy-5-(4,5-dihydroxypentyl)uridine 5'-monophosphate 0
                                                                    5,6-dihydroxy-2'-deoxyuridine 5'-monophosphate 0
                                                                    5-carboxy-2'-deoxyuridine 5'-monophosphate 0
                                                                    dUMP 3'-end residue 0
                                                                    dUMP 5'-end residue 0
                                                                    dUMP residue + 0
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