Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ferulic acid
go back to main search page
Accession:CHEBI:17620 term browser browse the term
Definition:A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring.
Synonyms:exact_synonym: (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
 related_synonym: (E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid;   (E)-4-Hydroxy-3-methoxycinnamic acid;   (E)-Ferulic acid;   3-(4-Hydroxy-3-methoxyphenyl)propenoic acid;   3-methoxy-4-hydroxy-trans-cinnamic acid;   4-hydroxy-3-methoxycinnamic acid;   Formula=C10H10O4;   InChI=1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+;   InChIKey=KSEBMYQBYZTDHS-HWKANZROSA-N;   SMILES=COc1cc(\\C=C\\C(O)=O)ccc1O;   trans-4-Hydroxy-3-methoxycinnamic acid;   trans-Ferulic acid
 alt_id: CHEBI:14260;   CHEBI:24030;   CHEBI:42445;   CHEBI:5046
 xref: CAS:1135-24-6;   CAS:537-98-4;   HMDB:HMDB0000954;   KEGG:C01494;   KNApSAcK:C00002743
 xref_mesh: MESH:C004999
 xref: MetaCyc:FERULIC-ACID;   PDBeChem:FER;   PMID:11041377;   PMID:11982438;   PMID:12529986;   PMID:15162367;   PMID:15309442;   PMID:16011737;   PMID:16185284;   PMID:18582080;   PMID:18651237;   PMID:18707110;   PMID:18795822;   PMID:19594750;   PMID:8821508;   Reaxys:1570363;   Wikipedia:Ferulic_Acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:29749


show annotations for term's descendants           Sort by:
ferulic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO ferulic acid inhibits the reaction [lead acetate results in increased activity of ACHE protein] CTD PMID:25322819 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728 		JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions EXP ferulic acid inhibits the reaction [Silicon Dioxide results in increased expression of ACTA2 protein] CTD PMID:33428986 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions ISO ferulic acid inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of AKT1 protein]; MIR17 mRNA affects the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of AKT1 protein]]; PTEN protein inhibits the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of AKT1 protein]] CTD PMID:35110471 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Alad aminolevulinate, delta-, dehydratase multiple interactions ISO ferulic acid inhibits the reaction [lead acetate results in decreased activity of ALAD protein] CTD PMID:25322819 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155 		JBrowse link
G Alb albumin multiple interactions EXP ferulic acid inhibits the reaction [Silicon Dioxide results in increased expression of ALB protein]; ferulic acid inhibits the reaction [tyloxapol results in decreased expression of ALB mRNA] CTD PMID:33428986 PMID:37076581 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Apob apolipoprotein B decreases expression EXP ferulic acid results in decreased expression of APOB protein CTD PMID:20573577 NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835 		JBrowse link
G Bace1 beta-site APP cleaving enzyme 1 multiple interactions ISO ferulic acid inhibits the reaction [Copper results in increased expression of BACE1 mRNA] CTD PMID:18583042 NCBI chr 9:45,749,878...45,775,694
Ensembl chr 9:45,749,878...45,775,697 		JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein]; ferulic acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; MIR17 mRNA affects the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein]]; PTEN protein inhibits the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein]] CTD PMID:31029786 PMID:35110471 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO ferulic acid promotes the reaction [lead acetate results in increased activity of BCHE protein] CTD PMID:25322819 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO ferulic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]; MIR17 mRNA affects the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]]; PTEN protein inhibits the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]] CTD PMID:35110471 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G C3 complement component 3 multiple interactions EXP ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of C3 protein] CTD PMID:33140555 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO ferulic acid analog inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; ferulic acid inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]; MIR17 mRNA affects the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]]; PTEN protein inhibits the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]] CTD PMID:31029786 PMID:35110471 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Cat catalase increases activity
multiple interactions		 EXP
ISO		 ferulic acid results in increased activity of CAT protein
ferulic acid inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
ferulic acid inhibits the reaction [[Fatty Acids, Unsaturated co-treated with Ethanol] results in decreased activity of CAT protein]; ferulic acid inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased activity of CAT protein]; ferulic acid inhibits the reaction [Ethanol results in decreased activity of CAT protein]; ferulic acid inhibits the reaction [Fatty Acids, Unsaturated results in decreased activity of CAT protein]; ferulic acid inhibits the reaction [Thioacetamide results in decreased activity of CAT protein]		 CTD PMID:15381826 PMID:20573577 PMID:31584213 PMID:32278740 PMID:37393015 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein] CTD PMID:33140555 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions EXP ferulic acid inhibits the reaction [Silicon Dioxide results in increased expression of CTGF protein] CTD PMID:33428986 NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO ferulic acid results in decreased expression of CCND1 protein CTD PMID:15363954 PMID:15486966 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Cdh1 cadherin 1 multiple interactions EXP ferulic acid inhibits the reaction [Silicon Dioxide results in decreased expression of CDH1 protein] CTD PMID:33428986 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression ISO ferulic acid results in increased expression of CDKN1A protein CTD PMID:15363954 PMID:15486966 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Col1a2 collagen, type I, alpha 2 multiple interactions EXP ferulic acid inhibits the reaction [Silicon Dioxide results in increased expression of COL1A2 protein] CTD PMID:33428986 NCBI chr 6:4,505,618...4,541,543
Ensembl chr 6:4,504,814...4,541,544 		JBrowse link
G Ctsd cathepsin D multiple interactions ISO [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:17045618 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions ISO [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with ferulic acid] inhibits the reaction [[Ozone co-treated with Oxygen] results in increased expression of CXCL8 mRNA] CTD PMID:26270818 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO ferulic acid results in decreased activity of CYP1A1 protein CTD PMID:15841493 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO ferulic acid results in decreased activity of CYP1A2 protein CTD PMID:15841493 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Des desmin multiple interactions ISO ferulic acid inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of DES protein] CTD PMID:31584213 NCBI chr 1:75,336,936...75,345,223
Ensembl chr 1:75,336,973...75,345,223 		JBrowse link
G Dhfr dihydrofolate reductase decreases activity ISO ferulic acid results in decreased activity of DHFR protein CTD PMID:25418905 NCBI chr13:92,491,291...92,525,561
Ensembl chr13:92,491,234...92,525,561 		JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO ferulic acid inhibits the reaction [Streptozocin results in increased expression of DNM1L protein] CTD PMID:31029786 NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823 		JBrowse link
G Fasn fatty acid synthase decreases expression EXP ferulic acid results in decreased expression of FASN mRNA CTD PMID:21870829 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373 		JBrowse link
G Fdx1 ferredoxin 1 multiple interactions EXP ferulic acid analog promotes the reaction [Colforsin results in increased expression of FDX1 mRNA] CTD PMID:36279966 NCBI chr 9:51,854,323...51,874,902
Ensembl chr 9:51,854,606...51,874,856 		JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked decreases activity ISO ferulic acid results in decreased activity of G6PD protein CTD PMID:25130191 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800 		JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions ISO [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of GAL protein] CTD PMID:17045618 NCBI chr19:3,459,915...3,464,544
Ensembl chr19:3,459,915...3,464,544 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions EXP ferulic acid inhibits the reaction [sodium arsenite results in increased activity of GPT protein] CTD PMID:37393015 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Gsr glutathione reductase increases activity
multiple interactions		 EXP
ISO		 ferulic acid results in increased activity of GSR protein
ferulic acid inhibits the reaction [lead acetate results in increased activity of GSR protein]		 CTD PMID:20573577 PMID:25322819 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191 		JBrowse link
G Gusb glucuronidase, beta multiple interactions ISO [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of GUSB protein] CTD PMID:17045618 NCBI chr 5:130,011,278...130,031,890
Ensembl chr 5:130,017,852...130,031,890 		JBrowse link
G Hlcs holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) decreases activity ISO ferulic acid results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr16:93,930,054...94,116,098
Ensembl chr16:93,929,741...94,114,430 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase decreases expression EXP ferulic acid results in decreased expression of HMGCR mRNA CTD PMID:21870829 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444 		JBrowse link
G Il11 interleukin 11 multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in decreased expression of IL11 mRNA] CTD PMID:31054998 NCBI chr 7:4,775,372...4,785,877
Ensembl chr 7:4,775,372...4,785,858 		JBrowse link
G Il11ra1 interleukin 11 receptor subunit alpha 1 multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in decreased expression of IL11RA1 mRNA] CTD PMID:31054998 NCBI chr 4:41,760,443...41,769,473
Ensembl chr 4:41,699,989...41,769,474 		JBrowse link
G Il11ra2 interleukin 11 receptor subunit alpha 2 multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in decreased expression of IL11RA2 mRNA] CTD PMID:31054998 NCBI chr 4:42,656,001...42,665,744
Ensembl chr 4:42,656,001...42,665,763 		JBrowse link
G Il12b interleukin 12b multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL12B mRNA] CTD PMID:31054998 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860 		JBrowse link
G Il13ra1 interleukin 13 receptor, alpha 1 multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL13RA1 mRNA] CTD PMID:31054998 NCBI chr  X:35,375,761...35,434,915
Ensembl chr  X:35,375,763...35,434,912 		JBrowse link
G Il17a interleukin 17A multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL17A mRNA]; ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL17A protein] CTD PMID:31054998 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720 		JBrowse link
G Il17b interleukin 17B multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in decreased expression of IL17B mRNA] CTD PMID:31054998 NCBI chr18:61,821,006...61,825,609
Ensembl chr18:61,817,958...61,825,609 		JBrowse link
G Il17rb interleukin 17 receptor B multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in decreased expression of IL17RB mRNA] CTD PMID:31054998 NCBI chr14:29,718,125...29,730,853
Ensembl chr14:29,718,092...29,730,853 		JBrowse link
G Il18 interleukin 18 multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL18 mRNA] CTD PMID:31054998 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il18rap interleukin 18 receptor accessory protein multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL18RAP mRNA] CTD PMID:31054998 NCBI chr 1:40,554,548...40,590,867
Ensembl chr 1:40,554,522...40,590,865 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL1A mRNA] CTD PMID:31054998 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL1B mRNA]; ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL1B protein]; ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; ferulic acid inhibits the reaction [Silicon Dioxide results in increased expression of IL1B protein] CTD PMID:31054998 PMID:33140555 PMID:33428986 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1f10 interleukin 1 family, member 10 multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in decreased expression of IL1F10 mRNA] CTD PMID:31054998 NCBI chr 2:24,177,095...24,184,236
Ensembl chr 2:24,181,208...24,183,832 		JBrowse link
G Il20 interleukin 20 multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL20 mRNA] CTD PMID:31054998 NCBI chr 1:130,834,722...130,839,033
Ensembl chr 1:130,834,722...130,839,188 		JBrowse link
G Il20rb interleukin 20 receptor beta multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL20RB mRNA] CTD PMID:31054998 NCBI chr 9:100,339,772...100,368,526
Ensembl chr 9:100,339,772...100,368,841 		JBrowse link
G Il22ra1 interleukin 22 receptor, alpha 1 multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL22RA1 mRNA] CTD PMID:31054998 NCBI chr 4:135,455,470...135,482,694
Ensembl chr 4:135,455,483...135,479,451 		JBrowse link
G Il23a interleukin 23, alpha subunit p19 multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL23A mRNA]; ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL23A protein] CTD PMID:31054998 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621 		JBrowse link
G Il27 interleukin 27 multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL27 mRNA] CTD PMID:31054998 NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113 		JBrowse link
G Il33 interleukin 33 multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL33 mRNA] CTD PMID:31054998 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118 		JBrowse link
G Il36a interleukin 36A multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL36A mRNA] CTD PMID:31054998 NCBI chr 2:24,105,429...24,115,713
Ensembl chr 2:24,105,430...24,115,714 		JBrowse link
G Il36b interleukin 36B multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL36B mRNA] CTD PMID:31054998 NCBI chr 2:24,043,184...24,050,115
Ensembl chr 2:24,043,173...24,050,531 		JBrowse link
G Il36g interleukin 36G multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL36G mRNA] CTD PMID:31054998 NCBI chr 2:24,076,488...24,083,579
Ensembl chr 2:24,076,488...24,083,580 		JBrowse link
G Il36rn interleukin 36 receptor antagonist multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL36RN mRNA] CTD PMID:31054998 NCBI chr 2:24,166,966...24,172,444
Ensembl chr 2:24,166,966...24,173,438 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions		 EXP ferulic acid results in increased expression of IL6 mRNA
ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; ferulic acid inhibits the reaction [Silicon Dioxide results in increased expression of IL6 protein]; ferulic acid inhibits the reaction [tyloxapol results in increased expression of IL6 mRNA]		 CTD PMID:21870829 PMID:33140555 PMID:33428986 PMID:37076581 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Il7 interleukin 7 multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL7 mRNA] CTD PMID:31054998 NCBI chr 3:7,637,088...7,678,820
Ensembl chr 3:7,635,054...7,678,820 		JBrowse link
G Il7r interleukin 7 receptor multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL7R mRNA] CTD PMID:31054998 NCBI chr15:9,505,880...9,530,270
Ensembl chr15:9,505,874...9,530,262 		JBrowse link
G Il9r interleukin 9 receptor multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in decreased expression of IL9R mRNA] CTD PMID:31054998 NCBI chr11:32,137,544...32,155,283
Ensembl chr11:32,137,541...32,150,279 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IRAK2 mRNA] CTD PMID:31054998 NCBI chr 6:113,615,428...113,671,987
Ensembl chr 6:113,615,428...113,671,987 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 multiple interactions EXP ferulic acid inhibits the reaction [Imiquimod results in increased expression of IRAK3 mRNA] CTD PMID:31054998 NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035 		JBrowse link
G Jun jun proto-oncogene multiple interactions EXP ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of and results in increased localization of JUN protein] CTD PMID:21291945 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459 		JBrowse link
G Ldha lactate dehydrogenase A multiple interactions ISO [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with ferulic acid] inhibits the reaction [[Ozone co-treated with Oxygen] results in increased secretion of LDHA protein] CTD PMID:26270818 NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 decreases activity
multiple interactions		 ISO ferulic acid results in decreased activity of MAPK1 protein
[resveratrol co-treated with Phytic Acid co-treated with ferulic acid co-treated with Quercetin] results in increased phosphorylation of MAPK1 protein		 CTD PMID:15363954 PMID:15486966 PMID:21203465 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 decreases activity
multiple interactions		 ISO ferulic acid results in decreased activity of MAPK3 protein
[resveratrol co-treated with Phytic Acid co-treated with ferulic acid co-treated with Quercetin] results in increased phosphorylation of MAPK3 protein		 CTD PMID:15363954 PMID:15486966 PMID:21203465 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 decreases activity
multiple interactions		 ISO
EXP		 ferulic acid results in decreased activity of MAPK8 protein
ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK8 protein]		 CTD PMID:15363954 PMID:21291945 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO ferulic acid inhibits the reaction [Streptozocin results in decreased expression of MFN2 protein] CTD PMID:31029786 NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161 		JBrowse link
G Mir101a microRNA 101a multiple interactions ISO [resveratrol co-treated with Phytic Acid co-treated with ferulic acid co-treated with Quercetin] results in increased expression of MIR101A mRNA CTD PMID:21203465 NCBI chr 4:101,204,142...101,204,224
Ensembl chr 4:101,204,142...101,204,224 		JBrowse link
G Mir10a microRNA 10a multiple interactions ISO [resveratrol co-treated with Phytic Acid co-treated with ferulic acid co-treated with Quercetin] results in increased expression of MIR10A mRNA CTD PMID:21203465 NCBI chr11:96,207,991...96,208,100
Ensembl chr11:96,207,991...96,208,100 		JBrowse link
G Mir17 microRNA 17 multiple interactions ISO ferulic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of MIR17 mRNA]; MIR17 mRNA affects the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]]; MIR17 mRNA affects the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of AKT1 protein]]; MIR17 mRNA affects the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]]; MIR17 mRNA affects the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein]]; MIR17 mRNA affects the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTEN protein]] CTD PMID:35110471 NCBI chr14:115,281,103...115,281,186
Ensembl chr14:115,281,103...115,281,186 		JBrowse link
G Mir181c microRNA 181c multiple interactions ISO [Resveratrol co-treated with Phytic Acid co-treated with ferulic acid co-treated with Quercetin] results in increased expression of MIR181C mRNA CTD PMID:21203465 NCBI chr 8:84,905,502...84,905,590
Ensembl chr 8:84,905,502...84,905,590 		JBrowse link
G Mir200a microRNA 200a multiple interactions ISO ferulic acid inhibits the reaction [Thioacetamide results in decreased expression of MIR200A mRNA] CTD PMID:32278740 NCBI chr 4:156,139,353...156,139,442
Ensembl chr 4:156,139,353...156,139,442 		JBrowse link
G Mir20b microRNA 20b multiple interactions ISO [Resveratrol co-treated with Phytic Acid co-treated with ferulic acid co-treated with Quercetin] results in decreased expression of MIR20B mRNA CTD PMID:21203465 NCBI chr  X:51,830,990...51,831,069
Ensembl chr  X:51,830,990...51,831,069 		JBrowse link
G Mir214 microRNA 214 multiple interactions ISO [Resveratrol co-treated with Phytic Acid co-treated with ferulic acid co-treated with Quercetin] results in increased expression of MIR214 mRNA CTD PMID:21203465 NCBI chr 1:162,050,937...162,051,046
Ensembl chr 1:162,050,937...162,051,046 		JBrowse link
G Mir21a microRNA 21a multiple interactions
increases expression		 ISO [Resveratrol co-treated with Phytic Acid co-treated with ferulic acid co-treated with Quercetin] results in increased expression of MIR21 mRNA; ferulic acid inhibits the reaction [Thioacetamide results in increased expression of MIR21 mRNA]
ferulic acid results in increased expression of MIR21 mRNA		 CTD PMID:21203465 PMID:32278740 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984 		JBrowse link
G Mir25 microRNA 25 multiple interactions ISO [resveratrol co-treated with Phytic Acid co-treated with ferulic acid co-treated with Quercetin] results in increased expression of MIR25 mRNA CTD PMID:21203465 NCBI chr 5:138,163,583...138,163,666
Ensembl chr 5:138,163,583...138,163,666 		JBrowse link
G Mir27b microRNA 27b multiple interactions ISO [resveratrol co-treated with Phytic Acid co-treated with ferulic acid co-treated with Quercetin] results in decreased expression of MIR27B mRNA CTD PMID:21203465 NCBI chr13:63,448,526...63,448,598
Ensembl chr13:63,448,526...63,448,598 		JBrowse link
G Mir30a microRNA 30a multiple interactions ISO ferulic acid inhibits the reaction [Thioacetamide results in decreased expression of MIR30A mRNA] CTD PMID:32278740 NCBI chr 1:23,311,350...23,311,420
Ensembl chr 1:23,311,350...23,311,420 		JBrowse link
G Mir324 microRNA 324 multiple interactions ISO [Resveratrol co-treated with Phytic Acid co-treated with ferulic acid co-treated with Quercetin] results in increased expression of MIR324 mRNA CTD PMID:21203465 NCBI chr11:69,902,869...69,902,957
Ensembl chr11:69,902,869...69,902,957 		JBrowse link
G Mir339 microRNA 339 multiple interactions ISO [Resveratrol co-treated with Phytic Acid co-treated with ferulic acid co-treated with Quercetin] results in increased expression of MIR339 mRNA CTD PMID:21203465 NCBI chr 5:139,355,405...139,355,500
Ensembl chr 5:139,355,405...139,355,500 		JBrowse link
G Mir450-1 microRNA 450-1 multiple interactions ISO [Resveratrol co-treated with Phytic Acid co-treated with ferulic acid co-treated with Quercetin] results in increased expression of MIR450A1 mRNA CTD PMID:21203465 NCBI chr  X:52,137,031...52,137,121
Ensembl chr  X:52,137,031...52,137,121 		JBrowse link
G Mir760 microRNA 760 multiple interactions ISO [Resveratrol co-treated with Phytic Acid co-treated with ferulic acid co-treated with Quercetin] results in increased expression of MIR760 mRNA CTD PMID:21203465 NCBI chr 3:122,087,234...122,087,352
Ensembl chr 3:122,087,234...122,087,352 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP ferulic acid inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein] CTD PMID:33140555 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions
increases expression		 EXP
ISO		 ferulic acid inhibits the reaction [sodium arsenate results in decreased expression of NFE2L2 mRNA]
[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with ferulic acid] promotes the reaction [[Ozone co-treated with Oxygen] results in increased localization of NFE2L2 protein]
ferulic acid results in increased expression of NFE2L2 mRNA		 CTD PMID:26270818 PMID:30503583 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions EXP ferulic acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] CTD PMID:33140555 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP [ferulic acid results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide; ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 mRNA]; ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]; ferulic acid inhibits the reaction [Lipopolysaccharides results in increased activity of NOS2 protein]; ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:21291945 PMID:22366099 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO Ferulic acid reverses the reaction[methotrexate decreases mRNA in the liver] RGD PMID:31889292 RGD:21201308 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity ISO ferulic acid results in decreased activity of PGD protein CTD PMID:25130191 NCBI chr 4:149,234,448...149,251,162
Ensembl chr 4:149,234,448...149,251,228 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression EXP ferulic acid results in increased expression of PIK3R1 mRNA CTD PMID:21870829 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma increases expression
multiple interactions		 EXP ferulic acid results in increased expression of PPARG mRNA
ferulic acid inhibits the reaction [sodium arsenite results in decreased expression of PPARG protein]		 CTD PMID:21870829 PMID:37393015 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha decreases expression
multiple interactions		 EXP
ISO		 ferulic acid results in decreased expression of PPARGC1A mRNA
ferulic acid inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein]
ferulic acid inhibits the reaction [sodium arsenate results in increased expression of PPARGC1A mRNA]		 CTD PMID:30503583 PMID:31029786 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTEN protein]; MIR17 mRNA affects the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTEN protein]]; PTEN protein inhibits the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]]; PTEN protein inhibits the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of AKT1 protein]]; PTEN protein inhibits the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]]; PTEN protein inhibits the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein]]; PTEN protein inhibits the reaction [ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTEN protein]] CTD PMID:35110471 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO ferulic acid results in decreased expression of PTGS1 mRNA CTD PMID:20816778 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions		 ISO
EXP		 ferulic acid results in decreased expression of PTGS2 protein
ferulic acid inhibits the reaction [Nicotine results in increased expression of PTGS2 protein]
ferulic acid analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 mRNA]; ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]		 CTD PMID:15841493 PMID:17436566 PMID:18068289 PMID:21291945 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO ferulic acid results in decreased phosphorylation of RB1 protein CTD PMID:15363954 PMID:15486966 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP
ISO		 ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased activity of and results in increased localization of RELA protein]; ferulic acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]
[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with ferulic acid] inhibits the reaction [[Ozone co-treated with Oxygen] results in increased localization of RELA protein]		 CTD PMID:21291945 PMID:26270818 PMID:33140555 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 decreases expression ISO ferulic acid results in decreased expression of SCD mRNA CTD PMID:20816778 NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303 		JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 multiple interactions
increases expression		 EXP ferulic acid inhibits the reaction [sodium arsenite results in decreased expression of SLC2A2 protein]
ferulic acid results in increased expression of SLC2A2 protein		 CTD PMID:37393015 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508 		JBrowse link
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 increases expression EXP ferulic acid results in increased expression of SLC2A4 mRNA CTD PMID:21870829 NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO ferulic acid inhibits the reaction [Thioacetamide results in increased phosphorylation of SMAD3 protein] CTD PMID:32278740 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276 		JBrowse link
G Snai2 snail family zinc finger 2 multiple interactions EXP ferulic acid inhibits the reaction [Silicon Dioxide results in increased expression of SNAI2 protein] CTD PMID:33428986 NCBI chr16:14,523,716...14,527,259
Ensembl chr16:14,523,716...14,527,249 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
increases expression		 EXP ferulic acid analog promotes the reaction [Colforsin results in increased expression of STAR mRNA]; ferulic acid analog promotes the reaction [Colforsin results in increased expression of STAR protein]; ferulic acid inhibits the reaction [sodium arsenate results in decreased expression of STAR mRNA]
ferulic acid results in increased expression of STAR mRNA		 CTD PMID:30503583 PMID:36279966 NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010 		JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 increases expression ISO ferulic acid results in increased expression of SULT2A1 mRNA CTD PMID:16443358 NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO ferulic acid inhibits the reaction [Thioacetamide results in increased expression of TGFB1 protein] CTD PMID:32278740 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions EXP ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR2 mRNA]; ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR2 protein] CTD PMID:21291945 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]; ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 protein]; ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] CTD PMID:21291945 PMID:33140555 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions		 EXP ferulic acid results in increased expression of TNF mRNA
ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; ferulic acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; ferulic acid inhibits the reaction [Silicon Dioxide results in increased expression of TNF protein]; ferulic acid inhibits the reaction [sodium arsenite results in increased expression of TNF protein]; ferulic acid inhibits the reaction [tyloxapol results in increased expression of TNF mRNA]		 CTD PMID:21291945 PMID:21870829 PMID:33140555 PMID:33428986 PMID:37076581 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tyr tyrosinase increases oxidation
multiple interactions		 ISO TYR protein results in increased oxidation of ferulic acid
[TYR protein results in increased oxidation of ferulic acid] which results in decreased abundance of Glutathione		 CTD PMID:20685355 NCBI chr 7:87,073,979...87,142,637
Ensembl chr 7:87,073,979...87,142,720 		JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 increases glucuronidation ISO UGT1A10 protein results in increased glucuronidation of ferulic acid CTD PMID:15117964 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of ferulic acid CTD PMID:15117964 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP ferulic acid inhibits the reaction [tyloxapol results in increased expression of VEGFA mRNA] CTD PMID:37076581 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Vim vimentin multiple interactions ISO
EXP		 ferulic acid inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of VIM protein]
ferulic acid inhibits the reaction [Silicon Dioxide results in increased expression of VIM protein]		 CTD PMID:31584213 PMID:33428986 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637 		JBrowse link
curcumin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A4galt alpha 1,4-galactosyltransferase multiple interactions ISO Curcumin inhibits the reaction [IL1B protein results in increased expression of A4GALT mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of A4GALT mRNA] CTD PMID:16819191 NCBI chr15:83,110,923...83,135,930
Ensembl chr15:83,110,923...83,135,975 		JBrowse link
G Aars1 alanyl-tRNA synthetase 1 decreases expression ISO Curcumin results in decreased expression of AARS1 mRNA CTD PMID:17198877 NCBI chr 8:111,759,781...111,784,237
Ensembl chr 8:111,759,776...111,784,296 		JBrowse link
G Abca1 ATP-binding cassette, sub-family A member 1 multiple interactions ISO Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 mRNA]; Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 protein]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 mRNA]]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 protein]]; SIRT6 protein promotes the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 mRNA]]; SIRT6 protein promotes the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 protein]] CTD PMID:33952798 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895 		JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A decreases expression
decreases response to substance
affects response to substance
multiple interactions		 ISO
EXP		 Curcumin analog results in decreased expression of ABCB1 protein; Curcumin results in decreased expression of ABCB1 mRNA; Curcumin results in decreased expression of ABCB1B mRNA
ABCB1 protein results in decreased susceptibility to Curcumin
ABCB1 affects the susceptibility to Curcumin
[Curcumin co-treated with Calcitriol] inhibits the reaction [Paclitaxel results in increased expression of ABCB1 protein]; Calcitriol promotes the reaction [Curcumin inhibits the reaction [Paclitaxel results in increased expression of ABCB1 protein]]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of ABCB1 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ABCB1 mRNA]
[Calcitriol co-treated with Curcumin] inhibits the reaction [Paclitaxel results in increased expression of ABCB1 protein]; [Curcumin co-treated with Calcitriol] inhibits the reaction [Paclitaxel results in increased expression of ABCB1 mRNA]; [Curcumin co-treated with Paclitaxel] results in increased expression of ABCB1 protein; [sulfinosine co-treated with Curcumin] results in decreased expression of ABCB1 mRNA; Calcitriol inhibits the reaction [[Curcumin co-treated with Paclitaxel] results in increased expression of ABCB1 protein]; Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]; Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]; Curcumin inhibits the reaction [[Calcitriol co-treated with Paclitaxel] results in increased expression of ABCB1 mRNA]; Curcumin inhibits the reaction [[Calcitriol co-treated with Paclitaxel] results in increased expression of ABCB1 protein]; Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]; Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]; Curcumin inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of ABCB1 mRNA]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of ABCB1 protein]; Curcumin results in decreased expression of and results in decreased activity of ABCB1 protein		 CTD PMID:15476675 PMID:17121181 PMID:18200517 PMID:18385293 PMID:18414057 More... NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B multiple interactions
decreases expression		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Curcumin results in decreased expression of ABCB1B protein]; [Curcumin results in decreased expression of ABCB1B protein] which results in increased susceptibility to Doxorubicin; Curcumin inhibits the reaction [[NFKB1 protein binds to RELA protein] which results in increased expression of ABCB1B mRNA]
Curcumin results in decreased expression of ABCB1B mRNA; Curcumin results in decreased expression of ABCB1B protein		 CTD PMID:18006147 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315 		JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 decreases activity
decreases expression		 ISO Curcumin results in decreased activity of ABCC1 protein
Curcumin analog results in decreased expression of ABCC1 mRNA		 CTD PMID:15885658 PMID:16021489 PMID:26409325 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 decreases activity
multiple interactions		 ISO
EXP		 Curcumin results in decreased activity of ABCC2 protein
[Curcumin co-treated with Acetaminophen] results in increased expression of ABCC2 mRNA; [Curcumin co-treated with Acetaminophen] results in increased expression of ABCC2 protein		 CTD PMID:15885658 PMID:35243748 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcc4 ATP-binding cassette, sub-family C member 4 multiple interactions ISO
EXP		 [Curcumin co-treated with Acetaminophen] results in increased expression of ABCC4 mRNA; [Curcumin co-treated with Acetaminophen] results in increased expression of ABCC4 protein CTD PMID:35243748 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631 		JBrowse link
G Abcc5 ATP-binding cassette, sub-family C member 5 multiple interactions ISO [Curcumin analog binds to and results in decreased activity of ABCC5 protein] which results in decreased export of Hyaluronic Acid; [Curcumin binds to and results in decreased activity of ABCC5 protein] which results in decreased export of Hyaluronic Acid; Curcumin analog binds to and results in decreased activity of ABCC5 protein; Curcumin analog inhibits the reaction [ABCC5 protein results in increased export of Hyaluronic Acid]; Curcumin binds to and results in decreased activity of ABCC5 protein; Curcumin inhibits the reaction [ABCC5 protein results in increased export of Hyaluronic Acid] CTD PMID:23978416 NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression ISO Curcumin results in increased expression of ABCG1 mRNA CTD PMID:16713233 PMID:21594647 NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) multiple interactions
decreases expression
increases expression		 ISO AHR protein promotes the reaction [Curcumin results in increased expression of ABCG2 protein]
Curcumin results in decreased expression of ABCG2 mRNA		 CTD PMID:17077187 PMID:33539684 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha increases phosphorylation
decreases expression
affects expression
multiple interactions		 ISO
EXP		 Curcumin results in increased phosphorylation of ACACA protein
Curcumin results in decreased expression of ACACA mRNA
Curcumin affects the expression of ACACA mRNA
Curcumin inhibits the reaction [bisphenol A results in increased expression of ACACA mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased expression of ACACA protein]; Curcumin inhibits the reaction [Dietary Fats results in decreased phosphorylation of ACACA protein]		 CTD PMID:18790744 PMID:19297423 PMID:27208389 PMID:37701206 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477 		JBrowse link
G Acacb acetyl-Coenzyme A carboxylase beta multiple interactions EXP Curcumin inhibits the reaction [bisphenol A results in increased expression of ACACB mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased expression of ACACB protein] CTD PMID:37701206 NCBI chr 5:114,284,748...114,388,822
Ensembl chr 5:114,284,596...114,388,822 		JBrowse link
G Ace angiotensin I converting enzyme multiple interactions ISO Curcumin inhibits the reaction [Paraquat affects the expression of ACE protein] CTD PMID:10666014 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Ace2 angiotensin converting enzyme 2 multiple interactions
affects binding		 ISO Curcumin inhibits the reaction [AGT protein results in increased expression of ACE2 protein]
Curcumin binds to ACE2 protein		 CTD PMID:26648693 PMID:34138966 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416 		JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases activity		 EXP
ISO		 [Curcumin co-treated with Niacin co-treated with ZM 241385] inhibits the reaction [Rotenone results in increased expression of ACHE protein]; Curcumin inhibits the reaction [Rotenone results in decreased activity of ACHE protein]; Curcumin inhibits the reaction [Rotenone results in increased expression of ACHE protein]; Curcumin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]
Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of ACHE protein]
Curcumin results in decreased activity of ACHE protein
Curcumin inhibits the reaction [Acrylamide results in increased activity of ACHE protein]; Curcumin inhibits the reaction [aluminum acetate results in decreased activity of ACHE protein]; Curcumin inhibits the reaction [cadmium sulfate results in increased expression of ACHE mRNA]; Curcumin inhibits the reaction [cadmium sulfate results in increased expression of ACHE protein]; Curcumin inhibits the reaction [lead acetate results in decreased activity of ACHE protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [[Atropine co-treated with Curcumin] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]]		 CTD PMID:18809455 PMID:20369229 PMID:21839772 PMID:22783142 PMID:25199698 More... NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728 		JBrowse link
G Ackr3 atypical chemokine receptor 3 increases expression ISO Curcumin results in increased expression of ACKR3 mRNA CTD PMID:21594647 NCBI chr 1:90,131,702...90,143,446
Ensembl chr 1:90,131,702...90,144,473 		JBrowse link
G Acly ATP citrate lyase affects expression
decreases expression		 EXP
ISO		 Curcumin affects the expression of ACLY mRNA
Curcumin results in decreased expression of ACLY mRNA		 CTD PMID:27208389 NCBI chr11:100,367,178...100,418,826
Ensembl chr11:100,367,179...100,418,826 		JBrowse link
G Aco2 aconitase 2, mitochondrial multiple interactions ISO Curcumin inhibits the reaction [Potassium Dichromate results in decreased activity of ACO2 protein] CTD PMID:25130536 NCBI chr15:81,756,664...81,799,338
Ensembl chr15:81,756,510...81,799,334 		JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions
decreases expression		 ISO
EXP		 [Arsenic Trioxide co-treated with Curcumin] inhibits the reaction [Cisplatin results in increased expression of ACTA2 mRNA]; Arsenic Trioxide promotes the reaction [Curcumin inhibits the reaction [Cisplatin results in increased expression of ACTA2 protein]]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]; Curcumin inhibits the reaction [Cisplatin results in increased expression of ACTA2 mRNA]; Curcumin inhibits the reaction [Cisplatin results in increased expression of ACTA2 protein]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of ACTA2 mRNA]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein]; Curcumin promotes the reaction [Arsenic Trioxide inhibits the reaction [Cisplatin results in increased expression of ACTA2 protein]]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in increased expression of ACTA2 mRNA]]
Curcumin inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein]
Curcumin results in decreased expression of ACTA2 mRNA; Curcumin results in decreased expression of ACTA2 protein		 CTD PMID:17355460 PMID:17531121 PMID:18006644 PMID:22683883 PMID:27363783 More... NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990 		JBrowse link
G Adam17 a disintegrin and metallopeptidase domain 17 multiple interactions ISO Curcumin inhibits the reaction [TNF protein results in increased expression of ADAM17 mRNA] CTD PMID:17666914 NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633 		JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif 4 increases expression ISO Curcumin results in increased expression of ADAMTS4 mRNA CTD PMID:18321735 NCBI chr 1:171,077,698...171,089,836
Ensembl chr 1:171,077,990...171,088,206 		JBrowse link
G Adcy9 adenylate cyclase 9 decreases expression ISO Curcumin results in decreased expression of ADCY9 mRNA CTD PMID:15713895 NCBI chr16:4,102,750...4,255,094
Ensembl chr16:4,105,393...4,238,362 		JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 decreases expression EXP Curcumin results in decreased expression of ADGRE1 mRNA CTD PMID:18403477 NCBI chr17:57,665,650...57,790,527
Ensembl chr17:57,665,691...57,790,527 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression
multiple interactions
affects expression		 EXP
ISO		 Curcumin results in increased expression of ADIPOQ mRNA; Curcumin results in increased expression of ADIPOQ protein
Curcumin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]]
Curcumin affects the expression of ADIPOQ mRNA
Curcumin inhibits the reaction [Fructose results in decreased expression of ADIPOQ protein]		 CTD PMID:18403477 PMID:26713546 PMID:27208389 PMID:28595985 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Adora2a adenosine A2a receptor multiple interactions EXP [Curcumin co-treated with Niacin co-treated with ZM 241385] inhibits the reaction [Rotenone results in increased expression of ADORA2A mRNA]; Curcumin inhibits the reaction [Rotenone results in increased expression of ADORA2A mRNA] CTD PMID:31820278 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618 		JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of AGER protein]]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of AGER protein] CTD PMID:29480285 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Agr2 anterior gradient 2 decreases expression ISO Curcumin results in decreased expression of AGR2 mRNA CTD PMID:17198877 NCBI chr12:36,042,924...36,054,080
Ensembl chr12:36,042,906...36,054,086 		JBrowse link
G Agt angiotensinogen multiple interactions ISO
EXP		 [Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]; [Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in increased expression of and results in increased phosphorylation of RELA protein]; [Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in increased expression of KIT protein]; [Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in increased expression of PCNA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]]; carboxymethyl-chitosan analog promotes the reaction [Curcumin inhibits the reaction [AGT protein modified form results in increased acetylation of TP53 protein]]; carboxymethyl-chitosan analog promotes the reaction [Curcumin inhibits the reaction [AGT protein modified form results in increased expression of BAX protein]]; carboxymethyl-chitosan analog promotes the reaction [Curcumin promotes the reaction [AGT protein modified form results in increased expression of BCL2 protein]]; Curcumin inhibits the reaction [AGT protein modified form promotes the reaction [TP53 protein binds to EP300 protein]]; Curcumin inhibits the reaction [AGT protein modified form results in increased cleavage of and results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [AGT protein modified form results in increased cleavage of PARP1 protein]; Curcumin inhibits the reaction [AGT protein modified form results in increased expression of and results in increased phosphorylation of and results in increased acetylation of TP53 protein]; Curcumin inhibits the reaction [AGT protein modified form results in increased expression of BAX protein]; Curcumin inhibits the reaction [AGT protein results in decreased expression of AGTR2 protein]; Curcumin inhibits the reaction [AGT protein results in increased expression of ACE2 protein]; Curcumin inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; Curcumin inhibits the reaction [AGT protein results in increased phosphorylation of SMAD2 protein]; Curcumin inhibits the reaction [AGT protein results in increased phosphorylation of SMAD3 protein]; Curcumin promotes the reaction [AGT protein modified form results in increased expression of BCL2 protein]
[Curcumin co-treated with Niacin co-treated with ZM 241385] inhibits the reaction [Rotenone results in increased expression of AGT protein]; Curcumin inhibits the reaction [Rotenone results in increased expression of AGT protein]		 CTD PMID:26612707 PMID:26648693 PMID:31820278 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions ISO Curcumin inhibits the reaction [AGT protein results in decreased expression of AGTR2 protein] CTD PMID:26648693 NCBI chr  X:21,350,863...21,355,072
Ensembl chr  X:21,350,783...21,355,403 		JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions
increases degradation
affects binding		 ISO
EXP		 AHR protein promotes the reaction [Curcumin results in increased expression of ABCG2 protein]
[Curcumin co-treated with resveratrol] inhibits the reaction [Benzo(a)pyrene results in increased activity of AHR protein]; Curcumin inhibits the reaction [Benzo(a)pyrene affects the localization of AHR protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased activity of AHR protein]; Curcumin inhibits the reaction [Methylcholanthrene binds to AHR protein]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ARNT protein]]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [AHR protein co-treated with ARNT protein]]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of AHR protein]; Curcumin promotes the reaction [Tetrachlorodibenzodioxin results in increased localization of AHR protein]
Curcumin results in increased degradation of AHR protein
Curcumin binds to AHR protein		 CTD PMID:17077187 PMID:17880909 PMID:18321868 PMID:19018768 PMID:25632966 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037 		JBrowse link
G Ak1 adenylate kinase 1 multiple interactions ISO [ERBB2 protein results in increased susceptibility to Curcumin analog] which results in decreased phosphorylation of AK1 protein CTD PMID:25866362 NCBI chr 2:32,511,770...32,525,070
Ensembl chr 2:32,511,770...32,525,070 		JBrowse link
G Akap6 A kinase anchor protein 6 increases expression
multiple interactions		 ISO
EXP		 Curcumin results in increased expression of AKAP6 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of AKAP6 mRNA]		 CTD PMID:18200517 PMID:18421014 NCBI chr12:52,745,371...53,202,351
Ensembl chr12:52,746,166...53,202,382 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression
multiple interactions
increases activity		 EXP
ISO		 Curcumin results in increased expression of AKR1B1 mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased expression of AKR1B1 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Curcumin results in increased expression of AKR1B1 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Curcumin results in increased expression of AKR1B1 protein]; AKT1 protein affects the reaction [Curcumin results in increased expression of AKR1B1 mRNA]; NFE2L2 protein promotes the reaction [Curcumin results in increased expression of AKR1B1 mRNA]; NFE2L2 protein promotes the reaction [Curcumin results in increased expression of AKR1B1 protein]; pyrazolanthrone inhibits the reaction [Curcumin results in increased expression of AKR1B1 mRNA]; SB 203580 inhibits the reaction [Curcumin results in increased expression of AKR1B1 mRNA]
Curcumin results in increased expression of AKR1B1 mRNA; Curcumin results in increased expression of AKR1B1 protein
Curcumin results in increased activity of AKR1B1 protein		 CTD PMID:17640564 PMID:18200517 PMID:18299980 PMID:18588981 NCBI chr 6:34,280,865...34,294,424
Ensembl chr 6:34,279,369...34,294,413 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions
affects phosphorylation
decreases expression
decreases phosphorylation
increases expression
increases phosphorylation
decreases activity		 ISO
EXP		 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased phosphorylation of AKT1 protein]; 4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]; [bisdemethoxycurcumin co-treated with Curcumin co-treated with demethoxycurcumin] inhibits the reaction [VEGF protein results in increased phosphorylation of AKT1 protein]; Arsenic Trioxide promotes the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]; calyculin A inhibits the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [ATF4 protein binds to AKT1 protein]; Curcumin inhibits the reaction [bisphenol A results in increased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [CXCL12 protein results in increased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [IL1B protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; Curcumin inhibits the reaction [Nicotine results in increased expression of AKT1 protein modified form]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of AKT1 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; Curcumin inhibits the reaction [Tunicamycin results in increased phosphorylation of AKT1 protein]; Curcumin promotes the reaction [Folfox protocol results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of AKT1 protein]; Curcumin results in decreased expression of and results in decreased phosphorylation of AKT1 protein; Curcumin results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of AKT1 protein; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of AKT1 protein]]; lonidamine promotes the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]; MIR532 affects the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]
Curcumin affects the phosphorylation of AKT1 protein
Curcumin analog results in decreased expression of AKT1 mRNA; Curcumin results in decreased expression of AKT1 protein
Curcumin results in increased expression of AKT1 protein
AKT1 protein affects the reaction [Curcumin results in increased expression of AKR1B1 mRNA]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Curcumin results in decreased phosphorylation of and results in decreased activity of AKT1 protein
AKT1 protein affects the reaction [Curcumin results in increased expression of HMOX1 mRNA]; ATF4 inhibits the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]
Curcumin results in decreased activity of AKT1 protein		 CTD PMID:16023083 PMID:16219905 PMID:17289836 PMID:17291458 PMID:17332930 More... NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Akt2 thymoma viral proto-oncogene 2 multiple interactions
decreases expression
decreases phosphorylation		 ISO
EXP		 4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased phosphorylation of AKT2 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of AKT2 protein modified form]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of AKT2 protein]; Curcumin inhibits the reaction [Tunicamycin results in increased phosphorylation of AKT2 protein]; Curcumin results in decreased expression of and results in decreased phosphorylation of AKT2 protein
Curcumin analog results in decreased expression of AKT2 mRNA
ATF4 inhibits the reaction [Curcumin results in decreased phosphorylation of AKT2 protein]		 CTD PMID:23452621 PMID:26409325 PMID:36640941 NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251 		JBrowse link
G Akt3 thymoma viral proto-oncogene 3 multiple interactions
decreases expression
decreases phosphorylation		 EXP
ISO		 ATF4 inhibits the reaction [Curcumin results in decreased phosphorylation of AKT3 protein]
Curcumin results in decreased expression of AKT3 protein
4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased phosphorylation of AKT3 protein]; Curcumin inhibits the reaction [Tunicamycin results in increased phosphorylation of AKT3 protein]; Curcumin results in decreased expression of and results in decreased phosphorylation of AKT3 protein; MIR532 affects the reaction [Curcumin results in decreased expression of AKT3 protein]		 CTD PMID:36640941 PMID:37471645 NCBI chr 1:176,847,642...177,091,688
Ensembl chr 1:176,847,639...177,085,769 		JBrowse link
G Alad aminolevulinate, delta-, dehydratase multiple interactions ISO
EXP		 [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased activity of ALAD protein]; Curcumin inhibits the reaction [Arsenic results in decreased activity of ALAD protein]
Curcumin inhibits the reaction [lead acetate results in decreased activity of ALAD protein]		 CTD PMID:22704994 PMID:23292317 NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155 		JBrowse link
G Alas1 aminolevulinic acid synthase 1 increases expression ISO Curcumin results in increased expression of ALAS1 mRNA CTD PMID:18299980 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853 		JBrowse link
G Alb albumin multiple interactions ISO [Curcumin analog co-treated with Hydrogels] inhibits the reaction [Aflatoxin B1 results in decreased expression of ALB protein]; [Curcumin analog co-treated with Hydrogels] results in increased expression of ALB protein; Curcumin inhibits the reaction [Acetaminophen results in decreased expression of ALB protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of ALB protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; Curcumin inhibits the reaction [Thioacetamide results in decreased expression of ALB protein]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of ALB protein]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in decreased expression of ALB protein]] CTD PMID:18204486 PMID:18809455 PMID:20804811 PMID:24704557 PMID:27288928 More... NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Alcam activated leukocyte cell adhesion molecule decreases expression ISO Curcumin results in decreased expression of ALCAM mRNA CTD PMID:33539684 NCBI chr16:52,069,359...52,273,444
Ensembl chr16:52,069,359...52,274,437 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 multiple interactions
decreases expression		 EXP
ISO		 [Calcitriol co-treated with Curcumin] inhibits the reaction [Paclitaxel results in decreased expression of ALDH1A1 protein]
[Calcitriol co-treated with Curcumin] promotes the reaction [Paclitaxel results in decreased expression of ALDH1A1 mRNA]; [Calcitriol co-treated with Paclitaxel] promotes the reaction [Curcumin results in decreased expression of ALDH1A1 mRNA]; [Curcumin co-treated with Calcitriol] inhibits the reaction [Paclitaxel results in decreased expression of ALDH1A1 protein]; [Curcumin co-treated with Paclitaxel] promotes the reaction [Calcitriol results in decreased expression of ALDH1A1 mRNA]; Curcumin promotes the reaction [Paclitaxel results in decreased expression of ALDH1A1 protein]; Paclitaxel promotes the reaction [Curcumin results in decreased expression of ALDH1A1 mRNA]
Curcumin results in decreased expression of ALDH1A1 mRNA; Curcumin results in decreased expression of ALDH1A1 protein		 CTD PMID:31628941 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829 		JBrowse link
G Aldoc aldolase C, fructose-bisphosphate decreases expression ISO Curcumin results in decreased expression of ALDOC mRNA CTD PMID:17198877 NCBI chr11:78,213,899...78,218,607
Ensembl chr11:78,213,794...78,218,607 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions
decreases activity		 ISO [Capsaicin co-treated with Curcumin] results in decreased activity of ALOX5 protein
Curcumin results in decreased activity of ALOX5 protein		 CTD PMID:16956363 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139 		JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 multiple interactions ISO Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of AMPD1 protein] CTD PMID:36924976 NCBI chr 3:102,981,330...103,007,038
Ensembl chr 3:102,981,330...103,007,036 		JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 increases expression ISO Curcumin results in increased expression of AMPD3 mRNA CTD PMID:18299980 NCBI chr 7:110,367,291...110,411,612
Ensembl chr 7:110,367,413...110,411,612 		JBrowse link
G Ankrd37 ankyrin repeat domain 37 decreases expression ISO Curcumin results in decreased expression of ANKRD37 mRNA CTD PMID:17198877 NCBI chr 8:46,449,945...46,452,904
Ensembl chr 8:46,449,939...46,458,744 		JBrowse link
G Ankrd50 ankyrin repeat domain 50 decreases expression ISO Curcumin results in decreased expression of ANKRD50 mRNA CTD PMID:17999991 NCBI chr 3:38,503,408...38,539,005
Ensembl chr 3:38,503,408...38,538,993 		JBrowse link
G Ankzf1 ankyrin repeat and zinc finger domain containing 1 decreases expression ISO Curcumin results in decreased expression of ANKZF1 mRNA CTD PMID:17198877 NCBI chr 1:75,168,794...75,176,031
Ensembl chr 1:75,168,795...75,176,031 		JBrowse link
G Aoc1 amine oxidase, copper-containing 1 multiple interactions ISO
EXP		 Curcumin inhibits the reaction [Methotrexate results in increased activity of AOC1 protein]
Curcumin inhibits the reaction [deoxynivalenol results in increased activity of AOC1 protein]		 CTD PMID:20885979 PMID:35817260 NCBI chr 6:48,872,189...48,886,122
Ensembl chr 6:48,849,830...48,886,122 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression
multiple interactions		 EXP
ISO		 Curcumin results in increased expression of APAF1 protein
Curcumin inhibits the reaction [Peroxynitrous Acid results in increased expression of APAF1 mRNA]		 CTD PMID:17277231 PMID:20869986 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632 		JBrowse link
G Apc APC, WNT signaling pathway regulator decreases expression ISO Curcumin results in decreased expression of APC mRNA CTD PMID:15713895 NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605 		JBrowse link
G Apoe apolipoprotein E affects expression EXP Curcumin affects the expression of APOE mRNA CTD PMID:27208389 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G App amyloid beta precursor protein multiple interactions
increases expression		 ISO Curcumin affects the reaction [APP protein binds to APP protein]; Curcumin inhibits the reaction [Copper results in increased expression of APP mRNA]; Curcumin inhibits the reaction [Hydrogen Peroxide results in increased expression of APP mRNA]; Curcumin inhibits the reaction [Paraquat results in increased expression of APP mRNA]; Curcumin inhibits the reaction [Paraquat results in increased expression of APP protein]
Curcumin results in increased expression of APP mRNA
[Curcumin analog co-treated with APP protein modified form] results in increased expression of NFE2L2 protein; [Curcumin co-treated with APP protein modified form] results in increased expression of NFE2L2 protein; Curcumin analog inhibits the reaction [APP protein modified form results in decreased activity of CAT protein]; Curcumin analog promotes the reaction [APP protein modified form results in decreased expression of KEAP1 protein]; Curcumin inhibits the reaction [APP protein modified form results in decreased activity of CAT protein]; Curcumin promotes the reaction [APP protein modified form results in decreased expression of KEAP1 protein]		 CTD PMID:18537544 PMID:18583042 PMID:27793699 PMID:30946834 PMID:31521693 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654 		JBrowse link
G Aqp3 aquaporin 3 decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of AQP3 protein
Curcumin inhibits the reaction [EGF protein results in increased expression of AQP3 protein]		 CTD PMID:18214481 NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183 		JBrowse link
G Aqp9 aquaporin 9 increases expression ISO Curcumin results in increased expression of AQP9 mRNA; Curcumin results in increased expression of AQP9 protein CTD PMID:34675983 NCBI chr 9:71,017,941...71,075,170
Ensembl chr 9:71,017,941...71,075,964 		JBrowse link
G Ar androgen receptor multiple interactions
decreases expression
decreases activity
increases expression		 ISO [[Quercetin co-treated with Curcumin] results in decreased methylation of AR promoter] which results in increased expression of AR mRNA; [[Quercetin co-treated with Curcumin] results in decreased methylation of AR promoter] which results in increased expression of AR protein; [Quercetin co-treated with Curcumin] results in decreased methylation of AR promoter; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of BAX protein]; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CASP3 protein]; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CDKN1A protein]; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CDKN1B protein]; Curcumin inhibits the reaction [AR protein results in increased expression of KLK3 mRNA]; Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [AR protein binds to KLK3 enhancer]]; Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [AR protein binds to TMPRSS2 enhancer]]; Curcumin inhibits the reaction [IL6 protein results in increased expression of AR mRNA]; Curcumin inhibits the reaction [IL6 protein results in increased expression of AR protein]; Curcumin promotes the reaction [Quercetin results in increased expression of AR mRNA]; Curcumin promotes the reaction [Quercetin results in increased expression of AR protein]; Quercetin promotes the reaction [Curcumin results in increased expression of AR mRNA]; Quercetin promotes the reaction [Curcumin results in increased expression of AR protein]
Curcumin results in decreased expression of AR mRNA; Curcumin results in decreased expression of AR protein
Curcumin results in decreased activity of AR protein
Curcumin results in increased expression of AR mRNA; Curcumin results in increased expression of AR protein		 CTD PMID:12497104 PMID:18676361 PMID:18719366 PMID:22258452 PMID:27132804 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821 		JBrowse link
G Arhgap24 Rho GTPase activating protein 24 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of ARHGAP24 mRNA] CTD PMID:18200517 NCBI chr 5:102,355,043...103,053,743
Ensembl chr 5:102,629,257...103,045,803 		JBrowse link
G Arhgap30 Rho GTPase activating protein 30 decreases expression ISO Curcumin results in decreased expression of ARHGAP30 mRNA CTD PMID:18421014 NCBI chr 1:171,216,528...171,237,808
Ensembl chr 1:171,216,522...171,237,866 		JBrowse link
G Arhgdib Rho, GDP dissociation inhibitor beta multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ARHGDIB mRNA] CTD PMID:18200517 NCBI chr 6:136,900,653...136,918,895
Ensembl chr 6:136,900,653...136,918,897 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions
decreases expression
increases degradation		 ISO
EXP		 Acetylcysteine inhibits the reaction [Curcumin results in increased degradation of ARNT protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in increased degradation of ARNT protein]; Curcumin results in increased ubiquitination of and results in increased degradation of ARNT protein
Curcumin results in decreased expression of ARNT protein
Curcumin inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ARNT protein]]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [AHR protein co-treated with ARNT protein]]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of ARNT protein]		 CTD PMID:16880289 PMID:17880909 PMID:18682687 PMID:19018768 NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551 		JBrowse link
G Atf1 activating transcription factor 1 multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of ATF1 mRNA] CTD PMID:23452621 NCBI chr15:100,125,729...100,159,129
Ensembl chr15:100,125,700...100,159,125 		JBrowse link
G Atf2 activating transcription factor 2 decreases expression ISO Curcumin analog results in decreased expression of ATF2 mRNA CTD PMID:26409325 NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Curcumin results in increased expression of ATF3 mRNA; Curcumin results in increased expression of ATF3 protein CTD PMID:15713895 PMID:18555241 PMID:18719366 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
decreases expression		 EXP
ISO		 ATF4 inhibits the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]; ATF4 inhibits the reaction [Curcumin results in decreased phosphorylation of AKT2 protein]; ATF4 inhibits the reaction [Curcumin results in decreased phosphorylation of AKT3 protein]; ATF4 inhibits the reaction [Curcumin results in decreased phosphorylation of MTOR protein]
ATF4 inhibits the reaction [Curcumin results in decreased expression of ATF4 protein]; ATF4 inhibits the reaction [Curcumin results in decreased expression of HK2 protein]; ATF4 inhibits the reaction [Curcumin results in decreased expression of LDHA protein]; ATF4 inhibits the reaction [Curcumin results in decreased expression of PKM protein]; ATF4 inhibits the reaction [Curcumin results in decreased expression of SLC2A1 protein]; Curcumin inhibits the reaction [ATF4 protein binds to AKT1 protein]; Curcumin inhibits the reaction [ATF4 protein binds to ATG4B protein]; Curcumin inhibits the reaction [Tunicamycin results in increased expression of ATF4 protein]		 CTD PMID:36640941 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742 		JBrowse link
G Atf6 activating transcription factor 6 increases expression EXP
ISO		 Curcumin results in increased expression of ATF6 protein
Curcumin results in increased expression of ATF6 mRNA		 CTD PMID:21793155 PMID:29723631 NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340 		JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase decreases expression
multiple interactions		 ISO
EXP		 Curcumin results in decreased expression of ATG4B protein
4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased expression of ATG4B protein]; Curcumin inhibits the reaction [ATF4 protein binds to ATG4B protein]; Curcumin inhibits the reaction [Tunicamycin results in increased expression of ATG4B protein]		 CTD PMID:36640941 NCBI chr 1:93,682,627...93,717,328
Ensembl chr 1:93,679,222...93,718,332 		JBrowse link
G Atg5 autophagy related 5 decreases expression
multiple interactions		 ISO
EXP		 Curcumin results in decreased expression of ATG5 protein
Curcumin inhibits the reaction [Tunicamycin results in increased expression of ATG5 protein]		 CTD PMID:36640941 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287 		JBrowse link
G Atm ataxia telangiectasia mutated multiple interactions
increases phosphorylation		 ISO [Isoflavones co-treated with Curcumin] results in increased phosphorylation of ATM protein
Curcumin results in increased phosphorylation of ATM protein		 CTD PMID:19401701 PMID:21134073 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Aurka aurora kinase A decreases expression ISO Curcumin analog results in decreased expression of AURKA mRNA CTD PMID:26409325 NCBI chr 2:172,198,116...172,212,825
Ensembl chr 2:172,198,110...172,212,455 		JBrowse link
G Aurkb aurora kinase B decreases expression ISO Curcumin analog results in decreased expression of AURKB mRNA CTD PMID:26409325 NCBI chr11:68,936,477...68,942,490
Ensembl chr11:68,936,473...68,942,490 		JBrowse link
G Axin1 axin 1 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [bisphenol A results in decreased expression of AXIN1 mRNA]
Curcumin results in increased expression of AXIN1 mRNA		 CTD PMID:25963729 NCBI chr17:26,350,294...26,414,784
Ensembl chr17:26,357,662...26,414,785 		JBrowse link
G B3galt6 UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6 increases expression ISO Curcumin results in increased expression of B3GALT6 mRNA CTD PMID:17198877 NCBI chr 4:156,073,923...156,077,135
Ensembl chr 4:156,073,923...156,077,106 		JBrowse link
G Bace1 beta-site APP cleaving enzyme 1 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Copper results in increased expression of BACE1 mRNA]; Curcumin inhibits the reaction [Hydrogen Peroxide results in increased expression of BACE1 mRNA]
Curcumin results in increased expression of BACE1 mRNA		 CTD PMID:18583042 PMID:31521693 NCBI chr 9:45,749,878...45,775,694
Ensembl chr 9:45,749,878...45,775,697 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression
multiple interactions		 ISO Curcumin results in increased expression of BAD mRNA; Curcumin results in increased expression of BAD protein
[arsenic trioxide co-treated with Curcumin] results in increased expression of BAD protein
Curcumin inhibits the reaction [tert-Butylhydroperoxide results in increased expression of BAD protein]		 CTD PMID:15569404 PMID:19235267 PMID:27430728 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
decreases expression
increases expression
increases response to substance		 ISO
EXP		 TNFSF10 protein promotes the reaction [Curcumin results in increased expression of BAK1 protein]
Curcumin results in decreased expression of BAK1 mRNA
Curcumin results in increased expression of BAK1 mRNA; Curcumin results in increased expression of BAK1 protein
BAK1 protein results in increased susceptibility to Curcumin		 CTD PMID:17277231 PMID:17332930 PMID:18226269 PMID:33582110 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983 		JBrowse link
G Bax BCL2-associated X protein multiple interactions
increases response to substance
increases expression
affects localization
decreases expression
affects expression		 ISO
EXP		 [Arsenic Trioxide co-treated with Curcumin] results in increased expression of BAX protein; [bicalutamide co-treated with Curcumin co-treated with Quercetin] results in increased expression of BAX protein; [Curcumin co-treated with Arsenic Trioxide] results in increased expression of BAX protein; [Curcumin co-treated with Quercetin] results in increased expression of BAX protein; [Curcumin co-treated with Sirolimus] results in increased expression of BAX; [Doxorubicin co-treated with Curcumin] results in increased expression of BAX mRNA; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of BAX protein]; Arsenic Trioxide promotes the reaction [Curcumin affects the localization of BAX protein]; Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX protein]; Curcumin inhibits the reaction [bisphenol A results in decreased expression of BAX protein]; Curcumin inhibits the reaction [Paraquat results in increased expression of BAX protein]; Curcumin promotes the reaction [Arsenic Trioxide affects the localization of BAX protein]; Curcumin promotes the reaction [lonidamine affects the localization of BAX protein]; Curcumin promotes the reaction [Paclitaxel promotes the reaction [Calcitriol results in increased expression of BAX protein]]; Curcumin promotes the reaction [Paclitaxel results in increased expression of BAX protein]; Dihydrotestosterone inhibits the reaction [[Curcumin co-treated with Quercetin] results in increased expression of BAX protein]; lonidamine promotes the reaction [Curcumin affects the localization of BAX protein]; Paclitaxel promotes the reaction [Curcumin results in increased expression of BAX protein]; piperine inhibits the reaction [Curcumin results in decreased expression of BAX protein]; TNFSF10 protein promotes the reaction [Curcumin results in increased expression of BAX protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of BAX protein]
[Curcumin co-treated with Quercetin] inhibits the reaction [Benzo(a)pyrene results in decreased expression of BAX protein]; Curcumin affects the localization of and results in increased expression of and results in increased activity of BAX protein; Curcumin inhibits the reaction [Benzo(a)pyrene results in decreased expression of BAX protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of BAX protein]
BAX protein results in increased susceptibility to Curcumin
2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in increased expression of BAX mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in increased expression of BAX protein]; [Curcumin analog co-treated with Hydrogels] inhibits the reaction [Aflatoxin B1 results in increased expression of BAX mRNA]; carboxymethyl-chitosan analog promotes the reaction [Curcumin inhibits the reaction [AGT protein modified form results in increased expression of BAX protein]]; carboxymethyl-chitosan analog promotes the reaction [Curcumin results in decreased expression of BAX protein]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [AGT protein modified form results in increased expression of BAX protein]; Curcumin inhibits the reaction [aristolochic acid I results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [Ketamine results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [Ketamine results in increased expression of BAX protein]; Curcumin inhibits the reaction [Peroxynitrous Acid results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [Peroxynitrous Acid results in increased expression of BAX protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of BAX protein]; Curcumin inhibits the reaction [Streptozocin affects the expression of BAX protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [tert-Butylhydroperoxide results in increased expression of BAX protein]
Curcumin results in increased expression of BAX mRNA; Curcumin results in increased expression of BAX protein
Curcumin results in decreased expression of BAX mRNA; Curcumin results in decreased expression of BAX protein
Curcumin affects the expression of BAX protein		 CTD PMID:15569404 PMID:17096185 PMID:17277231 PMID:17332930 PMID:17531121 More... NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bbc3 BCL2 binding component 3 increases expression
multiple interactions
decreases expression		 ISO
EXP		 Curcumin results in increased expression of BBC3 mRNA
Curcumin inhibits the reaction [Doxorubicin results in increased expression of BBC3 protein]
Curcumin results in decreased expression of BBC3 mRNA		 CTD PMID:17332930 PMID:22714040 PMID:34047412 NCBI chr 7:16,042,307...16,052,130
Ensembl chr 7:16,042,318...16,052,130 		JBrowse link
G Bcl10 B cell leukemia/lymphoma 10 multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of BCL10 mRNA] CTD PMID:23452621 NCBI chr 3:145,630,017...145,640,121
Ensembl chr 3:145,628,559...145,640,111 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
decreases expression
increases expression		 ISO
EXP		 [Arsenic Trioxide co-treated with Curcumin] affects the expression of BCL2 protein; [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] which results in decreased expression of BCL2 protein; [Curcumin co-treated with Arsenic Trioxide] results in decreased expression of BCL2 protein; [Curcumin co-treated with Calcitriol] promotes the reaction [Paclitaxel results in decreased expression of BCL2 protein]; [Curcumin co-treated with Isoflavones] results in decreased expression of BCL2 protein; [Curcumin co-treated with Sirolimus] results in decreased expression of BCL2; [Curcumin results in increased expression of SERPINB5] which results in decreased expression of BCL2 protein; [Dihydrotestosterone co-treated with Curcumin co-treated with Quercetin] results in increased expression of BCL2 protein; [Doxorubicin co-treated with Curcumin] results in decreased expression of BCL2 mRNA; [piperine co-treated with Curcumin] results in decreased expression of BCL2 protein; [Vitamin E co-treated with Curcumin] results in decreased expression of BCL2 protein; Curcumin inhibits the reaction [Docetaxel results in increased phosphorylation of BCL2 protein]; Curcumin inhibits the reaction [Nicotine results in increased expression of BCL2 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of BCL2 mRNA]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of BCL2 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2 protein]; Curcumin promotes the reaction [Calcitriol promotes the reaction [Paclitaxel results in decreased expression of BCL2 protein]]; Curcumin promotes the reaction [Paclitaxel results in decreased expression of BCL2 protein]; Curcumin promotes the reaction [sodium arsenite results in decreased expression of BCL2 protein]; Curcumin results in increased ubiquitination of and results in increased degradation of BCL2 protein; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2 protein]]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Curcumin results in increased ubiquitination of and results in increased degradation of BCL2 protein]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in decreased expression of BCL2 protein]]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of BCL2 protein]
2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in decreased expression of BCL2 mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in decreased expression of BCL2 protein]; [Curcumin analog co-treated with Hydrogels] inhibits the reaction [Aflatoxin B1 results in decreased expression of BCL2 mRNA]; carboxymethyl-chitosan analog promotes the reaction [Curcumin promotes the reaction [AGT protein modified form results in increased expression of BCL2 protein]]; carboxymethyl-chitosan analog promotes the reaction [Curcumin results in increased expression of BCL2 protein]; Curcumin affects the reaction [Ketamine results in decreased expression of BCL2 protein]; Curcumin analog inhibits the reaction [Copper Sulfate results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [bisphenol A results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [Colistin results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [Copper Sulfate results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [Cyclosporine results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [Ketamine results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [Peroxynitrous Acid results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [Peroxynitrous Acid results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [Streptozocin affects the expression of BCL2 protein]; Curcumin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of BCL2 protein]; Curcumin promotes the reaction [AGT protein modified form results in increased expression of BCL2 protein]
[Curcumin co-treated with Gemcitabine] results in decreased expression of BCL2 protein; [Quercetin co-treated with Curcumin] inhibits the reaction [Benzo(a)pyrene results in increased expression of BCL2 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of BCL2 protein]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of BCL2 protein]
Curcumin results in decreased expression of BCL2 mRNA; Curcumin results in decreased expression of BCL2 protein
Curcumin analog results in decreased expression of BCL2 mRNA; Curcumin results in decreased expression of BCL2 mRNA; Curcumin results in decreased expression of BCL2 protein
Curcumin results in increased expression of BCL2 mRNA; Curcumin results in increased expression of BCL2 protein		 CTD PMID:12497104 PMID:14724571 PMID:15569404 PMID:16023083 PMID:16219905 More... NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of BCL2A1 mRNA
Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2A1 mRNA]		 CTD PMID:16219905 PMID:17596214 NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880 		JBrowse link
G Bcl2l1 BCL2-like 1 multiple interactions
decreases expression
increases expression		 ISO
EXP		 [Curcumin co-treated with Doxorubicin] affects the expression of BCL2L1 mRNA; [Curcumin co-treated with Isoflavones] results in decreased expression of BCL2L1 protein; Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2L1 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of BCL2L1 mRNA]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of BCL2L1 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2L1 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2L1 protein]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2L1 protein]]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of BCL2L1 protein]
Curcumin analog results in decreased expression of BCL2L1 mRNA; Curcumin results in decreased expression of BCL2L1 mRNA; Curcumin results in decreased expression of BCL2L1 protein
Curcumin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of BCL2L1 protein]
[Curcumin co-treated with Gemcitabine] results in decreased expression of BCL2L1 protein
Curcumin results in increased expression of BCL2L1 mRNA		 CTD PMID:12497104 PMID:15569404 PMID:15911101 PMID:16023083 PMID:16173963 More... NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Bcl2l11 BCL2 like 11 increases expression
multiple interactions		 ISO Curcumin results in increased expression of BCL2L11 mRNA
[arsenic trioxide co-treated with Curcumin] results in increased expression of BCL2L11 protein		 CTD PMID:17332930 PMID:27430728 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467 		JBrowse link
G Bcl2l2 BCL2-like 2 increases expression
multiple interactions		 ISO Curcumin results in increased expression of BCL2L2 mRNA
[arsenic trioxide co-treated with Curcumin] affects the expression of BCL2L2 protein		 CTD PMID:16101141 PMID:27430728 NCBI chr14:55,120,900...55,125,691
Ensembl chr14:55,120,834...55,125,691 		JBrowse link
G Bcl3 B cell leukemia/lymphoma 3 multiple interactions EXP
ISO		 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BCL3 mRNA]
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of BCL3 mRNA]		 CTD PMID:18200517 PMID:23452621 NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695 		JBrowse link
G Bcor BCL6 interacting corepressor increases expression ISO Curcumin results in increased expression of BCOR mRNA CTD PMID:17198877 NCBI chr  X:11,902,976...12,026,769
Ensembl chr  X:11,902,979...12,026,594 		JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions
affects expression
increases expression		 ISO
EXP		 [Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of BDNF mRNA]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of BDNF protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of BDNF protein]
[Docosahexaenoic Acids co-treated with Curcumin] results in increased expression of BDNF mRNA; Curcumin inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BDNF protein]; Curcumin inhibits the reaction [Morphine results in increased expression of BDNF mRNA]
Curcumin affects the expression of BDNF protein
Curcumin results in increased expression of BDNF protein		 CTD PMID:17022948 PMID:17617388 PMID:17827730 PMID:19033880 PMID:22911773 More... NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352 		JBrowse link
G Becn1 beclin 1, autophagy related increases expression
decreases expression		 ISO Curcumin results in increased expression of BECN1 protein
Curcumin results in decreased expression of BECN1 protein		 CTD PMID:34634291 PMID:36640941 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Bgn biglycan multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of BGN mRNA] CTD PMID:18200517 NCBI chr  X:72,527,207...72,539,542
Ensembl chr  X:72,527,208...72,539,539 		JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [arsenic trioxide co-treated with Curcumin] results in decreased expression of BID protein; [arsenic trioxide co-treated with Curcumin] results in increased expression of BID protein; Curcumin promotes the reaction [arsenic trioxide results in increased activity of BID protein] CTD PMID:20605902 PMID:27430728 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression
multiple interactions		 ISO Curcumin analog results in decreased expression of BIRC2 mRNA; Curcumin results in decreased expression of BIRC2 mRNA; Curcumin results in decreased expression of BIRC2 protein
Curcumin inhibits the reaction [Nicotine results in increased expression of BIRC2 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of BIRC2 protein]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of BIRC2 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC2 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]]		 CTD PMID:16023083 PMID:16219905 PMID:16243823 PMID:17596214 PMID:17640567 More... NCBI chr 9:7,818,227...7,837,123
Ensembl chr 9:7,818,228...7,837,065 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions
increases expression
decreases expression		 ISO
EXP		 [arsenic trioxide co-treated with Curcumin] results in decreased expression of BIRC3 protein; [Curcumin co-treated with Doxorubicin] affects the expression of BIRC3 mRNA; Curcumin inhibits the reaction [Paclitaxel results in increased expression of BIRC3 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC3 mRNA]
[Curcumin co-treated with Gemcitabine] results in decreased expression of BIRC3 protein
Curcumin results in increased expression of BIRC3 mRNA
Curcumin results in decreased expression of BIRC3 mRNA; Curcumin results in decreased expression of BIRC3 protein		 CTD PMID:15911101 PMID:16101141 PMID:16219905 PMID:16243823 PMID:17440100 More... NCBI chr 9:7,848,698...7,873,199
Ensembl chr 9:7,848,700...7,873,187 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression		 ISO
EXP		 [Arsenic Trioxide co-treated with Curcumin] results in decreased expression of BIRC5 protein; Curcumin inhibits the reaction [Benzo(a)pyrene results in decreased expression of BIRC5 protein]; Curcumin inhibits the reaction [Nicotine results in increased expression of BIRC5 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of BIRC5 protein]; Curcumin inhibits the reaction [Trichloroethylene results in increased expression of BIRC5 protein]
Curcumin inhibits the reaction [Doxorubicin results in decreased expression of BIRC5 protein]
Curcumin analog results in decreased expression of BIRC5 mRNA; Curcumin results in decreased expression of BIRC5 mRNA; Curcumin results in decreased expression of BIRC5 protein
[Curcumin co-treated with Gemcitabine] results in decreased expression of BIRC5 protein		 CTD PMID:16023083 PMID:17440100 PMID:17596214 PMID:17671737 PMID:18593936 More... NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569 		JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 increases expression
multiple interactions		 ISO Curcumin results in increased expression of BIRC7 mRNA
[arsenic trioxide co-treated with Curcumin] results in increased expression of BIRC7 protein		 CTD PMID:15911101 PMID:27430728 NCBI chr 2:180,570,402...180,575,803
Ensembl chr 2:180,570,816...180,575,803 		JBrowse link
G Bmp2 bone morphogenetic protein 2 decreases expression EXP Curcumin results in decreased expression of BMP2 mRNA CTD PMID:27237783 NCBI chr 2:133,394,079...133,404,816
Ensembl chr 2:133,394,079...133,404,805 		JBrowse link
G Brca1 breast cancer 1, early onset multiple interactions ISO Curcumin inhibits the reaction [Furazolidone results in increased expression of BRCA1 protein] CTD PMID:27996348 NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781 		JBrowse link
G Bsg basigin decreases response to substance EXP BSG protein results in decreased susceptibility to Curcumin CTD PMID:18379992 NCBI chr10:79,540,192...79,547,813
Ensembl chr10:79,540,325...79,547,803 		JBrowse link
G C1qa complement component 1, q subcomponent, alpha polypeptide decreases expression EXP Curcumin results in decreased expression of C1QA mRNA CTD PMID:19555370 NCBI chr 4:136,623,227...136,626,155
Ensembl chr 4:136,623,228...136,626,114 		JBrowse link
G C1qb complement component 1, q subcomponent, beta polypeptide multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C1QB mRNA] CTD PMID:18200517 NCBI chr 4:136,607,437...136,613,511
Ensembl chr 4:136,607,440...136,613,498 		JBrowse link
G C3 complement component 3 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C3 mRNA] CTD PMID:18200517 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G C4b complement C4B (Chido blood group) multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of C4B mRNA] CTD PMID:18200517 NCBI chr17:34,947,249...34,962,876
Ensembl chr17:34,947,354...34,962,856 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP
ISO		 [Docosahexaenoic Acids co-treated with Curcumin] results in increased expression of CAMK2A mRNA
Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of CAMK2A protein]		 CTD PMID:22911773 PMID:29723552 NCBI chr18:61,058,704...61,121,224
Ensembl chr18:61,058,690...61,121,224 		JBrowse link
G Capg capping actin protein, gelsolin like multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CAPG mRNA] CTD PMID:18200517 NCBI chr 6:72,515,265...72,539,966
Ensembl chr 6:72,521,374...72,539,966 		JBrowse link
G Car9 carbonic anhydrase 9 decreases expression ISO Curcumin results in decreased expression of CAR9 mRNA CTD PMID:18299980 NCBI chr 4:43,507,026...43,513,729
Ensembl chr 4:43,506,966...43,513,729 		JBrowse link
G Casp1 caspase 1 increases expression
multiple interactions		 ISO
EXP		 Curcumin results in increased expression of CASP1 mRNA
[Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of CASP1 protein]; [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of CASP1 mRNA]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of CASP1 protein]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of CASP1 mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of CASP1 mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of CASP1 protein]
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of CASP1 mRNA]		 CTD PMID:16101141 PMID:23452621 PMID:34998855 PMID:35063475 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290 		JBrowse link
G Casp12 caspase 12 increases expression
multiple interactions		 EXP
ISO		 Curcumin results in increased expression of CASP12 protein
Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein]		 CTD PMID:21793155 PMID:25541178 NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032 		JBrowse link
G Casp2 caspase 2 increases expression ISO Curcumin results in increased expression of CASP2 mRNA CTD PMID:16101141 NCBI chr 6:42,241,942...42,259,442
Ensembl chr 6:42,241,919...42,259,442 		JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression
increases activity
increases expression
decreases activity
increases cleavage		 ISO
EXP		 [Arsenic Trioxide co-treated with Curcumin] results in increased expression of CASP3 protein; [bicalutamide co-treated with Curcumin co-treated with Quercetin] results in increased expression of CASP3 protein; [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] which results in increased cleavage of CASP3 protein; [Curcumin co-treated with Arsenic Trioxide] results in decreased expression of and results in increased cleavage of CASP3 protein; [Curcumin co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein; [Curcumin co-treated with lonidamine] results in increased cleavage of CASP3 protein; [Curcumin co-treated with Quercetin] results in increased expression of CASP3 protein; [Curcumin co-treated with Sirolimus] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [Curcumin results in increased activity of CASP3 protein]; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CASP3 protein]; Arsenic Trioxide promotes the reaction [Curcumin results in increased expression of CASP3 protein modified form]; Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP3 protein modified form]; Curcumin inhibits the reaction [quinocetone results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased cleavage of CASP3 protein]; Curcumin promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; Curcumin results in increased cleavage of and results in increased activity of CASP3 protein; Dihydrotestosterone inhibits the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CASP3 protein]; Glutathione inhibits the reaction [Curcumin results in increased activity of CASP3 protein]; piperine inhibits the reaction [Curcumin results in decreased expression of CASP3 protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of CASP3 protein]; zinc protoporphyrin inhibits the reaction [Curcumin inhibits the reaction [quinocetone results in increased activity of CASP3 protein]]
Curcumin results in decreased expression of CASP3 mRNA; Curcumin results in decreased expression of CASP3 protein
Curcumin analog results in increased activity of CASP3 protein; Curcumin results in increased activity of CASP3; Curcumin results in increased activity of CASP3 protein
Curcumin results in increased expression of CASP3 mRNA; Curcumin results in increased expression of CASP3 protein; Curcumin results in increased expression of CASP3 protein modified form
[Curcumin co-treated with Gemcitabine] results in decreased expression of CASP3 protein; [Curcumin co-treated with Niacin co-treated with ZM 241385] inhibits the reaction [Rotenone results in increased activity of CASP3 protein]; [Quercetin co-treated with Curcumin] inhibits the reaction [Benzo(a)pyrene results in decreased activity of CASP3 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in decreased activity of CASP3 protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [Rotenone results in increased activity of CASP3 protein]; Curcumin results in increased cleavage of and results in increased activity of CASP3 protein; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in decreased expression of CASP3 protein modified form]
Curcumin results in decreased activity of CASP3 protein
[Curcumin analog co-treated with Hydrogels] inhibits the reaction [Aflatoxin B1 results in increased expression of CASP3 mRNA]; Curcumin analog inhibits the reaction [Copper Sulfate results in increased secretion of CASP3 protein]; Curcumin analog inhibits the reaction [Rotenone results in increased expression of CASP3 protein modified form]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of CASP3 mRNA]; Curcumin inhibits the reaction [AGT protein modified form results in increased cleavage of and results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [aristolochic acid I results in increased expression of and results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [aristolochic acid I results in increased expression of CASP3 mRNA]; Curcumin inhibits the reaction [Atrazine results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [bisphenol A results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [Colistin results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [Copper Sulfate results in increased secretion of CASP3 protein]; Curcumin inhibits the reaction [Cyclosporine results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [Ketamine results in increased expression of CASP3 mRNA]; Curcumin inhibits the reaction [Ketamine results in increased expression of CASP3 protein modified form]; Curcumin inhibits the reaction [Ketamine results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [Peroxynitrous Acid results in increased cleavage of and results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [Peroxynitrous Acid results in increased expression of CASP3 mRNA]; Curcumin inhibits the reaction [Rotenone results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of CASP3 protein]; Curcumin results in decreased cleavage of and results in decreased activity of CASP3 protein
Curcumin results in increased cleavage of CASP3 protein		 CTD PMID:15095415 PMID:15569404 PMID:16023083 PMID:16101141 PMID:17041101 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp4 caspase 4, apoptosis-related cysteine peptidase increases expression ISO Curcumin results in increased expression of CASP4 mRNA CTD PMID:16101141 NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783 		JBrowse link
G Casp7 caspase 7 multiple interactions
increases expression
decreases expression		 ISO [Calcitriol co-treated with Curcumin] promotes the reaction [Paclitaxel results in increased expression of CASP7 protein]; [Curcumin co-treated with Sirolimus] results in increased activity of CASP7 protein; Calcitriol inhibits the reaction [Curcumin inhibits the reaction [Paclitaxel results in increased expression of CASP7 protein]]; Curcumin inhibits the reaction [Calcitriol inhibits the reaction [Paclitaxel results in increased expression of CASP7 protein]]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of CASP7 protein]; Curcumin results in increased cleavage of and results in increased activity of CASP7 protein
Curcumin results in increased expression of CASP7 protein
Curcumin results in decreased expression of CASP7 mRNA		 CTD PMID:16023083 PMID:16101141 PMID:19373661 PMID:31628941 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776 		JBrowse link
G Casp8 caspase 8 increases activity
multiple interactions
increases cleavage
decreases expression		 ISO Curcumin results in increased activity of CASP8 protein
Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP8 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]
Curcumin results in increased cleavage of CASP8 protein
Curcumin results in decreased expression of CASP8 mRNA; Curcumin results in decreased expression of CASP8 protein
[Arsenic Trioxide co-treated with Curcumin] results in increased expression of CASP8 protein; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of CASP8 mRNA]; Curcumin results in increased cleavage of and results in increased activity of CASP8 protein; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride promotes the reaction [Curcumin results in increased cleavage of CASP8 protein]		 CTD PMID:14555224 PMID:16173963 PMID:17096185 PMID:17148446 PMID:22523229 More... NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 decreases expression
multiple interactions
increases activity
increases expression
increases cleavage		 ISO
EXP		 Curcumin results in decreased expression of CASP9 mRNA; Curcumin results in decreased expression of CASP9 protein
Curcumin inhibits the reaction [aristolochic acid I results in increased expression of and results in increased cleavage of CASP9 protein]; Curcumin inhibits the reaction [aristolochic acid I results in increased expression of CASP9 mRNA]; Curcumin inhibits the reaction [Peroxynitrous Acid results in increased cleavage of and results in increased activity of CASP9 protein]; Curcumin inhibits the reaction [Peroxynitrous Acid results in increased expression of CASP9 mRNA]
Curcumin results in increased activity of CASP9 protein
Curcumin results in increased expression of CASP9 mRNA; Curcumin results in increased expression of CASP9 protein
[Curcumin co-treated with Gemcitabine] results in decreased expression of CASP9 protein; [Quercetin co-treated with Curcumin] inhibits the reaction [Benzo(a)pyrene results in decreased activity of CASP9 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in decreased activity of CASP9 protein]; Curcumin inhibits the reaction [Dibutyl Phthalate results in increased expression of CASP9 protein]; Curcumin results in increased cleavage of and results in increased activity of CASP9 protein
Curcumin results in increased cleavage of CASP9 protein
[Curcumin co-treated with Arsenic Trioxide] results in increased cleavage of CASP9 protein; [Curcumin co-treated with Calcitriol] promotes the reaction [Paclitaxel results in increased expression of CASP9 protein]; [Curcumin co-treated with lonidamine] results in increased cleavage of CASP9 protein; [Curcumin co-treated with Sirolimus] results in increased activity of CASP9 protein; [Doxorubicin co-treated with Curcumin] results in increased expression of CASP9 mRNA; [Paclitaxel co-treated with Calcitriol] promotes the reaction [Curcumin results in increased expression of CASP9 protein]; [Paclitaxel co-treated with Curcumin] promotes the reaction [Calcitriol results in increased expression of CASP9 protein]; Curcumin inhibits the reaction [quinocetone results in increased activity of CASP9 protein]; Curcumin promotes the reaction [[Calcitriol co-treated with Paclitaxel] results in increased expression of CASP9 protein]; Curcumin results in increased cleavage of and results in increased activity of CASP9 protein; Paclitaxel promotes the reaction [Curcumin results in increased expression of CASP9 protein]; zinc protoporphyrin inhibits the reaction [Curcumin inhibits the reaction [quinocetone results in increased activity of CASP9 protein]]		 CTD PMID:14555224 PMID:16023083 PMID:16101141 PMID:17148446 PMID:17277231 More... NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cat catalase multiple interactions
increases expression
increases activity		 ISO
EXP		 [arsenite co-treated with Curcumin] results in increased expression of CAT protein; Curcumin inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of CAT mRNA]; Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of CAT protein]; Curcumin inhibits the reaction [Oxaliplatin results in decreased activity of CAT protein]; Curcumin inhibits the reaction [quinocetone results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Vehicle Emissions promotes the reaction [Cisplatin results in decreased activity of CAT protein]]; Curcumin inhibits the reaction [Vehicle Emissions results in decreased activity of CAT protein]
Curcumin results in increased expression of CAT protein
Curcumin results in increased activity of CAT protein
Curcumin inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Acetaminophen results in decreased expression of CAT protein]; Curcumin inhibits the reaction [Acrylamide results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of CAT mRNA]; Curcumin inhibits the reaction [Chloranil results in decreased activity of CAT protein]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CAT mRNA]; Curcumin inhibits the reaction [Paraquat results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Rotenone results in decreased activity of CAT protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of CAT mRNA]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of CAT]; Curcumin metabolite inhibits the reaction [Acetaminophen results in decreased expression of CAT protein]; sodium arsenite inhibits the reaction [Curcumin results in increased activity of CAT protein]
Curcumin results in increased expression of CAT mRNA
[Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased activity of CAT protein]; [Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in decreased expression of CAT mRNA]; [Vitamin E co-treated with Curcumin] inhibits the reaction [Thyroxine results in decreased activity of CAT protein]; Curcumin analog inhibits the reaction [APP protein modified form results in decreased activity of CAT protein]; Curcumin analog inhibits the reaction [Monocrotaline results in increased activity of CAT protein]; Curcumin analog inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased activity of CAT protein]; Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with Tobacco Smoke Pollution] results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Acetaminophen results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Acrylonitrile results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased activity of CAT protein]; Curcumin inhibits the reaction [APP protein modified form results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Arsenic results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Chloroquine results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Colistin results in decreased expression of CAT protein]; Curcumin inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Fenitrothion results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Hexachlorocyclohexane results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Indomethacin results in decreased activity of CAT protein]; Curcumin inhibits the reaction [methylmercuric chloride results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Oxygen deficiency results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Paraquat results in decreased activity of CAT protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Sodium Selenite results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Curcumin inhibits the reaction [Thyroxine results in decreased expression of CAT mRNA]; Curcumin inhibits the reaction [Thyroxine results in decreased expression of CAT protein]		 CTD PMID:16770732 PMID:17076682 PMID:17351913 PMID:17461496 PMID:18299980 More... NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Cbr1 carbonyl reductase 1 multiple interactions ISO [[Curcumin binds to and results in decreased activity of CBR1 protein] which results in decreased reduction of Daunorubicin] which results in decreased chemical synthesis of daunorubicinol; [Curcumin binds to and results in decreased activity of CBR1 protein] which results in decreased reduction of Daunorubicin; Curcumin binds to and results in decreased activity of CBR1 protein; Curcumin inhibits the reaction [CBR1 protein results in increased reduction of 2,3-hexanedione]; Curcumin inhibits the reaction [NADP metabolite binds to and results in increased activity of CBR1 protein] CTD PMID:25541467 NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393 		JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 increases expression ISO
EXP		 Curcumin results in increased expression of CCAR1 protein CTD PMID:21594647 NCBI chr10:62,579,707...62,628,147
Ensembl chr10:62,579,707...62,628,065 		JBrowse link
G Ccdc116 coiled-coil domain containing 116 increases expression EXP Curcumin results in increased expression of CCDC116 mRNA CTD PMID:18200517 NCBI chr16:16,956,928...16,965,459
Ensembl chr16:16,956,928...16,965,093 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases expression
increases expression		 ISO
EXP		 Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CCL2 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of CCL2 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CCL2 protein]]; SIRT6 protein promotes the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CCL2 protein]]
Curcumin results in decreased expression of CCL2 mRNA
Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 mRNA]
Curcumin results in decreased expression of CCL2 mRNA; Curcumin results in decreased expression of CCL2 protein
Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]
Curcumin results in increased expression of CCL2 mRNA		 CTD PMID:10925121 PMID:11053056 PMID:17198877 PMID:17666914 PMID:18403477 More... NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of CCN2 mRNA; Curcumin results in decreased expression of CCN2 protein
IKBKB protein inhibits the reaction [Curcumin results in decreased expression of CCN2 mRNA]; Lipopolysaccharides inhibits the reaction [Curcumin results in decreased expression of CCN2 mRNA]; NFKBIA protein inhibits the reaction [Curcumin results in decreased expression of CCN2 mRNA]; PPARG protein promotes the reaction [Curcumin results in decreased expression of CCN2 mRNA]		 CTD PMID:17965732 PMID:19764552 NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581 		JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [bisphenol A results in increased expression of CCNA2 protein]
Curcumin results in decreased expression of CCNA2 protein		 CTD PMID:23222814 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Curcumin results in decreased expression of CCNB1 mRNA; Curcumin results in decreased expression of CCNB1 protein CTD PMID:17148446 PMID:18719366 PMID:19401701 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
decreases expression
increases degradation		 ISO
EXP		 [Curcumin co-treated with Isoflavones] results in decreased expression of CCND1 protein; calyculin A inhibits the reaction [Curcumin results in decreased expression of CCND1 protein]; Curcumin inhibits the reaction [Acrylamide results in increased expression of CCND1 protein]; Curcumin inhibits the reaction [Furazolidone results in increased expression of CCND1 protein]; Curcumin inhibits the reaction [Nicotine results in increased expression of CCND1 protein]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of CCND1 protein]; Curcumin inhibits the reaction [Sirolimus results in increased expression of CCND1 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of CCND1 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of CCND1 protein]; Curcumin inhibits the reaction [Trichloroethylene results in increased expression of CCND1 protein]; Curcumin inhibits the reaction [VIP protein results in increased expression of CCND1 protein]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of CCND1 protein]]; lactacystin inhibits the reaction [Curcumin results in increased degradation of CCND1 protein]; piperine inhibits the reaction [Curcumin results in decreased expression of CCND1 protein]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of CCND1 protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of CCND1 protein]
Curcumin results in increased expression of CCND1 mRNA
Curcumin results in decreased expression of CCND1 mRNA; Curcumin results in decreased expression of CCND1 protein
2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in decreased expression of CCND1 mRNA]; Buthionine Sulfoximine inhibits the reaction [Curcumin results in decreased expression of CCND1 protein]; Curcumin inhibits the reaction [bisphenol A results in decreased expression of CCND1 mRNA]
Curcumin results in decreased expression of CCND1; Curcumin results in decreased expression of CCND1 protein
[Curcumin co-treated with Gemcitabine] results in decreased expression of CCND1 protein
Curcumin analog results in decreased expression of CCND1 protein; Curcumin results in decreased expression of CCND1 mRNA; Curcumin results in decreased expression of CCND1 protein		 CTD PMID:15486348 PMID:15489888 PMID:15738001 PMID:16023083 PMID:16219905 More... NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Ccnd3 cyclin D3 multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [bisphenol A results in increased expression of CCND3 protein]
Curcumin results in decreased expression of CCND3 protein		 CTD PMID:23222814 NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616 		JBrowse link
G Ccne1 cyclin E1 decreases expression
multiple interactions
increases degradation		 ISO Curcumin results in decreased expression of CCNE1 protein
Curcumin results in decreased expression of CCNE1 mRNA
Curcumin inhibits the reaction [4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine results in increased expression of CCNE1 protein]; Curcumin inhibits the reaction [Sirolimus results in increased expression of CCNE1 protein]; lactacystin inhibits the reaction [Curcumin results in increased degradation of CCNE1 protein]		 CTD PMID:17148446 PMID:18156803 PMID:18299980 PMID:36640941 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959 		JBrowse link
G Ccpg1 cell cycle progression 1 increases expression ISO Curcumin results in increased expression of CCPG1 mRNA CTD PMID:17198877 NCBI chr 9:72,892,692...72,923,622
Ensembl chr 9:72,892,711...72,923,622 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 decreases expression EXP Curcumin results in decreased expression of CCR2 mRNA CTD PMID:18403477 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594 		JBrowse link
G Cd14 CD14 antigen multiple interactions ISO Curcumin inhibits the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased expression of CD14 protein]]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of CD14 protein] CTD PMID:18180316 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851 		JBrowse link
G Cd36 CD36 molecule decreases expression
increases expression
multiple interactions		 ISO
EXP		 Curcumin results in decreased expression of CD36 mRNA
Curcumin results in increased expression of CD36 mRNA
Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CD36 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 protein]
Curcumin results in decreased expression of CD36 mRNA; Curcumin results in decreased expression of CD36 protein		 CTD PMID:16713233 PMID:23386263 PMID:23603106 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G Cd40 CD40 antigen decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of CD40 mRNA
CD40 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL10 protein]]; CD40 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL6 protein]]; CD40 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of TNF protein]]; CD40 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]; CD40 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 protein]
[arsenic trioxide co-treated with Curcumin] results in increased expression of CD40 protein		 CTD PMID:16101141 PMID:27430728 PMID:35549587 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cd40lg CD40 ligand multiple interactions ISO [arsenic trioxide co-treated with Curcumin] results in increased expression of CD40LG protein CTD PMID:27430728 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402 		JBrowse link
G Cd44 CD44 antigen increases expression ISO Curcumin results in increased expression of CD44 mRNA CTD PMID:15713895 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010 		JBrowse link
G Cd47 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CD47 mRNA] CTD PMID:18200517 NCBI chr16:49,671,691...49,732,799
Ensembl chr16:49,620,896...49,735,373 		JBrowse link
G Cd55 CD55 molecule, decay accelerating factor for complement decreases expression ISO Curcumin results in decreased expression of CD55 mRNA CTD PMID:17999991 NCBI chr 1:130,357,526...130,390,513
Ensembl chr 1:130,366,764...130,390,481 		JBrowse link
G Cdc14b CDC14 cell division cycle 14B increases expression ISO Curcumin results in increased expression of CDC14B mRNA CTD PMID:17198877 NCBI chr13:64,337,085...64,423,670
Ensembl chr13:64,337,082...64,423,104 		JBrowse link
G Cdc20 cell division cycle 20 decreases expression ISO Curcumin results in decreased expression of CDC20 mRNA CTD PMID:22258452 NCBI chr 4:118,290,098...118,294,540
Ensembl chr 4:118,290,098...118,294,549 		JBrowse link
G Cdc25c cell division cycle 25C increases phosphorylation ISO Curcumin results in increased phosphorylation of CDC25C protein CTD PMID:19401701 NCBI chr18:34,866,046...34,884,644
Ensembl chr18:34,866,046...34,884,586 		JBrowse link
G Cdh1 cadherin 1 increases expression
multiple interactions		 ISO
EXP		 Curcumin results in increased expression of CDH1 protein
Curcumin inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of CDH1 mRNA]; Curcumin inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of CDH1 protein]
[Curcumin co-treated with Arsenic Trioxide] results in increased expression of CDH1 mRNA; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; Curcumin inhibits the reaction [Trichloroethylene results in decreased expression of CDH1 protein]		 CTD PMID:19573523 PMID:25656647 PMID:26191140 PMID:34233590 PMID:35487055 More... NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878 		JBrowse link
G Cdh11 cadherin 11 decreases expression ISO Curcumin results in decreased expression of CDH11 protein CTD PMID:18025290 NCBI chr 8:103,358,727...103,512,125
Ensembl chr 8:103,358,727...103,512,274 		JBrowse link
G Cdh17 cadherin 17 decreases expression ISO Curcumin results in decreased expression of CDH17 mRNA CTD PMID:17198877 NCBI chr 4:11,758,157...11,817,905
Ensembl chr 4:11,758,147...11,817,895 		JBrowse link
G Cdh2 cadherin 2 multiple interactions EXP
ISO		 Curcumin inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CDH2 mRNA]; Curcumin inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CDH2 protein]
Curcumin inhibits the reaction [Trichloroethylene results in increased expression of CDH2 protein]
Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of CDH2 protein]; ICAM1 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of CDH2 protein]]		 CTD PMID:26191140 PMID:34233590 PMID:35549587 NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303 		JBrowse link
G Cdk1 cyclin dependent kinase 1 decreases expression ISO Curcumin results in decreased expression of CDK1 mRNA
Curcumin results in decreased expression of CDK1 mRNA; Curcumin results in decreased expression of CDK1 protein		 CTD PMID:17148446 PMID:18299980 PMID:19401701 PMID:22258452 NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression
multiple interactions		 ISO
EXP		 Curcumin analog results in decreased expression of CDK2 mRNA; Curcumin results in decreased expression of CDK2 protein
Curcumin inhibits the reaction [bisphenol A results in increased expression of CDK2 protein]		 CTD PMID:19501152 PMID:23222814 PMID:26409325 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900 		JBrowse link
G Cdk4 cyclin dependent kinase 4 decreases expression ISO Curcumin analog results in decreased expression of CDK4 mRNA; Curcumin results in decreased expression of CDK4 protein CTD PMID:18156803 PMID:24211270 PMID:26409325 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789 		JBrowse link
G Cdk5 cyclin dependent kinase 5 decreases expression ISO Curcumin analog results in decreased expression of CDK5 mRNA CTD PMID:26409325 NCBI chr 5:24,612,595...24,628,737
Ensembl chr 5:24,623,239...24,628,528 		JBrowse link
G Cdk6 cyclin dependent kinase 6 decreases expression ISO Curcumin results in decreased expression of CDK6 protein CTD PMID:18156803 NCBI chr 5:3,391,004...3,581,008
Ensembl chr 5:3,391,485...3,581,008 		JBrowse link
G Cdk7 cyclin dependent kinase 7 decreases expression ISO Curcumin analog results in decreased expression of CDK7 mRNA CTD PMID:26409325 NCBI chr13:100,833,532...100,867,454
Ensembl chr13:100,839,139...100,867,447 		JBrowse link
G Cdk9 cyclin dependent kinase 9 decreases expression ISO Curcumin analog results in decreased expression of CDK9 mRNA CTD PMID:26409325 NCBI chr 2:32,595,794...32,608,098
Ensembl chr 2:32,595,796...32,603,088 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A multiple interactions
increases expression
decreases expression		 ISO
EXP		 [Arsenic Trioxide co-treated with Curcumin] results in increased expression of CDKN1A protein; [bicalutamide co-treated with Curcumin co-treated with Quercetin] results in increased expression of CDKN1A protein; [Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of CDKN1A mRNA; [Curcumin co-treated with Quercetin] results in increased expression of CDKN1A protein; [piperine co-treated with Curcumin] results in decreased expression of CDKN1A protein; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CDKN1A protein]; Curcumin inhibits the reaction [bisphenol A results in decreased expression of CDKN1A protein]; Dihydrotestosterone inhibits the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CDKN1A protein]; EGR1 protein affects the reaction [Curcumin results in increased expression of CDKN1A protein]; EGR1 protein promotes the reaction [Curcumin results in increased expression of CDKN1A mRNA]; MAPK1 protein affects the reaction [Curcumin results in increased expression of CDKN1A mRNA]; MAPK8 protein affects the reaction [Curcumin results in increased expression of CDKN1A mRNA]; TNFSF10 protein promotes the reaction [Curcumin results in increased expression of CDKN1A protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of CDKN1A protein]
[Curcumin co-treated with Quercetin] inhibits the reaction [Benzo(a)pyrene results in decreased expression of CDKN1A protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in decreased expression of CDKN1A protein]
Curcumin results in increased expression of CDKN1A; Curcumin results in increased expression of CDKN1A mRNA; Curcumin results in increased expression of CDKN1A protein
[Curcumin results in decreased expression of MDM2 protein] which results in decreased expression of CDKN1A mRNA; Curcumin results in decreased expression of CDKN1A protein
Buthionine Sulfoximine inhibits the reaction [Curcumin results in increased expression of CDKN1A protein]		 CTD PMID:15713895 PMID:15738001 PMID:17148446 PMID:17332326 PMID:17602960 More... NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B increases expression
multiple interactions
decreases expression		 ISO
EXP		 Curcumin results in increased expression of CDKN1B mRNA; Curcumin results in increased expression of CDKN1B protein
Buthionine Sulfoximine inhibits the reaction [Curcumin results in increased expression of CDKN1B protein]
[Arsenic Trioxide co-treated with Curcumin] results in increased expression of CDKN1B protein; [Curcumin co-treated with Arsenic Trioxide] results in increased expression of CDKN1B protein; [Curcumin co-treated with Quercetin] results in increased expression of CDKN1B protein; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CDKN1B protein]; Dihydrotestosterone inhibits the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CDKN1B protein]; TNFSF10 protein promotes the reaction [Curcumin results in increased expression of CDKN1B protein]
Curcumin results in decreased expression of CDKN1B protein		 CTD PMID:15713895 PMID:17602960 PMID:18156803 PMID:18226269 PMID:18593936 More... NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476 		JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A decreases expression
increases expression		 ISO Curcumin results in decreased expression of CDKN2A protein
Curcumin results in increased expression of CDKN2A protein		 CTD PMID:17148446 PMID:18156803 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890 		JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D decreases expression ISO Curcumin results in decreased expression of CDKN2D mRNA CTD PMID:18299980 NCBI chr 9:21,199,759...21,202,553
Ensembl chr 9:21,199,706...21,202,703 		JBrowse link
G Cdx2 caudal type homeobox 2 increases expression ISO
EXP		 Curcumin results in increased expression of CDX2 mRNA CTD PMID:18299980 PMID:27237783 NCBI chr 5:147,237,710...147,244,059
Ensembl chr 5:147,237,615...147,244,080 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions EXP Curcumin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]]; Curcumin inhibits the reaction [Dietary Fats results in increased expression of CEBPA mRNA] CTD PMID:19297423 PMID:28595985 NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CEBPB mRNA] CTD PMID:18200517 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338 		JBrowse link
G Ces1d carboxylesterase 1D multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES1 mRNA] CTD PMID:18200517 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466 		JBrowse link
G Ces3b carboxylesterase 3B multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES3 mRNA] CTD PMID:18200517 NCBI chr 8:105,810,365...105,820,561
Ensembl chr 8:105,810,385...105,820,561 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of CFLAR mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of CFLAR mRNA]
Curcumin results in decreased expression of CFLAR protein		 CTD PMID:16173963 PMID:16219905 PMID:23452621 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043 		JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator multiple interactions
affects localization
increases activity		 ISO
EXP		 [PRKCA protein results in increased phosphorylation of CFTR protein] promotes the reaction [Curcumin results in increased activity of CFTR protein]; Adenosine Triphosphate affects the reaction [Curcumin results in increased activity of CFTR protein mutant form]; Curcumin analog inhibits the reaction [CFTR protein results in increased export of Hyaluronic Acid]
Curcumin affects the folding of and affects the localization of CFTR protein mutant form
Curcumin affects the localization of CFTR protein mutant form
Curcumin results in increased activity of CFTR protein; Curcumin results in increased activity of CFTR protein mutant form		 CTD PMID:15105504 PMID:15280357 PMID:15582996 PMID:17178710 PMID:23978416 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767 		JBrowse link
G Chat choline acetyltransferase multiple interactions ISO Curcumin inhibits the reaction [sodium arsenite results in decreased expression of CHAT protein] CTD PMID:21839772 NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946 		JBrowse link
G Chek1 checkpoint kinase 1 decreases response to substance
multiple interactions
increases activity
increases phosphorylation		 ISO CHEK1 protein results in decreased susceptibility to Curcumin
Curcumin inhibits the reaction [Furazolidone results in increased expression of CHEK1 protein]
Curcumin results in increased activity of CHEK1 protein
Curcumin results in increased phosphorylation of CHEK1 protein		 CTD PMID:18602917 PMID:19401701 PMID:27996348 NCBI chr 9:36,619,935...36,637,897
Ensembl chr 9:36,619,778...36,638,361 		JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions
increases phosphorylation		 ISO [Curcumin co-treated with Dihydrotestosterone] results in increased phosphorylation of CHEK2 protein; [Curcumin co-treated with Metribolone] results in increased phosphorylation of CHEK2 protein; [Isoflavones co-treated with Curcumin] results in increased phosphorylation of CHEK2 protein; Flutamide inhibits the reaction [[Dihydrotestosterone co-treated with Curcumin] results in increased phosphorylation of CHEK2 protein]
Curcumin results in increased phosphorylation of CHEK2 protein		 CTD PMID:21134073 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011 		JBrowse link
G Chil3 chitinase-like 3 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CHIL3 mRNA] CTD PMID:18200517 NCBI chr 3:106,054,870...106,074,852
Ensembl chr 3:106,054,870...106,074,880 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2, cardiac multiple interactions ISO Curcumin inhibits the reaction [sodium arsenite results in decreased expression of CHRM2 mRNA] CTD PMID:24952339 NCBI chr 6:36,364,928...36,505,573
Ensembl chr 6:36,365,019...36,505,349 		JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase multiple interactions
decreases activity		 ISO Curcumin inhibits the reaction [TNF protein results in increased activity of CHUK protein]; Curcumin inhibits the reaction [TNFSF11 protein results in increased activity of CHUK protein]
Curcumin results in decreased activity of CHUK protein		 CTD PMID:15129424 PMID:15489888 PMID:16023083 PMID:16219905 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919 		JBrowse link
G Ckb creatine kinase, brain multiple interactions ISO Curcumin inhibits the reaction [Doxorubicin results in increased expression of [CKM protein binds to CKB protein]]; Curcumin inhibits the reaction [lead acetate results in increased secretion of [CKM protein binds to CKB protein]] CTD PMID:21378372 PMID:29315967 NCBI chr12:111,635,789...111,638,772
Ensembl chr12:111,635,795...111,638,772 		JBrowse link
G Ckm creatine kinase, muscle multiple interactions ISO Curcumin inhibits the reaction [Doxorubicin results in increased expression of [CKM protein binds to CKB protein]]; Curcumin inhibits the reaction [lead acetate results in increased secretion of [CKM protein binds to CKB protein]] CTD PMID:21378372 PMID:29315967 NCBI chr 7:19,145,019...19,155,508
Ensembl chr 7:19,138,701...19,156,766 		JBrowse link
G Clca4a chloride channel accessory 4A multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CLCA4A mRNA] CTD PMID:18200517 NCBI chr 3:144,658,247...144,680,806
Ensembl chr 3:144,658,241...144,680,806 		JBrowse link
G Clcn6 chloride channel, voltage-sensitive 6 decreases expression ISO Curcumin results in decreased expression of CLCN6 mRNA CTD PMID:17198877 NCBI chr 4:148,088,716...148,123,270
Ensembl chr 4:148,088,716...148,123,278 		JBrowse link
G Cldn1 claudin 1 multiple interactions EXP Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein] CTD PMID:35817260 NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591 		JBrowse link
G Cldn2 claudin 2 multiple interactions ISO Curcumin inhibits the reaction [maleic acid results in decreased expression of CLDN2] CTD PMID:25119790 NCBI chr  X:138,701,552...138,712,135
Ensembl chr  X:138,701,577...138,712,135 		JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions
decreases expression		 ISO
EXP		 Buthionine Sulfoximine inhibits the reaction [Curcumin results in decreased expression of COL1A1 mRNA]; Buthionine Sulfoximine inhibits the reaction [Curcumin results in decreased expression of COL1A1 protein]; Curcumin analog inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]]
Curcumin analog inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]
Curcumin results in decreased expression of COL1A1 mRNA; Curcumin results in decreased expression of COL1A1 protein		 CTD PMID:17355460 PMID:17434272 PMID:17531121 PMID:17602960 PMID:17965732 More... NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868 		JBrowse link
G Col1a2 collagen, type I, alpha 2 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A2 mRNA] CTD PMID:18200517 NCBI chr 6:4,505,618...4,541,543
Ensembl chr 6:4,504,814...4,541,544 		JBrowse link
G Col27a1 collagen, type XXVII, alpha 1 increases expression ISO Curcumin results in increased expression of COL27A1 mRNA CTD PMID:18299980 NCBI chr 4:63,132,246...63,253,228
Ensembl chr 4:63,132,241...63,253,228 		JBrowse link
G Col2a1 collagen, type II, alpha 1 increases expression
multiple interactions		 ISO Curcumin results in increased expression of COL2A1 mRNA; Curcumin results in increased expression of COL2A1 protein
[resveratrol co-treated with Curcumin] results in increased expression of COL2A1 protein		 CTD PMID:18321735 PMID:19889203 NCBI chr15:97,873,483...97,902,525
Ensembl chr15:97,873,483...97,902,576 		JBrowse link
G Col3a1 collagen, type III, alpha 1 multiple interactions ISO Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA] CTD PMID:22683883 NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866 		JBrowse link
G Col4a1 collagen, type IV, alpha 1 increases expression
multiple interactions		 ISO
EXP		 Curcumin results in increased expression of COL4A1 mRNA
Curcumin analog inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A1 mRNA]		 CTD PMID:18200517 PMID:21594647 PMID:28700904 NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826 		JBrowse link
G Col4a2 collagen, type IV, alpha 2 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL4A2 mRNA] CTD PMID:18200517 NCBI chr 8:11,362,878...11,499,287
Ensembl chr 8:11,362,805...11,499,287 		JBrowse link
G Col4a5 collagen, type IV, alpha 5 decreases expression ISO Curcumin results in decreased expression of COL4A5 mRNA CTD PMID:15713895 NCBI chr  X:140,258,367...140,472,232
Ensembl chr  X:140,258,381...140,472,230 		JBrowse link
G Col5a1 collagen, type V, alpha 1 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A1 mRNA] CTD PMID:18200517 NCBI chr 2:27,776,393...27,929,522
Ensembl chr 2:27,776,437...27,929,526 		JBrowse link
G Col5a2 collagen, type V, alpha 2 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL5A2 mRNA] CTD PMID:18200517 NCBI chr 1:45,413,491...45,542,442
Ensembl chr 1:45,413,481...45,542,442 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver increases expression EXP Curcumin results in increased expression of CPT1A mRNA CTD PMID:19297423 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression
multiple interactions
increases phosphorylation		 ISO
EXP		 Curcumin results in increased expression of CREB1 mRNA
1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one inhibits the reaction [Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of CREB1 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of CREB1 protein]]; Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of CREB1 protein]
[Docosahexaenoic Acids co-treated with Curcumin] results in increased expression of CREB1 mRNA; Curcumin inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CREB1 protein]
Curcumin results in increased phosphorylation of CREB1 protein		 CTD PMID:17022948 PMID:18299980 PMID:22911773 PMID:27966075 PMID:29723552 More... NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707 		JBrowse link
G Creb3 cAMP responsive element binding protein 3 increases expression ISO Curcumin results in increased expression of CREB3 mRNA CTD PMID:18299980 NCBI chr 4:43,562,658...43,567,061
Ensembl chr 4:43,562,332...43,567,060 		JBrowse link
G Crebbp CREB binding protein multiple interactions ISO Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [CREBBP protein binds to KLK3 enhancer]] CTD PMID:22258452 NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861 		JBrowse link
G Crp C-reactive protein, pentraxin-related multiple interactions ISO
EXP		 Curcumin analog inhibits the reaction [Copper Sulfate results in increased secretion of CRP protein]; Curcumin inhibits the reaction [Copper Sulfate results in increased secretion of CRP protein]; Curcumin inhibits the reaction [Fructose results in increased expression of CRP protein]; Curcumin inhibits the reaction [lead acetate results in increased secretion of CRP protein]
[Curcumin co-treated with Niacin co-treated with ZM 241385] inhibits the reaction [Rotenone results in increased expression of CRP protein]; Curcumin inhibits the reaction [Rotenone results in increased expression of CRP protein]		 CTD PMID:21378372 PMID:26713546 PMID:30431687 PMID:31820278 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Cryab crystallin, alpha B multiple interactions EXP
ISO		 Curcumin promotes the reaction [arsenite results in increased expression of CRYAB protein]
[Curcumin co-treated with arsenite] results in increased expression of CRYAB mRNA; [Curcumin co-treated with Cadmium Chloride] results in increased expression of CRYAB protein; Curcumin promotes the reaction [arsenite results in increased expression of CRYAB protein]		 CTD PMID:9764755 NCBI chr 9:50,657,251...50,667,936
Ensembl chr 9:50,662,625...50,667,936 		JBrowse link
G Cs citrate synthase affects expression ISO Curcumin affects the expression of CS mRNA CTD PMID:18539377 NCBI chr10:128,173,596...128,198,351
Ensembl chr10:128,173,603...128,198,348 		JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) multiple interactions ISO Curcumin inhibits the reaction [CSF1 protein results in increased phosphorylation of CSF1R protein] CTD PMID:15129424 NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785 		JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions
increases expression		 ISO
EXP		 Curcumin inhibits the reaction [CSF1 protein results in increased phosphorylation of CSF1R protein]
Curcumin results in increased expression of CSF1R mRNA		 CTD PMID:15129424 PMID:22714040 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221 		JBrowse link
G Csf2ra colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) increases expression EXP Curcumin results in increased expression of CSF2RA mRNA CTD PMID:22714040 NCBI chr19:61,205,629...61,221,141
Ensembl chr19:61,212,395...61,216,867 		JBrowse link
G Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CSF2RB mRNA] CTD PMID:18200517 NCBI chr15:78,166,707...78,189,921
Ensembl chr15:78,166,707...78,189,921 		JBrowse link
G Csprs component of Sp100-rs decreases expression EXP Curcumin results in decreased expression of CSPRS mRNA CTD PMID:19555370
G Ctla2a cytotoxic T lymphocyte-associated protein 2 alpha multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTLA2A mRNA] CTD PMID:18200517 NCBI chr13:61,081,969...61,084,439
Ensembl chr13:61,081,969...61,084,439 		JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
increases expression
multiple interactions
decreases phosphorylation
increases degradation		 ISO
EXP		 Curcumin analog results in decreased expression of CTNNB1 mRNA; Curcumin results in decreased expression of CTNNB1 mRNA; Curcumin results in decreased expression of CTNNB1 protein
Curcumin results in increased expression of CTNNB1 mRNA
Curcumin inhibits the reaction [bisphenol A results in decreased expression of CTNNB1 mRNA]; Curcumin results in decreased phosphorylation of and affects the localization of CTNNB1 protein
Curcumin results in decreased phosphorylation of CTNNB1 protein
[piperine co-treated with Curcumin] results in decreased expression of CTNNB1 protein; Curcumin inhibits the reaction [CTNNB1 protein binds to TCF7L2 protein]; Curcumin inhibits the reaction [IL1B protein results in increased expression of CTNNB1 protein]; Curcumin results in decreased activity of [CTNNB1 protein binds to TCF7L2 protein]; Vitamin E inhibits the reaction [Curcumin results in decreased expression of CTNNB1 protein]
Curcumin analog results in increased degradation of CTNNB1 protein; Curcumin results in increased degradation of CTNNB1 protein		 CTD PMID:10783313 PMID:17041101 PMID:19294764 PMID:19573523 PMID:25963729 More... NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573 		JBrowse link
G Ctsb cathepsin B multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]
Curcumin analog results in decreased expression of CTSB mRNA		 CTD PMID:8534267 PMID:26409325 NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372 		JBrowse link
G Ctsd cathepsin D multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; Curcumin inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]
Curcumin analog results in decreased expression of CTSD mRNA		 CTD PMID:8534267 PMID:26409325 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775 		JBrowse link
G Ctsl cathepsin L decreases expression ISO Curcumin results in decreased expression of CTSL protein CTD PMID:34138966 NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704 		JBrowse link
G Ctss cathepsin S decreases expression EXP Curcumin results in decreased expression of CTSS mRNA CTD PMID:19555370 NCBI chr 3:95,434,097...95,463,716
Ensembl chr 3:95,434,097...95,463,714 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions
decreases expression		 ISO NFKBIA protein affects the reaction [Curcumin results in decreased expression of CXCL1 mRNA]
Curcumin results in decreased expression of CXCL1 mRNA; Curcumin results in decreased expression of CXCL1 protein		 CTD PMID:17999991 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions ISO Curcumin inhibits the reaction [CXCL12 protein results in increased expression of CXCR4 mRNA]; Curcumin inhibits the reaction [CXCL12 protein results in increased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [CXCL12 protein results in increased phosphorylation of NOS3 protein] CTD PMID:18660423 NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression EXP Curcumin results in decreased expression of CXCL14 mRNA CTD PMID:19555370 NCBI chr13:56,436,456...56,444,624
Ensembl chr13:56,436,456...56,444,364 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of CXCL8 protein
Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [Acetylmuramyl-Alanyl-Isoglutamine results in increased expression of and results in increased secretion of CXCL8 protein]; Curcumin inhibits the reaction [Acids results in increased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [Acids results in increased secretion of CXCL8 protein]; Curcumin inhibits the reaction [cadmium sulfate results in increased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [cadmium sulfate results in increased secretion of CXCL8 protein]; Curcumin inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [lauric acid results in increased expression of and results in increased secretion of CXCL8 protein]; Curcumin inhibits the reaction [Neurotensin results in increased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [Neurotensin results in increased expression of CXCL8 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [Shiga Toxin results in increased expression of CXCL8 protein]; Curcumin inhibits the reaction [Sodium Fluoride results in increased secretion of CXCL8 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of CXCL8 protein]; Curcumin inhibits the reaction [TNF protein results in decreased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; Curcumin results in decreased expression of and results in decreased secretion of CXCL8 protein; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of CXCL8 protein]		 CTD PMID:12216086 PMID:16819191 PMID:17000667 PMID:17151092 PMID:17273796 More... NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 decreases expression
multiple interactions		 ISO
EXP		 Curcumin results in decreased expression of CXCL2 mRNA; Curcumin results in decreased expression of CXCL2 protein
Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CXCL2 mRNA]
Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased secretion of CXCL2 protein]
NFKBIA protein affects the reaction [Curcumin results in decreased expression of CXCL2 mRNA]		 CTD PMID:17999991 PMID:18001810 PMID:18200517 PMID:27194111 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression
multiple interactions		 ISO
EXP		 Curcumin results in decreased expression of CXCL1 mRNA; Curcumin results in decreased expression of CXCL1 protein
Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL1 mRNA]; Curcumin inhibits the reaction [Fluorouracil results in increased expression of CXCL1 protein]
NFKBIA protein affects the reaction [Curcumin results in decreased expression of CXCL1 mRNA]		 CTD PMID:17999991 PMID:27194111 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 increases expression ISO Curcumin results in increased expression of CXCR1 protein CTD PMID:12216086 NCBI chr 1:74,228,862...74,233,867
Ensembl chr 1:74,230,944...74,233,790 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 increases expression ISO Curcumin results in increased expression of CXCR2 protein CTD PMID:12216086 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of CXCR4 mRNA
Curcumin inhibits the reaction [CXCL12 protein results in increased expression of CXCR4 mRNA]		 CTD PMID:17198877 PMID:18660423 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030 		JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions		 ISO Curcumin affects the localization of CYCS protein
[Arsenic Trioxide co-treated with Curcumin] results in increased expression of CYCS protein; [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] which results in increased expression of CYCS protein		 CTD PMID:19235267 PMID:27430728 PMID:33617879 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases expression
decreases activity
increases expression
increases activity		 ISO
EXP		 Acetylcysteine affects the reaction [Curcumin affects the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]]; Buthionine Sulfoximine affects the reaction [Curcumin affects the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]]; Curcumin affects the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]; Curcumin affects the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1A1 mRNA]; Curcumin inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]; Curcumin promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1A1 mRNA]; decitabine affects the reaction [Curcumin affects the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1A1 mRNA]]; trichostatin A affects the reaction [Curcumin affects the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1A1 mRNA]]
Curcumin inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
Curcumin results in decreased expression of CYP1A1 mRNA
Curcumin results in decreased activity of CYP1A1 protein
Curcumin results in increased expression of CYP1A1 mRNA
Curcumin results in increased activity of CYP1A1 protein
Curcumin inhibits the reaction [Aflatoxin B1 results in increased activity of CYP1A1 protein]; Curcumin inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Curcumin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP1A1 protein]; Curcumin inhibits the reaction [Fenitrothion results in increased expression of CYP1A1 mRNA]		 CTD PMID:11454723 PMID:12628514 PMID:15841493 PMID:16288784 PMID:17012224 More... NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
multiple interactions		 ISO
EXP		 Curcumin results in decreased activity of CYP1A2 protein
Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of CYP1A2 mRNA]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]
Curcumin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP1A2 protein]; Curcumin inhibits the reaction [Fenitrothion results in increased expression of CYP1A2 mRNA]		 CTD PMID:15841493 PMID:16288784 PMID:18321868 PMID:34802538 PMID:35063475 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]
Curcumin results in decreased expression of CYP1B1 mRNA		 CTD PMID:17637178 PMID:19018768 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO [Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of CYP24A1 mRNA
Curcumin results in increased expression of CYP24A1 protein		 CTD PMID:20153625 NCBI chr 2:170,324,877...170,339,065
Ensembl chr 2:170,324,628...170,339,065 		JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 decreases expression ISO Curcumin results in decreased expression of CYP2D6 mRNA CTD PMID:33582110 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects expression
multiple interactions
increases expression		 ISO
EXP		 Curcumin affects the expression of CYP2E1 protein
Curcumin inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA]
Curcumin inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA]; Curcumin inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein]; Curcumin metabolite inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA]; Curcumin metabolite inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein]; Curcumin metabolite promotes the reaction [Acetaminophen results in decreased activity of CYP2E1 protein]
Curcumin inhibits the reaction [Acrylamide results in increased expression of CYP2E1 protein]
Curcumin results in increased expression of CYP2E1 mRNA		 CTD PMID:16805852 PMID:18539377 PMID:24508477 PMID:30423402 PMID:33350580 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 multiple interactions EXP Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of CYP3A11 mRNA] CTD PMID:35063475 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyth4 cytohesin 4 increases expression ISO Curcumin results in increased expression of CYTH4 mRNA CTD PMID:17198877 NCBI chr15:78,481,247...78,506,219
Ensembl chr15:78,481,247...78,506,219 		JBrowse link
G Daxx Fas death domain-associated protein increases expression ISO Curcumin results in increased expression of DAXX mRNA CTD PMID:16101141 NCBI chr17:34,128,379...34,134,564
Ensembl chr17:34,128,388...34,134,564 		JBrowse link
G Dbn1 drebrin 1 multiple interactions ISO Curcumin inhibits the reaction [Glucose results in decreased expression of DBN1 mRNA] CTD PMID:23333261 NCBI chr13:55,621,241...55,635,874
Ensembl chr13:55,621,242...55,635,924 		JBrowse link
G Dcn decorin increases expression ISO Curcumin results in increased expression of DCN mRNA CTD PMID:21594647 NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005 		JBrowse link
G Dcx doublecortin multiple interactions
increases expression		 ISO
EXP		 Curcumin inhibits the reaction [bisphenol A results in decreased expression of DCX mRNA]
Curcumin inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DCX protein]
Curcumin results in increased expression of DCX mRNA		 CTD PMID:25963729 PMID:32735850 NCBI chr  X:142,638,838...142,716,392
Ensembl chr  X:142,638,838...142,716,307 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression		 ISO
EXP		 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA]; Buthionine Sulfoximine promotes the reaction [Curcumin results in increased expression of DDIT3 mRNA]; Buthionine Sulfoximine promotes the reaction [Curcumin results in increased expression of DDIT3 protein]; Curcumin inhibits the reaction [Furazolidone results in increased expression of DDIT3 protein]; Glutathione inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA]; Glutathione inhibits the reaction [Curcumin results in increased expression of DDIT3 protein]; PRKCD protein promotes the reaction [Curcumin results in increased expression of DDIT3 mRNA]; rottlerin inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA]; Wortmannin inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA]; Wortmannin inhibits the reaction [Curcumin results in increased expression of DDIT3 protein]
Curcumin results in increased expression of DDIT3 mRNA; Curcumin results in increased expression of DDIT3 protein		 CTD PMID:16613838 PMID:17171638 PMID:18200517 PMID:18719366 PMID:21793155 More... NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like decreases expression
increases expression		 ISO Curcumin results in decreased expression of DDIT4L mRNA
Curcumin results in increased expression of DDIT4L mRNA		 CTD PMID:17999991 PMID:18299980 NCBI chr 3:137,329,433...137,334,093
Ensembl chr 3:137,327,373...137,334,094 		JBrowse link
G Dffb DNA fragmentation factor, beta subunit increases expression
decreases expression		 EXP Curcumin results in increased expression of DFFB mRNA; Curcumin results in increased expression of DFFB protein
Curcumin results in decreased expression of DFFB protein		 CTD PMID:21397623 PMID:22714040 NCBI chr 4:154,048,904...154,059,578
Ensembl chr 4:154,048,906...154,059,583 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression
affects expression		 ISO
EXP		 Curcumin results in decreased expression of DHCR24 mRNA
Curcumin affects the expression of DHCR24 mRNA		 CTD PMID:27208389 NCBI chr 4:106,418,279...106,446,310
Ensembl chr 4:106,418,235...106,446,310 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase affects expression
decreases expression		 EXP
ISO		 Curcumin affects the expression of DHCR7 mRNA
Curcumin results in decreased expression of DHCR7 mRNA		 CTD PMID:27208389 NCBI chr 7:143,376,827...143,402,147
Ensembl chr 7:143,376,882...143,402,147 		JBrowse link
G Dhrs1 dehydrogenase/reductase 1 decreases expression ISO Curcumin results in decreased expression of DHRS1 mRNA CTD PMID:17198877 NCBI chr14:55,976,477...55,983,147
Ensembl chr14:55,976,477...55,983,147 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein affects localization
multiple interactions
increases expression
increases response to substance		 EXP
ISO		 Curcumin affects the localization of DIABLO protein
[arsenic trioxide co-treated with Curcumin] results in increased expression of DIABLO protein
Curcumin results in increased expression of DIABLO mRNA
DIABLO protein results in increased susceptibility to Curcumin		 CTD PMID:17277231 PMID:23555722 PMID:27430728 NCBI chr 5:123,649,393...123,664,825
Ensembl chr 5:123,647,828...123,662,239 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of DKK1 mRNA; Curcumin results in decreased expression of DKK1 protein
Curcumin inhibits the reaction [bisphenol A results in increased expression of DKK1 mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased expression of DKK1 protein]		 CTD PMID:25963729 NCBI chr19:30,523,276...30,526,896
Ensembl chr19:30,523,263...30,527,065 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions ISO Curcumin inhibits the reaction [sodium arsenite results in decreased expression of DLG4 protein] CTD PMID:29723552 NCBI chr11:69,908,029...69,938,107
Ensembl chr11:69,907,768...69,938,348 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Curcumin results in increased expression of DNAJB9 mRNA CTD PMID:17999991 NCBI chr12:44,252,680...44,256,851
Ensembl chr12:44,252,342...44,257,109 		JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO Curcumin inhibits the reaction [Potassium Dichromate results in increased expression of DNM1L protein] CTD PMID:32980475 NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823 		JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression
affects expression
increases activity
multiple interactions		 ISO
EXP		 Curcumin results in decreased expression of DNMT1 mRNA; Curcumin results in decreased expression of DNMT1 protein
Curcumin analog affects the expression of DNMT1 protein
Curcumin results in increased activity of DNMT1 protein
Curcumin promotes the reaction [Quercetin results in increased activity of DNMT1 protein]; Quercetin promotes the reaction [Curcumin results in increased activity of DNMT1 protein]
Curcumin analog results in decreased expression of DNMT1 protein		 CTD PMID:23593078 PMID:26991801 PMID:27132804 PMID:29228771 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184 		JBrowse link
G Dnmt3a DNA methyltransferase 3A decreases expression ISO
EXP		 Curcumin results in decreased expression of DNMT3A mRNA
Curcumin analog results in decreased expression of DNMT3A protein		 CTD PMID:23593078 PMID:26991801 PMID:29228771 NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443 		JBrowse link
G Dnmt3b DNA methyltransferase 3B decreases expression ISO
EXP		 Curcumin results in decreased expression of DNMT3B mRNA
Curcumin analog results in decreased expression of DNMT3B protein		 CTD PMID:23593078 PMID:26991801 PMID:29228771 NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650 		JBrowse link
G Dram1 DNA-damage regulated autophagy modulator 1 increases expression ISO Curcumin results in increased expression of DRAM1 mRNA CTD PMID:21594647 NCBI chr10:88,158,663...88,200,218
Ensembl chr10:88,158,666...88,214,942 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO Curcumin inhibits the reaction [sodium arsenite results in decreased expression of DRD2 protein] CTD PMID:27966075 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression
multiple interactions		 ISO Curcumin results in increased expression of DUSP1 mRNA
Curcumin promotes the reaction [Lipopolysaccharides results in increased phosphorylation of DUSP1 protein]		 CTD PMID:15713895 PMID:20885979 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102 		JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO Curcumin results in increased expression of DUSP10 mRNA CTD PMID:15713895 PMID:17151092 NCBI chr 1:183,766,575...183,807,833
Ensembl chr 1:183,745,499...183,807,833 		JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression ISO Curcumin results in increased expression of DUSP5 mRNA CTD PMID:17198877 NCBI chr19:53,517,576...53,530,240
Ensembl chr19:53,517,540...53,530,862 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 decreases expression
increases expression
multiple interactions		 ISO Curcumin results in decreased expression of DVL1 protein
Curcumin results in increased expression of DVL1 mRNA; Curcumin results in increased expression of DVL1 protein
Curcumin inhibits the reaction [bisphenol A results in decreased expression of DVL1 mRNA]; Curcumin inhibits the reaction [bisphenol A results in decreased expression of DVL1 protein]		 CTD PMID:19573523 PMID:25963729 NCBI chr 4:155,931,829...155,943,760
Ensembl chr 4:155,931,859...155,943,760 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 increases expression ISO Curcumin results in increased expression of DYNLL1 mRNA CTD PMID:17198877 NCBI chr 5:115,435,129...115,438,995
Ensembl chr 5:115,435,169...115,439,058 		JBrowse link
G Dyrk2 dual-specificity tyrosine phosphorylation regulated kinase 2 decreases activity
multiple interactions		 ISO Curcumin results in decreased activity of DYRK2 protein
[Curcumin binds to 4-nitrobenzaldehyde] which results in decreased activity of DYRK2 protein		 CTD PMID:33617879 NCBI chr10:118,691,507...118,725,144
Ensembl chr10:118,691,508...118,706,114 		JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO Curcumin results in decreased expression of E2F1 mRNA CTD PMID:18299980 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812 		JBrowse link
G E2f5 E2F transcription factor 5 decreases expression ISO Curcumin results in decreased expression of E2F5 mRNA CTD PMID:15713895 NCBI chr 3:14,638,370...14,671,369
Ensembl chr 3:14,643,701...14,671,369 		JBrowse link
G Ech1 enoyl coenzyme A hydratase 1, peroxisomal increases expression ISO Curcumin results in increased expression of ECH1 mRNA CTD PMID:18539377 NCBI chr 7:28,524,763...28,531,664
Ensembl chr 7:28,524,642...28,531,672 		JBrowse link
G Edaradd EDAR associated via death domain multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of EDARADD mRNA] CTD PMID:23452621 NCBI chr13:12,486,090...12,535,413
Ensembl chr13:12,487,513...12,535,319 		JBrowse link
G Edil3 EGF-like repeats and discoidin I-like domains 3 decreases expression ISO Curcumin results in decreased expression of EDIL3 mRNA CTD PMID:18421014 NCBI chr13:88,969,591...89,471,344
Ensembl chr13:88,969,591...89,471,342 		JBrowse link
G Egf epidermal growth factor decreases activity
multiple interactions		 ISO Curcumin results in decreased activity of EGF protein
Curcumin inhibits the reaction [EGF protein results in decreased expression of PPARG mRNA]; Curcumin inhibits the reaction [EGF protein results in decreased expression of PPARG protein]
Curcumin inhibits the reaction [EGF protein results in increased expression of AQP3 protein]; Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [EGF protein results in increased secretion of PTHLH protein]		 CTD PMID:10851300 PMID:15129424 PMID:15486348 PMID:17372590 PMID:18214481 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases phosphorylation
decreases expression		 ISO Curcumin inhibits the reaction [Acrylamide results in increased expression of EGFR protein]; Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; Curcumin promotes the reaction [Folfox protocol results in decreased expression of EGFR protein]; Curcumin promotes the reaction [Folfox protocol results in decreased phosphorylation of and results in decreased activity of EGFR protein]; Curcumin results in decreased expression of and results in decreased activity of EGFR protein; Curcumin results in decreased phosphorylation of and results in decreased activity of EGFR protein; Fluorouracil promotes the reaction [Curcumin results in decreased expression of EGFR protein]; Fluorouracil promotes the reaction [Curcumin results in decreased phosphorylation of and results in decreased activity of EGFR protein]
Curcumin results in decreased phosphorylation of EGFR protein
Curcumin results in decreased expression of EGFR mRNA; Curcumin results in decreased expression of EGFR protein
Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of EGFR mRNA]
Curcumin analog results in decreased expression of EGFR mRNA; Curcumin results in decreased expression of EGFR mRNA; Curcumin results in decreased expression of EGFR protein		 CTD PMID:10851300 PMID:15129424 PMID:15486348 PMID:17372590 PMID:17918158 More... NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression
decreases expression		 ISO EGR1 protein affects the reaction [Curcumin results in increased expression of CDKN1A protein]; EGR1 protein promotes the reaction [Curcumin results in increased expression of CDKN1A mRNA]; pyrazolanthrone inhibits the reaction [Curcumin results in increased expression of EGR1 protein]; U 0126 inhibits the reaction [Curcumin results in increased expression of EGR1 protein]
Curcumin results in increased expression of EGR1 mRNA; Curcumin results in increased expression of EGR1 protein
Curcumin results in decreased expression of EGR1 mRNA		 CTD PMID:17198877 PMID:17999991 PMID:18316600 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037 		JBrowse link
G Eif1 eukaryotic translation initiation factor 1 decreases expression ISO Curcumin results in decreased expression of EIF1 mRNA CTD PMID:17999991 NCBI chr11:100,210,775...100,212,925
Ensembl chr11:100,210,711...100,212,922 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
decreases expression
decreases phosphorylation		 ISO calyculin A inhibits the reaction [Curcumin results in decreased phosphorylation of EIF4EBP1 protein]; Curcumin inhibits the reaction [bisphenol A results in increased expression of EIF4EBP1 protein]
Curcumin results in decreased expression of EIF4EBP1 protein		 CTD PMID:18790744 PMID:23222814 PMID:34634291 NCBI chr 8:27,750,355...27,765,684
Ensembl chr 8:27,750,357...27,766,702 		JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4, gamma 1 decreases phosphorylation ISO Curcumin results in decreased phosphorylation of EIF4G1 protein CTD PMID:18790744 NCBI chr16:20,491,457...20,511,633
Ensembl chr16:20,487,063...20,511,634 		JBrowse link
G Elf2 E74-like factor 2 decreases expression ISO Curcumin results in decreased expression of ELF2 mRNA CTD PMID:15713895 NCBI chr 3:51,160,141...51,248,101
Ensembl chr 3:51,160,141...51,248,084 		JBrowse link
G Elk1 ELK1, member of ETS oncogene family multiple interactions
increases phosphorylation		 ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of ELK1 mRNA]; pyrazolanthrone inhibits the reaction [Curcumin results in increased phosphorylation of ELK1 protein]; U 0126 inhibits the reaction [Curcumin results in increased phosphorylation of ELK1 protein] CTD PMID:18316600 PMID:23452621 NCBI chr  X:20,799,634...20,816,847
Ensembl chr  X:20,799,634...20,816,847 		JBrowse link
G Emb embigin multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of EMB mRNA] CTD PMID:18200517 NCBI chr13:117,357,109...117,410,951
Ensembl chr13:117,345,072...117,410,951 		JBrowse link
G Eno1 enolase 1, alpha non-neuron decreases expression ISO Curcumin results in decreased expression of ENO1 mRNA CTD PMID:16880289 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336 		JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 increases expression ISO Curcumin results in increased expression of ENTPD5 mRNA CTD PMID:18299980 NCBI chr12:84,420,649...84,455,803
Ensembl chr12:84,420,631...84,455,803 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions
decreases activity
decreases expression
affects localization		 ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin affects the localization of EP300 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of EP300 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of EP300 protein]; Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [EP300 protein binds to KLK3 enhancer]]
Curcumin results in decreased activity of EP300 protein
Curcumin inhibits the reaction [AGT protein modified form promotes the reaction [TP53 protein binds to EP300 protein]]; Curcumin inhibits the reaction [Streptozocin results in increased expression of EP300 mRNA]; Curcumin inhibits the reaction [TP53 protein binds to EP300 protein]
Curcumin results in decreased expression of EP300 mRNA; Curcumin results in decreased expression of EP300 protein		 CTD PMID:17927689 PMID:22228707 PMID:22258452 PMID:26612707 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO Curcumin analog inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:20554536 NCBI chr17:87,061,292...87,140,838
Ensembl chr17:87,061,128...87,140,838 		JBrowse link
G Epcam epithelial cell adhesion molecule decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of EPCAM mRNA; Curcumin results in decreased expression of EPCAM protein
WWTR1 protein inhibits the reaction [Curcumin results in decreased expression of EPCAM mRNA]; WWTR1 protein inhibits the reaction [Curcumin results in decreased expression of EPCAM protein]		 CTD PMID:33539684 NCBI chr17:87,943,407...87,958,555
Ensembl chr17:87,943,407...87,958,557 		JBrowse link
G Epo erythropoietin decreases expression ISO Curcumin results in decreased expression of EPO mRNA CTD PMID:16880289 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504 		JBrowse link
G Epx eosinophil peroxidase multiple interactions EXP [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of EPX protein]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of EPX protein] CTD PMID:34998855 NCBI chr11:87,754,824...87,766,362
Ensembl chr11:87,754,826...87,766,362 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions
increases response to substance
increases degradation
decreases expression		 ISO [ERBB2 protein results in increased susceptibility to Curcumin analog] which results in decreased phosphorylation of AK1 protein; [ERBB2 protein results in increased susceptibility to Curcumin analog] which results in decreased phosphorylation of MAPK1 protein; [ERBB2 protein results in increased susceptibility to Curcumin analog] which results in decreased phosphorylation of MAPK3 protein; Curcumin analog inhibits the reaction [ERBB2 protein results in decreased susceptibility to Doxorubicin]; Curcumin analog inhibits the reaction [ERBB2 protein results in decreased susceptibility to Etoposide]; Curcumin analog inhibits the reaction [ERBB2 protein results in decreased susceptibility to Paclitaxel]; Curcumin analog promotes the reaction [Cycloheximide results in increased degradation of ERBB2 protein]; Curcumin promotes the reaction [Fluorouracil results in decreased phosphorylation of and results in decreased expression of and results in decreased activity of ERBB2 protein]; Curcumin promotes the reaction [Folfox protocol results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB2 protein]; Curcumin results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB2 protein
ERBB2 protein results in increased susceptibility to Curcumin; ERBB2 protein results in increased susceptibility to Curcumin analog
Curcumin analog results in increased degradation of ERBB2 protein
Curcumin analog results in decreased expression of ERBB2 mRNA; Curcumin analog results in decreased expression of ERBB2 protein; Curcumin results in decreased expression of ERBB2 mRNA; Curcumin results in decreased expression of ERBB2 protein		 CTD PMID:17041101 PMID:17918158 PMID:18719366 PMID:25866362 PMID:26409325 More... NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 multiple interactions
decreases expression		 ISO Curcumin promotes the reaction [Folfox protocol results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein]; Curcumin results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein; Fluorouracil promotes the reaction [Curcumin results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of ERBB3 protein]
Curcumin analog results in decreased expression of ERBB3 mRNA; Curcumin results in decreased expression of ERBB3 mRNA		 CTD PMID:15713895 PMID:17918158 PMID:26409325 NCBI chr10:128,403,392...128,425,504
Ensembl chr10:128,403,392...128,425,521 		JBrowse link
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 multiple interactions
decreases expression		 ISO [Curcumin results in decreased expression of ERCC1 protein] which results in increased susceptibility to Cisplatin; Curcumin inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of ERCC1 protein]
Curcumin inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA]
Curcumin results in decreased expression of ERCC1 mRNA; Curcumin results in decreased expression of ERCC1 protein		 CTD PMID:17596214 PMID:21493726 PMID:22228707 NCBI chr 7:19,079,016...19,090,449
Ensembl chr 7:19,078,703...19,090,449 		JBrowse link
G Ercc4 excision repair cross-complementing rodent repair deficiency, complementation group 4 decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of ERCC4 mRNA; Curcumin results in decreased expression of ERCC4 protein
Curcumin inhibits the reaction [Streptozocin results in increased expression of ERCC4 mRNA]
Curcumin inhibits the reaction [Glucose results in increased expression of ERCC4 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of ERCC4 protein]		 CTD PMID:22228707 NCBI chr16:12,927,600...12,969,873
Ensembl chr16:12,927,548...12,968,481 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signalling 1 decreases expression
increases expression		 ISO Curcumin results in decreased expression of ERN1 mRNA
Curcumin results in increased expression of ERN1 mRNA		 CTD PMID:17999991 PMID:29723631 NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [bisphenol A results in increased expression of ESR1 protein]; Curcumin inhibits the reaction [Estradiol results in increased degradation of ESR1 protein]; Curcumin inhibits the reaction [Estradiol results in increased phosphorylation of ESR1 protein]; Curcumin inhibits the reaction [fulvestrant results in increased degradation of ESR1 protein]
Curcumin results in decreased expression of ESR1 protein		 CTD PMID:15899841 PMID:18347134 PMID:23222814 PMID:24211270 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Ets2 E26 avian leukemia oncogene 2, 3' domain decreases expression ISO Curcumin results in decreased expression of ETS2 protein CTD PMID:17332326 NCBI chr16:95,503,274...95,522,093
Ensembl chr16:95,502,942...95,522,095 		JBrowse link
G F2 coagulation factor II multiple interactions ISO Curcumin inhibits the reaction [F2 protein results in increased expression of ITGA2B protein]; Curcumin inhibits the reaction [F2 protein results in increased expression of ITGB3 protein]; Curcumin inhibits the reaction [F2 protein results in increased expression of SELE protein]; Curcumin inhibits the reaction [F2 protein results in increased expression of SELP protein] CTD PMID:18565277 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759 		JBrowse link
G F2r coagulation factor II thrombin receptor multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of F2R mRNA] CTD PMID:23452621 NCBI chr13:95,738,288...95,754,974
Ensembl chr13:95,738,311...95,754,995 		JBrowse link
G F3 coagulation factor III multiple interactions ISO Curcumin inhibits the reaction [Heme results in increased expression of F3 mRNA] CTD PMID:18983524 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697 		JBrowse link
G Fadd Fas associated via death domain multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of FADD mRNA] CTD PMID:23452621 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200 		JBrowse link
G Fads1 fatty acid desaturase 1 affects expression
decreases expression		 EXP
ISO		 Curcumin affects the expression of FADS1 mRNA
Curcumin results in decreased expression of FADS1 mRNA		 CTD PMID:27208389 NCBI chr19:10,160,245...10,174,238
Ensembl chr19:10,160,252...10,174,241 		JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression
affects expression		 ISO
EXP		 Curcumin results in decreased expression of FADS2 mRNA
Curcumin affects the expression of FADS2 mRNA		 CTD PMID:27208389 NCBI chr19:10,040,129...10,078,867
Ensembl chr19:10,040,129...10,079,110 		JBrowse link
G Fam120b family with sequence similarity 120, member B decreases expression ISO Curcumin results in decreased expression of FAM120B mRNA CTD PMID:17999991 NCBI chr17:15,616,464...15,653,843
Ensembl chr17:15,616,464...15,653,845 		JBrowse link
G Fancd2 Fanconi anemia, complementation group D2 multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Mitomycin results in increased expression of and affects the ubiquitination of FANCD2 protein]
Curcumin results in decreased expression of FANCD2 mRNA		 CTD PMID:24124520 NCBI chr 6:113,508,622...113,573,981
Ensembl chr 6:113,508,643...113,573,978 		JBrowse link
G Fanci Fanconi anemia, complementation group I multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Mitomycin results in increased expression of and affects the ubiquitination of FANCI protein]
Curcumin results in decreased expression of FANCI mRNA		 CTD PMID:24124520 NCBI chr 7:79,042,056...79,100,013
Ensembl chr 7:79,041,677...79,100,012 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO [arsenic trioxide co-treated with Curcumin] results in increased expression of FAS protein CTD PMID:27430728 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fasl Fas ligand multiple interactions
decreases expression		 ISO [arsenic trioxide co-treated with Curcumin] results in increased expression of FASLG protein; Curcumin inhibits the reaction [[vorinostat co-treated with Bortezomib] results in increased expression of FASLG protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of FASLG mRNA]
Curcumin results in decreased expression of FASLG mRNA		 CTD PMID:10925121 PMID:16101141 PMID:17351739 PMID:23452621 PMID:27430728 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Fasn fatty acid synthase affects expression
decreases expression		 EXP
ISO		 Curcumin affects the expression of FASN mRNA; Curcumin affects the expression of FASN protein
Curcumin results in decreased expression of FASN mRNA		 CTD PMID:27208389 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373 		JBrowse link
G Fbln2 fibulin 2 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FBLN2 mRNA] CTD PMID:18200517 NCBI chr 6:91,189,442...91,249,522
Ensembl chr 6:91,189,437...91,249,522 		JBrowse link
G Fcgr4 Fc receptor, IgG, low affinity IV multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FCGR3A mRNA] CTD PMID:18200517 NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression ISO Curcumin results in decreased expression of FDFT1 mRNA CTD PMID:27208389 NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027 		JBrowse link
G Fdps farnesyl diphosphate synthetase increases expression
decreases expression
affects expression		 ISO
EXP		 Curcumin results in increased expression of FDPS mRNA
Curcumin results in decreased expression of FDPS mRNA
Curcumin affects the expression of FDPS mRNA		 CTD PMID:16713233 PMID:27208389 NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266 		JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression
increases expression		 ISO Curcumin results in decreased expression of FGF2 protein
Curcumin results in increased expression of FGF2 protein		 CTD PMID:23555722 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257 		JBrowse link
G Fgf5 fibroblast growth factor 5 decreases expression EXP Curcumin results in decreased expression of FGF5 mRNA CTD PMID:27237783 NCBI chr 5:98,402,108...98,424,892
Ensembl chr 5:98,402,043...98,424,889 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 decreases expression ISO Curcumin results in decreased expression of FGFR2 mRNA CTD PMID:15713895 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079 		JBrowse link
G Filip1l filamin A interacting protein 1-like increases expression ISO Curcumin results in increased expression of FILIP1L mRNA CTD PMID:21594647 NCBI chr16:57,173,376...57,393,167
Ensembl chr16:57,173,456...57,393,489 		JBrowse link
G Fis1 fission, mitochondrial 1 multiple interactions ISO Curcumin inhibits the reaction [Cisplatin results in increased expression of FIS1 protein] CTD PMID:28698153 NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088 		JBrowse link
G Flt1 FMS-like tyrosine kinase 1 decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of FLT1 protein
Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of FLT1 protein]		 CTD PMID:18593936 PMID:23845850 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821 		JBrowse link
G Fn1 fibronectin 1 multiple interactions
decreases expression		 ISO
EXP		 Curcumin inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of FN1 protein]
Curcumin inhibits the reaction [sphingosine 1-phosphate results in increased expression of FN1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]
Curcumin results in decreased expression of FN1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FN1 mRNA]		 CTD PMID:12388107 PMID:18200517 PMID:18555241 PMID:21998146 PMID:22228707 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359 		JBrowse link
G Fntb farnesyltransferase, CAAX box, beta increases expression ISO Curcumin results in increased expression of FNTB mRNA CTD PMID:17999991 NCBI chr12:76,884,014...76,968,188
Ensembl chr12:76,812,363...76,968,186 		JBrowse link
G Fos FBJ osteosarcoma oncogene decreases expression
multiple interactions
increases expression		 ISO
EXP		 Curcumin results in decreased expression of FOS mRNA
Curcumin inhibits the reaction [Tobacco Smoke Pollution results in increased phosphorylation of FOS protein]
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of FOS mRNA]
Curcumin results in increased expression of FOS mRNA
[Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of FOS protein]		 CTD PMID:15713895 PMID:17827730 PMID:17999991 PMID:23452621 PMID:26191140 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Fosl1 fos-like antigen 1 multiple interactions
increases ubiquitination		 ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein]
Curcumin results in increased ubiquitination of FOSL1 protein		 CTD PMID:17148446 NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974 		JBrowse link
G Fosl2 fos-like antigen 2 decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of FOSL2 mRNA
Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL2 protein]		 CTD PMID:17148446 PMID:17999991 NCBI chr 5:32,292,599...32,315,184
Ensembl chr 5:32,293,145...32,315,186 		JBrowse link
G Foxa1 forkhead box A1 multiple interactions ISO Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [FOXA1 protein binds to KLK3 enhancer]]; Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [FOXA1 protein binds to TMPRSS2 enhancer]] CTD PMID:22258452 NCBI chr12:57,585,750...57,594,815
Ensembl chr12:57,587,414...57,593,702 		JBrowse link
G Foxa2 forkhead box A2 decreases expression EXP Curcumin results in decreased expression of FOXA2 mRNA CTD PMID:27237783 NCBI chr 2:147,884,797...147,888,889
Ensembl chr 2:147,884,797...147,888,889 		JBrowse link
G Foxf2 forkhead box F2 decreases expression ISO Curcumin results in decreased expression of FOXF2 mRNA CTD PMID:15713895 NCBI chr13:31,809,686...31,815,390
Ensembl chr13:31,809,799...31,815,386 		JBrowse link
G Foxo1 forkhead box O1 increases expression
decreases phosphorylation		 EXP
ISO		 Curcumin results in increased expression of FOXO1 mRNA
Curcumin results in decreased phosphorylation of FOXO1 protein		 CTD PMID:18403477 PMID:18790744 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642 		JBrowse link
G Fpr3 formyl peptide receptor 3 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FPR3 mRNA] CTD PMID:18200517 NCBI chr17:18,190,720...18,191,939
Ensembl chr17:18,108,114...18,191,939 		JBrowse link
G Fshb follicle stimulating hormone beta multiple interactions ISO Curcumin inhibits the reaction [sodium arsenite results in decreased expression of FSHB protein] CTD PMID:31199764 NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001 		JBrowse link
G Fstl1 follistatin-like 1 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of FSTL1 mRNA] CTD PMID:18200517 NCBI chr16:37,597,417...37,656,878
Ensembl chr16:37,597,235...37,656,876 		JBrowse link
G Ftl1 ferritin light polypeptide 1 decreases expression EXP Curcumin results in decreased expression of FTL1 mRNA CTD PMID:24634837 NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308 		JBrowse link
G Fus fused in sarcoma increases expression
decreases expression		 ISO Curcumin results in increased expression of FUS mRNA
Curcumin results in decreased expression of FUS mRNA		 CTD PMID:17198877 PMID:17999991 NCBI chr 7:127,565,276...127,581,204
Ensembl chr 7:127,566,629...127,584,873 		JBrowse link
G Fzd1 frizzled class receptor 1 decreases expression ISO Curcumin results in decreased expression of FZD1 mRNA CTD PMID:15713895 NCBI chr 5:4,803,839...4,808,216
Ensembl chr 5:4,803,839...4,808,035 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 affects expression EXP Curcumin affects the expression of G6PC1 mRNA CTD PMID:27208389 NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729 		JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked increases expression
multiple interactions		 ISO Curcumin results in increased expression of G6PD mRNA; Curcumin results in increased expression of G6PDX mRNA
Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of G6PD protein]		 CTD PMID:18299980 PMID:36924976 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800 		JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 decreases expression ISO Curcumin results in decreased expression of GABRA1 mRNA CTD PMID:18299980 NCBI chr11:42,021,766...42,073,893
Ensembl chr11:42,021,766...42,073,757 		JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions ISO Curcumin inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA] CTD PMID:23267840 NCBI chr 2:70,392,109...70,432,358
Ensembl chr 2:70,383,416...70,432,358 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha increases expression ISO Curcumin results in increased expression of GADD45A mRNA CTD PMID:16101141 PMID:18299980 PMID:18719366 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441 		JBrowse link
G Gas6 growth arrest specific 6 increases expression ISO Curcumin results in increased expression of GAS6 mRNA CTD PMID:21594647 NCBI chr 8:13,515,374...13,544,535
Ensembl chr 8:13,515,374...13,544,490 		JBrowse link
G Gata2 GATA binding protein 2 multiple interactions ISO Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [GATA2 protein binds to KLK3 enhancer]]; Curcumin inhibits the reaction [Dihydrotestosterone promotes the reaction [GATA2 protein binds to TMPRSS2 enhancer]]; Curcumin inhibits the reaction [GATA2 protein results in increased expression of KLK3 mRNA] CTD PMID:22258452 NCBI chr 6:88,170,873...88,184,014
Ensembl chr 6:88,170,873...88,184,014 		JBrowse link
G Gata4 GATA binding protein 4 decreases expression EXP Curcumin results in decreased expression of GATA4 mRNA; Curcumin results in decreased expression of GATA4 protein CTD PMID:27237783 NCBI chr14:63,436,363...63,509,161
Ensembl chr14:63,436,371...63,509,141 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases activity
multiple interactions
increases expression		 ISO
EXP		 Curcumin results in increased activity of GCLC protein
Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of GCLC mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of GCLC mRNA]; Curcumin promotes the reaction [sodium arsenite results in increased expression of GCLC protein]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of GCLC mRNA]
Curcumin analog results in increased expression of GCLC mRNA; Curcumin results in increased expression of GCLC mRNA
Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of GCLC mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of GCLC mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of GCLC mRNA]
Curcumin results in increased expression of GCLC mRNA; Curcumin results in increased expression of GCLC protein
Curcumin inhibits the reaction [Ketamine results in decreased expression of GCLC mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of GCLC protein]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC protein]; Curcumin results in increased activity of [GCLC protein binds to GCLM protein]		 CTD PMID:10514034 PMID:17602960 PMID:18299980 PMID:18332871 PMID:19168576 More... NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767 		JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit multiple interactions
increases expression		 ISO
EXP		 Curcumin results in increased activity of [GCLC protein binds to GCLM protein]
Curcumin promotes the reaction [sodium arsenite results in increased expression of GCLM mRNA]
Curcumin analog results in increased expression of GCLM mRNA; Curcumin results in increased expression of GCLM mRNA; Curcumin results in increased expression of GCLM protein
NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of GCLM mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of GCLM mRNA]		 CTD PMID:17198877 PMID:17535857 PMID:17602960 PMID:17999991 PMID:18332871 More... NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381 		JBrowse link
G Gda guanine deaminase multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GDA mRNA] CTD PMID:18200517 NCBI chr19:21,368,671...21,450,025
Ensembl chr19:21,368,671...21,450,809 		JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
multiple interactions		 EXP
ISO		 Curcumin results in decreased expression of GFAP mRNA
Curcumin inhibits the reaction [bisphenol A results in increased expression of GFAP mRNA]		 CTD PMID:19555370 PMID:25963729 NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases expression
multiple interactions		 ISO Curcumin results in increased expression of GGT1 mRNA
Curcumin inhibits the reaction [Thioacetamide results in increased expression of GGT1 protein]		 CTD PMID:18299980 PMID:24704557 NCBI chr10:75,396,910...75,422,027
Ensembl chr10:75,397,438...75,422,034 		JBrowse link
G Ggta1 glycoprotein galactosyltransferase alpha 1, 3 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GGTA1 mRNA] CTD PMID:18200517 NCBI chr 2:35,290,191...35,354,393
Ensembl chr 2:35,290,191...35,353,243 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of GJA1 mRNA] CTD PMID:23452621 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609 		JBrowse link
G Gli1 GLI-Kruppel family member GLI1 decreases expression
multiple interactions		 EXP
ISO		 Curcumin results in decreased expression of GLI1 mRNA; Curcumin results in decreased expression of GLI1 protein
[Arsenic Trioxide co-treated with Curcumin] inhibits the reaction [Cisplatin results in increased expression of GLI1 protein]; Curcumin inhibits the reaction [Cisplatin results in increased expression of GLI1 protein]		 CTD PMID:20395211 PMID:31612257 NCBI chr10:127,165,751...127,177,448
Ensembl chr10:127,165,751...127,177,843 		JBrowse link
G Gli2 GLI-Kruppel family member GLI2 multiple interactions ISO Curcumin inhibits the reaction [Cisplatin results in increased expression of GLI2 protein]; Curcumin promotes the reaction [Arsenic Trioxide inhibits the reaction [Cisplatin results in increased expression of GLI2 protein]] CTD PMID:31612257 NCBI chr 1:118,761,791...118,987,578
Ensembl chr 1:118,761,862...118,981,349 		JBrowse link
G Glo1 glyoxalase 1 decreases activity ISO Curcumin results in decreased activity of GLO1 protein CTD PMID:18946510 NCBI chr17:30,811,835...30,831,633
Ensembl chr17:30,803,910...30,845,845 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble multiple interactions ISO Curcumin inhibits the reaction [aristolochic acid I results in increased activity of GOT1 protein]; Curcumin inhibits the reaction [ferric sulfate results in increased activity of GOT1 protein]; Curcumin inhibits the reaction [Iron results in increased activity of GOT1 protein] CTD PMID:16956363 PMID:36037877 NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044 		JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GOT1L1 mRNA] CTD PMID:18200517 NCBI chr 8:27,687,487...27,713,872
Ensembl chr 8:27,687,487...27,713,856 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression
affects expression
multiple interactions		 EXP
ISO		 Curcumin results in decreased expression of GPAM mRNA
Curcumin affects the expression of GPAM mRNA
Curcumin inhibits the reaction [Dietary Fats results in increased expression of GPAM mRNA]		 CTD PMID:19297423 PMID:27208389 NCBI chr19:55,056,067...55,115,666
Ensembl chr19:55,055,700...55,115,670 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 decreases expression ISO Curcumin results in decreased expression of GPER1 mRNA CTD PMID:17198877 NCBI chr 5:139,408,905...139,413,555
Ensembl chr 5:139,408,906...139,413,555 		JBrowse link
G Gphn gephyrin affects expression ISO Curcumin affects the expression of GPHN mRNA CTD PMID:18539377 NCBI chr12:78,264,099...78,731,546
Ensembl chr12:78,273,153...78,731,546 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions ISO
EXP		 [Curcumin analog co-treated with Hydrogels] inhibits the reaction [Aflatoxin B1 results in increased activity of GPT protein]; Curcumin inhibits the reaction [Acetaminophen affects the activity of GPT protein]; Curcumin inhibits the reaction [aristolochic acid I results in increased activity of GPT protein]; Curcumin inhibits the reaction [Cadmium Chloride results in increased activity of GPT protein]; Curcumin inhibits the reaction [Fenitrothion results in increased expression of GPT protein]; Curcumin inhibits the reaction [ferric sulfate results in increased activity of GPT protein]; Curcumin inhibits the reaction [Iron results in increased activity of GPT protein]; Curcumin inhibits the reaction [Thioacetamide results in increased activity of GPT protein]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of GPT protein]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in increased activity of GPT protein]]
Curcumin inhibits the reaction [Aflatoxin B1 results in increased activity of GPT protein]; Curcumin inhibits the reaction [bisphenol A results in increased activity of GPT protein]; Curcumin inhibits the reaction [Chloranil results in increased activity of GPT protein]; Curcumin metabolite inhibits the reaction [Acetaminophen results in increased expression of GPT protein]		 CTD PMID:16956363 PMID:20804811 PMID:24704557 PMID:25123790 PMID:27288928 More... NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression
multiple interactions		 ISO
EXP		 Curcumin results in decreased expression of GPX1 mRNA
Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of GPX1 protein]
Curcumin inhibits the reaction [sodium arsenite results in decreased expression of GPX1 mRNA]
[Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in increased expression of GPX1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; Curcumin inhibits the reaction [Thyroxine results in decreased expression of GPX1 mRNA]		 CTD PMID:18299980 PMID:19914224 PMID:23267840 PMID:30934151 PMID:36924976 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Grb10 growth factor receptor bound protein 10 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GRB10 mRNA] CTD PMID:18200517 NCBI chr11:11,880,499...11,987,428
Ensembl chr11:11,880,508...11,988,683 		JBrowse link
G Grb2 growth factor receptor bound protein 2 decreases expression ISO Curcumin analog results in decreased expression of GRB2 mRNA CTD PMID:26409325 NCBI chr11:115,534,871...115,599,423
Ensembl chr11:115,534,871...115,599,423 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GREM1 mRNA] CTD PMID:18200517 NCBI chr 2:113,579,020...113,588,993
Ensembl chr 2:113,576,509...113,588,991 		JBrowse link
G Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4) multiple interactions ISO Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein] CTD PMID:23267840 NCBI chr 9:4,417,893...4,796,250
Ensembl chr 9:4,417,896...4,796,234 		JBrowse link
G Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) multiple interactions ISO Curcumin inhibits the reaction [sodium arsenite results in decreased expression of GRIN1 mRNA]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of GRIN1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein] CTD PMID:23267840 PMID:29723552 NCBI chr 2:25,181,189...25,209,199
Ensembl chr 2:25,181,193...25,209,199 		JBrowse link
G Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) multiple interactions ISO Curcumin inhibits the reaction [aluminum acetate results in decreased expression of GRIN2A protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of GRIN2A mRNA]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of GRIN2A protein] CTD PMID:25496357 PMID:29723552 NCBI chr16:9,385,765...9,813,744
Ensembl chr16:9,385,762...9,813,424 		JBrowse link
G Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) multiple interactions ISO Curcumin inhibits the reaction [aluminum acetate results in decreased expression of GRIN2B protein] CTD PMID:25496357 NCBI chr 6:135,690,219...136,150,658
Ensembl chr 6:135,690,231...136,150,509 		JBrowse link
G Grm2 glutamate receptor, metabotropic 2 decreases expression EXP Curcumin results in decreased expression of GRM2 protein CTD PMID:25406541 NCBI chr 9:106,521,733...106,533,308
Ensembl chr 9:106,520,294...106,533,281 		JBrowse link
G Gsdmd gasdermin D multiple interactions EXP [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of GSDMD protein]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of GSDMD mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of GSDMD protein] CTD PMID:34998855 PMID:35063475 NCBI chr15:75,733,990...75,739,257
Ensembl chr15:75,734,176...75,739,257 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation
decreases expression
multiple interactions
increases phosphorylation
increases expression		 ISO
EXP		 Curcumin results in decreased phosphorylation of GSK3B protein
Curcumin results in decreased expression of GSK3B mRNA
Curcumin inhibits the reaction [IL1B protein results in decreased expression of GSK3B mRNA]; Curcumin inhibits the reaction [IL1B protein results in increased expression of GSK3B protein]; Curcumin results in increased expression of and results in increased phosphorylation of GSK3B protein
Curcumin results in increased phosphorylation of GSK3B protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of GSK3B protein]]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased phosphorylation of GSK3B protein]; Curcumin inhibits the reaction [bisphenol A results in decreased phosphorylation of GSK3B protein]; Curcumin inhibits the reaction [bisphenol A results in increased expression of GSK3B mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased phosphorylation of and affects the localization of GSK3B protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of GSK3B protein]; Curcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]
Curcumin results in increased expression of GSK3B protein		 CTD PMID:18006147 PMID:18790744 PMID:19573523 PMID:25541178 PMID:25963729 More... NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Gsn gelsolin multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GSN mRNA] CTD PMID:18200517 NCBI chr 2:35,146,371...35,197,914
Ensembl chr 2:35,146,392...35,197,904 		JBrowse link
G Gsr glutathione reductase increases expression
multiple interactions		 EXP
ISO		 Curcumin results in increased expression of GSR mRNA
Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of GSR protein]
[Curcumin co-treated with resveratrol] inhibits the reaction [Benzo(a)pyrene results in decreased activity of GSR protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of GSR]
[Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in decreased expression of GSR mRNA]; Curcumin analog inhibits the reaction [Monocrotaline results in increased activity of GSR protein]; Curcumin analog inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]; Curcumin inhibits the reaction [Fenitrothion results in decreased activity of GSR protein]; Curcumin inhibits the reaction [Hexachlorocyclohexane results in decreased activity of GSR protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]; Curcumin inhibits the reaction [Thyroxine results in decreased expression of GSR mRNA]		 CTD PMID:19168576 PMID:19914224 PMID:20593964 PMID:21976817 PMID:24347089 More... NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191 		JBrowse link
G Gss glutathione synthetase increases expression
multiple interactions		 EXP Curcumin results in increased expression of GSS mRNA
Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of GSS mRNA]		 CTD PMID:19183254 PMID:35063475 NCBI chr 2:155,405,101...155,434,730
Ensembl chr 2:155,405,101...155,434,730 		JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) increases expression ISO Curcumin results in increased expression of GSTA5 mRNA CTD PMID:18299980 NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP Curcumin results in increased expression of GSTA2 mRNA CTD PMID:18200517 NCBI chr 9:78,197,210...78,212,807
Ensembl chr 9:78,197,205...78,212,807 		JBrowse link
G Gstk1 glutathione S-transferase kappa 1 multiple interactions ISO Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of GSTK1 mRNA] CTD PMID:31521693 NCBI chr 6:42,222,869...42,227,375
Ensembl chr 6:42,222,869...42,227,381 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 increases expression
multiple interactions		 EXP Curcumin results in increased expression of GSTO1 mRNA
Curcumin promotes the reaction [sodium arsenite results in increased expression of GSTO1 mRNA]		 CTD PMID:34272803 NCBI chr19:47,843,412...47,853,229
Ensembl chr19:47,843,409...47,853,229 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 multiple interactions
affects expression
increases expression
decreases expression		 ISO [sulfinosine co-treated with Curcumin] results in decreased expression of GSTP1 mRNA; Curcumin binds to and results in decreased activity of GSTP1 protein; Curcumin inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]; Curcumin inhibits the reaction [TNF protein results in increased expression of GSTP1 mRNA]; Curcumin promotes the reaction [NFE2L2 protein binds to GSTP1 promoter]; Curcumin promotes the reaction [NFE2L2 protein results in increased expression of GSTP1 mRNA]
Curcumin affects the expression of GSTP1 protein
Curcumin results in increased expression of GSTP1 mRNA
Curcumin results in increased expression of GSTP1 mRNA; Curcumin results in increased expression of GSTP1 protein
Curcumin results in decreased expression of GSTP1 mRNA; Curcumin results in decreased expression of GSTP1 protein		 CTD PMID:9463521 PMID:14555224 PMID:14742295 PMID:15999103 PMID:16101141 More... NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985 		JBrowse link
G Gusb glucuronidase, beta multiple interactions ISO Curcumin inhibits the reaction [Isoproterenol results in increased activity of GUSB protein] CTD PMID:8534267 NCBI chr 5:130,011,278...130,031,890
Ensembl chr 5:130,017,852...130,031,890 		JBrowse link
G H19 H19, imprinted maternally expressed transcript decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of H19 mRNA
curcumin inhibits the reaction [platelet- derived growth factor increases expression of H19 RNA in aortic vascular smooth muscle cells]
curcumin inhibits the reaction [carotid balloon injury increases expression of H19 RNA in carotid artery segment]		 CTD
RGD		 PMID:18348204 PMID:34487706 PMID:34487706 RGD:156430326, RGD:156430326 NCBI chr 7:142,129,267...142,131,883
Ensembl chr 7:142,129,262...142,131,917 		JBrowse link
G H1f10 H1.10 linker histone decreases expression ISO Curcumin results in decreased expression of H1-10 mRNA CTD PMID:17198877 NCBI chr 6:87,957,403...87,958,464
Ensembl chr 6:87,957,403...87,958,619 		JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases phosphorylation		 ISO [Curcumin co-treated with Metribolone] results in increased phosphorylation of H2AX protein; [Isoflavones co-treated with Curcumin] results in increased phosphorylation of H2AX protein
Curcumin results in increased phosphorylation of H2AX protein		 CTD PMID:19401701 PMID:21134073 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374 		JBrowse link
G H2bc14 H2B clustered histone 14 increases expression ISO Curcumin results in increased expression of H2BC5 mRNA CTD PMID:17999991 NCBI chr13:21,906,214...21,906,696
Ensembl chr13:21,906,214...21,906,737 		JBrowse link
G H2bc26 H2B clustered histone 26 increases expression ISO Curcumin results in increased expression of H2BC26 mRNA CTD PMID:15713895 NCBI chr11:58,842,961...58,845,278
Ensembl chr11:58,844,874...58,845,254 		JBrowse link
G H3f4 H3.4 histone, cluster member increases phosphorylation
increases acetylation		 ISO Curcumin results in increased phosphorylation of H3F4 protein
Curcumin results in increased acetylation of H3F4 protein		 CTD PMID:18204486 NCBI chr11:58,852,537...58,853,099
Ensembl chr11:58,852,599...58,853,364 		JBrowse link
G H4c11 H4 clustered histone 11 increases expression ISO Curcumin results in increased expression of H4C11 mRNA CTD PMID:15713895 NCBI chr13:21,919,204...21,919,626
Ensembl chr13:21,919,234...21,920,007 		JBrowse link
G H4c4 H4 clustered histone 4 increases expression ISO Curcumin results in increased expression of H4C15 mRNA CTD PMID:17198877 NCBI chr13:23,765,551...23,765,952
Ensembl chr13:23,765,581...23,766,718 		JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression EXP Curcumin results in decreased expression of HAMP mRNA CTD PMID:24634837 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457 		JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 multiple interactions
decreases expression		 EXP Curcumin inhibits the reaction [Alcohols results in increased expression of HAND1 mRNA]
Curcumin results in decreased expression of HAND1 mRNA		 CTD PMID:24857828 NCBI chr11:57,719,539...57,722,973
Ensembl chr11:57,719,531...57,723,644 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 multiple interactions
decreases expression		 EXP Curcumin inhibits the reaction [Alcohols results in increased expression of HAND2 mRNA]
Curcumin results in decreased expression of HAND2 mRNA		 CTD PMID:24857828 NCBI chr 8:57,774,018...57,777,552
Ensembl chr 8:57,774,018...57,777,668 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions ISO Curcumin analog inhibits the reaction [Copper Sulfate results in increased expression of HAVCR1 protein]; Curcumin inhibits the reaction [Cadmium Chloride results in increased export of HAVCR1 protein]; Curcumin inhibits the reaction [Copper Sulfate results in increased expression of HAVCR1 protein]; Curcumin inhibits the reaction [maleic acid results in increased expression of HAVCR1 protein] CTD PMID:25119790 PMID:29421648 PMID:30431687 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405 		JBrowse link
G Hbs1l Hbs1-like (S. cerevisiae) decreases expression ISO Curcumin results in decreased expression of HBS1L mRNA CTD PMID:18421014 NCBI chr10:21,171,876...21,244,788
Ensembl chr10:21,171,878...21,244,797 		JBrowse link
G Hck hemopoietic cell kinase decreases activity
multiple interactions		 ISO Curcumin analog results in decreased activity of HCK protein
[Curcumin binds to 3,4,5-trimethoxybenzaldehyde] which results in decreased activity of HCK protein; [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] inhibits the reaction [HCK protein binds to Adenosine Triphosphate]; [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] which binds to and results in decreased phosphorylation of and results in decreased activity of HCK protein		 CTD PMID:33617879 NCBI chr 2:152,950,388...152,993,361
Ensembl chr 2:152,950,388...152,993,361 		JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions
decreases expression
affects localization		 ISO
EXP		 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin affects the localization of HDAC1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of HDAC1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of HDAC1 protein]
Curcumin analog results in decreased expression of HDAC1 protein
Curcumin analog results in decreased expression of HDAC1 mRNA; Curcumin results in decreased expression of HDAC1 mRNA; Curcumin results in decreased expression of HDAC1 protein		 CTD PMID:17927689 PMID:18161303 PMID:23593078 PMID:26409325 PMID:29228771 NCBI chr 4:129,409,897...129,436,516
Ensembl chr 4:129,409,897...129,436,506 		JBrowse link
G Hdac11 histone deacetylase 11 decreases expression ISO Curcumin analog results in decreased expression of HDAC11 mRNA CTD PMID:26409325 NCBI chr 6:91,133,652...91,151,674
Ensembl chr 6:91,133,647...91,151,674 		JBrowse link
G Hdac2 histone deacetylase 2 multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased activity of HDAC2 protein]; Curcumin inhibits the reaction [Smoke results in decreased activity of HDAC2 protein]; Curcumin inhibits the reaction [Smoke results in increased degradation of and results in decreased expression of HDAC2 protein]
Curcumin analog results in decreased expression of HDAC2 mRNA		 CTD PMID:18421014 PMID:26409325 NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885 		JBrowse link
G Hdac3 histone deacetylase 3 decreases expression ISO Curcumin results in decreased expression of HDAC3 protein CTD PMID:17927689 NCBI chr18:38,070,024...38,088,073
Ensembl chr18:38,068,897...38,088,069 		JBrowse link
G Hdac4 histone deacetylase 4 decreases expression ISO
EXP		 Curcumin analog results in decreased expression of HDAC4 mRNA
Curcumin analog results in decreased expression of HDAC4 protein		 CTD PMID:26409325 PMID:26991801 PMID:29228771 NCBI chr 1:91,856,501...92,123,424
Ensembl chr 1:91,856,501...92,123,421 		JBrowse link
G Hdac6 histone deacetylase 6 decreases expression ISO Curcumin analog results in decreased expression of HDAC6 mRNA CTD PMID:26409325 NCBI chr  X:7,796,355...7,814,284
Ensembl chr  X:7,796,359...7,814,128 		JBrowse link
G Hdac7 histone deacetylase 7 decreases expression EXP Curcumin analog results in decreased expression of HDAC7 protein CTD PMID:29228771 NCBI chr15:97,690,542...97,742,383
Ensembl chr15:97,690,545...97,742,383 		JBrowse link
G Hdac8 histone deacetylase 8 decreases expression ISO Curcumin analog results in decreased expression of HDAC8 mRNA CTD PMID:26409325 NCBI chr  X:101,328,244...101,549,005
Ensembl chr  X:101,328,245...101,548,965 		JBrowse link
G Hebp2 heme binding protein 2 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HEBP2 mRNA] CTD PMID:18200517 NCBI chr10:18,415,871...18,421,824
Ensembl chr10:18,415,246...18,421,824 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions EXP [1,2-Dimethylhydrazine co-treated with Curcumin] results in increased expression of HES1 mRNA CTD PMID:22982865 NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614 		JBrowse link
G Hgf hepatocyte growth factor increases expression
decreases expression		 ISO Curcumin results in increased expression of HGF protein
Curcumin results in decreased expression of HGF protein		 CTD PMID:23555722 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions
decreases expression
decreases activity		 ISO
EXP		 [Curcumin analog co-treated with Sirolimus] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; [Curcumin analog co-treated with terpestacin] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; [Curcumin analog co-treated with vorinostat] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Curcumin analog inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; Curcumin analog inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein modified form]; Curcumin analog inhibits the reaction [Ionomycin promotes the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; Curcumin analog inhibits the reaction [Ionomycin results in increased activity of HIF1A protein]; Curcumin analog inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased activity of HIF1A protein]; Curcumin results in decreased expression of and results in decreased activity of HIF1A protein; VHL protein promotes the reaction [Curcumin results in decreased expression of HIF1A protein]
Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of HIF1A mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of HIF1A protein]
Curcumin results in decreased expression of HIF1A mRNA
Curcumin analog results in decreased expression of HIF1A mRNA; Curcumin results in decreased expression of HIF1A mRNA
Curcumin results in decreased activity of HIF1A protein		 CTD PMID:16880289 PMID:18682687 PMID:20554536 PMID:21397623 PMID:23845850 More... NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hk1 hexokinase 1 multiple interactions ISO Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of HK1 protein] CTD PMID:36924976 NCBI chr10:62,104,634...62,215,699
Ensembl chr10:62,104,634...62,215,687 		JBrowse link
G Hk2 hexokinase 2 decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of HK2 protein
4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction [Curcumin results in decreased expression of HK2 protein]; ATF4 inhibits the reaction [Curcumin results in decreased expression of HK2 protein]; Curcumin promotes the reaction [Sirolimus results in decreased expression of HK2 protein]		 CTD PMID:36640941 NCBI chr 6:82,702,004...82,751,437
Ensembl chr 6:82,702,006...82,751,435 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of HMGB1 protein]]; Curcumin inhibits the reaction [Carbon Tetrachloride affects the localization of and affects the secretion of HMGB1 protein]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of HMGB1 mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of HMGB1 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of HMGB1 protein] CTD PMID:22683883 PMID:29480285 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase increases expression
multiple interactions
decreases expression
affects expression		 ISO
EXP		 Curcumin results in increased expression of HMGCR mRNA
Curcumin inhibits the reaction [bisphenol A results in increased expression of HMGCR protein]
Curcumin results in decreased expression of HMGCR mRNA
Curcumin affects the expression of HMGCR mRNA; Curcumin affects the expression of HMGCR protein		 CTD PMID:16713233 PMID:27208389 PMID:37701206 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 decreases expression ISO Curcumin results in decreased expression of HMGCS1 mRNA CTD PMID:27208389 NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
increases expression
decreases response to substance
increases activity		 ISO
EXP		 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; [Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]] which results in increased expression of HMOX1 protein; Acetylcysteine inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of HMOX1 mRNA]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [Furazolidone results in increased expression of HMOX1 protein]; Curcumin promotes the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [quinocetone results in increased activity of HMOX1 protein]; Curcumin promotes the reaction [quinocetone results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [sodium arsenite results in increased expression of HMOX1 protein]; Curcumin results in increased expression of and results in increased activity of HMOX1 protein; Cycloheximide inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Egtazic Acid inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Go 6976 inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Hemin promotes the reaction [Curcumin results in increased expression of HMOX1 mRNA]; MAPK14 protein affects the reaction [Curcumin results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of HMOX1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of HMOX1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in increased expression of HMOX1 protein]]; PRKCA protein affects the reaction [Curcumin results in increased expression of HMOX1 protein]; PRKCD protein affects the reaction [Curcumin results in increased expression of HMOX1 protein]; Ro 31-8220 inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; rottlerin inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; tin protoporphyrin IX inhibits the reaction [Curcumin results in increased activity of HMOX1 protein]
Curcumin results in decreased expression of HMOX1 mRNA
Curcumin analog results in increased expression of HMOX1 mRNA; Curcumin analog results in increased expression of HMOX1 protein; Curcumin results in increased expression of HMOX1 mRNA; Curcumin results in increased expression of HMOX1 protein
[chromium mesoporphyrin inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]]] which results in increased expression of HMOX1 protein; [Curcumin co-treated with Chloranil] results in increased expression of HMOX1 protein; [Curcumin co-treated with piperine] results in increased expression of HMOX1 mRNA; [Curcumin co-treated with piperine] results in increased expression of HMOX1 protein; [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]] which results in increased expression of HMOX1 protein; Acetylcysteine inhibits the reaction [[Curcumin co-treated with piperine] results in increased expression of HMOX1 protein]; AKT1 protein affects the reaction [Curcumin results in increased expression of HMOX1 mRNA]; Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of HMOX1 mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of HMOX1 mRNA]; Curcumin promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 protein]; Curcumin promotes the reaction [sodium arsenite results in increased expression of HMOX1 protein]; Curcumin results in increased expression of and results in increased activity of HMOX1 protein; KEAP1 protein inhibits the reaction [Curcumin results in increased expression of HMOX1 mRNA]; NFE2L2 gene mutant form affects the reaction [Curcumin promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 protein]]; NFE2L2 gene mutant form inhibits the reaction [Curcumin promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 mRNA]]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of HMOX1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Curcumin results in increased expression of HMOX1 mRNA]; Wortmannin inhibits the reaction [Curcumin results in increased expression of HMOX1 mRNA]; Wortmannin inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]
Curcumin analog results in increased expression of HMOX1 mRNA; Curcumin analog results in increased expression of HMOX1 protein; Curcumin results in increased expression of HMOX1; Curcumin results in increased expression of HMOX1 mRNA; Curcumin results in increased expression of HMOX1 protein
HMOX1 protein results in decreased susceptibility to Curcumin
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein]]; [Curcumin co-treated with Fructose] results in increased expression of HMOX1 protein; [Sitagliptin Phosphate co-treated with Curcumin] inhibits the reaction [decamethrin results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [Acetaminophen results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of HMOX1 mRNA]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [Atrazine results in increased activity of HMOX1 protein]; Curcumin inhibits the reaction [decamethrin results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [Ethanol results in decreased activity of HMOX1 protein]; Curcumin inhibits the reaction [Ketamine results in decreased expression of HMOX1 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [Paraquat results in increased activity of HMOX1 protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Curcumin inhibits the reaction [Thioacetamide results in decreased expression of HMOX1 mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of HMOX1 protein]; Curcumin promotes the reaction [Diethylhexyl Phthalate results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]; Curcumin promotes the reaction [Sildenafil Citrate results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [Sildenafil Citrate results in increased expression of HMOX1 protein]; Curcumin results in increased expression of and results in increased activity of HMOX1 protein; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in decreased expression of HMOX1 mRNA]]; Quartz promotes the reaction [Curcumin results in increased expression of HMOX1 mRNA]; tin protoporphyrin IX inhibits the reaction [Curcumin results in increased activity of HMOX1 protein]		 CTD PMID:10925121 PMID:14742295 PMID:17464175 PMID:17535857 PMID:17627722 More... NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 decreases expression ISO Curcumin results in decreased expression of HNRNPA1 mRNA CTD PMID:17999991 NCBI chr15:103,148,840...103,155,119
Ensembl chr15:103,148,859...103,155,119 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D decreases expression ISO Curcumin results in decreased expression of HNRNPD mRNA CTD PMID:17999991 NCBI chr 5:100,103,794...100,126,926
Ensembl chr 5:100,103,794...100,126,797 		JBrowse link
G Hopx HOP homeobox increases expression ISO Curcumin results in increased expression of HOPX mRNA CTD PMID:18299980 NCBI chr 5:77,234,831...77,262,970
Ensembl chr 5:77,234,835...77,262,968 		JBrowse link
G Hoxb5 homeobox B5 increases expression ISO Curcumin results in increased expression of HOXB5 mRNA CTD PMID:18421014 NCBI chr11:96,194,338...96,196,947
Ensembl chr11:96,194,162...96,196,947 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression ISO Curcumin results in increased expression of HPRT1 mRNA CTD PMID:16101141 NCBI chr  X:52,076,955...52,110,537
Ensembl chr  X:52,077,014...52,110,536 		JBrowse link
G Hsf1 heat shock factor 1 multiple interactions ISO Curcumin promotes the reaction [HSF1 protein binds to HSF1 protein]
[arsenite co-treated with Curcumin] results in increased phosphorylation of HSF1 protein		 CTD PMID:9764755 PMID:11322385 NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113 		JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 decreases expression ISO Curcumin analog results in decreased expression of HSP90AA1 mRNA CTD PMID:26409325 NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 multiple interactions ISO Curcumin promotes the reaction [Diethylhexyl Phthalate results in increased expression of HSP90AB1 mRNA] CTD PMID:26361869 NCBI chr17:45,878,704...45,884,187
Ensembl chr17:45,878,701...45,884,197 		JBrowse link
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 decreases expression ISO Curcumin analog results in decreased expression of HSP90B1 mRNA CTD PMID:26409325 NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373 		JBrowse link
G Hspa1a heat shock protein 1A increases expression
multiple interactions
decreases expression		 ISO Curcumin results in increased expression of HSPA1A mRNA; Curcumin results in increased expression of HSPA1A protein
Curcumin promotes the reaction [Diethylhexyl Phthalate results in increased expression of HSPA1A mRNA]
Curcumin results in decreased expression of HSPA1A protein		 CTD PMID:23555722 PMID:26361869 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132 		JBrowse link
G Hspa4 heat shock protein 4 increases expression ISO Curcumin results in increased expression of HSPA4 mRNA; Curcumin results in increased expression of HSPA4 protein CTD PMID:11322385 NCBI chr11:53,150,641...53,191,306
Ensembl chr11:53,150,641...53,191,284 		JBrowse link
G Hspa5 heat shock protein 5 increases expression
decreases expression
multiple interactions		 EXP
ISO		 Curcumin results in increased expression of HSPA5 mRNA
Curcumin results in decreased expression of HSPA5 protein
4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased expression of HSPA5 protein]; Curcumin inhibits the reaction [Furazolidone results in increased expression of HSPA5 protein]; Curcumin inhibits the reaction [Tunicamycin results in increased expression of HSPA5 protein]		 CTD PMID:18200517 PMID:27996348 PMID:29723631 PMID:36640941 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hspb1 heat shock protein 1 multiple interactions ISO Curcumin inhibits the reaction [Streptozocin results in increased expression of HSPB1 protein]; Curcumin promotes the reaction [Isoproterenol results in increased expression of HSPB1 protein] CTD PMID:18204486 PMID:20125031 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417 		JBrowse link
G Hspb7 heat shock protein family, member 7 (cardiovascular) multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of HSPB7 mRNA] CTD PMID:18200517 NCBI chr 4:141,148,090...141,152,621
Ensembl chr 4:141,148,090...141,152,622 		JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) multiple interactions ISO Curcumin promotes the reaction [Diethylhexyl Phthalate results in increased expression of HSPD1 mRNA]
[arsenic trioxide co-treated with Curcumin] results in increased expression of HSPD1 protein		 CTD PMID:26361869 PMID:27430728 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402 		JBrowse link
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A affects expression ISO Curcumin affects the expression of HTR1A mRNA CTD PMID:17617388 NCBI chr13:105,580,040...105,584,630
Ensembl chr13:105,580,147...105,584,630 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression
affects expression		 ISO
EXP		 [Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]] which results in increased expression of HMOX1 protein; chromium mesoporphyrin inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of ICAM1 protein]; Curcumin inhibits the reaction [Particulate Matter results in increased expression of ICAM1 protein]; Curcumin inhibits the reaction [titanium dioxide results in increased expression of ICAM1 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]
Curcumin analog inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]; Curcumin inhibits the reaction [Methotrexate results in increased expression of ICAM1 mRNA]; ICAM1 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL10 protein]]; ICAM1 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL6 protein]]; ICAM1 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of TNF protein]]; ICAM1 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of CDH2 protein]]; ICAM1 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]; ICAM1 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]]
[chromium mesoporphyrin inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]]] which results in increased expression of HMOX1 protein; [Curcumin co-treated with Gemcitabine] results in decreased expression of ICAM1 protein; [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]] which results in increased expression of HMOX1 protein; chromium mesoporphyrin inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ICAM1 mRNA]
Curcumin results in decreased expression of ICAM1 protein
Curcumin affects the expression of ICAM1 mRNA		 CTD PMID:16219905 PMID:16243823 PMID:17440100 PMID:17666914 PMID:17973899 More... NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO Curcumin results in decreased expression of ID1 mRNA CTD PMID:21594647 NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330 		JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression ISO Curcumin results in decreased expression of ID2 mRNA CTD PMID:21594647 NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139 		JBrowse link
G Id3 inhibitor of DNA binding 3 decreases expression ISO Curcumin results in decreased expression of ID3 mRNA CTD PMID:21594647 NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 decreases expression ISO Curcumin results in decreased expression of IDO1 mRNA CTD PMID:18348204 NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025 		JBrowse link
G Ifna1 interferon alpha 1 multiple interactions ISO Curcumin inhibits the reaction [IFNA1 protein results in increased expression of IFNAR2 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IFNA1 mRNA]; Curcumin promotes the reaction [IFNA1 protein results in increased expression of IFNAR1 protein]; Curcumin promotes the reaction [IFNA1 protein results in increased expression of IL10 protein] CTD PMID:17979888 PMID:23452621 NCBI chr 4:88,768,324...88,768,893
Ensembl chr 4:88,768,324...88,768,893 		JBrowse link
G Ifnar1 interferon (alpha and beta) receptor 1 multiple interactions ISO Curcumin promotes the reaction [IFNA1 protein results in increased expression of IFNAR1 protein]; Curcumin promotes the reaction [IFNB1 protein results in increased expression of IFNAR1 protein] CTD PMID:17979888 NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329 		JBrowse link
G Ifnar2 interferon (alpha and beta) receptor 2 multiple interactions ISO Curcumin inhibits the reaction [IFNA1 protein results in increased expression of IFNAR2 protein]; Curcumin promotes the reaction [IFNB1 protein results in increased expression of IFNAR2 protein] CTD PMID:17979888 NCBI chr16:91,166,517...91,202,477
Ensembl chr16:91,169,671...91,202,477 		JBrowse link
G Ifnb1 interferon beta 1, fibroblast multiple interactions ISO Curcumin promotes the reaction [IFNB1 protein results in increased expression of IFNAR1 protein]; Curcumin promotes the reaction [IFNB1 protein results in increased expression of IFNAR2 protein]; Curcumin promotes the reaction [IFNB1 protein results in increased expression of IL10 protein]; Curcumin promotes the reaction [IFNB1 protein results in increased phosphorylation of STAT4 protein] CTD PMID:17979888 NCBI chr 4:88,440,253...88,441,083
Ensembl chr 4:88,440,262...88,441,011 		JBrowse link
G Ifng interferon gamma multiple interactions
increases secretion		 ISO
EXP		 Curcumin inhibits the reaction [IFNG protein results in increased expression of and results in increased phosphorylation of STAT1 protein]; Curcumin inhibits the reaction [IFNG protein results in increased expression of and results in increased phosphorylation of STAT3 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IFNG mRNA]
[Curcumin co-treated with piperine] inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; Curcumin inhibits the reaction [sodium arsenite affects the expression of IFNG mRNA]; tin protoporphyrin IX inhibits the reaction [[Curcumin co-treated with piperine] inhibits the reaction [IFNG protein results in increased abundance of Nitrites]]
Curcumin results in increased secretion of IFNG protein
Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of IFNG protein]; Curcumin inhibits the reaction [Doxorubicin results in increased expression of IFNG protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of IFNG protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IFNG protein]		 CTD PMID:16782535 PMID:16867261 PMID:16959222 PMID:18006644 PMID:22714040 More... NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Ifnk interferon kappa decreases expression ISO Curcumin results in decreased expression of IFNK mRNA CTD PMID:18421014 NCBI chr 4:35,152,055...35,154,019
Ensembl chr 4:35,152,056...35,154,005 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases activity
multiple interactions
decreases expression
decreases secretion		 ISO
EXP		 Curcumin results in decreased activity of IGF1 protein
Curcumin inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein]; Curcumin inhibits the reaction [IGF1 protein results in increased activity of IGF1R protein]
Curcumin analog results in decreased expression of IGF1 mRNA
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 mRNA]
Curcumin results in decreased secretion of IGF1 protein		 CTD PMID:17458902 PMID:17499312 PMID:18200517 PMID:26409325 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Igf1r insulin-like growth factor I receptor multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [IGF1 protein results in increased activity of IGF1R protein]; Curcumin promotes the reaction [Folfox protocol results in decreased phosphorylation of and results in decreased activity of IGF1R protein]; Curcumin results in decreased phosphorylation of and results in decreased activity of IGF1R protein; Fluorouracil promotes the reaction [Curcumin results in decreased phosphorylation of and results in decreased activity of IGF1R protein]
Curcumin analog results in decreased expression of IGF1R mRNA; Curcumin results in decreased expression of IGF1R mRNA		 CTD PMID:17499312 PMID:17918158 PMID:26409325 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416 		JBrowse link
G Igf2 insulin-like growth factor 2 decreases expression
multiple interactions		 ISO Curcumin analog results in decreased expression of IGF2 mRNA
[arsenic trioxide co-treated with Curcumin] results in increased expression of IGF2 protein		 CTD PMID:26409325 PMID:27430728 NCBI chr 7:142,204,505...142,220,566
Ensembl chr 7:142,204,503...142,220,553 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO [arsenic trioxide co-treated with Curcumin] results in decreased expression of IGFBP1 protein CTD PMID:27430728 NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 multiple interactions ISO [arsenic trioxide co-treated with Curcumin] results in decreased expression of IGFBP2 protein CTD PMID:27430728 NCBI chr 1:72,863,650...72,891,633
Ensembl chr 1:72,863,662...72,891,633 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression
multiple interactions
increases secretion
increases expression		 ISO Curcumin results in decreased expression of IGFBP3 mRNA
[arsenic trioxide co-treated with Curcumin] results in increased expression of IGFBP3 protein
Curcumin results in increased secretion of IGFBP3 protein
Curcumin results in increased expression of IGFBP3 mRNA		 CTD PMID:16101141 PMID:17499312 PMID:18299980 PMID:21594647 PMID:27430728 NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions EXP
ISO		 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGFBP4 mRNA]
[arsenic trioxide co-treated with Curcumin] results in increased expression of IGFBP4 protein		 CTD PMID:18200517 PMID:27430728 NCBI chr11:98,930,820...98,943,481
Ensembl chr11:98,932,070...98,945,218 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions EXP
ISO		 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGFBP5 mRNA]
[arsenic trioxide co-treated with Curcumin] results in increased expression of IGFBP5 protein		 CTD PMID:18200517 PMID:27430728 NCBI chr 1:72,897,224...72,914,024
Ensembl chr 1:72,897,091...72,914,043 		JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 increases expression ISO Curcumin results in increased expression of IGFBP7 mRNA CTD PMID:21594647 NCBI chr 5:77,497,092...77,555,892
Ensembl chr 5:77,497,087...77,555,888 		JBrowse link
G Igll1 immunoglobulin lambda-like polypeptide 1 decreases expression ISO Curcumin results in decreased expression of IGLL1 mRNA CTD PMID:17198877 NCBI chr16:16,678,535...16,681,849
Ensembl chr16:16,678,535...16,681,849 		JBrowse link
G Ikbkb inhibitor of kappaB kinase beta multiple interactions
decreases activity		 ISO
EXP		 Curcumin inhibits the reaction [bisphenol A results in increased expression of IKBKB protein modified form]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IKBKB mRNA]; Curcumin inhibits the reaction [TNF protein results in increased activity of IKBKB protein]; IKBKB protein inhibits the reaction [Curcumin results in decreased expression of CCN2 mRNA]
Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein]
Curcumin results in decreased activity of IKBKB protein		 CTD PMID:16023083 PMID:16219905 PMID:16678799 PMID:17965732 PMID:20054000 More... NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605 		JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IKBKG mRNA] CTD PMID:23452621 NCBI chr  X:73,436,883...73,498,013
Ensembl chr  X:73,436,896...73,497,460 		JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression		 ISO
EXP		 Curcumin inhibits the reaction [nickel chloride results in increased expression of IL10 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IL10 mRNA]; Curcumin promotes the reaction [IFNA1 protein results in increased expression of IL10 protein]; Curcumin promotes the reaction [IFNB1 protein results in increased expression of IL10 protein]
Curcumin results in decreased expression of IL10 protein
CD40 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL10 protein]]; Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL10 protein]; Curcumin analog inhibits the reaction [Copper Sulfate results in decreased secretion of IL10 protein]; Curcumin inhibits the reaction [Copper Sulfate results in decreased secretion of IL10 protein]; Curcumin inhibits the reaction [Methotrexate results in decreased secretion of IL10 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA]; ICAM1 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL10 protein]]		 CTD PMID:15604057 PMID:16867261 PMID:17979888 PMID:20885979 PMID:21397623 More... NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il12a interleukin 12a multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IL12A mRNA] CTD PMID:23452621 NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880 		JBrowse link
G Il12b interleukin 12b multiple interactions ISO Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL12B mRNA]
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IL12B mRNA]		 CTD PMID:16867261 PMID:23452621 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860 		JBrowse link
G Il17a interleukin 17A multiple interactions EXP Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL17A protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of IL17A mRNA] CTD PMID:34998855 PMID:35716765 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720 		JBrowse link
G Il18 interleukin 18 multiple interactions
decreases expression		 ISO
EXP		 Curcumin inhibits the reaction [IL18 protein results in increased expression of VEGFA mRNA]; Curcumin inhibits the reaction [IL18 protein results in increased expression of VEGFA protein]; Curcumin inhibits the reaction [Lipopolysaccharides promotes the reaction [NFKB1 protein binds to IL18 promoter]]; Curcumin inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to IL18 promoter]]
Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of IL18 mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased secretion of IL18 protein]
Curcumin results in decreased expression of IL18 mRNA
Curcumin results in decreased expression of IL18 mRNA; Curcumin results in decreased expression of IL18 protein		 CTD PMID:16368150 PMID:16751071 PMID:17399992 PMID:35063475 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP
ISO		 Curcumin inhibits the reaction [IL1A protein results in increased expression of TNFSF11 protein]
Curcumin inhibits the reaction [Soot results in increased secretion of IL1A protein]		 CTD PMID:18719352 PMID:19782127 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1b interleukin 1 beta affects expression
multiple interactions
decreases expression		 EXP
ISO		 Curcumin affects the expression of IL1B mRNA
Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased phosphorylation of MAPK14 protein]; Curcumin inhibits the reaction [IL1B protein promotes the reaction [Shiga Toxin binds to globotriaosylceramide]]; Curcumin inhibits the reaction [IL1B protein results in decreased expression of GSK3B mRNA]; Curcumin inhibits the reaction [IL1B protein results in decreased expression of ITGB1 protein]; Curcumin inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [IL1B protein results in increased expression of A4GALT mRNA]; Curcumin inhibits the reaction [IL1B protein results in increased expression of CTNNB1 protein]; Curcumin inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [IL1B protein results in increased expression of GSK3B protein]; Curcumin inhibits the reaction [IL1B protein results in increased expression of MMP9 protein]; Curcumin inhibits the reaction [IL1B protein results in increased expression of PTGES protein]; Curcumin inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Curcumin inhibits the reaction [IL1B protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; Curcumin inhibits the reaction [IL1B protein results in increased phosphorylation of and results in increased activity of and results in increased localization of RELA protein]; Curcumin inhibits the reaction [IL1B protein results in increased phosphorylation of NFKBIA protein]; Curcumin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL1B protein]; Curcumin inhibits the reaction [nickel chloride results in increased expression of IL1B protein]; Curcumin inhibits the reaction [TNF protein results in decreased expression of IL1B mRNA]
[Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B mRNA]; [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B protein]; Curcumin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased secretion of IL1B protein]; Curcumin inhibits the reaction [Chloranil results in increased expression of IL1B protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [Dibutyl Phthalate results in increased expression of IL1B protein]; Curcumin inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in decreased expression of IL1B mRNA]
[Sitagliptin Phosphate co-treated with Curcumin] inhibits the reaction [decamethrin results in increased expression of IL1B protein]; Curcumin analog inhibits the reaction [Monocrotaline results in increased expression of IL1B protein]; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased secretion of CXCL2 protein]; Curcumin inhibits the reaction [Acetaminophen results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B protein]; Curcumin inhibits the reaction [decamethrin results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Ethanol results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [Soot results in increased secretion of IL1B protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in increased expression of IL1B protein]]		 CTD PMID:15604057 PMID:15793857 PMID:16751071 PMID:16782535 PMID:16819191 More... NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO
EXP		 Curcumin results in decreased expression of and results in decreased secretion of IL2 protein CTD PMID:19761891 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108 		JBrowse link
G Il2ra interleukin 2 receptor, alpha chain multiple interactions ISO Curcumin inhibits the reaction [Carbon Tetrachloride results in decreased expression of IL2RA protein] CTD PMID:18340409 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004 		JBrowse link
G Il4 interleukin 4 multiple interactions
decreases expression		 ISO
EXP		 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL4 protein]
Curcumin results in decreased expression of IL4 protein		 CTD PMID:16782535 PMID:16867261 PMID:21397623 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il5 interleukin 5 multiple interactions EXP [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL5 protein]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL5 protein] CTD PMID:34998855 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
increases expression
affects expression		 ISO
EXP		 Curcumin inhibits the reaction [[benz(a)anthracene co-treated with TNF protein] results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Acids results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Acids results in increased secretion of IL6 protein]; Curcumin inhibits the reaction [bisphenol A results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased expression of IL6 protein]; Curcumin inhibits the reaction [cadmium sulfate results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [cadmium sulfate results in increased secretion of IL6 protein]; Curcumin inhibits the reaction [IL6 protein results in increased expression of AR mRNA]; Curcumin inhibits the reaction [IL6 protein results in increased expression of AR protein]; Curcumin inhibits the reaction [IL6 protein results in increased expression of KLK3 mRNA]; Curcumin inhibits the reaction [IL6 protein results in increased expression of KLK3 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of IL6 protein]; Curcumin inhibits the reaction [nickel chloride results in increased expression of IL6 protein]; Curcumin inhibits the reaction [TNF protein results in decreased expression of IL6 mRNA]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of IL6 protein]]; SIRT6 protein promotes the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of IL6 protein]]; tin protoporphyrin IX inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]
[Curcumin co-treated with Niacin co-treated with ZM 241385] inhibits the reaction [Rotenone results in increased expression of IL6 protein]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Chloranil results in increased expression of IL6 protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Curcumin inhibits the reaction [Rotenone results in increased expression of IL6 protein]; Curcumin inhibits the reaction [sodium arsenite affects the expression of IL6 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL6 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in decreased expression of IL6 mRNA]
Curcumin results in increased expression of IL6 protein
Curcumin results in increased expression of IL6 mRNA
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; [Sitagliptin Phosphate co-treated with Curcumin] inhibits the reaction [decamethrin results in increased expression of IL6 protein]; [Zinc binds to Curcumin] inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]; CD40 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL6 protein]]; Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL6 protein]; Curcumin analog inhibits the reaction [Glucose results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of IL6 protein]; Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with Tobacco Smoke Pollution] results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Acetaminophen results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Colistin results in increased expression of IL6 protein]; Curcumin inhibits the reaction [decamethrin results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Rotenone results in increased expression of IL6 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Soot results in increased secretion of IL6 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; ICAM1 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL6 protein]]
Curcumin affects the expression of IL6 mRNA; Curcumin affects the expression of IL6 protein		 CTD PMID:16751071 PMID:17151092 PMID:17273796 PMID:17383825 PMID:17999991 More... NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Il6ra interleukin 6 receptor, alpha multiple interactions ISO Curcumin inhibits the reaction [Trichloroethylene results in increased expression of IL6R protein] CTD PMID:34233590 NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503 		JBrowse link
G Il6st interleukin 6 signal transducer multiple interactions ISO Curcumin inhibits the reaction [Trichloroethylene results in increased expression of IL6ST protein] CTD PMID:34233590 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620 		JBrowse link
G Ins1 insulin I multiple interactions EXP
ISO		 Curcumin inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]
Curcumin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]		 CTD PMID:23267840 PMID:25541178 PMID:27208389 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914 		JBrowse link
G Ins2 insulin II multiple interactions ISO
EXP		 Curcumin inhibits the reaction [Fructose results in increased expression of INS protein]
Curcumin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased abundance of Triglycerides]; Curcumin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]; Curcumin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]; Curcumin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]; Curcumin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased abundance of Triglycerides]]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ADIPOQ mRNA]]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CEBPA mRNA]]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of TNF mRNA]]		 CTD PMID:25268984 PMID:26713546 PMID:28595985 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Insig2 insulin induced gene 2 multiple interactions ISO Curcumin inhibits the reaction [INSIG2 protein results in decreased expression of LDLR mRNA] CTD PMID:18704882 NCBI chr 1:121,232,082...121,260,391
Ensembl chr 1:121,232,082...121,260,318 		JBrowse link
G Insr insulin receptor multiple interactions ISO Curcumin inhibits the reaction [bisphenol A results in decreased expression of INSR protein modified form] CTD PMID:29793316 NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617 		JBrowse link
G Irag2 inositol 1,4,5-triphosphate receptor associated 2 decreases expression ISO Curcumin results in decreased expression of IRAG2 mRNA CTD PMID:17198877 NCBI chr 6:145,061,357...145,120,655
Ensembl chr 6:145,061,379...145,120,660 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions EXP
ISO		 Curcumin inhibits the reaction [Lipopolysaccharides results in increased degradation of IRAK1 protein]
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IRAK1 mRNA]		 CTD PMID:16678799 PMID:23452621 NCBI chr  X:73,057,520...73,067,527
Ensembl chr  X:73,057,520...73,067,524 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IRAK2 mRNA] CTD PMID:23452621 NCBI chr 6:113,615,428...113,671,987
Ensembl chr 6:113,615,428...113,671,987 		JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions EXP Curcumin inhibits the reaction [[Lipopolysaccharides binds to TLR4 protein] which results in increased activity of IRF3 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased activity of IRF3 protein] CTD PMID:16678799 NCBI chr 7:44,647,072...44,652,272
Ensembl chr 7:44,647,072...44,652,272 		JBrowse link
G Irf5 interferon regulatory factor 5 increases expression ISO Curcumin analog results in increased expression of IRF5 mRNA CTD PMID:26409325 NCBI chr 6:29,526,129...29,541,874
Ensembl chr 6:29,526,624...29,541,870 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions
affects phosphorylation		 ISO
EXP		 Curcumin inhibits the reaction [Fructose affects the phosphorylation of IRS1 protein]
Curcumin inhibits the reaction [bisphenol A results in increased expression of IRS1 protein modified form]
Curcumin affects the phosphorylation of IRS1 protein		 CTD PMID:26713546 PMID:27208389 PMID:29793316 NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137 		JBrowse link
G Irs2 insulin receptor substrate 2 affects phosphorylation EXP Curcumin affects the phosphorylation of IRS2 protein CTD PMID:27208389 NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458 		JBrowse link
G Itga2b integrin alpha 2b multiple interactions ISO Curcumin inhibits the reaction [F2 protein results in increased expression of ITGA2B protein] CTD PMID:18565277 NCBI chr11:102,344,134...102,360,570
Ensembl chr11:102,344,123...102,360,948 		JBrowse link
G Itgam integrin alpha M multiple interactions
increases expression		 ISO Calcitriol promotes the reaction [Curcumin results in increased expression of ITGAM]; Tretinoin promotes the reaction [Curcumin results in increased expression of ITGAM] CTD PMID:9112257 NCBI chr 7:127,661,812...127,717,663
Ensembl chr 7:127,661,812...127,717,663 		JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [IL1B protein results in decreased expression of ITGB1 protein]
Curcumin results in increased expression of ITGB1 protein		 CTD PMID:17291458 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681 		JBrowse link
G Itgb3 integrin beta 3 multiple interactions ISO Curcumin inhibits the reaction [F2 protein results in increased expression of ITGB3 protein] CTD PMID:18565277 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302 		JBrowse link
G Itm2a integral membrane protein 2A multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of ITM2A mRNA] CTD PMID:18200517 NCBI chr  X:106,440,801...106,446,966
Ensembl chr  X:106,440,705...106,446,982 		JBrowse link
G Ivl involucrin multiple interactions ISO Curcumin inhibits the reaction [MAP3K1 protein results in increased expression of IVL mRNA]; Curcumin inhibits the reaction [PRKCD protein results in increased expression of IVL mRNA]; Curcumin inhibits the reaction [PRKCE protein results in increased expression of IVL mRNA]; Curcumin inhibits the reaction [PRKCH protein results in increased expression of IVL mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IVL mRNA] CTD PMID:17148446 NCBI chr 3:92,478,206...92,481,097
Ensembl chr 3:92,478,209...92,481,042 		JBrowse link
G Jak2 Janus kinase 2 decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of JAK2 protein
Arsenic Trioxide promotes the reaction [Curcumin results in decreased expression of JAK2 protein]; Curcumin inhibits the reaction [Trichloroethylene results in increased phosphorylation of JAK2 protein]		 CTD PMID:16959222 PMID:34233590 PMID:36352148 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480 		JBrowse link
G Jak3 Janus kinase 3 decreases activity ISO Curcumin results in decreased activity of JAK3 protein CTD PMID:16932349 NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219 		JBrowse link
G Jun jun proto-oncogene decreases phosphorylation
multiple interactions
increases expression
decreases activity		 ISO
EXP		 Curcumin results in decreased phosphorylation of JUN protein
Curcumin inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein]; Curcumin inhibits the reaction [benzyl isothiocyanate results in increased expression of and results in increased phosphorylation of JUN protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of JUN mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]
Curcumin inhibits the reaction [Bleomycin results in increased phosphorylation of JUN protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of JUN protein]; Curcumin inhibits the reaction [Tobacco Smoke Pollution results in increased phosphorylation of JUN protein]
Curcumin results in increased expression of JUN mRNA
[Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]; Curcumin analog inhibits the reaction [Rotenone results in increased phosphorylation of JUN protein]
Curcumin results in decreased activity of JUN protein		 CTD PMID:11035063 PMID:15713895 PMID:17148446 PMID:17458902 PMID:17596214 More... NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459 		JBrowse link
G Junb jun B proto-oncogene multiple interactions
increases ubiquitination		 ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]
Curcumin results in increased ubiquitination of JUNB protein		 CTD PMID:17148446 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347 		JBrowse link
G Jund jun D proto-oncogene multiple interactions ISO Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUND protein] CTD PMID:17148446 NCBI chr 8:71,150,389...71,153,265
Ensembl chr 8:71,151,599...71,153,265 		JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO Curcumin results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602 		JBrowse link
G Kcnmb2 potassium large conductance calcium-activated channel, subfamily M, beta member 2 decreases expression ISO Curcumin results in decreased expression of KCNMB2 mRNA CTD PMID:17198877 NCBI chr 3:31,956,021...32,254,329
Ensembl chr 3:31,956,656...32,254,329 		JBrowse link
G Kdr kinase insert domain protein receptor affects expression
multiple interactions		 ISO
EXP		 Curcumin affects the expression of KDR mRNA
[bisdemethoxycurcumin co-treated with Curcumin co-treated with demethoxycurcumin] inhibits the reaction [VEGF protein results in increased phosphorylation of KDR protein]; Curcumin inhibits the reaction [VEGF protein results in increased phosphorylation of KDR protein]
Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of KDR mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of KDR protein]
Curcumin inhibits the reaction [Dietary Fats results in increased expression of KDR mRNA]		 CTD PMID:17960570 PMID:19297423 PMID:23845850 PMID:35752269 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118 		JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions
decreases expression
increases expression		 EXP
ISO		 Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of KEAP1 mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of KEAP1 protein]; KEAP1 protein inhibits the reaction [Curcumin results in increased expression of HMOX1 mRNA]
Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of KEAP1 mRNA]; Curcumin inhibits the reaction [KEAP1 protein results in increased ubiquitination of NFE2L2 protein]
Curcumin results in decreased expression of KEAP1 mRNA
Curcumin analog results in decreased expression of KEAP1 protein; Curcumin results in decreased expression of KEAP1 protein
Curcumin analog promotes the reaction [APP protein modified form results in decreased expression of KEAP1 protein]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of KEAP1 mRNA]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of KEAP1 protein]; Curcumin promotes the reaction [APP protein modified form results in decreased expression of KEAP1 protein]
Curcumin results in increased expression of KEAP1 mRNA		 CTD PMID:17535857 PMID:23710286 PMID:26991801 PMID:30946834 PMID:31521693 More... NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase multiple interactions ISO [Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in increased expression of KIT protein]; [Curcumin binds to carboxymethyl-chitosan analog] which results in decreased expression of KIT protein CTD PMID:26612707 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382 		JBrowse link
G Klf10 Kruppel-like transcription factor 10 decreases expression ISO Curcumin results in decreased expression of KLF10 mRNA CTD PMID:17999991 NCBI chr15:38,291,702...38,300,950
Ensembl chr15:38,291,707...38,300,950 		JBrowse link
G Klf6 Kruppel-like transcription factor 6 increases expression ISO Curcumin results in increased expression of KLF6 mRNA CTD PMID:15713895 NCBI chr13:5,911,488...5,920,392
Ensembl chr13:5,911,481...5,920,393 		JBrowse link
G Klhl21 kelch-like 21 increases expression ISO Curcumin results in increased expression of KLHL21 mRNA CTD PMID:17198877 NCBI chr 4:152,093,348...152,102,134
Ensembl chr 4:152,093,260...152,102,137 		JBrowse link
G Klhl24 kelch-like 24 decreases expression ISO Curcumin results in decreased expression of KLHL24 mRNA CTD PMID:17198877 NCBI chr16:19,916,286...19,947,976
Ensembl chr16:19,916,292...19,947,971 		JBrowse link
G Kmt5a lysine methyltransferase 5A decreases expression ISO Curcumin results in decreased expression of KMT5A mRNA; Curcumin results in decreased expression of KMT5A protein CTD PMID:25256401 NCBI chr 5:124,577,980...124,600,371
Ensembl chr 5:124,577,993...124,600,371 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog decreases expression
multiple interactions		 ISO
EXP		 Curcumin analog results in decreased expression of KRAS mRNA; Curcumin results in decreased expression of KRAS mRNA
Curcumin affects the reaction [KRAS protein affects the localization of TRP53 protein]; Curcumin inhibits the reaction [KRAS protein results in decreased expression of XPO1 protein]		 CTD PMID:17041101 PMID:21519798 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Krtap2-4 keratin associated protein 2-4 decreases expression ISO Curcumin results in decreased expression of KRTAP2-1 mRNA CTD PMID:17999991 NCBI chr11:99,504,843...99,505,672
Ensembl chr11:99,504,845...99,505,672 		JBrowse link
G Kynu kynureninase increases expression ISO Curcumin results in increased expression of KYNU mRNA CTD PMID:18421014 NCBI chr 2:43,445,270...43,572,734
Ensembl chr 2:43,445,341...43,572,734 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 affects expression
multiple interactions		 ISO Curcumin affects the expression of LAMP1 mRNA
Curcumin promotes the reaction [sodium arsenite results in increased expression of LAMP1 protein]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in increased expression of LAMP1 protein]]		 CTD PMID:18539377 PMID:34758851 NCBI chr 8:13,209,161...13,225,338
Ensembl chr 8:13,209,161...13,225,338 		JBrowse link
G Lbp lipopolysaccharide binding protein multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LBP mRNA] CTD PMID:18200517 NCBI chr 2:158,148,413...158,174,772
Ensembl chr 2:158,148,413...158,174,772 		JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP
ISO		 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LCN2 mRNA]
Curcumin inhibits the reaction [Cadmium Chloride results in increased export of LCN2 protein]; Curcumin inhibits the reaction [maleic acid results in increased secretion of LCN2 protein]		 CTD PMID:18200517 PMID:25119790 PMID:29421648 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LCP1 mRNA] CTD PMID:18200517 NCBI chr14:75,368,570...75,468,282
Ensembl chr14:75,368,541...75,468,282 		JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 increases expression ISO Curcumin results in increased expression of LCP2 mRNA CTD PMID:17198877 NCBI chr11:33,996,928...34,042,281
Ensembl chr11:33,996,920...34,042,295 		JBrowse link
G Ldha lactate dehydrogenase A decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of LDHA protein
ATF4 inhibits the reaction [Curcumin results in decreased expression of LDHA protein]; Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of LDHA protein]; Curcumin inhibits the reaction [Sirolimus results in increased expression of LDHA protein]		 CTD PMID:36640941 PMID:36924976 NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051 		JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions
affects expression
increases expression		 ISO
EXP		 Curcumin inhibits the reaction [INSIG2 protein results in decreased expression of LDLR mRNA]; Curcumin results in increased expression of and results in increased activity of LDLR protein
Curcumin affects the expression of LDLR mRNA
Curcumin results in increased expression of LDLR mRNA; Curcumin results in increased expression of LDLR protein		 CTD PMID:16713233 PMID:16963807 PMID:18704882 PMID:27208389 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 increases expression
multiple interactions		 ISO Curcumin results in increased expression of LEF1 mRNA
Curcumin inhibits the reaction [bisphenol A results in decreased expression of LEF1 mRNA]		 CTD PMID:25963729 NCBI chr 3:130,903,972...131,018,006
Ensembl chr 3:130,904,120...131,018,005 		JBrowse link
G Lgmn legumain multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LGMN mRNA] CTD PMID:18200517 NCBI chr12:102,360,341...102,405,987
Ensembl chr12:102,360,343...102,406,072 		JBrowse link
G Lhb luteinizing hormone beta multiple interactions ISO Curcumin inhibits the reaction [sodium arsenite results in decreased expression of LHB protein] CTD PMID:31199764 NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321 		JBrowse link
G Lhx5 LIM homeobox protein 5 affects expression ISO Curcumin affects the expression of LHX5 mRNA CTD PMID:18539377 NCBI chr 5:120,569,951...120,579,522
Ensembl chr 5:120,569,764...120,579,288 		JBrowse link
G Lig3 ligase III, DNA, ATP-dependent multiple interactions ISO Curcumin inhibits the reaction [Arsenic results in decreased expression of LIG3 mRNA]; Curcumin inhibits the reaction [Arsenic results in decreased expression of LIG3 protein] CTD PMID:21332098 NCBI chr11:82,671,977...82,695,100
Ensembl chr11:82,671,934...82,695,100 		JBrowse link
G Lig4 ligase IV, DNA, ATP-dependent multiple interactions ISO Curcumin inhibits the reaction [Arsenic results in decreased expression of LIG4 mRNA]; Curcumin inhibits the reaction [Arsenic results in decreased expression of LIG4 protein] CTD PMID:21332098 NCBI chr 8:10,020,020...10,027,680
Ensembl chr 8:10,019,049...10,027,686 		JBrowse link
G Lipc lipase, hepatic affects expression EXP Curcumin affects the expression of LIPC mRNA CTD PMID:27208389 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508 		JBrowse link
G Lox lysyl oxidase multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LOX mRNA] CTD PMID:18200517 NCBI chr18:52,649,132...52,662,939
Ensembl chr18:52,649,139...52,662,939 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 decreases expression ISO Curcumin results in decreased expression of LPAR1 mRNA CTD PMID:17999991 NCBI chr 4:58,435,252...58,554,601
Ensembl chr 4:58,435,255...58,553,898 		JBrowse link
G Lpl lipoprotein lipase affects expression EXP Curcumin affects the expression of LPL mRNA CTD PMID:27208389 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100 		JBrowse link
G Lrp5 low density lipoprotein receptor-related protein 5 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [bisphenol A results in decreased expression of LRP5 mRNA]
Curcumin results in increased expression of LRP5 mRNA		 CTD PMID:25963729 NCBI chr19:3,634,825...3,736,574
Ensembl chr19:3,634,828...3,736,564 		JBrowse link
G Lrp6 low density lipoprotein receptor-related protein 6 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [bisphenol A results in decreased expression of LRP6 mRNA]
Curcumin results in increased expression of LRP6 mRNA		 CTD PMID:25963729 NCBI chr 6:134,423,439...134,543,876
Ensembl chr 6:134,423,439...134,543,928 		JBrowse link
G Lrrn3 leucine rich repeat protein 3, neuronal increases expression ISO Curcumin results in increased expression of LRRN3 mRNA CTD PMID:17198877 NCBI chr12:41,501,667...41,536,056
Ensembl chr12:41,501,667...41,536,430 		JBrowse link
G Lss lanosterol synthase affects expression
decreases expression		 EXP
ISO		 Curcumin affects the expression of LSS mRNA
Curcumin results in decreased expression of LSS mRNA		 CTD PMID:27208389 NCBI chr10:76,367,303...76,392,973
Ensembl chr10:76,367,422...76,392,972 		JBrowse link
G Lta lymphotoxin A decreases expression
multiple interactions
increases expression		 ISO Curcumin results in decreased expression of LTA mRNA
[arsenic trioxide co-treated with Curcumin] results in increased expression of LTA protein
Curcumin results in increased expression of LTA mRNA		 CTD PMID:16101141 PMID:17198877 PMID:27430728 NCBI chr17:35,422,141...35,424,568
Ensembl chr17:35,422,141...35,424,327 		JBrowse link
G Ltb lymphotoxin B increases expression
decreases expression		 ISO
EXP		 Curcumin results in increased expression of LTB mRNA
Curcumin results in decreased expression of LTB mRNA		 CTD PMID:16751071 PMID:17198877 NCBI chr17:35,413,483...35,415,281
Ensembl chr17:35,413,415...35,415,296 		JBrowse link
G Ltbr lymphotoxin B receptor multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of LTBR mRNA] CTD PMID:23452621 NCBI chr 6:125,283,534...125,291,026
Ensembl chr 6:125,283,534...125,290,848 		JBrowse link
G Lyz1 lysozyme 1 decreases expression EXP Curcumin results in decreased expression of LYZ1 mRNA CTD PMID:19555370 NCBI chr10:117,123,700...117,128,773
Ensembl chr10:117,123,702...117,128,773 		JBrowse link
G Lyz2 lysozyme 2 multiple interactions
affects expression		 EXP
ISO		 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LYZ mRNA]
Curcumin affects the expression of LYZ2 mRNA		 CTD PMID:18200517 PMID:18539377 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MADCAM1 mRNA] CTD PMID:18200517 NCBI chr10:79,500,393...79,504,376
Ensembl chr10:79,500,393...79,504,371 		JBrowse link
G Maoa monoamine oxidase A multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MAOA mRNA] CTD PMID:18200517 NCBI chr  X:16,485,937...16,554,051
Ensembl chr  X:16,485,937...16,554,057 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
decreases expression
increases expression
increases lipidation		 ISO
EXP		 3-methyladenine inhibits the reaction [Curcumin results in increased lipidation of MAP1LC3B protein]; 4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased expression of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [Curcumin results in increased lipidation of MAP1LC3B protein]; Curcumin inhibits the reaction [4-phenylbutyric acid results in decreased expression of MAP1LC3B protein]; Curcumin inhibits the reaction [Sirolimus results in increased expression of MAP1LC3B protein]; Curcumin inhibits the reaction [Tunicamycin results in increased expression of MAP1LC3B protein]; Sirolimus promotes the reaction [Curcumin results in increased lipidation of MAP1LC3B protein]; U 0126 inhibits the reaction [Curcumin results in increased lipidation of MAP1LC3B protein]
Curcumin results in increased expression of MAP1LC3B mRNA		 CTD PMID:34634291 PMID:36640941 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499 		JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 multiple interactions ISO MAP2K1 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]]; MAP2K1 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]]; MAP2K1 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK3 protein]]; MAP2K1 results in decreased susceptibility to [Curcumin co-treated with Mitomycin] CTD PMID:21810436 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913 		JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 multiple interactions ISO MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]]; MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]]; MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK3 protein]]; MAP2K2 results in decreased susceptibility to [Curcumin co-treated with Mitomycin] CTD PMID:21810436 NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809 		JBrowse link
G Map2k3 mitogen-activated protein kinase kinase 3 increases expression ISO Curcumin results in increased expression of MAP2K3 mRNA CTD PMID:15713895 NCBI chr11:60,822,880...60,843,637
Ensembl chr11:60,822,859...60,843,637 		JBrowse link
G Map2k4 mitogen-activated protein kinase kinase 4 decreases expression
increases phosphorylation		 ISO Curcumin results in decreased expression of MAP2K4 mRNA
Curcumin increases phosphorylation of MAP2K4 protein in uterine cervix		 CTD
RGD		 PMID:15713895 PMID:25198898 RGD:150429751 NCBI chr11:65,579,070...65,679,185
Ensembl chr11:65,579,069...65,679,123 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [MAP3K1 protein results in increased expression of IVL mRNA]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of MAP3K1 mRNA]
Curcumin results in decreased expression of MAP3K1 mRNA		 CTD PMID:15713895 PMID:17148446 PMID:23452621 NCBI chr13:111,882,962...111,954,803
Ensembl chr13:111,882,962...111,945,527 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 increases phosphorylation ISO Curcumin increases phosphorylation of MAP3K5 protein in uterine cervix RGD PMID:25198898 RGD:150429751 NCBI chr10:19,809,847...20,018,496
Ensembl chr10:19,810,218...20,018,499 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation
increases phosphorylation
decreases expression
decreases activity		 ISO
EXP		 [bisdemethoxycurcumin co-treated with Curcumin co-treated with demethoxycurcumin] inhibits the reaction [VEGF protein results in increased phosphorylation of MAPK1 protein]; [Curcumin results in decreased activity of MAPK1 protein] which results in increased susceptibility to Cisplatin; [ERBB2 protein results in increased susceptibility to Curcumin analog] which results in decreased phosphorylation of MAPK1 protein; Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of MAPK1 protein]; Arsenic Trioxide promotes the reaction [Curcumin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Bortezomib promotes the reaction [Curcumin results in decreased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Acids results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [bromopyruvate results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Furazolidone results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Nicotine results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [VEGF protein results in increased phosphorylation of MAPK1 protein]; Curcumin results in increased phosphorylation of and results in increased activity of MAPK1 protein; MAP2K1 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]]; MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]]; MAPK1 protein affects the reaction [Curcumin results in increased expression of CDKN1A mRNA]; rottlerin inhibits the reaction [Curcumin results in increased expression of MAPK1 protein]; U 0126 inhibits the reaction [Curcumin results in increased phosphorylation of MAPK1 protein]; U 0126 promotes the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK1 protein]]
Curcumin inhibits the reaction [Corticosterone results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Fructose results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK1 protein]; Curcumin results in decreased phosphorylation of and results in decreased activity of MAPK1 protein; tin protoporphyrin IX inhibits the reaction [Curcumin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]]
[Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; [piperlongumine co-treated with Curcumin] results in decreased activity of MAPK1 protein; Curcumin inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Tobacco Smoke Pollution results in increased phosphorylation of MAPK1 protein]
Curcumin results in decreased expression of MAPK1 protein		 CTD PMID:11035063 PMID:11981161 PMID:16934299 PMID:17372590 PMID:17535857 More... NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk10 mitogen-activated protein kinase 10 multiple interactions ISO Curcumin analog inhibits the reaction [Rotenone results in increased phosphorylation of MAPK10 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of MAPK10 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK10 protein] CTD PMID:24952339 PMID:27535828 PMID:27966075 NCBI chr 5:103,056,413...103,359,200
Ensembl chr 5:103,055,814...103,359,200 		JBrowse link
G Mapk12 mitogen-activated protein kinase 12 increases activity ISO Curcumin results in increased activity of MAPK12 protein CTD PMID:21594647 NCBI chr15:89,014,787...89,025,270
Ensembl chr15:89,014,787...89,024,906 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 multiple interactions ISO Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased phosphorylation of MAPK14 protein]; Curcumin inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK14 mRNA]; MAPK14 protein affects the reaction [Curcumin results in increased expression of HMOX1 protein] CTD PMID:17151092 PMID:18357586 PMID:31521693 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation
increases phosphorylation
decreases expression
decreases activity		 ISO
EXP		 [bisdemethoxycurcumin co-treated with Curcumin co-treated with demethoxycurcumin] inhibits the reaction [VEGF protein results in increased phosphorylation of MAPK3 protein]; [Curcumin results in decreased activity of MAPK3 protein] which results in increased susceptibility to Cisplatin; [ERBB2 protein results in increased susceptibility to Curcumin analog] which results in decreased phosphorylation of MAPK3 protein; Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of MAPK3 protein]; Arsenic Trioxide promotes the reaction [Curcumin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Bortezomib promotes the reaction [Curcumin results in decreased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Acids results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [bromopyruvate results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Curcumin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Nicotine results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [VEGF protein results in increased phosphorylation of MAPK3 protein]; Curcumin results in increased phosphorylation of and results in increased activity of MAPK3 protein; MAP2K1 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK3 protein]]; MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK3 protein]]; rottlerin inhibits the reaction [Curcumin results in increased expression of MAPK3 protein]; U 0126 inhibits the reaction [Curcumin results in increased phosphorylation of MAPK3 protein]; U 0126 promotes the reaction [Curcumin inhibits the reaction [Mitomycin results in increased phosphorylation of MAPK3 protein]]
Curcumin inhibits the reaction [Corticosterone results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Fructose results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK3 protein]; Curcumin results in decreased phosphorylation of and results in decreased activity of MAPK3 protein; tin protoporphyrin IX inhibits the reaction [Curcumin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]]
[Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]; [piperlongumine co-treated with Curcumin] results in decreased activity of MAPK3 protein; Curcumin inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [Tobacco Smoke Pollution results in increased phosphorylation of MAPK3 protein]
Curcumin results in decreased expression of MAPK3 protein		 CTD PMID:11035063 PMID:11981161 PMID:16934299 PMID:17372590 PMID:17535857 More... NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
decreases phosphorylation
increases expression		 ISO
EXP		 Curcumin inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK8 mRNA]; Curcumin inhibits the reaction [Nicotine results in increased phosphorylation of MAPK8 protein]; MAPK8 protein affects the reaction [Curcumin results in increased expression of CDKN1A mRNA]
Curcumin increases phosphorylation of MAPK8 protein in uterine cervix
Curcumin results in decreased phosphorylation of MAPK8 protein
Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of MAPK8 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein]; Curcumin inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK8 protein]; Curcumin results in decreased phosphorylation of and results in decreased activity of MAPK8 protein
Curcumin inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK8 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK8 protein]; Curcumin inhibits the reaction [Bleomycin results in increased phosphorylation of MAPK8 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein]
Curcumin results in increased expression of MAPK8 mRNA
Curcumin results in increased phosphorylation of MAPK8 protein		 CTD
RGD		 PMID:11981161 PMID:16101141 PMID:16678799 PMID:16934299 PMID:17372590 More... RGD:150429751 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
decreases phosphorylation
increases phosphorylation		 EXP
ISO		 Curcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK9 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK9 protein]
Curcumin results in decreased phosphorylation of MAPK9 protein
Curcumin results in increased phosphorylation of MAPK9 protein
Curcumin inhibits the reaction [sodium arsenite results in increased expression of MAPK9 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK9 protein]; Curcumin inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK9 protein]; Curcumin results in decreased phosphorylation of and results in decreased activity of MAPK9 protein		 CTD PMID:11981161 PMID:17372590 PMID:18316600 PMID:18321868 PMID:18332871 More... NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248 		JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of MAPT mRNA] CTD PMID:31521693 NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916 		JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 decreases expression
multiple interactions		 EXP
ISO		 Curcumin results in decreased expression of MCL1 protein alternative form
[Curcumin co-treated with Arsenic Trioxide] results in decreased expression of MCL1 protein		 CTD PMID:18829502 PMID:34675983 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 decreases expression ISO Curcumin results in decreased expression of MCM2 mRNA CTD PMID:18299980 NCBI chr 6:88,860,456...88,875,762
Ensembl chr 6:88,860,456...88,875,762 		JBrowse link
G Mcm7 minichromosome maintenance complex component 7 decreases expression ISO Curcumin results in decreased expression of MCM7 mRNA CTD PMID:17198877 NCBI chr 5:138,162,845...138,170,675
Ensembl chr 5:138,162,845...138,170,684 		JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 decreases expression
increases expression
multiple interactions		 ISO [Curcumin results in decreased expression of MDM2 protein] which results in decreased expression of CDKN1A mRNA; Curcumin results in decreased expression of MDM2 mRNA; Curcumin results in decreased expression of MDM2 protein
Curcumin analog results in increased expression of MDM2 mRNA
Curcumin inhibits the reaction [bisphenol A results in increased phosphorylation of MDM2 protein]		 CTD PMID:17332326 PMID:24831732 PMID:26409325 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663 		JBrowse link
G Mecp2 methyl CpG binding protein 2 decreases expression ISO Curcumin results in decreased expression of MECP2 protein CTD PMID:23593078 NCBI chr  X:73,070,198...73,129,296
Ensembl chr  X:73,070,198...73,129,296 		JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression EXP Curcumin results in decreased expression of MEF2C mRNA CTD PMID:27237783 NCBI chr13:83,652,136...83,815,197
Ensembl chr13:83,652,153...83,815,199 		JBrowse link
G Meltf melanotransferrin decreases expression ISO Curcumin results in decreased expression of MELTF mRNA CTD PMID:17198877 NCBI chr16:31,697,449...31,717,838
Ensembl chr16:31,697,628...31,717,838 		JBrowse link
G Mfn1 mitofusin 1 increases expression ISO Curcumin results in increased expression of MFN1 protein CTD PMID:28698153 NCBI chr 3:32,583,594...32,633,384
Ensembl chr 3:32,583,614...32,633,388 		JBrowse link
G Mfng MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase increases expression ISO Curcumin results in increased expression of MFNG mRNA CTD PMID:17198877 NCBI chr15:78,640,082...78,657,678
Ensembl chr15:78,640,082...78,657,675 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases expression
increases expression
decreases activity
multiple interactions		 ISO Curcumin results in decreased expression of MGMT mRNA
Curcumin results in increased expression of MGMT mRNA
Curcumin results in decreased activity of MGMT protein
Curcumin results in increased expression of and results in increased activity of MGMT protein		 CTD PMID:16950796 PMID:17596214 NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO Curcumin results in increased expression of MGST1 mRNA CTD PMID:18299980 NCBI chr 6:138,117,525...138,133,753
Ensembl chr 6:138,117,314...138,133,753 		JBrowse link
G Mir125a microRNA 125a decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of MIR125A mRNA
Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of MIR125A mRNA]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 mRNA]]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 protein]]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CCL2 protein]]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of IL6 protein]]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of TNF protein]]		 CTD PMID:29723631 PMID:33952798 NCBI chr17:18,051,074...18,051,141
Ensembl chr17:18,051,074...18,051,141 		JBrowse link
G Mir146 microRNA 146 multiple interactions ISO Curcumin inhibits the reaction [[ferrous sulfate co-treated with aluminum sulfate] results in increased expression of MIR146A mRNA] CTD PMID:22099153 NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288 		JBrowse link
G Mir19a microRNA 19a multiple interactions ISO Curcumin inhibits the reaction [bisphenol A results in increased expression of MIR19A mRNA] CTD PMID:24831732 NCBI chr14:115,281,432...115,281,513
Ensembl chr14:115,281,432...115,281,513 		JBrowse link
G Mir21a microRNA 21a decreases expression ISO Curcumin results in decreased expression of MIR21 mRNA CTD PMID:29723631 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984 		JBrowse link
G Mir22 microRNA 22 increases expression ISO Curcumin results in increased expression of MIR22 CTD PMID:26244872 NCBI chr11:75,354,542...75,354,636
Ensembl chr11:75,354,542...75,354,636 		JBrowse link
G Mir222 microRNA 222 decreases expression ISO Curcumin results in decreased expression of MIR222 mRNA CTD PMID:29723631 NCBI chr  X:19,013,132...19,013,210
Ensembl chr  X:19,013,132...19,013,210 		JBrowse link
G Mir223 microRNA 223 increases expression ISO Curcumin results in increased expression of MIR223 mRNA CTD PMID:29723631 NCBI chr  X:95,286,423...95,286,532
Ensembl chr  X:95,286,423...95,286,532 		JBrowse link
G Mir22hg Mir22 host gene (non-protein coding) increases expression ISO Curcumin results in increased expression of MIR22HG mRNA CTD PMID:17999991 NCBI chr11:75,352,365...75,357,516
Ensembl chr11:75,352,365...75,357,502 		JBrowse link
G Mir27a microRNA 27a decreases expression ISO Curcumin results in decreased expression of MIR27A mRNA CTD PMID:29723631 NCBI chr 8:84,935,301...84,935,387
Ensembl chr 8:84,935,301...84,935,387 		JBrowse link
G Mir27b microRNA 27b decreases expression ISO Curcumin results in decreased expression of MIR27B mRNA CTD PMID:29723631 NCBI chr13:63,448,526...63,448,598
Ensembl chr13:63,448,526...63,448,598 		JBrowse link
G Mir30a microRNA 30a increases expression ISO Curcumin results in increased expression of MIR30A mRNA CTD PMID:29723631 NCBI chr 1:23,311,350...23,311,420
Ensembl chr 1:23,311,350...23,311,420 		JBrowse link
G Mir34a microRNA 34a multiple interactions ISO Curcumin inhibits the reaction [Cyclosporine results in increased expression of MIR34A mRNA] CTD PMID:32569592 NCBI chr 4:150,152,911...150,153,012
Ensembl chr 4:150,152,911...150,153,012 		JBrowse link
G Mir532 microRNA 532 increases expression
multiple interactions		 ISO Curcumin results in increased expression of MIR532 mRNA
MIR532 affects the reaction [Curcumin results in decreased expression of AKT3 protein]; MIR532 affects the reaction [Curcumin results in decreased phosphorylation of AKT1 protein]; NRIP1 mRNA alternative form inhibits the reaction [Curcumin results in increased expression of MIR532 mRNA]		 CTD PMID:37471645 NCBI chr  X:7,114,641...7,114,736
Ensembl chr  X:7,114,641...7,114,736 		JBrowse link
G Mir802 microRNA 802 multiple interactions ISO Curcumin inhibits the reaction [Acetaminophen results in increased expression of MIR802 mRNA] CTD PMID:33350580 NCBI chr16:93,166,608...93,166,704
Ensembl chr16:93,166,608...93,166,704 		JBrowse link
G Mir99a microRNA 99a multiple interactions ISO Curcumin inhibits the reaction [benzyl isothiocyanate results in increased expression of MIR99A mRNA] CTD PMID:31587482 NCBI chr16:77,395,824...77,395,888
Ensembl chr16:77,395,824...77,395,888 		JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 multiple interactions
decreases expression		 EXP
ISO		 [Curcumin co-treated with Gemcitabine] results in decreased expression of MKI67 protein
Curcumin results in decreased expression of MKI67 protein		 CTD PMID:17440100 PMID:18226269 PMID:19372569 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090 		JBrowse link
G Mme membrane metallo endopeptidase decreases expression ISO Curcumin results in decreased expression of MME mRNA CTD PMID:17198877 NCBI chr 3:63,202,632...63,291,134
Ensembl chr 3:63,148,958...63,293,451 		JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression ISO Curcumin results in increased expression of MMP10 mRNA CTD PMID:15713895 NCBI chr 9:7,502,343...7,510,243
Ensembl chr 9:7,502,353...7,510,241 		JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions ISO Curcumin inhibits the reaction [Chloramphenicol results in increased expression of MMP13 mRNA] CTD PMID:20338993 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331 		JBrowse link
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) decreases expression
multiple interactions		 ISO
EXP		 Curcumin results in decreased expression of MMP14 protein
Curcumin inhibits the reaction [Indomethacin results in decreased expression of MMP14 protein]
Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP14 mRNA]		 CTD PMID:16934674 PMID:18200517 PMID:18495463 NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821 		JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) multiple interactions EXP Curcumin inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA] CTD PMID:30098273 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression
decreases activity
increases activity		 ISO
EXP		 Curcumin inhibits the reaction [4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine results in increased expression of MMP2 protein]; Curcumin inhibits the reaction [Sirolimus results in increased expression of MMP2 protein]; Curcumin inhibits the reaction [VEGFA protein results in increased expression of and results in increased activity of MMP2 protein]; Curcumin inhibits the reaction [VIP protein results in increased activity of MMP2 protein]; Curcumin results in decreased secretion of and results in decreased activity of MMP2 protein modified form; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of MMP2 protein]
Curcumin results in decreased activity of MMP2 protein
Curcumin results in increased activity of MMP2 protein
Curcumin inhibits the reaction [Bleomycin results in increased expression of and results in increased secretion of MMP2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of MMP2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP2 mRNA]
2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in increased activity of MMP2 protein]; Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased activity of MMP2 protein]		 CTD PMID:16934674 PMID:17531121 PMID:17996675 PMID:18200517 PMID:18226269 More... NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO Curcumin results in increased expression of MMP3 mRNA CTD PMID:15713895 PMID:18321735 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975 		JBrowse link
G Mmp7 matrix metallopeptidase 7 multiple interactions ISO Curcumin inhibits the reaction [epigallocatechin gallate results in increased expression of MMP7 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of MMP7 mRNA]; Curcumin inhibits the reaction [Tretinoin results in increased expression of MMP7 mRNA] CTD PMID:17928719 PMID:23452621 NCBI chr 9:7,692,095...7,699,587
Ensembl chr 9:7,692,091...7,699,586 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases activity
decreases expression
increases activity
affects expression		 ISO
EXP		 3-caffeoyl-4-dihydrocaffeoylquinic acid promotes the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine promotes the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine promotes the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]]; Curcumin inhibits the reaction [4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine results in increased expression of MMP9 protein]; Curcumin inhibits the reaction [Cadmium results in increased expression of MMP9 mRNA]; Curcumin inhibits the reaction [IL1B protein results in increased expression of MMP9 protein]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of MMP9 protein]; Curcumin inhibits the reaction [Sirolimus results in increased expression of MMP9 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of MMP9 protein]; Curcumin inhibits the reaction [VIP protein results in increased activity of MMP9 protein]; Curcumin promotes the reaction [3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; Curcumin promotes the reaction [4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; Curcumin promotes the reaction [4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]]; Curcumin results in decreased secretion of and results in decreased activity of MMP9 protein; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of MMP9 protein]]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of MMP9 protein]
Curcumin results in decreased activity of MMP9 protein
Curcumin results in increased activity of MMP9 protein
Curcumin affects the expression of MMP9 mRNA; Curcumin affects the expression of MMP9 protein
2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in increased activity of MMP9 protein]; [Zinc binds to Curcumin] inhibits the reaction [Acetic Acid results in increased expression of MMP9 mRNA]; Curcumin inhibits the reaction [Ethanol results in increased expression of MMP9 mRNA]
[Curcumin co-treated with Gemcitabine] results in decreased expression of MMP9 protein; [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of and results in increased activity of MMP9 protein]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of MMP9 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of and results in increased secretion of MMP9 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]		 CTD PMID:16219905 PMID:16243823 PMID:17291458 PMID:17440100 PMID:17531121 More... NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Mphosph6 M phase phosphoprotein 6 decreases expression ISO Curcumin results in decreased expression of MPHOSPH6 mRNA CTD PMID:18421014 NCBI chr 8:118,518,376...118,528,713
Ensembl chr 8:118,518,384...118,528,682 		JBrowse link
G Mpo myeloperoxidase multiple interactions
decreases activity		 ISO
EXP		 Curcumin inhibits the reaction [Dinitrochlorobenzene results in decreased activity of MPO protein]; Curcumin inhibits the reaction [Indomethacin results in increased activity of MPO protein]; Curcumin inhibits the reaction [Methotrexate results in increased expression of MPO protein]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of MPO protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in increased expression of MPO protein]]
[Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of MPO protein]; chromium mesoporphyrin inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein]]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of MPO protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein]; Curcumin inhibits the reaction [Paraquat results in increased expression of MPO protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of MPO protein]
Curcumin analog results in decreased activity of MPO protein
Curcumin results in decreased activity of MPO protein		 CTD PMID:16804969 PMID:16867261 PMID:17276891 PMID:17351913 PMID:17373747 More... NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Mrpl1 mitochondrial ribosomal protein L1 increases expression ISO Curcumin results in increased expression of MRPL1 mRNA CTD PMID:17198877 NCBI chr 5:96,357,357...96,414,586
Ensembl chr 5:96,357,352...96,414,586 		JBrowse link
G Mrpl47 mitochondrial ribosomal protein L47 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MRPL47 mRNA] CTD PMID:18200517 NCBI chr 3:32,781,646...32,790,904
Ensembl chr 3:32,779,546...32,791,754 		JBrowse link
G Ms4a1 membrane-spanning 4-domains, subfamily A, member 1 decreases expression
increases expression		 ISO Curcumin results in decreased expression of MS4A1 mRNA
Curcumin results in increased expression of MS4A1 mRNA		 CTD PMID:17198877 PMID:18421014 NCBI chr19:11,227,043...11,243,513
Ensembl chr19:11,227,039...11,243,605 		JBrowse link
G Msmo1 methylsterol monoxygenase 1 affects expression
decreases expression		 EXP
ISO		 Curcumin affects the expression of MSMO1 mRNA
Curcumin results in decreased expression of MSMO1 mRNA		 CTD PMID:27208389 NCBI chr 8:65,171,157...65,186,822
Ensembl chr 8:65,171,173...65,186,826 		JBrowse link
G Msn moesin multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MSN mRNA] CTD PMID:18200517 NCBI chr  X:95,139,651...95,212,159
Ensembl chr  X:95,139,648...95,212,158 		JBrowse link
G Msr1 macrophage scavenger receptor 1 multiple interactions ISO Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of MSR1 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA] CTD PMID:23386263 NCBI chr 8:39,996,284...40,095,790
Ensembl chr 8:40,034,726...40,095,714 		JBrowse link
G Mst1r macrophage stimulating 1 receptor (c-met-related tyrosine kinase) multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [RELA protein binds to MST1R promoter]; Curcumin inhibits the reaction [RELA protein results in increased expression of MST1R mRNA]
Curcumin results in decreased expression of MST1R mRNA; Curcumin results in decreased expression of MST1R protein		 CTD PMID:18593918 NCBI chr 9:107,784,057...107,797,582
Ensembl chr 9:107,784,072...107,797,582 		JBrowse link
G Mt2 metallothionein 2 multiple interactions
increases expression		 ISO Curcumin affects the reaction [Mercuric Chloride results in increased expression of MT2A mRNA]
Curcumin results in increased expression of MT2A mRNA		 CTD PMID:20229497 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation
multiple interactions
decreases expression		 ISO
EXP		 Curcumin results in decreased phosphorylation of MTOR protein
ATF4 inhibits the reaction [Curcumin results in decreased phosphorylation of MTOR protein]; Curcumin inhibits the reaction [Thioacetamide results in increased phosphorylation of MTOR protein]
4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased phosphorylation of MTOR protein]; Curcumin analog inhibits the reaction [Oxygen deficiency results in increased phosphorylation of MTOR protein]; Curcumin inhibits the reaction [4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine results in increased phosphorylation of MTOR protein]; Curcumin inhibits the reaction [Tunicamycin results in increased expression of and results in increased phosphorylation of MTOR protein]; Curcumin promotes the reaction [Sirolimus results in decreased phosphorylation of MTOR protein]; Curcumin results in decreased expression of and results in decreased phosphorylation of MTOR protein
Curcumin analog results in decreased expression of MTOR mRNA; Curcumin results in decreased expression of MTOR mRNA		 CTD PMID:20554536 PMID:21450334 PMID:26409325 PMID:27363783 PMID:33582110 More... NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric multiple interactions ISO Curcumin inhibits the reaction [o,p'-DDT results in increased expression of MUC5AC mRNA] CTD PMID:34167450 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968 		JBrowse link
G Mvd mevalonate (diphospho) decarboxylase decreases expression ISO Curcumin results in decreased expression of MVD mRNA CTD PMID:17198877 NCBI chr 8:123,160,335...123,170,161
Ensembl chr 8:123,160,340...123,170,161 		JBrowse link
G Mvk mevalonate kinase affects expression
decreases expression		 EXP
ISO		 Curcumin affects the expression of MVK mRNA
Curcumin results in decreased expression of MVK mRNA		 CTD PMID:27208389 NCBI chr 5:114,582,324...114,598,652
Ensembl chr 5:114,582,330...114,598,652 		JBrowse link
G Mxd1 MAX dimerization protein 1 increases expression ISO Curcumin results in increased expression of MXD1 mRNA CTD PMID:15713895 NCBI chr 6:86,624,026...86,646,099
Ensembl chr 6:86,624,024...86,646,143 		JBrowse link
G Mxd3 Max dimerization protein 3 decreases expression ISO Curcumin results in decreased expression of MXD3 mRNA CTD PMID:15713895 PMID:17198877 NCBI chr13:55,472,983...55,477,937
Ensembl chr13:55,472,981...55,477,636 		JBrowse link
G Myc myelocytomatosis oncogene multiple interactions
increases expression
decreases expression		 ISO
EXP		 [Curcumin co-treated with Doxorubicin] affects the expression of MYC mRNA; Curcumin inhibits the reaction [Paclitaxel results in increased expression of MYC protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of MYC mRNA]
[Curcumin co-treated with Gemcitabine] results in decreased expression of MYC protein
Curcumin results in increased expression of MYC mRNA
Curcumin analog results in decreased expression of MYC protein; Curcumin results in decreased expression of MYC mRNA; Curcumin results in decreased expression of MYC protein		 CTD PMID:15713895 PMID:15911101 PMID:16219905 PMID:16243823 PMID:17041101 More... NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Myd88 myeloid differentiation primary response gene 88 multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of MYD88 mRNA]
Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of MYD88 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MYD88 protein]		 CTD PMID:19002562 PMID:23452621 PMID:34719837 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477 		JBrowse link
G Myh1 myosin, heavy polypeptide 1, skeletal muscle, adult decreases expression ISO Curcumin results in decreased expression of MYH1 mRNA CTD PMID:18299980 NCBI chr11:67,090,922...67,115,401
Ensembl chr11:67,090,878...67,115,401 		JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha decreases expression EXP Curcumin results in decreased expression of MYH6 mRNA CTD PMID:27237783 NCBI chr14:55,179,378...55,205,553
Ensembl chr14:55,179,378...55,204,384 		JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta multiple interactions
decreases expression		 ISO carboxymethyl-chitosan analog promotes the reaction [Curcumin results in decreased expression of MYH7 mRNA]; Curcumin inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA]; Curcumin promotes the reaction [KN 93 inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA]]; KN 93 promotes the reaction [Curcumin inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA]] CTD PMID:25093688 PMID:26612707 NCBI chr14:55,208,141...55,232,083
Ensembl chr14:55,208,141...55,232,083 		JBrowse link
G Myl12a myosin, light chain 12A, regulatory, non-sarcomeric increases expression ISO Curcumin results in increased expression of MYL12A mRNA CTD PMID:17999991 NCBI chr17:71,300,788...71,309,528
Ensembl chr17:71,300,651...71,309,873 		JBrowse link
G Myl4 myosin, light polypeptide 4 decreases expression EXP Curcumin results in decreased expression of MYL4 mRNA CTD PMID:27237783 NCBI chr11:104,427,604...104,478,041
Ensembl chr11:104,441,489...104,486,579 		JBrowse link
G Myl9 myosin, light polypeptide 9, regulatory multiple interactions EXP Curcumin inhibits the reaction [deoxynivalenol results in increased expression of MYL9 protein modified form] CTD PMID:35817260 NCBI chr 2:156,617,373...156,623,578
Ensembl chr 2:156,617,340...156,623,578 		JBrowse link
G Mylk myosin, light polypeptide kinase increases expression
multiple interactions		 ISO
EXP		 Curcumin results in increased expression of MYLK mRNA
Curcumin inhibits the reaction [deoxynivalenol results in increased expression of MYLK mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of MYLK protein]		 CTD PMID:21594647 PMID:35817260 NCBI chr16:34,565,569...34,822,806
Ensembl chr16:34,565,580...34,822,790 		JBrowse link
G Myo18a myosin XVIIIA increases expression ISO Curcumin results in increased expression of MYO18A mRNA CTD PMID:18421014 NCBI chr11:77,654,066...77,756,806
Ensembl chr11:77,654,072...77,756,806 		JBrowse link
G Naip2 NLR family, apoptosis inhibitory protein 2 decreases expression
multiple interactions		 ISO Curcumin analog results in decreased expression of NAIP mRNA; Curcumin results in decreased expression of NAIP mRNA
[Curcumin co-treated with Doxorubicin] affects the expression of NAIP mRNA; [Curcumin co-treated with Oxygen deficiency] results in decreased expression of NAIP protein		 CTD PMID:15911101 PMID:17671737 PMID:19250217 PMID:23452621 NCBI chr13:100,280,571...100,338,630
Ensembl chr13:100,280,571...100,338,600 		JBrowse link
G Nanog Nanog homeobox multiple interactions
increases expression		 EXP 2-methoxyestradiol inhibits the reaction [Curcumin results in increased expression of NANOG mRNA]
Curcumin results in increased expression of NANOG mRNA; Curcumin results in increased expression of NANOG protein		 CTD PMID:25822711 PMID:27237783 NCBI chr 6:122,684,448...122,691,592
Ensembl chr 6:122,684,448...122,691,592 		JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 decreases expression ISO Curcumin results in decreased expression of NANOS1 mRNA CTD PMID:17999991 NCBI chr19:60,744,425...60,748,352
Ensembl chr19:60,744,425...60,748,352 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 increases expression ISO Curcumin results in increased expression of NCAM1 protein modified form CTD PMID:19161989 NCBI chr 9:49,413,434...49,710,909
Ensembl chr 9:49,413,436...49,710,225 		JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Curcumin promotes the reaction [VDR protein binds to NCOA1 protein] CTD PMID:20153625 NCBI chr12:4,297,362...4,569,452
Ensembl chr12:4,297,362...4,527,182 		JBrowse link
G Nefm neurofilament, medium polypeptide increases expression ISO Curcumin results in increased expression of NEFM mRNA CTD PMID:18299980 NCBI chr14:68,356,994...68,362,453
Ensembl chr14:68,320,039...68,362,295 		JBrowse link
G Neil1 nei endonuclease VIII-like 1 (E. coli) multiple interactions ISO Curcumin inhibits the reaction [Copper binds to and results in decreased activity of NEIL1 protein]; Curcumin inhibits the reaction [Iron binds to and results in decreased activity of NEIL1 protein] CTD PMID:20622253 NCBI chr 9:57,050,072...57,055,973
Ensembl chr 9:57,050,084...57,055,589 		JBrowse link
G Nes nestin multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [bisphenol A results in decreased expression of NES mRNA]
Curcumin results in increased expression of NES mRNA		 CTD PMID:25963729 NCBI chr 3:87,878,400...87,887,758
Ensembl chr 3:87,878,385...87,887,758 		JBrowse link
G Neurod1 neurogenic differentiation 1 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [bisphenol A results in decreased expression of NEUROD1 mRNA]
Curcumin results in increased expression of NEUROD1 mRNA		 CTD PMID:25963729 NCBI chr 2:79,282,981...79,286,980
Ensembl chr 2:79,282,865...79,287,095 		JBrowse link
G Neurog1 neurogenin 1 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [bisphenol A results in decreased expression of NEUROG1 mRNA]
Curcumin results in increased expression of NEUROG1 mRNA		 CTD PMID:25963729 NCBI chr13:56,398,291...56,399,993
Ensembl chr13:56,398,291...56,399,976 		JBrowse link
G Nfe2l1 nuclear factor, erythroid derived 2,-like 1 increases expression ISO Curcumin results in increased expression of NFE2L1 protein CTD PMID:23710286 NCBI chr11:96,708,239...96,720,810
Ensembl chr11:96,708,240...96,720,794 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions
increases expression
increases activity
decreases response to substance
decreases methylation
affects localization
increases localization		 ISO
EXP		 [Curcumin co-treated with Acetaminophen] results in increased expression of NFE2L2 mRNA; [Curcumin co-treated with Acetaminophen] results in increased expression of NFE2L2 protein; Curcumin inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein]]; Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [KEAP1 protein results in increased ubiquitination of NFE2L2 protein]; Curcumin promotes the reaction [Furazolidone results in increased expression of NFE2L2 protein]; Curcumin promotes the reaction [NFE2L2 protein binds to GSTP1 promoter]; Curcumin promotes the reaction [NFE2L2 protein results in increased expression of GSTP1 mRNA]; Curcumin promotes the reaction [quinocetone results in increased expression of NFE2L2 mRNA]; Curcumin promotes the reaction [sodium arsenite results in increased expression of NFE2L2 protein]; Curcumin results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of GCLC mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of GCLM mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of HMOX1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of NQO1 protein]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of GCLC mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of GCLM mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of HMOX1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of NQO1 protein]; NFE2L2 protein affects the reaction [[Curcumin co-treated with sodium arsenite] promotes the reaction TFEB protein]; NFE2L2 protein affects the reaction [Curcumin analog results in decreased susceptibility to Acrolein]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in decreased expression of BCL2 protein]]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in decreased expression of SOD2 protein]]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in increased expression of HMOX1 protein]]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in increased expression of LAMP1 protein]]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in increased expression of SQSTM1 protein]]; NFE2L2 protein affects the reaction [Curcumin results in decreased susceptibility to Acrolein]
Curcumin results in increased expression of NFE2L2 mRNA; Curcumin results in increased expression of NFE2L2 protein
Curcumin analog results in increased expression of NFE2L2 protein; Curcumin results in increased expression of NFE2L2 mRNA; Curcumin results in increased expression of NFE2L2 protein; Curcumin results in increased expression of NFE2L2 protein modified form
Curcumin results in increased activity of NFE2L2 protein
NFE2L2 gene mutant form results in decreased susceptibility to Curcumin
Curcumin analog results in decreased methylation of NFE2L2 promoter
Curcumin affects the localization of NFE2L2 protein; Curcumin analog affects the localization of NFE2L2 protein
Curcumin results in increased localization of NFE2L2 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin affects the localization of NFE2L2 protein]; [Curcumin analog co-treated with APP protein modified form] results in increased expression of NFE2L2 protein; [Curcumin co-treated with APP protein modified form] results in increased expression of NFE2L2 protein; [Sitagliptin Phosphate co-treated with Curcumin] inhibits the reaction [decamethrin results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [Acetaminophen results in decreased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [Acetaminophen results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [decamethrin results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NFE2L2 protein modified form]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [maleic acid affects the expression of NFE2L2 protein]; Curcumin inhibits the reaction [Paraquat results in increased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [Paraquat results in increased expression of NFE2L2 protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [Streptozocin affects the localization of NFE2L2 protein]; Curcumin inhibits the reaction [Thioacetamide results in decreased expression of NFE2L2 mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NFE2L2 mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NFE2L2 protein]; Curcumin promotes the reaction [Diethylhexyl Phthalate results in increased expression of NFE2L2 mRNA]; Curcumin promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]; Curcumin results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 protein promotes the reaction [Curcumin results in increased activity of RELA protein]; NFE2L2 protein promotes the reaction [Curcumin results in increased expression of AKR1B1 mRNA]; NFE2L2 protein promotes the reaction [Curcumin results in increased expression of AKR1B1 protein]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in decreased expression of NFE2L2 mRNA]]; pyrazolanthrone inhibits the reaction [Curcumin affects the localization of NFE2L2 protein]; SB 203580 inhibits the reaction [Curcumin affects the localization of NFE2L2 protein]
Curcumin analog results in increased expression of NFE2L2 mRNA; Curcumin analog results in increased expression of NFE2L2 protein; Curcumin results in increased expression of NFE2L2 mRNA; Curcumin results in increased expression of NFE2L2 protein
[Curcumin co-treated with Acetaminophen] results in increased expression of NFE2L2 mRNA; [Curcumin co-treated with Acetaminophen] results in increased expression of NFE2L2 protein; [Curcumin co-treated with Benzo(a)pyrene] affects the localization of NFE2L2 protein; Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of NFE2L2 protein]; Curcumin promotes the reaction [sodium arsenite results in increased expression of NFE2L2 mRNA]; Curcumin promotes the reaction [sodium arsenite results in increased expression of NFE2L2 protein]; NFE2L2 gene mutant form affects the reaction [Curcumin promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 protein]]; NFE2L2 gene mutant form inhibits the reaction [Curcumin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]]; NFE2L2 gene mutant form inhibits the reaction [Curcumin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]]; NFE2L2 gene mutant form inhibits the reaction [Curcumin promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 mRNA]]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in decreased expression of CASP3 protein modified form]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in decreased expression of IL1B mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in decreased expression of IL6 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in decreased expression of TNF mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of BCL2 protein]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of GCLC mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of HMOX1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of NQO1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of NQO1 protein]; NFE2L2 protein affects the reaction [Curcumin results in increased expression of HMOX1 mRNA]		 CTD PMID:17449203 PMID:17535857 PMID:17640564 PMID:18006204 PMID:18321868 More... NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions
decreases activity
decreases expression
decreases localization		 ISO
EXP		 Curcumin inhibits the reaction [Lipopolysaccharides promotes the reaction [NFKB1 protein binds to IL18 promoter]]; Curcumin inhibits the reaction [Oxygen deficiency affects the localization of NFKB1 protein]; Curcumin inhibits the reaction [Paclitaxel results in increased activity of NFKB1 protein]; Curcumin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Curcumin inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]; Curcumin results in decreased activity of [NFKB1 protein binds to RELA protein]; Dithiothreitol inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]]
Curcumin analog results in decreased activity of NFKB1 protein; Curcumin results in decreased activity of NFKB1 protein
[Zinc binds to Curcumin] which affects the expression of NFKB1 mRNA; Curcumin inhibits the reaction [Ethanol promotes the reaction [Lipopolysaccharides results in increased activity of [RELA protein binds to NFKB1 protein]]]
Curcumin inhibits the reaction [[NFKB1 protein binds to RELA protein] which results in increased expression of ABCB1B mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; Curcumin inhibits the reaction [NFKB1 protein binds to RELA protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of NFKB1 mRNA]
Curcumin results in decreased expression of NFKB1 protein
Curcumin results in decreased localization of NFKB1 protein		 CTD PMID:15489888 PMID:16023083 PMID:16173963 PMID:16219905 PMID:16243823 More... NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 decreases activity ISO Curcumin results in decreased activity of NFKB2 protein CTD PMID:16173963 NCBI chr19:46,285,478...46,300,839
Ensembl chr19:46,292,759...46,300,824 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions
decreases phosphorylation
increases expression
decreases expression		 ISO
EXP		 Curcumin inhibits the reaction [Acetylmuramyl-Alanyl-Isoglutamine results in increased phosphorylation of NFKBIA protein]; Curcumin inhibits the reaction [bisphenol A results in increased expression of NFKBIA protein modified form]; Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NFKBIA mRNA]; Curcumin inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [IL1B protein results in increased phosphorylation of NFKBIA protein]; Curcumin inhibits the reaction [NFKBIA protein results in increased degradation of RELA protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of NFKBIA mRNA]; Curcumin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of NFKBIA protein]; Curcumin inhibits the reaction [Paclitaxel results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [Sodium Fluoride results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; NFKBIA protein affects the reaction [Curcumin results in decreased expression of CXCL1 mRNA]; NFKBIA protein affects the reaction [Curcumin results in decreased expression of CXCL2 mRNA]; NFKBIA protein inhibits the reaction [Curcumin results in decreased expression of CCN2 mRNA]
Curcumin inhibits the reaction [Fluorouracil results in decreased expression of NFKBIA protein]; Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of NFKBIA protein]
Curcumin results in decreased phosphorylation of NFKBIA protein
Curcumin results in increased expression of NFKBIA protein
CD40 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]; Curcumin analog inhibits the reaction [Copper Sulfate results in increased expression of NFKBIA mRNA]; Curcumin inhibits the reaction [Copper Sulfate results in increased expression of NFKBIA mRNA]; Curcumin inhibits the reaction [Fructose results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased degradation of NFKBIA protein]; ICAM1 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]
Curcumin results in decreased expression of NFKBIA protein		 CTD PMID:12216086 PMID:15489888 PMID:15793857 PMID:16023083 PMID:16219905 More... NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Nfkbib nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta multiple interactions ISO Curcumin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIB protein] CTD PMID:16934299 NCBI chr 7:28,457,676...28,466,069
Ensembl chr 7:28,457,676...28,466,937 		JBrowse link
G Nfya nuclear transcription factor-Y alpha decreases expression ISO Curcumin results in decreased expression of NFYA mRNA CTD PMID:15713895 NCBI chr17:48,693,917...48,716,782
Ensembl chr17:48,693,913...48,716,934 		JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) decreases expression ISO Curcumin results in decreased expression of NGFR mRNA CTD PMID:33539684 NCBI chr11:95,459,644...95,478,524
Ensembl chr11:95,459,644...95,478,561 		JBrowse link
G Nhlrc2 NHL repeat containing 2 decreases expression ISO Curcumin results in decreased expression of NHLRC2 mRNA CTD PMID:17999991 NCBI chr19:56,536,682...56,591,935
Ensembl chr19:56,536,693...56,591,935 		JBrowse link
G Nkx2-5 NK2 homeobox 5 decreases expression EXP Curcumin results in decreased expression of NKX2-5 mRNA CTD PMID:27237783 NCBI chr17:27,057,638...27,063,962
Ensembl chr17:27,057,638...27,063,983 		JBrowse link
G Nkx3-1 NK3 homeobox 1 decreases expression ISO Curcumin results in decreased expression of NKX3-1 mRNA; Curcumin results in decreased expression of NKX3-1 protein CTD PMID:17303007 PMID:18719366 NCBI chr14:69,428,141...69,432,107
Ensembl chr14:69,428,087...69,432,111 		JBrowse link
G Nlrp12 NLR family, pyrin domain containing 12 multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of NLRP12 mRNA] CTD PMID:23452621 NCBI chr 7:3,267,317...3,298,400
Ensembl chr 7:3,267,458...3,298,370 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NLRP3 mRNA]; [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NLRP3 protein]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NLRP3 mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of NLRP3 mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of NLRP3 protein] CTD PMID:34998855 PMID:35063475 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782 		JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 increases expression ISO Curcumin results in increased expression of NME1 mRNA CTD PMID:17198877 NCBI chr11:93,849,751...93,859,341
Ensembl chr11:93,847,805...93,859,347 		JBrowse link
G Nmt2 N-myristoyltransferase 2 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of NMT2 mRNA] CTD PMID:18200517 NCBI chr 2:3,285,249...3,329,914
Ensembl chr 2:3,285,249...3,329,914 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of NOD1 mRNA] CTD PMID:23452621 NCBI chr 6:54,900,927...54,949,655
Ensembl chr 6:54,900,934...54,949,597 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 multiple interactions ISO Curcumin inhibits the reaction [Acetylmuramyl-Alanyl-Isoglutamine promotes the reaction [NOD2 protein binds to NOD2 protein]]; Curcumin inhibits the reaction [lauric acid promotes the reaction [NOD2 protein binds to NOD2 protein]] CTD PMID:18413660 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Nos1 nitric oxide synthase 1, neuronal multiple interactions ISO
EXP		 Curcumin promotes the reaction [Sildenafil Citrate results in increased expression of NOS1 mRNA]
Curcumin inhibits the reaction [Cadmium Chloride results in decreased expression of NOS1 protein]		 CTD PMID:17627722 PMID:24662163 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions
decreases activity
affects expression
affects activity		 ISO
EXP		 Curcumin inhibits the reaction [Paraquat results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [quinocetone results in increased activity of NOS2 protein]; Curcumin inhibits the reaction [quinocetone results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of NOS2 protein]]
Curcumin results in decreased activity of NOS2 protein
[Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of NOS2 mRNA]; Curcumin analog inhibits the reaction [Rotenone results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Acetaminophen results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Dinitrochlorobenzene results in decreased expression of NOS2 protein]; Curcumin inhibits the reaction [Doxorubicin results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Kainic Acid results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Sodium Selenite results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Sodium Selenite results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of NOS2 protein]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in increased expression of NOS2 protein]]
Curcumin inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Chloranil results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased activity of NOS2 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [lipoteichoic acid results in increased expression of NOS2 protein]; NFE2L2 gene mutant form inhibits the reaction [Curcumin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]]
Curcumin affects the expression of NOS2 mRNA
Curcumin affects the activity of NOS2 protein		 CTD PMID:7530002 PMID:12628514 PMID:16934299 PMID:17373747 PMID:17434272 More... NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell multiple interactions ISO Curcumin inhibits the reaction [CXCL12 protein results in increased phosphorylation of NOS3 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of NOS3 protein modified form]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of NOS3 protein] CTD PMID:18660423 PMID:23452621 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Notch1 notch 1 decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of NOTCH1 mRNA; Curcumin results in decreased expression of NOTCH1 protein
[Curcumin co-treated with Isoflavones] results in decreased expression of NOTCH1 protein		 CTD PMID:17927689 PMID:18640131 NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675 		JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions ISO Curcumin inhibits the reaction [Cyclosporine results in increased expression of NOX4 protein] CTD PMID:32569592 NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918 		JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 multiple interactions EXP Curcumin inhibits the reaction [bisphenol A results in increased expression of NPC1L1 protein] CTD PMID:37701206 NCBI chr11:6,161,011...6,180,245
Ensembl chr11:6,161,013...6,180,143 		JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 decreases expression ISO Curcumin results in decreased expression of NPC2 mRNA CTD PMID:17198877 NCBI chr12:84,801,333...84,819,886
Ensembl chr12:84,801,336...84,819,926 		JBrowse link
G Nppa natriuretic peptide type A multiple interactions
decreases expression		 ISO carboxymethyl-chitosan analog promotes the reaction [Curcumin results in decreased expression of NPPA mRNA] CTD PMID:26612707 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression
increases activity
multiple interactions		 ISO
EXP		 Curcumin results in increased expression of NQO1 mRNA; Curcumin results in increased expression of NQO1 protein
Curcumin results in increased activity of NQO1 protein
Curcumin analog results in increased expression of NQO1 mRNA; Curcumin analog results in increased expression of NQO1 protein; Curcumin results in increased expression of NQO1 mRNA; Curcumin results in increased expression of NQO1 protein
Curcumin analog inhibits the reaction [Rotenone results in decreased expression of NQO1 mRNA]; Curcumin inhibits the reaction [Acetaminophen results in decreased expression of NQO1 mRNA]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of NQO1 mRNA]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of NQO1 protein]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NQO1 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NQO1 protein]; Curcumin inhibits the reaction [Paraquat results in increased activity of NQO1 protein]
[Curcumin co-treated with Chloranil] results in increased expression of NQO1 protein; Curcumin affects the expression of and results in increased activity of NQO1 protein; Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of NQO1 mRNA]; Curcumin promotes the reaction [sodium arsenite results in increased expression of NQO1 protein]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of NQO1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in increased expression of NQO1 protein]
Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of NQO1 protein]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of NQO1 mRNA]; NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of NQO1 protein]		 CTD PMID:12628514 PMID:17198877 PMID:17535857 PMID:18299980 PMID:18321868 More... NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 increases expression
multiple interactions		 ISO
EXP		 Curcumin results in increased expression of NR1H3 mRNA
Curcumin inhibits the reaction [bisphenol A results in increased expression of NR1H3 mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased expression of NR1H3 protein]
[Curcumin cotreated with oxidized LDL] increases expression of Nr1h3 protein in macrophages		 CTD
RGD		 PMID:16713233 PMID:37701206 PMID:25064633 RGD:401850557 NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
affects expression		 ISO Curcumin results in increased activity of NR1I2 protein
Curcumin affects the expression of NR1I2 mRNA		 CTD PMID:17210444 PMID:29933105 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases expression
multiple interactions		 ISO Curcumin results in increased expression of NR3C1 mRNA
Curcumin inhibits the reaction [Dexamethasone results in increased phosphorylation of NR3C1 protein]		 CTD PMID:17022948 PMID:18483179 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression ISO Curcumin results in decreased expression of NR4A2 mRNA CTD PMID:17999991 NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 multiple interactions
decreases expression		 ISO NRIP1 mRNA alternative form inhibits the reaction [Curcumin results in increased expression of MIR532 mRNA]
Curcumin results in decreased expression of NRIP1 mRNA alternative form		 CTD PMID:37471645 NCBI chr16:76,084,291...76,170,930
Ensembl chr16:76,084,288...76,170,715 		JBrowse link
G Ntn1 netrin 1 multiple interactions ISO Curcumin inhibits the reaction [Cadmium Chloride results in increased export of NTN1 protein] CTD PMID:29421648 NCBI chr11:68,100,190...68,277,652
Ensembl chr11:68,100,190...68,291,649 		JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 multiple interactions ISO Curcumin inhibits the reaction [sodium arsenite results in decreased expression of NTRK2 protein] CTD PMID:29723552 NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784 		JBrowse link
G Nup98 nucleoporin 98 increases expression ISO Curcumin results in increased expression of NUP98 mRNA CTD PMID:17198877 NCBI chr 7:101,768,607...101,859,359
Ensembl chr 7:101,768,605...101,859,383 		JBrowse link
G Oat ornithine aminotransferase affects expression ISO Curcumin affects the expression of OAT mRNA CTD PMID:18539377 NCBI chr 7:132,159,204...132,178,127
Ensembl chr 7:132,159,207...132,178,127 		JBrowse link
G Ocln occludin multiple interactions EXP Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein] CTD PMID:35817260 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226 		JBrowse link
G Odc1 ornithine decarboxylase, structural 1 increases expression
multiple interactions		 ISO
EXP		 Curcumin results in increased expression of ODC1 mRNA
Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]		 CTD PMID:12628514 PMID:17198877 NCBI chr12:17,594,906...17,601,503
Ensembl chr12:17,594,795...17,601,506 		JBrowse link
G Ogg1 8-oxoguanine DNA-glycosylase 1 multiple interactions ISO Curcumin inhibits the reaction [Arsenic results in increased expression of OGG1 mRNA]; Curcumin inhibits the reaction [Arsenic results in increased expression of OGG1 protein] CTD PMID:21332098 NCBI chr 6:113,303,959...113,311,149
Ensembl chr 6:113,303,933...113,312,029 		JBrowse link
G Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 multiple interactions ISO Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OLR1 mRNA] CTD PMID:23386263 NCBI chr 6:129,456,113...129,484,312
Ensembl chr 6:129,462,207...129,484,128 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions ISO Curcumin inhibits the reaction [Cisplatin results in decreased expression of OPA1 protein] CTD PMID:28698153 NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702 		JBrowse link
G Osmr oncostatin M receptor multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of OSMR mRNA] CTD PMID:18200517 NCBI chr15:6,843,049...6,904,434
Ensembl chr15:6,843,058...6,904,450 		JBrowse link
G Otud7b OTU domain containing 7B decreases expression ISO Curcumin results in decreased expression of OTUD7B mRNA CTD PMID:18421014 NCBI chr 3:96,011,759...96,068,446
Ensembl chr 3:96,011,839...96,068,446 		JBrowse link
G Pah phenylalanine hydroxylase decreases expression EXP Curcumin results in decreased expression of PAH mRNA CTD PMID:19555370 NCBI chr10:87,357,657...87,419,999
Ensembl chr10:87,357,657...87,419,998 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 decreases cleavage ISO Curcumin results in decreased cleavage of PAK2 protein CTD PMID:15095415 NCBI chr16:31,835,108...31,898,160
Ensembl chr16:31,835,108...31,898,160 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
increases expression
decreases cleavage
decreases expression
increases cleavage
increases degradation		 ISO
EXP		 [Curcumin co-treated with Bortezomib] results in increased cleavage of PARP1 protein; [Curcumin co-treated with Thalidomide] results in increased cleavage of PARP1 protein; arsenic trioxide promotes the reaction [Curcumin results in increased expression of PARP1 protein modified form]; Curcumin inhibits the reaction [Arsenic results in decreased expression of PARP1 mRNA]; Curcumin inhibits the reaction [Arsenic results in decreased expression of PARP1 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of PARP1 protein]; Curcumin inhibits the reaction [docetaxel results in increased cleavage of PARP1 protein]; Curcumin inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]; Curcumin promotes the reaction [arsenic trioxide results in increased expression of PARP1 protein modified form]; Curcumin promotes the reaction [arsenite results in increased expression of PARP1 protein]; Curcumin results in increased cleavage of and results in increased activity of PARP1 protein
Curcumin results in decreased cleavage of PARP1 protein
Curcumin analog results in decreased expression of PARP1 mRNA
Curcumin results in increased cleavage of PARP1 protein
carboxymethyl-chitosan analog promotes the reaction [Curcumin results in decreased cleavage of PARP1 protein]; Curcumin inhibits the reaction [AGT protein modified form results in increased cleavage of PARP1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of PARP1 protein]; Curcumin inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]
[Doxorubicin co-treated with Curcumin] results in increased cleavage of PARP1 protein; Curcumin inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]
Curcumin results in increased degradation of PARP1		 CTD PMID:11035063 PMID:14555224 PMID:14724571 PMID:15569404 PMID:16023083 More... NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Pax6 paired box 6 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [bisphenol A results in decreased expression of PAX6 mRNA]
Curcumin results in increased expression of PAX6 mRNA		 CTD PMID:25963729 NCBI chr 2:105,499,241...105,528,755
Ensembl chr 2:105,499,245...105,527,709 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic decreases expression
affects expression		 ISO
EXP		 Curcumin results in decreased expression of PCK1 mRNA
Curcumin affects the expression of PCK1 mRNA		 CTD PMID:17198877 PMID:27208389 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression
multiple interactions
increases expression		 ISO Curcumin results in decreased expression of PCNA protein
[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in increased expression of PCNA protein]; [Curcumin binds to carboxymethyl-chitosan analog] which results in decreased expression of PCNA protein
[Dihydrotestosterone co-treated with Curcumin co-treated with Quercetin] results in increased expression of PCNA protein; Curcumin inhibits the reaction [bisphenol A results in increased expression of PCNA protein]
Curcumin results in increased expression of PCNA mRNA		 CTD PMID:16101141 PMID:18226269 PMID:23222814 PMID:24831732 PMID:26612707 More... NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 affects expression EXP Curcumin affects the expression of PCSK9 mRNA CTD PMID:27208389 NCBI chr 4:106,299,531...106,321,522
Ensembl chr 4:106,299,526...106,321,526 		JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide multiple interactions ISO Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFB protein]; Curcumin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]; tin protoporphyrin IX inhibits the reaction [Curcumin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]]; tin protoporphyrin IX inhibits the reaction [Curcumin inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]] CTD PMID:18006644 PMID:18784349 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178 		JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide increases expression
decreases phosphorylation
multiple interactions
decreases expression		 ISO Curcumin results in increased expression of PDGFRB mRNA
Curcumin results in decreased phosphorylation of PDGFRB protein
Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of PDGFRB mRNA]
Curcumin results in decreased expression of PDGFRB mRNA; Curcumin results in decreased expression of PDGFRB protein		 CTD PMID:17372590 PMID:18006644 PMID:18332871 PMID:21594647 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133 		JBrowse link
G Pdia3 protein disulfide isomerase associated 3 increases expression ISO Curcumin results in increased expression of PDIA3 mRNA CTD PMID:29723631 NCBI chr 2:121,244,383...121,269,168
Ensembl chr 2:121,244,256...121,269,168 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 multiple interactions
increases phosphorylation		 ISO Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of PDK1 protein]; Buthionine Sulfoximine promotes the reaction [Curcumin results in increased phosphorylation of PDK1 protein]; Glutathione inhibits the reaction [Curcumin results in increased phosphorylation of PDK1 protein] CTD PMID:17171638 NCBI chr 2:71,703,398...71,734,202
Ensembl chr 2:71,703,568...71,734,202 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 decreases phosphorylation ISO Curcumin results in decreased phosphorylation of PDPK1 protein CTD PMID:34634291 NCBI chr17:24,292,654...24,370,957
Ensembl chr17:24,292,654...24,369,898 		JBrowse link
G Pdpn podoplanin multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PDPN mRNA] CTD PMID:18200517 NCBI chr 4:142,993,979...143,026,134
Ensembl chr 4:142,994,001...143,026,134 		JBrowse link
G Pecam1 platelet/endothelial cell adhesion molecule 1 affects expression
multiple interactions
increases expression
decreases expression		 ISO
EXP		 Curcumin affects the expression of PECAM1 protein
Curcumin inhibits the reaction [Particulate Matter results in increased expression of PECAM1 protein]; Curcumin inhibits the reaction [titanium dioxide results in increased expression of PECAM1 protein]
Curcumin results in increased expression of PECAM1 protein
Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of PECAM1 mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of PECAM1 protein]
Gemcitabine promotes the reaction [Curcumin results in decreased expression of PECAM1 protein]		 CTD PMID:17440100 PMID:17960570 PMID:23845850 PMID:29244817 NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454 		JBrowse link
G Per2 period circadian clock 2 increases expression ISO Curcumin results in increased expression of PER2 mRNA CTD PMID:17198877 NCBI chr 1:91,343,699...91,387,028
Ensembl chr 1:91,343,704...91,387,046 		JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 decreases expression ISO Curcumin results in decreased expression of PFKFB4 mRNA CTD PMID:17198877 NCBI chr 9:108,817,336...108,861,302
Ensembl chr 9:108,820,846...108,861,296 		JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO Curcumin results in increased expression of PGD mRNA CTD PMID:18299980 NCBI chr 4:149,234,448...149,251,162
Ensembl chr 4:149,234,448...149,251,228 		JBrowse link
G Pgf placental growth factor multiple interactions ISO Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of PGF mRNA] CTD PMID:23845850 NCBI chr12:85,213,413...85,224,087
Ensembl chr12:85,213,409...85,224,564 		JBrowse link
G Pgs1 phosphatidylglycerophosphate synthase 1 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PGS1 mRNA] CTD PMID:18200517 NCBI chr11:117,876,505...117,914,837
Ensembl chr11:117,877,118...117,914,837 		JBrowse link
G Phb1 prohibitin 1 decreases expression ISO Curcumin results in decreased expression of PHB1 protein CTD PMID:19137819 NCBI chr11:95,557,783...95,571,599
Ensembl chr11:95,557,783...95,571,599 		JBrowse link
G Phyh phytanoyl-CoA hydroxylase decreases expression ISO Curcumin results in decreased expression of PHYH mRNA CTD PMID:18539377 NCBI chr 2:4,923,807...4,943,554
Ensembl chr 2:4,923,830...4,943,541 		JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha decreases expression ISO Curcumin analog results in decreased expression of PIK3C2A mRNA CTD PMID:26409325 NCBI chr 7:115,936,500...116,042,693
Ensembl chr 7:115,936,500...116,042,684 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha decreases expression ISO Curcumin analog results in decreased expression of PIK3CA mRNA CTD PMID:26409325 NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635 		JBrowse link
G Pink1 PTEN induced putative kinase 1 multiple interactions ISO Curcumin inhibits the reaction [Cisplatin results in increased expression of PINK1 protein] CTD PMID:28698153 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618 		JBrowse link
G Pir pirin increases expression ISO Curcumin results in increased expression of PIR mRNA CTD PMID:18299980 NCBI chr  X:163,052,427...163,156,009
Ensembl chr  X:163,052,367...163,156,007 		JBrowse link
G Pirb paired Ig-like receptor B multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LILRB3 mRNA] CTD PMID:18200517 NCBI chr 7:3,715,504...3,723,381
Ensembl chr 7:3,714,408...3,723,390 		JBrowse link
G Pkm pyruvate kinase, muscle multiple interactions ISO ATF4 inhibits the reaction [Curcumin results in decreased expression of PKM protein]; Curcumin inhibits the reaction [4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine results in increased phosphorylation of PKM protein]; Curcumin inhibits the reaction [Sirolimus results in increased expression of PKM protein] CTD PMID:36640941 NCBI chr 9:59,563,859...59,586,655
Ensembl chr 9:59,563,651...59,586,658 		JBrowse link
G Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PLA2G2A mRNA] CTD PMID:18200517 NCBI chr 4:138,559,168...138,562,500
Ensembl chr 4:138,559,171...138,562,497 		JBrowse link
G Plau plasminogen activator, urokinase decreases secretion
multiple interactions
increases expression
decreases expression		 ISO
EXP		 Curcumin results in decreased secretion of PLAU protein
Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAU mRNA]; Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAU protein]
Curcumin results in increased expression of PLAU mRNA
TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of PLAU protein]		 CTD PMID:18025290 PMID:18226269 PMID:18495463 PMID:35716765 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression
multiple interactions		 ISO
EXP		 Curcumin results in increased expression of PLAUR mRNA
Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAUR mRNA]; Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAUR protein]		 CTD PMID:15713895 PMID:35716765 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393 		JBrowse link
G Plcg1 phospholipase C, gamma 1 multiple interactions ISO curcumin inhibits the reaction [azoxymethane increases activity of Plcg1 protein in colonic mucosa] RGD PMID:7812955 RGD:151356942 NCBI chr 2:160,573,230...160,617,680
Ensembl chr 2:160,573,220...160,617,680 		JBrowse link
G Plekhh2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 increases expression ISO Curcumin results in increased expression of PLEKHH2 mRNA CTD PMID:18421014 NCBI chr17:84,819,303...84,929,571
Ensembl chr17:84,819,323...84,929,566 		JBrowse link
G Plk1 polo like kinase 1 decreases expression ISO Curcumin analog results in decreased expression of PLK1 mRNA CTD PMID:26409325 NCBI chr 7:121,758,658...121,769,107
Ensembl chr 7:121,758,662...121,769,096 		JBrowse link
G Plk2 polo like kinase 2 increases expression ISO Curcumin analog results in increased expression of PLK2 mRNA CTD PMID:26409325 NCBI chr13:110,531,578...110,537,378
Ensembl chr13:110,531,580...110,537,378 		JBrowse link
G Plk3 polo like kinase 3 increases expression ISO Curcumin analog results in increased expression of PLK3 mRNA CTD PMID:26409325 NCBI chr 4:116,985,852...116,991,244
Ensembl chr 4:116,985,852...116,991,160 		JBrowse link
G Plk4 polo like kinase 4 increases expression ISO Curcumin analog results in increased expression of PLK4 mRNA CTD PMID:26409325 NCBI chr 3:40,754,463...40,771,318
Ensembl chr 3:40,754,454...40,771,318 		JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PLOD2 mRNA] CTD PMID:18200517 NCBI chr 9:92,421,828...92,490,481
Ensembl chr 9:92,424,276...92,490,481 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Curcumin results in increased expression of PMAIP1 mRNA CTD PMID:17332930 NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636 		JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 decreases expression ISO Curcumin results in decreased expression of PMEPA1 mRNA CTD PMID:18719366 NCBI chr 2:173,066,251...173,118,329
Ensembl chr 2:173,066,251...173,118,326 		JBrowse link
G Pola2 polymerase (DNA directed), alpha 2 decreases expression ISO Curcumin results in decreased expression of POLA2 mRNA CTD PMID:18299980 NCBI chr19:5,990,574...6,014,266
Ensembl chr19:5,990,570...6,014,230 		JBrowse link
G Polb polymerase (DNA directed), beta multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Arsenic results in decreased expression of POLB mRNA]; Curcumin inhibits the reaction [Arsenic results in decreased expression of POLB protein]
Curcumin results in decreased expression of POLB protein		 CTD PMID:19401701 PMID:21332098 NCBI chr 8:23,118,135...23,143,482
Ensembl chr 8:23,118,142...23,143,451 		JBrowse link
G Pole polymerase (DNA directed), epsilon decreases expression ISO Curcumin results in decreased expression of POLE mRNA CTD PMID:18299980 NCBI chr 5:110,434,185...110,485,319
Ensembl chr 5:110,434,172...110,485,340 		JBrowse link
G Porcn porcupine O-acyltransferase multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [bisphenol A results in decreased expression of PORCN mRNA]
Curcumin results in increased expression of PORCN mRNA		 CTD PMID:25963729 NCBI chr  X:8,060,085...8,072,794
Ensembl chr  X:8,060,087...8,072,764 		JBrowse link
G Postn periostin, osteoblast specific factor increases expression ISO Curcumin results in increased expression of POSTN mRNA CTD PMID:21594647 NCBI chr 3:54,266,688...54,298,462
Ensembl chr 3:54,268,530...54,298,458 		JBrowse link
G Pou5f1 POU domain, class 5, transcription factor 1 multiple interactions
decreases expression
increases expression		 EXP
ISO		 2-methoxyestradiol inhibits the reaction [Curcumin results in increased expression of POU5F1 mRNA]
Curcumin results in decreased expression of POU5F1 mRNA; Curcumin results in decreased expression of POU5F1 protein
WWTR1 protein inhibits the reaction [Curcumin results in decreased expression of POU5F1 mRNA]; WWTR1 protein inhibits the reaction [Curcumin results in decreased expression of POU5F1 protein]
Curcumin results in increased expression of POU5F1 mRNA; Curcumin results in increased expression of POU5F1 protein		 CTD PMID:25822711 PMID:27237783 PMID:33539684 NCBI chr17:35,816,929...35,821,674
Ensembl chr17:35,816,915...35,821,669 		JBrowse link
G Ppard peroxisome proliferator activator receptor delta decreases expression ISO Curcumin results in decreased expression of PPARD mRNA; Curcumin results in decreased expression of PPARD protein CTD PMID:19294764 NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma affects binding
decreases expression
increases expression
increases activity
affects localization
multiple interactions		 ISO
EXP		 Curcumin binds to PPARG protein
Curcumin results in decreased expression of PPARG mRNA
Curcumin results in increased expression of PPARG mRNA; Curcumin results in increased expression of PPARG protein
Curcumin results in increased activity of PPARG protein
Curcumin results in decreased expression of PPARG protein
Curcumin affects the localization of PPARG protein
Curcumin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of PPARG mRNA]]; Curcumin inhibits the reaction [Dietary Fats results in increased expression of PPARG mRNA]; Curcumin results in decreased expression of and results in decreased activity of PPARG protein
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in decreased activity of PPARG protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in increased expression of PPARG mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in increased expression of PPARG protein]; Buthionine Sulfoximine inhibits the reaction [Curcumin results in increased expression of PPARG mRNA]; Buthionine Sulfoximine inhibits the reaction [Curcumin results in increased expression of PPARG protein]; Curcumin inhibits the reaction [[SMAD4 protein binds to SMAD3 protein] which binds to PPARG promoter]; Curcumin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPARG mRNA]; Curcumin inhibits the reaction [EGF protein results in decreased expression of PPARG mRNA]; Curcumin inhibits the reaction [EGF protein results in decreased expression of PPARG protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in decreased activity of PPARG protein]; Curcumin inhibits the reaction [TGFB1 protein results in decreased expression of PPARG mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of PPARG protein]
PPARG protein promotes the reaction [Curcumin results in decreased expression of CCN2 mRNA]
Curcumin results in decreased expression of PPARG protein modified form		 CTD PMID:15486348 PMID:15713005 PMID:16782535 PMID:16959952 PMID:17372590 More... NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with Tobacco Smoke Pollution] results in decreased expression of PPARGC1A mRNA]; Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with Tobacco Smoke Pollution] results in decreased expression of PPARGC1A protein]; Curcumin inhibits the reaction [Potassium Dichromate results in decreased expression of PPARGC1A protein]
Curcumin results in increased expression of PPARGC1A protein		 CTD PMID:28951138 PMID:32980475 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Ppdpf pancreatic progenitor cell differentiation and proliferation factor increases expression ISO Curcumin results in increased expression of PPDPF mRNA CTD PMID:17198877 NCBI chr 2:180,828,615...180,830,297
Ensembl chr 2:180,829,040...180,830,564 		JBrowse link
G Ppif peptidylprolyl isomerase F (cyclophilin F) increases expression ISO Curcumin results in increased expression of PPIF mRNA CTD PMID:17198877 NCBI chr14:25,693,998...25,700,892
Ensembl chr14:25,694,578...25,700,892 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha multiple interactions ISO Curcumin inhibits the reaction [sodium arsenite results in increased phosphorylation of PPP1CA protein] CTD PMID:27966075 NCBI chr19:4,242,173...4,245,418
Ensembl chr19:4,242,064...4,245,419 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory inhibitor subunit 1B multiple interactions ISO Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of PPP1R1B protein] CTD PMID:27966075 NCBI chr11:98,239,232...98,248,622
Ensembl chr11:98,239,230...98,248,622 		JBrowse link
G Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform multiple interactions ISO Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of PPP2CA mRNA] CTD PMID:31521693 NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605 		JBrowse link
G Ppp3cc protein phosphatase 3, catalytic subunit, gamma isoform decreases expression ISO Curcumin results in decreased expression of PPP3CC mRNA CTD PMID:17198877 NCBI chr14:70,455,314...70,526,979
Ensembl chr14:70,455,314...70,526,920 		JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit multiple interactions ISO Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of PPP5C mRNA] CTD PMID:31521693 NCBI chr 7:16,738,575...16,761,812
Ensembl chr 7:16,738,565...16,761,849 		JBrowse link
G Prdx5 peroxiredoxin 5 multiple interactions ISO Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of PRDX5 protein] CTD PMID:36924976 NCBI chr19:6,884,065...6,887,474
Ensembl chr19:6,884,065...6,887,474 		JBrowse link
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit increases phosphorylation ISO Curcumin results in increased phosphorylation of PRKAA1 protein CTD PMID:18790744 NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380 		JBrowse link
G Prkca protein kinase C, alpha multiple interactions
decreases expression		 ISO [PRKCA protein results in increased phosphorylation of CFTR protein] promotes the reaction [Curcumin results in increased activity of CFTR protein]; PRKCA protein affects the reaction [Curcumin results in increased expression of HMOX1 protein]
Curcumin analog results in decreased expression of PRKCA mRNA		 CTD PMID:17178710 PMID:18357586 PMID:26409325 NCBI chr11:107,824,213...108,237,360
Ensembl chr11:107,824,213...108,234,754 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions
affects binding
increases phosphorylation		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased phosphorylation of PRKCD protein]; Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of PRKCD protein]; Buthionine Sulfoximine promotes the reaction [Curcumin results in increased phosphorylation of PRKCD protein]; Curcumin inhibits the reaction [PRKCD protein results in increased expression of IVL mRNA]; Glutathione inhibits the reaction [Curcumin results in increased phosphorylation of PRKCD protein]; PRKCD protein affects the reaction [Curcumin results in increased expression of HMOX1 protein]; PRKCD protein promotes the reaction [Curcumin results in increased expression of DDIT3 mRNA]; rottlerin inhibits the reaction [Curcumin results in increased phosphorylation of PRKCD protein]; Staurosporine inhibits the reaction [Curcumin results in increased phosphorylation of PRKCD protein]; Wortmannin inhibits the reaction [Curcumin results in increased phosphorylation of PRKCD protein]
Curcumin results in increased phosphorylation of and results in increased degradation of PRKCD protein
Curcumin binds to PRKCD protein		 CTD PMID:17148446 PMID:17171638 PMID:18357586 PMID:19161989 NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167 		JBrowse link
G Prkce protein kinase C, epsilon multiple interactions
decreases expression
decreases response to substance		 ISO Curcumin inhibits the reaction [PRKCE protein results in increased expression of IVL mRNA]
Curcumin analog results in decreased expression of PRKCE mRNA
PRKCE protein results in decreased susceptibility to Curcumin		 CTD PMID:14742295 PMID:17148446 PMID:26409325 NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347 		JBrowse link
G Prkch protein kinase C, eta multiple interactions ISO Curcumin inhibits the reaction [PRKCH protein results in increased expression of IVL mRNA] CTD PMID:17148446 NCBI chr12:73,631,570...73,824,959
Ensembl chr12:73,631,570...73,824,959 		JBrowse link
G Prkcq protein kinase C, theta multiple interactions ISO Curcumin inhibits the reaction [Fructose results in increased phosphorylation of PRKCQ protein] CTD PMID:26713546 NCBI chr 2:11,176,922...11,306,033
Ensembl chr 2:11,176,919...11,306,033 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Arsenic results in decreased expression of PRKDC mRNA]; Curcumin inhibits the reaction [Arsenic results in decreased expression of PRKDC protein]
Curcumin results in decreased expression of PRKDC mRNA		 CTD PMID:17596214 PMID:21332098 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions ISO Curcumin inhibits the reaction [Cisplatin results in increased expression of PRKN protein] CTD PMID:28698153 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Prlr prolactin receptor increases expression ISO Curcumin results in increased expression of PRLR mRNA CTD PMID:18421014 NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266 		JBrowse link
G Prom1 prominin 1 multiple interactions
decreases expression		 ISO WWTR1 protein inhibits the reaction [Curcumin results in decreased expression of PROM1 mRNA]; WWTR1 protein inhibits the reaction [Curcumin results in decreased expression of PROM1 protein]
Curcumin results in decreased expression of PROM1 mRNA; Curcumin results in decreased expression of PROM1 protein		 CTD PMID:33539684 NCBI chr 5:44,150,963...44,260,850
Ensembl chr 5:44,150,962...44,259,374 		JBrowse link
G Ptch1 patched 1 multiple interactions ISO [Arsenic Trioxide co-treated with Curcumin] inhibits the reaction [Cisplatin results in increased expression of PTCH1 mRNA]; Curcumin inhibits the reaction [Cisplatin results in increased expression of PTCH1 mRNA] CTD PMID:31612257 NCBI chr13:63,656,142...63,721,274
Ensembl chr13:63,656,142...63,721,412 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO Curcumin inhibits the reaction [bisphenol A results in increased expression of PTEN protein] CTD PMID:24831732 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Ptges prostaglandin E synthase multiple interactions ISO Curcumin inhibits the reaction [IL1B protein results in increased expression of PTGES protein] CTD PMID:27645308 NCBI chr 2:30,779,483...30,793,309
Ensembl chr 2:30,779,483...30,819,875 		JBrowse link
G Ptges2 prostaglandin E synthase 2 multiple interactions EXP Curcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of PTGES2 protein] CTD PMID:18321868 NCBI chr 2:32,285,902...32,292,752
Ensembl chr 2:32,285,908...32,295,784 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO Curcumin results in decreased expression of PTGS1 mRNA CTD PMID:20816778 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
increases expression
multiple interactions
affects expression		 ISO
EXP		 Curcumin analog results in decreased expression of PTGS2 mRNA; Curcumin results in decreased expression of PTGS2 mRNA; Curcumin results in decreased expression of PTGS2 protein
Curcumin analog results in increased expression of PTGS2 mRNA
[Curcumin co-treated with Gemcitabine] results in decreased expression of PTGS2 protein; Curcumin analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Chloranil results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [lipoteichoic acid results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]]
Curcumin results in increased expression of PTGS2 mRNA
[Curcumin co-treated with Azoxymethane] results in increased expression of PTGS2 mRNA; [Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Doxorubicin results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [Fructose results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Quartz results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [VIP protein results in increased expression of PTGS2 protein]
Curcumin affects the expression of PTGS2 mRNA
[Fluorouracil co-treated with Curcumin] results in decreased expression of PTGS2 protein; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [Nicotine results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [TNFSF11 protein results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [Tobacco Smoke Pollution results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [VEGFA protein results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [VEGFA protein results in increased expression of PTGS2 protein]; Curcumin promotes the reaction [Fluorouracil results in decreased phosphorylation of and results in decreased activity of PTGS2 protein]; Curcumin promotes the reaction [Folfox protocol results in decreased phosphorylation of and results in decreased activity of PTGS2 protein]; Curcumin results in decreased phosphorylation of and results in decreased activity of PTGS2 protein; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of PTGS2 protein]		 CTD PMID:15129424 PMID:15489888 PMID:15841493 PMID:15911101 PMID:16023083 More... NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Pthlh parathyroid hormone-like peptide multiple interactions ISO Curcumin inhibits the reaction [EGF protein results in increased secretion of PTHLH protein] CTD PMID:15129424 NCBI chr 6:147,153,607...147,165,511
Ensembl chr 6:147,153,599...147,165,681 		JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 decreases expression ISO Curcumin results in decreased expression of PTPN13 mRNA CTD PMID:15713895 NCBI chr 5:103,573,058...103,746,227
Ensembl chr 5:103,573,058...103,746,169 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 increases expression ISO Curcumin results in increased expression of PTPN6 mRNA CTD PMID:17198877 NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677 		JBrowse link
G Ptpn7 protein tyrosine phosphatase, non-receptor type 7 increases expression ISO Curcumin results in increased expression of PTPN7 mRNA CTD PMID:17198877 NCBI chr 1:135,059,577...135,073,064
Ensembl chr 1:135,060,438...135,073,055 		JBrowse link
G Ptpro protein tyrosine phosphatase receptor type O multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTPRO mRNA] CTD PMID:18200517 NCBI chr 6:137,229,189...137,440,251
Ensembl chr 6:137,229,317...137,440,231 		JBrowse link
G Ptprr protein tyrosine phosphatase receptor type R decreases expression ISO Curcumin results in decreased expression of PTPRR mRNA CTD PMID:21594647 NCBI chr10:115,854,093...116,110,837
Ensembl chr10:115,854,118...116,110,837 		JBrowse link
G Ptx3 pentraxin related gene multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTX3 mRNA] CTD PMID:18200517 NCBI chr 3:66,127,308...66,133,227
Ensembl chr 3:66,127,331...66,133,226 		JBrowse link
G Pycard PYD and CARD domain containing multiple interactions EXP Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of PYCARD mRNA] CTD PMID:35063475 NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039 		JBrowse link
G Rab8a RAB8A, member RAS oncogene family decreases expression ISO Curcumin results in decreased expression of RAB8A mRNA CTD PMID:21594647 NCBI chr 8:72,915,044...72,935,210
Ensembl chr 8:72,915,044...72,937,748 		JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO Curcumin inhibits the reaction [Doxorubicin results in increased expression of RAC1 mRNA] CTD PMID:34047412 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791 		JBrowse link
G Rad51 RAD51 recombinase multiple interactions ISO [Mitomycin co-treated with Curcumin] results in decreased expression of RAD51 mRNA; acetylleucyl-leucyl-norleucinal inhibits the reaction [[Mitomycin co-treated with Curcumin] results in decreased expression of RAD51 mRNA]; acetylleucyl-leucyl-norleucinal inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Mitomycin co-treated with Curcumin] results in decreased expression of RAD51 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]]; Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]; MAP2K1 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]]; MAP2K2 protein inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]]; RAD51 results in decreased susceptibility to [Curcumin co-treated with Mitomycin]; U 0126 promotes the reaction [[Mitomycin co-treated with Curcumin] results in decreased expression of RAD51 mRNA]; U 0126 promotes the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]] CTD PMID:21810436 NCBI chr 2:118,943,295...118,966,554
Ensembl chr 2:118,943,274...118,977,926 		JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 increases activity
multiple interactions		 EXP Curcumin results in increased activity of RAF1 protein
piperlongumine inhibits the reaction [Curcumin results in increased activity of RAF1 protein]		 CTD PMID:19501152 NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596 		JBrowse link
G Ramp1 receptor (calcitonin) activity modifying protein 1 decreases expression ISO Curcumin results in decreased expression of RAMP1 mRNA CTD PMID:17198877 NCBI chr 1:91,107,544...91,152,918
Ensembl chr 1:91,107,544...91,152,918 		JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions ISO Curcumin inhibits the reaction [TGFB1 protein results in increased expression of RARA mRNA] CTD PMID:8940178 NCBI chr11:98,818,626...98,865,768
Ensembl chr11:98,818,644...98,865,768 		JBrowse link
G Rassf2 Ras association (RalGDS/AF-6) domain family member 2 increases expression ISO Curcumin results in increased expression of RASSF2 mRNA CTD PMID:17198877 NCBI chr 2:131,834,770...131,872,336
Ensembl chr 2:131,831,335...131,872,178 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation
multiple interactions		 EXP
ISO		 Curcumin results in decreased phosphorylation of RB1 protein
Curcumin inhibits the reaction [bisphenol A results in increased phosphorylation of RB1 protein]		 CTD PMID:15738001 PMID:18156803 PMID:23222814 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262 		JBrowse link
G Rbm39 RNA binding motif protein 39 increases expression ISO Curcumin results in increased expression of RBM39 mRNA CTD PMID:17999991 NCBI chr 2:155,989,159...156,022,649
Ensembl chr 2:155,989,159...156,022,158 		JBrowse link
G Rbp1 retinol binding protein 1, cellular multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RBP1 mRNA] CTD PMID:18200517 NCBI chr 9:98,305,014...98,328,604
Ensembl chr 9:98,305,014...98,328,628 		JBrowse link
G Reg3b regenerating islet-derived 3 beta multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of REG3A mRNA] CTD PMID:18200517 NCBI chr 6:78,347,868...78,350,449
Ensembl chr 6:78,347,640...78,350,449 		JBrowse link
G Reg3d regenerating islet-derived 3 delta multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of REG3D mRNA] CTD PMID:18200517 NCBI chr 6:78,352,857...78,355,848
Ensembl chr 6:78,352,857...78,355,848 		JBrowse link
G Reg3g regenerating islet-derived 3 gamma multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of REG3G mRNA] CTD PMID:18200517 NCBI chr 6:78,443,252...78,445,857
Ensembl chr 6:78,443,252...78,445,855 		JBrowse link
G Rel reticuloendotheliosis oncogene multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Hydrogen Peroxide results in increased expression of REL mRNA]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of REL mRNA]; Curcumin promotes the reaction [Hydrogen Peroxide results in increased expression of REL protein]
Curcumin results in increased expression of REL protein		 CTD PMID:23452621 PMID:31521693 NCBI chr11:23,686,847...23,720,969
Ensembl chr11:23,686,847...23,720,970 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions
decreases expression
increases activity
affects activity
increases expression
decreases localization
decreases activity		 ISO
EXP		 [Curcumin co-treated with Isoflavones] results in decreased activity of RELA protein; Curcumin inhibits the reaction [Acetylmuramyl-Alanyl-Isoglutamine results in increased activity of RELA protein]; Curcumin inhibits the reaction [Acetylmuramyl-Alanyl-Isoglutamine results in increased phosphorylation of and affects the localization of RELA protein]; Curcumin inhibits the reaction [Acids results in increased activity of RELA protein]; Curcumin inhibits the reaction [Acrylamide results in increased expression of RELA protein]; Curcumin inhibits the reaction [bisphenol A results in increased expression of RELA protein modified form]; Curcumin inhibits the reaction [Doxorubicin results in increased expression of RELA]; Curcumin inhibits the reaction [Formaldehyde results in increased expression of RELA protein]; Curcumin inhibits the reaction [Glucose results in increased activity of RELA protein]; Curcumin inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Curcumin inhibits the reaction [IL1B protein results in increased phosphorylation of and results in increased activity of and results in increased localization of RELA protein]; Curcumin inhibits the reaction [lauric acid results in increased activity of RELA protein]; Curcumin inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to IL18 promoter]]; Curcumin inhibits the reaction [NFKBIA protein results in increased degradation of RELA protein]; Curcumin inhibits the reaction [Oxygen deficiency affects the localization of RELA protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of RELA mRNA]; Curcumin inhibits the reaction [Paclitaxel results in increased activity of RELA protein]; Curcumin inhibits the reaction [quinocetone results in increased expression of RELA mRNA]; Curcumin inhibits the reaction [RELA protein binds to MST1R promoter]; Curcumin inhibits the reaction [RELA protein results in increased expression of MST1R mRNA]; Curcumin inhibits the reaction [Sodium Fluoride results in increased phosphorylation of and affects the localization of RELA protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of RELA protein]; Curcumin inhibits the reaction [TNF protein affects the localization of RELA protein]; Curcumin inhibits the reaction [TNF protein results in increased acetylation of RELA protein]; Curcumin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Curcumin inhibits the reaction [TNF protein results in increased activity of RELA protein]; Curcumin inhibits the reaction [TNF protein results in increased localization of and results in increased activity of RELA protein]; Curcumin inhibits the reaction [TNF protein results in increased localization of RELA protein]; Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]; Curcumin results in decreased activity of [NFKB1 protein binds to RELA protein]; Curcumin results in decreased expression of and results in decreased activity of RELA protein; Curcumin results in decreased phosphorylation of and affects the localization of RELA protein; Dithiothreitol inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased activity of RELA protein]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased activity of RELA protein]]; TNFSF10 protein promotes the reaction [Curcumin results in decreased activity of RELA protein]; zinc protoporphyrin inhibits the reaction [Curcumin inhibits the reaction [quinocetone results in increased expression of RELA mRNA]]
[Curcumin co-treated with Gemcitabine] results in decreased expression of RELA protein; Curcumin analog inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; Curcumin inhibits the reaction [[NFKB1 protein binds to RELA protein] which results in increased expression of ABCB1B mRNA]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of RELA protein]; Curcumin inhibits the reaction [Chloranil affects the localization of RELA protein modified form]; Curcumin inhibits the reaction [Chloranil results in increased expression of RELA protein]; Curcumin inhibits the reaction [Dibutyl Phthalate results in increased phosphorylation of RELA protein]; Curcumin inhibits the reaction [NFKB1 protein binds to RELA protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of RELA protein]; Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]
Curcumin results in decreased expression of RELA protein
Curcumin results in increased activity of RELA protein
2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in decreased expression of RELA protein]; [Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in increased expression of and results in increased phosphorylation of RELA protein]; [Curcumin binds to carboxymethyl-chitosan analog] which results in decreased expression of and results in decreased phosphorylation of RELA protein; CD40 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]]; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of RELA protein]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of RELA protein]; Curcumin inhibits the reaction [Doxorubicin results in increased expression of RELA protein]; Curcumin inhibits the reaction [Ethanol promotes the reaction [Lipopolysaccharides results in increased activity of [RELA protein binds to NFKB1 protein]]]; Curcumin inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]; Curcumin inhibits the reaction [Streptozocin affects the localization of RELA protein]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of RELA protein]; Curcumin results in increased expression of and results in increased activity of RELA protein; ICAM1 protein affects the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]]; NFE2L2 protein promotes the reaction [Curcumin results in increased activity of RELA protein]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in increased expression of RELA protein]]
Curcumin affects the activity of RELA protein
Curcumin results in increased expression of RELA
Curcumin results in decreased localization of RELA protein
Curcumin results in decreased expression of RELA; Curcumin results in decreased expression of RELA mRNA; Curcumin results in decreased expression of RELA protein		 CTD PMID:12216086 PMID:12388107 PMID:15489888 PMID:15911101 PMID:16023083 More... NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of RELB mRNA] CTD PMID:23452621 NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363 		JBrowse link
G Reln reelin multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [bisphenol A results in decreased expression of RELN mRNA]
Curcumin results in increased expression of RELN mRNA		 CTD PMID:25963729 NCBI chr 5:22,089,452...22,549,703
Ensembl chr 5:22,089,452...22,549,700 		JBrowse link
G Retnlb resistin like beta multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RETNLB mRNA] CTD PMID:18200517 NCBI chr16:48,637,219...48,639,255
Ensembl chr16:48,637,219...48,639,255 		JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit increases expression ISO Curcumin results in increased expression of REV3L protein CTD PMID:19137819 NCBI chr10:39,607,557...39,751,207
Ensembl chr10:39,608,114...39,751,207 		JBrowse link
G Rfxap regulatory factor X-associated protein decreases expression ISO Curcumin results in decreased expression of RFXAP mRNA CTD PMID:17999991 NCBI chr 3:54,710,536...54,715,212
Ensembl chr 3:54,710,536...54,715,212 		JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO Curcumin results in increased expression of RGS16 mRNA CTD PMID:17198877 NCBI chr 1:153,616,099...153,621,212
Ensembl chr 1:153,616,095...153,621,214 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 decreases expression ISO Curcumin results in decreased expression of RGS4 mRNA CTD PMID:21594647 NCBI chr 1:169,569,046...169,575,211
Ensembl chr 1:169,569,046...169,575,211 		JBrowse link
G Rgs7 regulator of G protein signaling 7 decreases expression ISO Curcumin results in decreased expression of RGS7 mRNA CTD PMID:17999991 NCBI chr 1:174,886,642...175,320,287
Ensembl chr 1:174,886,653...175,320,066 		JBrowse link
G Rhoa ras homolog family member A decreases expression ISO Curcumin analog results in decreased expression of RHOA mRNA CTD PMID:26409325 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133 		JBrowse link
G Rhob ras homolog family member B decreases expression ISO Curcumin analog results in decreased expression of RHOB mRNA CTD PMID:26409325 NCBI chr12:8,547,661...8,550,009
Ensembl chr12:8,547,661...8,550,009 		JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 decreases expression ISO Curcumin results in decreased expression of RIMS2 mRNA CTD PMID:17999991 NCBI chr15:39,061,681...39,547,768
Ensembl chr15:39,061,656...39,547,768 		JBrowse link
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of RIPK1 mRNA] CTD PMID:23452621 NCBI chr13:34,181,072...34,219,153
Ensembl chr13:34,186,346...34,221,130 		JBrowse link
G Rpl31 ribosomal protein L31 increases expression ISO Curcumin results in increased expression of RPL31 mRNA CTD PMID:17999991 NCBI chr 1:39,406,987...39,410,992
Ensembl chr 1:39,406,923...39,410,992 		JBrowse link
G Rps6 ribosomal protein S6 multiple interactions
decreases phosphorylation		 ISO calyculin A inhibits the reaction [Curcumin results in decreased phosphorylation of RPS6 protein]; Curcumin inhibits the reaction [bisphenol A results in increased phosphorylation of and results in increased expression of RPS6 protein]; Curcumin results in decreased phosphorylation of and results in decreased expression of RPS6 protein CTD PMID:18790744 PMID:21450334 PMID:23222814 PMID:34634291 NCBI chr 4:86,772,336...86,775,604
Ensembl chr 4:86,772,897...86,775,649 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 decreases phosphorylation
multiple interactions		 ISO
EXP		 Curcumin results in decreased phosphorylation of RPS6KB1 protein
Curcumin inhibits the reaction [Thioacetamide results in increased phosphorylation of RPS6KB1 protein]
Curcumin analog inhibits the reaction [Oxygen deficiency results in increased phosphorylation of RPS6KB1 protein]		 CTD PMID:18790744 PMID:20554536 PMID:27363783 PMID:34634291 NCBI chr11:86,389,695...86,435,711
Ensembl chr11:86,389,697...86,435,631 		JBrowse link
G Rreb1 ras responsive element binding protein 1 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of RREB1 mRNA] CTD PMID:18200517 NCBI chr13:37,962,362...38,135,981
Ensembl chr13:37,962,376...38,135,981 		JBrowse link
G Rtkn rhotekin multiple interactions ISO Curcumin inhibits the reaction [RTKN protein results in decreased susceptibility to Butyrates]; Curcumin inhibits the reaction [RTKN protein results in decreased susceptibility to Fluorouracil]; Curcumin inhibits the reaction [RTKN protein results in decreased susceptibility to Paclitaxel] CTD PMID:15480428 NCBI chr 6:83,112,485...83,129,560
Ensembl chr 6:83,112,444...83,129,560 		JBrowse link
G Runx2 runt related transcription factor 2 decreases expression ISO Curcumin results in decreased expression of RUNX2 protein CTD PMID:15129424 NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684 		JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO Curcumin promotes the reaction [VDR protein binds to RXRA protein] CTD PMID:20153625 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969 		JBrowse link
G S100a8 S100 calcium binding protein A8 (calgranulin A) multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of S100A8 mRNA] CTD PMID:18200517 NCBI chr 3:90,576,378...90,577,341
Ensembl chr 3:90,576,285...90,577,342 		JBrowse link
G S100a9 S100 calcium binding protein A9 (calgranulin B) multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of S100A9 mRNA] CTD PMID:18200517 NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028 		JBrowse link
G S100g S100 calcium binding protein G affects expression ISO Curcumin affects the expression of S100G mRNA CTD PMID:18539377 NCBI chr  X:161,744,988...161,747,595
Ensembl chr  X:161,744,988...161,747,595 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 affects expression EXP Curcumin affects the expression of SCARB1 mRNA CTD PMID:27208389 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158 		JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 decreases expression
affects expression		 ISO
EXP		 Curcumin results in decreased expression of SCD mRNA
Curcumin affects the expression of SCD1 mRNA; Curcumin affects the expression of SCD1 protein		 CTD PMID:27208389 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318 		JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 decreases expression ISO Curcumin results in decreased expression of SCD2 mRNA
Curcumin results in decreased expression of SCD mRNA		 CTD PMID:20816778 PMID:27208389 NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303 		JBrowse link
G Scrn2 secernin 2 decreases expression ISO Curcumin results in decreased expression of SCRN2 mRNA CTD PMID:17198877 NCBI chr11:96,920,717...96,924,786
Ensembl chr11:96,920,764...96,924,784 		JBrowse link
G Sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) decreases expression ISO Curcumin results in decreased expression of SDHA mRNA CTD PMID:17198877 NCBI chr13:74,470,374...74,498,359
Ensembl chr13:74,470,373...74,498,399 		JBrowse link
G Sele selectin, endothelial cell multiple interactions
affects expression		 ISO Curcumin inhibits the reaction [F2 protein results in increased expression of SELE protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of SELE protein]
Curcumin inhibits the reaction [Particulate Matter results in increased expression of SELE protein]; Curcumin inhibits the reaction [titanium dioxide results in increased expression of SELE protein]
Curcumin affects the expression of SELE protein		 CTD PMID:17960570 PMID:18565277 PMID:29244817 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246 		JBrowse link
G Sell selectin, lymphocyte multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of SELL mRNA] CTD PMID:23452621 NCBI chr 1:163,889,556...163,908,354
Ensembl chr 1:163,889,551...163,911,750 		JBrowse link
G Selp selectin, platelet multiple interactions ISO Curcumin inhibits the reaction [F2 protein results in increased expression of SELP protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of SELP protein]
Curcumin inhibits the reaction [Particulate Matter results in increased expression of SELP protein]; Curcumin inhibits the reaction [titanium dioxide results in increased expression of SELP protein]		 CTD PMID:18565277 PMID:29244817 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595 		JBrowse link
G Septin7 septin 7 increases expression ISO Curcumin results in increased expression of SEPTIN7 mRNA CTD PMID:16101141 NCBI chr 9:25,163,287...25,219,867
Ensembl chr 9:25,163,735...25,219,867 		JBrowse link
G Serpina3b serine (or cysteine) peptidase inhibitor, clade A, member 3B multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SERPINA3 mRNA] CTD PMID:18200517 NCBI chr12:104,094,245...104,105,805
Ensembl chr12:104,094,255...104,105,804 		JBrowse link
G Serpinb2 serine (or cysteine) peptidase inhibitor, clade B, member 2 increases expression ISO Curcumin results in increased expression of SERPINB2 mRNA CTD PMID:15713895 NCBI chr 1:107,439,153...107,453,330
Ensembl chr 1:107,439,153...107,463,208 		JBrowse link
G Serpinb5 serine (or cysteine) peptidase inhibitor, clade B, member 5 increases expression
multiple interactions		 ISO [Curcumin results in increased expression of SERPINB5] which results in increased expression of TP53 protein; Curcumin results in increased expression of SERPINB5 mRNA; Curcumin results in increased expression of SERPINB5 protein
[Curcumin results in increased expression of SERPINB5] which results in decreased expression of BCL2 protein		 CTD PMID:17290611 PMID:19944674 NCBI chr 1:106,788,905...106,811,078
Ensembl chr 1:106,788,903...106,811,078 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 increases expression
multiple interactions		 ISO
EXP		 Curcumin results in increased expression of SERPINE1 mRNA
Curcumin inhibits the reaction [Bleomycin results in increased expression of SERPINE1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of SERPINE1 protein]		 CTD PMID:15713895 PMID:35716765 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SERPINE2 mRNA] CTD PMID:18200517 NCBI chr 1:79,772,038...79,836,382
Ensembl chr 1:79,771,914...79,838,897 		JBrowse link
G Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 multiple interactions ISO Curcumin inhibits the reaction [Thioacetamide results in increased expression of SERPINH1 mRNA] CTD PMID:24704557 NCBI chr 7:98,994,583...99,002,321
Ensembl chr 7:98,994,583...99,002,446 		JBrowse link
G Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) increases expression ISO Curcumin results in increased expression of SFPQ mRNA CTD PMID:17198877 NCBI chr 4:126,914,504...126,944,894
Ensembl chr 4:126,915,117...126,930,806 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of SFRP2 mRNA
Curcumin inhibits the reaction [bisphenol A results in increased expression of SFRP2 mRNA]		 CTD PMID:25963729 NCBI chr 3:83,673,628...83,681,621
Ensembl chr 3:83,673,628...83,681,623 		JBrowse link
G Sfrp5 secreted frizzled-related sequence protein 5 decreases expression ISO Curcumin results in decreased expression of SFRP5 mRNA CTD PMID:16101141 NCBI chr19:42,186,410...42,190,691
Ensembl chr19:42,186,410...42,190,691 		JBrowse link
G Sfxn1 sideroflexin 1 decreases expression ISO Curcumin results in decreased expression of SFXN1 mRNA CTD PMID:18421014 NCBI chr13:54,225,675...54,262,365
Ensembl chr13:54,225,888...54,262,361 		JBrowse link
G Shh sonic hedgehog multiple interactions ISO [Arsenic Trioxide co-treated with Curcumin] inhibits the reaction [Cisplatin results in increased expression of SHH mRNA]; Curcumin inhibits the reaction [Cisplatin results in increased expression of SHH mRNA] CTD PMID:31612257 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254 		JBrowse link
G Sim2 single-minded family bHLH transcription factor 2 multiple interactions ISO Curcumin inhibits the reaction [Glucose results in increased expression of SIM2 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of SIM2 protein] CTD PMID:23333261 NCBI chr16:93,885,963...93,927,891
Ensembl chr16:93,885,790...93,927,891 		JBrowse link
G Sirt1 sirtuin 1 increases expression
multiple interactions		 EXP
ISO		 Curcumin results in increased expression of SIRT1 mRNA
Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of SIRT1 mRNA]; Curcumin inhibits the reaction [aristolochic acid I results in decreased expression of SIRT1 protein]; Curcumin inhibits the reaction [Cyclosporine results in decreased expression of SIRT1 protein]		 CTD PMID:18403477 PMID:32569592 PMID:36037877 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Sirt3 sirtuin 3 multiple interactions ISO Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with Tobacco Smoke Pollution] results in decreased expression of SIRT3 mRNA]; Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with Tobacco Smoke Pollution] results in decreased expression of SIRT3 protein]; Curcumin inhibits the reaction [Cisplatin results in decreased expression of and results in decreased activity of SIRT3 protein]
Curcumin inhibits the reaction [[GYY 4137 results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 mRNA]]		 CTD PMID:26422756 PMID:28698153 PMID:28951138 NCBI chr 7:140,443,576...140,462,222
Ensembl chr 7:140,443,579...140,462,222 		JBrowse link
G Sirt6 sirtuin 6 multiple interactions ISO Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of SIRT6 mRNA]; Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of SIRT6 protein]; SIRT6 protein promotes the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 mRNA]]; SIRT6 protein promotes the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in decreased expression of ABCA1 protein]]; SIRT6 protein promotes the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of CCL2 protein]]; SIRT6 protein promotes the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of IL6 protein]]; SIRT6 protein promotes the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of TNF protein]] CTD PMID:33952798 NCBI chr10:81,457,621...81,463,631
Ensembl chr10:81,457,619...81,463,631 		JBrowse link
G Sirt7 sirtuin 7 decreases expression ISO Curcumin results in decreased expression of SIRT7 CTD PMID:25644192 NCBI chr11:120,509,197...120,515,840
Ensembl chr11:120,509,198...120,516,066 		JBrowse link
G Skap2 src family associated phosphoprotein 2 decreases expression EXP Curcumin results in decreased expression of SKAP2 mRNA CTD PMID:19555370 NCBI chr 6:51,836,145...51,989,529
Ensembl chr 6:51,834,402...51,989,529 		JBrowse link
G Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 increases expression EXP Curcumin results in increased expression of SLC11A2 mRNA CTD PMID:24634837 NCBI chr15:100,285,779...100,322,090
Ensembl chr15:100,285,779...100,322,953 		JBrowse link
G Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 decreases expression EXP Curcumin results in decreased expression of SLC16A1 protein CTD PMID:21397623 NCBI chr 3:104,545,980...104,565,778
Ensembl chr 3:104,545,984...104,565,778 		JBrowse link
G Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 multiple interactions ISO Curcumin inhibits the reaction [sodium arsenite results in decreased expression of SLC18A2 protein] CTD PMID:27966075 NCBI chr19:59,249,310...59,284,444
Ensembl chr19:59,249,328...59,284,444 		JBrowse link
G Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 multiple interactions ISO Curcumin inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA] CTD PMID:23267840 NCBI chr15:8,663,608...8,742,648
Ensembl chr15:8,663,608...8,740,248 		JBrowse link
G Slc20a1 solute carrier family 20, member 1 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SLC20A1 mRNA] CTD PMID:18200517 NCBI chr 2:129,038,662...129,053,535
Ensembl chr 2:129,040,684...129,053,536 		JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 decreases expression
multiple interactions		 EXP
ISO		 Curcumin results in decreased expression of SLC2A1 mRNA
Curcumin results in decreased expression of SLC2A1 protein
ATF4 inhibits the reaction [Curcumin results in decreased expression of SLC2A1 protein]; Curcumin inhibits the reaction [4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine results in increased phosphorylation of SLC2A1 protein]		 CTD PMID:21397623 PMID:36640941 NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180 		JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 decreases expression
multiple interactions		 EXP
ISO		 Curcumin results in decreased expression of SLC2A2 mRNA
Curcumin inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]		 CTD PMID:21397623 PMID:25541178 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508 		JBrowse link
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 decreases expression EXP Curcumin results in decreased expression of SLC2A3 mRNA CTD PMID:21397623 NCBI chr 6:122,704,783...122,779,149
Ensembl chr 6:122,704,768...122,778,599 		JBrowse link
G Slc2a5 solute carrier family 2 (facilitated glucose transporter), member 5 decreases expression EXP Curcumin results in decreased expression of SLC2A5 mRNA CTD PMID:21397623 NCBI chr 4:150,203,801...150,228,625
Ensembl chr 4:150,203,740...150,228,626 		JBrowse link
G Slc30a1 solute carrier family 30 (zinc transporter), member 1 increases expression ISO Curcumin results in increased expression of SLC30A1 mRNA CTD PMID:17999991 NCBI chr 1:191,638,810...191,645,359
Ensembl chr 1:191,638,879...191,645,359 		JBrowse link
G Slc30a10 solute carrier family 30, member 10 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SLC30A10 mRNA] CTD PMID:18200517 NCBI chr 1:185,187,045...185,200,959
Ensembl chr 1:185,187,045...185,200,959 		JBrowse link
G Slc37a4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 decreases expression ISO Curcumin results in decreased expression of SLC37A4 mRNA CTD PMID:16777101 NCBI chr 9:44,308,243...44,314,263
Ensembl chr 9:44,308,149...44,314,265 		JBrowse link
G Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 increases expression ISO
EXP		 Curcumin results in increased expression of SLC3A2 mRNA CTD PMID:17198877 PMID:19183254 NCBI chr19:8,684,931...8,700,733
Ensembl chr19:8,684,246...8,700,733 		JBrowse link
G Slc48a1 solute carrier family 48 (heme transporter), member 1 increases expression ISO Curcumin results in increased expression of SLC48A1 mRNA CTD PMID:17198877 NCBI chr15:97,682,246...97,690,573
Ensembl chr15:97,676,401...97,690,573 		JBrowse link
G Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 multiple interactions ISO Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of SLC6A3 protein] CTD PMID:30463061 NCBI chr13:73,684,270...73,726,791
Ensembl chr13:73,684,866...73,726,791 		JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 increases expression ISO
EXP		 Curcumin results in increased expression of SLC7A11 mRNA CTD PMID:17999991 PMID:19183254 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063 		JBrowse link
G Slco1a5 solute carrier organic anion transporter family, member 1a5 increases expression ISO Curcumin results in increased expression of SLCO1A2 mRNA CTD PMID:18421014 NCBI chr 6:142,179,953...142,268,707
Ensembl chr 6:142,179,953...142,268,707 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SLPI mRNA] CTD PMID:18200517 NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015 		JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO Curcumin inhibits the reaction [AGT protein results in increased phosphorylation of SMAD2 protein] CTD PMID:26648693 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO Curcumin inhibits the reaction [[SMAD4 protein binds to SMAD3 protein] which binds to PPARG promoter]; Curcumin inhibits the reaction [AGT protein results in increased phosphorylation of SMAD3 protein]; Curcumin inhibits the reaction [Thioacetamide results in increased phosphorylation of SMAD3 protein]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in increased phosphorylation of SMAD3 protein]] CTD PMID:16959952 PMID:26648693 PMID:32718261 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276 		JBrowse link
G Smad4 SMAD family member 4 multiple interactions
decreases expression		 ISO
EXP		 Curcumin inhibits the reaction [[SMAD4 protein binds to SMAD3 protein] which binds to PPARG promoter]
Curcumin results in decreased expression of SMAD4 mRNA		 CTD PMID:16959952 PMID:27237783 NCBI chr18:73,767,861...73,836,862
Ensembl chr18:73,772,080...73,836,851 		JBrowse link
G Smo smoothened, frizzled class receptor multiple interactions ISO [Arsenic Trioxide co-treated with Curcumin] inhibits the reaction [Cisplatin results in increased expression of SMO mRNA]; Curcumin inhibits the reaction [Cisplatin results in increased expression of SMO mRNA] CTD PMID:31612257 NCBI chr 6:29,735,480...29,761,359
Ensembl chr 6:29,735,502...29,761,364 		JBrowse link
G Smpx small muscle protein, X-linked multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of SMPX mRNA] CTD PMID:18200517 NCBI chr  X:156,481,969...156,535,587
Ensembl chr  X:156,481,906...156,535,587 		JBrowse link
G Snai1 snail family zinc finger 1 multiple interactions ISO Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SNAI1 protein]; Curcumin inhibits the reaction [Trichloroethylene results in increased expression of SNAI1 protein] CTD PMID:25656647 PMID:34233590 NCBI chr 2:167,380,115...167,384,734
Ensembl chr 2:167,380,115...167,384,734 		JBrowse link
G Snai2 snail family zinc finger 2 decreases expression ISO Curcumin results in decreased expression of SNAI2 protein CTD PMID:19573523 NCBI chr16:14,523,716...14,527,259
Ensembl chr16:14,523,716...14,527,249 		JBrowse link
G Snca synuclein, alpha multiple interactions EXP [Curcumin co-treated with Niacin co-treated with ZM 241385] inhibits the reaction [Rotenone results in increased expression of SNCA protein]; Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SNCA protein]; Curcumin inhibits the reaction [Rotenone results in increased expression of SNCA protein] CTD PMID:31187328 PMID:31820278 NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839 		JBrowse link
G Snhg12 small nucleolar RNA host gene 12 decreases expression ISO Curcumin results in decreased expression of SNHG12 mRNA CTD PMID:17999991 NCBI chr 4:132,035,989...132,038,335
Ensembl chr 4:132,035,932...132,038,762 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression EXP Curcumin results in decreased expression of SOCS3 mRNA CTD PMID:18403477 PMID:25822711 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 decreases expression EXP Curcumin results in decreased expression of SOCS5 protein CTD PMID:21397623 NCBI chr17:87,414,707...87,445,153
Ensembl chr17:87,415,107...87,445,267 		JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions
increases expression		 ISO
EXP		 [Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in decreased expression of SOD1 mRNA]; [Curcumin co-treated with Vitamin E] inhibits the reaction [Thyroxine results in increased activity of SOD1 protein]; [Curcumin co-treated with Vitamin E] promotes the reaction [Thyroxine results in decreased activity of SOD1 protein]; Curcumin inhibits the reaction [aristolochic acid I results in decreased activity of SOD1 protein]; Curcumin inhibits the reaction [Thyroxine results in decreased expression of SOD1 mRNA]; Curcumin inhibits the reaction [Thyroxine results in increased activity of SOD1 protein]; Curcumin promotes the reaction [Thyroxine results in decreased activity of SOD1 protein]
Curcumin results in increased expression of SOD1 protein
Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of SOD1 mRNA]; Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of SOD1 protein]; Curcumin inhibits the reaction [quinocetone results in decreased activity of SOD1 protein]
Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of SOD1 mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of SOD1 mRNA]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of SOD1 mRNA]		 CTD PMID:19914224 PMID:25996037 PMID:30934151 PMID:31521693 PMID:35063475 More... NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial affects expression
increases expression
multiple interactions		 ISO
EXP		 Curcumin affects the expression of SOD2 mRNA; Curcumin affects the expression of SOD2 protein
Curcumin results in increased expression of SOD2 protein
Curcumin results in increased expression of SOD2 mRNA; Curcumin results in increased expression of SOD2 protein
2-methoxyestradiol inhibits the reaction [Curcumin results in increased expression of SOD2 mRNA]
Curcumin analog inhibits the reaction [[Sodium Cholate co-treated with Deoxycholic Acid co-treated with Glycocholic Acid co-treated with Taurocholic Acid] results in decreased expression of and results in decreased activity of SOD2 protein]; Curcumin analog inhibits the reaction [[Sodium Cholate co-treated with Deoxycholic Acid co-treated with Glycocholic Acid co-treated with Taurocholic Acid] results in increased expression of and results in decreased activity of SOD2 protein]; Curcumin analog promotes the reaction [[Sodium Cholate co-treated with Deoxycholic Acid co-treated with Glycocholic Acid co-treated with Taurocholic Acid] results in increased expression of SOD2 protein]; Curcumin inhibits the reaction [Hydrogen Peroxide results in decreased expression of SOD2 mRNA]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of SOD2 protein]; Curcumin promotes the reaction [sodium arsenite results in decreased expression of SOD2 protein]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in decreased expression of SOD2 protein]]
[Vitamin E co-treated with Curcumin] inhibits the reaction [Thyroxine results in decreased expression of SOD2 mRNA]; Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with Tobacco Smoke Pollution] results in decreased activity of SOD2 protein]; Curcumin inhibits the reaction [Thyroxine results in decreased activity of SOD2 protein]; Curcumin promotes the reaction [Thyroxine results in increased expression of SOD2 protein]		 CTD PMID:11543823 PMID:18299980 PMID:19914224 PMID:22316666 PMID:23452621 More... NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Sox2 SRY (sex determining region Y)-box 2 increases expression EXP Curcumin results in increased expression of SOX2 mRNA; Curcumin results in increased expression of SOX2 protein CTD PMID:25822711 NCBI chr 3:34,704,144...34,706,610
Ensembl chr 3:34,704,554...34,706,610 		JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 multiple interactions
increases expression		 ISO [Curcumin co-treated with resveratrol] results in increased expression of SOX9 protein
Curcumin results in increased expression of SOX9 protein		 CTD PMID:19889203 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586 		JBrowse link
G Sp1 trans-acting transcription factor 1 decreases expression ISO Curcumin results in decreased expression of SP1 protein CTD PMID:18347134 PMID:18593936 NCBI chr15:102,314,751...102,344,839
Ensembl chr15:102,314,578...102,344,839 		JBrowse link
G Sp3 trans-acting transcription factor 3 decreases expression ISO Curcumin results in decreased expression of SP3 protein CTD PMID:18593936 NCBI chr 2:72,766,774...72,810,790
Ensembl chr 2:72,766,771...72,810,790 		JBrowse link
G Sp4 trans-acting transcription factor 4 decreases expression ISO Curcumin results in decreased expression of SP4 protein CTD PMID:18593936 NCBI chr12:118,195,421...118,265,211
Ensembl chr12:118,198,668...118,265,175 		JBrowse link
G Sparc secreted acidic cysteine rich glycoprotein multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SPARC mRNA] CTD PMID:18200517 NCBI chr11:55,284,985...55,310,906
Ensembl chr11:55,285,326...55,314,009 		JBrowse link
G Spib Spi-B transcription factor (Spi-1/PU.1 related) increases expression ISO Curcumin results in increased expression of SPIB mRNA CTD PMID:17198877 NCBI chr 7:44,175,419...44,181,511
Ensembl chr 7:44,175,417...44,181,495 		JBrowse link
G Spock1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 increases expression ISO Curcumin results in increased expression of SPOCK1 mRNA CTD PMID:21594647 NCBI chr13:57,569,008...58,056,194
Ensembl chr13:57,569,008...58,056,146 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO Curcumin inhibits the reaction [Cadmium Chloride results in increased export of SPP1 protein] CTD PMID:29421648 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Sqle squalene epoxidase decreases expression
affects expression		 ISO
EXP		 Curcumin results in decreased expression of SQLE mRNA
Curcumin affects the expression of SQLE mRNA		 CTD PMID:27208389 NCBI chr15:59,186,941...59,203,042
Ensembl chr15:59,186,926...59,203,041 		JBrowse link
G Sqstm1 sequestosome 1 decreases expression
increases expression
multiple interactions		 ISO
EXP		 Curcumin results in decreased expression of SQSTM1 protein
Curcumin results in increased expression of SQSTM1 protein
4-phenylbutyric acid inhibits the reaction [Curcumin results in decreased expression of SQSTM1 protein]; Curcumin inhibits the reaction [4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine results in increased phosphorylation of SQSTM1 protein]; Curcumin inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein]; Curcumin inhibits the reaction [Tunicamycin results in decreased expression of SQSTM1 protein]; Curcumin promotes the reaction [sodium arsenite results in increased expression of SQSTM1 protein]; NFE2L2 protein affects the reaction [Curcumin promotes the reaction [sodium arsenite results in increased expression of SQSTM1 protein]]		 CTD PMID:34634291 PMID:34758851 PMID:36640941 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654 		JBrowse link
G Src Rous sarcoma oncogene decreases expression
multiple interactions
decreases activity		 ISO
EXP		 Curcumin results in decreased expression of SRC protein
[Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] which results in decreased activity of SRC protein
[Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of SRC protein]
Curcumin analog results in decreased activity of SRC protein; Curcumin results in decreased activity of SRC protein		 CTD PMID:16959222 PMID:33617879 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 affects expression
multiple interactions
decreases expression		 EXP
ISO		 Curcumin affects the expression of SREBF1 mRNA; Curcumin affects the expression of SREBF1 protein
Curcumin inhibits the reaction [bisphenol A results in increased expression of SREBF1 mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased expression of SREBF1 protein]
Curcumin results in decreased expression of SREBF1 mRNA		 CTD PMID:27208389 PMID:37701206 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407 		JBrowse link
G Srebf2 sterol regulatory element binding factor 2 affects expression
multiple interactions
decreases expression		 EXP
ISO		 Curcumin affects the expression of SREBF2 mRNA; Curcumin affects the expression of SREBF2 protein
Curcumin inhibits the reaction [bisphenol A results in increased expression of SREBF2 protein]
Curcumin results in decreased expression of SREBF2 mRNA		 CTD PMID:27208389 PMID:37701206 NCBI chr15:82,031,455...82,089,580
Ensembl chr15:82,031,382...82,089,580 		JBrowse link
G Srm spermidine synthase multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SRM mRNA] CTD PMID:18200517 NCBI chr 4:148,675,970...148,679,076
Ensembl chr 4:148,675,960...148,679,450 		JBrowse link
G Srsf1 serine and arginine-rich splicing factor 1 increases expression ISO Curcumin results in increased expression of SRSF1 mRNA CTD PMID:17999991 NCBI chr11:87,937,325...87,944,583
Ensembl chr11:87,938,199...87,944,581 		JBrowse link
G Srsf2 serine and arginine-rich splicing factor 2 increases expression ISO Curcumin results in increased expression of SRSF2 mRNA CTD PMID:17198877 NCBI chr11:116,740,723...116,744,511
Ensembl chr11:116,740,727...116,743,920 		JBrowse link
G Srsf3 serine and arginine-rich splicing factor 3 increases expression ISO Curcumin results in increased expression of SRSF3 mRNA CTD PMID:17198877 NCBI chr17:29,251,634...29,262,346
Ensembl chr17:29,251,602...29,262,347 		JBrowse link
G Srsf5 serine and arginine-rich splicing factor 5 decreases expression ISO Curcumin results in decreased expression of SRSF5 mRNA CTD PMID:17999991 NCBI chr12:80,992,308...80,997,277
Ensembl chr12:80,992,278...80,997,281 		JBrowse link
G Srsf6 serine and arginine-rich splicing factor 6 increases expression ISO Curcumin results in increased expression of SRSF6 mRNA CTD PMID:17198877 NCBI chr 2:162,773,428...162,779,041
Ensembl chr 2:162,773,448...162,779,041 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO
EXP		 Curcumin inhibits the reaction [IFNG protein results in increased expression of and results in increased phosphorylation of STAT1 protein]
Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT1 protein]		 CTD PMID:16959222 PMID:21811692 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
decreases expression
increases phosphorylation
decreases phosphorylation		 ISO
EXP		 Arsenic Trioxide promotes the reaction [Curcumin results in decreased expression of STAT3 protein]; Bortezomib promotes the reaction [Curcumin results in decreased phosphorylation of STAT3 protein]; Curcumin inhibits the reaction [IFNG protein results in increased expression of and results in increased phosphorylation of STAT3 protein]; Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of STAT3 protein]; Curcumin inhibits the reaction [Trichloroethylene results in increased phosphorylation of STAT3 protein]
[Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and affects the localization of STAT3 protein]
Curcumin analog inhibits the reaction [Copper Sulfate results in increased expression of STAT3 protein]; Curcumin inhibits the reaction [bisphenol A results in increased expression of STAT3 mRNA]; Curcumin inhibits the reaction [Copper Sulfate results in increased expression of STAT3 protein]
Curcumin results in decreased expression of STAT3 mRNA
Curcumin results in increased phosphorylation of STAT3 protein
Curcumin results in decreased expression of STAT3 mRNA; Curcumin results in decreased expression of STAT3 protein		 CTD PMID:16959222 PMID:17666914 PMID:19383353 PMID:20816778 PMID:25822711 More... NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 multiple interactions ISO Curcumin promotes the reaction [IFNB1 protein results in increased phosphorylation of STAT4 protein] CTD PMID:17979888 NCBI chr 1:52,026,265...52,146,348
Ensembl chr 1:52,026,307...52,146,348 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A increases cleavage
decreases expression		 ISO Curcumin results in increased cleavage of STAT5A protein
Curcumin results in decreased expression of STAT5A protein		 CTD PMID:16959222 NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B increases cleavage
decreases expression		 ISO Curcumin results in increased cleavage of STAT5B protein
Curcumin results in decreased expression of STAT5B protein		 CTD PMID:16959222 NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550 		JBrowse link
G Sts steroid sulfatase decreases expression ISO Curcumin results in decreased expression of STS mRNA CTD PMID:17198877 NCBI chr  X:168,856,332...169,015,037
Ensembl chr  X:168,909,030...169,014,924 		JBrowse link
G Stx3 syntaxin 3 multiple interactions EXP [Docosahexaenoic Acids co-treated with Curcumin] results in increased expression of STX3 mRNA CTD PMID:22911773 NCBI chr19:11,752,482...11,798,933
Ensembl chr19:11,752,482...11,796,767 		JBrowse link
G Sulf1 sulfatase 1 increases expression ISO
EXP		 Curcumin results in increased expression of SULF1 mRNA; Curcumin results in increased expression of SULF1 protein CTD PMID:21594647 NCBI chr 1:12,762,421...12,946,090
Ensembl chr 1:12,762,501...12,931,416 		JBrowse link
G Sulf2 sulfatase 2 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of SULF2 mRNA] CTD PMID:18200517 NCBI chr 2:165,915,819...165,997,603
Ensembl chr 2:165,915,009...165,997,583 		JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit decreases expression ISO Curcumin results in decreased expression of SUZ12 mRNA CTD PMID:18421014 NCBI chr11:79,883,932...79,924,949
Ensembl chr11:79,883,932...79,924,949 		JBrowse link
G Sycp2 synaptonemal complex protein 2 increases expression ISO Curcumin results in increased expression of SYCP2 mRNA CTD PMID:18421014 NCBI chr 2:177,987,088...178,051,580
Ensembl chr 2:177,987,086...178,049,478 		JBrowse link
G Syn2 synapsin II multiple interactions EXP Curcumin inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SYN2 protein] CTD PMID:32735850 NCBI chr 6:115,111,863...115,259,587
Ensembl chr 6:115,111,863...115,258,967 		JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 homolog (rat) multiple interactions ISO Curcumin inhibits the reaction [sodium arsenite results in increased expression of SYNGAP1 protein] CTD PMID:29723552 NCBI chr17:27,160,186...27,191,408
Ensembl chr17:27,160,227...27,191,408 		JBrowse link
G T brachyury, T-box transcription factor T decreases expression EXP Curcumin results in decreased expression of T mRNA CTD PMID:27237783 NCBI chr17:8,653,255...8,661,328
Ensembl chr17:8,653,255...8,661,328 		JBrowse link
G Tada3 transcriptional adaptor 3 affects expression ISO Curcumin affects the expression of TADA3 mRNA CTD PMID:18539377 NCBI chr 6:113,343,594...113,354,799
Ensembl chr 6:113,342,986...113,354,844 		JBrowse link
G Taldo1 transaldolase 1 increases expression ISO Curcumin results in increased expression of TALDO1 mRNA CTD PMID:18299980 NCBI chr 7:140,972,073...140,982,889
Ensembl chr 7:140,972,112...140,982,881 		JBrowse link
G Tbc1d1 TBC1 domain family, member 1 decreases expression ISO Curcumin results in decreased expression of TBC1D1 mRNA CTD PMID:17198877 NCBI chr 5:64,313,648...64,508,829
Ensembl chr 5:64,313,648...64,508,829 		JBrowse link
G Tbc1d8 TBC1 domain family, member 8 increases expression ISO Curcumin results in increased expression of TBC1D8 mRNA CTD PMID:17999991 NCBI chr 1:39,410,576...39,517,860
Ensembl chr 1:39,410,573...39,517,836 		JBrowse link
G Tbk1 TANK-binding kinase 1 multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of TBK1 mRNA] CTD PMID:23452621 NCBI chr10:121,382,360...121,422,699
Ensembl chr10:121,382,360...121,422,692 		JBrowse link
G Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box multiple interactions ISO Curcumin inhibits the reaction [CTNNB1 protein binds to TCF7L2 protein]; Curcumin results in decreased activity of [CTNNB1 protein binds to TCF7L2 protein] CTD PMID:19294764 NCBI chr19:55,730,227...55,922,091
Ensembl chr19:55,730,252...55,922,086 		JBrowse link
G Tert telomerase reverse transcriptase decreases activity ISO Curcumin results in decreased activity of TERT protein CTD PMID:17096185 NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962 		JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 increases expression ISO curcumin increases expression of TET2 mRNA and protein in stomach RGD PMID:33058920 RGD:150429654 NCBI chr 3:133,169,438...133,250,882
Ensembl chr 3:133,169,440...133,250,900 		JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions ISO [Curcumin co-treated with Potassium Dichromate] results in increased expression of TFAM protein CTD PMID:32980475 NCBI chr10:71,061,298...71,074,157
Ensembl chr10:71,061,294...71,074,110 		JBrowse link
G Tfeb transcription factor EB multiple interactions ISO [Curcumin co-treated with sodium arsenite] promotes the reaction TFEB protein; NFE2L2 protein affects the reaction [[Curcumin co-treated with sodium arsenite] promotes the reaction TFEB protein] CTD PMID:34758851 NCBI chr17:48,047,962...48,103,341
Ensembl chr17:48,047,955...48,103,344 		JBrowse link
G Tfrc transferrin receptor increases expression
multiple interactions		 ISO
EXP		 Curcumin results in increased expression of TFRC mRNA
Curcumin inhibits the reaction [Carbon Tetrachloride results in decreased expression of TFRC protein]		 CTD PMID:17198877 PMID:18340409 PMID:24634837 NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression
decreases activity		 ISO
EXP		 Curcumin inhibits the reaction [TGFB1 protein results in increased expression of RARA mRNA]
[1,2-Dimethylhydrazine co-treated with Curcumin] results in increased expression of TGFB1 mRNA; Curcumin affects the reaction [sodium arsenite results in increased expression of TGFB1 mRNA]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]
Curcumin results in decreased expression of TGFB1 mRNA; Curcumin results in decreased expression of TGFB1 protein
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of TGFB1 protein]]; [Arsenic Trioxide co-treated with Curcumin] inhibits the reaction [Cisplatin results in increased expression of TGFB1 mRNA]; [Zinc binds to Curcumin] which affects the expression of TGFB1 mRNA; Curcumin analog inhibits the reaction [Glucose results in increased expression of TGFB1 mRNA]; Curcumin inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein]; Curcumin inhibits the reaction [Cisplatin results in increased expression of TGFB1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of TGFB1 mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of TGFB1 protein]; Curcumin inhibits the reaction [TGFB1 protein results in decreased expression of PPARG mRNA]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of TGFB1 protein]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in increased expression of TGFB1 protein]]
Curcumin results in decreased activity of TGFB1 protein		 CTD PMID:8940178 PMID:16751071 PMID:16959952 PMID:17434272 PMID:18006644 More... NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I multiple interactions
decreases expression		 ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [Curcumin results in decreased expression of TGFBR1 protein]; Buthionine Sulfoximine inhibits the reaction [Curcumin results in decreased expression of TGFBR1 mRNA]; Buthionine Sulfoximine inhibits the reaction [Curcumin results in decreased expression of TGFBR1 protein]
Curcumin results in decreased expression of TGFBR1 mRNA; Curcumin results in decreased expression of TGFBR1 protein		 CTD PMID:16959952 PMID:17531121 PMID:17602960 NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II multiple interactions
decreases expression		 ISO Buthionine Sulfoximine inhibits the reaction [Curcumin results in decreased expression of TGFBR2 mRNA]; Buthionine Sulfoximine inhibits the reaction [Curcumin results in decreased expression of TGFBR2 protein]
Curcumin results in decreased expression of TGFBR2 mRNA; Curcumin results in decreased expression of TGFBR2 protein		 CTD PMID:16959952 PMID:17602960 NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428 		JBrowse link
G Tgm2 transglutaminase 2, C polypeptide multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGM2 mRNA] CTD PMID:18200517 NCBI chr 2:157,958,325...157,988,312
Ensembl chr 2:157,958,322...157,988,356 		JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO
EXP		 [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased expression of TH protein]; Curcumin inhibits the reaction [sodium arsenite results in decreased expression of TH protein]
Curcumin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein]		 CTD PMID:19631675 PMID:22704994 PMID:27966075 PMID:30463061 PMID:31187328 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865 		JBrowse link
G Thbs1 thrombospondin 1 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of THBS1 mRNA] CTD PMID:18200517 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614 		JBrowse link
G Thy1 thymus cell antigen 1, theta multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of THY1 mRNA] CTD PMID:18200517 NCBI chr 9:43,954,681...43,959,876
Ensembl chr 9:43,954,681...43,959,876 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of TICAM1 mRNA] CTD PMID:23452621 NCBI chr17:56,576,462...56,583,767
Ensembl chr17:56,576,319...56,583,786 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of TICAM2 mRNA] CTD PMID:23452621 NCBI chr18:46,691,298...46,707,600
Ensembl chr18:46,690,358...46,707,600 		JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 multiple interactions
decreases expression		 EXP
ISO		 Curcumin inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA]
Curcumin inhibits the reaction [Cadmium Chloride results in increased export of TIMP1 protein]
Curcumin results in decreased expression of TIMP1 protein		 CTD PMID:17996675 PMID:18200517 PMID:27363783 PMID:29421648 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974 		JBrowse link
G Timp2 tissue inhibitor of metalloproteinase 2 multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Indomethacin results in increased expression of TIMP2 protein]
Curcumin results in decreased expression of TIMP2 protein		 CTD PMID:16934674 PMID:17996675 NCBI chr11:118,191,887...118,246,237
Ensembl chr11:118,191,887...118,246,566 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of and affects the localization of TJP1 protein]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]; Curcumin inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of TJP1 mRNA]; Curcumin inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of TJP1 protein] CTD PMID:26191140 PMID:35817260 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529 		JBrowse link
G Tlr1 toll-like receptor 1 multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of TLR1 mRNA] CTD PMID:23452621 NCBI chr 5:65,082,023...65,090,945
Ensembl chr 5:65,082,022...65,090,906 		JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions ISO Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR2 mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR2 protein]
Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of TLR2 mRNA]		 CTD PMID:22683883 PMID:23452621 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions
decreases expression		 EXP
ISO		 [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TLR4 mRNA]; [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TLR4 protein]; Curcumin inhibits the reaction [[Lipopolysaccharides binds to TLR4 protein] which results in increased activity of IRF3 protein]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TLR4 mRNA]; Curcumin inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TLR4 protein]; Curcumin inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]
Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TLR4 protein]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TLR4 protein]
Curcumin results in decreased expression of TLR4 mRNA; Curcumin results in decreased expression of TLR4 protein		 CTD PMID:16678799 PMID:17965732 PMID:19002562 PMID:22683883 PMID:34719837 More... NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tmt1a thiol methyltransferase 1A1 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of METTL7A mRNA] CTD PMID:18200517 NCBI chr15:100,201,969...100,227,882
Ensembl chr15:100,202,021...100,226,543 		JBrowse link
G Tnc tenascin C multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNC mRNA] CTD PMID:18200517 NCBI chr 4:63,878,022...63,965,554
Ensembl chr 4:63,878,022...63,965,252 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
affects expression
increases expression		 ISO
EXP		 [Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]] which results in increased expression of HMOX1 protein; chromium mesoporphyrin inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; Curcumin inhibits the reaction [[benz(a)anthracene co-treated with TNF protein] results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased phosphorylation of MAPK14 protein]; Curcumin inhibits the reaction [bisphenol A results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [bisphenol A results in increased expression of TNF protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of TNF protein]; Curcumin inhibits the reaction [nickel chloride results in increased expression of TNF protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of TNF protein]; Curcumin inhibits the reaction [TNF protein affects the localization of RELA protein]; Curcumin inhibits the reaction [TNF protein promotes the reaction [Shiga Toxin binds to globotriaosylceramide]]; Curcumin inhibits the reaction [TNF protein results in decreased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [TNF protein results in decreased expression of IL1B mRNA]; Curcumin inhibits the reaction [TNF protein results in decreased expression of IL6 mRNA]; Curcumin inhibits the reaction [TNF protein results in decreased expression of TNF mRNA]; Curcumin inhibits the reaction [TNF protein results in increased acetylation of RELA protein]; Curcumin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Curcumin inhibits the reaction [TNF protein results in increased activity of CHUK protein]; Curcumin inhibits the reaction [TNF protein results in increased activity of IKBKB protein]; Curcumin inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]; Curcumin inhibits the reaction [TNF protein results in increased activity of RELA protein]; Curcumin inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of A4GALT mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of ADAM17 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2A1 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2L1 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2L1 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC2 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC3 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of CCND1 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of CCND1 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of CFLAR mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of GSTP1 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of MMP9 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of MYC mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of TNFRSF1A mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of TNFRSF1A protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of TNFRSF1B mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of TNFRSF1B protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of TRAF1 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of XIAP mRNA]; Curcumin inhibits the reaction [TNF protein results in increased localization of and results in increased activity of RELA protein]; Curcumin inhibits the reaction [TNF protein results in increased localization of RELA protein]; Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]; Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of STAT3 protein]; Dithiothreitol inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]]; Dithiothreitol inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased activity of RELA protein]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased activity of RELA protein]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2 protein]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of BCL2L1 protein]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of CCND1 protein]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of MMP9 protein]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of NOS2 protein]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]]; Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of AKT1 protein]]; MIR125A mRNA inhibits the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of TNF protein]]; SIRT6 protein promotes the reaction [Curcumin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased expression of TNF protein]]
Curcumin results in decreased expression of TNF mRNA; Curcumin results in decreased expression of TNF protein
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; [Sitagliptin Phosphate co-treated with Curcumin] inhibits the reaction [decamethrin results in increased expression of TNF protein]; [Zinc binds to Curcumin] inhibits the reaction [Ethanol results in increased expression of TNF mRNA]; CD40 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of TNF protein]]; Curcumin affects the reaction [Lipopolysaccharides affects the expression of TNF protein]; Curcumin analog inhibits the reaction [Glucose results in increased expression of TNF mRNA]; Curcumin analog inhibits the reaction [Monocrotaline results in increased expression of TNF protein]; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of TNF protein]; Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with Tobacco Smoke Pollution] results in increased expression of TNF protein]; Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased secretion of CXCL2 protein]; Curcumin inhibits the reaction [Acetaminophen results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; Curcumin inhibits the reaction [Colistin results in increased expression of TNF protein]; Curcumin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Curcumin inhibits the reaction [decamethrin results in increased expression of TNF protein]; Curcumin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Curcumin inhibits the reaction [Ethanol results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Fructose results in increased expression of TNF protein]; Curcumin inhibits the reaction [Glucose results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Curcumin inhibits the reaction [sodium arsenite results in increased expression of TNF protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of TNF protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of TNF protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of SELE protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of SELP protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; ICAM1 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of TNF protein]]; pomegranate fruit rind promotes the reaction [Curcumin inhibits the reaction [Thioacetamide results in increased expression of TNF protein]]
Curcumin affects the expression of TNF mRNA; Curcumin affects the expression of TNF protein
Curcumin analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Curcumin inhibits the reaction [butylbenzyl phthalate promotes the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of TNF mRNA]]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Dibutyl Phthalate results in increased expression of TNF protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Curcumin inhibits the reaction [Paraquat results in increased expression of TNF protein]; Curcumin inhibits the reaction [sodium arsenite affects the expression of TNF mRNA]; Curcumin inhibits the reaction [TNF protein results in increased abundance of Dinoprostone]; Curcumin inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]; Curcumin inhibits the reaction [TNF protein results in increased secretion of Dinoprostone]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; NFE2L2 gene mutant form inhibits the reaction [Curcumin results in decreased expression of TNF mRNA]
Curcumin results in increased expression of TNF mRNA		 CTD PMID:14555224 PMID:15489888 PMID:16023083 PMID:16219905 PMID:16584726 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of TNFRSF10A mRNA]; TNFSF10 protein promotes the reaction [Curcumin results in increased expression of TNFRSF10A protein] CTD PMID:18226269 PMID:23452621 NCBI chr14:70,004,921...70,021,860
Ensembl chr14:70,004,921...70,021,860 		JBrowse link
G Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a multiple interactions ISO Curcumin inhibits the reaction [Doxorubicin results in increased expression of TNFRSF12A mRNA] CTD PMID:34047412 NCBI chr17:23,894,419...23,896,423
Ensembl chr17:23,894,419...23,896,442 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of TNFRSF1A mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of TNFRSF1A mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of TNFRSF1A protein] CTD PMID:17666914 PMID:23452621 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b multiple interactions ISO Curcumin inhibits the reaction [TNF protein results in increased expression of TNFRSF1B mRNA]; Curcumin inhibits the reaction [TNF protein results in increased expression of TNFRSF1B protein] CTD PMID:17666914 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440 		JBrowse link
G Tnfrsf21 tumor necrosis factor receptor superfamily, member 21 multiple interactions ISO [arsenic trioxide co-treated with Curcumin] results in increased expression of TNFRSF21 protein CTD PMID:27430728 NCBI chr17:43,327,446...43,400,079
Ensembl chr17:43,327,446...43,400,080 		JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of TNFSF10 mRNA]; TNFSF10 protein promotes the reaction [Curcumin results in decreased activity of RELA protein]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of BCL2 protein]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of BCL2L1 protein]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of CCND1 protein]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of CXCL8 protein]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of MMP2 protein]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of MMP9 protein]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of PLAU protein]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of PTGS2 protein]; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of VEGFA protein]; TNFSF10 protein promotes the reaction [Curcumin results in increased expression of BAK1 protein]; TNFSF10 protein promotes the reaction [Curcumin results in increased expression of BAX protein]; TNFSF10 protein promotes the reaction [Curcumin results in increased expression of CDKN1A protein]; TNFSF10 protein promotes the reaction [Curcumin results in increased expression of CDKN1B protein]; TNFSF10 protein promotes the reaction [Curcumin results in increased expression of TNFRSF10A protein]; TNFSF10 protein promotes the reaction [Curcumin results in increased expression of TNFRSF10B protein]
Curcumin results in decreased expression of TNFSF10 mRNA		 CTD PMID:15713895 PMID:16101141 PMID:18226269 PMID:23452621 NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576 		JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 multiple interactions ISO
EXP		 Curcumin inhibits the reaction [TNFSF11 protein results in increased activity of CHUK protein]; Curcumin inhibits the reaction [TNFSF11 protein results in increased expression of PTGS2 protein]
Curcumin inhibits the reaction [IL1A protein results in increased expression of TNFSF11 protein]		 CTD PMID:15129424 PMID:18719352 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483 		JBrowse link
G Tnfsf12 tumor necrosis factor (ligand) superfamily, member 12 multiple interactions ISO Curcumin inhibits the reaction [Doxorubicin results in increased expression of TNFSF12 protein] CTD PMID:34047412 NCBI chr11:69,577,066...69,586,924
Ensembl chr11:69,577,076...69,586,675 		JBrowse link
G Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 multiple interactions ISO Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of TNFSF14 mRNA] CTD PMID:23452621 NCBI chr17:57,496,437...57,501,182
Ensembl chr17:57,496,492...57,501,177 		JBrowse link
G Tnks tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase decreases expression ISO Curcumin analog results in decreased expression of TNKS mRNA CTD PMID:26409325 NCBI chr 8:35,296,333...35,432,844
Ensembl chr 8:35,293,614...35,432,844 		JBrowse link
G Tnni3 troponin I, cardiac 3 multiple interactions ISO Curcumin inhibits the reaction [Doxorubicin results in increased expression of TNNI3 protein] CTD PMID:29315967 NCBI chr 7:4,521,304...4,526,228
Ensembl chr 7:4,521,304...4,527,228 		JBrowse link
G Top2a topoisomerase (DNA) II alpha multiple interactions
decreases expression		 ISO [Curcumin co-treated with Azacitidine] results in decreased expression of TOP2A mRNA; [sulfinosine co-treated with Curcumin] results in decreased expression of TOP2A mRNA
Curcumin analog results in decreased expression of TOP2A mRNA; Curcumin results in decreased expression of TOP2A mRNA		 CTD PMID:18348204 PMID:18414057 PMID:26409325 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015 		JBrowse link
G Top2b topoisomerase (DNA) II beta multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [Arsenic results in decreased expression of TOP2B mRNA]; Curcumin inhibits the reaction [Arsenic results in decreased expression of TOP2B protein]
Curcumin analog results in decreased expression of TOP2B mRNA		 CTD PMID:21332098 PMID:26409325 NCBI chr14:6,038,976...6,104,585
Ensembl chr14:6,034,301...6,104,584 		JBrowse link
G Tph1 tryptophan hydroxylase 1 multiple interactions ISO [Curcumin co-treated with Chitosan analog] inhibits the reaction [Arsenic results in decreased expression of TPH1 protein] CTD PMID:22704994 NCBI chr 7:46,294,065...46,321,961
Ensembl chr 7:46,294,065...46,321,961 		JBrowse link
G Tradd TNFRSF1A-associated via death domain decreases expression ISO Curcumin results in decreased expression of TRADD mRNA CTD PMID:15713895 NCBI chr 8:105,985,207...105,991,226
Ensembl chr 8:105,984,918...105,991,241 		JBrowse link
G Traf1 TNF receptor-associated factor 1 multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [TNF protein results in increased expression of TRAF1 mRNA]
Curcumin results in decreased expression of TRAF1 protein		 CTD PMID:16023083 PMID:16219905 PMID:19372569 NCBI chr 2:34,831,762...34,851,784
Ensembl chr 2:34,831,762...34,851,784 		JBrowse link
G Traf2 TNF receptor-associated factor 2 increases expression ISO Curcumin results in increased expression of TRAF2 mRNA CTD PMID:16101141 NCBI chr 2:25,407,994...25,436,952
Ensembl chr 2:25,407,994...25,436,952 		JBrowse link
G Traf3 TNF receptor-associated factor 3 increases expression ISO Curcumin results in increased expression of TRAF3 mRNA CTD PMID:16101141 NCBI chr12:111,132,799...111,233,589
Ensembl chr12:111,132,804...111,233,587 		JBrowse link
G Traf6 TNF receptor-associated factor 6 increases expression
multiple interactions		 ISO Curcumin results in increased expression of TRAF6 mRNA
Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TRAF6 mRNA]		 CTD PMID:16101141 PMID:34719837 NCBI chr 2:101,508,765...101,532,013
Ensembl chr 2:101,508,774...101,532,014 		JBrowse link
G Trdmt1 tRNA aspartic acid methyltransferase 1 increases expression ISO Curcumin results in increased expression of DNMT2 CTD PMID:25644192 NCBI chr 2:13,509,690...13,549,475
Ensembl chr 2:13,513,825...13,549,479 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 decreases expression ISO Curcumin results in decreased expression of TREM1 mRNA CTD PMID:17198877 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952 		JBrowse link
G Trf transferrin increases expression ISO Curcumin results in increased expression of TF mRNA CTD PMID:15713895 NCBI chr 9:103,086,075...103,107,485
Ensembl chr 9:103,081,200...103,107,643 		JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Curcumin results in increased expression of TRIB3 mRNA CTD PMID:18719366 NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952 		JBrowse link
G Trim15 tripartite motif-containing 15 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TRIM15 mRNA] CTD PMID:18200517 NCBI chr17:37,171,582...37,179,066
Ensembl chr17:37,171,583...37,178,102 		JBrowse link
G Trim16 tripartite motif-containing 16 increases expression ISO Curcumin results in increased expression of TRIM16 mRNA CTD PMID:17999991 NCBI chr11:62,711,034...62,733,774
Ensembl chr11:62,711,057...62,741,634 		JBrowse link
G Trp53 transformation related protein 53 multiple interactions
decreases expression
increases expression
increases phosphorylation
increases acetylation
affects expression
affects localization		 ISO
EXP		 [Arsenic Trioxide co-treated with Curcumin] results in increased expression of TP53 protein; [Curcumin co-treated with Arsenic Trioxide] results in increased expression of TP53 protein; [Curcumin co-treated with Metribolone] results in increased phosphorylation of TP53 protein; [piperine co-treated with Curcumin] results in decreased expression of TP53 protein; [Vitamin E co-treated with Curcumin] results in decreased expression of TP53 protein; Curcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of and results in increased activity of TP53 protein]; Curcumin inhibits the reaction [bisphenol A results in decreased expression of TP53 protein]; Curcumin inhibits the reaction [bisphenol A results in increased expression of TP53 protein]; dorsomorphin inhibits the reaction [Curcumin results in increased phosphorylation of TP53 protein]; SB 203580 inhibits the reaction [Curcumin results in increased phosphorylation of TP53 protein]
Curcumin analog results in decreased expression of TP53 mRNA; Curcumin results in decreased expression of TP53 mRNA; Curcumin results in decreased expression of TP53 protein
Curcumin results in increased expression of TRP53 mRNA
[Curcumin co-treated with Quercetin] inhibits the reaction [Benzo(a)pyrene results in decreased acetylation of TRP53 protein]; [Curcumin co-treated with Quercetin] inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of TRP53 protein]; Curcumin affects the reaction [KRAS protein affects the localization of TRP53 protein]; Curcumin inhibits the reaction [Benzo(a)pyrene results in decreased acetylation of TRP53 protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of TRP53 protein]
[Curcumin results in increased expression of SERPINB5] which results in increased expression of TP53 protein; Curcumin results in increased expression of TP53; Curcumin results in increased expression of TP53 protein
[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]]; carboxymethyl-chitosan analog promotes the reaction [Curcumin inhibits the reaction [AGT protein modified form results in increased acetylation of TP53 protein]]; Curcumin inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in increased expression of TP53 mRNA]; Curcumin inhibits the reaction [AGT protein modified form promotes the reaction [TP53 protein binds to EP300 protein]]; Curcumin inhibits the reaction [AGT protein modified form results in increased expression of and results in increased phosphorylation of and results in increased acetylation of TP53 protein]; Curcumin inhibits the reaction [Cyclophosphamide results in increased mutagenesis of TP53 exon]; Curcumin inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]; Curcumin inhibits the reaction [TP53 protein binds to EP300 protein]; Curcumin results in decreased expression of and results in decreased acetylation of TP53 protein
Curcumin results in increased acetylation of TP53 protein
Curcumin affects the expression of TP53 protein; Curcumin analog affects the expression of TP53 mRNA; Curcumin analog affects the expression of TP53 protein
Curcumin affects the localization of TP53 protein		 CTD PMID:17041101 PMID:17332930 PMID:19020741 PMID:19227835 PMID:19944674 More... NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 multiple interactions ISO [Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of TRPV6 mRNA CTD PMID:20153625 NCBI chr 6:41,597,553...41,613,339
Ensembl chr 6:41,597,558...41,613,339 		JBrowse link
G Tsc2 TSC complex subunit 2 decreases phosphorylation ISO Curcumin results in decreased phosphorylation of TSC2 protein CTD PMID:18790744 NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604 		JBrowse link
G Tubb3 tubulin, beta 3 class III multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [bisphenol A results in decreased expression of TUBB3 mRNA]
Curcumin results in increased expression of TUBB3 mRNA		 CTD PMID:25963729 NCBI chr 8:124,138,292...124,148,754
Ensembl chr 8:124,138,163...124,148,754 		JBrowse link
G Txnip thioredoxin interacting protein multiple interactions EXP Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of TXNIP mRNA] CTD PMID:35063475 NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression
increases oxidation		 ISO
EXP		 Curcumin analog results in increased expression of TXNRD1 mRNA; Curcumin results in increased expression of TXNRD1 mRNA
Curcumin results in increased oxidation of TXNRD1 protein		 CTD PMID:17198877 PMID:18299980 PMID:21782934 PMID:26409325 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546 		JBrowse link
G Tymp thymidine phosphorylase decreases expression
multiple interactions		 ISO Curcumin results in decreased expression of TYMP mRNA; Curcumin results in decreased expression of TYMP protein
[Curcumin results in decreased expression of TYMP protein] which results in increased susceptibility to Cisplatin		 CTD PMID:21493726 NCBI chr15:89,255,834...89,261,282
Ensembl chr15:89,256,134...89,261,242 		JBrowse link
G Tyrobp TYRO protein tyrosine kinase binding protein multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TYROBP mRNA] CTD PMID:18200517 NCBI chr 7:30,113,207...30,117,007
Ensembl chr 7:30,113,185...30,117,010 		JBrowse link
G Uba7 ubiquitin-like modifier activating enzyme 7 affects expression
multiple interactions		 ISO Curcumin affects the expression of UBA7 mRNA; Curcumin affects the expression of UBA7 protein
Curcumin affects the reaction [Acetylcysteine results in increased expression of UBA7 protein]; Curcumin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of UBA7 protein]		 CTD PMID:25649257 NCBI chr 9:107,852,766...107,861,255
Ensembl chr 9:107,852,704...107,861,259 		JBrowse link
G Ubc ubiquitin C increases expression ISO Curcumin results in increased expression of UBC mRNA CTD PMID:16101141 NCBI chr 5:125,463,029...125,467,081
Ensembl chr 5:125,463,029...125,467,266 		JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression ISO Curcumin results in decreased expression of UBE2C mRNA CTD PMID:22258452 NCBI chr 2:164,611,849...164,614,822
Ensembl chr 2:164,611,818...164,620,742 		JBrowse link
G Ucp1 uncoupling protein 1 (mitochondrial, proton carrier) affects expression EXP Curcumin affects the expression of UCP1 mRNA CTD PMID:27208389 NCBI chr 8:84,016,977...84,025,085
Ensembl chr 8:84,016,981...84,025,081 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 increases expression
multiple interactions
increases glucuronidation		 ISO
EXP		 Curcumin results in increased expression of UGT1A1 mRNA
Curcumin analog results in increased expression of UGT1A1 mRNA; Curcumin analog results in increased expression of UGT1A1 protein
Curcumin promotes the reaction [Aflatoxin B1 results in increased activity of UGT1A1 protein]
UGT1A1 protein results in increased glucuronidation of Curcumin		 CTD PMID:14557274 PMID:16819192 PMID:20015472 PMID:26991801 PMID:29228771 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 increases glucuronidation ISO UGT1A10 protein results in increased glucuronidation of Curcumin CTD PMID:14557274 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726 		JBrowse link
G Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B increases expression ISO Curcumin results in increased expression of UGT1A6 mRNA CTD PMID:16819192 NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of Curcumin CTD PMID:14557274 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719 		JBrowse link
G Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of UGT2B5 mRNA] CTD PMID:18200517 NCBI chr 5:87,272,805...87,288,199
Ensembl chr 5:87,272,819...87,288,177 		JBrowse link
G Utp14a UTP14A small subunit processome component increases expression ISO Curcumin results in increased expression of UTP14A mRNA CTD PMID:17198877 NCBI chr  X:47,345,811...47,371,326
Ensembl chr  X:47,345,739...47,371,330 		JBrowse link
G Vasp vasodilator-stimulated phosphoprotein increases expression ISO Curcumin results in increased expression of VASP mRNA CTD PMID:17198877 NCBI chr 7:18,990,854...19,005,779
Ensembl chr 7:18,990,854...19,005,742 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 affects expression
multiple interactions		 EXP
ISO		 Curcumin affects the expression of VCAM1 mRNA
Curcumin inhibits the reaction [Particulate Matter results in increased expression of VCAM1 protein]; Curcumin inhibits the reaction [titanium dioxide results in increased expression of VCAM1 protein]
Curcumin analog inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]
Curcumin analog inhibits the reaction [Copper Sulfate results in increased expression of VCAM1 protein]; Curcumin analog inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]; Curcumin inhibits the reaction [Copper Sulfate results in increased expression of VCAM1 protein]; Curcumin inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]		 CTD PMID:18752423 PMID:28700904 PMID:29244817 PMID:30431687 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337 		JBrowse link
G Vcan versican multiple interactions EXP Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAN mRNA] CTD PMID:18200517 NCBI chr13:89,803,429...89,891,146
Ensembl chr13:89,803,431...89,890,628 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO Curcumin promotes the reaction [VDAC1 protein binds to VDAC1 protein] CTD PMID:28343033 NCBI chr11:52,251,905...52,280,224
Ensembl chr11:52,251,687...52,280,224 		JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor multiple interactions ISO [Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of CDKN1A mRNA; [Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of CYP24A1 mRNA; [Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of CYP3A4 mRNA; [Curcumin binds to and results in increased activity of VDR protein] which results in increased expression of TRPV6 mRNA; Curcumin binds to and results in increased activity of VDR protein; Curcumin inhibits the reaction [1,25-dihydroxy-26,27-dimethylcholecalciferol binds to VDR protein]; Curcumin promotes the reaction [VDR protein binds to NCOA1 protein]; Curcumin promotes the reaction [VDR protein binds to RXRA protein] CTD PMID:20153625 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511 		JBrowse link
G Vegfa vascular endothelial growth factor A affects expression
decreases expression
multiple interactions		 ISO
EXP		 Curcumin affects the expression of VEGFA mRNA
Curcumin results in decreased expression of VEGFA mRNA; Curcumin results in decreased expression of VEGFA protein
Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of VEGFA mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]
[Curcumin co-treated with Gemcitabine] results in decreased expression of VEGFA protein; Curcumin inhibits the reaction [Dietary Fats results in increased expression of VEGFA mRNA]
[bisdemethoxycurcumin co-treated with Curcumin co-treated with demethoxycurcumin] inhibits the reaction [VEGF protein results in increased phosphorylation of AKT1 protein]; [bisdemethoxycurcumin co-treated with Curcumin co-treated with demethoxycurcumin] inhibits the reaction [VEGF protein results in increased phosphorylation of KDR protein]; [bisdemethoxycurcumin co-treated with Curcumin co-treated with demethoxycurcumin] inhibits the reaction [VEGF protein results in increased phosphorylation of MAPK1 protein]; [bisdemethoxycurcumin co-treated with Curcumin co-treated with demethoxycurcumin] inhibits the reaction [VEGF protein results in increased phosphorylation of MAPK3 protein]; [Curcumin analog co-treated with Sirolimus] inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; [Curcumin analog co-treated with terpestacin] inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; [Curcumin analog co-treated with Vorinostat] inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; [Curcumin co-treated with Bortezomib] results in decreased expression of VEGFA protein; Curcumin analog inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]; Curcumin inhibits the reaction [IL18 protein results in increased expression of VEGFA mRNA]; Curcumin inhibits the reaction [IL18 protein results in increased expression of VEGFA protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased secretion of VEGFA protein]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of VEGFA protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA]; Curcumin inhibits the reaction [VEGF protein results in increased phosphorylation of KDR protein]; Curcumin inhibits the reaction [VEGF protein results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [VEGF protein results in increased phosphorylation of MAPK3 protein]; Curcumin inhibits the reaction [VEGFA protein results in increased expression of and results in increased activity of MMP2 protein]; Curcumin inhibits the reaction [VEGFA protein results in increased expression of PTGS2 mRNA]; Curcumin inhibits the reaction [VEGFA protein results in increased expression of PTGS2 protein]; Curcumin results in decreased expression of and results in decreased secretion of VEGFA protein; TNFSF10 protein promotes the reaction [Curcumin results in decreased expression of VEGFA protein]		 CTD PMID:16219905 PMID:16243823 PMID:16368150 PMID:17440100 PMID:17662242 More... NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor multiple interactions ISO VHL protein promotes the reaction [Curcumin results in decreased expression of HIF1A protein] CTD PMID:18682687 NCBI chr 6:113,600,955...113,608,595
Ensembl chr 6:113,600,920...113,608,594 		JBrowse link
G Vim vimentin multiple interactions ISO
EXP		 Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VIM protein]
Curcumin inhibits the reaction [Tobacco Smoke Pollution results in increased expression of VIM mRNA]; Curcumin inhibits the reaction [Tobacco Smoke Pollution results in increased expression of VIM protein]		 CTD PMID:25656647 PMID:26191140 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637 		JBrowse link
G Vip vasoactive intestinal polypeptide multiple interactions ISO Curcumin inhibits the reaction [VIP protein results in increased activity of MMP2 protein]; Curcumin inhibits the reaction [VIP protein results in increased activity of MMP9 protein]; Curcumin inhibits the reaction [VIP protein results in increased expression of CCND1 protein]
Curcumin inhibits the reaction [VIP protein results in increased expression of PTGS2 protein]		 CTD PMID:17434257 PMID:19189304 NCBI chr10:5,589,131...5,597,617
Ensembl chr10:5,589,218...5,597,617 		JBrowse link
G Vwf Von Willebrand factor multiple interactions ISO Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of VWF mRNA]; Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of VWF protein] CTD PMID:23845850 NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642 		JBrowse link
G Wasl WASP like actin nucleation promoting factor increases expression EXP Curcumin results in increased expression of WASL mRNA CTD PMID:18200517 NCBI chr 6:24,613,809...24,665,185
Ensembl chr 6:24,613,804...24,665,008 		JBrowse link
G Wif1 Wnt inhibitory factor 1 multiple interactions
decreases expression		 ISO Curcumin inhibits the reaction [bisphenol A results in increased expression of WIF1 protein]
Curcumin results in decreased expression of WIF1 protein		 CTD PMID:25963729 NCBI chr10:120,869,909...120,936,547
Ensembl chr10:120,869,865...120,936,555 		JBrowse link
G Wnt1 wingless-type MMTV integration site family, member 1 increases expression
multiple interactions		 ISO Curcumin results in increased expression of WNT1 mRNA
Curcumin inhibits the reaction [bisphenol A results in decreased expression of WNT1 mRNA]		 CTD PMID:25963729 NCBI chr15:98,687,738...98,691,711
Ensembl chr15:98,687,738...98,691,718 		JBrowse link
G Wnt3 wingless-type MMTV integration site family, member 3 multiple interactions
increases expression		 ISO Curcumin inhibits the reaction [bisphenol A results in decreased expression of WNT3 mRNA]; Curcumin inhibits the reaction [bisphenol A results in decreased expression of WNT3 protein]
Curcumin results in increased expression of WNT3 mRNA; Curcumin results in increased expression of WNT3 protein		 CTD PMID:25963729 NCBI chr11:103,665,000...103,708,854
Ensembl chr11:103,664,976...103,708,783 		JBrowse link
G Wt1 WT1 transcription factor decreases expression ISO Curcumin results in decreased expression of WT1 mRNA; Curcumin results in decreased expression of WT1 protein CTD PMID:18034345 PMID:19196508 NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961 		JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 decreases stability
multiple interactions		 ISO Curcumin results in decreased stability of WWTR1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of WWTR1 protein]; Curcumin results in decreased expression of and affects the localization of WWTR1 protein; Curcumin results in increased phosphorylation of and results in decreased stability of WWTR1 protein; WWTR1 protein inhibits the reaction [Curcumin results in decreased expression of EPCAM mRNA]; WWTR1 protein inhibits the reaction [Curcumin results in decreased expression of EPCAM protein]; WWTR1 protein inhibits the reaction [Curcumin results in decreased expression of POU5F1 mRNA]; WWTR1 protein inhibits the reaction [Curcumin results in decreased expression of POU5F1 protein]; WWTR1 protein inhibits the reaction [Curcumin results in decreased expression of PROM1 mRNA]; WWTR1 protein inhibits the reaction [Curcumin results in decreased expression of PROM1 protein]; WWTR1 protein inhibits the reaction [Curcumin results in increased susceptibility to Cisplatin]		 CTD PMID:33539684 NCBI chr 3:57,363,065...57,483,331
Ensembl chr 3:57,363,070...57,483,331 		JBrowse link
G Xaf1 XIAP associated factor 1 increases expression ISO Curcumin results in increased expression of XAF1 mRNA; Curcumin results in increased expression of XAF1 protein CTD PMID:21594647 NCBI chr11:72,192,229...72,204,560
Ensembl chr11:72,192,455...72,204,559 		JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO Curcumin results in increased expression of XBP1 mRNA CTD PMID:29723631 NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893 		JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO Curcumin inhibits the reaction [Indomethacin results in increased activity of XDH protein] CTD PMID:17351913 NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191 		JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions
decreases expression		 ISO [arsenic trioxide co-treated with Curcumin] results in decreased expression of XIAP protein; [Curcumin co-treated with Doxorubicin] affects the expression of XIAP mRNA; arsenic trioxide promotes the reaction [Curcumin results in decreased expression of XIAP protein]; Curcumin inhibits the reaction [Nicotine results in increased expression of XIAP protein]; Curcumin inhibits the reaction [Paclitaxel results in increased expression of XIAP protein]; Curcumin inhibits the reaction [TNF protein results in increased expression of XIAP mRNA]; Curcumin promotes the reaction [lonidamine results in decreased expression of XIAP protein]; lonidamine promotes the reaction [Curcumin results in decreased expression of XIAP protein]
Curcumin analog results in decreased expression of XIAP mRNA; Curcumin results in decreased expression of XIAP mRNA; Curcumin results in decreased expression of XIAP protein		 CTD PMID:15911101 PMID:16023083 PMID:16173963 PMID:16219905 PMID:16243823 More... NCBI chr  X:41,148,483...41,198,541
Ensembl chr  X:41,148,556...41,198,533 		JBrowse link
G Xpo1 exportin 1 multiple interactions EXP Curcumin inhibits the reaction [KRAS protein results in decreased expression of XPO1 protein] CTD PMID:21519798 NCBI chr11:23,205,768...23,248,250
Ensembl chr11:23,206,055...23,248,249 		JBrowse link
G Xrcc1 X-ray repair complementing defective repair in Chinese hamster cells 1 multiple interactions ISO Curcumin inhibits the reaction [Arsenic results in decreased expression of XRCC1 mRNA]; Curcumin inhibits the reaction [Arsenic results in decreased expression of XRCC1 protein] CTD PMID:21332098 NCBI chr 7:24,246,124...24,272,863
Ensembl chr 7:24,245,714...24,272,865 		JBrowse link
G Xrcc4 X-ray repair complementing defective repair in Chinese hamster cells 4 multiple interactions ISO Curcumin inhibits the reaction [Arsenic results in decreased expression of XRCC4 mRNA]; Curcumin inhibits the reaction [Arsenic results in decreased expression of XRCC4 protein] CTD PMID:21332098 NCBI chr13:89,997,033...90,237,727
Ensembl chr13:89,922,146...90,237,727 		JBrowse link
G Xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 decreases expression ISO Curcumin results in decreased expression of XRCC5 mRNA CTD PMID:17596214 NCBI chr 1:72,346,576...72,434,112
Ensembl chr 1:72,346,586...72,434,111 		JBrowse link
G Xrcc6 X-ray repair complementing defective repair in Chinese hamster cells 6 decreases expression ISO Curcumin results in decreased expression of XRCC6 mRNA CTD PMID:17596214 NCBI chr15:81,868,805...81,924,286
Ensembl chr15:81,872,036...81,924,286 		JBrowse link
G Ypel3 yippee like 3 decreases expression ISO Curcumin results in decreased expression of YPEL3 mRNA CTD PMID:17198877 NCBI chr 7:126,376,135...126,379,682
Ensembl chr 7:126,376,127...126,379,686 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide decreases expression ISO Curcumin results in decreased expression of YWHAE mRNA; Curcumin results in decreased expression of YWHAE protein CTD PMID:19294764 NCBI chr11:75,620,121...75,656,667
Ensembl chr11:75,623,695...75,656,671 		JBrowse link
G Zfhx3 zinc finger homeobox 3 decreases expression ISO Curcumin results in decreased expression of ZFHX3 mRNA CTD PMID:17198877 NCBI chr 8:109,005,975...109,688,272
Ensembl chr 8:108,669,276...109,688,262 		JBrowse link
G Zfp287 zinc finger protein 287 increases expression ISO Curcumin results in increased expression of ZNF287 mRNA CTD PMID:18421014 NCBI chr11:62,583,270...62,622,749
Ensembl chr11:62,591,182...62,622,731 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 decreases expression ISO Curcumin results in decreased expression of ZFP36L1 mRNA CTD PMID:15713895 NCBI chr12:80,154,534...80,159,787
Ensembl chr12:80,154,528...80,159,787 		JBrowse link
tetrahydrocurcumin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahcy S-adenosylhomocysteine hydrolase affects expression EXP Tetrahydrocurcumin affects expression of protein and mRNA in ischemia/reperfusion CBS+/- mice RGD PMID:22212488 RGD:41410880 NCBI chr 2:154,901,230...154,916,417
Ensembl chr 2:154,901,230...154,916,417 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO tetrahydrocurcumin inhibits the reaction [APP protein binds to APP protein] CTD PMID:19715544 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654 		JBrowse link
G Cat catalase multiple interactions
affects expression 		ISO
EXP		 tetrahydrocurcumin inhibits the reaction [Chloroquine results in decreased activity of CAT protein]; tetrahydrocurcumin inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; tetrahydrocurcumin inhibits the reaction [Vincristine results in decreased expression of CAT protein]
tetrahydrocurcumin inhibits the reaction [Acetaminophen results in decreased expression of CAT protein]
Tetrahydrocurcumin affects expression of protein and mRNA in ischemia/reperfusion CBS+/- mice		 CTD
RGD		 PMID:17076682 PMID:25869292 PMID:26102012 PMID:30423402 PMID:22212488 RGD:41410880 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA] CTD PMID:26102010 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions EXP tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1B1 mRNA]; tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1B1 protein] CTD PMID:26102010 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 decreases expression EXP tetrahydrocurcumin results in decreased expression of CYP2B10 mRNA CTD PMID:26102010 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9 decreases expression EXP tetrahydrocurcumin results in decreased expression of CYP2B9 mRNA CTD PMID:26102010 NCBI chr 7:25,872,775...25,910,086
Ensembl chr 7:25,872,836...25,910,086 		JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 multiple interactions EXP tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP2C29 mRNA]; tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP2C29 protein] CTD PMID:26102010 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP tetrahydrocurcumin inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA]; tetrahydrocurcumin inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein] CTD PMID:30423402 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 multiple interactions
increases expression		 EXP tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP3A11 mRNA]
tetrahydrocurcumin results in increased expression of CYP3A11 protein		 CTD PMID:26102010 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions EXP tetrahydrocurcumin inhibits the reaction [Acetaminophen results in increased expression of GPT protein] CTD PMID:30423402 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions ISO [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein] CTD PMID:20696151 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444 		JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions ISO [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein] CTD PMID:20696151 NCBI chr 8:106,666,183...106,670,034
Ensembl chr 8:106,666,183...106,670,014 		JBrowse link
G Lpl lipoprotein lipase multiple interactions ISO [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein] CTD PMID:20696151 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP tetrahydrocurcumin inhibits the reaction [Cadmium Chloride results in increased expression of MMP2 protein] CTD PMID:25502771 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
affects expression 		EXP tetrahydrocurcumin inhibits the reaction [Cadmium Chloride results in increased expression of MMP9 protein]
Tetrahydrocurcumin affects expression of protein and mRNA in ischemia/reperfusion CBS+/- mice		 CTD
RGD		 PMID:25502771 PMID:22212488 RGD:41410880 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase affects expression EXP Tetrahydrocurcumin affects expression of protein and mRNA in ischemia/reperfusion CBS+/- mice RGD PMID:22212488 RGD:41410880 NCBI chr 4:148,123,534...148,144,019
Ensembl chr 4:148,123,534...148,144,008 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 affects expression EXP Tetrahydrocurcumin affects expression of protein and mRNA in ischemia/reperfusion CBS+/- mice RGD PMID:22212488 RGD:41410880 NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP tetrahydrocurcumin inhibits the reaction [Cadmium Chloride results in increased expression of NOS2 protein] CTD PMID:25502771 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell multiple interactions EXP tetrahydrocurcumin inhibits the reaction [Cadmium Chloride results in decreased expression of NOS3 protein] CTD PMID:25502771 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression		 EXP tetrahydrocurcumin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
tetrahydrocurcumin results in decreased expression of PTGS2 mRNA		 CTD PMID:18507010 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO tetrahydrocurcumin inhibits the reaction [Vincristine results in increased expression of TNF protein] CTD PMID:26102012 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      chemical role 21407
        antioxidant 16394
          ferulic acid 992
            (+)-DCA-CC 0
            (+)-DCA-CL 0
            (-)-DCA-CC 0
            (-)-DCA-CL 0
            (2E)-3-(4-\{[1-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
            (2E)-3-(4-\{[3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
            (2E)-3-[4-(\{1,3-dihydroxy-1-[3-methoxy-4-(sulfooxy)phenyl]propan-2-yl\}oxy)-3-methoxyphenyl]prop-2-enoic acid 0
            (2R,3R)-trans-fertaric acid 0
            (2R,3S)-glycosmisic acid 0
            (2S,3R)-glycosmisic acid 0
            (2S,3S)-trans-fertaric acid 0
            (R)-N-trans-feruloyloctopamine 0
            1-O-feruloyl-beta-D-glucose 0
            1-caffeoyl-5-feruloylquinic acid 0
            1-feruloyl-sn-glycerol 0
            16-feruloyloxypalmitic acid 0
            2''-O-(6-feruloylglucosyl)isovitexin 0
            3-O-feruloyl-D-quinic acid 0
            3-O-feruloylcycloartenol 0
            4-O-beta-D-glucosyl-trans-ferulic acid 0
            4-O-feruloyl-D-quinic acid 0
            7-O-(6-feruoylglucosyl)isoorientin 0
            8,5'-diferulic acid 0
            Cuscuta propenamide 2 0
            Diferulic acid 0
            N(1),N(5)-dihydroxyferuloyl-N(10)-sinapoyl spermidine 0
            N-feruloylserotonin 0
            N-trans-feruloyl-4'-O-methyldopamine 0
            O-acetylferulic acid 0
            avenanthramide B 0
            curcumin + 943
            ferulic acid 4-sulfate 0
            feruloyl-CoA + 0
            feruloylagmatine + 0
            feruloylglycoside 0
            glycosmisic acid + 0
            isovitexin 7-O-[feruloyl]-glucoside 0
            methyl 4-acetoxy-3-methoxycinnamate 0
            trans-methylferulate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      carbon group element atom 21904
                        carbon atom 21859
                          organic molecular entity 21830
                            heteroorganic entity 21482
                              organochalcogen compound 20966
                                organooxygen compound 20806
                                  carbon oxoacid 19593
                                    carboxylic acid 19589
                                      monocarboxylic acid 18952
                                        alpha,beta-unsaturated monocarboxylic acid 13632
                                          cinnamic acids 2515
                                            hydroxycinnamic acid 1365
                                              monohydroxycinnamic acid 1029
                                                ferulic acids 991
                                                  ferulic acid 992
                                                    (+)-DCA-CC 0
                                                    (+)-DCA-CL 0
                                                    (-)-DCA-CC 0
                                                    (-)-DCA-CL 0
                                                    (2E)-3-(4-\{[1-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
                                                    (2E)-3-(4-\{[3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-(sulfooxy)propan-2-yl]oxy\}-3-methoxyphenyl)prop-2-enoic acid 0
                                                    (2E)-3-[4-(\{1,3-dihydroxy-1-[3-methoxy-4-(sulfooxy)phenyl]propan-2-yl\}oxy)-3-methoxyphenyl]prop-2-enoic acid 0
                                                    (2R,3R)-trans-fertaric acid 0
                                                    (2R,3S)-glycosmisic acid 0
                                                    (2S,3R)-glycosmisic acid 0
                                                    (2S,3S)-trans-fertaric acid 0
                                                    (R)-N-trans-feruloyloctopamine 0
                                                    1-O-feruloyl-beta-D-glucose 0
                                                    1-caffeoyl-5-feruloylquinic acid 0
                                                    1-feruloyl-sn-glycerol 0
                                                    16-feruloyloxypalmitic acid 0
                                                    2''-O-(6-feruloylglucosyl)isovitexin 0
                                                    3-O-feruloyl-D-quinic acid 0
                                                    3-O-feruloylcycloartenol 0
                                                    4-O-beta-D-glucosyl-trans-ferulic acid 0
                                                    4-O-feruloyl-D-quinic acid 0
                                                    7-O-(6-feruoylglucosyl)isoorientin 0
                                                    8,5'-diferulic acid 0
                                                    Cuscuta propenamide 2 0
                                                    Diferulic acid 0
                                                    N(1),N(5)-dihydroxyferuloyl-N(10)-sinapoyl spermidine 0
                                                    N-feruloylserotonin 0
                                                    N-trans-feruloyl-4'-O-methyldopamine 0
                                                    O-acetylferulic acid 0
                                                    avenanthramide B 0
                                                    curcumin + 943
                                                    ferulic acid 4-sulfate 0
                                                    feruloyl-CoA + 0
                                                    feruloylagmatine + 0
                                                    feruloylglycoside 0
                                                    glycosmisic acid + 0
                                                    isovitexin 7-O-[feruloyl]-glucoside 0
                                                    methyl 4-acetoxy-3-methoxycinnamate 0
                                                    trans-methylferulate 0
paths to the root