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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3-Methoxynobiletin
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Accession:CHEBI:176100 term browser browse the term
Synonyms:exact_synonym: 2-(3,4-dimethoxyphenyl)-3,5,6,7,8-pentamethoxychromen-4-one
 related_synonym: Formula=C22H24O9;   InChI=1S/C22H24O9/c1-24-12-9-8-11(10-13(12)25-2)16-19(27-4)15(23)14-17(26-3)20(28-5)22(30-7)21(29-6)18(14)31-16/h8-10H,1-7H3;   InChIKey=SSXJHQZOHUYEGD-UHFFFAOYSA-N;   SMILES=O1C2=C(C(OC)=C(OC)C(OC)=C2OC)C(=O)C(OC)=C1C3=CC(OC)=C(OC)C=C3
 xref: CAS:1178-24-1;   Chemspider:132996;   HMDB:HMDB0037689;   LIPID_MAPS_instance:LMPK12113345
 xref_mesh: MESH:C059294


show annotations for term's descendants           Sort by:
3-Methoxynobiletin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor increases expression
multiple interactions		 EXP 3,3',4',5,6,7,8-heptamethoxyflavone results in increased expression of BDNF protein
U 0126 inhibits the reaction [3,3',4',5,6,7,8-heptamethoxyflavone results in increased expression of BDNF protein]		 CTD PMID:31195342 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions		 EXP 3,3',4',5,6,7,8-heptamethoxyflavone results in increased phosphorylation of CREB1 protein
U 0126 inhibits the reaction [3,3',4',5,6,7,8-heptamethoxyflavone results in increased phosphorylation of CREB1 protein]		 CTD PMID:31195342 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects phosphorylation ISO 3,3',4',5,6,7,8-heptamethoxyflavone affects the phosphorylation of FOS protein CTD PMID:29470423 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit affects phosphorylation ISO 3,3',4',5,6,7,8-heptamethoxyflavone affects the phosphorylation of JUN protein CTD PMID:29470423 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
affects phosphorylation		 EXP
ISO		 U 0126 inhibits the reaction [3,3',4',5,6,7,8-heptamethoxyflavone results in increased phosphorylation of MAPK1 protein]
3,3',4',5,6,7,8-heptamethoxyflavone affects the phosphorylation of MAPK1 protein		 CTD PMID:29470423 PMID:31195342 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects phosphorylation ISO 3,3',4',5,6,7,8-heptamethoxyflavone affects the phosphorylation of MAPK3 protein CTD PMID:29470423 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 affects phosphorylation ISO 3,3',4',5,6,7,8-heptamethoxyflavone affects the phosphorylation of MAPK8 protein CTD PMID:29470423 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mmp1 matrix metallopeptidase 1 affects expression ISO 3,3',4',5,6,7,8-heptamethoxyflavone affects the expression of MMP1 protein CTD PMID:29470423 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Pde4a phosphodiesterase 4A decreases activity EXP 3,3',4',5,6,7,8-heptamethoxyflavone results in decreased activity of PDE4A protein CTD PMID:31195342 NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:19,703,290...19,751,961 		JBrowse link
G Smad3 SMAD family member 3 affects phosphorylation ISO 3,3',4',5,6,7,8-heptamethoxyflavone affects the phosphorylation of SMAD3 protein CTD PMID:29470423 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad7 SMAD family member 7 affects phosphorylation ISO 3,3',4',5,6,7,8-heptamethoxyflavone affects the phosphorylation of SMAD7 protein CTD PMID:29470423 NCBI chr18:71,263,508...71,291,849
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
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  CHEBI ontology 19904
    chemical entity 19902
      atom 19902
        nonmetal atom 19825
          carbon atom 19776
            organic molecular entity 19776
              flavonoids 11635
                3-Methoxynobiletin 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19904
    subatomic particle 19902
      composite particle 19902
        hadron 19902
          baryon 19902
            nucleon 19902
              atomic nucleus 19902
                atom 19902
                  main group element atom 19841
                    p-block element atom 19841
                      carbon group element atom 19779
                        carbon atom 19776
                          organic molecular entity 19776
                            heteroorganic entity 19540
                              organochalcogen compound 19301
                                organooxygen compound 19219
                                  ether 17338
                                    3-Methoxynobiletin 11
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