Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:inosine
go back to main search page
Accession:CHEBI:17596 term browser browse the term
Definition:A purine nucleoside in which hypoxanthine is attached to ribofuranose via a beta-N(9)-glycosidic bond.
Synonyms:exact_synonym: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-hydroxy-9H-purin-9-yl)tetrahydrofuran-3,4-diol
 related_synonym: 9-beta-D-ribofuranosyl-9H-purin-6-ol;   9-beta-D-ribofuranosylhypoxanthine;   Formula=C10H12N4O5;   InChI=1S/C10H12N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,10,15-17H,1H2,(H,11,12,18)/t4-,6-,7-,10-/m1/s1;   InChIKey=UGQMRVRMYYASKQ-KQYNXXCUSA-N;   Inosin;   SMILES=OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(O)ncnc12;   hypoxanthine D-riboside;   hypoxanthosine;   i;   inosina;   inosinum
 alt_id: CHEBI:14456;   CHEBI:24841;   CHEBI:44407;   CHEBI:5927
 xref: Beilstein:624889;   CAS:58-63-9;   Drug_Central:3301;   ECMDB:ECMDB00195;   Gmelin:489332;   HMDB:HMDB0000195;   KEGG:C00294;   KEGG:D00054;   KNApSAcK:C00019692
 xref_mesh: MESH:D007288
 xref: MetaCyc:INOSINE;   PDBeChem:NOS;   PMID:22770225;   Reaxys:624889;   Wikipedia:Inosine;   YMDB:YMDB00510

show annotations for term's descendants           Sort by:
 
inosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase decreases abundance
increases abundance		 ISO ADA alternative form results in decreased abundance of Inosine
ADA protein results in increased abundance of Inosine		 CTD PMID:16221767 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Faslg Fas ligand increases expression ISO Inosine results in increased expression of FASLG protein CTD PMID:16419169 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Inosine inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form] CTD PMID:32941855 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 multiple interactions ISO
EXP		 Inosine inhibits the reaction [SLC29A1 protein results in increased uptake of Uridine] CTD PMID:9353301 PMID:11085929 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203 		JBrowse link
G Slc29a2 solute carrier family 29 member 2 multiple interactions ISO Inosine inhibits the reaction [SLC29A2 protein results in increased uptake of Uridine] CTD PMID:11085929 NCBI chr 1:202,327,641...202,335,185
Ensembl chr 1:202,327,354...202,335,171 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 multiple interactions ISO Inosine inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein] CTD PMID:32941855 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        biochemical role 19389
          metabolite 19364
            fundamental metabolite 12766
              hypoxanthine 19
                inosine 6
                  1-methylinosine 0
                  2'-O-methylinosine 0
                  2'-deoxyinosine 0
                  3',5'-cyclic IMP 0
                  5'-S-methyl-5'-thioinosine 0
                  5'-deoxyinosine 0
                  6-O-methylinosine 0
                  6-deoxyinosine 5'-phosphate 0
                  7-methylinosine 0
                  Phosphoric acid mono-[(2R,3S,4R,5R)-5-(6-amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl] ester 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            heteroorganic entity 19294
                              organochalcogen compound 19064
                                organooxygen compound 19014
                                  carbohydrates and carbohydrate derivatives 12341
                                    carbohydrate 12341
                                      carbohydrate derivative 11947
                                        glycosyl compound 10977
                                          N-glycosyl compound 5514
                                            nucleoside 5375
                                              ribonucleoside 674
                                                purine ribonucleoside 569
                                                  purines D-ribonucleoside 358
                                                    inosine 6
                                                      1-methylinosine 0
                                                      2'-O-methylinosine 0
                                                      2'-deoxyinosine 0
                                                      3',5'-cyclic IMP 0
                                                      5'-S-methyl-5'-thioinosine 0
                                                      5'-deoxyinosine 0
                                                      6-O-methylinosine 0
                                                      6-deoxyinosine 5'-phosphate 0
                                                      7-methylinosine 0
                                                      Phosphoric acid mono-[(2R,3S,4R,5R)-5-(6-amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl] ester 0
paths to the root