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G |
A4galt |
alpha 1,4-galactosyltransferase |
decreases expression |
ISO |
hydroquinone results in decreased expression of A4GALT mRNA |
CTD |
PMID:31256213 |
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NCBI chr 7:116,248,571...116,272,917
Ensembl chr 7:114,368,276...114,396,071
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G |
Aatf |
apoptosis antagonizing transcription factor |
multiple interactions increases expression increases ADP-ribosylation |
ISO |
PARP1 protein affects the reaction [hydroquinone results in increased expression of AATF protein] hydroquinone results in increased ADP-ribosylation of AATF protein |
CTD |
PMID:26822515 |
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NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201
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G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
increases expression |
ISO |
hydroquinone results in increased expression of ABCC3 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,296,693...79,342,595
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G |
Ace2 |
angiotensin converting enzyme 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of ACE2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr X:33,925,458...33,972,851
Ensembl chr X:30,293,589...30,340,977
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G |
Adam17 |
ADAM metallopeptidase domain 17 |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of ADAM17 protein 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased expression of ADAM17 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA]; ADAM17 protein affects the reaction [hydroquinone results in increased secretion of TNF protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; FOS protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; FOS protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; MIR122 mRNA affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; MIR122 mRNA affects the reaction [hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased expression of ADAM17 protein]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA] |
CTD |
PMID:23791922 |
|
NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:40,872,856...40,920,639
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G |
Adap2 |
ArfGAP with dual PH domains 2 |
increases expression |
ISO |
hydroquinone results in increased expression of ADAP2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604
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G |
Adarb2 |
adenosine deaminase RNA specific B2 |
multiple interactions |
ISO |
hydroquinone inhibits the reaction [Estradiol results in increased expression of ADARB2 mRNA] |
CTD |
PMID:28704378 |
|
NCBI chr17:61,750,437...62,300,984
Ensembl chr17:61,756,067...62,300,831
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G |
Adprh |
ADP-ribosylarginine hydrolase |
increases expression |
ISO |
hydroquinone results in increased expression of ADPRH mRNA |
CTD |
PMID:31256213 |
|
NCBI chr11:75,805,347...75,811,686
Ensembl chr11:62,299,793...62,306,931
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G |
Adtrp |
androgen-dependent TFPI-regulating protein |
increases expression |
ISO |
hydroquinone results in increased expression of ADTRP mRNA |
CTD |
PMID:31256213 |
|
NCBI chr17:23,113,578...23,199,616
Ensembl chr17:22,930,740...22,993,826
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G |
Aen |
apoptosis enhancing nuclease |
increases expression |
ISO |
hydroquinone results in increased expression of AEN mRNA |
CTD |
PMID:23416264 |
|
NCBI chr 1:142,224,499...142,233,902
Ensembl chr 1:132,815,142...132,824,523
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G |
Afap1 |
actin filament associated protein 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of AFAP1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr14:74,743,322...74,856,300
Ensembl chr14:74,743,320...74,856,263
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G |
Aggf1 |
angiogenic factor with G patch and FHA domains 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of AGGF1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 2:26,619,336...26,646,050
Ensembl chr 2:26,619,339...26,645,952
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G |
Ahr |
aryl hydrocarbon receptor |
affects localization multiple interactions increases expression |
ISO EXP |
hydroquinone affects the localization of AHR protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of and affects the localization of AHR protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of AHR protein]; hydroquinone results in increased expression of and affects the localization of AHR protein alpha-naphthoflavone inhibits the reaction [hydroquinone results in increased expression of AHR protein] |
CTD |
PMID:15935814 PMID:29935983 PMID:35123993 |
|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
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G |
Aifm2 |
AIF family member 2 |
increases expression |
ISO |
hydroquinone results in increased expression of AIFM2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr20:30,195,781...30,222,014
Ensembl chr20:29,652,927...29,679,236
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G |
Akr1b10 |
aldo-keto reductase family 1 member B10 |
decreases expression |
ISO |
hydroquinone results in decreased expression of AKR1B10 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:63,040,169...63,053,852
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions decreases phosphorylation |
ISO |
hydroquinone inhibits the reaction [AKT1 protein results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of AKT1 protein]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of AKT1 protein] 4-phenylbutyric acid inhibits the reaction [hydroquinone results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased phosphorylation of AKT1 protein] |
CTD |
PMID:17464197 PMID:28883758 PMID:37148176 |
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NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921
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G |
Akt2 |
AKT serine/threonine kinase 2 |
multiple interactions |
ISO |
hydroquinone inhibits the reaction [AKT2 protein results in increased phosphorylation of IRF3 protein] |
CTD |
PMID:28883758 |
|
NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:82,883,547...82,933,817
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G |
Akt3 |
AKT serine/threonine kinase 3 |
multiple interactions |
ISO |
hydroquinone inhibits the reaction [AKT3 protein results in increased phosphorylation of IRF3 protein] |
CTD |
PMID:28883758 |
|
NCBI chr13:91,475,839...91,758,060
Ensembl chr13:88,946,091...89,225,708
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G |
Alb |
albumin |
multiple interactions |
ISO |
ALB protein binds to and affects the transport of hydroquinone |
CTD |
PMID:8831264 |
|
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836
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G |
Aldh1l2 |
aldehyde dehydrogenase 1 family, member L2 |
increases expression |
ISO |
hydroquinone results in increased expression of ALDH1L2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 7:22,141,872...22,193,403
Ensembl chr 7:20,254,233...20,305,776
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G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
increases expression |
ISO |
hydroquinone results in increased expression of ALDH2 mRNA |
CTD |
PMID:15452088 |
|
NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521
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G |
Aldh3a1 |
aldehyde dehydrogenase 3 family, member A1 |
increases expression |
ISO |
hydroquinone results in increased expression of ALDH3A1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr10:46,392,464...46,402,151
Ensembl chr10:45,892,924...45,902,681
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G |
Alox12 |
arachidonate 12-lipoxygenase, 12S type |
increases expression |
ISO |
hydroquinone results in increased expression of ALOX12 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr10:55,456,923...55,469,239
Ensembl chr10:54,958,271...54,970,542
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G |
Alox12b |
arachidonate 12-lipoxygenase, 12R type |
increases expression |
ISO |
hydroquinone results in increased expression of ALOX12B mRNA |
CTD |
PMID:31256213 |
|
NCBI chr10:54,361,898...54,373,776
Ensembl chr10:53,863,060...53,874,938
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G |
Aloxe3 |
arachidonate epidermal lipoxygenase 3 |
increases expression |
ISO |
hydroquinone results in increased expression of ALOXE3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr10:54,329,224...54,353,167
Ensembl chr10:53,831,264...53,854,328
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G |
Alpk1 |
alpha-kinase 1 |
increases expression |
ISO |
hydroquinone results in increased expression of ALPK1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 2:218,801,425...218,924,013
Ensembl chr 2:216,128,825...216,247,157
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G |
Ambp |
alpha-1-microglobulin/bikunin precursor |
increases expression |
ISO |
hydroquinone results in increased expression of AMBP mRNA |
CTD |
PMID:29221148 |
|
NCBI chr 5:81,583,621...81,593,938
Ensembl chr 5:76,568,094...76,578,331
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G |
Ankdd1a |
ankyrin repeat and death domain containing 1A |
decreases expression |
ISO |
hydroquinone results in decreased expression of ANKDD1A mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 8:74,912,707...74,938,870
Ensembl chr 8:66,017,773...66,042,651
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G |
Anxa1 |
annexin A1 |
increases expression |
ISO |
hydroquinone results in increased expression of ANXA1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:217,861,175...217,877,343
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G |
Anxa3 |
annexin A3 |
increases expression |
ISO |
hydroquinone results in increased expression of ANXA3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr14:13,031,675...13,085,678
Ensembl chr14:12,719,795...12,781,617
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G |
Apoe |
apolipoprotein E |
decreases expression multiple interactions |
EXP |
hydroquinone results in decreased expression of APOE mRNA [[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of APOE mRNA; Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of APOE mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of APOE mRNA] |
CTD |
PMID:33188856 |
|
NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of APP mRNA |
CTD |
PMID:37245849 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561
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G |
Aqp3 |
aquaporin 3 (Gill blood group) |
decreases expression |
ISO |
hydroquinone results in decreased expression of AQP3 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:56,239,201...56,244,720
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G |
Arg1 |
arginase 1 |
increases expression |
ISO |
hydroquinone results in increased expression of ARG1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:20,475,968...20,488,422
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G |
Arg2 |
arginase 2 |
increases expression |
ISO |
hydroquinone results in increased expression of ARG2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 6:103,669,001...103,694,375
Ensembl chr 6:97,936,002...97,961,378
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G |
Arhgap27 |
Rho GTPase activating protein 27 |
increases expression |
ISO |
hydroquinone results in increased expression of ARHGAP27 mRNA |
CTD |
PMID:31256213 |
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NCBI chr10:88,780,527...88,813,275
Ensembl chr10:88,280,455...88,313,185
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G |
Arhgap42 |
Rho GTPase activating protein 42 |
decreases expression |
ISO |
hydroquinone results in decreased expression of ARHGAP42 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 8:6,154,759...6,384,497
Ensembl chr 8:6,156,865...6,384,870
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G |
Arhgdia |
Rho GDP dissociation inhibitor alpha |
affects expression |
ISO |
hydroquinone affects the expression of ARHGDIA protein |
CTD |
PMID:17181942 |
|
NCBI chr10:106,352,858...106,356,347
Ensembl chr10:105,854,533...105,858,023
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G |
Arhgef2 |
Rho/Rac guanine nucleotide exchange factor 2 |
increases expression |
ISO |
hydroquinone results in increased expression of ARHGEF2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:174,062,976...174,118,355
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G |
Arhgef26 |
Rho guanine nucleotide exchange factor 26 |
decreases expression |
ISO |
hydroquinone results in decreased expression of ARHGEF26 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 2:146,740,336...146,850,918
Ensembl chr 2:146,739,631...146,850,819
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G |
Arl3 |
ARF like GTPase 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of ARL3 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 1:245,400,659...245,446,673
Ensembl chr 1:245,400,550...245,446,820
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G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of ARNT protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of ARNT protein] |
CTD |
PMID:35123993 |
|
NCBI chr 2:185,686,703...185,745,546
Ensembl chr 2:182,997,736...183,056,580
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G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
increases expression |
ISO |
hydroquinone results in increased expression of ASNS mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:35,785,237...35,803,423
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G |
Asprv1 |
aspartic peptidase, retroviral-like 1 |
increases expression |
ISO |
hydroquinone results in increased expression of ASPRV1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 4:119,077,415...119,078,887
Ensembl chr 4:119,077,356...119,078,379
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G |
Atf2 |
activating transcription factor 2 |
increases phosphorylation multiple interactions |
ISO |
hydroquinone results in increased phosphorylation of ATF2 protein 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of ATF2 protein]; ATF2 protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; ATF2 protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of TNF protein]; hydroquinone promotes the reaction [ATF2 protein binds to MIR122 promoter]; hydroquinone promotes the reaction [ATF2 protein binds to PPP2CA promoter]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased phosphorylation of ATF2 protein] |
CTD |
PMID:23288922 PMID:23791922 |
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NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:58,718,332...58,795,236
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G |
Atf3 |
activating transcription factor 3 |
increases expression |
ISO |
hydroquinone results in increased expression of ATF3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr13:105,274,103...105,331,653
Ensembl chr13:102,751,321...102,764,631
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G |
Atf4 |
activating transcription factor 4 |
increases expression |
ISO |
hydroquinone results in increased expression of ATF4 mRNA; hydroquinone results in increased expression of ATF4 protein |
CTD |
PMID:15452088 PMID:24053669 |
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NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions decreases expression increases expression |
ISO |
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in decreased expression of ATF6 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of ATF6 protein]; [Sirolimus co-treated with hydroquinone] results in decreased expression of ATF6 protein; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of ATF6 protein]; ATF6 protein affects the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; ATF6 protein affects the reaction [hydroquinone results in increased expression of BAX protein]; ATF6 protein affects the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein] hydroquinone results in decreased expression of ATF6 mRNA; hydroquinone results in decreased expression of ATF6 protein |
CTD |
PMID:36646296 PMID:37148176 |
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NCBI chr13:85,460,312...85,639,959
Ensembl chr13:82,930,034...83,107,177
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G |
Atg12 |
autophagy related 12 |
increases expression |
ISO |
hydroquinone results in increased expression of ATG12 protein |
CTD |
PMID:37148176 |
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NCBI chr18:41,638,841...41,649,311
Ensembl chr18:39,452,191...39,462,418
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G |
Atg5 |
autophagy related 5 |
multiple interactions increases expression |
ISO |
PARP1 protein promotes the reaction [hydroquinone results in increased expression of ATG5 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of ATG5 mRNA] |
CTD |
PMID:28263894 |
|
NCBI chr20:49,380,835...49,471,826
Ensembl chr20:47,798,290...47,889,209
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G |
Atg7 |
autophagy related 7 |
increases expression |
ISO |
hydroquinone results in increased expression of ATG7 protein |
CTD |
PMID:35302183 |
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NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:147,718,752...147,925,593
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G |
Atp2c2 |
ATPase secretory pathway Ca2+ transporting 2 |
increases expression |
ISO |
hydroquinone results in increased expression of ATP2C2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr19:64,662,729...64,719,998
Ensembl chr19:47,754,120...47,811,368
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G |
Atp6v1c2 |
ATPase H+ transporting V1 subunit C2 |
increases expression |
ISO |
hydroquinone results in increased expression of ATP6V1C2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028
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G |
Azgp1 |
alpha-2-glycoprotein 1, zinc-binding |
increases expression |
ISO |
hydroquinone results in increased expression of AZGP1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr12:22,044,685...22,051,248
Ensembl chr12:16,931,024...16,939,091
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G |
Bach1 |
BTB domain and CNC homolog 1 |
multiple interactions decreases expression affects localization |
ISO |
[ferric chloride results in increased oxidation of hydroquinone] promotes the reaction [hydroquinone analog binds to BACH1 protein]; hydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein] hydroquinone results in decreased expression of BACH1 protein hydroquinone affects the localization of BACH1 protein |
CTD |
PMID:23290930 PMID:28645578 |
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NCBI chr11:40,425,721...40,461,118
Ensembl chr11:26,939,480...26,972,447
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G |
Bad |
BCL2-associated agonist of cell death |
decreases expression |
ISO |
hydroquinone results in decreased expression of BAD mRNA |
CTD |
PMID:15452088 |
|
NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823
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G |
Bag1 |
BAG cochaperone 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of BAG1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 5:60,864,476...60,877,059
Ensembl chr 5:56,068,494...56,081,075
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G |
Bambi |
BMP and activin membrane-bound inhibitor |
increases expression |
ISO |
hydroquinone results in increased expression of BAMBI mRNA |
CTD |
PMID:31256213 |
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NCBI chr17:58,816,438...58,821,003
Ensembl chr17:54,121,255...54,126,060
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G |
Bax |
BCL2 associated X, apoptosis regulator |
decreases expression increases expression multiple interactions |
ISO |
hydroquinone results in decreased expression of BAX protein hydroquinone results in increased expression of BAX protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of BAX protein]; 4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction [hydroquinone results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of BAX protein]; [ABT-737 co-treated with hydroquinone] results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of BAX protein]; ATF6 protein affects the reaction [hydroquinone results in increased expression of BAX protein]; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of BAX protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of BAX protein]; Sirolimus promotes the reaction [hydroquinone results in increased expression of BAX protein] |
CTD |
PMID:27515134 PMID:27606422 PMID:28843007 PMID:33771647 PMID:33932074 PMID:35123993 PMID:35561756 PMID:37148176 More...
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NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
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G |
Bbc3 |
Bcl-2 binding component 3 |
increases expression |
ISO |
hydroquinone results in increased expression of BBC3 mRNA |
CTD |
PMID:23416264 |
|
NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:77,014,543...77,022,509
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G |
Bcl11a |
BCL11 transcription factor A |
decreases expression |
ISO |
hydroquinone results in decreased expression of BCL11A mRNA |
CTD |
PMID:31256213 |
|
NCBI chr14:102,230,147...102,325,289
Ensembl chr14:98,030,461...98,124,180
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G |
Bcl11b |
BCL11 transcription factor B |
decreases expression |
ISO |
hydroquinone results in decreased expression of BCL11B mRNA |
CTD |
PMID:31256213 |
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NCBI chr 6:132,598,968...132,692,123
Ensembl chr 6:126,834,531...126,928,224
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Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression increases expression |
ISO |
[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of BCL2 protein; [PARP1 protein co-treated with hydroquinone] results in increased expression of BCL2 protein; CDKN2A protein affects the reaction [hydroquinone results in increased expression of BCL2 protein]; PARP1 protein affects the reaction [hydroquinone results in decreased expression of BCL2 protein] hydroquinone results in decreased expression of BCL2 mRNA; hydroquinone results in decreased expression of BCL2 protein hydroquinone promotes the reaction [XBP1 protein affects the expression of BCL2 mRNA]; XBP1 protein affects the reaction [hydroquinone results in decreased expression of BCL2 mRNA] hydroquinone results in increased expression of BCL2 mRNA; hydroquinone results in increased expression of BCL2 protein |
CTD |
PMID:23288922 PMID:24053669 PMID:27515134 PMID:27606422 PMID:28444915 PMID:28843007 PMID:28983606 PMID:33771647 PMID:33932074 PMID:35123993 PMID:35561756 PMID:37148176 More...
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NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression increases expression |
ISO |
hydroquinone results in decreased expression of BCL2L1 protein hydroquinone results in increased expression of BCL2L1 protein |
CTD |
PMID:23288922 PMID:35561756 |
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NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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G |
Bdh2 |
3-hydroxybutyrate dehydrogenase 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of BDH2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:226,376,346...226,397,010
Ensembl chr 2:223,702,412...223,723,072
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G |
Becn1 |
beclin 1 |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of BECN1 mRNA; hydroquinone results in increased expression of BECN1 protein PARP1 protein promotes the reaction [hydroquinone results in increased expression of BECN1 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of BECN1 mRNA] |
CTD |
PMID:28263894 PMID:35302183 PMID:37148176 |
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NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742
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G |
Bid |
BH3 interacting domain death agonist |
increases cleavage multiple interactions |
ISO |
hydroquinone results in increased cleavage of BID protein FADD protein affects the reaction [hydroquinone results in increased cleavage of BID protein] |
CTD |
PMID:23288922 |
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NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
increases expression decreases expression |
ISO |
hydroquinone results in increased expression of BIRC3 mRNA hydroquinone results in decreased expression of BIRC3 mRNA |
CTD |
PMID:15452088 PMID:31256213 |
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NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:5,000,845...5,015,802
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
decreases expression multiple interactions |
ISO |
hydroquinone results in decreased expression of BIRC5 protein Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of BIRC5 protein] |
CTD |
PMID:28886972 |
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NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380
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G |
Bnip3 |
BCL2 interacting protein 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of BNIP3 mRNA |
CTD |
PMID:15452088 |
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NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:193,708,167...193,725,359
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G |
Bora |
bora, aurora kinase A activator |
decreases expression |
ISO |
hydroquinone results in decreased expression of BORA mRNA |
CTD |
PMID:23416264 |
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NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322
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G |
Bpifc |
BPI fold containing family C |
increases expression |
ISO |
hydroquinone results in increased expression of BPIFC mRNA |
CTD |
PMID:31256213 |
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NCBI chr 7:19,736,282...19,793,737
Ensembl chr 7:17,861,007...17,905,919
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G |
Brca1 |
BRCA1, DNA repair associated |
increases expression |
ISO |
hydroquinone results in increased expression of BRCA1 protein |
CTD |
PMID:29421518 |
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NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,418,000...86,477,304
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G |
Bst2 |
bone marrow stromal cell antigen 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of BST2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr16:18,250,593...18,254,967
Ensembl chr16:18,217,407...18,220,979
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G |
Btg2 |
BTG anti-proliferation factor 2 |
increases expression |
ISO |
hydroquinone results in increased expression of BTG2 mRNA |
CTD |
PMID:23416264 |
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NCBI chr13:48,083,931...48,087,690
Ensembl chr13:45,531,925...45,535,628
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G |
Btrc |
beta-transducin repeat containing E3 ubiquitin protein ligase |
multiple interactions |
ISO |
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC protein]; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC mRNA; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC protein; BTRC protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein]; BTRC protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of SP1 protein]; Chloroquine inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC mRNA]; Dactinomycin promotes the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC mRNA] |
CTD |
PMID:35561756 |
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NCBI chr 1:254,159,085...254,324,819
Ensembl chr 1:244,210,314...244,376,721
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G |
Bub3 |
BUB3 mitotic checkpoint protein |
decreases expression |
ISO |
hydroquinone results in decreased expression of BUB3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:195,760,532...195,771,140
Ensembl chr 1:186,327,931...186,395,036
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G |
C19h16orf74 |
similar to human chromosome 16 open reading frame 74 |
increases expression |
ISO |
hydroquinone results in increased expression of C16ORF74 mRNA |
CTD |
PMID:31256213 |
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NCBI chr19:48,660,288...48,686,287
Ensembl chr19:48,660,288...48,686,349
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G |
C3h15orf48 |
similar to human chromosome 15 open reading frame 48 |
increases expression |
ISO |
hydroquinone results in increased expression of C15ORF48 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:130,173,535...130,177,088
Ensembl chr 3:109,719,897...109,724,006 Ensembl chr 3:109,719,897...109,724,006
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G |
Calb2 |
calbindin 2 |
increases expression |
ISO |
hydroquinone results in increased expression of CALB2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr19:55,023,849...55,050,858
Ensembl chr19:38,114,424...38,141,438
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G |
Calcb |
calcitonin-related polypeptide, beta |
increases expression |
ISO |
hydroquinone results in increased expression of CALCB mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:168,965,383...168,970,259
Ensembl chr 1:168,966,465...168,970,125
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G |
Calhm6 |
calcium homeostasis modulator family member 6 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CALHM6 mRNA |
CTD |
PMID:31256213 |
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NCBI chr20:26,638,721...26,640,466
Ensembl chr20:26,095,592...26,097,278
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G |
Calml3 |
calmodulin-like 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CALML3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr17:71,329,438...71,333,068
Ensembl chr17:66,419,882...66,423,175
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G |
Capn2 |
calpain 2 |
decreases activity |
ISO |
hydroquinone results in decreased activity of CAPN2 protein |
CTD |
PMID:9118890 |
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NCBI chr13:96,681,902...96,732,625
Ensembl chr13:94,150,240...94,200,969
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G |
Car3 |
carbonic anhydrase 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CA3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:86,770,420...86,784,280
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G |
Car9 |
carbonic anhydrase 9 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CA9 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 5:62,559,024...62,565,626
Ensembl chr 5:57,763,206...57,769,838
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G |
Casp1 |
caspase 1 |
increases cleavage multiple interactions |
ISO |
hydroquinone results in increased cleavage of CASP1 protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased cleavage of CASP1 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased cleavage of CASP1 protein] |
CTD |
PMID:36646296 |
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NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp12 |
caspase 12 |
multiple interactions |
ISO |
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of CASP12 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of CASP12 protein] |
CTD |
PMID:36646296 |
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NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:2,642,434...2,674,037
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G |
Casp3 |
caspase 3 |
multiple interactions increases activity increases degradation increases cleavage increases expression decreases activity decreases expression |
ISO EXP |
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of and affects the activity of CASP3 protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP3 protein]; hydroquinone results in decreased expression of and results in increased cleavage of CASP3 protein; IGF1 protein inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form]; NOX4 protein promotes the reaction [hydroquinone results in increased degradation of CASP3 protein]; Okadaic Acid inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; PARP1 protein affects the reaction [hydroquinone results in increased cleavage of CASP3 protein] hydroquinone results in decreased activity of CASP3 protein [hydroquinone results in increased abundance of Reactive Oxygen Species] which results in decreased activity of CASP3 protein hydroquinone results in decreased expression of CASP3 mRNA; hydroquinone results in decreased expression of CASP3 protein |
CTD |
PMID:15337166 PMID:15452088 PMID:15777082 PMID:15816534 PMID:20946948 PMID:22302391 PMID:22960397 PMID:23288922 PMID:23776099 PMID:24053669 PMID:26056850 PMID:26335980 PMID:27515134 PMID:27606422 PMID:28444915 PMID:28886972 PMID:28983606 PMID:35123993 PMID:35302183 PMID:37148176 More...
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NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
increases cleavage |
ISO |
hydroquinone results in increased cleavage of CASP4 protein |
CTD |
PMID:24053669 |
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NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:2,598,876...2,635,092
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G |
Casp6 |
caspase 6 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CASP6 mRNA |
CTD |
PMID:15452088 |
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NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:218,466,076...218,478,502
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G |
Casp7 |
caspase 7 |
increases cleavage increases expression decreases activity multiple interactions |
ISO |
hydroquinone results in increased cleavage of CASP7 protein hydroquinone results in increased expression of CASP7 protein modified form hydroquinone results in decreased activity of CASP7 protein Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP7 protein modified form]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of CASP7 protein] |
CTD |
PMID:19064679 PMID:22960397 PMID:28886972 |
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NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp8 |
caspase 8 |
multiple interactions increases cleavage increases expression increases activity |
ISO |
FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]; MPO protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein]; Okadaic Acid inhibits the reaction [hydroquinone results in increased cleavage of CASP8 protein] hydroquinone results in increased expression of CASP8 protein hydroquinone results in increased activity of CASP8 protein |
CTD |
PMID:15777082 PMID:23288922 PMID:23776099 PMID:27606422 |
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NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
decreases expression increases activity increases expression multiple interactions increases cleavage |
ISO EXP |
hydroquinone results in decreased expression of CASP9 mRNA; hydroquinone results in decreased expression of CASP9 protein hydroquinone results in increased activity of CASP9 protein hydroquinone results in increased expression of CASP9 protein Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of CASP9 protein modified form]; Okadaic Acid inhibits the reaction [hydroquinone results in increased cleavage of CASP9 protein] |
CTD |
PMID:15452088 PMID:15777082 PMID:15816534 PMID:20946948 PMID:22302391 PMID:23288922 PMID:23776099 PMID:26056850 PMID:27606422 PMID:28886972 PMID:37148176 More...
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Ensembl chr 5:154,109,046...154,126,626
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Cat |
catalase |
decreases response to substance decreases activity |
ISO EXP |
CAT protein results in decreased susceptibility to hydroquinone hydroquinone results in decreased activity of CAT protein |
CTD |
PMID:10193577 PMID:26056850 |
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NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
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G |
Cavin2 |
caveolae associated protein 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CAVIN2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147
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G |
Cbs |
cystathionine beta synthase |
increases expression |
ISO |
hydroquinone results in increased expression of CBS mRNA |
CTD |
PMID:31256213 |
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NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,708,090...9,732,764
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G |
Ccdc127 |
coiled-coil domain containing 127 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CCDC127 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:28,928,420...28,935,885
Ensembl chr 1:28,928,325...28,935,893
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G |
Ccdc163 |
coiled-coil domain containing 163 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CCDC163 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 5:135,408,981...135,415,574
Ensembl chr 5:130,172,774...130,178,929
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G |
Ccdc8 |
coiled-coil domain containing 8 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CCDC8 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:77,679,521...77,682,849
Ensembl chr 1:77,679,218...77,683,090
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G |
Ccdc88c |
coiled-coil domain containing 88C |
decreases expression |
ISO |
hydroquinone results in decreased expression of CCDC88C mRNA |
CTD |
PMID:31256213 |
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NCBI chr 6:125,899,337...126,019,162
Ensembl chr 6:120,169,738...120,289,555
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G |
Ccl11 |
C-C motif chemokine ligand 11 |
increases expression |
ISO |
hydroquinone results in increased expression of CCL11 protein |
CTD |
PMID:17572062 |
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NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,028,328...67,032,926
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
decreases secretion decreases expression multiple interactions increases secretion increases expression |
ISO |
hydroquinone results in decreased secretion of CCL2 protein hydroquinone results in decreased expression of CCL2 mRNA hydroquinone inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of CCL2 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL2 mRNA]; hydroquinone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL2 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of CCL2 protein] hydroquinone results in increased secretion of CCL2 protein hydroquinone results in increased expression of CCL2 protein |
CTD |
PMID:17572062 PMID:20946948 PMID:22302391 PMID:22465845 |
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NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
increases expression |
ISO |
hydroquinone results in increased expression of CCL3 protein |
CTD |
PMID:17572062 |
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NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
increases expression |
ISO |
hydroquinone results in increased expression of CCL4 protein |
CTD |
PMID:17572062 PMID:18353026 |
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NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,452,052...68,468,231
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
increases expression |
ISO |
hydroquinone results in increased expression of CCL5 protein |
CTD |
PMID:17572062 |
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NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377
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G |
Ccn1 |
cellular communication network factor 1 |
affects expression |
ISO |
hydroquinone affects the expression of CCN1 mRNA |
CTD |
PMID:15452088 |
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NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:234,562,408...234,565,484
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G |
Ccn2 |
cellular communication network factor 2 |
increases expression |
ISO |
hydroquinone results in increased expression of CCN2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccna1 |
cyclin A1 |
increases expression |
ISO |
hydroquinone results in increased expression of CCNA1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:141,383,352...141,428,205
Ensembl chr 2:139,201,074...139,243,157
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G |
Ccnd1 |
cyclin D1 |
multiple interactions increases expression decreases expression |
ISO |
Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CCND1 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased expression of CCND1 protein] hydroquinone results in increased expression of CCND1 mRNA; hydroquinone results in increased expression of CCND1 protein |
CTD |
PMID:28886972 PMID:33932074 PMID:37951342 |
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NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccne1 |
cyclin E1 |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of CCNE1 protein MIR7-2 promotes the reaction [hydroquinone results in increased expression of CCNE1 protein] |
CTD |
PMID:37951342 |
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NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:90,781,949...90,791,101
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G |
Ccne2 |
cyclin E2 |
increases expression |
ISO |
hydroquinone results in increased expression of CCNE2 mRNA |
CTD |
PMID:23416264 |
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NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:24,284,922...24,297,632
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G |
Ccnf |
cyclin F |
decreases expression |
ISO |
hydroquinone results in decreased expression of CCNF mRNA |
CTD |
PMID:23416264 |
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NCBI chr10:13,757,884...13,783,669
Ensembl chr10:13,253,380...13,279,101
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G |
Ccsap |
centriole, cilia and spindle-associated protein |
decreases expression |
ISO |
hydroquinone results in decreased expression of CCSAP mRNA |
CTD |
PMID:31256213 |
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NCBI chr19:68,722,417...68,740,908
Ensembl chr19:51,826,994...51,842,753
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G |
Cd69 |
Cd69 molecule |
multiple interactions |
ISO |
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD69 protein] |
CTD |
PMID:20054000 |
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NCBI chr 4:164,411,485...164,419,403
Ensembl chr 4:162,725,446...162,733,542
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G |
Cd80 |
Cd80 molecule |
multiple interactions |
ISO |
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein] |
CTD |
PMID:19148301 |
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NCBI chr11:75,760,073...75,798,978
Ensembl chr11:62,254,624...62,292,030
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G |
Cd86 |
CD86 molecule |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of CD86 protein hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 protein] |
CTD |
PMID:19148301 PMID:19665512 |
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NCBI chr11:77,647,565...77,706,178
Ensembl chr11:64,163,828...64,200,818
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G |
Cdca2 |
cell division cycle associated 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CDCA2 mRNA |
CTD |
PMID:23416264 |
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NCBI chr15:46,071,360...46,117,524
Ensembl chr15:41,895,901...41,941,611
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G |
Cdca7 |
cell division cycle associated 7 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CDCA7 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:77,730,315...77,740,950
Ensembl chr 3:57,322,708...57,333,353
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G |
Cdh26 |
cadherin 26 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CDH26 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:185,898,185...185,950,892
Ensembl chr 3:165,520,439...165,572,149
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G |
Cdk2 |
cyclin dependent kinase 2 |
multiple interactions increases expression |
ISO |
MIR7-2 promotes the reaction [hydroquinone results in increased expression of CDK2 protein] |
CTD |
PMID:37951342 |
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NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,129,811...1,137,403
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G |
Cdk4 |
cyclin-dependent kinase 4 |
multiple interactions increases expression |
ISO |
MIR7-2 promotes the reaction [hydroquinone results in increased expression of CDK4 protein] |
CTD |
PMID:37951342 |
|
NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of CDKN1A mRNA; hydroquinone results in increased expression of CDKN1A protein SIRT1 protein affects the reaction [hydroquinone results in increased expression of CDKN1A protein] |
CTD |
PMID:23416264 PMID:27515134 |
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NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1c |
cyclin-dependent kinase inhibitor 1C |
decreases expression |
ISO |
hydroquinone results in decreased expression of CDKN1C mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:198,655,407...198,658,048
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
multiple interactions decreases expression |
ISO |
CDKN2A protein affects the reaction [hydroquinone results in decreased expression of BAX protein]; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of RB1 protein]; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of TP53 protein]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of BCL2 protein]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of CDKN2A protein] hydroquinone results in decreased expression of CDKN2A mRNA; hydroquinone results in decreased expression of CDKN2A protein |
CTD |
PMID:33771647 PMID:33932074 |
|
NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149
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G |
Cdsn |
corneodesmosin |
increases expression |
ISO |
hydroquinone results in increased expression of CDSN mRNA |
CTD |
PMID:31256213 |
|
NCBI chr20:3,179,432...3,184,252
Ensembl chr20:3,179,438...3,184,250
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G |
Cemip |
cell migration inducing hyaluronidase 1 |
increases expression |
ISO |
hydroquinone results in increased expression of CEMIP mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415
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G |
Cenpa |
centromere protein A |
decreases expression |
ISO |
hydroquinone results in decreased expression of CENPA mRNA |
CTD |
PMID:23416264 |
|
NCBI chr 6:31,420,062...31,431,703
Ensembl chr 6:25,700,142...25,711,675
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G |
Cep15 |
centrosomal protein 15 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CEP15 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr15:12,815,159...12,835,115
Ensembl chr15:12,818,385...12,833,838
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G |
Ces1d |
carboxylesterase 1D |
increases expression |
ISO |
hydroquinone results in increased expression of CES1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr19:30,046,494...30,085,039
Ensembl chr19:13,796,623...13,912,035
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G |
Cfap44 |
cilia and flagella associated protein 44 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CFAP44 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr11:69,704,997...69,789,998
Ensembl chr11:56,201,049...56,283,986
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G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
increases expression |
ISO |
hydroquinone results in increased expression of CFLAR mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:60,185,452...60,237,034
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G |
Ch25h |
cholesterol 25-hydroxylase |
increases expression |
ISO |
hydroquinone results in increased expression of CH25H mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 1:241,428,048...241,429,366
Ensembl chr 1:232,014,880...232,016,195
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G |
Chac1 |
ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
increases expression decreases expression |
ISO |
hydroquinone results in increased expression of CHAC1 mRNA hydroquinone results in decreased expression of CHAC1 mRNA |
CTD |
PMID:29221148 PMID:31256213 |
|
NCBI chr 3:126,796,131...126,799,352
Ensembl chr 3:106,342,302...106,345,526
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G |
Chp2 |
calcineurin-like EF hand protein 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CHP2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 1:186,189,090...186,203,663
Ensembl chr 1:176,757,876...176,772,139
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G |
Chst2 |
carbohydrate sulfotransferase 2 |
increases expression |
ISO |
hydroquinone results in increased expression of CHST2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 8:104,839,716...104,845,961
Ensembl chr 8:95,959,826...95,966,955
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G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
multiple interactions |
ISO |
hydroquinone inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein] |
CTD |
PMID:23288922 |
|
NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:242,959,760...242,995,065
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G |
Clca4 |
chloride channel accessory 4 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CLCA4 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 2:236,543,975...236,565,096
Ensembl chr 2:233,883,851...233,903,089
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G |
Cldn8 |
claudin 8 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CLDN8 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr11:41,362,081...41,364,330
Ensembl chr11:27,875,692...27,878,513
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G |
Clic3 |
chloride intracellular channel 3 |
increases expression |
ISO |
hydroquinone results in increased expression of CLIC3 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 3:28,670,176...28,672,166
Ensembl chr 3:8,272,097...8,274,018
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G |
Clmp |
CXADR-like membrane protein |
increases expression |
ISO |
hydroquinone results in increased expression of CLMP mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 8:49,957,639...50,065,959
Ensembl chr 8:41,060,799...41,168,838
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G |
Cmpk2 |
cytidine/uridine monophosphate kinase 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CMPK2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 6:48,802,150...48,813,652
Ensembl chr 6:43,073,796...43,085,183
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G |
Cnfn |
cornifelin |
increases expression |
ISO |
hydroquinone results in increased expression of CNFN mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 1:80,949,699...80,953,747
Ensembl chr 1:80,951,600...80,953,747
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G |
Cnmd |
chondromodulin |
increases response to substance increases expression multiple interactions |
ISO |
CNMD protein results in increased susceptibility to hydroquinone hydroquinone results in increased expression of CNMD mRNA Dactinomycin inhibits the reaction [hydroquinone results in increased expression of CNMD protein]; hydroquinone results in increased expression of and results in increased secretion of CNMD protein; NQO1 protein inhibits the reaction [CNMD protein results in increased susceptibility to hydroquinone]; NQO1 protein inhibits the reaction [hydroquinone results in increased expression of CNMD protein] |
CTD |
PMID:19525446 |
|
NCBI chr15:55,041,548...55,066,297
Ensembl chr15:55,041,561...55,066,297
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G |
Col1a1 |
collagen type I alpha 1 chain |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of COL1A1 protein [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein] |
CTD |
PMID:18055817 |
|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624
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G |
Col2a1 |
collagen type II alpha 1 chain |
multiple interactions |
EXP |
[COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased expression of and results in increased secretion of TNF protein; [COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased secretion of IL1B protein; [COL2A1 protein co-treated with hydroquinone] results in increased expression of IL6 protein |
CTD |
PMID:29908986 PMID:29935983 |
|
NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:129,098,786...129,127,546
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G |
Col4a1 |
collagen type IV alpha 1 chain |
decreases expression increases expression multiple interactions |
ISO |
hydroquinone results in decreased expression of COL4A1 mRNA hydroquinone results in increased expression of COL4A1 protein [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein] |
CTD |
PMID:18055817 |
|
NCBI chr16:84,885,597...84,996,482
Ensembl chr16:78,183,533...78,294,412
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G |
Col5a2 |
collagen type V alpha 2 chain |
decreases expression |
ISO |
hydroquinone results in decreased expression of COL5A2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:47,448,736...47,598,154
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G |
Crct1 |
cysteine-rich C-terminal 1 |
increases expression |
ISO |
hydroquinone results in increased expression of CRCT1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 2:178,633,789...178,635,274
Ensembl chr 2:178,634,092...178,634,394
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions increases phosphorylation |
ISO |
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of CREB1 protein]; CREB1 protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; CREB1 protein affects the reaction [hydroquinone results in increased expression of TNF protein]; hydroquinone promotes the reaction [CREB1 protein binds to PPP2CA promoter] |
CTD |
PMID:23288922 |
|
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816
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G |
Crispld2 |
cysteine-rich secretory protein LCCL domain containing 2 |
increases expression |
ISO |
hydroquinone results in increased expression of CRISPLD2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465
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G |
Crybg2 |
crystallin beta-gamma domain containing 2 |
increases expression |
ISO |
hydroquinone results in increased expression of CRYBG2 mRNA |
CTD |
PMID:29221148 |
|
NCBI chr 5:151,570,154...151,602,164
Ensembl chr 5:146,286,925...146,323,666
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G |
Csf1r |
colony stimulating factor 1 receptor |
multiple interactions |
ISO |
hydroquinone promotes the reaction [[CSF1R protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] |
CTD |
PMID:7884313 |
|
NCBI chr18:56,834,152...56,860,804
Ensembl chr18:54,546,659...54,590,415
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions decreases secretion |
ISO |
[CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK3 protein hydroquinone results in decreased secretion of CSF2 protein hydroquinone promotes the reaction [[CSF2 protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] |
CTD |
PMID:7884313 PMID:15129224 PMID:23559866 |
|
NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,386,945...38,389,199
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G |
Csgalnact1 |
chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
increases expression |
ISO |
hydroquinone results in increased expression of CSGALNACT1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319
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G |
Csrnp3 |
cysteine and serine rich nuclear protein 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CSRNP3 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 3:70,906,587...71,102,596
Ensembl chr 3:50,498,633...50,685,950
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G |
Csrp2 |
cysteine and glycine-rich protein 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of CSRP2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745
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G |
Cst6 |
cystatin E/M |
increases expression |
ISO |
hydroquinone results in increased expression of CST6 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 1:212,084,676...212,086,384
Ensembl chr 1:202,655,322...202,657,030
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G |
Cth |
cystathionine gamma-lyase |
increases expression |
ISO |
hydroquinone results in increased expression of CTH mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:246,975,894...247,002,234
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions affects localization decreases expression |
ISO |
hydroquinone inhibits the reaction [CTNNB1 protein binds to LEF1 protein]; hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein; IGF1 protein inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein] |
CTD |
PMID:28886972 PMID:30567741 |
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NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
decreases expression decreases secretion |
ISO |
hydroquinone results in decreased expression of CXCL12 mRNA hydroquinone results in decreased secretion of CXCL12 protein |
CTD |
PMID:22960397 PMID:23559866 |
|
NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:150,388,325...150,401,168
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G |
Cycs |
cytochrome c, somatic |
affects localization increases expression multiple interactions |
ISO |
hydroquinone affects the localization of CYCS protein hydroquinone results in increased expression of CYCS protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of CYCS protein]; 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of CYCS protein] |
CTD |
PMID:15777082 PMID:15816534 PMID:35123993 |
|
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
affects response to substance multiple interactions increases expression |
ISO |
CYP1A1 protein affects the susceptibility to hydroquinone 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of CYP1A1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of CYP1A1 protein] hydroquinone results in increased expression of CYP1A1 mRNA; hydroquinone results in increased expression of CYP1A1 protein |
CTD |
PMID:8242868 PMID:23416264 PMID:31256213 PMID:35123993 |
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NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
increases expression |
ISO |
hydroquinone results in increased expression of CYP1B1 mRNA |
CTD |
PMID:23416264 PMID:31256213 |
|
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
multiple interactions |
EXP |
[CYP2B1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone |
CTD |
PMID:8211999 |
|
NCBI chr 1:90,646,098...90,669,762
Ensembl chr 1:81,518,408...81,542,052
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G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
affects response to substance |
ISO |
CYP2B1 protein affects the susceptibility to hydroquinone |
CTD |
PMID:8242868 |
|
NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143
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G |
Cyp2d4 |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
multiple interactions |
ISO |
[CYP2D6 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone |
CTD |
PMID:21402134 |
|
NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:113,881,618...113,891,759
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions increases expression |
EXP ISO |
[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone; [CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone; [Glutathione co-treated with [CYP2E1 protein results in increased metabolism of Phenol]] results in increased chemical synthesis of [Glutathione binds to hydroquinone metabolite]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone] hydroquinone results in increased expression of CYP2E1 mRNA Resveratrol inhibits the reaction [hydroquinone results in increased expression of CYP2E1 mRNA] hydroquinone results in increased expression of CYP2E1 mRNA; hydroquinone results in increased expression of CYP2E1 protein [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroquinone; PPP2CA protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein] |
CTD |
PMID:8211999 PMID:15051535 PMID:23202692 PMID:30567741 |
|
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions |
ISO |
[CYP3A4 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone |
CTD |
PMID:21402134 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008
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G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
multiple interactions |
ISO |
[CYP3A5 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone |
CTD |
PMID:21402134 |
|
NCBI chr12:21,919,955...21,960,160
Ensembl chr12:16,806,207...16,846,422
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G |
Cyp4f18 |
cytochrome P450, family 4, subfamily f, polypeptide 18 |
increases expression |
ISO |
hydroquinone results in increased expression of CYP4F18 mRNA; hydroquinone results in increased expression of CYP4F18 protein |
CTD |
PMID:23940708 |
|
NCBI chr16:17,797,558...17,838,958
Ensembl chr16:17,707,317...17,804,940
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G |
Cysrt1 |
cysteine rich tail 1 |
increases expression |
ISO |
hydroquinone results in increased expression of CYSRT1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 3:28,452,359...28,456,006
Ensembl chr 3:8,053,482...8,059,721
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G |
Dap |
death-associated protein |
decreases expression |
ISO |
hydroquinone results in decreased expression of DAP mRNA |
CTD |
PMID:15452088 |
|
NCBI chr 2:83,910,113...83,962,673
Ensembl chr 2:82,199,280...82,251,752
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G |
Dapl1 |
death associated protein-like 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of DAPL1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 3:43,960,993...43,980,940
Ensembl chr 3:43,960,810...43,980,940
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G |
Dapp1 |
dual adaptor of phosphotyrosine and 3-phosphoinositides 1 |
increases expression |
ISO |
hydroquinone results in increased expression of DAPP1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 2:229,099,319...229,148,868
Ensembl chr 2:226,425,898...226,475,423
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G |
Dbt |
dihydrolipoamide branched chain transacylase E2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of DBT mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609
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|
G |
Dcun1d3 |
defective in cullin neddylation 1 domain containing 3 |
increases expression |
ISO |
hydroquinone results in increased expression of DCUN1D3 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 1:183,674,364...183,717,002
Ensembl chr 1:66,494,848...66,496,343 Ensembl chr 1:66,494,848...66,496,343
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G |
Ddah1 |
dimethylarginine dimethylaminohydrolase 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of DDAH1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 2:237,327,812...237,460,624
Ensembl chr 2:234,667,491...234,799,339
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of DDIT3 mRNA; hydroquinone results in increased expression of DDIT3 protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of and affects the localization of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of DDIT3 protein]; hydroquinone results in increased expression of and affects the localization of DDIT3 protein; ursodoxicoltaurine inhibits the reaction [hydroquinone results in increased expression of and affects the localization of DDIT3 protein]; XBP1 protein alternative form inhibits the reaction [hydroquinone results in increased expression of DDIT3 protein] [XBP1 protein affects the susceptibility to hydroquinone] which affects the expression of DDIT3 protein; hydroquinone promotes the reaction [XBP1 protein affects the expression of DDIT3 mRNA]; XBP1 protein affects the reaction [hydroquinone results in increased expression of DDIT3 mRNA]; XBP1 protein affects the reaction [hydroquinone results in increased expression of DDIT3 protein] |
CTD |
PMID:23416264 PMID:24053669 PMID:31256213 PMID:32334435 PMID:36646296 PMID:37148176 More...
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NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201
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Ddit4 |
DNA-damage-inducible transcript 4 |
increases expression |
ISO |
hydroquinone results in increased expression of DDIT4 mRNA |
CTD |
PMID:23416264 |
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NCBI chr20:28,434,938...28,437,037
Ensembl chr20:27,891,998...27,894,105
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Ddx60 |
DEXD/H-box helicase 60 |
decreases expression |
ISO |
hydroquinone results in decreased expression of DDX60 mRNA |
CTD |
PMID:31256213 |
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NCBI chr16:33,087,940...33,208,843
Ensembl chr16:28,076,999...28,179,526
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Depdc7 |
DEP domain containing 7 |
decreases expression |
ISO |
hydroquinone results in decreased expression of DEPDC7 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:111,554,701...111,575,979
Ensembl chr 3:91,099,835...91,121,124
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Deptor |
DEP domain containing MTOR-interacting protein |
decreases expression |
ISO |
hydroquinone results in decreased expression of DEPTOR mRNA |
CTD |
PMID:29221148 |
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NCBI chr 7:88,404,745...88,574,065
Ensembl chr 7:86,514,988...86,667,773
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Dffb |
DNA fragmentation factor subunit beta |
decreases expression |
ISO |
hydroquinone results in decreased expression of DFFB mRNA |
CTD |
PMID:31256213 |
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NCBI chr 5:169,804,873...169,817,157
Ensembl chr 5:164,522,463...164,534,628
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Dkk1 |
dickkopf WNT signaling pathway inhibitor 1 |
affects expression |
ISO |
hydroquinone affects the expression of DKK1 mRNA |
CTD |
PMID:22960397 |
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NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:228,381,521...228,385,202
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Dnaja1 |
DnaJ heat shock protein family (Hsp40) member A1 |
increases expression |
ISO |
hydroquinone results in increased expression of DNAJA1 mRNA |
CTD |
PMID:15452088 |
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NCBI chr 5:60,638,404...60,649,315
Ensembl chr 5:55,842,426...55,853,967
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Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
increases expression |
ISO |
hydroquinone results in increased expression of DNAJB1 mRNA |
CTD |
PMID:15452088 |
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NCBI chr19:41,427,453...41,431,141
Ensembl chr19:24,522,717...24,526,458
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Dner |
delta/notch-like EGF repeat containing |
decreases expression |
ISO |
hydroquinone results in decreased expression of DNER mRNA |
CTD |
PMID:31256213 |
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NCBI chr 9:93,035,108...93,350,568
Ensembl chr 9:85,586,987...85,902,637
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Dnmt1 |
DNA methyltransferase 1 |
decreases expression increases expression affects expression |
ISO |
hydroquinone results in decreased expression of DNMT1 mRNA; hydroquinone results in decreased expression of DNMT1 protein hydroquinone results in increased expression of DNMT1 mRNA hydroquinone affects the expression of DNMT1 mRNA |
CTD |
PMID:22245671 PMID:27979589 PMID:31899212 PMID:34612549 PMID:35135009 |
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NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:19,440,611...19,486,659
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Dnmt3a |
DNA methyltransferase 3 alpha |
decreases expression affects expression increases expression |
ISO |
hydroquinone results in decreased expression of DNMT3A mRNA; hydroquinone results in decreased expression of DNMT3A protein hydroquinone affects the expression of DNMT3A mRNA hydroquinone results in increased expression of DNMT3A mRNA |
CTD |
PMID:22245671 PMID:27979589 PMID:31899212 PMID:34612549 |
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NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:26,822,609...26,896,687
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Dnmt3b |
DNA methyltransferase 3 beta |
decreases expression multiple interactions affects expression |
ISO |
hydroquinone results in decreased expression of DNMT3B mRNA Decitabine affects the reaction [hydroquinone affects the expression of DNMT3B mRNA]; trichostatin A affects the reaction [hydroquinone affects the expression of DNMT3B mRNA] |
CTD |
PMID:22245671 PMID:31899212 PMID:34612549 |
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NCBI chr 3:162,590,777...162,629,313
Ensembl chr 3:142,130,592...142,169,124
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Dtx3l |
deltex E3 ubiquitin ligase 3L |
decreases expression |
ISO |
hydroquinone results in decreased expression of DTX3L mRNA |
CTD |
PMID:31256213 |
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NCBI chr11:78,320,225...78,329,837
Ensembl chr11:64,814,926...64,824,538
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Dusp1 |
dual specificity phosphatase 1 |
increases expression |
ISO |
hydroquinone results in increased expression of DUSP1 protein |
CTD |
PMID:23290930 |
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NCBI chr10:17,184,853...17,187,646
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Dusp19 |
dual specificity phosphatase 19 |
decreases expression |
ISO |
hydroquinone results in decreased expression of DUSP19 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:65,538,424...65,554,465
Ensembl chr 3:65,538,420...65,553,534
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Dusp5 |
dual specificity phosphatase 5 |
increases expression |
ISO |
hydroquinone results in increased expression of DUSP5 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:252,538,449...252,551,818
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G |
Dusp6 |
dual specificity phosphatase 6 |
increases expression |
ISO |
hydroquinone results in increased expression of DUSP6 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:34,092,943...34,097,185
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Dzip1 |
DAZ interacting zinc finger protein 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of DZIP1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr15:102,363,392...102,417,085
Ensembl chr15:95,956,398...96,010,066
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G |
E2f1 |
E2F transcription factor 1 |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of E2F1 mRNA; hydroquinone results in increased expression of E2F1 protein MIR7-2 promotes the reaction [hydroquinone results in increased expression of E2F1 protein] |
CTD |
PMID:33932074 PMID:37951342 |
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NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361
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G |
E4f1 |
E4F transcription factor 1 |
increases expression affects response to substance multiple interactions |
ISO |
hydroquinone results in increased expression of E4F1 mRNA; hydroquinone results in increased expression of E4F1 protein E4F1 protein affects the susceptibility to hydroquinone [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of H2AX protein modified form; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein modified form |
CTD |
PMID:30448557 PMID:30506647 |
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NCBI chr10:13,978,975...13,999,646
Ensembl chr10:13,474,456...13,485,974
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Ecm2 |
extracellular matrix protein 2 |
increases expression |
ISO |
hydroquinone results in increased expression of ECM2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr17:15,326,359...15,358,938
Ensembl chr17:15,120,196...15,152,516
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G |
Edn1 |
endothelin 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of EDN1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,454,420...22,460,885
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G |
Edn2 |
endothelin 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of EDN2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 5:139,036,576...139,042,074
Ensembl chr 5:133,751,217...133,756,814
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G |
Eef2k |
eukaryotic elongation factor-2 kinase |
decreases expression |
ISO |
hydroquinone results in decreased expression of EEF2K mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:184,824,420...184,888,048
Ensembl chr 1:175,393,154...175,455,164
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G |
Efna1 |
ephrin A1 |
multiple interactions |
ISO |
[hydroquinone co-treated with Hemin] affects the expression of EFNA1 mRNA |
CTD |
PMID:32198055 |
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NCBI chr 2:176,979,434...176,988,675
Ensembl chr 2:174,681,682...174,690,866
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G |
Egr3 |
early growth response 3 |
increases expression |
ISO |
hydroquinone results in increased expression of EGR3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr15:51,560,482...51,565,778
Ensembl chr15:45,150,567...45,154,627
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G |
Ehmt2 |
euchromatic histone lysine methyltransferase 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of EHMT2 protein |
CTD |
PMID:27979589 |
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NCBI chr20:3,924,263...3,941,238
Ensembl chr20:3,919,624...3,941,547
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G |
Eid3 |
EP300 interacting inhibitor of differentiation 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of EID3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 7:20,860,073...20,861,395
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
increases phosphorylation increases expression multiple interactions |
ISO |
hydroquinone results in increased phosphorylation of EIF2AK3 protein hydroquinone results in increased expression of EIF2AK3 protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of EIF2AK3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of EIF2AK3 protein] |
CTD |
PMID:24053669 PMID:36646296 |
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NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
multiple interactions increases phosphorylation |
ISO |
XBP1 protein alternative form inhibits the reaction [hydroquinone results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:24053669 PMID:37148176 |
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NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:97,672,766...97,706,225
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
increases expression |
ISO |
hydroquinone results in increased expression of EIF4EBP1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr16:71,495,457...71,508,845
Ensembl chr16:64,790,226...64,805,984
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G |
Elavl1 |
ELAV like RNA binding protein 1 |
multiple interactions increases degradation decreases expression |
ISO |
ELAVL1 protein inhibits the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; ELAVL1 protein inhibits the reaction [hydroquinone results in decreased expression of SIRT3 protein]; ELAVL1 protein inhibits the reaction [hydroquinone results in increased degradation of SIRT3 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 protein]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 mRNA] hydroquinone results in increased degradation of ELAVL1 mRNA hydroquinone results in decreased expression of ELAVL1 mRNA; hydroquinone results in decreased expression of ELAVL1 protein |
CTD |
PMID:35302183 |
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NCBI chr12:7,441,699...7,482,625
Ensembl chr12:2,645,061...2,684,784
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G |
Elavl2 |
ELAV like RNA binding protein 2 |
multiple interactions |
ISO |
[[NOX4 protein results in decreased expression of ELAVL2 protein] which promotes the reaction SIDT2 protein] promotes the reaction [hydroquinone results in decreased degradation of SIRT3 protein] |
CTD |
PMID:35302183 |
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NCBI chr 5:105,960,872...106,086,463
Ensembl chr 5:105,960,875...106,109,097
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G |
Elf3 |
E74 like ETS transcription factor 3 |
increases expression |
ISO |
hydroquinone results in increased expression of ELF3 mRNA |
CTD |
PMID:23416264 |
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NCBI chr13:49,242,265...49,247,102
Ensembl chr13:46,690,466...46,695,481
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G |
Elf5 |
E74 like ETS transcription factor 5 |
increases expression |
ISO |
hydroquinone results in increased expression of ELF5 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:110,264,460...110,291,926
Ensembl chr 3:89,797,880...89,836,973
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G |
Elmod1 |
ELMO domain containing 1 |
increases expression |
ISO |
hydroquinone results in increased expression of ELMOD1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 8:54,298,363...54,355,348
Ensembl chr 8:54,298,363...54,355,140
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G |
Elovl4 |
ELOVL fatty acid elongase 4 |
increases expression |
ISO |
hydroquinone results in increased expression of ELOVL4 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697
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G |
Elovl5 |
ELOVL fatty acid elongase 5 |
decreases expression |
ISO |
hydroquinone results in decreased expression of ELOVL5 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284
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G |
Elp2 |
elongator acetyltransferase complex subunit 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of ELP2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr18:16,160,686...16,196,307
Ensembl chr18:15,885,934...15,921,599
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G |
Epb41l3 |
erythrocyte membrane protein band 4.1-like 3 |
increases expression |
ISO |
hydroquinone results in increased expression of EPB41L3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 9:116,502,864...116,707,274
Ensembl chr 9:109,016,113...109,260,607
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G |
Ephx1 |
epoxide hydrolase 1 |
multiple interactions |
EXP |
EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone] |
CTD |
PMID:8211999 |
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NCBI chr13:95,246,079...95,275,852
Ensembl chr13:92,714,315...92,790,235
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G |
Eps8l1 |
EPS8 signaling adaptor L1 |
increases expression |
ISO |
hydroquinone results in increased expression of EPS8L1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:69,343,202...69,359,778
Ensembl chr 1:69,344,243...69,363,524
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G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of ERBB2 mRNA |
CTD |
PMID:22245671 |
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NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,411,313...83,435,078
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G |
Ereg |
epiregulin |
increases expression |
ISO |
hydroquinone results in increased expression of EREG mRNA |
CTD |
PMID:31256213 |
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NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,027,287...17,041,062
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G |
Erich5 |
glutamate-rich 5 |
decreases expression |
ISO |
hydroquinone results in decreased expression of ERICH5 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 7:67,538,154...67,569,433
Ensembl chr 7:65,657,204...65,680,207
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions increases expression |
ISO |
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of ERN1 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of ERN1 protein] |
CTD |
PMID:36646296 |
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NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029
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G |
Esr1 |
estrogen receptor 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of ESR1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
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G |
Etv4 |
ETS variant transcription factor 4 |
increases expression |
ISO |
hydroquinone results in increased expression of ETV4 mRNA |
CTD |
PMID:31256213 |
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NCBI chr10:87,206,977...87,222,202
Ensembl chr10:86,706,749...86,721,974
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G |
Exosc3 |
exosome component 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of EXOSC3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060
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G |
Exosc6 |
exosome component 6 |
increases expression |
ISO |
hydroquinone results in increased expression of EXOSC6 mRNA |
CTD |
PMID:31256213 |
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NCBI chr19:55,931,523...55,932,937
Ensembl chr19:39,022,183...39,023,515
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G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
decreases expression |
ISO |
hydroquinone results in decreased expression of EZH2 protein |
CTD |
PMID:27979589 |
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NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:76,624,399...76,687,362
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G |
F2r |
coagulation factor II (thrombin) receptor |
decreases expression |
ISO |
hydroquinone results in decreased expression of F2R mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:28,604,066...28,620,579
Ensembl chr 2:26,868,404...26,885,870
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G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions |
ISO |
[KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of FABP4 mRNA |
CTD |
PMID:37245849 |
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NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:91,580,885...91,585,578
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G |
Fadd |
Fas associated via death domain |
decreases expression multiple interactions |
ISO |
hydroquinone results in decreased expression of FADD mRNA FADD protein affects the reaction [hydroquinone results in increased cleavage of BID protein]; FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP3 protein]; FADD protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein] |
CTD |
PMID:15452088 PMID:23288922 |
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NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:199,739,994...199,745,653
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G |
Fahd2a |
fumarylacetoacetate hydrolase domain containing 2A |
decreases expression |
ISO |
hydroquinone results in decreased expression of FAHD2A mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:135,110,480...135,118,653
Ensembl chr 3:114,655,865...114,665,356
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G |
Fam117b |
family with sequence similarity 117, member B |
decreases expression |
ISO |
hydroquinone results in decreased expression of FAM117B mRNA |
CTD |
PMID:31256213 |
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NCBI chr 9:68,834,334...68,902,543
Ensembl chr 9:61,340,249...61,408,483
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G |
Fam13a |
family with sequence similarity 13, member A |
decreases expression |
ISO |
hydroquinone results in decreased expression of FAM13A mRNA |
CTD |
PMID:31256213 |
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NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860
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G |
Fam43a |
family with sequence similarity 43, member A |
increases expression |
ISO |
hydroquinone results in increased expression of FAM43A mRNA |
CTD |
PMID:31256213 |
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NCBI chr11:83,633,165...83,636,313
Ensembl chr11:70,128,253...70,131,401
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G |
Fam83d |
family with sequence similarity 83, member D |
decreases expression |
ISO |
hydroquinone results in decreased expression of FAM83D mRNA |
CTD |
PMID:23416264 |
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NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
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G |
Fas |
Fas cell surface death receptor |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of FAS protein [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of FAS protein |
CTD |
PMID:23776099 PMID:28444915 |
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NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591
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G |
Faslg |
Fas ligand |
increases expression |
ISO |
hydroquinone results in increased expression of FASLG protein |
CTD |
PMID:23776099 |
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NCBI chr13:76,680,885...76,706,042
Ensembl chr13:74,154,954...74,162,215
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G |
Fau |
FAU ubiquitin like and ribosomal protein S30 fusion |
multiple interactions |
ISO |
FAU protein affects the reaction [hydroquinone results in increased expression of and results in increased activity of NQO1 protein]; FAU protein affects the reaction [hydroquinone results in increased expression of H2AX protein] |
CTD |
PMID:22687461 |
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NCBI chr 1:212,779,429...212,781,028
Ensembl chr 1:203,350,189...203,351,742 Ensembl chr 1:203,350,189...203,351,742 Ensembl chr 6:203,350,189...203,351,742
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G |
Fbxo5 |
F-box protein 5 |
decreases expression |
ISO |
hydroquinone results in decreased expression of FBXO5 mRNA |
CTD |
PMID:23416264 |
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NCBI chr 1:44,601,412...44,607,781
Ensembl chr 1:42,196,068...42,202,437
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G |
Fgfr3 |
fibroblast growth factor receptor 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of FGFR3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr14:81,211,800...81,227,215
Ensembl chr14:76,987,993...77,003,341
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G |
Fibin |
fin bud initiation factor homolog |
increases expression |
ISO |
hydroquinone results in increased expression of FIBIN mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676
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G |
Flg |
filaggrin |
increases expression |
ISO |
hydroquinone results in increased expression of FLG mRNA; hydroquinone results in increased expression of FLG protein |
CTD |
PMID:25240866 |
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NCBI chr 2:181,583,801...181,596,464
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G |
Flg2 |
filaggrin 2 |
increases expression |
ISO |
hydroquinone results in increased expression of FLG2 mRNA |
CTD |
PMID:25240866 |
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NCBI chr 2:178,789,792...178,802,232
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G |
Fn1 |
fibronectin 1 |
affects expression |
ISO |
hydroquinone affects the expression of FN1 mRNA |
CTD |
PMID:15452088 |
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NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:73,196,044...73,264,678
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
decreases expression increases phosphorylation multiple interactions |
ISO |
hydroquinone results in decreased expression of FOS mRNA hydroquinone results in increased phosphorylation of FOS protein 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of FOS protein]; FOS protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; FOS protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; FOS protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; hydroquinone promotes the reaction [FOS protein binds to MIR122 promoter] |
CTD |
PMID:15452088 PMID:23791922 |
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NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
increases expression |
ISO |
hydroquinone results in increased expression of FOSL1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:202,754,529...202,764,930
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G |
Fry |
FRY microtubule binding protein |
increases expression |
ISO |
hydroquinone results in increased expression of FRY mRNA |
CTD |
PMID:31256213 |
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NCBI chr12:9,530,360...9,773,391
Ensembl chr12:4,493,891...4,799,116
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G |
Fsip1 |
fibrous sheath interacting protein 1 |
increases expression |
ISO |
hydroquinone results in increased expression of FSIP1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:105,074,584...105,217,180
Ensembl chr 3:105,068,543...105,217,167
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G |
Fth1 |
ferritin heavy chain 1 |
increases expression |
ISO |
hydroquinone results in increased expression of FTH1 mRNA; hydroquinone results in increased expression of FTH1 protein |
CTD |
PMID:15452088 PMID:23738040 |
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NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:206,627,103...206,725,424
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G |
Fut1 |
fucosyltransferase 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of FUT1 mRNA |
CTD |
PMID:29221148 |
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NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616
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G |
Fzd2 |
frizzled class receptor 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of FZD2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr10:88,061,988...88,063,898
Ensembl chr10:87,561,326...87,565,334
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G |
G0s2 |
G0/G1switch 2 |
increases expression |
ISO |
hydroquinone results in increased expression of G0S2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
ISO |
hydroquinone results in increased expression of GADD45A mRNA |
CTD |
PMID:23416264 |
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NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115
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G |
Gas1 |
growth arrest-specific 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of GAS1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr17:4,482,168...4,485,153
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G |
Gask1b |
golgi associated kinase 1B |
decreases expression |
ISO |
hydroquinone results in decreased expression of GASK1B mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:167,345,738...167,410,606
Ensembl chr 2:165,047,684...165,112,477
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G |
Gata1 |
GATA binding protein 1 |
decreases expression multiple interactions |
ISO |
hydroquinone results in decreased expression of GATA1 mRNA Decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]]; hydroquinone inhibits the reaction [GATA1 protein binds to HBA1 gene]; hydroquinone inhibits the reaction [GATA1 protein binds to HBD gene]; hydroquinone inhibits the reaction [GATA1 protein binds to HBG1 gene]; hydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA] |
CTD |
PMID:21414390 PMID:23973255 PMID:37329354 |
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NCBI chr X:17,193,291...17,209,462
Ensembl chr X:14,529,702...14,537,530
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G |
Gata2 |
GATA binding protein 2 |
multiple interactions decreases expression |
ISO |
hydroquinone affects the reaction [Hemin affects the expression of GATA2 mRNA]; hydroquinone inhibits the reaction [Hemin results in decreased expression of GATA2 protein]; hydroquinone promotes the reaction [GATA2 protein binds to HBB gene]; hydroquinone promotes the reaction [GATA2 protein binds to HBG2 gene]; hydroquinone promotes the reaction [GATA2 protein binds to HBM gene]; hydroquinone promotes the reaction [GATA2 protein binds to HBP1 gene]; hydroquinone promotes the reaction [Hemin results in decreased expression of GATA2 mRNA] hydroquinone results in decreased expression of GATA2 mRNA |
CTD |
PMID:21414390 PMID:37329354 |
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NCBI chr 4:122,211,501...122,225,058
Ensembl chr 4:120,658,986...120,667,761
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G |
Gbp2 |
guanylate binding protein 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of GBP2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:231,332,284...231,348,571
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression multiple interactions affects methylation |
ISO |
hydroquinone results in increased expression of GCLC mRNA; hydroquinone results in increased expression of GCLC protein [hydroquinone affects the methylation of GCLC promoter] which results in decreased abundance of 5-Methylcytosine; [hydroquinone affects the methylation of GCLC promoter] which results in increased abundance of 5-hydroxymethylcytosine; Resveratrol promotes the reaction [hydroquinone results in increased expression of GCLC mRNA]; TET1 protein affects the reaction [hydroquinone results in increased expression of GCLC mRNA] |
CTD |
PMID:23290930 PMID:23940045 PMID:30547568 PMID:32334435 |
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NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
increases expression |
ISO |
hydroquinone results in increased expression of GCLM mRNA; hydroquinone results in increased expression of GCLM protein |
CTD |
PMID:21059386 PMID:30547568 PMID:31256213 |
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NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535
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G |
Gda |
guanine deaminase |
increases expression |
ISO |
hydroquinone results in increased expression of GDA mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:228,333,401...228,408,901
Ensembl chr 1:218,906,815...218,982,416
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G |
Gdf15 |
growth differentiation factor 15 |
increases expression |
ISO |
hydroquinone results in increased expression of GDF15 mRNA |
CTD |
PMID:23416264 PMID:31256213 |
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NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,805,239...18,808,055
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G |
Gdpd3 |
glycerophosphodiester phosphodiesterase domain containing 3 |
increases expression |
ISO |
hydroquinone results in increased expression of GDPD3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:190,804,053...190,813,609
Ensembl chr 1:181,366,626...181,383,063
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G |
Gfpt1 |
glutamine fructose-6-phosphate transaminase 1 |
increases expression |
ISO |
hydroquinone results in increased expression of GFPT1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 4:121,054,023...121,103,799
Ensembl chr 4:119,496,714...119,546,471
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G |
Gk |
glycerol kinase |
increases expression |
ISO |
hydroquinone results in increased expression of GK mRNA |
CTD |
PMID:31256213 |
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NCBI chr X:54,106,708...54,189,940
Ensembl chr X:50,163,123...50,238,631
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G |
Glmp |
glycosylated lysosomal membrane protein |
decreases expression |
ISO |
hydroquinone results in decreased expression of GLMP mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:176,092,098...176,095,688
Ensembl chr 2:173,794,255...173,799,960
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G |
Glrx |
glutaredoxin |
increases expression |
ISO |
hydroquinone results in increased expression of GLRX mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:7,073,737...7,083,548
Ensembl chr 2:5,341,885...5,351,680
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G |
Glul |
glutamate-ammonia ligase |
decreases expression |
ISO |
hydroquinone results in decreased expression of GLUL mRNA |
CTD |
PMID:31256213 |
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NCBI chr13:68,519,500...68,585,554
Ensembl chr13:66,025,630...66,035,108
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G |
Gmpr |
guanosine monophosphate reductase |
decreases expression |
ISO |
hydroquinone results in decreased expression of GMPR mRNA |
CTD |
PMID:31256213 |
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NCBI chr17:19,357,992...19,395,807
Ensembl chr17:19,151,815...19,189,621
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G |
Gosr2 |
golgi SNAP receptor complex member 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of GOSR2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr10:89,085,323...89,105,665
Ensembl chr10:88,586,299...88,605,625
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G |
Got1 |
glutamic-oxaloacetic transaminase 1 |
increases expression |
ISO |
hydroquinone results in increased expression of GOT1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:242,357,306...242,380,633
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G |
Gpat3 |
glycerol-3-phosphate acyltransferase 3 |
increases expression |
ISO |
hydroquinone results in increased expression of GPAT3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr14:9,018,762...9,072,552
Ensembl chr14:8,714,373...8,766,490
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G |
Gpr155 |
G protein-coupled receptor 155 |
decreases expression |
ISO |
hydroquinone results in decreased expression of GPR155 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:78,623,931...78,677,803
Ensembl chr 3:58,216,423...58,270,275
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G |
Gpr15lg |
G protein-coupled receptor 15 ligand |
decreases expression |
ISO |
hydroquinone results in decreased expression of GPR15LG mRNA |
CTD |
PMID:31256213 |
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NCBI chr16:12,888,528...12,896,134
Ensembl chr16:12,868,270...12,875,876
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G |
Gprc5a |
G protein-coupled receptor, class C, group 5, member A |
decreases expression |
ISO |
hydroquinone results in decreased expression of GPRC5A mRNA |
CTD |
PMID:31256213 |
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NCBI chr 4:169,634,896...169,653,627
Ensembl chr 4:167,903,542...167,922,260
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G |
Gpx2 |
glutathione peroxidase 2 |
increases expression |
ISO |
hydroquinone results in increased expression of GPX2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:95,493,589...95,496,877
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G |
Grb10 |
growth factor receptor bound protein 10 |
increases expression |
ISO |
hydroquinone results in increased expression of GRB10 mRNA |
CTD |
PMID:31256213 |
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NCBI chr14:90,708,653...90,816,399
Ensembl chr14:86,495,054...86,602,806
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G |
Grb2 |
growth factor receptor bound protein 2 |
affects expression |
ISO |
hydroquinone affects the expression of GRB2 protein |
CTD |
PMID:20021034 |
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NCBI chr10:101,380,354...101,448,138
Ensembl chr10:100,869,718...100,949,309
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G |
Grhl1 |
grainyhead-like transcription factor 1 |
increases expression |
ISO |
hydroquinone results in increased expression of GRHL1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 6:46,935,947...46,986,126
Ensembl chr 6:41,207,348...41,254,301
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G |
Gsdmd |
gasdermin D |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of GSDMD protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of GSDMD protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of GSDMD protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of GSDMD protein] |
CTD |
PMID:36646296 |
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NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:107,542,083...107,547,055
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
ISO |
hydroquinone results in increased expression of and results in decreased phosphorylation of and results in increased activity of GSK3B protein; IGF1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [hydroquinone results in increased expression of GSK3B protein] |
CTD |
PMID:28886972 |
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NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions |
ISO |
hydroquinone inhibits the reaction [Peroxynitrous Acid results in decreased activity of GSR protein] |
CTD |
PMID:15831208 |
|
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661
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G |
Gss |
glutathione synthetase |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of GSS protein NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of GSS protein] |
CTD |
PMID:21059386 |
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NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:144,047,850...144,078,198
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G |
Gstm1 |
glutathione S-transferase mu 1 |
affects response to substance |
ISO |
GSTM1 affects the susceptibility to hydroquinone; GSTM1 gene polymorphism affects the susceptibility to hydroquinone |
CTD |
PMID:15141365 PMID:19778234 |
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NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:195,649,845...195,655,411
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G |
Gstp1 |
glutathione S-transferase pi 1 |
affects response to substance |
ISO |
GSTP1 affects the susceptibility to hydroquinone |
CTD |
PMID:19778234 |
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NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226
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G |
Gstt1 |
glutathione S-transferase theta 1 |
increases expression affects response to substance |
ISO |
hydroquinone results in increased expression of GSTT1 mRNA GSTT1 affects the susceptibility to hydroquinone |
CTD |
PMID:19778234 PMID:23290930 |
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NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,669...12,873,585
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G |
Gtpbp2 |
GTP binding protein 2 |
increases expression |
ISO |
hydroquinone results in increased expression of GTPBP2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 9:22,311,532...22,321,405
Ensembl chr 9:14,813,964...14,823,241
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G |
Gucy1b1 |
guanylate cyclase 1 soluble subunit beta 1 |
increases expression |
ISO |
hydroquinone results in increased expression of GUCY1B1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:169,646,897...169,697,060
Ensembl chr 2:167,348,825...167,398,916
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G |
Gvin1 |
GTPase, very large interferon inducible 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of GVINP1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:160,279,767...160,306,701
Ensembl chr 1:160,277,126...160,306,331
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G |
Gypa |
glycophorin A |
decreases expression |
ISO |
hydroquinone results in decreased expression of GYPA protein |
CTD |
PMID:21414390 |
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NCBI chr19:27,450,304...27,465,940
Ensembl chr19:27,450,308...27,465,822
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G |
H1f4 |
H1.4 linker histone, cluster member |
decreases expression |
ISO |
hydroquinone results in decreased expression of H1-4 mRNA |
CTD |
PMID:23416264 |
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NCBI chr17:41,914,425...41,915,206
Ensembl chr17:41,486,560...41,487,403
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G |
H1f5 |
H1.5 linker histone, cluster member |
decreases expression |
ISO |
hydroquinone results in decreased expression of H1-5 mRNA |
CTD |
PMID:23416264 |
|
NCBI chr17:47,421,875...47,422,905
Ensembl chr17:42,726,127...42,769,160
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G |
H2ac12 |
H2A clustered histone 12 |
decreases expression |
ISO |
hydroquinone results in decreased expression of H2AC12 mRNA |
CTD |
PMID:23416264 |
|
NCBI chr17:47,182,193...47,182,658
Ensembl chr17:42,486,415...42,486,941
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G |
H2ac18 |
H2A clustered histone 18 |
decreases expression |
ISO |
hydroquinone results in decreased expression of H2AC18 mRNA |
CTD |
PMID:23416264 |
|
NCBI chr 2:186,497,271...186,497,865
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G |
H2ac20 |
H2A clustered histone 20 |
decreases expression |
ISO |
hydroquinone results in decreased expression of H2AC20 mRNA |
CTD |
PMID:23416264 |
|
NCBI chr 2:186,468,748...186,469,226
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G |
H2ac21 |
H2A clustered histone 21 |
decreases expression |
ISO |
hydroquinone results in decreased expression of H2AC21 mRNA |
CTD |
PMID:23416264 |
|
NCBI chr 2:186,468,224...186,468,657
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G |
H2ax |
H2A.X variant histone |
multiple interactions increases expression increases phosphorylation affects localization |
ISO |
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of H2AX protein]; 2-tert-butylhydroquinone inhibits the reaction [hydroquinone results in increased expression of H2AX protein]; [ABT-737 co-treated with hydroquinone] results in increased expression of H2AX protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of H2AX protein modified form; [SIRT1 protein affects the susceptibility to hydroquinone] which affects the expression of H2AX protein; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of H2AX protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of H2AX protein]; POLH protein affects the reaction [hydroquinone results in increased expression of H2AX protein]; WRN gene mutant form promotes the reaction [hydroquinone results in increased expression of H2AX protein alternative form]; WRN protein affects the reaction [hydroquinone results in increased expression of H2AX protein] FAU protein affects the reaction [hydroquinone results in increased expression of H2AX protein] hydroquinone results in increased phosphorylation of H2AX protein hydroquinone affects the localization of H2AX protein modified form hydroquinone results in increased expression of H2AX protein; hydroquinone results in increased expression of H2AX protein alternative form |
CTD |
PMID:17875398 PMID:18835433 PMID:20036648 PMID:21267443 PMID:22687461 PMID:22981619 PMID:23940708 PMID:26335980 PMID:26822515 PMID:27515134 PMID:28843007 PMID:30506647 PMID:35123993 More...
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NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:44,671,786...44,673,239 Ensembl chr 4:44,671,786...44,673,239
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G |
H4c14 |
H4 clustered histone 14 |
decreases expression |
ISO |
hydroquinone results in decreased expression of H4C2 mRNA |
CTD |
PMID:23416264 |
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NCBI chr 2:186,520,468...186,520,863
Ensembl chr 2:183,825,994...183,832,048
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G |
H4cl1 |
histone H4C like 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of H4C6 mRNA |
CTD |
PMID:23416264 |
|
NCBI chr17:41,796,600...41,860,389
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G |
H4f3 |
H1.3 linker histone, cluster member |
decreases expression |
ISO |
hydroquinone results in decreased expression of H1-3 mRNA |
CTD |
PMID:23416264 |
|
NCBI chr17:41,979,562...41,980,341
Ensembl chr17:41,529,667...41,552,334
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G |
Hba-a2 |
hemoglobin alpha, adult chain 2 |
multiple interactions |
ISO |
hydroquinone inhibits the reaction [GATA1 protein binds to HBA1 gene] |
CTD |
PMID:37329354 |
|
NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,307,815...15,338,392 Ensembl chr10:15,307,815...15,338,392
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G |
Hbb |
hemoglobin subunit beta |
multiple interactions decreases methylation |
ISO |
Decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]; hydroquinone promotes the reaction [GATA2 protein binds to HBB gene] hydroquinone results in decreased methylation of HBB promoter |
CTD |
PMID:21414390 PMID:23973255 PMID:37329354 |
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NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:158,120,200...158,252,012
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G |
Hbb-b1 |
hemoglobin, beta adult major chain |
multiple interactions |
ISO |
hydroquinone inhibits the reaction [GATA1 protein binds to HBD gene] |
CTD |
PMID:37329354 |
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NCBI chr 1:167,636,064...167,643,577
Ensembl chr 1:158,120,200...158,252,012
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G |
Hbegf |
heparin-binding EGF-like growth factor |
increases expression |
ISO |
hydroquinone results in increased expression of HBEGF mRNA |
CTD |
PMID:31256213 |
|
NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,105,760...28,116,441
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G |
Hbg1 |
hemoglobin subunit gamma 1 |
multiple interactions |
ISO |
hydroquinone inhibits the reaction [GATA1 protein binds to HBG1 gene] |
CTD |
PMID:37329354 |
|
NCBI chr 1:167,683,760...167,685,315
Ensembl chr 1:158,271,873...158,273,425
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G |
Hbp1 |
HMG-box transcription factor 1 |
multiple interactions |
ISO |
hydroquinone promotes the reaction [GATA2 protein binds to HBP1 gene] |
CTD |
PMID:37329354 |
|
NCBI chr 6:54,257,118...54,283,373
Ensembl chr 6:48,529,372...48,555,787
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G |
Hdac1 |
histone deacetylase 1 |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of HDAC1 mRNA; hydroquinone results in increased expression of HDAC1 protein trichostatin A inhibits the reaction [hydroquinone results in increased expression of HDAC1 mRNA] |
CTD |
PMID:27220438 PMID:30448557 |
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NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:141,853,989...141,881,111
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G |
Hdac2 |
histone deacetylase 2 |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of HDAC2 mRNA; hydroquinone results in increased expression of HDAC2 protein trichostatin A inhibits the reaction [hydroquinone results in increased expression of HDAC2 mRNA] |
CTD |
PMID:27220438 PMID:30448557 |
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NCBI chr20:42,101,815...42,126,486
Ensembl chr20:40,548,250...40,571,609
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G |
Hdac9 |
histone deacetylase 9 |
increases expression |
ISO |
hydroquinone results in increased expression of HDAC9 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 6:56,489,472...57,351,654
Ensembl chr 6:50,763,590...51,625,333
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G |
Hfe |
homeostatic iron regulator |
decreases expression |
ISO |
hydroquinone results in decreased expression of HFE mRNA |
CTD |
PMID:31256213 |
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NCBI chr17:41,841,302...41,849,359
Ensembl chr17:41,413,451...41,421,502
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G |
Hist1h4m |
histone cluster 1, H4m |
decreases expression |
ISO |
hydroquinone results in decreased expression of H4C1 mRNA |
CTD |
PMID:23416264 |
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NCBI chr17:47,393,764...47,394,168
Ensembl chr17:42,698,025...42,698,958
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G |
Hjurp |
Holliday junction recognition protein |
decreases expression |
ISO |
hydroquinone results in decreased expression of HJURP mRNA |
CTD |
PMID:23416264 |
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NCBI chr 9:96,301,183...96,315,587
Ensembl chr 9:88,853,386...88,867,728
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G |
Hmbs |
hydroxymethylbilane synthase |
multiple interactions |
ISO |
decitabine inhibits the reaction [hydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA]]; hydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA] |
CTD |
PMID:21414390 PMID:23973255 |
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NCBI chr 8:53,570,364...53,577,758
Ensembl chr 8:44,673,554...44,680,957
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G |
Hmgb2 |
high mobility group box 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of HMGB2 mRNA |
CTD |
PMID:23416264 |
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NCBI chr16:37,721,374...37,723,950
Ensembl chr16:32,710,658...32,713,140 Ensembl chr 1:32,710,658...32,713,140
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of HMOX1 mRNA; hydroquinone results in increased expression of HMOX1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; AG 1879 inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; bisindolylmaleimide I inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; Cysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Dithiothreitol inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Staurosporine inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; Staurosporine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Wortmannin inhibits the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; Wortmannin inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein] 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; [Resveratrol co-treated with hydroquinone] results in increased expression of HMOX1 protein; ferric chloride promotes the reaction [hydroquinone results in increased expression of HMOX1 protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]; Resveratrol promotes the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; risuteganib promotes the reaction [hydroquinone results in increased expression of HMOX1 mRNA]; risuteganib promotes the reaction [hydroquinone results in increased expression of HMOX1 protein]; S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein] |
CTD |
PMID:17464197 PMID:21059386 PMID:23290930 PMID:28645578 PMID:29508652 PMID:30547568 PMID:31256213 PMID:32141582 PMID:32334435 PMID:32818234 PMID:36646296 More...
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NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
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G |
Hotairm1 |
Hoxa transcript antisense RNA, myeloid-specific 1 |
multiple interactions affects expression affects methylation |
ISO |
Decitabine affects the reaction [hydroquinone affects the expression of HOTAIRM1 mRNA]; Decitabine affects the reaction [hydroquinone affects the methylation of HOTAIRM1 promoter]; trichostatin A affects the reaction [hydroquinone affects the expression of HOTAIRM1 mRNA]; trichostatin A affects the reaction [hydroquinone affects the methylation of HOTAIRM1 promoter] |
CTD |
PMID:31899212 |
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NCBI chr 4:81,258,793...81,262,291
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G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions affects expression |
ISO |
3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of HRAS protein]; Doxorubicin inhibits the reaction [hydroquinone results in decreased expression of HRAS protein]; hydroquinone promotes the reaction [PARP1 protein binds to and results in increased ADP-ribosylation of and results in increased expression of HRAS protein]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of HRAS protein] hydroquinone affects the expression of HRAS mRNA; hydroquinone affects the expression of HRAS protein |
CTD |
PMID:26047893 |
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NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615
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G |
Hsd17b2 |
hydroxysteroid (17-beta) dehydrogenase 2 |
increases expression |
ISO |
hydroquinone results in increased expression of HSD17B2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr19:62,662,320...62,733,944
Ensembl chr19:45,753,574...45,825,202
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G |
Hspa13 |
heat shock protein family A (Hsp70) member 13 |
increases expression |
ISO |
hydroquinone results in increased expression of HSPA13 mRNA |
CTD |
PMID:31256213 |
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NCBI chr11:27,862,717...27,876,898
Ensembl chr11:14,373,275...14,389,895
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G |
Hspa2 |
heat shock protein family A (Hsp70) member 2 |
increases expression |
ISO |
hydroquinone results in increased expression of HSPA2 mRNA |
CTD |
PMID:15452088 |
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NCBI chr 6:100,864,172...100,866,946
Ensembl chr 6:95,128,350...95,131,287
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of HSPA5 protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of HSPA5 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of HSPA5 protein] |
CTD |
PMID:24053669 PMID:36646296 PMID:37148176 |
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NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891
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G |
Htr1a |
5-hydroxytryptamine receptor 1A |
decreases expression |
ISO |
hydroquinone results in decreased expression of HTR1A protein |
CTD |
PMID:27606422 |
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NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:36,694,174...36,695,442
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G |
Htr1b |
5-hydroxytryptamine receptor 1B |
decreases expression |
ISO |
hydroquinone results in decreased expression of HTR1B protein |
CTD |
PMID:27606422 |
|
NCBI chr 8:91,395,405...91,414,815
Ensembl chr 8:82,517,360...82,534,549
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G |
Hyls1 |
HYLS1, centriolar and ciliogenesis associated |
decreases expression |
ISO |
hydroquinone results in decreased expression of HYLS1 mRNA |
CTD |
PMID:23416264 |
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NCBI chr 8:42,170,505...42,179,573
Ensembl chr 8:33,912,692...33,921,760
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G |
Id1 |
inhibitor of DNA binding 1 |
increases expression |
ISO |
hydroquinone results in increased expression of ID1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:141,211,267...141,212,419
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G |
Id3 |
inhibitor of DNA binding 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of ID3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:148,372,762...148,374,349
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G |
Id4 |
inhibitor of DNA binding 4 |
increases expression |
ISO |
hydroquinone results in increased expression of ID4 mRNA |
CTD |
PMID:31256213 |
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NCBI chr17:16,595,724...16,598,293
Ensembl chr17:16,389,387...16,392,470
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G |
Ier3 |
immediate early response 3 |
increases expression |
ISO |
hydroquinone results in increased expression of IER3 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,928,378...2,929,583
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G |
Ifi44 |
interferon-induced protein 44 |
decreases expression |
ISO |
hydroquinone results in decreased expression of IFI44 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 2:243,286,050...243,303,869
Ensembl chr 2:240,626,066...240,643,844
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G |
Ifi44l |
interferon-induced protein 44-like |
decreases expression |
ISO |
hydroquinone results in decreased expression of IFI44L mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 2:243,328,629...243,366,404
Ensembl chr 2:240,668,713...240,706,359
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G |
Ifih1 |
interferon induced with helicase C domain 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of IFIH1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:67,635,924...67,683,968
Ensembl chr 3:47,227,364...47,275,456
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G |
Ifit3 |
interferon-induced protein with tetratricopeptide repeats 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of IFIT3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:232,114,166...232,119,307
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G |
Ifitm1 |
interferon induced transmembrane protein 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of IFITM1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 1:205,496,757...205,498,796
Ensembl chr 1:196,067,963...196,069,169
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G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
hydroquinone inhibits the reaction [[IFNG protein co-treated with lipopolysaccharide, E. coli O26-B6] results in increased secretion of CCL2 protein]; hydroquinone inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased expression of IFNG protein]; IFNG protein promotes the reaction [[Lipopolysaccharides co-treated with hydroquinone] results in increased abundance of Nitric Oxide] |
CTD |
PMID:3137358 PMID:7884313 PMID:22465845 |
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NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375
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G |
Ifrd1 |
interferon-related developmental regulator 1 |
increases expression |
ISO |
hydroquinone results in increased expression of IFRD1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 6:62,996,560...63,044,996
Ensembl chr 6:57,269,384...57,288,990
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G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions |
ISO |
IGF1 protein inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein]; IGF1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of GSK3B protein]; IGF1 protein inhibits the reaction [hydroquinone results in increased expression of CASP3 protein modified form] |
CTD |
PMID:28886972 |
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NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of IGFBP3 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr14:86,270,208...86,277,944
Ensembl chr14:82,056,347...82,064,083
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions |
ISO |
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] |
CTD |
PMID:20054000 |
|
NCBI chr16:76,021,968...76,075,717
Ensembl chr16:69,319,554...69,373,250
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G |
Il10 |
interleukin 10 |
multiple interactions increases secretion |
ISO |
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA] hydroquinone results in increased secretion of IL10 protein hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein] |
CTD |
PMID:17464197 PMID:17572062 PMID:23559866 |
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NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313
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G |
Il12b |
interleukin 12B |
multiple interactions increases expression |
ISO |
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] hydroquinone results in increased expression of IL12B mRNA |
CTD |
PMID:15894107 PMID:17464197 |
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NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903
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G |
Il15 |
interleukin 15 |
decreases secretion |
ISO |
hydroquinone results in decreased secretion of IL15 protein |
CTD |
PMID:23559866 |
|
NCBI chr19:42,536,160...42,611,349
Ensembl chr19:25,640,251...25,706,820
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G |
Il17a |
interleukin 17A |
increases secretion |
EXP |
hydroquinone results in increased secretion of IL17A protein |
CTD |
PMID:29935983 |
|
NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:23,144,402...23,147,889
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G |
Il18 |
interleukin 18 |
multiple interactions increases secretion |
ISO |
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased secretion of IL18 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased secretion of IL18 protein] |
CTD |
PMID:36646296 |
|
NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1a |
interleukin 1 alpha |
multiple interactions increases expression decreases cleavage |
ISO |
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased cleavage of IL1A protein] Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of IL1A protein]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein] hydroquinone results in increased expression of IL1A mRNA; hydroquinone results in increased expression of IL1A protein hydroquinone results in decreased cleavage of IL1A protein |
CTD |
PMID:1868253 PMID:8548860 PMID:9118901 PMID:28836394 PMID:31256213 |
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NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
decreases cleavage multiple interactions increases expression decreases secretion |
ISO EXP |
hydroquinone results in decreased cleavage of IL1B protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of and results in increased secretion of IL1B protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of and results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of and results in increased secretion of IL1B protein]; hydroquinone results in increased expression of and results in increased secretion of IL1B protein hydroquinone results in increased expression of IL1B mRNA hydroquinone results in decreased secretion of IL1B protein [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of IL1B mRNA; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] [COL2A1 protein co-treated with Freund's Adjuvant co-treated with hydroquinone] results in increased secretion of IL1B protein; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] |
CTD |
PMID:8548860 PMID:9118901 PMID:17464197 PMID:19148301 PMID:22717997 PMID:29908986 PMID:31256213 PMID:36646296 PMID:37245849 More...
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NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1f10 |
interleukin 1 family member 10 |
increases expression |
ISO |
hydroquinone results in increased expression of IL1F10 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:27,470,798...27,473,726
Ensembl chr 3:7,072,511...7,075,439
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G |
Il1rn |
interleukin 1 receptor antagonist |
increases secretion |
ISO |
hydroquinone results in increased secretion of IL1RN protein |
CTD |
PMID:23559866 |
|
NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:7,111,550...7,127,445
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G |
Il2 |
interleukin 2 |
multiple interactions |
ISO |
hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein] |
CTD |
PMID:9571986 |
|
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566
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G |
Il23a |
interleukin 23 subunit alpha |
multiple interactions |
ISO |
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL23A mRNA] |
CTD |
PMID:17464197 |
|
NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:721,809...723,923
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G |
Il33 |
interleukin 33 |
decreases expression |
ISO |
hydroquinone results in decreased expression of IL33 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:227,721,435...227,736,373
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G |
Il36g |
interleukin 36, gamma |
increases expression |
ISO |
hydroquinone results in increased expression of IL36G mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 3:27,346,675...27,352,839
Ensembl chr 3:6,948,297...6,954,480
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G |
Il36rn |
interleukin 36 receptor antagonist |
increases expression |
ISO |
hydroquinone results in increased expression of IL36RN mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 3:27,442,679...27,449,306
Ensembl chr 3:7,044,406...7,051,016
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G |
Il4 |
interleukin 4 |
multiple interactions |
ISO |
hydroquinone promotes the reaction [keyhole-limpet hemocyanin results in increased expression of IL4 mRNA]; hydroquinone promotes the reaction [keyhole-limpet hemocyanin results in increased expression of IL4 protein] |
CTD |
PMID:12153512 |
|
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750
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G |
Il6 |
interleukin 6 |
multiple interactions decreases secretion |
EXP ISO |
[COL2A1 protein co-treated with hydroquinone] results in increased expression of IL6 protein; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] [hydroquinone co-treated with TNF protein] results in increased secretion of IL6 protein hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] hydroquinone results in decreased secretion of IL6 protein |
CTD |
PMID:17464197 PMID:19148301 PMID:20054000 PMID:22302391 PMID:22717997 PMID:23559866 PMID:29935983 PMID:34200499 More...
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NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
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G |
Inhba |
inhibin subunit beta A |
increases expression |
ISO |
hydroquinone results in increased expression of INHBA mRNA |
CTD |
PMID:31256213 |
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NCBI chr17:53,787,159...53,810,942
Ensembl chr17:49,095,920...49,108,982
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G |
Inhbe |
inhibin subunit beta E |
decreases expression |
ISO |
hydroquinone results in decreased expression of INHBE mRNA |
CTD |
PMID:29221148 |
|
NCBI chr 7:65,061,531...65,064,519
Ensembl chr 7:63,176,219...63,179,172
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G |
Inpp4b |
inositol polyphosphate-4-phosphatase type II B |
increases expression |
ISO |
hydroquinone results in increased expression of INPP4B mRNA |
CTD |
PMID:31256213 |
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NCBI chr19:42,824,710...43,575,039
Ensembl chr19:25,925,358...26,280,634
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G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of IRAK1 mRNA |
CTD |
PMID:30090394 |
|
NCBI chr X:156,919,927...156,929,825
Ensembl chr X:151,768,777...151,778,521
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G |
Irf3 |
interferon regulatory factor 3 |
multiple interactions |
ISO |
hydroquinone inhibits the reaction [AKT1 protein results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [AKT2 protein results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [AKT3 protein results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of IRF3 protein]; hydroquinone inhibits the reaction [TICAM1 protein results in increased phosphorylation of IRF3 protein] |
CTD |
PMID:28883758 |
|
NCBI chr 1:104,616,608...104,621,402
Ensembl chr 1:95,479,821...95,484,935
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G |
Irs1 |
insulin receptor substrate 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of IRS1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:83,548,944...83,606,122
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G |
Isg15 |
ISG15 ubiquitin-like modifier |
decreases expression |
ISO |
hydroquinone results in decreased expression of ISG15 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:166,784,148...166,785,435
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G |
Itgb1 |
integrin subunit beta 1 |
decreases activity decreases expression |
ISO |
hydroquinone results in decreased activity of ITGB1 protein hydroquinone results in decreased expression of ITGB1 mRNA hydroquinone results in decreased expression of ITGB1 protein |
CTD |
PMID:17464197 PMID:19148301 |
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NCBI chr19:73,602,277...73,650,271
Ensembl chr19:56,705,171...56,753,195
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G |
Itgb2 |
integrin subunit beta 2 |
decreases expression increases expression |
ISO |
hydroquinone results in decreased expression of ITGB2 protein hydroquinone results in decreased expression of ITGB2 mRNA hydroquinone results in increased expression of ITGB2 protein |
CTD |
PMID:17464197 PMID:19148301 PMID:21664406 |
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NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,061,430...11,097,600
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G |
Itgb3 |
integrin subunit beta 3 |
increases expression |
ISO |
hydroquinone results in increased expression of ITGB3 protein |
CTD |
PMID:21664406 |
|
NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679
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G |
Ivl |
involucrin |
increases expression |
ISO |
hydroquinone results in increased expression of IVL mRNA; hydroquinone results in increased expression of IVL protein |
CTD |
PMID:25240866 PMID:31256213 |
|
NCBI chr 2:180,842,307...180,854,646
Ensembl chr 2:178,147,061...178,149,100
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G |
Jag1 |
jagged canonical Notch ligand 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of JAG1 mRNA |
CTD |
PMID:22960397 |
|
NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:124,406,794...124,442,209
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G |
Jchain |
joining chain of multimeric IgA and IgM |
decreases expression |
ISO |
hydroquinone results in decreased expression of JCHAIN mRNA |
CTD |
PMID:29221148 |
|
NCBI chr14:19,822,976...19,831,072
Ensembl chr14:19,538,952...19,546,298
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G |
Jrk |
Jrk helix-turn-helix protein |
decreases expression |
ISO |
hydroquinone results in decreased expression of JRK mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 7:108,479,646...108,484,329
Ensembl chr 7:106,589,484...106,596,371
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
affects localization multiple interactions increases phosphorylation |
ISO |
hydroquinone affects the localization of JUN protein 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased phosphorylation of JUN protein]; hydroquinone promotes the reaction [JUN protein binds to MIR122 promoter]; hydroquinone promotes the reaction [JUN protein binds to PPP2CA promoter]; JUN protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 mRNA]; JUN protein affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; JUN protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; JUN protein affects the reaction [hydroquinone results in increased expression of TNF protein]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased phosphorylation of JUN protein] |
CTD |
PMID:23288922 PMID:23791922 PMID:26807887 |
|
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656
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G |
Kbtbd6 |
kelch repeat and BTB domain containing 6 |
decreases expression |
ISO |
hydroquinone results in decreased expression of KBTBD6 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr15:54,848,285...54,850,042
Ensembl chr15:54,848,446...54,850,453
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G |
Kbtbd7 |
kelch repeat and BTB domain containing 7 |
decreases expression |
ISO |
hydroquinone results in decreased expression of KBTBD7 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr15:54,806,878...54,811,457
Ensembl chr15:54,806,873...54,811,687
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G |
Kcnj15 |
potassium inwardly-rectifying channel, subfamily J, member 15 |
decreases expression |
ISO |
hydroquinone results in decreased expression of KCNJ15 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr11:48,046,953...48,091,285
Ensembl chr11:34,577,363...34,621,952
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G |
Kdm6a |
lysine demethylase 6A |
decreases expression |
ISO |
hydroquinone results in decreased expression of KDM6A mRNA |
CTD |
PMID:31256213 |
|
NCBI chr X:6,920,374...7,060,027
Ensembl chr X:4,337,750...4,477,062
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G |
Keap1 |
Kelch-like ECH-associated protein 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of KEAP1 protein |
CTD |
PMID:23290930 PMID:36646296 |
|
NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:19,768,375...19,777,862
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G |
Kics2 |
KICSTOR subunit 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of KICS2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 7:59,169,703...59,182,974
Ensembl chr 7:57,284,192...57,297,486
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G |
Kif18a |
kinesin family member 18A |
decreases expression |
ISO |
hydroquinone results in decreased expression of KIF18A mRNA |
CTD |
PMID:23416264 |
|
NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582
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G |
Kitlg |
KIT ligand |
increases expression |
ISO |
hydroquinone results in increased expression of KITLG mRNA |
CTD |
PMID:22960397 |
|
NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:34,896,053...34,977,214
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G |
Klf2 |
KLF transcription factor 2 |
increases expression |
ISO |
hydroquinone results in increased expression of KLF2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr16:17,555,136...17,557,768
Ensembl chr16:17,514,552...17,523,944
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G |
Klf4 |
KLF transcription factor 4 |
multiple interactions |
ISO |
[KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of KLF4 mRNA |
CTD |
PMID:37245849 |
|
NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:70,278,972...70,283,602
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G |
Klf7 |
KLF transcription factor 7 |
increases expression |
ISO |
hydroquinone results in increased expression of KLF7 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 9:72,927,485...73,020,167
Ensembl chr 9:65,437,167...65,526,261
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G |
Klhl31 |
kelch-like family member 31 |
decreases expression |
ISO |
hydroquinone results in decreased expression of KLHL31 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 8:78,515,514...78,538,873
Ensembl chr 8:78,515,514...78,538,873
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G |
Klk6 |
kallikrein related-peptidase 6 |
increases expression |
ISO |
hydroquinone results in increased expression of KLK6 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 1:103,415,411...103,422,682
Ensembl chr 1:94,280,340...94,286,121
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G |
Klrg2 |
killer cell lectin like receptor G2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of KLRG2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 4:67,360,216...67,374,867
Ensembl chr 4:67,363,919...67,374,147
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G |
Kmt2a |
lysine methyltransferase 2A |
decreases response to substance multiple interactions |
ISO |
KMT2A mutant form results in decreased susceptibility to hydroquinone [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of APP mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of FABP4 mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of IL1B mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of KLF4 mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of LPL mRNA; [KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of PPARG mRNA |
CTD |
PMID:37245849 |
|
NCBI chr 8:54,013,547...54,089,219
Ensembl chr 8:45,118,814...45,193,181
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G |
Kras |
KRAS proto-oncogene, GTPase |
multiple interactions increases expression affects expression |
ISO |
[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of KRAS protein hydroquinone results in increased expression of KRAS protein hydroquinone affects the expression of KRAS mRNA |
CTD |
PMID:27515134 PMID:28444915 |
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NCBI chr 4:179,916,255...179,949,613
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G |
Krt13 |
keratin 13 |
decreases expression |
ISO |
hydroquinone results in decreased expression of KRT13 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr10:85,552,287...85,556,499
Ensembl chr10:85,051,889...85,056,084
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G |
Krt19 |
keratin 19 |
decreases expression |
ISO |
hydroquinone results in decreased expression of KRT19 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr10:85,576,235...85,580,952
Ensembl chr10:85,066,802...85,171,799
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G |
Krt23 |
keratin 23 |
increases expression |
ISO |
hydroquinone results in increased expression of KRT23 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983
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G |
Krt24 |
keratin 24 |
decreases expression |
ISO |
hydroquinone results in decreased expression of KRT24 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr10:84,232,163...84,237,299
Ensembl chr10:84,232,164...84,237,299
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G |
Krt78 |
keratin 78 |
increases expression |
ISO |
hydroquinone results in increased expression of KRT78 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 7:133,074,193...133,081,536
Ensembl chr 7:133,074,215...133,082,021
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G |
Krt80 |
keratin 80 |
increases expression |
ISO |
hydroquinone results in increased expression of KRT80 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 7:132,463,216...132,485,134
Ensembl chr 7:132,463,218...132,485,508
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G |
Lama4 |
laminin subunit alpha 4 |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of LAMA4 protein [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein] |
CTD |
PMID:18055817 |
|
NCBI chr20:43,946,898...44,087,972
Ensembl chr20:42,392,268...42,533,347
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G |
Lasp1 |
LIM and SH3 protein 1 |
affects expression |
ISO |
hydroquinone affects the expression of LASP1 protein |
CTD |
PMID:20021034 |
|
NCBI chr10:83,290,820...83,331,989
Ensembl chr10:82,795,137...82,943,292
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G |
Lcn2 |
lipocalin 2 |
increases expression |
ISO |
hydroquinone results in increased expression of LCN2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:15,680,687...15,684,095
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G |
Lef1 |
lymphoid enhancer binding factor 1 |
multiple interactions decreases expression |
ISO |
hydroquinone inhibits the reaction [CTNNB1 protein binds to LEF1 protein] hydroquinone results in decreased expression of LEF1 protein |
CTD |
PMID:28886972 |
|
NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:219,666,592...219,779,794
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G |
Lemd1 |
LEM domain containing 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of LEMD1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr13:43,631,705...43,697,765
Ensembl chr13:43,665,926...43,697,948
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|
G |
Lgals9 |
galectin 9 |
increases expression |
ISO |
hydroquinone results in increased expression of LGALS9 mRNA |
CTD |
PMID:29221148 |
|
NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045
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G |
Lgalsl |
galectin-like |
increases expression |
ISO |
hydroquinone results in increased expression of LGALSL mRNA |
CTD |
PMID:31256213 |
|
NCBI chr14:94,996,991...95,004,499
Ensembl chr14:94,996,990...95,004,980
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|
G |
Lgr4 |
leucine-rich repeat-containing G protein-coupled receptor 4 |
decreases expression |
ISO |
hydroquinone results in decreased expression of LGR4 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 3:116,901,968...117,004,584
Ensembl chr 3:96,447,858...96,548,899
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G |
Lipg |
lipase G, endothelial type |
increases expression |
ISO |
hydroquinone results in increased expression of LIPG mRNA |
CTD |
PMID:31256213 |
|
NCBI chr18:70,790,077...70,811,259
Ensembl chr18:68,514,923...68,536,260
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G |
Lmna |
lamin A/C |
affects expression |
ISO |
hydroquinone affects the expression of LMNA protein |
CTD |
PMID:17181942 |
|
NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:173,939,751...173,960,423
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G |
Loricrin |
loricrin cornified envelope precursor protein |
increases expression |
ISO |
hydroquinone results in increased expression of LORICRIN mRNA hydroquinone results in increased expression of LORICRIN protein |
CTD |
PMID:25240866 PMID:31256213 |
|
NCBI chr 2:180,253,674...180,256,572
Ensembl chr 2:177,558,252...177,559,807
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G |
Lpl |
lipoprotein lipase |
multiple interactions |
ISO |
[KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of LPL mRNA |
CTD |
PMID:37245849 |
|
NCBI chr16:25,596,205...25,621,928
Ensembl chr16:20,829,465...20,855,249
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G |
Lrrc27 |
leucine rich repeat containing 27 |
decreases expression |
ISO |
hydroquinone results in decreased expression of LRRC27 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 1:194,004,967...194,035,087
Ensembl chr 1:194,005,182...194,035,084
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G |
Lrrc71 |
leucine rich repeat containing 71 |
increases expression |
ISO |
hydroquinone results in increased expression of LRRC71 mRNA |
CTD |
PMID:29221148 |
|
NCBI chr 2:173,194,792...173,207,448
Ensembl chr 2:173,194,792...173,207,448
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G |
Lrriq3 |
leucine-rich repeats and IQ motif containing 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of LRRIQ3 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 2:246,778,759...246,871,284
Ensembl chr 2:244,126,200...244,212,339
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G |
Lss |
lanosterol synthase |
decreases expression |
ISO |
hydroquinone results in decreased expression of LSS mRNA |
CTD |
PMID:31256213 |
|
NCBI chr20:12,090,641...12,118,230
Ensembl chr20:12,092,774...12,118,762
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G |
Ly6e |
lymphocyte antigen 6 family member E |
decreases expression |
ISO |
hydroquinone results in decreased expression of LY6E mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 7:108,815,970...108,820,444
Ensembl chr 7:106,935,761...106,939,689
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G |
Ly96 |
lymphocyte antigen 96 |
increases expression |
ISO |
hydroquinone results in increased expression of LY96 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 5:7,365,536...7,397,864
Ensembl chr 5:2,582,254...2,612,386
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G |
Lypd5 |
Ly6/Plaur domain containing 5 |
increases expression |
ISO |
hydroquinone results in increased expression of LYPD5 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 1:79,929,818...79,941,791
Ensembl chr 1:79,935,240...79,941,039
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G |
Macroh2a1 |
macroH2A.1 histone |
decreases expression |
ISO |
hydroquinone results in decreased expression of MACROH2A1 protein |
CTD |
PMID:35698848 |
|
NCBI chr17:8,484,340...8,547,268
Ensembl chr17:8,479,372...8,542,072
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G |
Maff |
MAF bZIP transcription factor F |
increases expression |
ISO |
hydroquinone results in increased expression of MAFF mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:110,912,499...110,923,851
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G |
Magi1 |
membrane associated guanylate kinase, WW and PDZ domain containing 1 |
multiple interactions |
ISO |
[hydroquinone co-treated with Hemin] affects the expression of MAGI1 mRNA; [hydroquinone co-treated with Hemin] affects the expression of MAGI1 protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein] |
CTD |
PMID:32198055 |
|
NCBI chr 4:127,762,590...128,368,228
Ensembl chr 4:126,206,816...126,811,691
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G |
Map1b |
microtubule-associated protein 1B |
increases expression |
ISO |
hydroquinone results in increased expression of MAP1B mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
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G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
multiple interactions |
ISO |
Chloroquine inhibits the reaction [hydroquinone results in increased degradation of MAP1LC3A protein]; hydroquinone affects the localization of and results in increased degradation of MAP1LC3A protein |
CTD |
PMID:35302183 |
|
NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:143,783,024...143,784,670
|
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
increases lipidation multiple interactions |
ISO |
hydroquinone results in increased lipidation of MAP1LC3B protein 4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; ATF6 protein affects the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; Chloroquine promotes the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; Sirolimus promotes the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein] |
CTD |
PMID:37148176 |
|
NCBI chr19:66,571,631...66,582,270
Ensembl chr19:49,665,791...49,677,690 Ensembl chr16:49,665,791...49,677,690
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|
G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
multiple interactions |
ISO |
MAP2K1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK1 protein]; MAP2K1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK3 protein]; MAP2K1 protein inhibits the reaction [hydroquinone results in increased expression of PPP2CA protein] |
CTD |
PMID:23288922 |
|
NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:64,683,449...64,755,147
|
|
G |
Map7d2 |
MAP7 domain containing 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of MAP7D2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr X:35,372,453...35,488,073
Ensembl chr X:35,372,700...35,488,091
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation decreases phosphorylation |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK1 protein]; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in decreased phosphorylation of MAPK1 protein; hydroquinone results in increased phosphorylation of and results in increased activity of MAPK1 protein; MAP2K1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK1 protein] hydroquinone results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:15129224 PMID:23288922 PMID:23290930 PMID:23791922 PMID:35561756 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
|
|
G |
Mapk14 |
mitogen activated protein kinase 14 |
multiple interactions increases phosphorylation |
ISO |
Chloroquine inhibits the reaction [hydroquinone results in increased phosphorylation of MAPK14 protein] |
CTD |
PMID:35302183 |
|
NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,749,670...6,810,589
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation decreases phosphorylation |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [hydroquinone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK3 protein]; [CSF2 protein co-treated with hydroquinone] results in increased phosphorylation of and results in increased activity of MAPK3 protein; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in decreased phosphorylation of MAPK3 protein; hydroquinone results in increased phosphorylation of and results in increased activity of MAPK3 protein; MAP2K1 protein inhibits the reaction [hydroquinone results in decreased phosphorylation of MAPK3 protein] hydroquinone results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:15129224 PMID:23288922 PMID:23290930 PMID:23791922 PMID:35561756 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
increases phosphorylation multiple interactions |
ISO |
hydroquinone results in increased phosphorylation of MAPK8 protein hydroquinone results in decreased expression of and results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:23791922 PMID:37148176 |
|
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981
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G |
Marchf3 |
membrane associated ring-CH-type finger 3 |
increases expression |
ISO |
hydroquinone results in increased expression of MARCHF3 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr18:50,237,218...50,389,343
Ensembl chr18:50,237,230...50,389,150
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|
G |
Mbd2 |
methyl-CpG binding domain protein 2 |
decreases expression multiple interactions increases expression |
ISO |
hydroquinone results in decreased expression of MBD2 mRNA PARP1 protein affects the reaction [hydroquinone results in increased expression of MBD2 protein] |
CTD |
PMID:22245671 PMID:30448557 |
|
NCBI chr18:66,449,196...66,516,112
Ensembl chr18:64,174,002...64,240,794
|
|
G |
Mbnl3 |
muscleblind-like splicing regulator 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of MBNL3 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr X:130,641,942...130,737,179
Ensembl chr X:130,648,538...130,737,056
|
|
G |
Mboat2 |
membrane bound O-acyltransferase domain containing 2 |
increases expression |
ISO |
hydroquinone results in increased expression of MBOAT2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 6:47,199,751...47,326,215
Ensembl chr 6:41,471,161...41,593,485
|
|
G |
Mc1r |
melanocortin 1 receptor |
decreases expression |
ISO |
hydroquinone results in decreased expression of MC1R mRNA |
CTD |
PMID:23738040 |
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NCBI chr19:68,360,950...68,363,877
Ensembl chr19:51,453,239...51,454,192
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G |
Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of MCL1 protein 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]; [hydroquinone co-treated with WEHI-539] results in decreased expression of MCL1 protein; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein; PMAIP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]; SP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein] |
CTD |
PMID:35561756 |
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NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:183,219,220...183,222,303
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G |
Mctp1 |
multiple C2 and transmembrane domain containing 1 |
increases expression |
ISO |
hydroquinone results in increased expression of MCTP1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:7,798,968...8,493,596
Ensembl chr 2:6,065,808...6,761,833
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G |
Mctp2 |
multiple C2 and transmembrane domain containing 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of MCTP2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:125,769,932...126,002,886
Ensembl chr 1:125,771,233...126,002,928
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G |
Mdm2 |
MDM2 proto-oncogene |
increases expression |
ISO |
hydroquinone results in increased expression of MDM2 mRNA |
CTD |
PMID:29221148 |
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NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:53,290,664...53,314,915
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G |
Mettl21a |
methyltransferase 21A, HSPA lysine |
decreases expression |
ISO |
hydroquinone results in decreased expression of METTL21A mRNA |
CTD |
PMID:31256213 |
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NCBI chr 9:73,400,223...73,484,677
Ensembl chr 9:65,978,051...65,987,550
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G |
Mgst1 |
microsomal glutathione S-transferase 1 |
increases expression |
ISO |
hydroquinone results in increased expression of MGST1 mRNA |
CTD |
PMID:15452088 |
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NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:171,029,630...171,044,892
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G |
Mid1 |
midline 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of MID1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr X:27,678,248...28,053,049
Ensembl chr X:24,120,293...24,248,353
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G |
Mir106b |
microRNA 106b |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIR106B mRNA |
CTD |
PMID:28733890 |
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NCBI chr12:22,157,053...22,157,134
Ensembl chr12:17,043,344...17,043,425
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G |
Mir107 |
microRNA 107 |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIR107 mRNA |
CTD |
PMID:28733890 |
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NCBI chr 1:241,750,418...241,750,504
Ensembl chr 1:232,337,767...232,337,853
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G |
Mir122 |
microRNA 122 |
multiple interactions decreases expression |
ISO |
ATF2 protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; FOS protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; hydroquinone promotes the reaction [ATF2 protein binds to MIR122 promoter]; hydroquinone promotes the reaction [FOS protein binds to MIR122 promoter]; hydroquinone promotes the reaction [JUN protein binds to MIR122 promoter]; JUN protein affects the reaction [hydroquinone results in decreased expression of MIR122 mRNA]; MIR122 mRNA affects the reaction [hydroquinone results in decreased expression of and results in increased secretion of TNF protein]; MIR122 mRNA affects the reaction [hydroquinone results in increased expression of ADAM17 protein]; MIR122 mRNA affects the reaction [hydroquinone results in increased expression of and results in increased stability of ADAM17 mRNA] |
CTD |
PMID:23791922 |
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NCBI chr18:61,028,817...61,028,901
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G |
Mir126a |
microRNA 126a |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIR126 mRNA |
CTD |
PMID:28733890 |
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NCBI chr 3:29,813,150...29,813,267
Ensembl chr 3:9,415,063...9,415,180
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G |
Mir130a |
microRNA 130a |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIR130A mRNA |
CTD |
PMID:28733890 |
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NCBI chr 3:90,229,228...90,229,315
Ensembl chr 3:69,822,542...69,822,629
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G |
Mir146a |
microRNA 146a |
affects expression multiple interactions |
ISO |
hydroquinone affects the expression of MIR146A mRNA hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MIR146A mRNA]; MIR146A mRNA affects the reaction [hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein]] |
CTD |
PMID:30090394 |
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NCBI chr10:28,349,996...28,350,090
Ensembl chr10:27,848,516...27,848,610
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G |
Mir155 |
microRNA 155 |
multiple interactions increases expression |
ISO |
Doxorubicin promotes the reaction [hydroquinone results in increased expression of MIR155 mRNA]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MIR155 mRNA]; trichostatin A promotes the reaction [hydroquinone results in increased expression of MIR155 mRNA] |
CTD |
PMID:30448557 |
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NCBI chr11:37,261,114...37,261,178
Ensembl chr11:23,774,654...23,774,718
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G |
Mir15b |
microRNA 15b |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIR15B mRNA |
CTD |
PMID:28733890 |
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NCBI chr 2:155,555,178...155,555,275
Ensembl chr 2:153,245,200...153,245,297
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G |
Mir17 |
microRNA 17 |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIR17 mRNA |
CTD |
PMID:28733890 |
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NCBI chr15:98,587,848...98,587,931
Ensembl chr15:92,180,629...92,180,712
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G |
Mir185 |
microRNA 185 |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIR185 mRNA |
CTD |
PMID:28733890 |
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NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
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G |
Mir18a |
microRNA 18a |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIR18A mRNA |
CTD |
PMID:28733890 |
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NCBI chr15:98,587,984...98,588,079
Ensembl chr15:92,180,765...92,180,860
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G |
Mir19a |
microRNA 19a |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIR19A mRNA |
CTD |
PMID:28733890 |
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NCBI chr15:98,588,131...98,588,212
Ensembl chr15:92,180,912...92,180,993
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G |
Mir20a |
microRNA 20a |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIR20A mRNA |
CTD |
PMID:28733890 |
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NCBI chr15:98,588,303...98,588,387
Ensembl chr15:92,181,084...92,181,168
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G |
Mir20b |
microRNA 20b |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIR20B mRNA |
CTD |
PMID:28733890 |
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NCBI chr X:137,343,197...137,343,268
Ensembl chr X:132,422,211...132,422,282
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G |
Mir223 |
microRNA 223 |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIR223 mRNA |
CTD |
PMID:35698848 |
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NCBI chr X:65,151,383...65,151,492
Ensembl chr X:61,141,887...61,141,996
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G |
Mir25 |
microRNA 25 |
decreases expression multiple interactions |
ISO |
hydroquinone results in decreased expression of MIR25; hydroquinone results in decreased expression of MIR25 mRNA [hydroquinone results in decreased expression of MIR25] which results in increased expression of NOX4 protein; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of MIR25] |
CTD |
PMID:28733890 PMID:35302183 |
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NCBI chr12:17,042,932...17,043,015
Ensembl chr12:17,042,932...17,043,015
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G |
Mir29a |
microRNA 29a |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIR29A mRNA |
CTD |
PMID:28733890 |
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NCBI chr 4:60,617,955...60,618,042
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G |
Mir342 |
microRNA 342 |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIR342 mRNA |
CTD |
PMID:28733890 |
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NCBI chr 6:133,329,655...133,329,753
Ensembl chr 6:127,565,269...127,565,367
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G |
Mir451a |
microRNA 451a |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of MIR451A mRNA hydroquinone affects the reaction [Hemin results in increased expression of MIR451A mRNA] |
CTD |
PMID:28733890 |
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NCBI chr10:63,459,569...63,459,640
Ensembl chr10:62,961,520...62,961,591
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G |
Mir486 |
microRNA 486 |
multiple interactions |
ISO |
hydroquinone affects the reaction [[Hemin co-treated with MIR486-1 mRNA] affects the expression of RASSF5 mRNA]; hydroquinone inhibits the reaction [Hemin results in increased expression of MIR486-1 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein] |
CTD |
PMID:32198055 |
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G |
Mir494 |
microRNA 494 |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIR494 mRNA |
CTD |
PMID:28733890 |
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NCBI chr 6:134,550,115...134,550,197
Ensembl chr 6:128,728,709...128,728,793
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G |
Mir8 |
microRNA 8 |
decreases expression multiple interactions |
ISO |
hydroquinone results in decreased expression of MIR7-2 hydroquinone inhibits the reaction [MIR7-2 binds to RB1 protein]; MIR7-2 inhibits the reaction [hydroquinone results in increased expression of MMP9 protein]; MIR7-2 inhibits the reaction [hydroquinone results in increased expression of RB1 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased expression of CCND1 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased expression of CCNE1 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased expression of CDK2 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased expression of CDK4 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased expression of E2F1 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased phosphorylation of RB1 protein] |
CTD |
PMID:37951342 |
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NCBI chr 1:132,806,420...132,806,514
Ensembl chr 1:132,806,420...132,806,514
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G |
Mir93 |
microRNA 93 |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIR93 mRNA |
CTD |
PMID:28733890 |
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NCBI chr12:22,156,844...22,156,930
Ensembl chr12:17,043,135...17,043,221
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G |
Mirlet7g |
microRNA let-7g |
decreases expression |
ISO |
hydroquinone results in decreased expression of MIRLET7G mRNA |
CTD |
PMID:28733890 |
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NCBI chr 8:115,701,020...115,701,107
Ensembl chr 8:106,822,280...106,822,388
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G |
Mmp1 |
matrix metallopeptidase 1 |
increases expression |
ISO |
hydroquinone results in increased expression of MMP1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:4,658,588...4,679,097
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G |
Mmp14 |
matrix metallopeptidase 14 |
multiple interactions |
ISO |
[MMP14 protein co-treated with TIMP2 protein] inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; [TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein]; MMP14 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL4A1 protein]; MMP14 protein inhibits the reaction [hydroquinone results in increased expression of LAMA4 protein] |
CTD |
PMID:18055817 |
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NCBI chr15:31,857,824...31,867,049
Ensembl chr15:27,887,727...27,899,864
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G |
Mmp15 |
matrix metallopeptidase 15 |
affects expression |
ISO |
hydroquinone affects the expression of MMP15 mRNA |
CTD |
PMID:15452088 |
|
NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943
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G |
Mmp2 |
matrix metallopeptidase 2 |
decreases activity multiple interactions |
ISO |
hydroquinone results in decreased activity of MMP2 protein [MMP14 protein co-treated with TIMP2 protein] inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; MMP14 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein]; TIMP2 protein inhibits the reaction [hydroquinone results in decreased activity of MMP2 protein] |
CTD |
PMID:16936130 PMID:18055817 |
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NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp3 |
matrix metallopeptidase 3 |
affects expression increases expression |
ISO |
hydroquinone affects the expression of MMP3 mRNA hydroquinone results in increased expression of MMP3 mRNA |
CTD |
PMID:15452088 PMID:31256213 |
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NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:4,640,416...4,653,961
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions increases expression increases secretion |
ISO |
CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; CDKN2A protein affects the reaction [hydroquinone results in increased expression of MMP9 protein]; hydroquinone inhibits the reaction [Dicumarol inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]]; hydroquinone promotes the reaction [TNF protein results in increased secretion of MMP9 protein]; MIR7-2 inhibits the reaction [hydroquinone results in increased expression of MMP9 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; PARP1 protein inhibits the reaction [hydroquinone results in increased expression of MMP9 protein]; pyrazolanthrone inhibits the reaction [hydroquinone results in increased secretion of MMP9 protein]; SB 203580 inhibits the reaction [hydroquinone results in increased secretion of MMP9 protein] hydroquinone results in increased expression of MMP9 mRNA; hydroquinone results in increased expression of MMP9 protein |
CTD |
PMID:17669387 PMID:26807887 PMID:27515134 PMID:33771647 PMID:33932074 PMID:37951342 More...
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NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120
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G |
Mob3b |
MOB kinase activator 3B |
decreases expression |
ISO |
hydroquinone results in decreased expression of MOB3B mRNA |
CTD |
PMID:31256213 |
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NCBI chr 5:54,342,509...54,534,164
Ensembl chr 5:49,545,815...49,737,934
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G |
Mpl |
MPL proto-oncogene, thrombopoietin receptor |
multiple interactions decreases methylation increases expression |
ISO |
[trichostatin A co-treated with Decitabine] promotes the reaction [hydroquinone results in increased expression of MPL mRNA]; Decitabine promotes the reaction [hydroquinone results in increased expression of MPL mRNA] hydroquinone results in decreased methylation of MPL gene |
CTD |
PMID:22245671 |
|
NCBI chr 5:137,259,288...137,281,540
Ensembl chr 5:131,973,895...131,986,797
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G |
Mpo |
myeloperoxidase |
multiple interactions increases chemical synthesis increases oxidation |
ISO |
[[[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone] which results in decreased activity of PTPN2 protein; [[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone; [MPO protein co-treated with Hydrogen Peroxide] promotes the reaction [hydroquinone results in decreased activity of TOP2A protein]; [MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone; [MPO protein results in increased hydroxylation of Phenol] which results in increased chemical synthesis of hydroquinone; MPO protein affects the reaction [hydroquinone results in increased cleavage of CASP8 protein] MPO protein results in increased chemical synthesis of hydroquinone MPO protein results in increased oxidation of hydroquinone |
CTD |
PMID:1666626 PMID:10994872 PMID:15777082 PMID:15935818 PMID:31248982 |
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NCBI chr10:73,092,124...73,102,057
Ensembl chr10:72,594,661...72,604,819
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G |
Mpzl3 |
myelin protein zero-like 3 |
increases expression |
ISO |
hydroquinone results in increased expression of MPZL3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 8:45,360,475...45,380,662
Ensembl chr 8:45,349,054...45,380,662
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G |
Mroh5 |
maestro heat-like repeat family member 5 |
decreases expression |
ISO |
hydroquinone results in decreased expression of MROH5 mRNA |
CTD |
PMID:29221148 |
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NCBI chr 7:105,662,737...105,737,820
Ensembl chr 7:105,662,744...105,730,060
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G |
Mt-co1 |
mitochondrially encoded cytochrome c oxidase I |
increases expression |
ISO |
hydroquinone results in increased expression of COX1 mRNA; hydroquinone results in increased expression of COX1 protein |
CTD |
PMID:23738040 |
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Ensembl chr MT:5,323...6,867
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G |
Mt1 |
metallothionein 1 |
increases expression |
ISO |
hydroquinone results in increased expression of MT1 mRNA |
CTD |
PMID:14998373 |
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NCBI chr19:10,831,959...10,832,975
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049 Ensembl chr X:10,826,032...10,827,049
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G |
Mt2 |
metallothionein 2 |
multiple interactions increases expression |
EXP |
[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in increased expression of MT2A mRNA; Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of MT2A mRNA] |
CTD |
PMID:33188856 |
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NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,832,002...10,832,784
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G |
Mthfd1 |
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of MTHFD1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 6:100,713,510...100,781,013
Ensembl chr 6:94,977,862...95,045,372
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G |
Mtor |
mechanistic target of rapamycin kinase |
decreases phosphorylation multiple interactions |
ISO |
hydroquinone results in decreased phosphorylation of MTOR protein 4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine inhibits the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; ATF6 protein affects the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; Sirolimus promotes the reaction [hydroquinone results in decreased phosphorylation of MTOR protein] |
CTD |
PMID:37148176 |
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NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311
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G |
Mtus1 |
microtubule associated scaffold protein 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of MTUS1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr16:57,905,991...58,051,466
Ensembl chr16:51,253,562...51,347,793
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G |
Mx1 |
MX dynamin like GTPase 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of MX1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr11:50,269,056...50,294,699
Ensembl chr11:36,799,660...36,823,507
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G |
Myb |
MYB proto-oncogene, transcription factor |
decreases expression |
ISO |
hydroquinone results in decreased expression of MYB mRNA |
CTD |
PMID:22245671 |
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NCBI chr 1:17,759,309...17,793,306
Ensembl chr 1:15,939,761...15,973,057
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions decreases expression |
ISO |
hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC protein] hydroquinone results in decreased expression of MYC mRNA |
CTD |
PMID:12749906 PMID:22245671 |
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NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630
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G |
Mycl |
MYCL proto-oncogene, bHLH transcription factor |
decreases expression |
ISO |
hydroquinone results in decreased expression of MYCL mRNA |
CTD |
PMID:31256213 |
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NCBI chr 5:140,559,843...140,566,704
Ensembl chr 5:135,274,748...135,281,582
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G |
Mylip |
myosin regulatory light chain interacting protein |
decreases expression |
ISO |
hydroquinone results in decreased expression of MYLIP mRNA |
CTD |
PMID:31256213 |
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NCBI chr17:19,492,826...19,514,490
Ensembl chr17:19,286,650...19,308,295
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G |
Myo1f |
myosin IF |
decreases expression |
ISO |
hydroquinone results in decreased expression of MYO1F mRNA |
CTD |
PMID:31256213 |
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NCBI chr 7:15,065,530...15,116,087
Ensembl chr 7:14,363,350...14,413,911
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G |
N4bp2l1 |
NEDD4 binding protein 2-like 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of N4BP2L1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr12:4,938,199...4,965,003
Ensembl chr12:102,573...127,257
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G |
Ncf2 |
neutrophil cytosolic factor 2 |
increases expression |
ISO |
hydroquinone results in increased expression of NCF2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr13:67,505,492...67,536,015
Ensembl chr13:64,955,503...64,986,277
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G |
Nedd4l |
NEDD4 like E3 ubiquitin protein ligase |
decreases expression |
ISO |
hydroquinone results in decreased expression of NEDD4L mRNA |
CTD |
PMID:31256213 |
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NCBI chr18:60,663,918...60,996,824
Ensembl chr18:58,393,509...58,723,137
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G |
Nefh |
neurofilament heavy chain |
decreases expression |
ISO |
hydroquinone results in decreased expression of NEFH mRNA |
CTD |
PMID:31256213 |
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NCBI chr14:84,044,428...84,054,413
Ensembl chr14:79,830,362...79,840,351
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G |
Neu3 |
neuraminidase 3 |
increases expression |
ISO |
hydroquinone results in increased expression of NEU3 mRNA |
CTD |
PMID:23776099 |
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NCBI chr 1:163,549,834...163,560,997
Ensembl chr 1:154,050,855...154,148,813
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G |
Neurl1b |
neuralized E3 ubiquitin protein ligase 1B |
increases expression |
ISO |
hydroquinone results in increased expression of NEURL1B mRNA |
CTD |
PMID:29221148 |
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NCBI chr10:16,754,002...16,785,049
Ensembl chr10:16,757,208...16,785,119
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G |
Nfatc2 |
nuclear factor of activated T-cells 2 |
increases expression |
ISO |
hydroquinone results in increased expression of NFATC2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:177,615,189...177,747,493
Ensembl chr 3:157,198,872...157,328,325
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G |
Nfe2 |
nuclear factor, erythroid 2 |
multiple interactions |
ISO |
hydroquinone inhibits the reaction [Hemin results in increased expression of NFE2 mRNA] |
CTD |
PMID:21414390 |
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NCBI chr 7:136,261,234...136,273,850
Ensembl chr 7:134,382,761...134,390,108
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases expression decreases expression increases activity |
ISO |
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of and affects the localization of NFE2L2 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [hydroquinone results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of NFE2L2 promoter]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of NFE2L2 protein]; ferric chloride promotes the reaction [hydroquinone results in increased expression of NFE2L2 protein]; hydroquinone affects the localization of and results in increased degradation of NFE2L2 protein; hydroquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; hydroquinone promotes the reaction [NFE2L2 protein binds to SRC protein]; hydroquinone results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of GSS protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]; S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of NFE2L2 protein] hydroquinone results in increased expression of NFE2L2 mRNA; hydroquinone results in increased expression of NFE2L2 protein hydroquinone results in decreased expression of NFE2L2 mRNA |
CTD |
PMID:21059386 PMID:21643505 PMID:23290930 PMID:28645578 PMID:31967339 PMID:32141582 PMID:35123993 PMID:36646296 More...
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NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions decreases expression increases expression |
ISO |
hydroquinone results in decreased activity of [NFKB1 protein binds to RELA protein] hydroquinone results in decreased expression of NFKB1 mRNA hydroquinone results in increased expression of NFKB1 protein |
CTD |
PMID:15894107 PMID:30090394 PMID:30448557 |
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NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkb2 |
nuclear factor kappa B subunit 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of NFKB2 mRNA |
CTD |
PMID:30090394 |
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NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:245,165,950...245,173,213
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions affects phosphorylation |
ISO |
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] hydroquinone affects the phosphorylation of NFKBIA protein hydroquinone inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:20054000 PMID:23288922 PMID:30090394 |
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NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfkbib |
NFKB inhibitor beta |
decreases degradation |
ISO |
hydroquinone results in decreased degradation of NFKBIB protein |
CTD |
PMID:15894107 |
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NCBI chr 1:93,173,817...93,181,387
Ensembl chr 1:84,046,295...84,053,862
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G |
Niban1 |
niban apoptosis regulator 1 |
increases expression |
ISO |
hydroquinone results in increased expression of NIBAN1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr13:66,224,219...66,377,728
Ensembl chr13:63,674,171...63,827,729
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G |
Nid1 |
nidogen 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of NID1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr17:93,069,013...93,142,416
Ensembl chr17:86,085,077...86,158,267
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G |
Nipal3 |
NIPA-like domain containing 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of NIPAL3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 5:152,970,934...153,010,006
Ensembl chr 5:147,685,288...147,726,351
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of NLRP3 protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of NLRP3 protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of NLRP3 protein] |
CTD |
PMID:36646296 |
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NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,328,566...44,352,811
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases expression decreases expression |
ISO |
hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; hydroquinone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] hydroquinone results in increased expression of NOS2 mRNA hydroquinone results in decreased expression of NOS2 mRNA; hydroquinone results in decreased expression of NOS2 protein |
CTD |
PMID:15831208 PMID:17464197 PMID:19148301 PMID:23290930 |
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NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210
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G |
Nox4 |
NADPH oxidase 4 |
multiple interactions increases expression |
ISO |
[[NOX4 protein results in decreased expression of ELAVL2 protein] which promotes the reaction SIDT2 protein] promotes the reaction [hydroquinone results in decreased degradation of SIRT3 protein]; [hydroquinone co-treated with WEHI-539] results in increased expression of NOX4 protein; [hydroquinone results in decreased expression of MIR25] which results in increased expression of NOX4 protein; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in increased expression of NOX4 mRNA; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in increased expression of NOX4 protein; [WEHI-539 co-treated with hydroquinone] results in increased expression of NOX4 mRNA; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 protein]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 protein]; NOX4 protein promotes the reaction [hydroquinone results in increased degradation of CASP3 protein]; NOX4 protein promotes the reaction [hydroquinone results in increased degradation of PARP1 protein]; SIDT2 protein promotes the reaction [hydroquinone results in increased expression of NOX4 mRNA] hydroquinone results in increased expression of NOX4 mRNA; hydroquinone results in increased expression of NOX4 protein |
CTD |
PMID:35302183 PMID:35561756 |
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NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:140,901,097...141,077,406
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression multiple interactions decreases response to substance |
ISO |
hydroquinone results in increased expression of NQO1 mRNA; hydroquinone results in increased expression of NQO1 protein FAU protein affects the reaction [hydroquinone results in increased expression of and results in increased activity of NQO1 protein]; hydroquinone results in increased expression of and results in increased activity of NQO1 protein NQO1 protein results in decreased susceptibility to hydroquinone ferric chloride promotes the reaction [hydroquinone results in increased expression of NQO1 protein]; hydroquinone results in increased expression of and results in increased activity of NQO1 protein; NQO1 protein inhibits the reaction [CNMD protein results in increased susceptibility to hydroquinone]; NQO1 protein inhibits the reaction [hydroquinone results in increased expression of CNMD protein]; S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of NQO1 protein] |
CTD |
PMID:8652659 PMID:10368308 PMID:10393963 PMID:19525446 PMID:21059386 PMID:22687461 PMID:23290930 PMID:28645578 PMID:29508652 PMID:30547568 PMID:31256213 PMID:32141582 PMID:36646296 More...
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NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557
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G |
Nr4a2 |
nuclear receptor subfamily 4, group A, member 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of NR4A2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:41,689,851...41,697,877
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G |
Nras |
NRAS proto-oncogene, GTPase |
decreases expression |
ISO |
hydroquinone results in decreased expression of NRAS mRNA |
CTD |
PMID:26047893 |
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NCBI chr 2:193,271,399...193,282,023
Ensembl chr 2:190,582,918...190,591,626
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G |
Nrbp2 |
nuclear receptor binding protein 2 |
increases expression |
ISO |
hydroquinone results in increased expression of NRBP2 mRNA |
CTD |
PMID:29221148 |
|
NCBI chr 7:109,679,330...109,685,656
Ensembl chr 7:107,799,497...107,805,230
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G |
Nudt16 |
nudix hydrolase 16 |
decreases expression |
ISO |
hydroquinone results in decreased expression of NUDT16 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 8:114,618,706...114,620,761
Ensembl chr 8:105,739,623...105,741,998
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G |
Nwd2 |
NACHT and WD repeat domain containing 2 |
increases expression |
ISO |
hydroquinone results in increased expression of NWD2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr14:44,480,049...44,671,417
Ensembl chr14:44,482,287...44,670,299
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G |
Oas1a |
2'-5' oligoadenylate synthetase 1A |
decreases expression |
ISO |
hydroquinone results in decreased expression of OAS1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr12:41,330,423...41,341,130
Ensembl chr12:35,669,801...35,680,517
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G |
Oas2 |
2'-5' oligoadenylate synthetase 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of OAS2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr12:41,464,568...41,492,036
Ensembl chr12:35,806,759...35,829,371
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G |
Oasl |
2'-5'-oligoadenylate synthetase-like |
increases expression |
ISO |
hydroquinone results in increased expression of OASL mRNA |
CTD |
PMID:29221148 PMID:31256213 |
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NCBI chr12:47,343,551...47,356,509
Ensembl chr12:41,682,900...41,695,641
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G |
Ocln |
occludin |
multiple interactions |
EXP |
hydroquinone results in decreased degradation of and results in increased expression of OCLN protein |
CTD |
PMID:27587462 |
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NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:31,657,220...31,764,150
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G |
Olah |
oleoyl-ACP hydrolase |
increases expression |
ISO |
hydroquinone results in increased expression of OLAH mRNA |
CTD |
PMID:31256213 |
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NCBI chr17:79,786,441...79,811,692
Ensembl chr17:74,877,655...74,902,518
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G |
Or2c1 |
olfactory receptor family 2 subfamily C member 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of OR2C1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr10:11,682,890...11,683,828
Ensembl chr10:11,681,001...11,692,105
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G |
Ovol1 |
ovo like transcriptional repressor 1 |
increases expression |
ISO |
hydroquinone results in increased expression of OVOL1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:212,284,601...212,296,106
Ensembl chr 1:202,855,265...202,866,831
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G |
P2rx4 |
purinergic receptor P2X 4 |
increases expression |
ISO |
hydroquinone results in increased expression of P2RX4 mRNA |
CTD |
PMID:31256213 |
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NCBI chr12:39,505,438...39,523,349
Ensembl chr12:33,844,396...33,862,253
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G |
Pa2g4 |
proliferation-associated 2G4 |
affects expression |
ISO |
hydroquinone affects the expression of PA2G4 protein |
CTD |
PMID:17181942 |
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NCBI chr 7:1,569,326...1,576,794
Ensembl chr 7:983,971...992,331
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G |
Pabpc4l |
poly(A) binding protein, cytoplasmic 4-like |
decreases expression |
ISO |
hydroquinone results in decreased expression of PABPC4L mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:129,807,755...129,809,745
Ensembl chr 2:129,807,755...129,809,745
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G |
Paics |
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase |
decreases expression |
ISO |
hydroquinone results in decreased expression of PAICS mRNA |
CTD |
PMID:31256213 |
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NCBI chr14:31,553,355...31,586,843
Ensembl chr14:31,173,541...31,232,635
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G |
Paip2b |
poly(A) binding protein interacting protein 2B |
decreases expression |
ISO |
hydroquinone results in decreased expression of PAIP2B mRNA |
CTD |
PMID:31256213 |
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NCBI chr 4:116,292,001...116,323,387
Ensembl chr 4:116,292,020...116,323,379
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G |
Palmd |
palmdelphin |
decreases expression |
ISO |
hydroquinone results in decreased expression of PALMD mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:207,574,413...207,626,239
Ensembl chr 2:204,889,533...204,941,519
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage increases degradation decreases expression affects response to substance increases expression increases response to substance affects expression multiple interactions |
ISO |
hydroquinone results in increased cleavage of PARP1 protein hydroquinone results in increased degradation of PARP1 protein hydroquinone results in decreased expression of PARP1 protein PARP1 protein affects the susceptibility to hydroquinone hydroquinone results in increased expression of PARP1 protein PARP1 protein results in increased susceptibility to hydroquinone hydroquinone affects the expression of PARP1 protein 3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of PARP1 protein]; [ABT-737 co-treated with hydroquinone] results in increased cleavage of PARP1 protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of and affects the activity of CASP3 protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of BCL2 protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of FAS protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of KRAS protein; [PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of TP53 protein; [PARP1 protein co-treated with hydroquinone] results in increased expression of BCL2 protein; ABT-737 inhibits the reaction [hydroquinone affects the localization of PARP1 protein]; Doxorubicin inhibits the reaction [hydroquinone results in decreased expression of PARP1 protein]; hydroquinone promotes the reaction [PARP1 protein binds to and results in increased ADP-ribosylation of and results in increased expression of HRAS protein]; hydroquinone results in increased expression of and affects the localization of PARP1 protein; hydroquinone results in increased expression of and results in increased cleavage of PARP1 protein; Lithium Chloride inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]; NOX4 protein promotes the reaction [hydroquinone results in increased degradation of PARP1 protein]; PARP1 protein affects the reaction [hydroquinone results in decreased expression of BCL2 protein]; PARP1 protein affects the reaction [hydroquinone results in decreased expression of TJP2 mRNA]; PARP1 protein affects the reaction [hydroquinone results in increased cleavage of CASP3 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of AATF protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of H2AX protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MBD2 protein]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MIR155 mRNA]; PARP1 protein affects the reaction [hydroquinone results in increased expression of MMP9 mRNA]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of BAX protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of CDKN2A protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of RB1 protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of TP53 protein]; PARP1 protein inhibits the reaction [hydroquinone results in increased expression of MMP9 protein]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of ATG5 mRNA]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of BECN1 mRNA]; PARP1 protein promotes the reaction [hydroquinone results in increased expression of HRAS protein]; WRN protein inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein] |
CTD |
PMID:19064679 PMID:23288922 PMID:26047893 PMID:26335980 PMID:26822515 PMID:28263894 PMID:28444915 PMID:28843007 PMID:28886972 PMID:28983606 PMID:29421518 PMID:30448557 PMID:33771647 PMID:35302183 More...
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NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404
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G |
Parp9 |
poly (ADP-ribose) polymerase family, member 9 |
decreases expression |
ISO |
hydroquinone results in decreased expression of PARP9 mRNA |
CTD |
PMID:31256213 |
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NCBI chr11:78,286,282...78,320,409
Ensembl chr11:64,780,981...64,815,455
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G |
Pbx1 |
PBX homeobox 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of PBX1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr13:82,811,664...83,121,447
Ensembl chr13:80,278,770...80,588,594
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G |
Pck2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
increases expression |
ISO |
hydroquinone results in increased expression of PCK2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr15:32,997,853...33,006,691
Ensembl chr15:29,027,894...29,037,283
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G |
Pdcd4 |
programmed cell death 4 |
decreases expression |
ISO |
hydroquinone results in decreased expression of PDCD4 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:252,921,392...252,944,275
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G |
Pde11a |
phosphodiesterase 11A |
decreases expression |
ISO |
hydroquinone results in decreased expression of PDE11A mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:81,320,822...81,704,397
Ensembl chr 3:60,913,562...61,297,158
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G |
Pde4b |
phosphodiesterase 4B |
decreases expression |
ISO |
hydroquinone results in decreased expression of PDE4B mRNA |
CTD |
PMID:31256213 |
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NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:116,799,971...117,367,696
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G |
Pdgfrb |
platelet derived growth factor receptor beta |
multiple interactions |
ISO |
[hydroquinone co-treated with Hemin] affects the expression of PDGFRB mRNA |
CTD |
PMID:32198055 |
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NCBI chr18:56,770,348...56,809,228
Ensembl chr18:54,499,964...54,538,843
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G |
Pdpk1 |
3-phosphoinositide dependent protein kinase-1 |
decreases activity |
ISO |
hydroquinone metabolite results in decreased activity of PDPK1 protein; hydroquinone results in decreased activity of PDPK1 protein |
CTD |
PMID:20054000 |
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NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,105,498...13,174,623
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G |
Pecam1 |
platelet and endothelial cell adhesion molecule 1 |
increases expression |
ISO |
hydroquinone results in increased expression of PECAM1 protein |
CTD |
PMID:21664406 |
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NCBI chr10:92,090,263...92,152,002
Ensembl chr10:91,590,521...91,652,116
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G |
Peg3 |
paternally expressed 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of PEG3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:76,130,965...76,157,774
Ensembl chr 1:67,097,904...67,124,671
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G |
Pgls |
6-phosphogluconolactonase |
affects expression |
ISO |
hydroquinone affects the expression of PGLS protein |
CTD |
PMID:17181942 |
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NCBI chr16:18,300,317...18,305,803
Ensembl chr16:18,300,317...18,305,803
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G |
Pglyrp4 |
peptidoglycan recognition protein 4 |
increases expression |
ISO |
hydroquinone results in increased expression of PGLYRP4 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:178,500,238...178,669,328
Ensembl chr 2:176,218,519...176,242,251
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G |
Phlda1 |
pleckstrin homology-like domain, family A, member 1 |
increases expression |
ISO |
hydroquinone results in increased expression of PHLDA1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:46,967,409...46,969,861
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G |
Pik3c3 |
phosphatidylinositol 3-kinase, catalytic subunit type 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of PIK3C3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr18:22,119,677...22,203,546
Ensembl chr18:21,845,295...21,929,048
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G |
Pik3ip1 |
phosphoinositide-3-kinase interacting protein 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of PIK3IP1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608
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G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
multiple interactions |
ISO |
Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased abundance of Reactive Oxygen Species]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein]]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased abundance of Reactive Oxygen Species]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]; PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein] |
CTD |
PMID:28836394 |
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NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:32,882,032...32,963,631
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G |
Pim1 |
Pim-1 proto-oncogene, serine/threonine kinase |
increases expression |
ISO |
hydroquinone results in increased expression of PIM1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr20:7,556,496...7,560,747
Ensembl chr20:7,554,921...7,559,174
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G |
Pitx2 |
paired-like homeodomain 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of PITX2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:220,391,417...220,411,588
Ensembl chr 2:217,717,693...217,737,293
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G |
Pkia |
cAMP-dependent protein kinase inhibitor alpha |
decreases expression |
ISO |
hydroquinone results in decreased expression of PKIA mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:96,306,181...96,380,959
Ensembl chr 2:94,398,869...94,414,282
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G |
Pkp2 |
plakophilin 2 |
increases expression |
ISO |
hydroquinone results in increased expression of PKP2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr11:98,165,974...98,231,916
Ensembl chr11:84,661,783...84,727,730
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G |
Plcxd1 |
phosphatidylinositol-specific phospholipase C, X domain containing 1 |
increases expression |
ISO |
hydroquinone results in increased expression of PLCXD1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr12:46,578,917...46,582,181
Ensembl chr12:46,579,225...46,582,392
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G |
Pld1 |
phospholipase D1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of PLD1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:112,777,820...112,975,857
Ensembl chr 2:110,893,608...111,047,692
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G |
Pllp |
plasmolipin |
decreases expression |
ISO |
hydroquinone results in decreased expression of PLLP mRNA |
CTD |
PMID:31256213 |
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NCBI chr19:10,315,104...10,335,892
Ensembl chr19:10,315,104...10,335,892
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G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
multiple interactions |
ISO |
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein]; [hydroquinone co-treated with WEHI-539] results in increased expression of PMAIP1 protein; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 mRNA; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein; BTRC protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein]; mithramycin A inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 mRNA]; mithramycin A inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein]; PMAIP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]; SP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein] |
CTD |
PMID:35561756 |
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NCBI chr18:62,255,970...62,262,384
Ensembl chr18:59,986,017...59,992,429
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G |
Pmfbp1 |
polyamine modulated factor 1 binding protein 1 |
increases expression |
ISO |
hydroquinone results in increased expression of PMFBP1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr19:54,367,562...54,417,405
Ensembl chr19:37,458,108...37,507,879
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G |
Polh |
DNA polymerase eta |
multiple interactions affects response to substance |
ISO |
POLH protein affects the reaction [hydroquinone results in increased expression of H2AX protein] POLH protein affects the susceptibility to hydroquinone |
CTD |
PMID:22981619 |
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NCBI chr 9:22,275,929...22,310,576
Ensembl chr 9:14,777,888...14,812,723
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G |
Polr1b |
RNA polymerase I subunit B |
decreases expression |
ISO |
hydroquinone results in decreased expression of POLR1B mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:136,787,130...136,811,608
Ensembl chr 3:116,333,889...116,358,379
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
increases expression |
ISO |
hydroquinone results in increased expression of PPARD mRNA |
CTD |
PMID:31256213 |
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NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
[KMT2A mutant form results in decreased susceptibility to hydroquinone] which results in increased expression of PPARG mRNA |
CTD |
PMID:37245849 |
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NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppm1d |
protein phosphatase, Mg2+/Mn2+ dependent, 1D |
increases expression |
ISO |
hydroquinone results in increased expression of PPM1D mRNA |
CTD |
PMID:23416264 |
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NCBI chr10:70,670,026...70,706,030
Ensembl chr10:70,172,603...70,208,607
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G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
increases expression |
ISO |
hydroquinone results in increased expression of PPP1R15A mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:96,000,058...96,003,171
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G |
Ppp2ca |
protein phosphatase 2 catalytic subunit alpha |
multiple interactions increases expression |
ISO |
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [hydroquinone results in increased expression of PPP2CA protein]; ATF2 protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; Chloroquine inhibits the reaction [hydroquinone results in increased expression of PPP2CA protein]; CREB1 protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; hydroquinone promotes the reaction [ATF2 protein binds to PPP2CA promoter]; hydroquinone promotes the reaction [CREB1 protein binds to PPP2CA promoter]; hydroquinone promotes the reaction [JUN protein binds to PPP2CA promoter]; JUN protein affects the reaction [hydroquinone results in increased expression of PPP2CA protein]; MAP2K1 protein inhibits the reaction [hydroquinone results in increased expression of PPP2CA protein]; PPP2CA protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2CA protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein] |
CTD |
PMID:23288922 PMID:30567741 PMID:35302183 |
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NCBI chr10:36,856,534...36,878,789
Ensembl chr10:36,358,101...36,377,862
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G |
Ppp2r5a |
protein phosphatase 2, regulatory subunit B', alpha |
multiple interactions |
ISO |
PPP2R5A protein affects the reaction [hydroquinone affects the localization of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 mRNA]; PPP2R5A protein affects the reaction [hydroquinone results in increased expression of CYP2E1 protein] |
CTD |
PMID:30567741 |
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NCBI chr13:105,462,371...105,506,767
Ensembl chr13:102,931,264...102,975,661
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G |
Pptc7 |
protein phosphatase targeting COQ7 |
decreases expression |
ISO |
hydroquinone results in decreased expression of PPTC7 mRNA |
CTD |
PMID:31256213 |
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NCBI chr12:39,910,728...39,949,101
Ensembl chr12:34,249,977...34,288,339
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G |
Prdm1 |
PR/SET domain 1 |
increases expression |
ISO |
hydroquinone results in increased expression of PRDM1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr20:49,542,465...49,564,088
Ensembl chr20:47,959,858...47,981,488
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G |
Prdx1 |
peroxiredoxin 1 |
increases expression |
ISO |
hydroquinone results in increased expression of PRDX1 mRNA |
CTD |
PMID:15452088 |
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NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:130,147,204...130,162,856
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G |
Prkcg |
protein kinase C, gamma |
affects localization |
ISO |
hydroquinone affects the localization of PRKCG protein |
CTD |
PMID:23290930 |
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NCBI chr 1:74,748,272...74,777,611
Ensembl chr 1:65,832,855...65,859,384
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G |
Prkdc |
protein kinase, DNA-activated, catalytic subunit |
increases expression |
ISO |
hydroquinone results in increased expression of PRKDC mRNA; hydroquinone results in increased expression of PRKDC protein |
CTD |
PMID:20036648 PMID:23940708 |
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NCBI chr11:98,544,952...98,762,499
Ensembl chr11:85,040,792...85,257,952
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G |
Prr9 |
proline rich 9 |
increases expression |
ISO |
hydroquinone results in increased expression of PRR9 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:177,599,483...177,600,849
Ensembl chr 2:177,599,483...177,600,849
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G |
Prss3 |
serine protease 3 |
increases expression |
ISO |
hydroquinone results in increased expression of PRSS3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 4:70,203,088...70,206,562
Ensembl chr 4:70,203,088...70,206,562
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G |
Psapl1 |
prosaposin-like 1 |
increases expression |
ISO |
hydroquinone results in increased expression of PSAPL1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr14:74,544,646...74,547,206
Ensembl chr14:74,544,646...74,547,206
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G |
Psrc1 |
proline and serine rich coiled-coil 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of PSRC1 mRNA |
CTD |
PMID:23416264 |
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NCBI chr 2:198,710,427...198,715,001
Ensembl chr 2:196,022,361...196,026,874
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G |
Ptgr2 |
prostaglandin reductase 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of PTGR2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 6:109,662,469...109,694,232
Ensembl chr 6:103,931,409...103,963,111
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression |
ISO |
hydroquinone results in increased expression of PTGS2 mRNA |
CTD |
PMID:23290930 PMID:31256213 |
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NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188
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G |
Ptpn2 |
protein tyrosine phosphatase, non-receptor type 2 |
multiple interactions |
ISO |
[[[MPO protein co-treated with Hydrogen Peroxide] results in increased metabolism of hydroquinone] which results in increased chemical synthesis of quinone] which results in decreased activity of PTPN2 protein |
CTD |
PMID:31248982 |
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NCBI chr18:63,498,890...63,564,571
Ensembl chr18:61,229,014...61,294,627
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G |
Pycard |
PYD and CARD domain containing |
multiple interactions increases expression |
ISO |
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of PYCARD protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of PYCARD protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of PYCARD protein] |
CTD |
PMID:36646296 |
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NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955
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G |
Pygb |
glycogen phosphorylase B |
increases expression |
ISO |
hydroquinone results in increased expression of PYGB mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:160,072,141...160,118,930
Ensembl chr 3:139,611,749...139,663,553
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G |
Qpct |
glutaminyl-peptide cyclotransferase |
increases expression |
ISO |
hydroquinone results in increased expression of QPCT mRNA |
CTD |
PMID:31256213 |
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NCBI chr 6:21,716,824...21,748,895
Ensembl chr 6:15,964,657...15,996,711
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G |
Rab30 |
RAB30, member RAS oncogene family |
decreases expression |
ISO |
hydroquinone results in decreased expression of RAB30 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:156,216,137...156,310,778
Ensembl chr 1:146,803,714...146,892,181
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G |
Rab3b |
RAB3B, member RAS oncogene family |
increases expression |
ISO |
hydroquinone results in increased expression of RAB3B mRNA |
CTD |
PMID:31256213 |
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NCBI chr 5:128,859,034...128,926,087
Ensembl chr 5:123,644,423...123,697,401
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G |
Rab7b |
Rab7b, member RAS oncogene family |
decreases expression |
ISO |
hydroquinone results in decreased expression of RAB7B mRNA |
CTD |
PMID:31256213 |
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NCBI chr13:45,673,396...45,699,798
Ensembl chr13:43,121,226...43,147,581
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G |
Rabgap1l |
RAB GTPase activating protein 1-like |
decreases expression |
ISO |
hydroquinone results in decreased expression of RABGAP1L mRNA |
CTD |
PMID:31256213 |
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NCBI chr13:74,997,542...75,593,240
Ensembl chr13:72,468,110...73,059,984
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G |
Raf1 |
Raf-1 proto-oncogene, serine/threonine kinase |
increases expression |
ISO |
hydroquinone results in increased expression of RAF1 mRNA |
CTD |
PMID:22245671 |
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NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:148,679,530...148,740,317
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G |
Rap1a |
RAP1A, member of RAS oncogene family |
multiple interactions |
ISO |
[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA; [hydroquinone co-treated with Hemin] affects the expression of RAP1A protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAP1A protein] |
CTD |
PMID:32198055 |
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NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:193,208,635...193,286,501
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G |
Rapgef2 |
Rap guanine nucleotide exchange factor 2 |
multiple interactions |
ISO |
[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA; [hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 mRNA]; MIR486-1 mRNA affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RAPGEF2 protein] |
CTD |
PMID:32198055 |
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NCBI chr 2:166,505,868...166,728,139
Ensembl chr 2:164,207,513...164,244,247
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G |
Rassf5 |
Ras association domain family member 5 |
multiple interactions |
ISO |
[hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA; [hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein; hydroquinone affects the reaction [[Hemin co-treated with MIR486-1 mRNA] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 mRNA]; MAGI1 protein affects the reaction [[hydroquinone co-treated with Hemin] affects the expression of RASSF5 protein] |
CTD |
PMID:32198055 |
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NCBI chr13:45,189,768...45,255,277
Ensembl chr13:42,637,549...42,703,024
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G |
Rb1 |
RB transcriptional corepressor 1 |
increases expression decreases expression multiple interactions |
ISO |
hydroquinone results in increased expression of RB protein; hydroquinone results in increased expression of RB1 mRNA hydroquinone results in decreased expression of RB1 mRNA; hydroquinone results in decreased expression of RB1 protein [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein; [E4F1 protein affects the susceptibility to hydroquinone] which results in decreased expression of RB1 protein modified form; CDKN2A protein affects the reaction [hydroquinone results in decreased expression of RB1 protein]; hydroquinone inhibits the reaction [MIR7-2 binds to RB1 protein]; hydroquinone results in decreased expression of and results in increased phosphorylation of RB1 protein; hydroquinone results in increased expression of and results in increased phosphorylation of RB1 protein; MIR7-2 inhibits the reaction [hydroquinone results in increased expression of RB1 protein]; MIR7-2 promotes the reaction [hydroquinone results in increased phosphorylation of RB1 protein]; PARP1 protein inhibits the reaction [hydroquinone results in decreased expression of RB1 protein] |
CTD |
PMID:26047893 PMID:30506647 PMID:33771647 PMID:33932074 PMID:37951342 |
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NCBI chr15:54,780,858...54,911,989
Ensembl chr15:48,371,296...48,502,302
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G |
Rbck1 |
RANBP2-type and C3HC4-type zinc finger containing 1 |
increases expression |
ISO |
hydroquinone results in increased expression of RBCK1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:161,249,389...161,266,321
Ensembl chr 3:140,789,080...140,806,005
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G |
Rdh12 |
retinol dehydrogenase 12 |
increases expression |
ISO |
hydroquinone results in increased expression of RDH12 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 6:98,015,465...98,028,388
Ensembl chr 6:98,015,465...98,028,388
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G |
Reck |
reversion-inducing-cysteine-rich protein with kazal motifs |
decreases expression |
ISO |
hydroquinone results in decreased expression of RECK mRNA |
CTD |
PMID:31256213 |
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NCBI chr 5:62,898,717...62,965,274
Ensembl chr 5:58,102,981...58,169,502
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G |
Recql4 |
RecQ like helicase 4 |
increases expression |
ISO |
hydroquinone results in increased expression of RECQL4 mRNA |
CTD |
PMID:15452088 |
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NCBI chr 7:110,304,092...110,311,426
Ensembl chr 7:108,423,455...108,430,619
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases phosphorylation affects localization |
ISO |
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased phosphorylation of RELA protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased phosphorylation of RELA protein]; hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of RELA protein]; hydroquinone inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein] hydroquinone affects the localization of RELA protein hydroquinone inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; hydroquinone results in decreased activity of [NFKB1 protein binds to RELA protein] |
CTD |
PMID:15894107 PMID:16928326 PMID:20054000 PMID:23288922 PMID:30090394 PMID:36646296 More...
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NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484
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G |
Reps1 |
RALBP1 associated Eps domain containing 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of REPS1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:14,517,589...14,595,404
Ensembl chr 1:12,697,747...12,775,561
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G |
Rftn1 |
raftlin lipid raft linker 1 |
increases expression |
ISO |
hydroquinone results in increased expression of RFTN1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 9:18,302,143...18,499,819
Ensembl chr 9:10,804,611...11,002,084
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G |
Rfx5 |
regulatory factor X5 |
decreases expression |
ISO |
hydroquinone results in decreased expression of RFX5 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:185,210,206...185,217,735
Ensembl chr 2:182,521,202...182,528,717
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G |
Rgs17 |
regulator of G-protein signaling 17 |
increases expression |
ISO |
hydroquinone results in increased expression of RGS17 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:42,222,248...42,324,625
Ensembl chr 1:42,227,070...42,324,609
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G |
Rhcg |
Rh family, C glycoprotein |
increases expression |
ISO |
hydroquinone results in increased expression of RHCG mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:133,531,704...133,555,902
Ensembl chr 1:133,531,716...133,555,876
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G |
Riok2 |
RIO kinase 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of RIOK2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:58,103,132...58,119,397
Ensembl chr 1:58,103,084...58,120,512
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G |
Rnase4 |
ribonuclease A family member 4 |
decreases expression |
ISO |
hydroquinone results in decreased expression of RNASE4 mRNA |
CTD |
PMID:31256213 |
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NCBI chr15:26,786,287...26,803,634
Ensembl chr15:24,312,464...24,330,117
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G |
Rnasel |
ribonuclease L |
decreases expression |
ISO |
hydroquinone results in decreased expression of RNASEL mRNA |
CTD |
PMID:31256213 |
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NCBI chr13:68,446,641...68,460,804
Ensembl chr13:65,901,459...65,908,704
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G |
Ror1 |
receptor tyrosine kinase-like orphan receptor 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of ROR1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 5:119,859,744...120,203,573
Ensembl chr 5:114,744,304...115,088,155
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G |
Rps6ka2 |
ribosomal protein S6 kinase A2 |
increases expression |
ISO |
hydroquinone results in increased expression of RPS6KA2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:55,178,988...55,454,271
Ensembl chr 1:52,631,736...52,906,739
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G |
Rptn |
repetin |
increases expression |
ISO |
hydroquinone results in increased expression of RPTN mRNA |
CTD |
PMID:25240866 PMID:31256213 |
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NCBI chr 2:179,061,768...179,066,056
Ensembl chr 2:179,060,017...179,065,910
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G |
Rrad |
RRAD, Ras related glycolysis inhibitor and calcium channel regulator |
increases expression |
ISO |
hydroquinone results in increased expression of RRAD mRNA |
CTD |
PMID:31256213 |
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NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
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G |
Rrp12 |
ribosomal RNA processing 12 |
decreases expression |
ISO |
hydroquinone results in decreased expression of RRP12 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:250,621,707...250,655,318
Ensembl chr 1:240,672,382...240,706,018
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G |
Runx2 |
RUNX family transcription factor 2 |
increases expression |
ISO |
hydroquinone results in increased expression of RUNX2 mRNA |
CTD |
PMID:22960397 |
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NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:16,167,482...16,492,167
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G |
S100a7a |
S100 calcium binding protein A7A |
decreases expression |
ISO |
hydroquinone results in decreased expression of S100A7A mRNA |
CTD |
PMID:25240866 |
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NCBI chr 2:178,448,983...178,453,424
Ensembl chr 2:176,151,288...176,156,441
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G |
S100a9 |
S100 calcium binding protein A9 |
increases expression |
ISO |
hydroquinone results in increased expression of S100A9 mRNA |
CTD |
PMID:25240866 |
|
NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:176,190,361...176,193,230
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G |
S100b |
S100 calcium binding protein B |
multiple interactions |
ISO |
hydroquinone results in increased expression of and results in increased secretion of S100B protein |
CTD |
PMID:24451020 |
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NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,881...12,394,743
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G |
Satb1 |
SATB homeobox 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SATB1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 9:4,916,958...5,010,359
Ensembl chr 9:4,680,920...4,753,251
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G |
Sbk1 |
SH3 domain binding kinase 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SBK1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:190,237,677...190,282,494
Ensembl chr 1:180,807,099...180,851,885
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G |
Scara3 |
scavenger receptor class A, member 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SCARA3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr15:44,315,422...44,348,416
Ensembl chr15:40,140,161...40,172,894
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G |
Scfd2 |
sec1 family domain containing 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SCFD2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr14:34,037,392...34,369,423
Ensembl chr14:33,683,273...34,008,213
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G |
Scg5 |
secretogranin V |
increases expression |
ISO |
hydroquinone results in increased expression of SCG5 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 3:100,544,101...100,588,558
Ensembl chr 3:100,544,099...100,588,463
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G |
Sdr9c7 |
short chain dehydrogenase/reductase family 9C, member 7 |
increases expression |
ISO |
hydroquinone results in increased expression of SDR9C7 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 7:63,703,788...63,720,325
Ensembl chr 7:63,707,071...63,721,480
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G |
Sec24d |
SEC24 homolog D, COPII coat complex component |
increases expression |
ISO |
hydroquinone results in increased expression of SEC24D mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:214,103,138...214,211,155
Ensembl chr 2:211,418,623...211,526,587
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G |
Selenop |
selenoprotein P |
decreases expression |
ISO |
hydroquinone results in decreased expression of SELENOP mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:54,225,736...54,236,022
Ensembl chr 2:52,498,339...52,508,852
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G |
Selp |
selectin P |
increases expression |
ISO |
hydroquinone results in increased expression of SELP mRNA; hydroquinone results in increased expression of SELP protein |
CTD |
PMID:34718823 |
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NCBI chr13:79,009,379...79,044,994
Ensembl chr13:76,476,295...76,511,845
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G |
Septin6 |
septin 6 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SEPTIN6 mRNA |
CTD |
PMID:31256213 |
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NCBI chr X:121,018,951...121,157,677
Ensembl chr X:116,153,255...116,230,115
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G |
Serpina12 |
serpin family A member 12 |
increases expression |
ISO |
hydroquinone results in increased expression of SERPINA12 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 6:128,717,334...128,732,049
Ensembl chr 6:122,952,552...122,967,271
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G |
Serpinb9 |
serpin family B member 9 |
increases expression |
ISO |
hydroquinone results in increased expression of SERPINB9 mRNA |
CTD |
PMID:31256213 |
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NCBI chr17:31,628,887...31,652,003
Ensembl chr17:31,420,125...31,443,230
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G |
Serpine2 |
serpin family E member 2 |
increases expression |
ISO |
hydroquinone results in increased expression of SERPINE2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:81,124,804...81,188,826
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G |
Sesn1 |
sestrin 1 |
increases expression |
ISO |
hydroquinone results in increased expression of SESN1 mRNA |
CTD |
PMID:23416264 |
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NCBI chr20:46,876,918...46,970,010
Ensembl chr20:45,294,871...45,387,697
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G |
Sesn2 |
sestrin 2 |
increases expression |
ISO |
hydroquinone results in increased expression of SESN2 mRNA |
CTD |
PMID:23416264 PMID:31256213 |
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NCBI chr 5:149,986,304...150,005,255
Ensembl chr 5:144,701,530...144,721,260
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G |
Sesn3 |
sestrin 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SESN3 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 8:19,415,307...19,470,943
Ensembl chr 8:11,133,678...11,185,842
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G |
Sfn |
stratifin |
affects methylation increases expression multiple interactions |
ISO |
hydroquinone affects the methylation of SFN promoter hydroquinone results in increased expression of SFN mRNA [hydroquinone affects the methylation of SFN promoter] which results in decreased abundance of 5-Methylcytosine; [hydroquinone affects the methylation of SFN promoter] which results in increased abundance of 5-hydroxymethylcytosine; TET1 protein affects the reaction [hydroquinone results in increased expression of SFN mRNA] |
CTD |
PMID:23940045 |
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NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:145,826,201...145,831,314
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G |
Sfrp1 |
secreted frizzled-related protein 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SFRP1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr16:75,278,325...75,316,736
Ensembl chr16:68,575,763...68,614,286
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G |
Sfta2 |
surfactant associated 2 |
increases expression |
ISO |
hydroquinone results in increased expression of SFTA2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr20:3,093,569...3,094,299
Ensembl chr20:3,093,565...3,094,299
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G |
Sgcg |
sarcoglycan, gamma |
increases expression |
ISO |
hydroquinone results in increased expression of SGCG mRNA |
CTD |
PMID:31256213 |
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NCBI chr15:39,564,920...39,611,149
Ensembl chr15:35,386,534...35,435,148
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G |
Sh3bgr |
SH3 domain binding glutamate-rich protein |
increases expression |
ISO |
hydroquinone results in increased expression of SH3BGR mRNA |
CTD |
PMID:31256213 |
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NCBI chr11:48,973,033...48,997,328
Ensembl chr11:35,503,725...35,527,853
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G |
Sh3bp2 |
SH3-domain binding protein 2 |
increases expression |
ISO |
hydroquinone results in increased expression of SH3BP2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr14:80,400,685...80,437,887
Ensembl chr14:76,176,101...76,213,251
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G |
Sh3kbp1 |
SH3 domain-containing kinase-binding protein 1 |
increases expression |
ISO |
hydroquinone results in increased expression of SH3KBP1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr X:38,686,530...39,031,658
Ensembl chr X:34,877,866...35,222,747
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G |
Sh3rf2 |
SH3 domain containing ring finger 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SH3RF2 mRNA |
CTD |
PMID:31256213 |
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NCBI chr18:34,296,753...34,397,880
Ensembl chr18:34,046,879...34,146,856
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G |
Sh3tc1 |
SH3 domain and tetratricopeptide repeats 1 |
increases expression |
ISO |
hydroquinone results in increased expression of SH3TC1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr14:75,005,691...75,050,001
Ensembl chr14:75,016,875...75,049,995
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G |
Siah1 |
siah E3 ubiquitin protein ligase 1 |
increases expression |
ISO |
hydroquinone results in increased expression of SIAH1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr19:20,378,908...20,402,512
Ensembl chr19:20,378,439...20,403,808
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G |
Sidt2 |
SID1 transmembrane family, member 2 |
increases expression multiple interactions |
ISO |
hydroquinone results in increased expression of SIDT2 protein [[NOX4 protein results in decreased expression of ELAVL2 protein] which promotes the reaction SIDT2 protein] promotes the reaction [hydroquinone results in decreased degradation of SIRT3 protein]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of ELAVL1 mRNA]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of MIR25]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; SIDT2 protein promotes the reaction [hydroquinone results in increased expression of NOX4 mRNA] |
CTD |
PMID:35302183 |
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NCBI chr 8:55,129,091...55,146,446
Ensembl chr 8:46,232,383...46,248,700
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G |
Sik1 |
salt-inducible kinase 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SIK1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr20:9,947,104...9,958,729
Ensembl chr20:9,947,396...9,958,991
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G |
Sirt1 |
sirtuin 1 |
multiple interactions affects expression affects response to substance |
ISO |
[SIRT1 protein affects the susceptibility to hydroquinone] which affects the expression of H2AX protein; SIRT1 protein affects the reaction [hydroquinone results in increased expression of CDKN1A protein]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of ATG5 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of BECN1 mRNA] hydroquinone affects the expression of SIRT1 mRNA; hydroquinone affects the expression of SIRT1 protein |
CTD |
PMID:27515134 PMID:28263894 |
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NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260
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G |
Sirt3 |
sirtuin 3 |
decreases expression multiple interactions increases degradation |
ISO |
hydroquinone results in decreased expression of SIRT3 mRNA; hydroquinone results in decreased expression of SIRT3 protein [[NOX4 protein results in decreased expression of ELAVL2 protein] which promotes the reaction SIDT2 protein] promotes the reaction [hydroquinone results in decreased degradation of SIRT3 protein]; Chloroquine inhibits the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; Chloroquine inhibits the reaction [hydroquinone results in decreased expression of SIRT3 protein]; ELAVL1 protein inhibits the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; ELAVL1 protein inhibits the reaction [hydroquinone results in decreased expression of SIRT3 protein]; ELAVL1 protein inhibits the reaction [hydroquinone results in increased degradation of SIRT3 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; NOX4 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 protein]; SIDT2 protein promotes the reaction [hydroquinone results in decreased expression of SIRT3 mRNA]; SIRT3 protein inhibits the reaction [hydroquinone results in increased expression of TNF mRNA] |
CTD |
PMID:35302183 |
|
NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:195,942,073...195,964,808
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G |
Slc16a6 |
solute carrier family 16, member 6 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SLC16A6 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr10:94,923,888...94,946,990
Ensembl chr10:94,426,244...94,448,779
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G |
Slc2a1 |
solute carrier family 2 member 1 |
increases expression |
EXP |
hydroquinone results in increased expression of SLC2A1 protein |
CTD |
PMID:27587462 |
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NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:132,717,196...132,745,416
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G |
Slc2a12 |
solute carrier family 2 member 12 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SLC2A12 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 1:24,623,558...24,683,577
Ensembl chr 1:22,804,418...22,860,971
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G |
Slc2a5 |
solute carrier family 2 member 5 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SLC2A5 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 5:165,857,412...165,892,928
Ensembl chr 5:160,583,234...160,611,106
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G |
Slc5a1 |
solute carrier family 5 member 1 |
increases expression |
ISO |
hydroquinone results in increased expression of SLC5A1 mRNA |
CTD |
PMID:31256213 |
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NCBI chr14:81,778,495...81,843,084
Ensembl chr14:77,553,843...77,618,547
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G |
Slc5a3 |
solute carrier family 5 member 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SLC5A3 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr11:44,799,787...44,802,233
Ensembl chr11:31,295,476...31,318,883
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G |
Slc7a11 |
solute carrier family 7 member 11 |
increases expression |
ISO |
hydroquinone results in increased expression of SLC7A11 mRNA |
CTD |
PMID:31256213 |
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NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:133,963,107...134,517,536
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G |
Smim5 |
small integral membrane protein 5 |
increases expression |
ISO |
hydroquinone results in increased expression of SMIM5 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr10:101,134,033...101,139,814
Ensembl chr10:101,134,033...101,139,813
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G |
Snx24 |
sorting nexin 24 |
increases expression |
ISO |
hydroquinone results in increased expression of SNX24 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr18:46,670,987...46,826,070
Ensembl chr18:46,671,443...46,826,068
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G |
Sod1 |
superoxide dismutase 1 |
decreases activity multiple interactions increases expression decreases expression |
ISO |
hydroquinone results in decreased activity of SOD1 protein S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of SOD1 protein] hydroquinone results in decreased expression of SOD1 mRNA |
CTD |
PMID:15816534 PMID:32141582 |
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NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
decreases activity multiple interactions increases expression decreases expression |
ISO |
hydroquinone results in decreased activity of SOD2 protein S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of SOD2 protein] hydroquinone results in decreased expression of SOD2 mRNA |
CTD |
PMID:15816534 PMID:32141582 |
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NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189
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G |
Sox11 |
SRY-box transcription factor 11 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SOX11 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 6:49,736,773...49,738,794
Ensembl chr 6:44,008,340...44,010,354
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G |
Sox2 |
SRY-box transcription factor 2 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SOX2 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:117,536,929...117,539,338
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G |
Sox4 |
SRY-box transcription factor 4 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SOX4 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr17:35,876,298...35,881,004
Ensembl chr17:35,667,537...35,673,665
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G |
Sp1 |
Sp1 transcription factor |
multiple interactions |
ISO |
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of SP1 protein]; [hydroquinone co-treated with WEHI-539] results in increased expression of SP1 protein; [WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of SP1 protein; BTRC protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of SP1 protein]; SP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of MCL1 protein]; SP1 protein affects the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in increased expression of PMAIP1 protein] |
CTD |
PMID:35561756 |
|
NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:133,541,491...133,571,961
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G |
Sp110 |
SP110 nuclear body protein |
decreases expression |
ISO |
hydroquinone results in decreased expression of SP110 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 9:93,648,574...93,673,476
Ensembl chr 9:86,200,503...86,222,670
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G |
Spi1 |
Spi-1 proto-oncogene |
increases phosphorylation |
ISO |
hydroquinone results in increased phosphorylation of SPI1 protein |
CTD |
PMID:16642264 |
|
NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:77,073,012...77,092,393
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G |
Spink1 |
serine peptidase inhibitor, Kazal type 1 |
increases expression |
ISO |
hydroquinone results in increased expression of SPINK1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr18:36,121,626...36,133,596
Ensembl chr18:35,824,550...35,882,642
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G |
Spink4 |
serine peptidase inhibitor, Kazal type 4 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SPINK4 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 5:56,043,936...56,064,841
Ensembl chr 5:55,981,624...56,064,795
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G |
Spink6 |
serine peptidase inhibitor, Kazal type 6 |
decreases expression |
ISO |
hydroquinone results in decreased expression of SPINK6 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr18:36,397,833...36,410,010
Ensembl chr18:36,397,910...36,409,819
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G |
Sprr2b |
small proline rich protein 2B |
increases expression |
ISO |
hydroquinone results in increased expression of SPRR2B mRNA |
CTD |
PMID:25240866 PMID:31256213 |
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NCBI chr 2:177,852,824...177,853,096
Ensembl chr 2:177,852,824...177,853,096
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G |
Sprr3 |
small proline-rich protein 3 |
increases expression |
ISO |
hydroquinone results in increased expression of SPRR3 mRNA |
CTD |
PMID:25240866 PMID:31256213 |
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NCBI chr 2:180,723,038...180,725,695
Ensembl chr 2:178,027,425...178,029,891
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G |
Spry4 |
sprouty RTK signaling antagonist 4 |
increases expression |
ISO |
hydroquinone results in increased expression of SPRY4 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr18:30,436,513...30,451,426
Ensembl chr18:30,436,443...30,453,004
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G |
Sqstm1 |
sequestosome 1 |
decreases expression multiple interactions |
ISO |
hydroquinone results in decreased expression of SQSTM1 protein 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in decreased expression of SQSTM1 protein]; [venetoclax co-treated with WEHI-539 co-treated with hydroquinone] results in decreased expression of SQSTM1 protein; Chloroquine inhibits the reaction [hydroquinone results in increased degradation of SQSTM1 protein]; hydroquinone results in increased degradation of and results in decreased expression of SQSTM1 protein |
CTD |
PMID:28263894 PMID:35302183 PMID:35561756 PMID:37148176 |
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NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673
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G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
multiple interactions increases phosphorylation |
ISO |
AG 1879 inhibits the reaction [hydroquinone results in increased phosphorylation of SRC protein] hydroquinone promotes the reaction [NFE2L2 protein binds to SRC protein] |
CTD |
PMID:23290930 |
|
NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476
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G |
St3gal3 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of ST3GAL3 mRNA |
CTD |
PMID:23776099 |
|
NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810
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G |
St6galnac5 |
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
decreases expression |
ISO |
hydroquinone results in decreased expression of ST6GALNAC5 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 2:244,398,604...244,571,100
Ensembl chr 2:241,742,688...241,911,208
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G |
Stat1 |
signal transducer and activator of transcription 1 |
decreases expression |
ISO |
hydroquinone results in decreased expression of STAT1 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:49,419,340...49,588,540
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G |
Stc2 |
stanniocalcin 2 |
increases expression |
ISO |
hydroquinone results in increased expression of STC2 mRNA |
CTD |
PMID:23416264 PMID:31256213 |
|
NCBI chr10:16,755,508...16,765,275
Ensembl chr10:16,250,853...16,262,973
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G |
Stk40 |
serine/threonine kinase 40 |
increases expression |
ISO |
hydroquinone results in increased expression of STK40 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 5:143,660,438...143,702,336
Ensembl chr 5:138,381,159...138,417,796
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G |
Stxbp6 |
syntaxin binding protein 6 |
decreases expression |
ISO |
hydroquinone results in decreased expression of STXBP6 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 6:61,920,756...62,157,405
Ensembl chr 6:61,920,756...62,158,024
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G |
Sybu |
syntabulin |
increases expression |
ISO |
hydroquinone results in increased expression of SYBU mRNA |
CTD |
PMID:31256213 |
|
NCBI chr 7:77,731,662...77,833,413
Ensembl chr 7:75,847,003...75,948,828
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G |
Sycp2l |
synaptonemal complex protein 2-like |
decreases expression |
ISO |
hydroquinone results in decreased expression of SYCP2L mRNA |
CTD |
PMID:31256213 |
|
NCBI chr17:23,589,217...23,645,273
Ensembl chr17:23,592,899...23,648,306
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G |
Taf3 |
TATA-box binding protein associated factor 3 |
decreases expression |
ISO |
hydroquinone results in decreased expression of TAF3 mRNA |
CTD |
PMID:31256213 |
|
NCBI chr17:73,365,162...73,518,053
Ensembl chr17:68,423,909...68,608,367
|
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