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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:8-Epidiosbulbin E acetate
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Accession:CHEBI:175936 term browser browse the term
Synonyms:exact_synonym: [(1R,2S,3S,5S,8S,10S,11R,13R)-8-(uran-3-yl)-10-methyl-6,15-dioxo-7,14-dioxatetracyclo[11.2.1.02,11.05,10]hexadecan-3-yl] acetate
 related_synonym: Formula=C21H24O7;   InChI=1S/C21H24O7/c1-10(22)26-16-7-15-20(24)28-17(11-3-4-25-9-11)8-21(15,2)14-6-12-5-13(18(14)16)19(23)27-12/h3-4,9,12-18H,5-8H2,1-2H3/t12-,13+,14+,15+,16-,17-,18+,21-/m0/s1;   InChIKey=DYSOIAQEKRDXRB-GFTCARDDSA-N;   SMILES=O1[C@@]2(C[C@]3([C@]4([C@](C[C@H](OC(=O)C)[C@@]3([C@@](C2)(C1=O)[H])[H])(C(O[C@@H](C4)C=5C=COC5)=O)[H])C)[H])[H]
 xref: Chemspider:95532215
 xref_mesh: MESH:C534602



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8-Epidiosbulbin E acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of ABCB11 protein CTD PMID:31626840 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of ABCC2 mRNA CTD PMID:31626840 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of ABCC3 protein CTD PMID:31626840 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Ada adenosine deaminase increases expression ISO 8-epidiosbulbin E acetate results in increased expression of ADA mRNA CTD PMID:31626840 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of BAAT mRNA CTD PMID:31626840 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 8-epidiosbulbin E acetate results in increased expression of CYP1A1 protein CTD PMID:31626840 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of CYP2E1 mRNA CTD PMID:31626840 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases metabolic processing
ISO Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of 8-epidiosbulbin E acetate] CTD PMID:26286065 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of CYP7A1 mRNA; 8-epidiosbulbin E acetate results in decreased expression of CYP7A1 protein CTD PMID:31626840 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of CYP8B1 protein CTD PMID:31626840 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Fh fumarate hydratase decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of FH1 mRNA CTD PMID:31626840 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity ISO 8-epidiosbulbin E acetate results in increased activity of GPT protein CTD PMID:31626840 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of IDH2 mRNA CTD PMID:31626840 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of SLC10A1 protein CTD PMID:31626840 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of SLCO1A4 mRNA CTD PMID:31626840 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases expression ISO 8-epidiosbulbin E acetate results in decreased expression of UGT1A1 mRNA CTD PMID:31626840 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    chemical entity 20055
      atom 20054
        nonmetal atom 19945
          oxygen atom 19666
            oxygen molecular entity 19666
              organooxygen compound 19243
                8-Epidiosbulbin E acetate 16
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19875
                          organic molecular entity 19875
                            organic molecule 19822
                              organic cyclic compound 19575
                                organic heterocyclic compound 18798
                                  organic heteropolycyclic compound 18272
                                    organic heterotricyclic compound 15596
                                      8-Epidiosbulbin E acetate 16
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