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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:linalool
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Accession:CHEBI:17580 term browser browse the term
Definition:A monoterpenoid that is octa-1,6-diene substituted by methyl groups at positions 3 and 7 and a hydroxy group at position 3. It has been isolated from plants like Ocimum canum.
Synonyms:related_synonym: 2,6-dimethylocta-2,7-dien-6-ol;   3,7-Dimethylocta-1,6-dien-3-ol;   Formula=C10H18O;   InChI=1S/C10H18O/c1-5-10(4,11)8-6-7-9(2)3/h5,7,11H,1,6,8H2,2-4H3;   InChIKey=CDOSHBSSFJOMGT-UHFFFAOYSA-N;   SMILES=CC(C)=CCCC(C)(O)C=C;   beta-linalool;   linalyl alcohol
 alt_id: CHEBI:11712;   CHEBI:1417;   CHEBI:19917
 xref: BPDB:2150;   CAS:78-70-6;   Gmelin:406448;   HMDB:HMDB0036100;   KEGG:C03985;   KNApSAcK:C00003047;   LIPID_MAPS_instance:LMPR0102010004
 xref_mesh: MESH:C018584
 xref: PMID:18695915;   PMID:24570447;   PMID:24758511;   Reaxys:1362385;   VSDB:2150;   Wikipedia:Linalool


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linalool term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACACA mRNA CTD PMID:38000518 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acacb acetyl-CoA carboxylase beta multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ACACB mRNA CTD PMID:38000518 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655 		JBrowse link
G Acly ATP citrate lyase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACLY mRNA CTD PMID:38000518 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Aco1 aconitase 1 increases expression ISO linalool results in increased expression of ACO1 mRNA CTD PMID:24752549 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391 		JBrowse link
G Aco2 aconitase 2 increases expression ISO linalool results in increased expression of ACO2 mRNA CTD PMID:24752549 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261 		JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions
increases expression		 ISO PPARA protein promotes the reaction [linalool results in increased expression of ACOX1 protein]
linalool results in increased expression of ACOX1 mRNA; linalool results in increased expression of ACOX1 protein
PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACOX1 protein]		 CTD PMID:24752549 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 multiple interactions
increases expression		 ISO PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACSL1 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACSL1 protein]
linalool results in increased expression of ACSL1 mRNA; linalool results in increased expression of ACSL1 protein
PPARA protein promotes the reaction [linalool results in increased expression of ACSL1 protein]		 CTD PMID:24752549 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACTA2 mRNA CTD PMID:38000518 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AHR mRNA CTD PMID:38000518 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO linalool results in increased expression of AKR1C2 mRNA CTD PMID:20491607 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases expression
multiple interactions		 ISO linalool results in increased expression of AKT1 mRNA
[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AKT1 mRNA		 CTD PMID:19922762 PMID:38000518 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alas2 5'-aminolevulinate synthase 2 decreases expression EXP linalool results in decreased expression of ALAS2 mRNA CTD PMID:20536181 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519 		JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit decreases expression EXP linalool results in decreased expression of APH1B mRNA CTD PMID:20536181 NCBI chr 8:67,429,198...67,454,735
Ensembl chr 8:67,429,198...67,450,243 		JBrowse link
G Apoa1 apolipoprotein A1 increases expression ISO linalool results in increased expression of APOA1 mRNA CTD PMID:24752549 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoc3 apolipoprotein C3 decreases expression ISO linalool results in decreased expression of APOC3 mRNA; linalool results in decreased expression of APOC3 protein CTD PMID:24752549 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Ar androgen receptor multiple interactions ISO linalool inhibits the reaction [Testosterone results in increased activity of AR protein] CTD PMID:31393563 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Atf2 activating transcription factor 2 increases expression ISO linalool results in increased expression of ATF2 mRNA CTD PMID:19922762 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO linalool results in increased expression of BAK1 mRNA CTD PMID:28567457 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO linalool results in increased expression of BAX mRNA CTD PMID:26703569 PMID:28567457 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO linalool results in decreased expression of BCL2 mRNA CTD PMID:28567457 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO linalool results in decreased expression of BCL2L1 mRNA CTD PMID:28567457 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO linalool results in increased expression of BIRC2 mRNA CTD PMID:19922762 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO linalool results in increased expression of BIRC3 mRNA CTD PMID:19922762 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Casp3 caspase 3 increases expression
increases activity		 ISO linalool results in increased expression of CASP3 mRNA
linalool results in increased activity of CASP3 protein		 CTD PMID:26703569 PMID:28567457 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 increases expression ISO linalool results in increased expression of CASP8 mRNA CTD PMID:26703569 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases expression
increases activity		 ISO linalool results in increased expression of CASP9 mRNA
linalool results in increased activity of CASP9 protein		 CTD PMID:26703569 PMID:28567457 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions EXP
ISO		 linalool inhibits the reaction [[Phosphates co-treated with Adenine] results in increased expression of CAT protein]; linalool inhibits the reaction [Methamphetamine results in decreased activity of CAT protein]
[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of CAT mRNA		 CTD PMID:30466616 PMID:37729970 PMID:38000518 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA CTD PMID:38000518 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Cd86 CD86 molecule increases expression ISO linalool metabolite results in increased expression of CD86 protein CTD PMID:29029310 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdh1 cadherin 1 increases expression ISO linalool results in increased expression of CDH1 mRNA CTD PMID:26703569 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO linalool results in increased expression of CDKN1A mRNA CTD PMID:19922762 PMID:26703569 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO linalool results in increased expression of CDKN1B mRNA CTD PMID:19922762 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression ISO linalool results in increased expression of CDKN1C mRNA CTD PMID:19922762 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO linalool results in increased expression of CDKN2A mRNA CTD PMID:26703569 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression ISO linalool results in increased expression of CDKN2B mRNA CTD PMID:19922762 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C increases expression ISO linalool results in increased expression of CDKN2C mRNA CTD PMID:26703569 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression EXP linalool results in increased expression of CEBPB mRNA CTD PMID:20536181 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression EXP linalool results in increased expression of CEBPD mRNA CTD PMID:20536181 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829 		JBrowse link
G Col10a1 collagen type X alpha 1 chain increases expression EXP linalool results in increased expression of COL10A1 mRNA CTD PMID:20536181 NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of COL1A1 mRNA CTD PMID:38000518 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Cp ceruloplasmin multiple interactions EXP linalool inhibits the reaction [Methamphetamine results in decreased expression of CP protein] CTD PMID:37729970 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT1A mRNA CTD PMID:38000518 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT2 mRNA CTD PMID:38000518 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095 		JBrowse link
G Csn2 casein beta increases expression ISO linalool results in increased expression of CSN2 mRNA CTD PMID:19922762 NCBI chr14:20,322,581...20,329,818
Ensembl chr14:20,322,581...20,329,817 		JBrowse link
G Ctsd cathepsin D increases expression
multiple interactions		 ISO linalool results in increased expression of CTSD mRNA
Fulvestrant inhibits the reaction [linalool results in increased expression of CTSD mRNA]		 CTD PMID:19922762 PMID:31393563 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions		 ISO linalool results in increased expression of CYP1A1 mRNA
[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CYP1A1 mRNA		 CTD PMID:20491607 PMID:38000518 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO linalool results in increased expression of CYP27A1 mRNA CTD PMID:24752549 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 multiple interactions ISO linalool inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA] CTD PMID:31393563 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of DGAT1 mRNA CTD PMID:38000518 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression ISO linalool results in increased expression of DHCR7 mRNA CTD PMID:24752549 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression EXP linalool results in increased expression of DNAJB1 mRNA CTD PMID:20536181 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 increases expression ISO linalool results in increased expression of ECHS1 mRNA CTD PMID:24752549 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Edn1 endothelin 1 increases expression ISO linalool results in increased expression of EDN1 mRNA CTD PMID:19922762 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Egfr epidermal growth factor receptor increases expression ISO linalool results in increased expression of EGFR mRNA CTD PMID:19922762 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 decreases expression ISO linalool results in decreased expression of ELOVL3 mRNA CTD PMID:24752549 NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115 		JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO linalool results in increased activity of ESR1 protein CTD PMID:31393563 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G F2 coagulation factor II, thrombin multiple interactions EXP linalool inhibits the reaction [Methamphetamine results in decreased expression of F2 protein] CTD PMID:37729970 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO linalool results in increased expression of FABP1 mRNA CTD PMID:24752549 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FASN mRNA CTD PMID:38000518 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fn1 fibronectin 1 increases expression ISO linalool results in increased expression of FN1 mRNA CTD PMID:19922762 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP linalool results in increased expression of FOS mRNA CTD PMID:20536181 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FOXO1 mRNA CTD PMID:38000518 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 increases expression EXP linalool results in increased expression of GABBR1 mRNA CTD PMID:20536181 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO linalool results in increased expression of GADD45A mRNA; linalool results in increased expression of GADD45A protein CTD PMID:19922762 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO linalool results in increased expression of GCLC mRNA CTD PMID:20491607 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GPX1 mRNA CTD PMID:38000518 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
increases expression		 ISO Fulvestrant inhibits the reaction [linalool results in increased expression of GREB1 mRNA] CTD PMID:31393563 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GSR mRNA CTD PMID:38000518 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Hbb hemoglobin subunit beta decreases expression EXP linalool results in decreased expression of HBB mRNA CTD PMID:20536181 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
decreases expression		 ISO linalool inhibits the reaction [KAT2B protein binds to HMGCR promoter]; linalool inhibits the reaction [SREBF2 protein binds to HMGCR promoter]; linalool results in decreased expression of and results in increased ubiquitination of HMGCR protein
linalool results in decreased expression of HMGCR mRNA; linalool results in decreased expression of HMGCR protein		 CTD PMID:21944868 PMID:24613879 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO linalool metabolite results in increased expression of HMOX1 mRNA CTD PMID:29029310 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Homer1 homer scaffold protein 1 increases expression EXP linalool results in increased expression of HOMER1 mRNA CTD PMID:20536181 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785 		JBrowse link
G Hsf1 heat shock transcription factor 1 increases expression ISO linalool results in increased expression of HSF1 mRNA CTD PMID:19922762 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO linalool results in increased expression of HSP90AA1 mRNA CTD PMID:19922762 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like increases expression EXP linalool results in increased expression of HSPA1L mRNA CTD PMID:20536181 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases expression ISO linalool results in increased expression of HSPA4 mRNA CTD PMID:19922762 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP linalool results in increased expression of HSPB1 mRNA CTD PMID:20536181 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Hspb2 heat shock protein family B (small) member 2 increases expression ISO linalool results in increased expression of HSPB2 mRNA CTD PMID:19922762 NCBI chr 8:51,093,267...51,094,528
Ensembl chr 8:51,081,342...51,094,533 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression EXP linalool results in increased expression of HSPH1 mRNA CTD PMID:20536181 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
multiple interactions		 ISO linalool metabolite results in increased expression of ICAM1 protein
linalool inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]		 CTD PMID:29029310 PMID:29276222 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression ISO linalool results in increased expression of ID2 mRNA CTD PMID:19922762 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Il10 interleukin 10 multiple interactions EXP linalool inhibits the reaction [Methamphetamine results in decreased expression of IL10 protein] CTD PMID:37729970 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP linalool inhibits the reaction [Methamphetamine results in increased expression of IL1B protein] CTD PMID:37729970 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP linalool inhibits the reaction [Methamphetamine results in increased expression of IL6 protein] CTD PMID:37729970 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO linalool results in increased expression of INSIG1 protein CTD PMID:21944868 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Insig2 insulin induced gene 2 increases expression ISO linalool results in increased expression of INSIG2 mRNA CTD PMID:24752549 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO linalool results in increased expression of JUN protein CTD PMID:19922762 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kat2b lysine acetyltransferase 2B multiple interactions ISO linalool inhibits the reaction [KAT2B protein binds to HMGCR promoter] CTD PMID:21944868 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Lipa lipase A, lysosomal acid type increases expression ISO linalool results in increased expression of LIPA mRNA CTD PMID:24752549 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Lpl lipoprotein lipase increases expression
multiple interactions		 ISO linalool results in increased expression of LPL mRNA; linalool results in increased expression of LPL protein
PPARA gene mutant form inhibits the reaction [linalool results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of LPL protein]
PPARA protein promotes the reaction [linalool results in increased expression of LPL protein]		 CTD PMID:24752549 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO linalool metabolite results in increased phosphorylation of MAPK1 protein CTD PMID:29029310 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO linalool metabolite results in increased phosphorylation of MAPK3 protein CTD PMID:29029310 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases expression EXP linalool results in increased expression of MARCKS mRNA CTD PMID:20536181 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012 		JBrowse link
G Mcee methylmalonyl CoA epimerase decreases expression ISO linalool results in decreased expression of MCEE mRNA CTD PMID:24752549 NCBI chr 1:117,964,576...117,987,779
Ensembl chr 1:117,964,576...117,988,484 		JBrowse link
G Mdh2 malate dehydrogenase 2 increases expression ISO linalool results in increased expression of MDH mRNA CTD PMID:24752549 NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO linalool results in increased expression of MDM2 mRNA CTD PMID:19922762 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mlycd malonyl-CoA decarboxylase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of MLYCD mRNA CTD PMID:38000518 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO linalool results in increased expression of MMP9 mRNA CTD PMID:26703569 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpz myelin protein zero decreases expression EXP linalool results in decreased expression of MPZ mRNA CTD PMID:20536181 NCBI chr13:83,570,811...83,576,680
Ensembl chr13:83,570,811...83,576,679 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO linalool results in increased expression of MYC mRNA CTD PMID:19922762 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFE2L2 mRNA; linalool metabolite results in increased expression of and results in increased activity of NFE2L2 protein CTD PMID:29029310 PMID:38000518 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression
multiple interactions		 ISO linalool results in increased expression of NFKB1 mRNA
[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFKB1 mRNA		 CTD PMID:19922762 PMID:38000518 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Npy neuropeptide Y increases expression EXP
ISO		 linalool results in increased expression of NPY mRNA
linalool results in increased expression of NPY protein		 CTD PMID:22757684 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO linalool metabolite results in increased expression of NQO1 mRNA CTD PMID:29029310 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO linalool results in increased expression of PCK2 mRNA CTD PMID:24752549 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283 		JBrowse link
G Pgm1 phosphoglucomutase 1 increases expression ISO linalool results in increased expression of PGM1 mRNA CTD PMID:24752549 NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728 		JBrowse link
G Pgr progesterone receptor multiple interactions
increases expression		 ISO Fulvestrant inhibits the reaction [linalool results in increased expression of PGR mRNA] CTD PMID:31393563 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Phf1 PHD finger protein 1 decreases expression ISO linalool results in decreased expression of PHF1 mRNA CTD PMID:27683099 NCBI chr20:5,017,765...5,022,872
Ensembl chr20:5,017,893...5,022,871 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression
increases response to substance
decreases response to substance
multiple interactions		 ISO linalool results in increased expression of PPARA mRNA; linalool results in increased expression of PPARA protein
PPARA protein results in increased susceptibility to linalool
PPARA gene mutant form results in decreased susceptibility to linalool
[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PPARA mRNA; linalool binds to and results in increased activity of PPARA protein; PPARA protein promotes the reaction [linalool results in increased expression of ACOX1 protein]; PPARA protein promotes the reaction [linalool results in increased expression of ACSL1 protein]; PPARA protein promotes the reaction [linalool results in increased expression of LPL protein]; PPARA protein promotes the reaction [linalool results in increased expression of SLC27A4 protein]; PPARA protein promotes the reaction [linalool results in increased expression of UCP2 protein]
PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACOX1 protein]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACSL1 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of ACSL1 protein]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of LPL protein]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of SLC27A4 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of SLC27A4 protein]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of UCP2 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of UCP2 protein]		 CTD PMID:24752549 PMID:38000518 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Psmd9 proteasome 26S subunit, non-ATPase 9 increases expression ISO linalool results in increased expression of PSMD9 mRNA CTD PMID:26703569 NCBI chr12:33,337,182...33,357,468 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PTGS1 mRNA CTD PMID:38000518 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Pxmp4 peroxisomal membrane protein 4 decreases expression EXP linalool results in decreased expression of PXMP4 mRNA CTD PMID:20536181 NCBI chr 3:143,093,371...143,110,620
Ensembl chr 3:143,093,018...143,110,651 		JBrowse link
G Rgs5 regulator of G-protein signaling 5 increases expression EXP linalool results in increased expression of RGS5 mRNA CTD PMID:20536181 NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518 		JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions EXP linalool inhibits the reaction [[Phosphates co-treated with Adenine] results in increased expression of RUNX2 mRNA] CTD PMID:30466616 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Rusf1 RUS family member 1 increases expression EXP linalool results in increased expression of RUSF1 mRNA CTD PMID:20536181 NCBI chr 1:182,852,257...182,881,652
Ensembl chr 1:182,852,262...182,880,732 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 decreases expression ISO linalool results in decreased expression of RUVBL2 mRNA CTD PMID:27683099 NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342 		JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression EXP linalool results in decreased expression of S100A9 mRNA CTD PMID:20536181 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO linalool inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788 		JBrowse link
G Sele selectin E multiple interactions ISO linalool inhibits the reaction [TNF protein results in increased expression of SELE mRNA] CTD PMID:29276222 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Sirt3 sirtuin 3 decreases expression
multiple interactions		 ISO linalool results in decreased expression of SIRT3 mRNA; linalool results in decreased expression of SIRT3 protein
linalool inhibits the reaction [SOD2 protein binds to SIRT3 protein]		 CTD PMID:28567457 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Slc20a1 solute carrier family 20 member 1 multiple interactions EXP linalool inhibits the reaction [[Phosphates co-treated with Adenine] results in increased expression of SLC20A1 mRNA] CTD PMID:30466616 NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051 		JBrowse link
G Slc27a4 solute carrier family 27 member 4 multiple interactions
increases expression		 ISO PPARA gene mutant form inhibits the reaction [linalool results in increased expression of SLC27A4 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of SLC27A4 protein]
linalool results in increased expression of SLC27A4 mRNA; linalool results in increased expression of SLC27A4 protein
PPARA protein promotes the reaction [linalool results in increased expression of SLC27A4 protein]		 CTD PMID:24752549 NCBI chr 3:13,075,022...13,087,943
Ensembl chr 3:13,075,022...13,087,943 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 decreases expression EXP linalool results in decreased expression of SLC6A3 mRNA CTD PMID:20536181 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SNAI1 mRNA CTD PMID:38000518 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SOD1 mRNA CTD PMID:38000518 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO linalool inhibits the reaction [SOD2 protein binds to SIRT3 protein]; linalool results in decreased activity of and results in increased acetylation of SOD2 protein CTD PMID:28567457 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sox11 SRY-box transcription factor 11 increases expression EXP linalool results in increased expression of SOX11 mRNA CTD PMID:20536181 NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions EXP linalool inhibits the reaction [[Phosphates co-treated with Adenine] results in increased expression of SPP1 mRNA] CTD PMID:30466616 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Sqle squalene epoxidase increases expression ISO linalool results in increased expression of SQLE mRNA CTD PMID:24752549 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions
decreases expression		 ISO linalool inhibits the reaction [SREBF2 protein binds to HMGCR promoter]
linalool results in decreased expression of SREBF2 mRNA; linalool results in decreased expression of SREBF2 protein		 CTD PMID:21944868 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of TGFB1 mRNA CTD PMID:38000518 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Th tyrosine hydroxylase decreases expression EXP linalool results in decreased expression of TH mRNA CTD PMID:20536181 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP		 linalool inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; linalool inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; linalool inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]
linalool inhibits the reaction [Methamphetamine results in increased expression of TNF protein]		 CTD PMID:29276222 PMID:37729970 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 increases expression
increases response to substance		 ISO linalool results in increased expression of TP53 mRNA; linalool results in increased expression of TP53 protein
TP53 results in increased susceptibility to linalool		 CTD PMID:19922762 PMID:26703569 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO linalool results in increased activity of TRPA1 protein CTD PMID:27735854 NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta decreases expression EXP linalool results in decreased expression of TSHB mRNA CTD PMID:20536181 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
G Txn1 thioredoxin 1 increases expression ISO linalool results in increased expression of TXN mRNA CTD PMID:20491607 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions
increases expression		 ISO PPARA protein promotes the reaction [linalool results in increased expression of UCP2 protein]
PPARA gene mutant form inhibits the reaction [linalool results in increased expression of UCP2 mRNA]; PPARA gene mutant form inhibits the reaction [linalool results in increased expression of UCP2 protein]
linalool results in increased expression of UCP2 mRNA; linalool results in increased expression of UCP2 protein		 CTD PMID:24752549 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of linalool CTD PMID:7574722 NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589 		JBrowse link
G Ugt2b34l1 UDP glucuronosyltransferase 2 family, polypeptide B34 like 1 multiple interactions ISO linalool inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA] CTD PMID:31393563 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO linalool inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] CTD PMID:29276222 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vof16 ischemia related factor vof-16 increases expression EXP linalool results in increased expression of VOF16 mRNA CTD PMID:20536181 NCBI chr 8:41,953,062...41,955,169 JBrowse link
G Wnt1 Wnt family member 1 increases expression ISO linalool results in increased expression of WNT1 mRNA CTD PMID:19922762 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
G Wsb1 WD repeat and SOCS box-containing 1 increases expression ISO linalool results in increased expression of WSB1 mRNA CTD PMID:19922762 NCBI chr10:64,202,761...64,219,039
Ensembl chr10:64,202,763...64,219,019 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB1 mRNA CTD PMID:38000518 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB2 mRNA CTD PMID:38000518 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
(R)-linalyl acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACACA mRNA CTD PMID:38000518 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acacb acetyl-CoA carboxylase beta multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ACACB mRNA CTD PMID:38000518 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655 		JBrowse link
G Acly ATP citrate lyase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACLY mRNA CTD PMID:38000518 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACTA2 mRNA CTD PMID:38000518 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AHR mRNA CTD PMID:38000518 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AKT1 mRNA CTD PMID:38000518 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ar androgen receptor multiple interactions ISO linalyl acetate inhibits the reaction [Testosterone results in increased activity of AR protein] CTD PMID:31393563 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Cat catalase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of CAT mRNA CTD PMID:38000518 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA CTD PMID:38000518 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of COL1A1 mRNA CTD PMID:38000518 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT1A mRNA CTD PMID:38000518 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT2 mRNA CTD PMID:38000518 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095 		JBrowse link
G Ctsd cathepsin D increases expression
multiple interactions		 ISO linalyl acetate results in increased expression of CTSD mRNA
Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of CTSD mRNA]		 CTD PMID:31393563 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CYP1A1 mRNA CTD PMID:38000518 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 multiple interactions ISO linalyl acetate inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA] CTD PMID:31393563 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of DGAT1 mRNA CTD PMID:38000518 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Esr1 estrogen receptor 1 increases activity
multiple interactions		 ISO linalyl acetate results in increased activity of ESR1 protein
NCOA2 protein promotes the reaction [linalyl acetate results in increased activity of ESR1 protein]		 CTD PMID:31393563 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FASN mRNA CTD PMID:38000518 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FOXO1 mRNA CTD PMID:38000518 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GPX1 mRNA CTD PMID:38000518 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 increases expression
multiple interactions		 ISO linalyl acetate results in increased expression of GREB1 mRNA
Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of GREB1 mRNA]		 CTD PMID:31393563 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GSR mRNA CTD PMID:38000518 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] CTD PMID:29276222 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Mlycd malonyl-CoA decarboxylase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of MLYCD mRNA CTD PMID:38000518 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO NCOA2 protein promotes the reaction [linalyl acetate results in increased activity of ESR1 protein] CTD PMID:31393563 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFE2L2 mRNA CTD PMID:38000518 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFKB1 mRNA CTD PMID:38000518 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Pgr progesterone receptor increases expression
multiple interactions		 ISO linalyl acetate results in increased expression of PGR mRNA
Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of PGR mRNA]		 CTD PMID:31393563 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PPARA mRNA CTD PMID:38000518 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PTGS1 mRNA CTD PMID:38000518 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of and affects the localization of RELA protein modified form] CTD PMID:29276222 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO linalyl acetate inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788 		JBrowse link
G Sele selectin E multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELE mRNA] CTD PMID:29276222 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Selp selectin P multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELP mRNA] CTD PMID:29276222 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SNAI1 mRNA CTD PMID:38000518 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SOD1 mRNA CTD PMID:38000518 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of TGFB1 mRNA CTD PMID:38000518 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of and affects the localization of RELA protein modified form]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELP mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] CTD PMID:29276222 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Ugt2b34l1 UDP glucuronosyltransferase 2 family, polypeptide B34 like 1 multiple interactions ISO linalyl acetate inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA] CTD PMID:31393563 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] CTD PMID:29276222 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB1 mRNA CTD PMID:38000518 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB2 mRNA CTD PMID:38000518 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
linalyl acetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACACA mRNA CTD PMID:38000518 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acacb acetyl-CoA carboxylase beta multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ACACB mRNA CTD PMID:38000518 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655 		JBrowse link
G Acly ATP citrate lyase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACLY mRNA CTD PMID:38000518 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACTA2 mRNA CTD PMID:38000518 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AHR mRNA CTD PMID:38000518 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of AKT1 mRNA CTD PMID:38000518 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ar androgen receptor multiple interactions ISO linalyl acetate inhibits the reaction [Testosterone results in increased activity of AR protein] CTD PMID:31393563 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Cat catalase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of CAT mRNA CTD PMID:38000518 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA CTD PMID:38000518 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of COL1A1 mRNA CTD PMID:38000518 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT1A mRNA CTD PMID:38000518 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CPT2 mRNA CTD PMID:38000518 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095 		JBrowse link
G Ctsd cathepsin D increases expression
multiple interactions		 ISO linalyl acetate results in increased expression of CTSD mRNA
Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of CTSD mRNA]		 CTD PMID:31393563 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CYP1A1 mRNA CTD PMID:38000518 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 multiple interactions ISO linalyl acetate inhibits the reaction [Testosterone results in increased expression of CYP4F8 mRNA] CTD PMID:31393563 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of DGAT1 mRNA CTD PMID:38000518 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity		 ISO NCOA2 protein promotes the reaction [linalyl acetate results in increased activity of ESR1 protein] CTD PMID:31393563 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FASN mRNA CTD PMID:38000518 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of FOXO1 mRNA CTD PMID:38000518 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GPX1 mRNA CTD PMID:38000518 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
increases expression		 ISO Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of GREB1 mRNA] CTD PMID:31393563 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of GSR mRNA CTD PMID:38000518 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] CTD PMID:29276222 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Mlycd malonyl-CoA decarboxylase multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of MLYCD mRNA CTD PMID:38000518 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO NCOA2 protein promotes the reaction [linalyl acetate results in increased activity of ESR1 protein] CTD PMID:31393563 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFE2L2 mRNA CTD PMID:38000518 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of NFKB1 mRNA CTD PMID:38000518 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Pgr progesterone receptor multiple interactions
increases expression		 ISO Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of PGR mRNA] CTD PMID:31393563 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PPARA mRNA CTD PMID:38000518 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of PTGS1 mRNA CTD PMID:38000518 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of and affects the localization of RELA protein modified form] CTD PMID:29276222 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Sec14l2 SEC14-like lipid binding 2 multiple interactions ISO linalyl acetate inhibits the reaction [Testosterone results in increased expression of SEC14L2 mRNA] CTD PMID:31393563 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788 		JBrowse link
G Sele selectin E multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELE mRNA] CTD PMID:29276222 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Selp selectin P multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELP mRNA] CTD PMID:29276222 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SNAI1 mRNA CTD PMID:38000518 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of SOD1 mRNA CTD PMID:38000518 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of TGFB1 mRNA CTD PMID:38000518 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of and affects the localization of RELA protein modified form]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of SELP mRNA]; linalyl acetate inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] CTD PMID:29276222 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Ugt2b34l1 UDP glucuronosyltransferase 2 family, polypeptide B34 like 1 multiple interactions ISO linalyl acetate inhibits the reaction [Testosterone results in increased expression of UGT2B28 mRNA] CTD PMID:31393563 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO linalyl acetate inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] CTD PMID:29276222 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB1 mRNA CTD PMID:38000518 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 multiple interactions ISO [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of ZEB2 mRNA CTD PMID:38000518 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        antimicrobial agent 18240
          linalool 149
            (R)-linalool 0
            (S)-linalool 0
            3,7-dimethylocta-1,6-dien-3-yl acetate + 42
            linalool hydroperoxide + 0
            linaloyl diphosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    main group molecular entity 19811
                      s-block molecular entity 19647
                        hydrogen molecular entity 19628
                          hydrides 19139
                            organic hydride 18687
                              organic fundamental parent 18687
                                hydrocarbon 18438
                                  terpene 14063
                                    monoterpene 3831
                                      monoterpenoid 2042
                                        linalool 149
                                          (R)-linalool 0
                                          (S)-linalool 0
                                          3,7-dimethylocta-1,6-dien-3-yl acetate + 42
                                          linalool hydroperoxide + 0
                                          linaloyl diphosphate 0
paths to the root