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ONTOLOGY REPORT - ANNOTATIONS


Term:biochanin A
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Accession:CHEBI:17574 term browser browse the term
Definition:A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone which is substituted by an additional hydroxy group at position 5 and a methoxy group at position 4'. A phytoestrogen, it has putative benefits in dietary cancer prophylaxis.
Synonyms:exact_synonym: 5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one
 related_synonym: 4'-methylgenistein;   5,7-dihydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one;   5,7-dihydroxy-3-p-methoxyphenyl-4H-chromen-4-one;   5,7-dihydroxy-4'-methoxyisoflavone;   Formula=C16H12O5;   InChI=1S/C16H12O5/c1-20-11-4-2-9(3-5-11)12-8-21-14-7-10(17)6-13(18)15(14)16(12)19/h2-8,17-18H,1H3;   InChIKey=WUADCCWRTIWANL-UHFFFAOYSA-N;   SMILES=COc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O;   olmelin;   pratensol
 alt_id: CHEBI:13903;   CHEBI:22876;   CHEBI:3105
 xref: Beilstein:278107;   CAS:491-80-5;   HMDB:HMDB0002338;   KEGG:C00814;   KNApSAcK:C00002510;   LIPID_MAPS_instance:LMPK12050229
 xref_mesh: MESH:C004541
 xref: MetaCyc:BIOCHANIN-A;   PDBeChem:QSO;   PMID:11348577;   PMID:11931850;   PMID:15277096;   PMID:18060767;   PMID:20590565;   PMID:23406166;   PMID:23649249;   PMID:23948065;   PMID:24129051;   PMID:24201306;   PMID:28166217;   PMID:8947298;   Reaxys:278107;   Wikipedia:Biochanin_A
 cyclic_relationship: is_conjugate_acid_of CHEBI:58194


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biochanin A term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 JBrowse link 16 14,361,453 14,474,878 RGD:6480464
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 JBrowse link 19 43,782,308 43,838,332 RGD:6480464
G Agrn agrin JBrowse link 4 156,165,290 156,197,533 RGD:6480464
G Ahr aryl-hydrocarbon receptor JBrowse link 12 35,497,979 35,534,989 RGD:6480464
G Aldh7a1 aldehyde dehydrogenase family 7, member A1 JBrowse link 18 56,524,722 56,572,991 RGD:6480464
G Arid5b AT rich interactive domain 5B (MRF1-like) JBrowse link 10 68,092,523 68,279,355 RGD:6480464
G Babam2 BRISC and BRCA1 A complex member 2 JBrowse link 5 31,697,978 32,084,950 RGD:6480464
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:6480464
G Bcl2l1 BCL2-like 1 JBrowse link 2 152,758,732 152,833,803 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Cdh2 cadherin 2 JBrowse link 18 16,588,877 16,809,246 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) JBrowse link 17 29,090,979 29,100,722 RGD:6480464
G Ckb creatine kinase, brain JBrowse link 12 111,669,355 111,672,338 RGD:6480464
G Cxcl15 chemokine (C-X-C motif) ligand 15 JBrowse link 5 90,794,534 90,803,067 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 9 54,165,937 54,268,164 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 9 57,687,928 57,703,824 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 9 57,676,937 57,683,655 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 17 79,706,940 79,715,061 RGD:6480464
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 10 127,048,246 127,054,884 RGD:6480464
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 JBrowse link 19 39,061,006 39,093,948 RGD:6480464
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 JBrowse link 19 39,113,898 39,186,756 RGD:6480464
G Dera deoxyribose-phosphate aldolase (putative) JBrowse link 6 137,754,577 137,837,872 RGD:6480464
G Eif5 eukaryotic translation initiation factor 5 JBrowse link 12 111,538,101 111,546,753 RGD:6480464
G Enpp5 ectonucleotide pyrophosphatase/phosphodiesterase 5 JBrowse link 17 44,078,802 44,086,567 RGD:6480464
G Eps15 epidermal growth factor receptor pathway substrate 15 JBrowse link 4 109,280,175 109,387,817 RGD:6480464
G Esr1 estrogen receptor 1 (alpha) JBrowse link 10 4,611,989 5,005,633 RGD:6480464
G Esr2 estrogen receptor 2 (beta) JBrowse link 12 76,120,419 76,177,259 RGD:6480464
G Esrra estrogen related receptor, alpha JBrowse link 19 6,910,977 6,922,048 RGD:6480464
G Esrrb estrogen related receptor, beta JBrowse link 12 86,361,117 86,521,628 RGD:6480464
G Esrrg estrogen-related receptor gamma JBrowse link 1 187,608,510 188,214,885 RGD:6480464
G Fbl fibrillarin JBrowse link 7 28,168,893 28,179,269 RGD:6480464
G Folr1 folate receptor 1 (adult) JBrowse link 7 101,858,331 101,870,788 RGD:6480464
G Gm2a GM2 ganglioside activator protein JBrowse link 11 55,097,985 55,113,029 RGD:6480464
G Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 JBrowse link 3 108,107,275 108,146,152 RGD:6480464
G Gpx1 glutathione peroxidase 1 JBrowse link 9 108,339,080 108,340,342 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 9 21,015,940 21,028,814 RGD:6480464
G Il17a interleukin 17A JBrowse link 1 20,730,905 20,734,496 RGD:6480464
G Il4 interleukin 4 JBrowse link 11 53,612,460 53,618,665 RGD:6480464
G Lck lymphocyte protein tyrosine kinase JBrowse link 4 129,548,344 129,573,641 RGD:6480464
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 JBrowse link 18 67,932,274 68,260,550 RGD:6480464
G Lxn latexin JBrowse link 3 67,457,999 67,463,907 RGD:6480464
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) JBrowse link 14 54,431,598 54,442,456 RGD:6480464
G Mmp2 matrix metallopeptidase 2 JBrowse link 8 92,827,290 92,853,421 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 2 164,940,326 164,955,850 RGD:6480464
G Mt2 metallothionein 2 JBrowse link 8 94,172,618 94,173,567 RGD:6480464
G Ncoa1 nuclear receptor coactivator 1 JBrowse link 12 4,247,362 4,477,206 RGD:6480464
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 JBrowse link 6 24,518,662 24,527,690 RGD:6480464
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha JBrowse link 12 55,489,409 55,492,647 RGD:6480464
G Nono non-POU-domain-containing, octamer binding protein JBrowse link X 101,429,560 101,448,593 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 10 89,454,234 89,533,645 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase family, member 1 JBrowse link 1 180,568,891 180,600,999 RGD:6480464
G Pfdn5 prefoldin 5 JBrowse link 15 102,326,116 102,331,490 RGD:6480464
G Pgr progesterone receptor JBrowse link 9 8,898,900 8,968,611 RGD:6480464
G Plaur plasminogen activator, urokinase receptor JBrowse link 7 24,460,937 24,475,970 RGD:6480464
G Pnrc1 proline-rich nuclear receptor coactivator 1 JBrowse link 4 33,245,423 33,248,787 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:6480464
G Rabl6 RAB, member RAS oncogene family-like 6 JBrowse link 2 25,583,017 25,608,481 RGD:6480464
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) JBrowse link 19 5,637,442 5,648,134 RGD:6480464
G Rif1 replication timing regulatory factor 1 JBrowse link 2 52,072,815 52,126,769 RGD:6480464
G Rorc RAR-related orphan receptor gamma JBrowse link 3 94,372,794 94,398,276 RGD:6480464
G Rpusd3 RNA pseudouridylate synthase domain containing 3 JBrowse link 6 113,415,319 113,419,348 RGD:6480464
G Sh3gl1 SH3-domain GRB2-like 1 JBrowse link 17 56,016,750 56,036,659 RGD:6480464
G Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 JBrowse link 3 104,638,664 104,658,462 RGD:6480464
G Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 JBrowse link 10 91,116,574 91,124,046 RGD:6480464
G Srsf1 serine and arginine-rich splicing factor 1 JBrowse link 11 88,046,499 88,053,757 RGD:6480464
G Sult1a1 sulfotransferase family 1A, phenol-preferring, member 1 JBrowse link 7 126,672,865 126,690,443 RGD:6480464
G Sult1e1 sulfotransferase family 1E, member 1 JBrowse link 5 87,575,968 87,591,611 RGD:6480464
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 JBrowse link 7 13,796,246 13,837,410 RGD:6480464
G Susd6 sushi domain containing 6 JBrowse link 12 80,790,532 80,880,833 RGD:6480464
G Syk spleen tyrosine kinase JBrowse link 13 52,582,610 52,648,792 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:6480464
G Tnfrsf21 tumor necrosis factor receptor superfamily, member 21 JBrowse link 17 43,016,555 43,089,188 RGD:6480464
G Tubb5 tubulin, beta 5 class I JBrowse link 17 35,833,920 35,838,301 RGD:6480464
G Tyr tyrosinase JBrowse link 7 87,424,771 87,493,512 RGD:6480464
G Ube2d2a ubiquitin-conjugating enzyme E2D 2A JBrowse link 18 35,771,559 35,807,172 RGD:6480464
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 JBrowse link 1 88,211,959 88,220,002 RGD:6480464
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 JBrowse link 1 88,055,411 88,220,002 RGD:6480464
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 JBrowse link 1 88,070,779 88,220,002 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 3 116,110,020 116,129,688 RGD:6480464
G Wdr74 WD repeat domain 74 JBrowse link 19 8,735,795 8,740,624 RGD:6480464
G Wwc2 WW, C2 and coiled-coil domain containing 2 JBrowse link 8 47,826,082 47,990,544 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21260
    role 21244
      application 20679
        pharmaceutical 20060
          drug 20060
            antineoplastic agent 17325
              biochanin A 81
                2,3-dihydrobiochanin A 0
                biochanin A 7-O-(6-O-malonyl-beta-D-glucoside) 0
                biochanin A 7-O-beta-D-glucoside 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 21260
    subatomic particle 21256
      composite particle 21256
        hadron 21256
          baryon 21256
            nucleon 21256
              atomic nucleus 21256
                atom 21256
                  main group element atom 21122
                    p-block element atom 21122
                      carbon group element atom 20893
                        carbon atom 20784
                          organic molecular entity 20784
                            organic group 19177
                              organic divalent group 19167
                                organodiyl group 19167
                                  carbonyl group 19137
                                    carbonyl compound 19137
                                      ketone 16273
                                        cyclic ketone 13592
                                          isoflavones 2632
                                            methoxyisoflavone 235
                                              4'-methoxyisoflavones 129
                                                biochanin A 81
                                                  2,3-dihydrobiochanin A 0
                                                  biochanin A 7-O-(6-O-malonyl-beta-D-glucoside) 0
                                                  biochanin A 7-O-beta-D-glucoside 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.