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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cytidine
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Accession:CHEBI:17562 term browser browse the term
Definition:A pyrimidine nucleoside in which cytosine is attached to ribofuranose via a beta-N(1)-glycosidic bond.
Synonyms:related_synonym: 1-beta-D-Ribofuranosylcytosine;   1beta-D-ribofuranosylcytosine;   4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE;   4-amino-1-beta-D-ribofuranosylpyrimidin-2(1H)-one;   4-amino-1beta-D-ribofuranosyl-2(1H)-pyrimidinone;   Cyd;   Cytidin;   Cytosine riboside;   Formula=C9H13N3O5;   InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7-,8-/m1/s1;   InChIKey=UHDGCWIWMRVCDJ-XVFCMESISA-N;   SMILES=Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1;   Zytidin;   cytosine-1beta-D-Ribofuranoside
 alt_id: CHEBI:14063;   CHEBI:23515;   CHEBI:4053;   CHEBI:41649;   CHEBI:41686;   CHEBI:41704
 xref: Beilstein:89173;   CAS:65-46-3;   DrugBank:DB02097;   Gmelin:84763;   HMDB:HMDB0000089;   KEGG:C00475;   KEGG:D07769
 xref_mesh: MESH:D003562
 xref: MetaCyc:CYTIDINE;   PDBeChem:CTN;   PMID:12591866;   PMID:15621516;   PMID:19194376;   Reaxys:89173;   Wikipedia:Cytidine


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cytidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor increases activity EXP Cytidine results in increased activity of ADORA1 protein CTD PMID:18313046 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Adora2a adenosine A2a receptor increases activity EXP Cytidine results in increased activity of ADORA2A protein CTD PMID:18313046 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO [Chlorine binds to Cytidine] which results in decreased expression of CCL5 mRNA CTD PMID:31066272 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Gypa glycophorin A multiple interactions ISO Cytidine inhibits the reaction [teriflunomide results in increased expression of GYPA protein] CTD PMID:12181422 NCBI chr19:27,450,311...27,465,940 JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions
ISO IDH2 protein mutant form results in increased abundance of Cytidine
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Cytidine]
CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Chlorine binds to Cytidine] which results in increased expression of IL1B mRNA; [Chlorine binds to Cytidine] which results in increased expression of IL1B protein CTD PMID:31066272 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Slc28a1 solute carrier family 28 member 1 multiple interactions
increases transport
ISO Cytidine inhibits the reaction [SLC28A1 protein results in increased uptake of Uridine]
SLC28A1 protein results in increased transport of Cytidine
CTD PMID:9124315 PMID:10772724 NCBI chr 1:135,079,375...135,122,791
Ensembl chr 1:135,081,385...135,122,464
JBrowse link
G Slc29a1 solute carrier family 29 member 1 multiple interactions ISO
EXP
Cytidine inhibits the reaction [SLC29A1 protein results in increased uptake of Uridine] CTD PMID:9353301 PMID:11085929 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203
JBrowse link
G Slc29a2 solute carrier family 29 member 2 multiple interactions ISO Cytidine inhibits the reaction [SLC29A2 protein results in increased uptake of Uridine] CTD PMID:11085929 NCBI chr 1:202,327,641...202,335,185
Ensembl chr 1:202,327,354...202,335,171
JBrowse link
G Upp1 uridine phosphorylase 1 increases metabolic processing ISO UPP1 protein results in increased metabolism of Cytidine CTD PMID:15772079 NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        biochemical role 19389
          metabolite 19364
            eukaryotic metabolite 19052
              fungal metabolite 17444
                Saccharomyces cerevisiae metabolite 16509
                  cytidine 10
                    cytidine residue 0
                    ddhC 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            heteroorganic entity 19294
                              organochalcogen compound 19064
                                organooxygen compound 19014
                                  carbohydrates and carbohydrate derivatives 12341
                                    carbohydrate 12341
                                      carbohydrate derivative 11947
                                        glycosyl compound 10977
                                          N-glycosyl compound 5514
                                            nucleoside 5375
                                              ribonucleoside 674
                                                pyrimidine ribonucleosides 148
                                                  cytidines 67
                                                    cytidine 10
                                                      cytidine residue 0
                                                      ddhC 0
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