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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:alginic acid
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Accession:CHEBI:17548 term browser browse the term
Definition:A linear copolymer macromolecule composed of homopolymeric blocks of 1->4-linked beta-D-mannuronic acid and alpha-L-guluronic acid residues, covalently linked together in different sequences or blocks.
Synonyms:related_synonym: (Alginate)n+1;   (alginate)n;   Alginate;   Formula=(C12H16O13)n;   Formula=(C6H8O6)n.H2O;   Norgine
 alt_id: CHEBI:11097;   CHEBI:18823;   CHEBI:22308;   CHEBI:271
 xref: Beilstein:8192143;   CAS:9005-32-7;   KEGG:C01768;   KEGG:D02324;   KEGG:G10593
 xref_mesh: MESH:C008970
 xref: PMID:25449544;   Wikipedia:Alginic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:58187



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alginic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan increases expression ISO alginic acid results in increased expression of ACAN mRNA CTD PMID:16371897 NCBI chr 1:132,981,034...133,044,416
Ensembl chr 1:132,981,582...133,043,627
JBrowse link
G Atg12 autophagy related 12 increases expression ISO Alginic Acid results in increased expression of ATG12 protein CTD PMID:35066102 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
JBrowse link
G Atg7 autophagy related 7 increases expression ISO Alginic Acid results in increased expression of ATG7 protein CTD PMID:35066102 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Alginic Acid results in decreased expression of BCL2 protein CTD PMID:35066102 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO Alginic Acid results in decreased expression of BCL2L1 protein CTD PMID:35066102 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Becn1 beclin 1 increases expression ISO Alginic Acid results in increased expression of BECN1 protein CTD PMID:35066102 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Casp3 caspase 3 increases expression
increases cleavage
ISO Alginic Acid results in increased expression of CASP3 protein
Alginic Acid results in increased cleavage of CASP3 protein
CTD PMID:35066102 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Alginic Acid results in increased expression of and results in increased cleavage of CASP8 protein CTD PMID:35066102 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases expression ISO Alginic Acid results in increased expression of CASP9 protein CTD PMID:35066102 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases expression ISO Alginic Acid results in decreased expression of CAT protein CTD PMID:35066102 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Col10a1 collagen type X alpha 1 chain increases expression ISO alginic acid results in increased expression of COL10A1 mRNA CTD PMID:16371897 NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression ISO Alginic Acid results in increased expression of CYP17A1 protein CTD PMID:35066102 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression ISO Alginic Acid results in decreased expression of CYP19A1 protein CTD PMID:35066102 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression ISO Alginic Acid results in decreased expression of FSHR protein CTD PMID:35066102 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
JBrowse link
G Gpx5 glutathione peroxidase 5 decreases expression ISO Alginic Acid results in decreased expression of GPX5 protein CTD PMID:35066102 NCBI chr17:43,436,126...43,443,074
Ensembl chr17:43,416,340...43,443,074
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO alginic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:12723939 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases lipidation ISO Alginic Acid results in increased lipidation of MAP1LC3B protein CTD PMID:35066102 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Alginic Acid results in increased expression of and results in increased cleavage of PARP1 protein CTD PMID:35066102 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Rab7a RAB7A, member RAS oncogene family increases expression ISO Alginic Acid results in increased expression of RAB7 protein CTD PMID:35066102 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression ISO Alginic Acid results in decreased expression of SOD1 protein CTD PMID:35066102 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO Alginic Acid results in decreased expression of SOD2 protein CTD PMID:35066102 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO Alginic Acid results in decreased expression of SQSTM1 protein CTD PMID:35066102 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO Alginic Acid results in decreased expression of STAR protein CTD PMID:35066102 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO alginic acid inhibits the reaction [TNF protein results in increased abundance of Hydrogen Peroxide]; alginic acid inhibits the reaction [TNF protein results in increased abundance of Nitric Oxide]; alginic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:12723939 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20057
    role 20023
      application 19770
        pharmaceutical 19645
          drug 19645
            hematologic agent 4564
              alginic acid 24
Path 2
Term Annotations click to browse term
  CHEBI ontology 20057
    subatomic particle 20056
      composite particle 20068
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19971
                    p-block element atom 19971
                      carbon group element atom 19889
                        carbon atom 19894
                          organic molecular entity 19882
                            heteroorganic entity 19593
                              organochalcogen compound 19369
                                organooxygen compound 19262
                                  carbohydrates and carbohydrate derivatives 13979
                                    carbohydrate 13997
                                      polysaccharide 3258
                                        heteroglycan 24
                                          alginic acid 24
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