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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:L-cystathionine
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Accession:CHEBI:17482 term browser browse the term
Definition:A modified amino acid generated by enzymic means from L-homocysteine and L-serine.
Synonyms:exact_synonym: (2S)-2-amino-4-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}butanoic acid
 related_synonym: (R)-S-(2-amino-2-carboxyethyl)-L-Homocysteine;   Formula=C7H14N2O4S;   InChI=1S/C7H14N2O4S/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)/t4-,5-/m0/s1;   InChIKey=ILRYLPWNYFXEMH-WHFBIAKZSA-N;   S-(beta-amino-beta-carboxyethyl)homocysteine;   SMILES=N[C@@H](CCSC[C@H](N)C(O)=O)C(O)=O
 alt_id: CHEBI:13093;   CHEBI:21259;   CHEBI:6205
 xref: CAS:56-88-2;   HMDB:HMDB0000099;   KEGG:C02291;   KNApSAcK:C00007498
 xref_mesh: MESH:D003540
 xref: MetaCyc:CYSTATHIONINE;   PMID:1025897;   Reaxys:2331423;   Wikipedia:Cystathionine
 cyclic_relationship: is_tautomer_of CHEBI:58161



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L-cystathionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin 2 multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Cystathionine analog CTD PMID:26820058 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Kyat1 kynurenine aminotransferase 1 increases amination ISO KYAT1 protein results in increased amination of Cystathionine CTD PMID:22093698 NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO Cystathionine inhibits the reaction [Formaldehyde results in increased expression of MMP1 protein] CTD PMID:27664576 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    role 20008
      biological role 20007
        biochemical role 19640
          metabolite 19623
            cystathionine 3
              L-cystathionine 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19875
                          organic molecular entity 19875
                            organic group 18961
                              organic divalent group 18947
                                organodiyl group 18947
                                  carbonyl group 18900
                                    carbonyl compound 18900
                                      carboxylic acid 18594
                                        amino acid 14919
                                          alpha-amino acid 12937
                                            non-proteinogenic alpha-amino acid 1775
                                              homocysteines 410
                                                cystathionines 3
                                                  cystathionine 3
                                                    L-cystathionine 3
paths to the root