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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:L-cystathionine
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Accession:CHEBI:17482 term browser browse the term
Definition:A modified amino acid generated by enzymic means from L-homocysteine and L-serine.
Synonyms:exact_synonym: (2S)-2-amino-4-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}butanoic acid
 related_synonym: (R)-S-(2-amino-2-carboxyethyl)-L-Homocysteine;   Formula=C7H14N2O4S;   InChI=1S/C7H14N2O4S/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)/t4-,5-/m0/s1;   InChIKey=ILRYLPWNYFXEMH-WHFBIAKZSA-N;   S-(beta-amino-beta-carboxyethyl)homocysteine;   SMILES=N[C@@H](CCSC[C@H](N)C(O)=O)C(O)=O
 alt_id: CHEBI:13093;   CHEBI:21259;   CHEBI:6205
 xref: CAS:56-88-2;   HMDB:HMDB0000099;   KEGG:C02291;   KNApSAcK:C00007498
 xref_mesh: MESH:D003540
 xref: MetaCyc:CYSTATHIONINE;   PMID:1025897;   Reaxys:2331423;   Wikipedia:Cystathionine
 cyclic_relationship: is_tautomer_of CHEBI:58161


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L-cystathionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin 2 multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Cystathionine analog CTD PMID:26820058 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Kyat1 kynurenine aminotransferase 1 increases amination ISO KYAT1 protein results in increased amination of Cystathionine CTD PMID:22093698 NCBI chr 3:8,752,289...8,785,617
Ensembl chr 3:8,752,625...8,766,433
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO Cystathionine inhibits the reaction [Formaldehyde results in increased expression of MMP1 protein] CTD PMID:27664576 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        biochemical role 19313
          metabolite 19294
            cystathionine 3
              L-cystathionine 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic group 18537
                              organic divalent group 18530
                                organodiyl group 18530
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18114
                                        amino acid 14085
                                          alpha-amino acid 11550
                                            non-proteinogenic alpha-amino acid 1545
                                              homocysteines 393
                                                cystathionines 3
                                                  cystathionine 3
                                                    L-cystathionine 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.