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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone
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Accession:CHEBI:174791 term browser browse the term
Synonyms:exact_synonym: 1-(4-tert-butyl-2,6-dimethyl-3,5-dinitrophenyl)ethanone
 related_synonym: Formula=C14H18N2O5;   InChI=1S/C14H18N2O5/c1-7-10(9(3)17)8(2)13(16(20)21)11(14(4,5)6)12(7)15(18)19/h1-6H3;   InChIKey=WXCMHFPAUCOJIG-UHFFFAOYSA-N;   SMILES=[O-][N+](=O)C1=C(C(C)(C)C)C([N+]([O-])=O)=C(C(=C1C)C(=O)C)C
 xref: CAS:81-14-1;   Chemspider:6417;   HMDB:HMDB0031865
 xref_mesh: MESH:C031448


show annotations for term's descendants           Sort by:
4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
increases activity		 EXP musk ketone results in increased expression of CYP1A1 protein
musk ketone results in increased activity of CYP1A1 protein		 CTD PMID:10630706 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
increases expression		 EXP
ISO		 musk ketone results in increased activity of CYP1A2 protein
musk ketone results in increased expression of CYP1A2 mRNA
musk ketone results in increased expression of CYP1A2 protein		 CTD PMID:9441723 PMID:10630706 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases activity
increases expression		 EXP musk ketone results in increased activity of CYP2B1 protein
musk ketone results in increased expression of CYP2B1 mRNA; musk ketone results in increased expression of CYP2B1 protein		 CTD PMID:10630706 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases activity
increases expression		 EXP musk ketone results in increased activity of CYP2B2 protein
musk ketone results in increased expression of CYP2B2 protein		 CTD PMID:10630706 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity EXP musk ketone results in decreased activity of CYP3A2 protein CTD PMID:10630706 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 decreases activity EXP musk ketone results in decreased activity of CYP3A23-3A1 protein CTD PMID:10630706 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression ISO musk ketone results in increased expression of CYP3A9 mRNA CTD PMID:9441723 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP musk ketone results in increased expression of GFAP mRNA CTD PMID:22954530 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19831
    chemical entity 19829
      group 19788
        inorganic group 19381
          oxo group 18874
            organic oxo compound 18874
              carbonyl compound 18874
                ketone 17181
                  aromatic ketone 12455
                    4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19831
    subatomic particle 19829
      composite particle 19829
        hadron 19829
          baryon 19829
            nucleon 19829
              atomic nucleus 19829
                atom 19829
                  main group element atom 19779
                    p-block element atom 19779
                      carbon group element atom 19728
                        carbon atom 19724
                          organic molecular entity 19724
                            heteroorganic entity 19477
                              organochalcogen compound 19240
                                organooxygen compound 19155
                                  carbonyl compound 18874
                                    ketone 17181
                                      aromatic ketone 12455
                                        4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone 8
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