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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hypoxanthine
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Accession:CHEBI:17368 term browser browse the term
Definition:A purine nucleobase that consists of purine bearing an oxo substituent at position 6.
Synonyms:related_synonym: 1,7-Dihydro-6H-purin-6-one;   6(1H)-purinone;   6-oxopurine;   9H-purin-6(1H)-one;   Formula=C5H4N4O;   Hyp;   InChI=1S/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10);   InChIKey=FDGQSTZJBFJUBT-UHFFFAOYSA-N;   Purine-6-ol;   SMILES=O=c1[nH]cnc2nc[nH]c12;   purin-6(1H)-one
 alt_id: CHEBI:14431;   CHEBI:24762;   CHEBI:43237;   CHEBI:5841
 xref: Beilstein:5811;   CAS:68-94-0;   DrugBank:DB04076;   ECMDB:ECMDB00157;   Gmelin:464558;   HMDB:HMDB0000157;   KEGG:C00262;   KNApSAcK:C00001502
 xref_mesh: MESH:D019271
 xref: MetaCyc:HYPOXANTHINE;   PDBeChem:HPA;   PMID:14253484;   PMID:1557408;   PMID:22735334;   PMID:23400363;   PMID:23670363;   PMID:8016081;   Reaxys:5811;   Wikipedia:Hypoxanthine;   YMDB:YMDB00555

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hypoxanthine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase multiple interactions EXP CAT protein inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide]; CAT protein results in decreased activity of [Hypoxanthine co-treated with XDH protein] CTD PMID:21984542 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452 		JBrowse link
G XDH xanthine dehydrogenase multiple interactions EXP [Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide; [Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Hydrogen Peroxide; [Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Superoxides; CAT protein inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide]; CAT protein results in decreased activity of [Hypoxanthine co-treated with XDH protein]; tempol inhibits the reaction [[Hypoxanthine co-treated with XDH protein] results in increased chemical synthesis of Carbon Monoxide]; tempol results in decreased activity of [Hypoxanthine co-treated with XDH protein] CTD PMID:21984542 NCBI chr 3:107,987,060...108,052,043
Ensembl chr 3:107,986,528...108,080,151 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 875
    role 855
      biological role 855
        biochemical role 726
          metabolite 714
            fundamental metabolite 92
              hypoxanthine 2
                9-riburonosylhypoxanthine 0
                inosine + 0
                methylhypoxanthine + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 875
    subatomic particle 860
      composite particle 860
        hadron 860
          baryon 860
            nucleon 860
              atomic nucleus 860
                atom 860
                  main group element atom 850
                    p-block element atom 847
                      carbon group element atom 823
                        carbon atom 822
                          organic molecular entity 822
                            organic molecule 735
                              organic cyclic compound 645
                                organic heterocyclic compound 361
                                  organic heteropolycyclic compound 252
                                    organic heterobicyclic compound 100
                                      imidazopyrimidine 23
                                        purines 23
                                          aminopurine 17
                                            6-aminopurines 13
                                              adenine 13
                                                hypoxanthine 2
                                                  9-riburonosylhypoxanthine 0
                                                  inosine + 0
                                                  methylhypoxanthine + 0
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