|
G |
Abca1 |
ATP binding cassette subfamily A member 1 |
multiple interactions decreases expression increases expression increases phosphorylation increases degradation |
ISO |
1-Butanol inhibits the reaction [Linoleic Acid inhibits the reaction [ABCA1 protein results in increased export of Cholesterol]]; Linoleic Acid inhibits the reaction [ABCA1 protein results in increased export of Cholesterol]; Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]]; PLD2 protein inhibits the reaction [Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased export of Cholesterol]]]; triacsin C inhibits the reaction [Linoleic Acid inhibits the reaction [ABCA1 protein results in increased transport of Cholesterol]]; triacsin C inhibits the reaction [Linoleic Acid inhibits the reaction [ABCA1 protein results in increased transport of Phospholipids]]; triacsin C inhibits the reaction [Linoleic Acid results in increased degradation of ABCA1 protein] Linoleic Acid analog results in decreased expression of ABCA1 mRNA Linoleic Acid results in increased expression of ABCA1 mRNA Linoleic Acid inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mRNA] Linoleic Acid results in increased phosphorylation of ABCA1 protein |
CTD |
PMID:16118212 PMID:18356535 PMID:27939595 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
decreases expression |
ISO |
Linoleic Acid results in decreased expression of ABCG1 mRNA; Linoleic Acid results in decreased expression of ABCG1 protein |
CTD |
PMID:16730733 |
|
NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Acaca |
acetyl-CoA carboxylase alpha |
decreases expression |
EXP |
Linoleic Acid results in decreased expression of ACACA mRNA |
CTD |
PMID:14563831 |
|
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acadm |
acyl-CoA dehydrogenase medium chain |
increases expression |
EXP |
Linoleic Acid results in increased expression of ACADM mRNA |
CTD |
PMID:23056435 |
|
NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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G |
Acly |
ATP citrate lyase |
decreases expression |
EXP |
Linoleic Acid results in decreased expression of ACLY mRNA |
CTD |
PMID:14563831 |
|
NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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G |
Acmsd |
aminocarboxymuconate semialdehyde decarboxylase |
decreases expression |
EXP |
Linoleic Acid results in decreased expression of ACMSD mRNA |
CTD |
PMID:18320257 |
|
NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209
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G |
Acox1 |
acyl-CoA oxidase 1 |
increases expression |
EXP |
Linoleic Acid results in increased expression of ACOX1 mRNA |
CTD |
PMID:18320257 |
|
NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
decreases expression |
ISO |
Linoleic Acid results in decreased expression of ADIPOQ mRNA |
CTD |
PMID:17374693 |
|
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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|
G |
Adipor1 |
adiponectin receptor 1 |
increases expression |
ISO |
Linoleic Acid analog results in increased expression of ADIPOR1 mRNA |
CTD |
PMID:27939595 |
|
NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241
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|
G |
Ager |
advanced glycosylation end product-specific receptor |
multiple interactions |
EXP |
AGER protein results in increased susceptibility to [Azoxymethane co-treated with Glucose co-treated with Linoleic Acid]; Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]; Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]; Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]; Losartan inhibits the reaction [Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Losartan inhibits the reaction [Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Metformin inhibits the reaction [Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Metformin inhibits the reaction [Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]] |
CTD |
PMID:22467055 |
|
NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 promoter]]; Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]] |
CTD |
PMID:18001219 |
|
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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|
G |
Alox15 |
arachidonate 15-lipoxygenase |
increases oxidation |
ISO |
ALOX15 protein results in increased oxidation of Linoleic Acid |
CTD |
PMID:25786526 |
|
NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
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G |
Apoa1 |
apolipoprotein A1 |
multiple interactions |
ISO |
Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]]; PLD2 protein inhibits the reaction [Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased export of Cholesterol]]] |
CTD |
PMID:16118212 |
|
NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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|
G |
Ascl2 |
achaete-scute family bHLH transcription factor 2 |
decreases expression |
ISO |
Linoleic Acid results in decreased expression of ASCL2 mRNA |
CTD |
PMID:15708366 |
|
NCBI chr 1:198,148,999...198,151,406
Ensembl chr 1:198,148,999...198,151,406
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G |
Bche |
butyrylcholinesterase |
increases expression |
ISO |
Linoleic Acid results in increased expression of BCHE mRNA |
CTD |
PMID:27106529 |
|
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
EXP |
[Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of BCL2 protein]; Linoleic Acid affects the reaction [Azoxymethane affects the expression of BCL2 protein] |
CTD |
PMID:22467055 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Cat |
catalase |
increases expression multiple interactions |
ISO EXP |
Linoleic Acid results in increased expression of CAT protein Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in decreased activity of CAT protein] |
CTD |
PMID:10946007 PMID:34111468 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression |
ISO |
Linoleic Acid results in increased expression of CCL2 protein |
CTD |
PMID:16305726 |
|
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Cd36 |
CD36 molecule |
multiple interactions |
EXP |
[Oleic Acid co-treated with Linoleic Acid] results in increased expression of CD36 mRNA |
CTD |
PMID:28552552 |
|
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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|
G |
Chrna7 |
cholinergic receptor nicotinic alpha 7 subunit |
multiple interactions |
EXP |
Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in decreased expression of CHRNA7 mRNA] |
CTD |
PMID:34111468 |
|
NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
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G |
Cnr1 |
cannabinoid receptor 1 |
multiple interactions affects response to substance |
ISO |
CNR1 protein affects the reaction [Linoleic Acid results in increased secretion of GCG protein] CNR1 protein affects the susceptibility to Linoleic Acid |
CTD |
PMID:30241419 |
|
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Col1a1 |
collagen type I alpha 1 chain |
increases expression |
ISO |
Linoleic Acid results in increased expression of COL1A1 mRNA |
CTD |
PMID:26240151 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col3a1 |
collagen type III alpha 1 chain |
decreases expression |
ISO |
Linoleic Acid results in decreased expression of COL3A1 mRNA |
CTD |
PMID:26240151 |
|
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression |
EXP |
Linoleic Acid results in increased expression of CPT1A mRNA |
CTD |
PMID:11171094 |
|
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Crebbp |
CREB binding protein |
multiple interactions |
ISO |
Linoleic Acid affects the reaction [PPARA protein binds to CREBBP protein] |
CTD |
PMID:19263263 |
|
NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
ISO |
[Oleic Acid co-treated with Linoleic Acid] results in increased expression of CYCS protein |
CTD |
PMID:27016407 |
|
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 promoter]] |
CTD |
PMID:18001219 |
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
decreases activity |
ISO |
Linoleic Acid results in decreased activity of CYP1A2 protein |
CTD |
PMID:16978661 |
|
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp2c6v1 |
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 |
multiple interactions decreases activity |
ISO |
CYP2C19 protein results in increased metabolism of [Linoleic Acid co-treated with NADP] Linoleic Acid results in decreased activity of CYP2C19 protein |
CTD |
PMID:16978661 |
|
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
decreases activity |
ISO |
Linoleic Acid results in decreased activity of CYP2E1 protein |
CTD |
PMID:16978661 |
|
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
decreases activity |
ISO |
Linoleic Acid results in decreased activity of CYP3A4 protein |
CTD |
PMID:16978661 |
|
NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression |
ISO |
Linoleic Acid analog results in increased expression of DDIT3 protein |
CTD |
PMID:27939595 |
|
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Dio1 |
iodothyronine deiodinase 1 |
decreases activity |
ISO |
Linoleic Acid results in decreased activity of DIO1 protein |
CTD |
PMID:30561685 |
|
NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
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G |
Dio2 |
iodothyronine deiodinase 2 |
decreases activity |
ISO |
Linoleic Acid results in decreased activity of DIO2 protein |
CTD |
PMID:30561685 |
|
NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
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G |
Dio3 |
iodothyronine deiodinase 3 |
decreases activity |
ISO |
Linoleic Acid results in decreased activity of DIO3 protein |
CTD |
PMID:30561685 |
|
NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
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G |
Edn1 |
endothelin 1 |
decreases expression |
ISO |
Linoleic Acid results in decreased expression of EDN1 mRNA; Linoleic Acid results in decreased expression of EDN1 protein |
CTD |
PMID:16895544 |
|
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Fabp1 |
fatty acid binding protein 1 |
decreases expression |
ISO |
Linoleic Acid results in decreased expression of FABP1 mRNA |
CTD |
PMID:15708366 |
|
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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G |
Fabp3 |
fatty acid binding protein 3 |
decreases expression |
ISO |
Linoleic Acid results in decreased expression of FABP3 mRNA |
CTD |
PMID:15708366 |
|
NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
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G |
Fabp4 |
fatty acid binding protein 4 |
affects localization |
ISO |
Linoleic Acid analog affects the localization of FABP4 protein |
CTD |
PMID:27939595 |
|
NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
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G |
Fads2 |
fatty acid desaturase 2 |
multiple interactions increases expression |
ISO |
[Linoleic Acid co-treated with Testosterone] results in increased expression of FADS2 mRNA FADS2 protein inhibits the reaction [Linoleic Acid results in increased activity of LOX protein] Linoleic Acid results in increased expression of FADS2 mRNA; Linoleic Acid results in increased expression of FADS2 protein |
CTD |
PMID:21457203 PMID:26240151 |
|
NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
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G |
Fasn |
fatty acid synthase |
decreases expression |
EXP |
Linoleic Acid results in decreased expression of FASN mRNA |
CTD |
PMID:14563831 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Ffar3 |
free fatty acid receptor 3 |
increases expression |
ISO |
Linoleic Acid analog results in increased expression of FFAR3 mRNA |
CTD |
PMID:27939595 |
|
NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849
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G |
Foxo1 |
forkhead box O1 |
decreases expression |
ISO |
Linoleic Acid results in decreased expression of FOXO1 protein |
CTD |
PMID:17374693 |
|
NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G |
Gcg |
glucagon |
multiple interactions |
ISO |
CNR1 protein affects the reaction [Linoleic Acid results in increased secretion of GCG protein] |
CTD |
PMID:30241419 |
|
NCBI chr 3:47,113,914...47,122,929
Ensembl chr 3:47,113,914...47,122,929
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
increases expression |
ISO |
Linoleic Acid metabolite results in increased expression of GCLM mRNA |
CTD |
PMID:26879219 |
|
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Gjb1 |
gap junction protein, beta 1 |
increases abundance |
ISO |
GJB1 protein results in increased abundance of Linoleic Acid |
CTD |
PMID:27859493 |
|
NCBI chr X:66,501,848...66,509,783
Ensembl chr X:66,501,820...66,509,925
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G |
Grin2a |
glutamate ionotropic receptor NMDA type subunit 2A |
multiple interactions |
EXP |
Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of GRIN2A mRNA] |
CTD |
PMID:34111468 |
|
NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637
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G |
Grin2b |
glutamate ionotropic receptor NMDA type subunit 2B |
multiple interactions |
EXP |
Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of GRIN2B mRNA] |
CTD |
PMID:34111468 |
|
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
increases expression multiple interactions |
ISO |
Linoleic Acid results in increased expression of GSTA1 mRNA NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of GSTA1 mRNA] |
CTD |
PMID:28555106 |
|
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
increases secretion |
ISO |
Linoleic Acid results in increased secretion of HAVCR1 protein |
CTD |
PMID:31686351 |
|
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO |
NFE2L2 mRNA promotes the reaction [Linoleic Acid metabolite results in increased expression of HMOX1 mRNA] Linoleic Acid metabolite results in increased expression of HMOX1 mRNA; Linoleic Acid metabolite results in increased expression of HMOX1 protein |
CTD |
PMID:26879219 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
ISO |
Linoleic Acid analog results in increased expression of HSPA5 protein |
CTD |
PMID:27939595 |
|
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Ifng |
interferon gamma |
increases expression |
ISO |
Linoleic Acid results in increased expression of IFNG protein |
CTD |
PMID:16305726 |
|
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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|
G |
Il10 |
interleukin 10 |
increases expression |
ISO |
Linoleic Acid results in increased expression of IL10 protein |
CTD |
PMID:16305726 |
|
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il1b |
interleukin 1 beta |
increases expression multiple interactions |
ISO EXP |
Linoleic Acid results in increased expression of IL1B protein Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of IL1B mRNA] |
CTD |
PMID:16305726 PMID:34111468 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il2 |
interleukin 2 |
decreases expression |
ISO |
Linoleic Acid results in decreased expression of IL2 protein |
CTD |
PMID:16305726 |
|
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il4 |
interleukin 4 |
decreases expression |
ISO |
Linoleic Acid results in decreased expression of IL4 protein |
CTD |
PMID:16305726 |
|
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il5 |
interleukin 5 |
decreases expression |
ISO |
Linoleic Acid results in decreased expression of IL5 protein |
CTD |
PMID:16305726 |
|
NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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G |
Il6 |
interleukin 6 |
affects expression multiple interactions increases expression increases secretion |
ISO EXP |
Linoleic Acid affects the expression of IL6 protein Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of IL6 mRNA] Linoleic Acid results in increased expression of IL6 mRNA Linoleic Acid results in increased secretion of IL6 protein |
CTD |
PMID:16305726 PMID:17374693 PMID:21457203 PMID:34111468 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Insr |
insulin receptor |
increases expression |
ISO |
Linoleic Acid analog results in increased expression of INSR mRNA |
CTD |
PMID:27939595 |
|
NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
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G |
Iyd |
iodotyrosine deiodinase |
multiple interactions |
ISO |
Linoleic Acid inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] |
CTD |
PMID:33352258 |
|
NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
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|
G |
Lcat |
lecithin cholesterol acyltransferase |
increases expression |
ISO |
Linoleic Acid analog results in increased expression of LCAT mRNA |
CTD |
PMID:27939595 |
|
NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
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|
G |
Lipc |
lipase C, hepatic type |
multiple interactions |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Linoleic Acid |
CTD |
PMID:24777581 |
|
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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|
G |
Lipg |
lipase G, endothelial type |
multiple interactions |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Linoleic Acid |
CTD |
PMID:24777581 |
|
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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|
G |
Lox |
lysyl oxidase |
multiple interactions increases activity |
ISO |
FADS2 protein inhibits the reaction [Linoleic Acid results in increased activity of LOX protein]; TGFB1 protein promotes the reaction [Linoleic Acid results in increased activity of LOX protein] |
CTD |
PMID:26240151 |
|
NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
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G |
Lpin1 |
lipin 1 |
decreases expression |
ISO |
Linoleic Acid analog results in decreased expression of LPIN1 mRNA |
CTD |
PMID:27939595 |
|
NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
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G |
Lrat |
lecithin retinol acyltransferase |
increases expression |
EXP |
Linoleic Acid results in increased expression of LRAT mRNA |
CTD |
PMID:12576510 |
|
NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
Linoleic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:23288142 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions decreases expression |
ISO EXP |
Linoleic Acid results in decreased expression of and results in decreased activity of MMP9 protein [Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of MMP9 protein]; Linoleic Acid affects the reaction [Azoxymethane affects the expression of MMP9 protein] Linoleic Acid results in decreased expression of MMP9 mRNA |
CTD |
PMID:22467055 PMID:23288142 |
|
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Ncf1 |
neutrophil cytosolic factor 1 |
multiple interactions |
ISO |
Linoleic Acid affects the reaction [Zymosan analog affects the localization of NCF1 protein] |
CTD |
PMID:12101222 |
|
NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
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G |
Ncf2 |
neutrophil cytosolic factor 2 |
multiple interactions |
ISO |
Linoleic Acid affects the reaction [Zymosan analog affects the localization of NCF2 protein] |
CTD |
PMID:12101222 |
|
NCBI chr13:64,955,502...64,986,289
Ensembl chr13:64,955,503...64,986,277
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G |
Ncoa1 |
nuclear receptor coactivator 1 |
multiple interactions |
ISO |
Linoleic Acid promotes the reaction [PPARA protein binds to NCOA1 protein] |
CTD |
PMID:19263263 |
|
NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
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G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions |
ISO |
Linoleic Acid promotes the reaction [PPARA protein binds to NCOA2 protein] |
CTD |
PMID:19263263 |
|
NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
increases expression multiple interactions |
ISO |
Linoleic Acid metabolite results in increased expression of NFE2L2 protein; Linoleic Acid results in increased expression of NFE2L2 mRNA; Linoleic Acid results in increased expression of NFE2L2 protein NFE2L2 mRNA promotes the reaction [Linoleic Acid metabolite results in increased expression of HMOX1 mRNA]; NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of CYP2A6 mRNA]; NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of CYP2A6 protein]; NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of GSTA1 mRNA] |
CTD |
PMID:26879219 PMID:28555106 |
|
NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
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|
G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
EXP |
Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of NFKB1 mRNA] |
CTD |
PMID:34111468 |
|
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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|
G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
EXP |
[Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of NOS2 protein]; Linoleic Acid affects the reaction [Azoxymethane affects the expression of NOS2 protein] |
CTD |
PMID:22467055 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nos3 |
nitric oxide synthase 3 |
decreases expression |
ISO |
Linoleic Acid results in decreased expression of NOS3 mRNA |
CTD |
PMID:16895544 |
|
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
ISO |
Linoleic Acid metabolite results in increased expression of NQO1 mRNA |
CTD |
PMID:26879219 |
|
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr5a2 |
nuclear receptor subfamily 5, group A, member 2 |
multiple interactions |
ISO |
[NR5A2 gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Linoleic Acid analog |
CTD |
PMID:29515023 |
|
NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
multiple interactions |
ISO |
[Glucose deficiency co-treated with Linoleic Acid] results in increased expression of PCK1 mRNA |
CTD |
PMID:8536680 |
|
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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G |
Pdk4 |
pyruvate dehydrogenase kinase 4 |
increases expression |
EXP |
Linoleic Acid results in increased expression of PDK4 mRNA |
CTD |
PMID:23056435 |
|
NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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G |
Pld2 |
phospholipase D2 |
multiple interactions |
ISO |
PLD2 protein inhibits the reaction [Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased export of Cholesterol]]] |
CTD |
PMID:16118212 |
|
NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808
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G |
Plin1 |
perilipin 1 |
increases expression |
ISO |
Linoleic Acid analog results in increased expression of PLIN1 mRNA |
CTD |
PMID:27939595 |
|
NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
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G |
Pon1 |
paraoxonase 1 |
multiple interactions decreases activity |
ISO |
Linoleic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon]; Linoleic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid] Linoleic Acid results in decreased activity of PON1 protein |
CTD |
PMID:12871208 PMID:15375178 |
|
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions increases expression affects abundance increases activity affects binding |
ISO EXP |
[Bezafibrate binds to and results in increased activity of PPARA protein] which results in increased oxidation of Linoleic Acid; Linoleic Acid affects the reaction [PPARA protein binds to CREBBP protein]; Linoleic Acid binds to and results in increased activity of PPARA protein; Linoleic Acid promotes the reaction [PPARA protein binds to NCOA1 protein]; Linoleic Acid promotes the reaction [PPARA protein binds to NCOA2 protein] Linoleic Acid results in increased expression of PPARA mRNA PPARA protein affects the abundance of Linoleic Acid Diethylhexyl Phthalate inhibits the reaction [PPARA protein affects the abundance of Linoleic Acid]; Linoleic Acid binds to and results in increased activity of PPARA protein Linoleic Acid results in increased expression of PPARA mRNA; Linoleic Acid results in increased expression of PPARA protein Linoleic Acid results in increased activity of PPARA protein Linoleic Acid binds to PPARA protein |
CTD |
PMID:10403814 PMID:11172467 PMID:15491415 PMID:16731579 PMID:18154422 PMID:19263263 PMID:20404010 PMID:23056435 PMID:23619606 PMID:23843199 PMID:25786526 PMID:35752307 More...
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
multiple interactions decreases expression increases expression increases activity affects binding |
ISO EXP |
Linoleic Acid binds to and results in increased activity of PPARB protein Linoleic Acid results in decreased expression of PPARD mRNA Linoleic Acid results in increased expression of PPARD mRNA Linoleic Acid results in increased activity of PPARD protein Linoleic Acid binds to PPARB protein |
CTD |
PMID:11172467 PMID:15708366 PMID:16731579 PMID:23843199 PMID:25786526 |
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NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
affects binding multiple interactions increases expression increases activity decreases expression |
ISO EXP |
Linoleic Acid binds to PPARG protein Linoleic Acid binds to and results in increased activity of PPARG protein Linoleic Acid results in increased expression of PPARG mRNA resveratrol inhibits the reaction [Linoleic Acid results in increased expression of PPARG protein] Linoleic Acid results in increased activity of PPARG protein Linoleic Acid results in decreased expression of PPARG mRNA; Linoleic Acid results in decreased expression of PPARG protein |
CTD |
PMID:11172467 PMID:12021203 PMID:15708366 PMID:16731579 PMID:18154422 PMID:23843199 PMID:25672876 PMID:25786526 PMID:35752307 More...
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
increases expression |
EXP ISO |
Linoleic Acid results in increased expression of PPARGC1A mRNA |
CTD |
PMID:23056435 |
|
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Ppargc1b |
PPARG coactivator 1 beta |
increases expression |
EXP |
Linoleic Acid results in increased expression of PPARGC1B mRNA |
CTD |
PMID:23056435 |
|
NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression multiple interactions |
EXP ISO |
Linoleic Acid results in increased expression of PTGS2 mRNA Linoleic Acid inhibits the reaction [Benzo(a)pyrene results in increased expression of PTGS2 mRNA]; Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]]; Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA] |
CTD |
PMID:14563831 PMID:18001219 |
|
NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Rxra |
retinoid X receptor alpha |
affects binding multiple interactions |
ISO |
Linoleic Acid binds to RXRA protein Linoleic Acid binds to and results in increased activity of RXRA protein |
CTD |
PMID:16258897 PMID:16731579 |
|
NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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G |
Scd |
stearoyl-CoA desaturase |
multiple interactions increases expression |
ISO |
[Linoleic Acid co-treated with Testosterone] results in increased expression of SCD mRNA Linoleic Acid results in increased expression of SCD mRNA; Linoleic Acid results in increased expression of SCD protein |
CTD |
PMID:21457203 |
|
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Serpine1 |
serpin family E member 1 |
increases expression |
ISO |
Linoleic Acid results in increased expression of SERPINE1 mRNA |
CTD |
PMID:17374693 |
|
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Slc22a6 |
solute carrier family 22 member 6 |
decreases activity |
ISO |
Linoleic Acid results in decreased activity of SLC22A6 protein |
CTD |
PMID:29045746 |
|
NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
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G |
Slc22a8 |
solute carrier family 22 member 8 |
decreases activity |
ISO |
Linoleic Acid results in decreased activity of SLC22A8 protein |
CTD |
PMID:29045746 |
|
NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
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G |
Smad3 |
SMAD family member 3 |
decreases abundance |
ISO |
SMAD3 protein results in decreased abundance of Linoleic Acid |
CTD |
PMID:23034213 |
|
NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
decreases expression |
EXP |
Linoleic Acid results in decreased expression of SREBF1 mRNA |
CTD |
PMID:14563831 |
|
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
ISO |
TGFB1 protein promotes the reaction [Linoleic Acid results in increased activity of LOX protein] |
CTD |
PMID:26240151 |
|
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tnf |
tumor necrosis factor |
decreases response to substance multiple interactions |
ISO EXP |
Linoleic Acid results in decreased susceptibility to TNF protein Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of TNF mRNA] |
CTD |
PMID:22683933 PMID:34111468 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions |
ISO |
TRPV1 results in increased susceptibility to [Linoleic Acid co-treated with Freund's Adjuvant] |
CTD |
PMID:23006841 |
|
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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G |
Ucp2 |
uncoupling protein 2 |
increases expression |
EXP |
Linoleic Acid results in increased expression of UCP2 mRNA |
CTD |
PMID:11341955 |
|
NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
EXP |
[Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of VEGFA protein] |
CTD |
PMID:22467055 |
|
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Wnt10b |
Wnt family member 10B |
decreases expression |
ISO |
Linoleic Acid results in decreased expression of WNT10B mRNA |
CTD |
PMID:12021203 |
|
NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892
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|
|
G |
Abca1 |
ATP binding cassette subfamily A member 1 |
decreases expression |
ISO |
trilinolein results in decreased expression of ABCA1 mRNA |
CTD |
PMID:18356535 |
|
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcg5 |
ATP binding cassette subfamily G member 5 |
decreases expression |
ISO |
trilinolein results in decreased expression of ABCG5 mRNA |
CTD |
PMID:18356535 |
|
NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
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G |
Abcg8 |
ATP binding cassette subfamily G member 8 |
decreases expression |
ISO |
trilinolein results in decreased expression of ABCG8 mRNA |
CTD |
PMID:18356535 |
|
NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
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G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
decreases expression |
ISO |
trilinolein results in decreased expression of CYP27A1 mRNA |
CTD |
PMID:18356535 |
|
NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression |
ISO |
trilinolein results in increased expression of HMGCR mRNA |
CTD |
PMID:18356535 |
|
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Mttp |
microsomal triglyceride transfer protein |
increases expression |
ISO |
trilinolein results in increased expression of MTTP mRNA |
CTD |
PMID:18356535 |
|
NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
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G |
Npc1l1 |
NPC1 like intracellular cholesterol transporter 1 |
decreases expression |
ISO |
trilinolein results in decreased expression of NPC1L1 mRNA |
CTD |
PMID:18356535 |
|
NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113
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G |
Scd |
stearoyl-CoA desaturase |
multiple interactions decreases expression |
ISO |
Clofibrate inhibits the reaction [trilinolein results in decreased expression of SCD1 mRNA] |
CTD |
PMID:8790349 |
|
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Fech |
ferrochelatase |
affects abundance |
ISO |
FECH protein affects the abundance of 1-palmitoyl-2-linoleoylphosphatidylcholine |
CTD |
PMID:29906468 |
|
NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
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G |
Lipc |
lipase C, hepatic type |
decreases abundance |
ISO |
LIPC gene mutant form results in decreased abundance of 1-stearoyl-2-linoleoyl-sn-glycerol |
CTD |
PMID:24777581 |
|
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
decreases abundance |
ISO |
LIPG gene mutant form results in decreased abundance of 1-stearoyl-2-linoleoyl-sn-glycerol |
CTD |
PMID:24777581 |
|
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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G |
Cat |
catalase |
increases expression |
ISO |
13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of CAT protein |
CTD |
PMID:10946007 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav1 |
caveolin 1 |
increases expression |
ISO |
13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of CAV1 mRNA |
CTD |
PMID:27257344 |
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NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
EXP |
[13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of CCL2 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of CCL2 protein; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of CCL2 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of CCL2 protein |
CTD |
PMID:22135674 |
|
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Egr1 |
early growth response 1 |
multiple interactions |
EXP |
[13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of EGR1 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of EGR1 protein; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of EGR1 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of EGR1 protein |
CTD |
PMID:22135674 |
|
NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
increases expression |
EXP |
13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of PPARA protein |
CTD |
PMID:22135674 |
|
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression |
EXP |
13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of PPARG protein |
CTD |
PMID:22135674 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ephx3 |
epoxide hydrolase 3 |
multiple interactions |
ISO |
[EPHX3 gene mutant form results in decreased hydrolysis of Epoxy Compounds] results in decreased abundance of [9,10,13-trihydroxy-11-octadecenoic acid binds to Ceramides]; [EPHX3 gene mutant form results in decreased hydrolysis of Epoxy Compounds] which results in decreased chemical synthesis of 9,10,13-trihydroxy-11-octadecenoic acid |
CTD |
PMID:33334892 |
|
NCBI chr 7:11,206,812...11,212,122
Ensembl chr 7:11,206,812...11,212,122
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G |
Lipc |
lipase C, hepatic type |
multiple interactions |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl linoleate |
CTD |
PMID:24777581 |
|
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
multiple interactions affects abundance |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl linoleate LIPG gene mutant form affects the abundance of cholesteryl linoleate |
CTD |
PMID:24777581 |
|
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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|
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases activity |
ISO |
linoleamide analog results in increased activity of PPARG protein |
CTD |
PMID:29288688 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Agt |
angiotensinogen |
multiple interactions increases lipidation |
ISO |
Ascorbic Acid promotes the reaction [linoleic acid hydroperoxide results in increased lipidation of AGT protein modified form] |
CTD |
PMID:26111765 |
|
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Cygb |
cytoglobin |
increases metabolic processing |
EXP |
CYGB protein results in increased metabolism of linoleic acid hydroperoxide |
CTD |
PMID:11320098 |
|
NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
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G |
Gpx1 |
glutathione peroxidase 1 |
increases reduction |
ISO |
GPX1 protein results in increased reduction of linoleic acid hydroperoxide |
CTD |
PMID:8428933 |
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NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gpx2 |
glutathione peroxidase 2 |
increases reduction |
ISO |
GPX2 protein results in increased reduction of linoleic acid hydroperoxide |
CTD |
PMID:8428933 |
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NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
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G |
Iyd |
iodotyrosine deiodinase |
multiple interactions |
ISO |
methyl linoleate inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] |
CTD |
PMID:33352258 |
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NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
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G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCB11 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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G |
Abcb1b |
ATP-binding cassette, subfamily B (MDR/TAP), member 1B |
affects expression |
EXP |
Soybean Oil affects the expression of ABCB1B mRNA |
CTD |
PMID:15770074 |
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NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
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G |
Abcb4 |
ATP binding cassette subfamily B member 4 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCB4 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCC1 mRNA |
CTD |
PMID:15770074 |
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCC2 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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G |
Abcc5 |
ATP binding cassette subfamily C member 5 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCC5 mRNA |
CTD |
PMID:15770074 |
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NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
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G |
Abcc6 |
ATP binding cassette subfamily C member 6 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCC6 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
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G |
Acat1 |
acetyl-CoA acetyltransferase 1 |
decreases activity |
EXP |
Soybean Oil results in decreased activity of ACAT1 protein |
CTD |
PMID:12559476 |
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NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression |
EXP |
Soybean Oil results in increased expression of BCL2 protein |
CTD |
PMID:15309441 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Cat |
catalase |
increases activity |
EXP |
Soybean Oil results in increased activity of CAT protein |
CTD |
PMID:12781854 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccnd1 |
cyclin D1 |
increases expression |
EXP |
Soybean Oil results in increased expression of CCND1 mRNA |
CTD |
PMID:21088903 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
affects expression |
EXP |
Soybean Oil affects the expression of CYP4A1 mRNA |
CTD |
PMID:16079505 |
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NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
increases activity |
EXP |
Soybean Oil results in increased activity of CYP7A1 protein |
CTD |
PMID:12559476 |
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NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
EXP |
Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA]; Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein] |
CTD |
PMID:11600134 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases activity |
EXP |
Soybean Oil results in increased activity of HMGCR protein |
CTD |
PMID:12559476 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Il12b |
interleukin 12B |
decreases expression |
ISO |
Soybean Oil results in decreased expression of IL12B mRNA |
CTD |
PMID:10065739 |
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NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
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G |
Slc22a1 |
solute carrier family 22 member 1 |
affects expression |
EXP |
Soybean Oil affects the expression of SLC22A1 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
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G |
Slc22a7 |
solute carrier family 22 member 7 |
affects expression |
EXP |
Soybean Oil affects the expression of SLC22A7 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921
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