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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:testosterone
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Accession:CHEBI:17347 term browser browse the term
Definition:An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Synonyms:exact_synonym: 17beta-hydroxyandrost-4-en-3-one
 related_synonym: 17beta-Hydroxy-4-androsten-3-one;   4-androsten-17beta-ol-3-one;   Androderm;   Formula=C19H28O2;   InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1;   InChIKey=MUMGGOZAMZWBJJ-DYKIIFRCSA-N;   SMILES=[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@@H](O)CC[C@@]21[H];   Testosteron;   testosterona;   testosteronum
 alt_id: CHEBI:15214;   CHEBI:26883;   CHEBI:45798;   CHEBI:9461
 xref: Beilstein:1915399;   Beilstein:3653705;   CAS:58-22-0;   DrugBank:DB00624;   Drug_Central:2607;   Gmelin:538843;   HMDB:HMDB0000234;   KEGG:C00535;   KEGG:D00075;   KNApSAcK:C00003675;   LIPID_MAPS_instance:LMST02020002
 xref_mesh: MESH:D013739
 xref: PDBeChem:TES;   PMID:10438974;   PMID:11786693;   PMID:18900503;   PMID:24498482;   Reaxys:1915399;   Wikipedia:Testosterone



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testosterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B9D2 B9 domain containing 2 increases expression EXP Testosterone results in increased expression of TGFB1 mRNA CTD PMID:17157324 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885
JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 increases expression EXP Testosterone results in increased expression of KCND3 protein CTD PMID:17054656 NCBI chr17:63,470,829...63,668,354
Ensembl chr17:63,470,415...63,668,035
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 increases expression EXP Testosterone results in increased expression of KCNJ2 protein CTD PMID:17054656 NCBI chr 9:16,468,938...16,475,722
Ensembl chr 9:16,468,938...16,475,722
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 400
    chemical entity 402
      group 394
        organic group 311
          3-oxo-Delta(4)-steroid group 20
            3-oxo-Delta(4) steroid 20
              testosterone 3
                11-oxotestosterone 0
                11beta-hydroxytestosterone 0
                15alpha-hydroxytestosterone 0
                16alpha-hydroxytestosterone 0
                16beta-fluoro-17beta-hydroxyandrost-4-en-3-one propionate 0
                16beta-hydroxytestosterone 0
                19-hydroxytestosterone 0
                19-oxotestosterone 0
                1alpha-hydroxytestosterone 0
                1beta-hydroxytestosterone 0
                2-hydroxytestosterone + 0
                2alpha-fluoro-17beta-hydroxyandrost-4-en-3-one 0
                2alpha-hydroxytestosterone 0
                6-dehydrotestosterone + 0
                6beta-hydroxytestosterone + 0
                7alpha -hydroxytestosterone 0
                ethisterone 0
                glucosyltestosterone 0
                methyltestosterone 0
                testosterone 17-glucosiduronic acid 0
                testosterone 3-(O-carboxymethyl)oxime + 0
                testosterone acetate 0
                testosterone cypionate 0
                testosterone enanthate 0
                testosterone-3-CMO-Hist + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 400
    subatomic particle 400
      composite particle 402
        hadron 400
          baryon 400
            nucleon 400
              atomic nucleus 400
                atom 400
                  main group element atom 395
                    p-block element atom 395
                      carbon group element atom 382
                        carbon atom 383
                          organic molecular entity 381
                            organic group 311
                              organic divalent group 310
                                organodiyl group 310
                                  carbonyl group 310
                                    carbonyl compound 310
                                      ketone 48
                                        oxo steroid 23
                                          3-oxo steroid 21
                                            3-oxo-Delta(4) steroid 20
                                              testosterone 3
                                                11-oxotestosterone 0
                                                11beta-hydroxytestosterone 0
                                                15alpha-hydroxytestosterone 0
                                                16alpha-hydroxytestosterone 0
                                                16beta-fluoro-17beta-hydroxyandrost-4-en-3-one propionate 0
                                                16beta-hydroxytestosterone 0
                                                19-hydroxytestosterone 0
                                                19-oxotestosterone 0
                                                1alpha-hydroxytestosterone 0
                                                1beta-hydroxytestosterone 0
                                                2-hydroxytestosterone + 0
                                                2alpha-fluoro-17beta-hydroxyandrost-4-en-3-one 0
                                                2alpha-hydroxytestosterone 0
                                                6-dehydrotestosterone + 0
                                                6beta-hydroxytestosterone + 0
                                                7alpha -hydroxytestosterone 0
                                                ethisterone 0
                                                glucosyltestosterone 0
                                                methyltestosterone 0
                                                testosterone 17-glucosiduronic acid 0
                                                testosterone 3-(O-carboxymethyl)oxime + 0
                                                testosterone acetate 0
                                                testosterone cypionate 0
                                                testosterone enanthate 0
                                                testosterone-3-CMO-Hist + 0
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