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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:guanosine 5'-monophosphate
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Accession:CHEBI:17345 term browser browse the term
Definition:A purine ribonucleoside 5'-monophosphate having guanine as the nucleobase.
Synonyms:exact_synonym: 5'-guanylic acid;   [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen phosphate
 related_synonym: 5'-GMP;   Formula=C10H14N5O8P;   GMP;   Guanosine 5'-phosphate;   Guanosine monophosphate;   Guanylic acid;   InChI=1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1;   InChIKey=RQFCJASXJCIDSX-UUOKFMHZSA-N;   SMILES=Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O;   pG
 alt_id: CHEBI:13341;   CHEBI:14381;   CHEBI:24449;   CHEBI:24450;   CHEBI:40119;   CHEBI:42647;   CHEBI:42831;   CHEBI:42887;   CHEBI:42979;   CHEBI:47450;   CHEBI:5228
 xref: CAS:85-32-5;   DrugBank:DB01972;   HMDB:HMDB0001397;   KEGG:C00144;   KNApSAcK:C00019635
 xref_mesh: MESH:D006157
 xref: MetaCyc:GMP;   PDBeChem:5GP;   PMID:11233304;   PMID:11670950;   PMID:22735334;   PMID:2559771;   PMID:3569407;   Reaxys:59430;   Wikipedia:Guanosine_monophosphate
 cyclic_relationship: is_conjugate_acid_of CHEBI:58115



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guanosine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fut8 fucosyltransferase 8 decreases activity ISO Guanosine Monophosphate results in decreased activity of FUT8 protein CTD PMID:12770769 NCBI chr 6:95,948,230...96,176,677
Ensembl chr 6:95,949,991...96,176,677
JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase affects binding ISO Guanosine Monophosphate binds to GMDS protein CTD PMID:25526675 NCBI chr17:32,095,315...32,621,975
Ensembl chr17:32,095,386...32,621,961
JBrowse link
poly(guanylic acid) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP Poly G inhibits the reaction [Particulate Matter results in increased expression of ACTA2 mRNA]; Poly G inhibits the reaction [Particulate Matter results in increased expression of ACTA2 protein]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of ACTA2 mRNA]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of ACTA2 protein] CTD PMID:30391304 PMID:31028789 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions EXP Poly G inhibits the reaction [Silicon Dioxide results in increased expression of ATF6 protein] CTD PMID:31028789 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Casp12 caspase 12 multiple interactions EXP Poly G inhibits the reaction [Silicon Dioxide results in increased expression of CASP12 protein] CTD PMID:31028789 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Cdh1 cadherin 1 multiple interactions EXP Poly G inhibits the reaction [Particulate Matter results in decreased expression of CDH1 mRNA]; Poly G inhibits the reaction [Particulate Matter results in decreased expression of CDH1 protein]; Poly G inhibits the reaction [Silicon Dioxide results in decreased expression of CDH1 mRNA]; Poly G inhibits the reaction [Silicon Dioxide results in decreased expression of CDH1 protein] CTD PMID:30391304 PMID:31028789 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP Poly G inhibits the reaction [Particulate Matter results in increased expression of COL1A1 mRNA]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of COL1A1 mRNA] CTD PMID:30391304 PMID:31028789 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions EXP Poly G inhibits the reaction [Particulate Matter results in increased expression of COL3A1 mRNA]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of COL3A1 mRNA] CTD PMID:30391304 PMID:31028789 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP Poly G inhibits the reaction [Silicon Dioxide results in increased expression of DDIT3 protein] CTD PMID:31028789 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions EXP Poly G inhibits the reaction [Silicon Dioxide results in increased expression of ERN1 protein] CTD PMID:31028789 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP Poly G inhibits the reaction [Silicon Dioxide results in increased expression of HSPA5 protein] CTD PMID:31028789 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Marco macrophage receptor with collagenous structure multiple interactions ISO
EXP
Poly G inhibits the reaction [MARCO protein binds to and results in increased uptake of Polystyrenes]
Poly G inhibits the reaction [Particulate Matter results in increased expression of MARCO protein]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of MARCO protein]
CTD PMID:17361018 PMID:30391304 PMID:31028789 NCBI chr13:31,616,278...31,648,521
Ensembl chr13:31,616,278...31,648,521
JBrowse link
G Vim vimentin multiple interactions EXP Poly G inhibits the reaction [Particulate Matter results in increased expression of VIM mRNA]; Poly G inhibits the reaction [Particulate Matter results in increased expression of VIM protein]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of VIM mRNA]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of VIM protein] CTD PMID:30391304 PMID:31028789 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    role 20008
      biological role 20007
        biochemical role 19640
          metabolite 19623
            guanosine 5'-monophosphate 13
              (R)-lipoyl-GMP 0
              2'-O-methylguanosine 5'-monophosphate + 0
              4-demethylwyosine 5'-monophosphate + 0
              7-methylguanosine 5'-phosphate(1+) 0
              8-oxo-GMP 0
              GMP 3'-end residue + 11
              GMP 5'-end residue + 11
              N(1)-methylguanosine 5'-monophosphate + 0
              N(2),N(2),N(7)-trimethylguanosine 5'-phosphate 0
              N(2),N(2)-dimethylguanosine 5'-monophosphate + 0
              N(2)-methylguanosine 5'-monophosphate + 0
              N(6)-(5'-guanylyl)-L-lysine 0
              N(7)-methylguanosine 5'-phosphate + 0
              N(epsilon)-(5'-guanylyl)-N(alpha)-acetyl-L-lysine methyl ester(1-) 0
              N(epsilon)-GMP-N(alpha)-acetyl-L-lysine methyl ester 0
              beta-hydroxywybutosine 5'-monophosphate + 0
              coenzyme F390-G 0
              ddhGMP 0
              guanosine 5'-monophosphate residue + 11
              wybutosine 5'-monophosphate + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      chalcogen 19693
                        oxygen atom 19666
                          oxygen molecular entity 19666
                            hydroxides 19412
                              oxoacid 18715
                                pnictogen oxoacid 11007
                                  phosphorus oxoacid 9812
                                    phosphoric acids 8640
                                      phosphoric acid 8640
                                        phosphoric acid derivative 8344
                                          phosphate 8344
                                            organic phosphate 8343
                                              carbohydrate phosphate 1831
                                                phospho sugar 1679
                                                  aldose phosphate 1677
                                                    aldopentose phosphate 1669
                                                      ribose phosphate 1664
                                                        ribonucleotide 1623
                                                          purine ribonucleotide 1596
                                                            guanyl ribonucleotide 140
                                                              guanosine phosphate 71
                                                                guanosine 5'-phosphate 71
                                                                  guanosine 5'-monophosphate 13
                                                                    (R)-lipoyl-GMP 0
                                                                    2'-O-methylguanosine 5'-monophosphate + 0
                                                                    4-demethylwyosine 5'-monophosphate + 0
                                                                    7-methylguanosine 5'-phosphate(1+) 0
                                                                    8-oxo-GMP 0
                                                                    GMP 3'-end residue + 11
                                                                    GMP 5'-end residue + 11
                                                                    N(1)-methylguanosine 5'-monophosphate + 0
                                                                    N(2),N(2),N(7)-trimethylguanosine 5'-phosphate 0
                                                                    N(2),N(2)-dimethylguanosine 5'-monophosphate + 0
                                                                    N(2)-methylguanosine 5'-monophosphate + 0
                                                                    N(6)-(5'-guanylyl)-L-lysine 0
                                                                    N(7)-methylguanosine 5'-phosphate + 0
                                                                    N(epsilon)-(5'-guanylyl)-N(alpha)-acetyl-L-lysine methyl ester(1-) 0
                                                                    N(epsilon)-GMP-N(alpha)-acetyl-L-lysine methyl ester 0
                                                                    beta-hydroxywybutosine 5'-monophosphate + 0
                                                                    coenzyme F390-G 0
                                                                    ddhGMP 0
                                                                    guanosine 5'-monophosphate residue + 11
                                                                    wybutosine 5'-monophosphate + 0
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