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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Ethyl pyruvate
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Accession:CHEBI:173421 term browser browse the term
Synonyms:exact_synonym: ethyl 2-oxopropanoate
 related_synonym: Formula=C5H8O3;   InChI=1S/C5H8O3/c1-3-8-5(7)4(2)6/h3H2,1-2H3;   InChIKey=XXRCUYVCPSWGCC-UHFFFAOYSA-N;   SMILES=O(CC)C(=O)C(=O)C
 xref: CAS:617-35-6;   Chemspider:11544;   DrugBank:DB05869;   HMDB:HMDB0031643
 xref_mesh: MESH:C046522
 xref: PDBeChem:9X7


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Ethyl pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO ethyl pyruvate inhibits the reaction [Dust results in increased expression of AGER protein] CTD PMID:30859215 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO ethyl pyruvate inhibits the reaction [Acetaminophen results in increased secretion of HMGB1 protein]; ethyl pyruvate inhibits the reaction [Dust affects the localization of HMGB1 protein] CTD PMID:21513726 PMID:30859215 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Il6 interleukin 6 multiple interactions ISO ethyl pyruvate inhibits the reaction [Dust results in increased expression of and results in increased secretion of IL6 protein] CTD PMID:30859215 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP
ISO
ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK1 protein]
ethyl pyruvate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]
CTD PMID:21316417 PMID:21818760 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP
ISO
ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK3 protein]
ethyl pyruvate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]
CTD PMID:21316417 PMID:21818760 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK8 protein] CTD PMID:21818760 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions EXP ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK9 protein] CTD PMID:21818760 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO ethyl pyruvate inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of MMP9 protein]; ethyl pyruvate inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA] CTD PMID:21316417 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP
ethyl pyruvate inhibits the reaction [Phosgene results in increased expression of NOS2 protein] CTD PMID:21818760 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO
ethyl pyruvate inhibits the reaction [Phosgene results in increased expression of PTGS2 protein] CTD PMID:21818760 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO ethyl pyruvate inhibits the reaction [Dust results in increased expression of and results in increased secretion of TNF protein]; ethyl pyruvate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:21316417 PMID:30859215 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      chemical role 19345
        donor 18654
          Bronsted acid 18537
            oxoacid 18498
              carbon oxoacid 18378
                carboxylic acid 18373
                  oxo carboxylic acid 6294
                    Ethyl pyruvate 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic acid 18373
                                        oxo carboxylic acid 6294
                                          Ethyl pyruvate 11
paths to the root