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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:penicillin
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Accession:CHEBI:17334 term browser browse the term
Definition:Any member of the group of substituted penams containing two methyl substituents at position 2, a carboxylate substituent at position 3 and a carboxamido group at position 6.
Synonyms:related_synonym: Formula=C9H11N2O4SR;   SMILES=[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC([*])=O)C(O)=O;   penicillins
 alt_id: CHEBI:14742;   CHEBI:25869;   CHEBI:7961
 xref: KEGG:C00395;   PMID:11851248;   PMID:12833570;   PMID:1502708;   PMID:16033609;   PMID:7061385;   PMID:7798534;   Wikipedia:Penicillin
 cyclic_relationship: is_conjugate_acid_of CHEBI:51356


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amoxicillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Amoxicillin results in increased expression of AKR1B10 mRNA CTD PMID:28444390 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Aqp5 aquaporin 5 decreases expression EXP Amoxicillin results in decreased expression of AQP5 protein CTD PMID:30031112 NCBI chr 7:141,249,044...141,252,576
Ensembl chr 7:141,249,044...141,252,578
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression ISO Amoxicillin results in decreased expression of CXCL10 mRNA CTD PMID:25091725 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 increases expression ISO Amoxicillin results in increased expression of CYP11B2 CTD PMID:17822730 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression ISO Amoxicillin results in increased expression of CYP19A1 CTD PMID:17822730 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 multiple interactions
decreases activity
ISO Amoxicillin inhibits the reaction [CYP2C8 protein results in decreased methylation of Aminopyrine]
Amoxicillin results in decreased activity of CYP2C8 protein
CTD PMID:26763401 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Gsr glutathione-disulfide reductase decreases activity ISO Amoxicillin results in decreased activity of GSR protein CTD PMID:32196862 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Amoxicillin results in increased expression of NQO1 mRNA CTD PMID:28444390 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G RT1-Bb RT1 class II, locus Bb affects expression ISO Amoxicillin affects the expression of HLA-DQB1 mRNA CTD PMID:25811541 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Amoxicillin results in increased expression of SRXN1 mRNA CTD PMID:28444390 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
ampicillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression ISO Ampicillin results in decreased expression of ABCC3 mRNA CTD PMID:21632981 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases transport ISO ABCC4 protein results in increased transport of Ampicillin CTD PMID:17939016 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ACAT2 protein CTD PMID:30545405 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Acat2l1 acetyl-CoA acetyltransferase 2-like 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ACAT2L1 protein CTD PMID:30545405 NCBI chr 1:48,008,574...48,025,730
Ensembl chr 1:47,996,521...48,026,268
JBrowse link
G Ace2 angiotensin I converting enzyme 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ACE2 protein CTD PMID:30545405 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Ager advanced glycosylation end product-specific receptor decreases expression ISO Ampicillin results in decreased expression of AGER mRNA CTD PMID:24747151 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Ahsg alpha-2-HS-glycoprotein multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of AHSG protein CTD PMID:30545405 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 decreases expression ISO Ampicillin results in decreased expression of AKR1B10 mRNA CTD PMID:21632981, PMID:26198647 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases expression ISO Ampicillin results in decreased expression of AKR1C2 mRNA CTD PMID:21632981 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ALDOA protein CTD PMID:30545405 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Aldob aldolase, fructose-bisphosphate B multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ALDOB protein CTD PMID:30545405 NCBI chr 5:64,805,772...64,818,813
Ensembl chr 5:64,805,773...64,818,824
JBrowse link
G Amot angiomotin increases expression ISO Ampicillin results in increased expression of AMOT mRNA CTD PMID:21632981 NCBI chr  X:116,751,231...116,810,238
Ensembl chr  X:116,751,230...116,792,864
JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression ISO Ampicillin results in increased expression of ANKRD1 mRNA CTD PMID:21632981 NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression ISO Ampicillin results in decreased expression of AQP3 mRNA CTD PMID:21632981 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Arg1 arginase 1 increases expression ISO Ampicillin results in increased expression of ARG1 mRNA CTD PMID:21632981 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arg2 arginase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of ARG2 protein CTD PMID:30545405 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha increases expression ISO Ampicillin results in increased expression of ARHGDIA mRNA CTD PMID:21632981 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arpc3 actin related protein 2/3 complex, subunit 3 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ARPC3 protein CTD PMID:30545405 NCBI chr12:39,653,951...39,667,817
Ensembl chr12:39,653,953...39,667,849
JBrowse link
G Arrdc3 arrestin domain containing 3 decreases expression ISO Ampicillin results in decreased expression of ARRDC3 mRNA CTD PMID:21632981 NCBI chr 2:8,732,907...8,745,445
Ensembl chr 2:8,732,932...8,743,069
JBrowse link
G Arrdc4 arrestin domain containing 4 decreases expression ISO Ampicillin results in decreased expression of ARRDC4 mRNA CTD PMID:21632981 NCBI chr 1:129,766,097...129,780,076
Ensembl chr 1:129,766,100...129,780,356
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of ASAH1 protein CTD PMID:30545405 NCBI chr16:53,998,604...54,030,006
Ensembl chr16:53,998,560...54,040,836
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Ampicillin results in decreased expression of ASNS mRNA CTD PMID:21632981 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP1A1 protein CTD PMID:30545405 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP2A3 protein CTD PMID:30545405 NCBI chr10:59,528,849...59,560,440
Ensembl chr10:59,529,785...59,560,433
JBrowse link
G Atp5mf ATP synthase membrane subunit f multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP5J2 protein CTD PMID:30545405 NCBI chr12:11,191,799...11,198,369
Ensembl chr12:11,191,812...11,198,369
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP5H protein CTD PMID:30545405 NCBI chr10:103,967,340...103,972,552
Ensembl chr10:103,967,312...103,972,668
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP5J protein CTD PMID:30545405 NCBI chr11:24,286,806...24,294,419
Ensembl chr11:24,286,787...24,294,179
JBrowse link
G B3galt5 Beta-1,3-galactosyltransferase 5 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of B3GALT5 protein CTD PMID:30545405 NCBI chr11:36,638,067...36,683,915
Ensembl chr11:36,634,662...36,683,672
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases response to substance ISO BAX results in increased susceptibility to Ampicillin CTD PMID:15731293 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bpifb2 BPI fold containing family B, member 2 increases expression ISO Ampicillin results in increased expression of BPIFB2 mRNA CTD PMID:21632981 NCBI chr 3:149,358,881...149,377,867
Ensembl chr 3:149,358,881...149,377,867
JBrowse link
G Ca9 carbonic anhydrase 9 increases expression ISO Ampicillin results in increased expression of CA9 mRNA CTD PMID:21632981 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Calr calreticulin increases expression ISO Ampicillin results in increased expression of CALR mRNA CTD PMID:21632981 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO Ampicillin results in increased expression of CCN1 mRNA CTD PMID:21632981 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccpg1 cell cycle progression 1 decreases expression ISO Ampicillin results in decreased expression of CCPG1 mRNA CTD PMID:21632981 NCBI chr 8:79,660,634...79,692,044
Ensembl chr 8:79,660,657...79,692,039
JBrowse link
G Cd40 CD40 molecule increases expression ISO Ampicillin results in increased expression of CD40 mRNA CTD PMID:25091725 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Ampicillin results in increased expression of CES1 mRNA CTD PMID:22609641 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Chst15 carbohydrate sulfotransferase 15 increases expression ISO Ampicillin results in increased expression of CHST15 mRNA CTD PMID:21632981 NCBI chr 1:204,243,396...204,328,960
Ensembl chr 1:204,245,645...204,322,544
JBrowse link
G Ckb creatine kinase B increases expression ISO Ampicillin results in increased expression of CKB mRNA CTD PMID:21632981 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Clca4 chloride channel accessory 4 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of CLCA4 protein CTD PMID:30545405 NCBI chr 2:250,842,939...250,864,060
Ensembl chr 2:250,843,165...250,862,419
JBrowse link
G Cldn7 claudin 7 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of CLDN7 protein CTD PMID:30545405 NCBI chr10:56,576,326...56,578,632
Ensembl chr10:56,576,428...56,578,626
JBrowse link
G Clgn calmegin decreases expression ISO Ampicillin results in decreased expression of CLGN mRNA CTD PMID:21632981 NCBI chr19:24,545,257...24,578,527
Ensembl chr19:24,545,318...24,576,798
JBrowse link
G Clic3 chloride intracellular channel 3 increases expression ISO Ampicillin results in increased expression of CLIC3 mRNA CTD PMID:21632981 NCBI chr 3:2,675,732...2,678,248
Ensembl chr 3:2,676,296...2,680,565
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CMBL protein CTD PMID:30545405 NCBI chr 2:84,645,084...84,666,836
Ensembl chr 2:84,645,084...84,666,835
JBrowse link
G Cndp2 carnosine dipeptidase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of CNDP2 protein CTD PMID:30545405 NCBI chr18:81,521,966...81,539,065
Ensembl chr18:81,521,968...81,539,065
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of COX5A protein CTD PMID:30545405 NCBI chr 8:62,298,358...62,309,765
Ensembl chr 8:62,298,358...62,309,765
JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of COX6B1 protein CTD PMID:30545405 NCBI chr 1:89,075,987...89,084,834
Ensembl chr 1:89,075,975...89,084,859
Ensembl chr 2:89,075,975...89,084,859
JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of COX7A2 protein CTD PMID:30545405 NCBI chr 8:87,209,529...87,213,627
Ensembl chr 8:87,209,530...87,213,627
JBrowse link
G Cp ceruloplasmin increases expression ISO Ampicillin results in increased expression of CP mRNA CTD PMID:21632981 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 decreases expression ISO Ampicillin results in decreased expression of CREB3L3 mRNA CTD PMID:21632981 NCBI chr 7:11,490,852...11,499,287
Ensembl chr 7:11,490,852...11,499,282
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of CSF2 protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of CSF2 protein CTD PMID:31442584 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csta cystatin A decreases expression ISO Ampicillin results in decreased expression of CSTA mRNA CTD PMID:21632981 NCBI chr11:67,555,792...67,566,980
Ensembl chr11:67,555,658...67,566,972
JBrowse link
G Ctsa cathepsin A multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CTSA protein CTD PMID:30545405 NCBI chr 3:161,298,750...161,304,627
Ensembl chr 3:161,298,962...161,304,625
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO Ampicillin results in increased expression of CXCL2 mRNA CTD PMID:24747151 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO Ampicillin results in decreased expression of CYP1A1 mRNA CTD PMID:21632981 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP1A2 mRNA CTD PMID:30545405 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 decreases expression ISO Ampicillin results in decreased expression of CYP24A1 mRNA CTD PMID:21632981 NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2C11 mRNA CTD PMID:30545405 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2D2 mRNA CTD PMID:30545405 NCBI chr 7:123,651,827...123,655,896
Ensembl chr 7:123,651,827...123,655,896
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2E1 mRNA CTD PMID:30545405 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP3A2 mRNA CTD PMID:30545405 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression ISO Ampicillin results in increased expression of DKK1 mRNA CTD PMID:21632981 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Ampicillin results in increased expression of DUSP1 mRNA CTD PMID:21632981 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp7 dual specificity phosphatase 7 increases expression ISO Ampicillin results in increased expression of DUSP7 mRNA CTD PMID:21632981 NCBI chr 8:115,069,095...115,076,130
Ensembl chr 8:115,069,095...115,076,130
JBrowse link
G Edn1 endothelin 1 increases expression ISO Ampicillin results in increased expression of EDN1 mRNA CTD PMID:21632981 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Epcam epithelial cell adhesion molecule multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of EPCAM protein CTD PMID:30545405 NCBI chr 6:11,282,194...11,308,870
Ensembl chr 6:11,281,964...11,298,216
JBrowse link
G Esm1 endothelial cell-specific molecule 1 decreases expression ISO Ampicillin results in decreased expression of ESM1 mRNA CTD PMID:21632981 NCBI chr 2:45,104,392...45,113,130
Ensembl chr 2:45,104,305...45,113,131
JBrowse link
G Etfa electron transfer flavoprotein subunit alpha multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ETFA protein CTD PMID:30545405 NCBI chr 8:60,028,786...60,086,352
Ensembl chr 8:60,028,789...60,086,403
JBrowse link
G Ezr ezrin multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of EZR protein CTD PMID:30545405 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G Filip1l filamin A interacting protein 1-like increases expression ISO Ampicillin results in increased expression of FILIP1L mRNA CTD PMID:21632981 NCBI chr11:45,039,488...45,275,141
Ensembl chr11:45,039,461...45,124,423
JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 increases expression ISO Ampicillin results in increased expression of FXYD1 mRNA CTD PMID:21632981 NCBI chr 1:89,484,197...89,488,279
Ensembl chr 1:89,484,199...89,488,223
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Ampicillin results in decreased expression of GCLC mRNA CTD PMID:21632981, PMID:26198647 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit decreases expression
increases expression
ISO Ampicillin results in decreased expression of GCLM mRNA
Ampicillin results in increased expression of GCLM mRNA
CTD PMID:21632981, PMID:22609641 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of GFPT2 protein CTD PMID:30545405 NCBI chr10:35,279,237...35,325,506
Ensembl chr10:35,279,236...35,325,508
JBrowse link
G Gipc2 GIPC PDZ domain containing family, member 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of GIPC2 protein CTD PMID:30545405 NCBI chr 2:257,293,161...257,377,982
Ensembl chr 2:257,293,167...257,376,756
JBrowse link
G Gng12 G protein subunit gamma 12 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of GNG12 protein CTD PMID:30545405 NCBI chr 4:97,634,925...97,763,478
Ensembl chr 4:97,657,671...97,760,102
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 decreases expression ISO Ampicillin results in decreased expression of GPAT3 mRNA CTD PMID:21632981, PMID:26198647 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of GPX1 protein CTD PMID:30545405 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of GSTM2 mRNA CTD PMID:30545405 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of HEXB protein CTD PMID:30545405 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Hmgb1 high mobility group box 1 increases expression ISO Ampicillin results in increased expression of HMGB1 protein CTD PMID:24747151 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Ampicillin results in increased expression of HMOX1 mRNA CTD PMID:25091725 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of HNRNPH2 protein CTD PMID:30545405 NCBI chr  X:105,417,603...105,423,531
Ensembl chr  X:105,419,285...105,422,861
JBrowse link
G Hoxd1 homeo box D1 increases expression ISO Ampicillin results in increased expression of HOXD1 mRNA CTD PMID:21632981 NCBI chr 3:61,685,619...61,687,758
Ensembl chr 3:61,685,619...61,687,758
JBrowse link
G Hp haptoglobin multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of HP protein CTD PMID:30545405 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Ampicillin results in decreased expression of IFRD1 mRNA CTD PMID:21632981 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression ISO Ampicillin results in increased expression of IGFBP3 mRNA CTD PMID:21632981 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
EXP
ISO
Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]
Ampicillin results in increased expression of IL1B mRNA
CTD PMID:21893697, PMID:24747151 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of IL6 protein; Dextran Sulfate inhibits the reaction [[Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of IL6 protein] CTD PMID:31442584 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jdp2 Jun dimerization protein 2 decreases expression ISO Ampicillin results in decreased expression of JDP2 mRNA CTD PMID:21632981 NCBI chr 6:109,464,910...109,505,591
Ensembl chr 6:109,466,060...109,505,161
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression ISO Ampicillin results in increased expression of JUND mRNA CTD PMID:21632981 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
JBrowse link
G Kng2 kininogen 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of MAP1 protein CTD PMID:30545405 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Krt16 keratin 16 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of KRT16 protein CTD PMID:30545405 NCBI chr10:88,149,210...88,152,167
Ensembl chr10:88,149,345...88,152,064
JBrowse link
G Lox lysyl oxidase increases expression ISO Ampicillin results in increased expression of LOX mRNA CTD PMID:21632981 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Lyz2 lysozyme 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of LYZ2 protein CTD PMID:30545405 NCBI chr 7:60,335,968...60,341,264
Ensembl chr 7:60,335,969...60,341,264
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of MAPK3 protein CTD PMID:30545405 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Maz MYC associated zinc finger protein increases expression ISO Ampicillin results in increased expression of MAZ mRNA CTD PMID:21632981 NCBI chr 1:198,456,699...198,460,126
Ensembl chr 1:198,456,699...198,460,126
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Ampicillin inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11686837, PMID:11991626, PMID:18306037 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mtss2 MTSS I-BAR domain containing 2 increases expression ISO Ampicillin results in increased expression of MTSS2 mRNA CTD PMID:21632981 NCBI chr19:40,904,779...40,925,660
Ensembl chr19:40,905,847...40,925,660
JBrowse link
G Myh14 myosin heavy chain 14 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of MYH14 protein CTD PMID:30545405 NCBI chr 1:100,608,975...100,671,086
Ensembl chr 1:100,608,966...100,671,074
JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of NDUFA13 protein CTD PMID:30545405 NCBI chr16:21,275,311...21,282,246
Ensembl chr16:21,275,311...21,282,246
JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of NDUFAB1 protein CTD PMID:30545405 NCBI chr 1:192,044,209...192,057,644
Ensembl chr 1:192,044,216...192,057,612
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Ampicillin inhibits the reaction [Indomethacin results in increased activity of NOS2 protein]; Ampicillin inhibits the reaction [Indomethacin results in increased expression of NOS2 mRNA] CTD PMID:11686837, PMID:12568917, PMID:15610444, PMID:16944022, PMID:18306037, PMID:21893697 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of NPC2 protein CTD PMID:30545405 NCBI chr 6:108,467,410...108,488,330
Ensembl chr 6:108,467,410...108,488,330
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Ampicillin results in increased expression of NQO1 mRNA CTD PMID:22609641 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pa2g4 proliferation-associated 2G4 increases expression ISO Ampicillin results in increased expression of PA2G4 mRNA CTD PMID:21632981 NCBI chr 7:2,979,587...2,987,055
Ensembl chr 7:2,979,588...2,987,055
JBrowse link
G Pabpc1l poly(A) binding protein, cytoplasmic 1-like decreases expression ISO Ampicillin results in decreased expression of PABPC1L mRNA CTD PMID:21632981 NCBI chr 3:160,410,733...160,447,073
Ensembl chr 3:160,410,757...160,444,940
JBrowse link
G Pdp2 pyruvate dehyrogenase phosphatase catalytic subunit 2 increases expression ISO Ampicillin results in increased expression of PDP2 mRNA CTD PMID:21632981 NCBI chr19:597,427...601,556
Ensembl chr19:597,427...601,469
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 increases expression ISO Ampicillin results in increased expression of PFKFB3 mRNA CTD PMID:21632981 NCBI chr17:70,632,778...70,713,736
Ensembl chr17:70,684,134...70,713,726
JBrowse link
G Pfn1 profilin 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PFN1 protein CTD PMID:30545405 NCBI chr10:57,273,003...57,275,708
Ensembl chr10:57,273,005...57,275,708
JBrowse link
G Pgam1 phosphoglycerate mutase 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PGAM1 protein CTD PMID:30545405 NCBI chr 1:261,158,204...261,165,814
Ensembl chr 1:261,158,261...261,165,808
JBrowse link
G Pgc progastricsin increases expression ISO Ampicillin results in increased expression of PGC mRNA CTD PMID:21632981 NCBI chr 9:15,266,699...15,274,917
Ensembl chr 9:15,266,699...15,274,917
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity EXP Ampicillin results in decreased activity of PGD protein CTD PMID:15558954 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pir pirin increases expression ISO Ampicillin results in increased expression of PIR mRNA CTD PMID:22609641 NCBI chr  X:31,852,322...31,968,152
Ensembl chr  X:31,852,323...31,968,152
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression ISO Ampicillin results in increased expression of PKM mRNA CTD PMID:21632981 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722
JBrowse link
G Plppr1 phospholipid phosphatase related 1 increases expression ISO Ampicillin results in increased expression of PLPPR1 mRNA CTD PMID:21632981 NCBI chr 5:67,852,817...67,985,310
Ensembl chr 5:67,852,180...68,139,199
JBrowse link
G Pmm2 phosphomannomutase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PMM2 protein CTD PMID:30545405 NCBI chr10:7,056,258...7,077,443
Ensembl chr10:7,056,266...7,077,443
JBrowse link
G Pon1 paraoxonase 1 decreases activity ISO Ampicillin results in decreased activity of PON1 protein CTD PMID:16880604, PMID:31581362 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PPP1CA protein CTD PMID:30545405 NCBI chr 1:219,439,953...219,443,570
Ensembl chr 1:219,439,953...219,443,570
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PPP1CB protein CTD PMID:30545405 NCBI chr 6:23,548,507...23,581,136
Ensembl chr 6:23,549,317...23,581,052
JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PPP1CC protein CTD PMID:30545405 NCBI chr12:39,864,302...39,882,030
Ensembl chr12:39,864,295...39,882,030
JBrowse link
G Psma3 proteasome 20S subunit alpha 3 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of PSMA3 protein CTD PMID:30545405 NCBI chr 6:93,423,029...93,444,223
Ensembl chr 6:93,423,002...93,444,240
JBrowse link
G Ptgr1 prostaglandin reductase 1 decreases expression ISO Ampicillin results in decreased expression of PTGR1 mRNA CTD PMID:21632981 NCBI chr 5:76,110,746...76,129,361
Ensembl chr 5:76,110,738...76,129,441
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Ampicillin inhibits the reaction [SC 560 results in increased expression of PTGS2 mRNA] CTD PMID:15610444, PMID:21893697 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptms parathymosin increases expression ISO Ampicillin results in increased expression of PTMS mRNA CTD PMID:21632981 NCBI chr 4:157,435,371...157,439,507
Ensembl chr 4:157,435,373...157,439,507
JBrowse link
G Ralb RAS like proto-oncogene B multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of RALB protein CTD PMID:30545405 NCBI chr13:35,494,716...35,531,503
Ensembl chr13:35,494,721...35,511,020
JBrowse link
G Ran RAN, member RAS oncogene family multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RAN protein CTD PMID:30545405 NCBI chr12:31,319,556...31,324,105
Ensembl chr12:31,320,624...31,323,810
JBrowse link
G Rgcc regulator of cell cycle increases expression ISO Ampicillin results in increased expression of RGCC mRNA CTD PMID:21632981 NCBI chr15:61,551,861...61,564,695
Ensembl chr15:61,551,861...61,564,695
JBrowse link
G Rida reactive intermediate imine deaminase A homolog multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of RIDA protein CTD PMID:30545405 NCBI chr 7:73,256,506...73,270,308
Ensembl chr 7:73,256,508...73,270,308
JBrowse link
G Rpl30 ribosomal protein L30 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPL30 protein CTD PMID:30545405 NCBI chr 7:73,213,538...73,216,431
Ensembl chr 7:73,213,581...73,216,251
JBrowse link
G Rpn2 ribophorin II multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPN2 protein CTD PMID:30545405 NCBI chr 3:153,398,373...153,445,633
Ensembl chr 3:153,398,130...153,445,632
JBrowse link
G Rps23 ribosomal protein S23 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPS23 protein CTD PMID:30545405 NCBI chr 2:19,823,234...19,824,804
Ensembl chr 2:19,823,234...19,824,804
JBrowse link
G Rps27l ribosomal protein S27-like multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPS27L protein CTD PMID:30545405 NCBI chr 8:72,741,155...72,746,090
Ensembl chr 8:72,741,155...72,746,090
JBrowse link
G RT1-DMb RT1 class II, locus DMb multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of RT1-DMB protein CTD PMID:30545405 NCBI chr20:3,945,383...3,952,838
Ensembl chr20:5,227,045...5,234,290
JBrowse link
G S100a10 S100 calcium binding protein A10 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of S100A10 protein CTD PMID:30545405 NCBI chr 2:193,892,589...193,901,236
Ensembl chr 2:193,892,589...193,901,236
JBrowse link
G S100a11 S100 calcium binding protein A11 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of S100A11 protein CTD PMID:30545405 NCBI chr 2:193,863,185...193,868,646
Ensembl chr 2:193,866,951...193,868,502
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Ampicillin results in increased expression of S100A9 mRNA CTD PMID:24747151 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G Samd1 sterile alpha motif domain containing 1 increases expression ISO Ampicillin results in increased expression of SAMD1 mRNA CTD PMID:21632981 NCBI chr19:25,119,560...25,122,781
Ensembl chr19:25,120,128...25,122,233
JBrowse link
G Scarb2 scavenger receptor class B, member 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of SCARB2 protein CTD PMID:30545405 NCBI chr14:17,064,173...17,115,620
Ensembl chr14:17,064,353...17,115,963
JBrowse link
G Serpinb6a serpin family B member 6A multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SERPINB6 protein CTD PMID:30545405 NCBI chr17:32,154,747...32,209,598
Ensembl chr17:32,190,801...32,209,590
JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 decreases expression ISO Ampicillin results in decreased expression of SGK2 mRNA CTD PMID:21632981 NCBI chr 3:159,361,313...159,385,843
Ensembl chr 3:159,368,273...159,384,775
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SHMT2 protein CTD PMID:30545405 NCBI chr 7:70,824,718...70,829,822
Ensembl chr 7:70,824,715...70,829,815
JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression ISO Ampicillin results in increased expression of SLC1A2 protein CTD PMID:17138558 NCBI chr 3:92,518,679...92,665,731
Ensembl chr 3:92,640,752...92,665,644
JBrowse link
G Slc22a15 solute carrier family 22, member 15 decreases expression ISO Ampicillin results in decreased expression of SLC22A15 mRNA CTD PMID:21632981 NCBI chr 2:204,281,638...204,344,026
Ensembl chr 2:204,281,638...204,341,676
JBrowse link
G Slc25a20 solute carrier family 25 member 20 multiple interactions EXP Ampicillin binds to and results in decreased activity of SLC25A20 protein; Ampicillin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine] CTD PMID:18452908 NCBI chr 8:117,455,308...117,476,762
Ensembl chr 8:117,455,262...117,476,734
JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression ISO Ampicillin results in increased expression of SLC2A3 mRNA CTD PMID:21632981 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Slc3a1 solute carrier family 3 member 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SLC3A1 protein CTD PMID:30545405 NCBI chr 6:8,284,937...8,318,649
Ensembl chr 6:8,284,878...8,318,674
JBrowse link
G Slc6a14 solute carrier family 6 member 14 increases expression ISO Ampicillin results in increased expression of SLC6A14 mRNA CTD PMID:21632981 NCBI chr  X:120,624,522...120,647,964
Ensembl chr  X:120,624,518...120,649,111
JBrowse link
G Slc6a8 solute carrier family 6 member 8 increases expression ISO Ampicillin results in increased expression of SLC6A8 mRNA CTD PMID:21632981 NCBI chr  X:157,129,987...157,139,321
Ensembl chr  X:157,129,987...157,139,291
JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression ISO Ampicillin results in decreased expression of SLC7A11 mRNA CTD PMID:21632981, PMID:26198647 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slc9a3r2 SLC9A3 regulator 2 increases expression ISO Ampicillin results in increased expression of SLC9A3R2 mRNA CTD PMID:21632981 NCBI chr10:14,003,330...14,015,066
Ensembl chr10:14,003,320...14,013,870
JBrowse link
G Smim14 small integral membrane protein 14 decreases expression ISO Ampicillin results in decreased expression of SMIM14 mRNA CTD PMID:21632981 NCBI chr14:44,413,636...44,460,044
Ensembl chr14:44,413,636...44,457,239
JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SMPD2 protein CTD PMID:30545405 NCBI chr20:46,212,070...46,215,183
Ensembl chr20:46,211,892...46,215,120
JBrowse link
G Srxn1 sulfiredoxin 1 decreases expression ISO Ampicillin results in decreased expression of SRXN1 mRNA CTD PMID:21632981, PMID:26198647 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Tagln transgelin increases expression ISO Ampicillin results in increased expression of TAGLN mRNA CTD PMID:21632981 NCBI chr 8:50,222,895...50,228,369
Ensembl chr 8:50,222,896...50,231,357
JBrowse link
G Tars1 threonyl-tRNA synthetase 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TARS protein CTD PMID:30545405 NCBI chr 2:61,394,632...61,414,115
Ensembl chr 2:61,394,770...61,414,102
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases expression ISO Ampicillin results in decreased expression of TIMP1 mRNA CTD PMID:21632981 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TM9SF2 protein CTD PMID:30545405 NCBI chr15:108,526,341...108,579,268
Ensembl chr15:108,526,014...108,579,256
JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TMED10 protein CTD PMID:30545405 NCBI chr 6:109,169,739...109,205,004
Ensembl chr 6:109,169,741...109,205,004
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]
[Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of TNF protein; Dextran Sulfate inhibits the reaction [[Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of TNF protein]
CTD PMID:21893697, PMID:31442584 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tpm4 tropomyosin 4 increases expression ISO Ampicillin results in increased expression of TPM4 mRNA CTD PMID:21632981 NCBI chr16:19,385,810...19,399,851
Ensembl chr16:19,385,736...19,399,903
JBrowse link
G Trim16 tripartite motif-containing 16 increases expression ISO Ampicillin results in increased expression of TRIM16 mRNA CTD PMID:22609641 NCBI chr10:49,231,660...49,254,653
Ensembl chr10:49,231,730...49,254,621
JBrowse link
G Ttyh3 tweety family member 3 increases expression ISO Ampicillin results in increased expression of TTYH3 mRNA CTD PMID:21632981 NCBI chr12:16,084,078...16,112,672
Ensembl chr12:16,084,266...16,112,664
JBrowse link
G Tubal3 tubulin, alpha-like 3 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TUBAL3 protein CTD PMID:30545405 NCBI chr17:69,974,272...69,982,957
Ensembl chr17:69,974,272...69,982,957
JBrowse link
G Tubb1 tubulin, beta 1 class VI increases expression ISO Ampicillin results in increased expression of TUBB1 mRNA CTD PMID:21632981 NCBI chr 3:172,550,252...172,558,089
Ensembl chr 3:172,550,258...172,558,114
JBrowse link
G Tube1 tubulin, epsilon 1 decreases expression ISO Ampicillin results in decreased expression of TUBE1 mRNA CTD PMID:21632981 NCBI chr20:44,220,823...44,238,830
Ensembl chr20:44,220,840...44,238,830
JBrowse link
G Twf1 twinfilin actin-binding protein 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TWF1 protein CTD PMID:30545405 NCBI chr 7:135,838,647...135,850,542
Ensembl chr 7:135,838,648...135,850,542
JBrowse link
G Txndc5 thioredoxin domain containing 5 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TXNDC5 protein CTD PMID:30545405 NCBI chr17:26,925,828...26,953,981
Ensembl chr17:26,925,828...26,953,970
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of UQCRC1 protein CTD PMID:30545405 NCBI chr 8:117,679,328...117,691,073
Ensembl chr 8:117,679,278...117,691,071
JBrowse link
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of UQCRFS1 protein CTD PMID:30545405 NCBI chr17:35,677,984...35,682,262
Ensembl chr17:35,677,984...35,682,259
JBrowse link
G Uqcrh ubiquinol-cytochrome c reductase hinge protein multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of UQCRH protein CTD PMID:30545405 NCBI chr 5:134,919,040...134,927,235
Ensembl chr 5:134,919,044...134,927,235
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]] CTD PMID:21893697 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vldlr very low density lipoprotein receptor decreases expression ISO Ampicillin results in decreased expression of VLDLR mRNA CTD PMID:21632981 NCBI chr 1:245,236,819...245,273,688
Ensembl chr 1:245,237,736...245,269,205
JBrowse link
benzylpenicillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases activity
multiple interactions
EXP
ISO
Penicillin G results in increased activity of ABCC2 protein
Penicillin G promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]
CTD PMID:12702717, PMID:15904671 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases transport ISO ABCC4 protein results in increased transport of Penicillin G CTD PMID:17939016 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of ACACA mRNA
Penicillin G results in increased expression of ACACA mRNA
CTD PMID:27503388 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acly ATP citrate lyase increases expression
multiple interactions
ISO Penicillin G results in increased expression of ACLY mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of ACLY mRNA
CTD PMID:27503388 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Afp alpha-fetoprotein affects expression
decreases expression
ISO Penicillin G affects the expression of AFP mRNA
Penicillin G results in decreased expression of AFP mRNA
CTD PMID:24737281, PMID:25137620, PMID:26272751 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Anxa8 annexin A8 decreases expression ISO Penicillin G results in decreased expression of ANXA8 mRNA CTD PMID:24737281 NCBI chr16:10,417,174...10,432,388
Ensembl chr16:10,417,185...10,432,393
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Penicillin G results in increased expression of ATF3 mRNA CTD PMID:27965148 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of CCL2 mRNA
Penicillin G results in increased expression of CCL2 mRNA
CTD PMID:27503388 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of CCR2 mRNA CTD PMID:27503388
G Cd36 CD36 molecule multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of CD36 mRNA
Penicillin G results in increased expression of CD36 mRNA
CTD PMID:27503388 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd86 CD86 molecule increases expression ISO Penicillin G results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist increases expression ISO Penicillin G results in increased expression of CER1 mRNA CTD PMID:26272751 NCBI chr 5:101,003,019...101,006,375
Ensembl chr 5:101,003,023...101,006,375
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Penicillin G results in increased expression of CES1 mRNA CTD PMID:22609641 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of CPT1A mRNA CTD PMID:27503388 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Crp C-reactive protein multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of CRP mRNA CTD PMID:27503388 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cs citrate synthase multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of CS mRNA
Penicillin G results in increased expression of CS mRNA
CTD PMID:27503388 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Dcn decorin decreases expression ISO Penicillin G results in decreased expression of DCN mRNA CTD PMID:24737281 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Defb1 defensin beta 1 decreases expression
multiple interactions
ISO Penicillin G results in decreased expression of DEFB1 mRNA
[Penicillin G co-treated with Erythromycin] results in decreased expression of DEFB1 mRNA
CTD PMID:27503388 NCBI chr16:75,294,385...75,309,127
Ensembl chr16:75,294,376...75,309,176
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of DGAT1 mRNA CTD PMID:27503388 NCBI chr 7:117,566,363...117,576,735
Ensembl chr 7:117,566,368...117,576,737
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of DGAT2 mRNA CTD PMID:27503388 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Fabp1 fatty acid binding protein 1 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of FABP1 mRNA CTD PMID:27503388 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fasn fatty acid synthase multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of FASN mRNA
Penicillin G results in increased expression of FASN mRNA
CTD PMID:27503388 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Frzb frizzled-related protein decreases expression ISO Penicillin G results in decreased expression of FRZB mRNA CTD PMID:24737281 NCBI chr 3:67,635,604...67,668,772
Ensembl chr 3:67,635,607...67,668,772
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Penicillin G results in increased expression of GCLM mRNA CTD PMID:22609641 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression
multiple interactions
ISO Penicillin G results in increased expression of GPAM mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of GPAM mRNA
CTD PMID:27503388 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G Hdac7 histone deacetylase 7 increases expression ISO Penicillin G results in increased expression of HDAC7 mRNA CTD PMID:26272751 NCBI chr 7:139,280,396...139,319,108
Ensembl chr 7:139,281,187...139,318,455
JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of IFNG mRNA
Penicillin G results in increased expression of IFNG mRNA
CTD PMID:27503388 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf2 insulin-like growth factor 2 decreases expression ISO Penicillin G results in decreased expression of IGF2 mRNA CTD PMID:24737281 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO Penicillin G results in decreased expression of IGFBP5 mRNA CTD PMID:24737281 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Il18 interleukin 18 increases expression ISO Penicillin G results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions
ISO Penicillin G results in increased expression of IL1A mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of IL1A mRNA
CTD PMID:27503388 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Penicillin G results in increased expression of IL1B mRNA CTD PMID:22609641 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of IL6 mRNA CTD PMID:27503388 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Penicillin G results in increased expression of JUN mRNA CTD PMID:26272751 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kdr kinase insert domain receptor increases expression
decreases expression
ISO Penicillin G results in increased expression of KDR mRNA
Penicillin G results in decreased expression of KDR mRNA
CTD PMID:25137620, PMID:26272751 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Lbp lipopolysaccharide binding protein multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of LBP mRNA CTD PMID:27503388 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 decreases expression ISO Penicillin G results in decreased expression of MESP1 mRNA CTD PMID:26272751 NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908
JBrowse link
G Mmp1 matrix metallopeptidase 1 decreases expression ISO Penicillin G results in decreased expression of MMP1 mRNA CTD PMID:24737281 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression
multiple interactions
ISO Penicillin G results in increased expression of MTTP mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of MTTP mRNA
CTD PMID:27503388 NCBI chr 2:243,366,181...243,407,608
Ensembl chr 2:243,366,181...243,407,608
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in decreased expression of MUC2 mRNA CTD PMID:27503388 NCBI chr 1:214,663,929...214,693,197 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO Penicillin G results in increased expression of MYC mRNA CTD PMID:26272751 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nefm neurofilament medium affects expression ISO Penicillin G affects the expression of NEFM mRNA CTD PMID:25137620 NCBI chr15:44,855,307...44,860,604
Ensembl chr15:44,855,310...44,860,604
JBrowse link
G Nes nestin increases expression
affects expression
EXP
ISO
Penicillin G results in increased expression of NES protein
Penicillin G affects the expression of NES mRNA
CTD PMID:16137769, PMID:16369854, PMID:25137620 NCBI chr 2:187,343,109...187,352,972
Ensembl chr 2:187,344,056...187,352,969
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of NFKB1 mRNA
Penicillin G results in increased expression of NFKB1 mRNA
CTD PMID:27503388 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Penicillin G results in increased expression of NQO1 mRNA CTD PMID:22609641 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity EXP Penicillin G results in decreased activity of PGD protein CTD PMID:15558954 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pir pirin increases expression ISO Penicillin G results in increased expression of PIR mRNA CTD PMID:22609641 NCBI chr  X:31,852,322...31,968,152
Ensembl chr  X:31,852,323...31,968,152
JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 decreases expression ISO Penicillin G results in decreased expression of PNPLA6 mRNA CTD PMID:25137620 NCBI chr12:2,068,749...2,098,139
Ensembl chr12:2,069,959...2,097,904
JBrowse link
G Reg3g regenerating family member 3 gamma multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in decreased expression of REG3G mRNA CTD PMID:27503388 NCBI chr 4:109,529,679...109,532,234
Ensembl chr 4:109,529,679...109,532,234
JBrowse link
G Retnlb resistin like beta multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in decreased expression of RETNLB mRNA CTD PMID:27503388 NCBI chr11:54,565,471...54,567,578
Ensembl chr11:54,565,472...54,567,357
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of SCD1 mRNA
Penicillin G results in increased expression of SCD1 mRNA
CTD PMID:27503388 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Shh sonic hedgehog signaling molecule increases expression ISO Penicillin G results in increased expression of SHH mRNA CTD PMID:26272751 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO Potassium promotes the reaction [SLC22A12 protein results in increased uptake of Penicillin G] CTD PMID:15284287 NCBI chr 1:221,910,787...221,919,277
Ensembl chr 1:221,910,767...221,919,301
JBrowse link
G Slc22a20 solute carrier family 22 member 20 multiple interactions ISO Penicillin G inhibits the reaction [SLC22A20 protein results in increased uptake of estrone sulfate] CTD PMID:16478971 NCBI chr 1:221,327,608...221,344,367
Ensembl chr 1:221,328,711...221,343,889
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO Penicillin G inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:11602689 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions
increases uptake
EXP
ISO
Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Cimetidine]; Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Famotidine]; Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Ranitidine]
resveratrol inhibits the reaction [SLC22A8 protein results in increased uptake of Penicillin G]
CTD PMID:10224140, PMID:15319347, PMID:17255469, PMID:27377006 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Slc27a2 solute carrier family 27 member 2 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of SLC27A2 mRNA CTD PMID:27503388 NCBI chr 3:119,014,620...119,052,531
Ensembl chr 3:119,014,620...119,052,531
JBrowse link
G Slco3a1 solute carrier organic anion transporter family, member 3a1 multiple interactions ISO Penicillin G promotes the reaction [SLCO3A1 protein results in increased uptake of simvastatin acid] CTD PMID:28887287 NCBI chr 1:135,790,854...136,073,640
Ensembl chr 1:135,790,810...136,073,540
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of SREBF1 mRNA CTD PMID:27503388 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of TLR4 mRNA CTD PMID:27503388 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of TNF mRNA
Penicillin G results in increased expression of TNF mRNA
CTD PMID:27503388 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Trim16 tripartite motif-containing 16 increases expression ISO Penicillin G results in increased expression of TRIM16 mRNA CTD PMID:22609641 NCBI chr10:49,231,660...49,254,653
Ensembl chr10:49,231,730...49,254,621
JBrowse link
G Ttr transthyretin decreases expression ISO Penicillin G results in decreased expression of TTR mRNA CTD PMID:24737281 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
G Wnt3 Wnt family member 3 increases expression ISO Penicillin G results in increased expression of WNT3 mRNA CTD PMID:26272751 NCBI chr10:91,830,709...91,874,907
Ensembl chr10:91,830,654...91,874,793
JBrowse link
cloxacillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO
EXP
Cloxacillin results in decreased activity of ABCB11 protein CTD PMID:15618715 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO Cloxacillin results in increased activity of CASP3 protein
[Cloxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Cloxacillin co-treated with IL1B protein] results in increased activity of CASP3 protein; [Cloxacillin co-treated with IL6 protein] results in increased activity of CASP3 protein; [Cloxacillin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Cloxacillin results in increased activity of CASP3 protein]
CTD PMID:30876886 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Cloxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Cloxacillin co-treated with IL1B protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Cloxacillin results in increased activity of CASP3 protein] CTD PMID:30876886 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Cloxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Cloxacillin co-treated with IL6 protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Cloxacillin results in increased activity of CASP3 protein] CTD PMID:30876886 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Cloxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Cloxacillin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Cloxacillin results in increased activity of CASP3 protein] CTD PMID:30876886 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
dicloxacillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Dicloxacillin results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions
increases expression
ISO AGER protein affects the reaction [Dicloxacillin results in increased expression of GPT protein]
Dicloxacillin results in increased expression of AGER mRNA
CTD PMID:24747151 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression
ISO [Progesterone co-treated with Dicloxacillin] results in increased expression of CXCL2 mRNA
Dicloxacillin results in increased expression of CXCL2 mRNA
CTD PMID:22157104, PMID:24747151 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression
multiple interactions
ISO Dicloxacillin results in increased expression of CXCL1 mRNA
Progesterone promotes the reaction [Dicloxacillin results in increased expression of CXCL1 mRNA]
CTD PMID:22157104 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases expression
ISO AGER protein affects the reaction [Dicloxacillin results in increased expression of GPT protein]; eritoran inhibits the reaction [Dicloxacillin results in increased expression of GPT protein] CTD PMID:24747151 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Hmgb1 high mobility group box 1 increases expression ISO Dicloxacillin results in increased expression of HMGB1 protein CTD PMID:24747151 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Dicloxacillin results in increased expression of ICAM1 protein CTD PMID:14729754 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Dicloxacillin results in increased expression of IL1B mRNA CTD PMID:24747151 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 increases response to substance
increases expression
ISO IL4 results in increased susceptibility to Dicloxacillin
Dicloxacillin results in increased expression of IL4 protein
CTD PMID:21094227 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO Dicloxacillin results in increased expression of NLRP3 mRNA CTD PMID:24747151 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Dicloxacillin results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO Dicloxacillin results in increased expression of S100A8 mRNA CTD PMID:24747151, PMID:28138970 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Dicloxacillin results in increased expression of S100A9 mRNA CTD PMID:24747151 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
flucloxacillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions
ISO Floxacillin results in decreased activity of ABCB11 protein
Floxacillin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:24014644 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Floxacillin results in increased expression of AKR1B10 mRNA CTD PMID:28444390 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO Floxacillin results in increased activity of CASP3 protein
[Floxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Floxacillin co-treated with IL1B protein] results in increased activity of CASP3 protein; [Floxacillin co-treated with IL6 protein] results in increased activity of CASP3 protein; [Floxacillin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Floxacillin results in increased activity of CASP3 protein]
CTD PMID:30876886 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Floxacillin results in increased expression of CCL2 mRNA CTD PMID:24652713 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO [Floxacillin co-treated with CpG ODN 1826] results in decreased expression of CD69 protein CTD PMID:30993380 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
JBrowse link
G Crp C-reactive protein multiple interactions ISO [Floxacillin co-treated with Gentamicins co-treated with Rifampin] results in increased expression of CRP protein CTD PMID:16943303 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO Floxacillin results in increased expression of CXCL2 mRNA CTD PMID:24652713 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO Floxacillin results in increased expression of CXCL1 mRNA CTD PMID:24652713 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Faslg Fas ligand multiple interactions ISO [Floxacillin co-treated with CpG ODN 1826] results in decreased expression of FASL protein; FASL protein affects the reaction [[Floxacillin co-treated with CpG ODN 1826] results in increased expression of GPT protein] CTD PMID:30993380 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases expression
ISO [Floxacillin co-treated with alpha-galactosylceramide] results in increased expression of GPT protein; [Floxacillin co-treated with CpG ODN 1826] results in increased expression of GPT protein; FASL protein affects the reaction [[Floxacillin co-treated with CpG ODN 1826] results in increased expression of GPT protein]; IL17A protein promotes the reaction [Floxacillin results in increased expression of GPT protein] CTD PMID:24652713, PMID:30993380 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Hmgb1 high mobility group box 1 increases secretion
increases expression
ISO Floxacillin results in increased secretion of HMGB1 protein
Floxacillin results in increased expression of HMGB1 protein
CTD PMID:24652713, PMID:28444390 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Il17a interleukin 17A multiple interactions ISO [IL17A protein co-treated with Floxacillin] results in increased expression of MPO protein; IL17A protein promotes the reaction [Floxacillin results in increased expression of GPT protein] CTD PMID:24652713 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il1a interleukin 1 alpha increases secretion ISO Floxacillin results in increased secretion of IL1A protein CTD PMID:28444390 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases secretion
multiple interactions
increases expression
ISO Floxacillin results in increased secretion of IL1B protein
[Floxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Floxacillin co-treated with IL1B protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Floxacillin results in increased activity of CASP3 protein]
Floxacillin results in increased expression of IL1B mRNA
CTD PMID:24652713, PMID:28444390, PMID:30876886 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il5 interleukin 5 increases expression ISO Floxacillin results in increased expression of IL5 mRNA CTD PMID:24652713 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 increases secretion
multiple interactions
increases expression
ISO Floxacillin results in increased secretion of IL6 protein
[Floxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Floxacillin co-treated with IL6 protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Floxacillin results in increased activity of CASP3 protein]
Floxacillin results in increased expression of IL6 mRNA
CTD PMID:24652713, PMID:28444390, PMID:30876886 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [IL17A protein co-treated with Floxacillin] results in increased expression of MPO protein CTD PMID:24652713 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Rorc RAR-related orphan receptor C increases expression ISO Floxacillin results in increased expression of RORC mRNA CTD PMID:24652713 NCBI chr 2:195,612,471...195,636,797
Ensembl chr 2:195,617,021...195,637,630
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO Floxacillin results in increased expression of S100A8 mRNA CTD PMID:24652713 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Floxacillin results in increased expression of S100A9 mRNA CTD PMID:24652713 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Floxacillin results in increased expression of SRXN1 mRNA CTD PMID:28444390 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Tbx21 T-box transcription factor 21 decreases expression ISO Floxacillin results in decreased expression of TBX21 mRNA CTD PMID:24652713 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331
JBrowse link
G Tnf tumor necrosis factor increases secretion
multiple interactions
increases expression
ISO Floxacillin results in increased secretion of TNF protein
[Floxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Floxacillin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Floxacillin results in increased activity of CASP3 protein]
Floxacillin results in increased expression of TNF mRNA
CTD PMID:24652713, PMID:28444390, PMID:30876886 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Floxacillin results in increased expression of TXNRD1 mRNA CTD PMID:28444390 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
nafcillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity
multiple interactions
ISO Nafcillin results in increased activity of CASP3 protein
[Nafcillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Nafcillin co-treated with IL1B protein] results in increased activity of CASP3 protein; [Nafcillin co-treated with IL6 protein] results in increased activity of CASP3 protein; [Nafcillin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Nafcillin results in increased activity of CASP3 protein]
CTD PMID:30876886 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Nafcillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Nafcillin co-treated with IL1B protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Nafcillin results in increased activity of CASP3 protein] CTD PMID:30876886 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Nafcillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Nafcillin co-treated with IL6 protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Nafcillin results in increased activity of CASP3 protein] CTD PMID:30876886 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Nafcillin results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Nafcillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Nafcillin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Nafcillin results in increased activity of CASP3 protein] CTD PMID:30876886 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
phenoxymethylpenicillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D increases expression ISO Penicillin V results in increased expression of CES1 mRNA CTD PMID:22609641 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Penicillin V results in increased expression of GCLM mRNA CTD PMID:22609641 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Mir185 microRNA 185 decreases expression EXP Penicillin V results in decreased expression of MIR185 mRNA CTD PMID:22112502 NCBI chr11:86,812,702...86,812,781
Ensembl chr11:86,812,702...86,812,781
JBrowse link
G Mir296 microRNA 296 decreases expression EXP Penicillin V results in decreased expression of MIR296 mRNA CTD PMID:22112502 NCBI chr 3:172,357,490...172,357,567
Ensembl chr 3:172,357,490...172,357,567
JBrowse link
G Mir330 microRNA 330 decreases expression EXP Penicillin V results in decreased expression of MIR330 mRNA CTD PMID:22112502 NCBI chr 1:80,092,681...80,092,777
Ensembl chr 1:80,092,681...80,092,777
JBrowse link
G Mir34c microRNA 34c decreases expression EXP Penicillin V results in decreased expression of MIR34C mRNA CTD PMID:22112502 NCBI chr 8:55,492,024...55,492,100
Ensembl chr 8:55,492,024...55,492,100
JBrowse link
G Mir433 microRNA 433 decreases expression EXP Penicillin V results in decreased expression of MIR433 mRNA CTD PMID:22112502 NCBI chr 6:133,712,334...133,712,426
Ensembl chr 6:133,712,334...133,712,426
JBrowse link
G Mir484 microRNA 484 decreases expression EXP Penicillin V results in decreased expression of MIR484 mRNA CTD PMID:22112502 NCBI chr10:27,845...27,921
Ensembl chr10:27,845...27,921
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Penicillin V results in increased expression of NQO1 mRNA CTD PMID:22609641 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pir pirin increases expression ISO Penicillin V results in increased expression of PIR mRNA CTD PMID:22609641 NCBI chr  X:31,852,322...31,968,152
Ensembl chr  X:31,852,323...31,968,152
JBrowse link
G Trim16 tripartite motif-containing 16 increases expression ISO Penicillin V results in increased expression of TRIM16 mRNA CTD PMID:22609641 NCBI chr10:49,231,660...49,254,653
Ensembl chr10:49,231,730...49,254,621
JBrowse link
piperacillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 increases transport ISO ABCC4 protein results in increased transport of Piperacillin CTD PMID:17939016 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity
multiple interactions
ISO Piperacillin results in decreased activity of CYP2C8 protein
Piperacillin inhibits the reaction [CYP2C8 protein results in decreased methylation of Aminopyrine]
CTD PMID:26763401 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Ifng interferon gamma increases secretion ISO Piperacillin results in increased secretion of IFNG protein CTD PMID:29644860 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Ozone promotes the reaction [[tazobactam co-treated with Piperacillin] results in increased expression of IL1B mRNA] CTD PMID:16369182 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il22 interleukin 22 increases secretion ISO Piperacillin results in increased secretion of IL22 protein CTD PMID:29644860 NCBI chr 7:61,236,037...61,240,502
Ensembl chr 7:61,236,037...61,240,502
JBrowse link
G Mir155 microRNA 155 increases expression ISO Piperacillin results in increased expression of MIR155 mRNA CTD PMID:29644860 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir18a microRNA 18a increases expression ISO Piperacillin results in increased expression of MIR18A mRNA CTD PMID:29644860 NCBI chr15:100,180,015...100,180,110
Ensembl chr15:100,180,015...100,180,110
JBrowse link
G Mir21 microRNA 21 increases expression ISO Piperacillin results in increased expression of MIR21 mRNA CTD PMID:29644860 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO Piperacillin affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:72,771,992...72,789,861
Ensembl chr13:72,771,984...72,789,841
JBrowse link
G RT1-DMb RT1 class II, locus DMb affects expression ISO Piperacillin affects the expression of HLA-DMB mRNA CTD PMID:25811541 NCBI chr20:3,945,383...3,952,838
Ensembl chr20:5,227,045...5,234,290
JBrowse link
G Slc25a20 solute carrier family 25 member 20 multiple interactions EXP Piperacillin binds to and results in decreased activity of SLC25A20 protein; Piperacillin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine] CTD PMID:18452908 NCBI chr 8:117,455,308...117,476,762
Ensembl chr 8:117,455,262...117,476,734
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Ozone promotes the reaction [[tazobactam co-treated with Piperacillin] results in increased expression of TNF mRNA] CTD PMID:16369182 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19792
    role 19738
      biological role 19737
        aetiopathogenetic role 18869
          allergen 16933
            penicillin 262
              (2S,5R,6R)-6-[[(2S)-2-amino-2-(4-hydroxyphenyl)-1-oxoethyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
              (2S,5S,6R)-3,3-dimethyl-7-oxo-6-[(1-oxo-2-phenylethyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
              (2S,5S,6R)-6-[[(2-ethoxy-1-naphthalenyl)-oxomethyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
              (2S,5S,6R)-6-[[2-carboxy-1-oxo-2-(3-thiophenyl)ethyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
              (2S,5S,6R)-6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]-oxomethyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
              (3-oxo-1H-2-benzofuran-1-yl) (2S,5S,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 0
              (5R,6R)-6-[[[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]-oxomethyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
              (5S,6R)-6-[[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
              1-ethoxycarbonyloxyethyl (2S,5S,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 0
              2,2-dimethylpropanoyloxymethyl (2S,5S,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 0
              3,3-dimethyl-6-[[(5-methyl-3-phenyl-4-isoxazolyl)-oxomethyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
              3,3-dimethyl-7-oxo-6-[(1-oxo-2-phenoxyethyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
              6-[(2-amino-1-oxo-2-phenylethyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
              6beta-(\{5-[(p-aminophenyl)imino]pentylidene\}amino)penicillanic acid 0
              6beta-[(p-hydroxybenzylidene)amino]penicillanic acid 0
              LSM-6045 0
              LSM-6410 0
              N,N'-bis(phenylmethyl)ethane-1,2-diamine (5R,6R)-3,3-dimethyl-7-oxo-6-[(1-oxo-2-phenoxyethyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
              N-benzoylampicillin 0
              Penicillin F 0
              Penicillin K 0
              Penicillin T 0
              Penicillin X 0
              Tobicillin 0
              amoxicillin + 10
              ampicillin + 174
              apalcillin 0
              azidocillin + 0
              azlocillin 0
              benzylpenicillin + 64
              carbenicillin + 0
              carfecillin 0
              carindacillin 0
              clometocillin 0
              cloxacillin 5
              cyclacillin 0
              dicloxacillin 13
              epicillin 0
              flucloxacillin + 24
              hetacillin 0
              isopenicillin N 0
              mecillinam + 0
              metampicillin 0
              methicillin + 0
              mezlocillin 0
              nafcillin 5
              oxacillin + 5
              penicillin N 0
              penicillin O + 0
              penicillin allergen + 259
              penicillin-derived group + 0
              phenethicillin + 0
              phenoxymethylpenicillin + 11
              piperacillin + 12
              pivmecillinam + 0
              propicillin 0
              sulbenicillin + 0
              temocillin 0
              ticarcillin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19792
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19675
                    p-block element atom 19675
                      carbon group element atom 19571
                        carbon atom 19560
                          organic molecular entity 19560
                            organic group 18508
                              organic divalent group 18501
                                organodiyl group 18501
                                  carbonyl group 18404
                                    carbonyl compound 18404
                                      carboxylic acid 18079
                                        carboacyl group 17368
                                          univalent carboacyl group 17368
                                            carbamoyl group 17154
                                              carboxamide 17154
                                                lactam 8030
                                                  beta-lactam 792
                                                    beta-lactam antibiotic 780
                                                      penams 262
                                                        penicillanic acids 262
                                                          penicillanic acid 262
                                                            6-aminopenicillanic acid 262
                                                              penicillin 262
                                                                (2S,5R,6R)-6-[[(2S)-2-amino-2-(4-hydroxyphenyl)-1-oxoethyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
                                                                (2S,5S,6R)-3,3-dimethyl-7-oxo-6-[(1-oxo-2-phenylethyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
                                                                (2S,5S,6R)-6-[[(2-ethoxy-1-naphthalenyl)-oxomethyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
                                                                (2S,5S,6R)-6-[[2-carboxy-1-oxo-2-(3-thiophenyl)ethyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
                                                                (2S,5S,6R)-6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]-oxomethyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
                                                                (3-oxo-1H-2-benzofuran-1-yl) (2S,5S,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 0
                                                                (5R,6R)-6-[[[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]-oxomethyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
                                                                (5S,6R)-6-[[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
                                                                1-ethoxycarbonyloxyethyl (2S,5S,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 0
                                                                2,2-dimethylpropanoyloxymethyl (2S,5S,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 0
                                                                3,3-dimethyl-6-[[(5-methyl-3-phenyl-4-isoxazolyl)-oxomethyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
                                                                3,3-dimethyl-7-oxo-6-[(1-oxo-2-phenoxyethyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
                                                                6-[(2-amino-1-oxo-2-phenylethyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
                                                                6beta-(\{5-[(p-aminophenyl)imino]pentylidene\}amino)penicillanic acid 0
                                                                6beta-[(p-hydroxybenzylidene)amino]penicillanic acid 0
                                                                LSM-6045 0
                                                                LSM-6410 0
                                                                N,N'-bis(phenylmethyl)ethane-1,2-diamine (5R,6R)-3,3-dimethyl-7-oxo-6-[(1-oxo-2-phenoxyethyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 0
                                                                N-benzoylampicillin 0
                                                                Penicillin F 0
                                                                Penicillin K 0
                                                                Penicillin T 0
                                                                Penicillin X 0
                                                                Tobicillin 0
                                                                amoxicillin + 10
                                                                ampicillin + 174
                                                                apalcillin 0
                                                                azidocillin + 0
                                                                azlocillin 0
                                                                benzylpenicillin + 64
                                                                carbenicillin + 0
                                                                carfecillin 0
                                                                carindacillin 0
                                                                clometocillin 0
                                                                cloxacillin 5
                                                                cyclacillin 0
                                                                dicloxacillin 13
                                                                epicillin 0
                                                                flucloxacillin + 24
                                                                hetacillin 0
                                                                isopenicillin N 0
                                                                mecillinam + 0
                                                                metampicillin 0
                                                                methicillin + 0
                                                                mezlocillin 0
                                                                nafcillin 5
                                                                oxacillin + 5
                                                                penicillin N 0
                                                                penicillin O + 0
                                                                penicillin allergen + 259
                                                                penicillin-derived group + 0
                                                                phenethicillin + 0
                                                                phenoxymethylpenicillin + 11
                                                                piperacillin + 12
                                                                pivmecillinam + 0
                                                                propicillin 0
                                                                sulbenicillin + 0
                                                                temocillin 0
                                                                ticarcillin 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.